Annotation of imach/src/imach.c, revision 1.291

1.291   ! brouard     1: /* $Id: imach.c,v 1.290 2019/05/09 13:39:37 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.291   ! brouard     4:   Revision 1.290  2019/05/09 13:39:37  brouard
        !             5:   Summary: 0.99r18 unlimited number of individuals
        !             6: 
        !             7:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
        !             8: 
1.290     brouard     9:   Revision 1.289  2018/12/13 09:16:26  brouard
                     10:   Summary: Bug for young ages (<-30) will be in r17
                     11: 
1.289     brouard    12:   Revision 1.288  2018/05/02 20:58:27  brouard
                     13:   Summary: Some bugs fixed
                     14: 
1.288     brouard    15:   Revision 1.287  2018/05/01 17:57:25  brouard
                     16:   Summary: Bug fixed by providing frequencies only for non missing covariates
                     17: 
1.287     brouard    18:   Revision 1.286  2018/04/27 14:27:04  brouard
                     19:   Summary: some minor bugs
                     20: 
1.286     brouard    21:   Revision 1.285  2018/04/21 21:02:16  brouard
                     22:   Summary: Some bugs fixed, valgrind tested
                     23: 
1.285     brouard    24:   Revision 1.284  2018/04/20 05:22:13  brouard
                     25:   Summary: Computing mean and stdeviation of fixed quantitative variables
                     26: 
1.284     brouard    27:   Revision 1.283  2018/04/19 14:49:16  brouard
                     28:   Summary: Some minor bugs fixed
                     29: 
1.283     brouard    30:   Revision 1.282  2018/02/27 22:50:02  brouard
                     31:   *** empty log message ***
                     32: 
1.282     brouard    33:   Revision 1.281  2018/02/27 19:25:23  brouard
                     34:   Summary: Adding second argument for quitting
                     35: 
1.281     brouard    36:   Revision 1.280  2018/02/21 07:58:13  brouard
                     37:   Summary: 0.99r15
                     38: 
                     39:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                     40: 
1.280     brouard    41:   Revision 1.279  2017/07/20 13:35:01  brouard
                     42:   Summary: temporary working
                     43: 
1.279     brouard    44:   Revision 1.278  2017/07/19 14:09:02  brouard
                     45:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                     46: 
1.278     brouard    47:   Revision 1.277  2017/07/17 08:53:49  brouard
                     48:   Summary: BOM files can be read now
                     49: 
1.277     brouard    50:   Revision 1.276  2017/06/30 15:48:31  brouard
                     51:   Summary: Graphs improvements
                     52: 
1.276     brouard    53:   Revision 1.275  2017/06/30 13:39:33  brouard
                     54:   Summary: Saito's color
                     55: 
1.275     brouard    56:   Revision 1.274  2017/06/29 09:47:08  brouard
                     57:   Summary: Version 0.99r14
                     58: 
1.274     brouard    59:   Revision 1.273  2017/06/27 11:06:02  brouard
                     60:   Summary: More documentation on projections
                     61: 
1.273     brouard    62:   Revision 1.272  2017/06/27 10:22:40  brouard
                     63:   Summary: Color of backprojection changed from 6 to 5(yellow)
                     64: 
1.272     brouard    65:   Revision 1.271  2017/06/27 10:17:50  brouard
                     66:   Summary: Some bug with rint
                     67: 
1.271     brouard    68:   Revision 1.270  2017/05/24 05:45:29  brouard
                     69:   *** empty log message ***
                     70: 
1.270     brouard    71:   Revision 1.269  2017/05/23 08:39:25  brouard
                     72:   Summary: Code into subroutine, cleanings
                     73: 
1.269     brouard    74:   Revision 1.268  2017/05/18 20:09:32  brouard
                     75:   Summary: backprojection and confidence intervals of backprevalence
                     76: 
1.268     brouard    77:   Revision 1.267  2017/05/13 10:25:05  brouard
                     78:   Summary: temporary save for backprojection
                     79: 
1.267     brouard    80:   Revision 1.266  2017/05/13 07:26:12  brouard
                     81:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     82: 
1.266     brouard    83:   Revision 1.265  2017/04/26 16:22:11  brouard
                     84:   Summary: imach 0.99r13 Some bugs fixed
                     85: 
1.265     brouard    86:   Revision 1.264  2017/04/26 06:01:29  brouard
                     87:   Summary: Labels in graphs
                     88: 
1.264     brouard    89:   Revision 1.263  2017/04/24 15:23:15  brouard
                     90:   Summary: to save
                     91: 
1.263     brouard    92:   Revision 1.262  2017/04/18 16:48:12  brouard
                     93:   *** empty log message ***
                     94: 
1.262     brouard    95:   Revision 1.261  2017/04/05 10:14:09  brouard
                     96:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                     97: 
1.261     brouard    98:   Revision 1.260  2017/04/04 17:46:59  brouard
                     99:   Summary: Gnuplot indexations fixed (humm)
                    100: 
1.260     brouard   101:   Revision 1.259  2017/04/04 13:01:16  brouard
                    102:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    103: 
1.259     brouard   104:   Revision 1.258  2017/04/03 10:17:47  brouard
                    105:   Summary: Version 0.99r12
                    106: 
                    107:   Some cleanings, conformed with updated documentation.
                    108: 
1.258     brouard   109:   Revision 1.257  2017/03/29 16:53:30  brouard
                    110:   Summary: Temp
                    111: 
1.257     brouard   112:   Revision 1.256  2017/03/27 05:50:23  brouard
                    113:   Summary: Temporary
                    114: 
1.256     brouard   115:   Revision 1.255  2017/03/08 16:02:28  brouard
                    116:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    117: 
1.255     brouard   118:   Revision 1.254  2017/03/08 07:13:00  brouard
                    119:   Summary: Fixing data parameter line
                    120: 
1.254     brouard   121:   Revision 1.253  2016/12/15 11:59:41  brouard
                    122:   Summary: 0.99 in progress
                    123: 
1.253     brouard   124:   Revision 1.252  2016/09/15 21:15:37  brouard
                    125:   *** empty log message ***
                    126: 
1.252     brouard   127:   Revision 1.251  2016/09/15 15:01:13  brouard
                    128:   Summary: not working
                    129: 
1.251     brouard   130:   Revision 1.250  2016/09/08 16:07:27  brouard
                    131:   Summary: continue
                    132: 
1.250     brouard   133:   Revision 1.249  2016/09/07 17:14:18  brouard
                    134:   Summary: Starting values from frequencies
                    135: 
1.249     brouard   136:   Revision 1.248  2016/09/07 14:10:18  brouard
                    137:   *** empty log message ***
                    138: 
1.248     brouard   139:   Revision 1.247  2016/09/02 11:11:21  brouard
                    140:   *** empty log message ***
                    141: 
1.247     brouard   142:   Revision 1.246  2016/09/02 08:49:22  brouard
                    143:   *** empty log message ***
                    144: 
1.246     brouard   145:   Revision 1.245  2016/09/02 07:25:01  brouard
                    146:   *** empty log message ***
                    147: 
1.245     brouard   148:   Revision 1.244  2016/09/02 07:17:34  brouard
                    149:   *** empty log message ***
                    150: 
1.244     brouard   151:   Revision 1.243  2016/09/02 06:45:35  brouard
                    152:   *** empty log message ***
                    153: 
1.243     brouard   154:   Revision 1.242  2016/08/30 15:01:20  brouard
                    155:   Summary: Fixing a lots
                    156: 
1.242     brouard   157:   Revision 1.241  2016/08/29 17:17:25  brouard
                    158:   Summary: gnuplot problem in Back projection to fix
                    159: 
1.241     brouard   160:   Revision 1.240  2016/08/29 07:53:18  brouard
                    161:   Summary: Better
                    162: 
1.240     brouard   163:   Revision 1.239  2016/08/26 15:51:03  brouard
                    164:   Summary: Improvement in Powell output in order to copy and paste
                    165: 
                    166:   Author:
                    167: 
1.239     brouard   168:   Revision 1.238  2016/08/26 14:23:35  brouard
                    169:   Summary: Starting tests of 0.99
                    170: 
1.238     brouard   171:   Revision 1.237  2016/08/26 09:20:19  brouard
                    172:   Summary: to valgrind
                    173: 
1.237     brouard   174:   Revision 1.236  2016/08/25 10:50:18  brouard
                    175:   *** empty log message ***
                    176: 
1.236     brouard   177:   Revision 1.235  2016/08/25 06:59:23  brouard
                    178:   *** empty log message ***
                    179: 
1.235     brouard   180:   Revision 1.234  2016/08/23 16:51:20  brouard
                    181:   *** empty log message ***
                    182: 
1.234     brouard   183:   Revision 1.233  2016/08/23 07:40:50  brouard
                    184:   Summary: not working
                    185: 
1.233     brouard   186:   Revision 1.232  2016/08/22 14:20:21  brouard
                    187:   Summary: not working
                    188: 
1.232     brouard   189:   Revision 1.231  2016/08/22 07:17:15  brouard
                    190:   Summary: not working
                    191: 
1.231     brouard   192:   Revision 1.230  2016/08/22 06:55:53  brouard
                    193:   Summary: Not working
                    194: 
1.230     brouard   195:   Revision 1.229  2016/07/23 09:45:53  brouard
                    196:   Summary: Completing for func too
                    197: 
1.229     brouard   198:   Revision 1.228  2016/07/22 17:45:30  brouard
                    199:   Summary: Fixing some arrays, still debugging
                    200: 
1.227     brouard   201:   Revision 1.226  2016/07/12 18:42:34  brouard
                    202:   Summary: temp
                    203: 
1.226     brouard   204:   Revision 1.225  2016/07/12 08:40:03  brouard
                    205:   Summary: saving but not running
                    206: 
1.225     brouard   207:   Revision 1.224  2016/07/01 13:16:01  brouard
                    208:   Summary: Fixes
                    209: 
1.224     brouard   210:   Revision 1.223  2016/02/19 09:23:35  brouard
                    211:   Summary: temporary
                    212: 
1.223     brouard   213:   Revision 1.222  2016/02/17 08:14:50  brouard
                    214:   Summary: Probably last 0.98 stable version 0.98r6
                    215: 
1.222     brouard   216:   Revision 1.221  2016/02/15 23:35:36  brouard
                    217:   Summary: minor bug
                    218: 
1.220     brouard   219:   Revision 1.219  2016/02/15 00:48:12  brouard
                    220:   *** empty log message ***
                    221: 
1.219     brouard   222:   Revision 1.218  2016/02/12 11:29:23  brouard
                    223:   Summary: 0.99 Back projections
                    224: 
1.218     brouard   225:   Revision 1.217  2015/12/23 17:18:31  brouard
                    226:   Summary: Experimental backcast
                    227: 
1.217     brouard   228:   Revision 1.216  2015/12/18 17:32:11  brouard
                    229:   Summary: 0.98r4 Warning and status=-2
                    230: 
                    231:   Version 0.98r4 is now:
                    232:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    233:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    234:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    235: 
1.216     brouard   236:   Revision 1.215  2015/12/16 08:52:24  brouard
                    237:   Summary: 0.98r4 working
                    238: 
1.215     brouard   239:   Revision 1.214  2015/12/16 06:57:54  brouard
                    240:   Summary: temporary not working
                    241: 
1.214     brouard   242:   Revision 1.213  2015/12/11 18:22:17  brouard
                    243:   Summary: 0.98r4
                    244: 
1.213     brouard   245:   Revision 1.212  2015/11/21 12:47:24  brouard
                    246:   Summary: minor typo
                    247: 
1.212     brouard   248:   Revision 1.211  2015/11/21 12:41:11  brouard
                    249:   Summary: 0.98r3 with some graph of projected cross-sectional
                    250: 
                    251:   Author: Nicolas Brouard
                    252: 
1.211     brouard   253:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   254:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   255:   Summary: Adding ftolpl parameter
                    256:   Author: N Brouard
                    257: 
                    258:   We had difficulties to get smoothed confidence intervals. It was due
                    259:   to the period prevalence which wasn't computed accurately. The inner
                    260:   parameter ftolpl is now an outer parameter of the .imach parameter
                    261:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    262:   computation are long.
                    263: 
1.209     brouard   264:   Revision 1.208  2015/11/17 14:31:57  brouard
                    265:   Summary: temporary
                    266: 
1.208     brouard   267:   Revision 1.207  2015/10/27 17:36:57  brouard
                    268:   *** empty log message ***
                    269: 
1.207     brouard   270:   Revision 1.206  2015/10/24 07:14:11  brouard
                    271:   *** empty log message ***
                    272: 
1.206     brouard   273:   Revision 1.205  2015/10/23 15:50:53  brouard
                    274:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    275: 
1.205     brouard   276:   Revision 1.204  2015/10/01 16:20:26  brouard
                    277:   Summary: Some new graphs of contribution to likelihood
                    278: 
1.204     brouard   279:   Revision 1.203  2015/09/30 17:45:14  brouard
                    280:   Summary: looking at better estimation of the hessian
                    281: 
                    282:   Also a better criteria for convergence to the period prevalence And
                    283:   therefore adding the number of years needed to converge. (The
                    284:   prevalence in any alive state shold sum to one
                    285: 
1.203     brouard   286:   Revision 1.202  2015/09/22 19:45:16  brouard
                    287:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    288: 
1.202     brouard   289:   Revision 1.201  2015/09/15 17:34:58  brouard
                    290:   Summary: 0.98r0
                    291: 
                    292:   - Some new graphs like suvival functions
                    293:   - Some bugs fixed like model=1+age+V2.
                    294: 
1.201     brouard   295:   Revision 1.200  2015/09/09 16:53:55  brouard
                    296:   Summary: Big bug thanks to Flavia
                    297: 
                    298:   Even model=1+age+V2. did not work anymore
                    299: 
1.200     brouard   300:   Revision 1.199  2015/09/07 14:09:23  brouard
                    301:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    302: 
1.199     brouard   303:   Revision 1.198  2015/09/03 07:14:39  brouard
                    304:   Summary: 0.98q5 Flavia
                    305: 
1.198     brouard   306:   Revision 1.197  2015/09/01 18:24:39  brouard
                    307:   *** empty log message ***
                    308: 
1.197     brouard   309:   Revision 1.196  2015/08/18 23:17:52  brouard
                    310:   Summary: 0.98q5
                    311: 
1.196     brouard   312:   Revision 1.195  2015/08/18 16:28:39  brouard
                    313:   Summary: Adding a hack for testing purpose
                    314: 
                    315:   After reading the title, ftol and model lines, if the comment line has
                    316:   a q, starting with #q, the answer at the end of the run is quit. It
                    317:   permits to run test files in batch with ctest. The former workaround was
                    318:   $ echo q | imach foo.imach
                    319: 
1.195     brouard   320:   Revision 1.194  2015/08/18 13:32:00  brouard
                    321:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    322: 
1.194     brouard   323:   Revision 1.193  2015/08/04 07:17:42  brouard
                    324:   Summary: 0.98q4
                    325: 
1.193     brouard   326:   Revision 1.192  2015/07/16 16:49:02  brouard
                    327:   Summary: Fixing some outputs
                    328: 
1.192     brouard   329:   Revision 1.191  2015/07/14 10:00:33  brouard
                    330:   Summary: Some fixes
                    331: 
1.191     brouard   332:   Revision 1.190  2015/05/05 08:51:13  brouard
                    333:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    334: 
                    335:   Fix 1+age+.
                    336: 
1.190     brouard   337:   Revision 1.189  2015/04/30 14:45:16  brouard
                    338:   Summary: 0.98q2
                    339: 
1.189     brouard   340:   Revision 1.188  2015/04/30 08:27:53  brouard
                    341:   *** empty log message ***
                    342: 
1.188     brouard   343:   Revision 1.187  2015/04/29 09:11:15  brouard
                    344:   *** empty log message ***
                    345: 
1.187     brouard   346:   Revision 1.186  2015/04/23 12:01:52  brouard
                    347:   Summary: V1*age is working now, version 0.98q1
                    348: 
                    349:   Some codes had been disabled in order to simplify and Vn*age was
                    350:   working in the optimization phase, ie, giving correct MLE parameters,
                    351:   but, as usual, outputs were not correct and program core dumped.
                    352: 
1.186     brouard   353:   Revision 1.185  2015/03/11 13:26:42  brouard
                    354:   Summary: Inclusion of compile and links command line for Intel Compiler
                    355: 
1.185     brouard   356:   Revision 1.184  2015/03/11 11:52:39  brouard
                    357:   Summary: Back from Windows 8. Intel Compiler
                    358: 
1.184     brouard   359:   Revision 1.183  2015/03/10 20:34:32  brouard
                    360:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    361: 
                    362:   We use directest instead of original Powell test; probably no
                    363:   incidence on the results, but better justifications;
                    364:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    365:   wrong results.
                    366: 
1.183     brouard   367:   Revision 1.182  2015/02/12 08:19:57  brouard
                    368:   Summary: Trying to keep directest which seems simpler and more general
                    369:   Author: Nicolas Brouard
                    370: 
1.182     brouard   371:   Revision 1.181  2015/02/11 23:22:24  brouard
                    372:   Summary: Comments on Powell added
                    373: 
                    374:   Author:
                    375: 
1.181     brouard   376:   Revision 1.180  2015/02/11 17:33:45  brouard
                    377:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    378: 
1.180     brouard   379:   Revision 1.179  2015/01/04 09:57:06  brouard
                    380:   Summary: back to OS/X
                    381: 
1.179     brouard   382:   Revision 1.178  2015/01/04 09:35:48  brouard
                    383:   *** empty log message ***
                    384: 
1.178     brouard   385:   Revision 1.177  2015/01/03 18:40:56  brouard
                    386:   Summary: Still testing ilc32 on OSX
                    387: 
1.177     brouard   388:   Revision 1.176  2015/01/03 16:45:04  brouard
                    389:   *** empty log message ***
                    390: 
1.176     brouard   391:   Revision 1.175  2015/01/03 16:33:42  brouard
                    392:   *** empty log message ***
                    393: 
1.175     brouard   394:   Revision 1.174  2015/01/03 16:15:49  brouard
                    395:   Summary: Still in cross-compilation
                    396: 
1.174     brouard   397:   Revision 1.173  2015/01/03 12:06:26  brouard
                    398:   Summary: trying to detect cross-compilation
                    399: 
1.173     brouard   400:   Revision 1.172  2014/12/27 12:07:47  brouard
                    401:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    402: 
1.172     brouard   403:   Revision 1.171  2014/12/23 13:26:59  brouard
                    404:   Summary: Back from Visual C
                    405: 
                    406:   Still problem with utsname.h on Windows
                    407: 
1.171     brouard   408:   Revision 1.170  2014/12/23 11:17:12  brouard
                    409:   Summary: Cleaning some \%% back to %%
                    410: 
                    411:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    412: 
1.170     brouard   413:   Revision 1.169  2014/12/22 23:08:31  brouard
                    414:   Summary: 0.98p
                    415: 
                    416:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    417: 
1.169     brouard   418:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   419:   Summary: update
1.169     brouard   420: 
1.168     brouard   421:   Revision 1.167  2014/12/22 13:50:56  brouard
                    422:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    423: 
                    424:   Testing on Linux 64
                    425: 
1.167     brouard   426:   Revision 1.166  2014/12/22 11:40:47  brouard
                    427:   *** empty log message ***
                    428: 
1.166     brouard   429:   Revision 1.165  2014/12/16 11:20:36  brouard
                    430:   Summary: After compiling on Visual C
                    431: 
                    432:   * imach.c (Module): Merging 1.61 to 1.162
                    433: 
1.165     brouard   434:   Revision 1.164  2014/12/16 10:52:11  brouard
                    435:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    436: 
                    437:   * imach.c (Module): Merging 1.61 to 1.162
                    438: 
1.164     brouard   439:   Revision 1.163  2014/12/16 10:30:11  brouard
                    440:   * imach.c (Module): Merging 1.61 to 1.162
                    441: 
1.163     brouard   442:   Revision 1.162  2014/09/25 11:43:39  brouard
                    443:   Summary: temporary backup 0.99!
                    444: 
1.162     brouard   445:   Revision 1.1  2014/09/16 11:06:58  brouard
                    446:   Summary: With some code (wrong) for nlopt
                    447: 
                    448:   Author:
                    449: 
                    450:   Revision 1.161  2014/09/15 20:41:41  brouard
                    451:   Summary: Problem with macro SQR on Intel compiler
                    452: 
1.161     brouard   453:   Revision 1.160  2014/09/02 09:24:05  brouard
                    454:   *** empty log message ***
                    455: 
1.160     brouard   456:   Revision 1.159  2014/09/01 10:34:10  brouard
                    457:   Summary: WIN32
                    458:   Author: Brouard
                    459: 
1.159     brouard   460:   Revision 1.158  2014/08/27 17:11:51  brouard
                    461:   *** empty log message ***
                    462: 
1.158     brouard   463:   Revision 1.157  2014/08/27 16:26:55  brouard
                    464:   Summary: Preparing windows Visual studio version
                    465:   Author: Brouard
                    466: 
                    467:   In order to compile on Visual studio, time.h is now correct and time_t
                    468:   and tm struct should be used. difftime should be used but sometimes I
                    469:   just make the differences in raw time format (time(&now).
                    470:   Trying to suppress #ifdef LINUX
                    471:   Add xdg-open for __linux in order to open default browser.
                    472: 
1.157     brouard   473:   Revision 1.156  2014/08/25 20:10:10  brouard
                    474:   *** empty log message ***
                    475: 
1.156     brouard   476:   Revision 1.155  2014/08/25 18:32:34  brouard
                    477:   Summary: New compile, minor changes
                    478:   Author: Brouard
                    479: 
1.155     brouard   480:   Revision 1.154  2014/06/20 17:32:08  brouard
                    481:   Summary: Outputs now all graphs of convergence to period prevalence
                    482: 
1.154     brouard   483:   Revision 1.153  2014/06/20 16:45:46  brouard
                    484:   Summary: If 3 live state, convergence to period prevalence on same graph
                    485:   Author: Brouard
                    486: 
1.153     brouard   487:   Revision 1.152  2014/06/18 17:54:09  brouard
                    488:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    489: 
1.152     brouard   490:   Revision 1.151  2014/06/18 16:43:30  brouard
                    491:   *** empty log message ***
                    492: 
1.151     brouard   493:   Revision 1.150  2014/06/18 16:42:35  brouard
                    494:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    495:   Author: brouard
                    496: 
1.150     brouard   497:   Revision 1.149  2014/06/18 15:51:14  brouard
                    498:   Summary: Some fixes in parameter files errors
                    499:   Author: Nicolas Brouard
                    500: 
1.149     brouard   501:   Revision 1.148  2014/06/17 17:38:48  brouard
                    502:   Summary: Nothing new
                    503:   Author: Brouard
                    504: 
                    505:   Just a new packaging for OS/X version 0.98nS
                    506: 
1.148     brouard   507:   Revision 1.147  2014/06/16 10:33:11  brouard
                    508:   *** empty log message ***
                    509: 
1.147     brouard   510:   Revision 1.146  2014/06/16 10:20:28  brouard
                    511:   Summary: Merge
                    512:   Author: Brouard
                    513: 
                    514:   Merge, before building revised version.
                    515: 
1.146     brouard   516:   Revision 1.145  2014/06/10 21:23:15  brouard
                    517:   Summary: Debugging with valgrind
                    518:   Author: Nicolas Brouard
                    519: 
                    520:   Lot of changes in order to output the results with some covariates
                    521:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    522:   improve the code.
                    523:   No more memory valgrind error but a lot has to be done in order to
                    524:   continue the work of splitting the code into subroutines.
                    525:   Also, decodemodel has been improved. Tricode is still not
                    526:   optimal. nbcode should be improved. Documentation has been added in
                    527:   the source code.
                    528: 
1.144     brouard   529:   Revision 1.143  2014/01/26 09:45:38  brouard
                    530:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    531: 
                    532:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    533:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    534: 
1.143     brouard   535:   Revision 1.142  2014/01/26 03:57:36  brouard
                    536:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    537: 
                    538:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    539: 
1.142     brouard   540:   Revision 1.141  2014/01/26 02:42:01  brouard
                    541:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    542: 
1.141     brouard   543:   Revision 1.140  2011/09/02 10:37:54  brouard
                    544:   Summary: times.h is ok with mingw32 now.
                    545: 
1.140     brouard   546:   Revision 1.139  2010/06/14 07:50:17  brouard
                    547:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    548:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    549: 
1.139     brouard   550:   Revision 1.138  2010/04/30 18:19:40  brouard
                    551:   *** empty log message ***
                    552: 
1.138     brouard   553:   Revision 1.137  2010/04/29 18:11:38  brouard
                    554:   (Module): Checking covariates for more complex models
                    555:   than V1+V2. A lot of change to be done. Unstable.
                    556: 
1.137     brouard   557:   Revision 1.136  2010/04/26 20:30:53  brouard
                    558:   (Module): merging some libgsl code. Fixing computation
                    559:   of likelione (using inter/intrapolation if mle = 0) in order to
                    560:   get same likelihood as if mle=1.
                    561:   Some cleaning of code and comments added.
                    562: 
1.136     brouard   563:   Revision 1.135  2009/10/29 15:33:14  brouard
                    564:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    565: 
1.135     brouard   566:   Revision 1.134  2009/10/29 13:18:53  brouard
                    567:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    568: 
1.134     brouard   569:   Revision 1.133  2009/07/06 10:21:25  brouard
                    570:   just nforces
                    571: 
1.133     brouard   572:   Revision 1.132  2009/07/06 08:22:05  brouard
                    573:   Many tings
                    574: 
1.132     brouard   575:   Revision 1.131  2009/06/20 16:22:47  brouard
                    576:   Some dimensions resccaled
                    577: 
1.131     brouard   578:   Revision 1.130  2009/05/26 06:44:34  brouard
                    579:   (Module): Max Covariate is now set to 20 instead of 8. A
                    580:   lot of cleaning with variables initialized to 0. Trying to make
                    581:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    582: 
1.130     brouard   583:   Revision 1.129  2007/08/31 13:49:27  lievre
                    584:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    585: 
1.129     lievre    586:   Revision 1.128  2006/06/30 13:02:05  brouard
                    587:   (Module): Clarifications on computing e.j
                    588: 
1.128     brouard   589:   Revision 1.127  2006/04/28 18:11:50  brouard
                    590:   (Module): Yes the sum of survivors was wrong since
                    591:   imach-114 because nhstepm was no more computed in the age
                    592:   loop. Now we define nhstepma in the age loop.
                    593:   (Module): In order to speed up (in case of numerous covariates) we
                    594:   compute health expectancies (without variances) in a first step
                    595:   and then all the health expectancies with variances or standard
                    596:   deviation (needs data from the Hessian matrices) which slows the
                    597:   computation.
                    598:   In the future we should be able to stop the program is only health
                    599:   expectancies and graph are needed without standard deviations.
                    600: 
1.127     brouard   601:   Revision 1.126  2006/04/28 17:23:28  brouard
                    602:   (Module): Yes the sum of survivors was wrong since
                    603:   imach-114 because nhstepm was no more computed in the age
                    604:   loop. Now we define nhstepma in the age loop.
                    605:   Version 0.98h
                    606: 
1.126     brouard   607:   Revision 1.125  2006/04/04 15:20:31  lievre
                    608:   Errors in calculation of health expectancies. Age was not initialized.
                    609:   Forecasting file added.
                    610: 
                    611:   Revision 1.124  2006/03/22 17:13:53  lievre
                    612:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    613:   The log-likelihood is printed in the log file
                    614: 
                    615:   Revision 1.123  2006/03/20 10:52:43  brouard
                    616:   * imach.c (Module): <title> changed, corresponds to .htm file
                    617:   name. <head> headers where missing.
                    618: 
                    619:   * imach.c (Module): Weights can have a decimal point as for
                    620:   English (a comma might work with a correct LC_NUMERIC environment,
                    621:   otherwise the weight is truncated).
                    622:   Modification of warning when the covariates values are not 0 or
                    623:   1.
                    624:   Version 0.98g
                    625: 
                    626:   Revision 1.122  2006/03/20 09:45:41  brouard
                    627:   (Module): Weights can have a decimal point as for
                    628:   English (a comma might work with a correct LC_NUMERIC environment,
                    629:   otherwise the weight is truncated).
                    630:   Modification of warning when the covariates values are not 0 or
                    631:   1.
                    632:   Version 0.98g
                    633: 
                    634:   Revision 1.121  2006/03/16 17:45:01  lievre
                    635:   * imach.c (Module): Comments concerning covariates added
                    636: 
                    637:   * imach.c (Module): refinements in the computation of lli if
                    638:   status=-2 in order to have more reliable computation if stepm is
                    639:   not 1 month. Version 0.98f
                    640: 
                    641:   Revision 1.120  2006/03/16 15:10:38  lievre
                    642:   (Module): refinements in the computation of lli if
                    643:   status=-2 in order to have more reliable computation if stepm is
                    644:   not 1 month. Version 0.98f
                    645: 
                    646:   Revision 1.119  2006/03/15 17:42:26  brouard
                    647:   (Module): Bug if status = -2, the loglikelihood was
                    648:   computed as likelihood omitting the logarithm. Version O.98e
                    649: 
                    650:   Revision 1.118  2006/03/14 18:20:07  brouard
                    651:   (Module): varevsij Comments added explaining the second
                    652:   table of variances if popbased=1 .
                    653:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    654:   (Module): Function pstamp added
                    655:   (Module): Version 0.98d
                    656: 
                    657:   Revision 1.117  2006/03/14 17:16:22  brouard
                    658:   (Module): varevsij Comments added explaining the second
                    659:   table of variances if popbased=1 .
                    660:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    661:   (Module): Function pstamp added
                    662:   (Module): Version 0.98d
                    663: 
                    664:   Revision 1.116  2006/03/06 10:29:27  brouard
                    665:   (Module): Variance-covariance wrong links and
                    666:   varian-covariance of ej. is needed (Saito).
                    667: 
                    668:   Revision 1.115  2006/02/27 12:17:45  brouard
                    669:   (Module): One freematrix added in mlikeli! 0.98c
                    670: 
                    671:   Revision 1.114  2006/02/26 12:57:58  brouard
                    672:   (Module): Some improvements in processing parameter
                    673:   filename with strsep.
                    674: 
                    675:   Revision 1.113  2006/02/24 14:20:24  brouard
                    676:   (Module): Memory leaks checks with valgrind and:
                    677:   datafile was not closed, some imatrix were not freed and on matrix
                    678:   allocation too.
                    679: 
                    680:   Revision 1.112  2006/01/30 09:55:26  brouard
                    681:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    682: 
                    683:   Revision 1.111  2006/01/25 20:38:18  brouard
                    684:   (Module): Lots of cleaning and bugs added (Gompertz)
                    685:   (Module): Comments can be added in data file. Missing date values
                    686:   can be a simple dot '.'.
                    687: 
                    688:   Revision 1.110  2006/01/25 00:51:50  brouard
                    689:   (Module): Lots of cleaning and bugs added (Gompertz)
                    690: 
                    691:   Revision 1.109  2006/01/24 19:37:15  brouard
                    692:   (Module): Comments (lines starting with a #) are allowed in data.
                    693: 
                    694:   Revision 1.108  2006/01/19 18:05:42  lievre
                    695:   Gnuplot problem appeared...
                    696:   To be fixed
                    697: 
                    698:   Revision 1.107  2006/01/19 16:20:37  brouard
                    699:   Test existence of gnuplot in imach path
                    700: 
                    701:   Revision 1.106  2006/01/19 13:24:36  brouard
                    702:   Some cleaning and links added in html output
                    703: 
                    704:   Revision 1.105  2006/01/05 20:23:19  lievre
                    705:   *** empty log message ***
                    706: 
                    707:   Revision 1.104  2005/09/30 16:11:43  lievre
                    708:   (Module): sump fixed, loop imx fixed, and simplifications.
                    709:   (Module): If the status is missing at the last wave but we know
                    710:   that the person is alive, then we can code his/her status as -2
                    711:   (instead of missing=-1 in earlier versions) and his/her
                    712:   contributions to the likelihood is 1 - Prob of dying from last
                    713:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    714:   the healthy state at last known wave). Version is 0.98
                    715: 
                    716:   Revision 1.103  2005/09/30 15:54:49  lievre
                    717:   (Module): sump fixed, loop imx fixed, and simplifications.
                    718: 
                    719:   Revision 1.102  2004/09/15 17:31:30  brouard
                    720:   Add the possibility to read data file including tab characters.
                    721: 
                    722:   Revision 1.101  2004/09/15 10:38:38  brouard
                    723:   Fix on curr_time
                    724: 
                    725:   Revision 1.100  2004/07/12 18:29:06  brouard
                    726:   Add version for Mac OS X. Just define UNIX in Makefile
                    727: 
                    728:   Revision 1.99  2004/06/05 08:57:40  brouard
                    729:   *** empty log message ***
                    730: 
                    731:   Revision 1.98  2004/05/16 15:05:56  brouard
                    732:   New version 0.97 . First attempt to estimate force of mortality
                    733:   directly from the data i.e. without the need of knowing the health
                    734:   state at each age, but using a Gompertz model: log u =a + b*age .
                    735:   This is the basic analysis of mortality and should be done before any
                    736:   other analysis, in order to test if the mortality estimated from the
                    737:   cross-longitudinal survey is different from the mortality estimated
                    738:   from other sources like vital statistic data.
                    739: 
                    740:   The same imach parameter file can be used but the option for mle should be -3.
                    741: 
1.133     brouard   742:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   743:   former routines in order to include the new code within the former code.
                    744: 
                    745:   The output is very simple: only an estimate of the intercept and of
                    746:   the slope with 95% confident intervals.
                    747: 
                    748:   Current limitations:
                    749:   A) Even if you enter covariates, i.e. with the
                    750:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    751:   B) There is no computation of Life Expectancy nor Life Table.
                    752: 
                    753:   Revision 1.97  2004/02/20 13:25:42  lievre
                    754:   Version 0.96d. Population forecasting command line is (temporarily)
                    755:   suppressed.
                    756: 
                    757:   Revision 1.96  2003/07/15 15:38:55  brouard
                    758:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    759:   rewritten within the same printf. Workaround: many printfs.
                    760: 
                    761:   Revision 1.95  2003/07/08 07:54:34  brouard
                    762:   * imach.c (Repository):
                    763:   (Repository): Using imachwizard code to output a more meaningful covariance
                    764:   matrix (cov(a12,c31) instead of numbers.
                    765: 
                    766:   Revision 1.94  2003/06/27 13:00:02  brouard
                    767:   Just cleaning
                    768: 
                    769:   Revision 1.93  2003/06/25 16:33:55  brouard
                    770:   (Module): On windows (cygwin) function asctime_r doesn't
                    771:   exist so I changed back to asctime which exists.
                    772:   (Module): Version 0.96b
                    773: 
                    774:   Revision 1.92  2003/06/25 16:30:45  brouard
                    775:   (Module): On windows (cygwin) function asctime_r doesn't
                    776:   exist so I changed back to asctime which exists.
                    777: 
                    778:   Revision 1.91  2003/06/25 15:30:29  brouard
                    779:   * imach.c (Repository): Duplicated warning errors corrected.
                    780:   (Repository): Elapsed time after each iteration is now output. It
                    781:   helps to forecast when convergence will be reached. Elapsed time
                    782:   is stamped in powell.  We created a new html file for the graphs
                    783:   concerning matrix of covariance. It has extension -cov.htm.
                    784: 
                    785:   Revision 1.90  2003/06/24 12:34:15  brouard
                    786:   (Module): Some bugs corrected for windows. Also, when
                    787:   mle=-1 a template is output in file "or"mypar.txt with the design
                    788:   of the covariance matrix to be input.
                    789: 
                    790:   Revision 1.89  2003/06/24 12:30:52  brouard
                    791:   (Module): Some bugs corrected for windows. Also, when
                    792:   mle=-1 a template is output in file "or"mypar.txt with the design
                    793:   of the covariance matrix to be input.
                    794: 
                    795:   Revision 1.88  2003/06/23 17:54:56  brouard
                    796:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    797: 
                    798:   Revision 1.87  2003/06/18 12:26:01  brouard
                    799:   Version 0.96
                    800: 
                    801:   Revision 1.86  2003/06/17 20:04:08  brouard
                    802:   (Module): Change position of html and gnuplot routines and added
                    803:   routine fileappend.
                    804: 
                    805:   Revision 1.85  2003/06/17 13:12:43  brouard
                    806:   * imach.c (Repository): Check when date of death was earlier that
                    807:   current date of interview. It may happen when the death was just
                    808:   prior to the death. In this case, dh was negative and likelihood
                    809:   was wrong (infinity). We still send an "Error" but patch by
                    810:   assuming that the date of death was just one stepm after the
                    811:   interview.
                    812:   (Repository): Because some people have very long ID (first column)
                    813:   we changed int to long in num[] and we added a new lvector for
                    814:   memory allocation. But we also truncated to 8 characters (left
                    815:   truncation)
                    816:   (Repository): No more line truncation errors.
                    817: 
                    818:   Revision 1.84  2003/06/13 21:44:43  brouard
                    819:   * imach.c (Repository): Replace "freqsummary" at a correct
                    820:   place. It differs from routine "prevalence" which may be called
                    821:   many times. Probs is memory consuming and must be used with
                    822:   parcimony.
                    823:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    824: 
                    825:   Revision 1.83  2003/06/10 13:39:11  lievre
                    826:   *** empty log message ***
                    827: 
                    828:   Revision 1.82  2003/06/05 15:57:20  brouard
                    829:   Add log in  imach.c and  fullversion number is now printed.
                    830: 
                    831: */
                    832: /*
                    833:    Interpolated Markov Chain
                    834: 
                    835:   Short summary of the programme:
                    836:   
1.227     brouard   837:   This program computes Healthy Life Expectancies or State-specific
                    838:   (if states aren't health statuses) Expectancies from
                    839:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    840: 
                    841:   -1- a first survey ("cross") where individuals from different ages
                    842:   are interviewed on their health status or degree of disability (in
                    843:   the case of a health survey which is our main interest)
                    844: 
                    845:   -2- at least a second wave of interviews ("longitudinal") which
                    846:   measure each change (if any) in individual health status.  Health
                    847:   expectancies are computed from the time spent in each health state
                    848:   according to a model. More health states you consider, more time is
                    849:   necessary to reach the Maximum Likelihood of the parameters involved
                    850:   in the model.  The simplest model is the multinomial logistic model
                    851:   where pij is the probability to be observed in state j at the second
                    852:   wave conditional to be observed in state i at the first
                    853:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    854:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    855:   have a more complex model than "constant and age", you should modify
                    856:   the program where the markup *Covariates have to be included here
                    857:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   858:   convergence.
                    859: 
                    860:   The advantage of this computer programme, compared to a simple
                    861:   multinomial logistic model, is clear when the delay between waves is not
                    862:   identical for each individual. Also, if a individual missed an
                    863:   intermediate interview, the information is lost, but taken into
                    864:   account using an interpolation or extrapolation.  
                    865: 
                    866:   hPijx is the probability to be observed in state i at age x+h
                    867:   conditional to the observed state i at age x. The delay 'h' can be
                    868:   split into an exact number (nh*stepm) of unobserved intermediate
                    869:   states. This elementary transition (by month, quarter,
                    870:   semester or year) is modelled as a multinomial logistic.  The hPx
                    871:   matrix is simply the matrix product of nh*stepm elementary matrices
                    872:   and the contribution of each individual to the likelihood is simply
                    873:   hPijx.
                    874: 
                    875:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   876:   of the life expectancies. It also computes the period (stable) prevalence.
                    877: 
                    878: Back prevalence and projections:
1.227     brouard   879: 
                    880:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    881:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    882:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    883:    mobilavproj)
                    884: 
                    885:     Computes the back prevalence limit for any combination of
                    886:     covariate values k at any age between ageminpar and agemaxpar and
                    887:     returns it in **bprlim. In the loops,
                    888: 
                    889:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    890:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    891: 
                    892:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   893:    Computes for any combination of covariates k and any age between bage and fage 
                    894:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    895:                        oldm=oldms;savm=savms;
1.227     brouard   896: 
1.267     brouard   897:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   898:      Computes the transition matrix starting at age 'age' over
                    899:      'nhstepm*hstepm*stepm' months (i.e. until
                    900:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   901:      nhstepm*hstepm matrices. 
                    902: 
                    903:      Returns p3mat[i][j][h] after calling
                    904:      p3mat[i][j][h]=matprod2(newm,
                    905:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    906:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    907:      oldm);
1.226     brouard   908: 
                    909: Important routines
                    910: 
                    911: - func (or funcone), computes logit (pij) distinguishing
                    912:   o fixed variables (single or product dummies or quantitative);
                    913:   o varying variables by:
                    914:    (1) wave (single, product dummies, quantitative), 
                    915:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    916:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    917:        % varying dummy (not done) or quantitative (not done);
                    918: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    919:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    920: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    921:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    922:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   923: 
1.226     brouard   924: 
                    925:   
1.133     brouard   926:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    927:            Institut national d'études démographiques, Paris.
1.126     brouard   928:   This software have been partly granted by Euro-REVES, a concerted action
                    929:   from the European Union.
                    930:   It is copyrighted identically to a GNU software product, ie programme and
                    931:   software can be distributed freely for non commercial use. Latest version
                    932:   can be accessed at http://euroreves.ined.fr/imach .
                    933: 
                    934:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    935:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    936:   
                    937:   **********************************************************************/
                    938: /*
                    939:   main
                    940:   read parameterfile
                    941:   read datafile
                    942:   concatwav
                    943:   freqsummary
                    944:   if (mle >= 1)
                    945:     mlikeli
                    946:   print results files
                    947:   if mle==1 
                    948:      computes hessian
                    949:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    950:       begin-prev-date,...
                    951:   open gnuplot file
                    952:   open html file
1.145     brouard   953:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    954:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    955:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    956:     freexexit2 possible for memory heap.
                    957: 
                    958:   h Pij x                         | pij_nom  ficrestpij
                    959:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    960:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    961:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    962: 
                    963:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    964:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    965:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    966:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    967:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    968: 
1.126     brouard   969:   forecasting if prevfcast==1 prevforecast call prevalence()
                    970:   health expectancies
                    971:   Variance-covariance of DFLE
                    972:   prevalence()
                    973:    movingaverage()
                    974:   varevsij() 
                    975:   if popbased==1 varevsij(,popbased)
                    976:   total life expectancies
                    977:   Variance of period (stable) prevalence
                    978:  end
                    979: */
                    980: 
1.187     brouard   981: /* #define DEBUG */
                    982: /* #define DEBUGBRENT */
1.203     brouard   983: /* #define DEBUGLINMIN */
                    984: /* #define DEBUGHESS */
                    985: #define DEBUGHESSIJ
1.224     brouard   986: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   987: #define POWELL /* Instead of NLOPT */
1.224     brouard   988: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   989: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    990: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   991: 
                    992: #include <math.h>
                    993: #include <stdio.h>
                    994: #include <stdlib.h>
                    995: #include <string.h>
1.226     brouard   996: #include <ctype.h>
1.159     brouard   997: 
                    998: #ifdef _WIN32
                    999: #include <io.h>
1.172     brouard  1000: #include <windows.h>
                   1001: #include <tchar.h>
1.159     brouard  1002: #else
1.126     brouard  1003: #include <unistd.h>
1.159     brouard  1004: #endif
1.126     brouard  1005: 
                   1006: #include <limits.h>
                   1007: #include <sys/types.h>
1.171     brouard  1008: 
                   1009: #if defined(__GNUC__)
                   1010: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1011: #endif
                   1012: 
1.126     brouard  1013: #include <sys/stat.h>
                   1014: #include <errno.h>
1.159     brouard  1015: /* extern int errno; */
1.126     brouard  1016: 
1.157     brouard  1017: /* #ifdef LINUX */
                   1018: /* #include <time.h> */
                   1019: /* #include "timeval.h" */
                   1020: /* #else */
                   1021: /* #include <sys/time.h> */
                   1022: /* #endif */
                   1023: 
1.126     brouard  1024: #include <time.h>
                   1025: 
1.136     brouard  1026: #ifdef GSL
                   1027: #include <gsl/gsl_errno.h>
                   1028: #include <gsl/gsl_multimin.h>
                   1029: #endif
                   1030: 
1.167     brouard  1031: 
1.162     brouard  1032: #ifdef NLOPT
                   1033: #include <nlopt.h>
                   1034: typedef struct {
                   1035:   double (* function)(double [] );
                   1036: } myfunc_data ;
                   1037: #endif
                   1038: 
1.126     brouard  1039: /* #include <libintl.h> */
                   1040: /* #define _(String) gettext (String) */
                   1041: 
1.251     brouard  1042: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1043: 
                   1044: #define GNUPLOTPROGRAM "gnuplot"
                   1045: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1046: #define FILENAMELENGTH 132
                   1047: 
                   1048: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1049: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1050: 
1.144     brouard  1051: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1052: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1053: 
                   1054: #define NINTERVMAX 8
1.144     brouard  1055: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1056: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.291   ! brouard  1057: #define NCOVMAX 20  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1058: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1059: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1060: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1061: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1062: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1063: /* #define AGESUP 130 */
1.288     brouard  1064: /* #define AGESUP 150 */
                   1065: #define AGESUP 200
1.268     brouard  1066: #define AGEINF 0
1.218     brouard  1067: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1068: #define AGEBASE 40
1.194     brouard  1069: #define AGEOVERFLOW 1.e20
1.164     brouard  1070: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1071: #ifdef _WIN32
                   1072: #define DIRSEPARATOR '\\'
                   1073: #define CHARSEPARATOR "\\"
                   1074: #define ODIRSEPARATOR '/'
                   1075: #else
1.126     brouard  1076: #define DIRSEPARATOR '/'
                   1077: #define CHARSEPARATOR "/"
                   1078: #define ODIRSEPARATOR '\\'
                   1079: #endif
                   1080: 
1.291   ! brouard  1081: /* $Id: imach.c,v 1.290 2019/05/09 13:39:37 brouard Exp $ */
1.126     brouard  1082: /* $State: Exp $ */
1.196     brouard  1083: #include "version.h"
                   1084: char version[]=__IMACH_VERSION__;
1.283     brouard  1085: char copyright[]="April 2018,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.291   ! brouard  1086: char fullversion[]="$Revision: 1.290 $ $Date: 2019/05/09 13:39:37 $"; 
1.126     brouard  1087: char strstart[80];
                   1088: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1089: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1090: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1091: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1092: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1093: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1094: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1095: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1096: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1097: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1098: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1099: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1100: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1101: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1102: int nsd=0; /**< Total number of single dummy variables (output) */
                   1103: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1104: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1105: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1106: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1107: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1108: int cptcov=0; /* Working variable */
1.290     brouard  1109: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1110: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1111: int npar=NPARMAX;
                   1112: int nlstate=2; /* Number of live states */
                   1113: int ndeath=1; /* Number of dead states */
1.130     brouard  1114: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1115: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1116: int popbased=0;
                   1117: 
                   1118: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1119: int maxwav=0; /* Maxim number of waves */
                   1120: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1121: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1122: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1123:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1124: int mle=1, weightopt=0;
1.126     brouard  1125: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1126: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1127: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1128:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1129: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1130: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1131: 
1.130     brouard  1132: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1133: double **matprod2(); /* test */
1.126     brouard  1134: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1135: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1136: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1137: 
1.136     brouard  1138: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1139: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1140: FILE *ficlog, *ficrespow;
1.130     brouard  1141: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1142: double fretone; /* Only one call to likelihood */
1.130     brouard  1143: long ipmx=0; /* Number of contributions */
1.126     brouard  1144: double sw; /* Sum of weights */
                   1145: char filerespow[FILENAMELENGTH];
                   1146: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1147: FILE *ficresilk;
                   1148: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1149: FILE *ficresprobmorprev;
                   1150: FILE *fichtm, *fichtmcov; /* Html File */
                   1151: FILE *ficreseij;
                   1152: char filerese[FILENAMELENGTH];
                   1153: FILE *ficresstdeij;
                   1154: char fileresstde[FILENAMELENGTH];
                   1155: FILE *ficrescveij;
                   1156: char filerescve[FILENAMELENGTH];
                   1157: FILE  *ficresvij;
                   1158: char fileresv[FILENAMELENGTH];
1.269     brouard  1159: 
1.126     brouard  1160: char title[MAXLINE];
1.234     brouard  1161: char model[MAXLINE]; /**< The model line */
1.217     brouard  1162: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1163: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1164: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1165: char command[FILENAMELENGTH];
                   1166: int  outcmd=0;
                   1167: 
1.217     brouard  1168: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1169: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1170: char filelog[FILENAMELENGTH]; /* Log file */
                   1171: char filerest[FILENAMELENGTH];
                   1172: char fileregp[FILENAMELENGTH];
                   1173: char popfile[FILENAMELENGTH];
                   1174: 
                   1175: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1176: 
1.157     brouard  1177: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1178: /* struct timezone tzp; */
                   1179: /* extern int gettimeofday(); */
                   1180: struct tm tml, *gmtime(), *localtime();
                   1181: 
                   1182: extern time_t time();
                   1183: 
                   1184: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1185: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1186: struct tm tm;
                   1187: 
1.126     brouard  1188: char strcurr[80], strfor[80];
                   1189: 
                   1190: char *endptr;
                   1191: long lval;
                   1192: double dval;
                   1193: 
                   1194: #define NR_END 1
                   1195: #define FREE_ARG char*
                   1196: #define FTOL 1.0e-10
                   1197: 
                   1198: #define NRANSI 
1.240     brouard  1199: #define ITMAX 200
                   1200: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1201: 
                   1202: #define TOL 2.0e-4 
                   1203: 
                   1204: #define CGOLD 0.3819660 
                   1205: #define ZEPS 1.0e-10 
                   1206: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1207: 
                   1208: #define GOLD 1.618034 
                   1209: #define GLIMIT 100.0 
                   1210: #define TINY 1.0e-20 
                   1211: 
                   1212: static double maxarg1,maxarg2;
                   1213: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1214: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1215:   
                   1216: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1217: #define rint(a) floor(a+0.5)
1.166     brouard  1218: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1219: #define mytinydouble 1.0e-16
1.166     brouard  1220: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1221: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1222: /* static double dsqrarg; */
                   1223: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1224: static double sqrarg;
                   1225: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1226: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1227: int agegomp= AGEGOMP;
                   1228: 
                   1229: int imx; 
                   1230: int stepm=1;
                   1231: /* Stepm, step in month: minimum step interpolation*/
                   1232: 
                   1233: int estepm;
                   1234: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1235: 
                   1236: int m,nb;
                   1237: long *num;
1.197     brouard  1238: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1239: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1240:                   covariate for which somebody answered excluding 
                   1241:                   undefined. Usually 2: 0 and 1. */
                   1242: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1243:                             covariate for which somebody answered including 
                   1244:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1245: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1246: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1247: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1248: double *ageexmed,*agecens;
                   1249: double dateintmean=0;
                   1250: 
                   1251: double *weight;
                   1252: int **s; /* Status */
1.141     brouard  1253: double *agedc;
1.145     brouard  1254: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1255:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1256:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1257: double **coqvar; /* Fixed quantitative covariate nqv */
                   1258: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1259: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1260: double  idx; 
                   1261: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1262: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1263: /*k          1  2   3   4     5    6    7     8    9 */
                   1264: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1265: /* Tndvar[k]    1   2   3               4          5 */
                   1266: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1267: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1268: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1269: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1270: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1271: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1272: /* Tprod[i]=k           4               7            */
                   1273: /* Tage[i]=k                  5               8      */
                   1274: /* */
                   1275: /* Type                    */
                   1276: /* V         1  2  3  4  5 */
                   1277: /*           F  F  V  V  V */
                   1278: /*           D  Q  D  D  Q */
                   1279: /*                         */
                   1280: int *TvarsD;
                   1281: int *TvarsDind;
                   1282: int *TvarsQ;
                   1283: int *TvarsQind;
                   1284: 
1.235     brouard  1285: #define MAXRESULTLINES 10
                   1286: int nresult=0;
1.258     brouard  1287: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1288: int TKresult[MAXRESULTLINES];
1.237     brouard  1289: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1290: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1291: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1292: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1293: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1294: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1295: 
1.234     brouard  1296: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1297: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1298: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1299: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1300: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1301: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1302: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1303: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1304: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1305: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1306: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1307: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1308: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1309: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1310: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1311: 
1.230     brouard  1312: int *Tvarsel; /**< Selected covariates for output */
                   1313: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1314: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1315: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1316: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1317: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1318: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1319: int *Tage;
1.227     brouard  1320: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1321: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1322: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1323: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1324: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1325: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1326: int **Tvard;
                   1327: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1328: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1329: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1330:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1331:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1332: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1333: double *lsurv, *lpop, *tpop;
                   1334: 
1.231     brouard  1335: #define FD 1; /* Fixed dummy covariate */
                   1336: #define FQ 2; /* Fixed quantitative covariate */
                   1337: #define FP 3; /* Fixed product covariate */
                   1338: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1339: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1340: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1341: #define VD 10; /* Varying dummy covariate */
                   1342: #define VQ 11; /* Varying quantitative covariate */
                   1343: #define VP 12; /* Varying product covariate */
                   1344: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1345: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1346: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1347: #define APFD 16; /* Age product * fixed dummy covariate */
                   1348: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1349: #define APVD 18; /* Age product * varying dummy covariate */
                   1350: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1351: 
                   1352: #define FTYPE 1; /* Fixed covariate */
                   1353: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1354: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1355: 
                   1356: struct kmodel{
                   1357:        int maintype; /* main type */
                   1358:        int subtype; /* subtype */
                   1359: };
                   1360: struct kmodel modell[NCOVMAX];
                   1361: 
1.143     brouard  1362: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1363: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1364: 
                   1365: /**************** split *************************/
                   1366: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1367: {
                   1368:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1369:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1370:   */ 
                   1371:   char *ss;                            /* pointer */
1.186     brouard  1372:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1373: 
                   1374:   l1 = strlen(path );                  /* length of path */
                   1375:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1376:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1377:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1378:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1379:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1380:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1381:     /* get current working directory */
                   1382:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1383: #ifdef WIN32
                   1384:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1385: #else
                   1386:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1387: #endif
1.126     brouard  1388:       return( GLOCK_ERROR_GETCWD );
                   1389:     }
                   1390:     /* got dirc from getcwd*/
                   1391:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1392:   } else {                             /* strip directory from path */
1.126     brouard  1393:     ss++;                              /* after this, the filename */
                   1394:     l2 = strlen( ss );                 /* length of filename */
                   1395:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1396:     strcpy( name, ss );                /* save file name */
                   1397:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1398:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1399:     printf(" DIRC2 = %s \n",dirc);
                   1400:   }
                   1401:   /* We add a separator at the end of dirc if not exists */
                   1402:   l1 = strlen( dirc );                 /* length of directory */
                   1403:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1404:     dirc[l1] =  DIRSEPARATOR;
                   1405:     dirc[l1+1] = 0; 
                   1406:     printf(" DIRC3 = %s \n",dirc);
                   1407:   }
                   1408:   ss = strrchr( name, '.' );           /* find last / */
                   1409:   if (ss >0){
                   1410:     ss++;
                   1411:     strcpy(ext,ss);                    /* save extension */
                   1412:     l1= strlen( name);
                   1413:     l2= strlen(ss)+1;
                   1414:     strncpy( finame, name, l1-l2);
                   1415:     finame[l1-l2]= 0;
                   1416:   }
                   1417: 
                   1418:   return( 0 );                         /* we're done */
                   1419: }
                   1420: 
                   1421: 
                   1422: /******************************************/
                   1423: 
                   1424: void replace_back_to_slash(char *s, char*t)
                   1425: {
                   1426:   int i;
                   1427:   int lg=0;
                   1428:   i=0;
                   1429:   lg=strlen(t);
                   1430:   for(i=0; i<= lg; i++) {
                   1431:     (s[i] = t[i]);
                   1432:     if (t[i]== '\\') s[i]='/';
                   1433:   }
                   1434: }
                   1435: 
1.132     brouard  1436: char *trimbb(char *out, char *in)
1.137     brouard  1437: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1438:   char *s;
                   1439:   s=out;
                   1440:   while (*in != '\0'){
1.137     brouard  1441:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1442:       in++;
                   1443:     }
                   1444:     *out++ = *in++;
                   1445:   }
                   1446:   *out='\0';
                   1447:   return s;
                   1448: }
                   1449: 
1.187     brouard  1450: /* char *substrchaine(char *out, char *in, char *chain) */
                   1451: /* { */
                   1452: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1453: /*   char *s, *t; */
                   1454: /*   t=in;s=out; */
                   1455: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1456: /*     *out++ = *in++; */
                   1457: /*   } */
                   1458: 
                   1459: /*   /\* *in matches *chain *\/ */
                   1460: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1461: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1462: /*   } */
                   1463: /*   in--; chain--; */
                   1464: /*   while ( (*in != '\0')){ */
                   1465: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1466: /*     *out++ = *in++; */
                   1467: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1468: /*   } */
                   1469: /*   *out='\0'; */
                   1470: /*   out=s; */
                   1471: /*   return out; */
                   1472: /* } */
                   1473: char *substrchaine(char *out, char *in, char *chain)
                   1474: {
                   1475:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1476:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1477: 
                   1478:   char *strloc;
                   1479: 
                   1480:   strcpy (out, in); 
                   1481:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1482:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1483:   if(strloc != NULL){ 
                   1484:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1485:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1486:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1487:   }
                   1488:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1489:   return out;
                   1490: }
                   1491: 
                   1492: 
1.145     brouard  1493: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1494: {
1.187     brouard  1495:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1496:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1497:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1498:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1499:   */
1.160     brouard  1500:   char *s, *t;
1.145     brouard  1501:   t=in;s=in;
                   1502:   while ((*in != occ) && (*in != '\0')){
                   1503:     *alocc++ = *in++;
                   1504:   }
                   1505:   if( *in == occ){
                   1506:     *(alocc)='\0';
                   1507:     s=++in;
                   1508:   }
                   1509:  
                   1510:   if (s == t) {/* occ not found */
                   1511:     *(alocc-(in-s))='\0';
                   1512:     in=s;
                   1513:   }
                   1514:   while ( *in != '\0'){
                   1515:     *blocc++ = *in++;
                   1516:   }
                   1517: 
                   1518:   *blocc='\0';
                   1519:   return t;
                   1520: }
1.137     brouard  1521: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1522: {
1.187     brouard  1523:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1524:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1525:      gives blocc="abcdef2ghi" and alocc="j".
                   1526:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1527:   */
                   1528:   char *s, *t;
                   1529:   t=in;s=in;
                   1530:   while (*in != '\0'){
                   1531:     while( *in == occ){
                   1532:       *blocc++ = *in++;
                   1533:       s=in;
                   1534:     }
                   1535:     *blocc++ = *in++;
                   1536:   }
                   1537:   if (s == t) /* occ not found */
                   1538:     *(blocc-(in-s))='\0';
                   1539:   else
                   1540:     *(blocc-(in-s)-1)='\0';
                   1541:   in=s;
                   1542:   while ( *in != '\0'){
                   1543:     *alocc++ = *in++;
                   1544:   }
                   1545: 
                   1546:   *alocc='\0';
                   1547:   return s;
                   1548: }
                   1549: 
1.126     brouard  1550: int nbocc(char *s, char occ)
                   1551: {
                   1552:   int i,j=0;
                   1553:   int lg=20;
                   1554:   i=0;
                   1555:   lg=strlen(s);
                   1556:   for(i=0; i<= lg; i++) {
1.234     brouard  1557:     if  (s[i] == occ ) j++;
1.126     brouard  1558:   }
                   1559:   return j;
                   1560: }
                   1561: 
1.137     brouard  1562: /* void cutv(char *u,char *v, char*t, char occ) */
                   1563: /* { */
                   1564: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1565: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1566: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1567: /*   int i,lg,j,p=0; */
                   1568: /*   i=0; */
                   1569: /*   lg=strlen(t); */
                   1570: /*   for(j=0; j<=lg-1; j++) { */
                   1571: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1572: /*   } */
1.126     brouard  1573: 
1.137     brouard  1574: /*   for(j=0; j<p; j++) { */
                   1575: /*     (u[j] = t[j]); */
                   1576: /*   } */
                   1577: /*      u[p]='\0'; */
1.126     brouard  1578: 
1.137     brouard  1579: /*    for(j=0; j<= lg; j++) { */
                   1580: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1581: /*   } */
                   1582: /* } */
1.126     brouard  1583: 
1.160     brouard  1584: #ifdef _WIN32
                   1585: char * strsep(char **pp, const char *delim)
                   1586: {
                   1587:   char *p, *q;
                   1588:          
                   1589:   if ((p = *pp) == NULL)
                   1590:     return 0;
                   1591:   if ((q = strpbrk (p, delim)) != NULL)
                   1592:   {
                   1593:     *pp = q + 1;
                   1594:     *q = '\0';
                   1595:   }
                   1596:   else
                   1597:     *pp = 0;
                   1598:   return p;
                   1599: }
                   1600: #endif
                   1601: 
1.126     brouard  1602: /********************** nrerror ********************/
                   1603: 
                   1604: void nrerror(char error_text[])
                   1605: {
                   1606:   fprintf(stderr,"ERREUR ...\n");
                   1607:   fprintf(stderr,"%s\n",error_text);
                   1608:   exit(EXIT_FAILURE);
                   1609: }
                   1610: /*********************** vector *******************/
                   1611: double *vector(int nl, int nh)
                   1612: {
                   1613:   double *v;
                   1614:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1615:   if (!v) nrerror("allocation failure in vector");
                   1616:   return v-nl+NR_END;
                   1617: }
                   1618: 
                   1619: /************************ free vector ******************/
                   1620: void free_vector(double*v, int nl, int nh)
                   1621: {
                   1622:   free((FREE_ARG)(v+nl-NR_END));
                   1623: }
                   1624: 
                   1625: /************************ivector *******************************/
                   1626: int *ivector(long nl,long nh)
                   1627: {
                   1628:   int *v;
                   1629:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1630:   if (!v) nrerror("allocation failure in ivector");
                   1631:   return v-nl+NR_END;
                   1632: }
                   1633: 
                   1634: /******************free ivector **************************/
                   1635: void free_ivector(int *v, long nl, long nh)
                   1636: {
                   1637:   free((FREE_ARG)(v+nl-NR_END));
                   1638: }
                   1639: 
                   1640: /************************lvector *******************************/
                   1641: long *lvector(long nl,long nh)
                   1642: {
                   1643:   long *v;
                   1644:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1645:   if (!v) nrerror("allocation failure in ivector");
                   1646:   return v-nl+NR_END;
                   1647: }
                   1648: 
                   1649: /******************free lvector **************************/
                   1650: void free_lvector(long *v, long nl, long nh)
                   1651: {
                   1652:   free((FREE_ARG)(v+nl-NR_END));
                   1653: }
                   1654: 
                   1655: /******************* imatrix *******************************/
                   1656: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1657:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1658: { 
                   1659:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1660:   int **m; 
                   1661:   
                   1662:   /* allocate pointers to rows */ 
                   1663:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1664:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1665:   m += NR_END; 
                   1666:   m -= nrl; 
                   1667:   
                   1668:   
                   1669:   /* allocate rows and set pointers to them */ 
                   1670:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1671:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1672:   m[nrl] += NR_END; 
                   1673:   m[nrl] -= ncl; 
                   1674:   
                   1675:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1676:   
                   1677:   /* return pointer to array of pointers to rows */ 
                   1678:   return m; 
                   1679: } 
                   1680: 
                   1681: /****************** free_imatrix *************************/
                   1682: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1683:       int **m;
                   1684:       long nch,ncl,nrh,nrl; 
                   1685:      /* free an int matrix allocated by imatrix() */ 
                   1686: { 
                   1687:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1688:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1689: } 
                   1690: 
                   1691: /******************* matrix *******************************/
                   1692: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1693: {
                   1694:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1695:   double **m;
                   1696: 
                   1697:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1698:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1699:   m += NR_END;
                   1700:   m -= nrl;
                   1701: 
                   1702:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1703:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1704:   m[nrl] += NR_END;
                   1705:   m[nrl] -= ncl;
                   1706: 
                   1707:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1708:   return m;
1.145     brouard  1709:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1710: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1711: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1712:    */
                   1713: }
                   1714: 
                   1715: /*************************free matrix ************************/
                   1716: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1717: {
                   1718:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1719:   free((FREE_ARG)(m+nrl-NR_END));
                   1720: }
                   1721: 
                   1722: /******************* ma3x *******************************/
                   1723: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1724: {
                   1725:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1726:   double ***m;
                   1727: 
                   1728:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1729:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1730:   m += NR_END;
                   1731:   m -= nrl;
                   1732: 
                   1733:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1734:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1735:   m[nrl] += NR_END;
                   1736:   m[nrl] -= ncl;
                   1737: 
                   1738:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1739: 
                   1740:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1741:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1742:   m[nrl][ncl] += NR_END;
                   1743:   m[nrl][ncl] -= nll;
                   1744:   for (j=ncl+1; j<=nch; j++) 
                   1745:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1746:   
                   1747:   for (i=nrl+1; i<=nrh; i++) {
                   1748:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1749:     for (j=ncl+1; j<=nch; j++) 
                   1750:       m[i][j]=m[i][j-1]+nlay;
                   1751:   }
                   1752:   return m; 
                   1753:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1754:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1755:   */
                   1756: }
                   1757: 
                   1758: /*************************free ma3x ************************/
                   1759: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1760: {
                   1761:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1762:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1763:   free((FREE_ARG)(m+nrl-NR_END));
                   1764: }
                   1765: 
                   1766: /*************** function subdirf ***********/
                   1767: char *subdirf(char fileres[])
                   1768: {
                   1769:   /* Caution optionfilefiname is hidden */
                   1770:   strcpy(tmpout,optionfilefiname);
                   1771:   strcat(tmpout,"/"); /* Add to the right */
                   1772:   strcat(tmpout,fileres);
                   1773:   return tmpout;
                   1774: }
                   1775: 
                   1776: /*************** function subdirf2 ***********/
                   1777: char *subdirf2(char fileres[], char *preop)
                   1778: {
                   1779:   
                   1780:   /* Caution optionfilefiname is hidden */
                   1781:   strcpy(tmpout,optionfilefiname);
                   1782:   strcat(tmpout,"/");
                   1783:   strcat(tmpout,preop);
                   1784:   strcat(tmpout,fileres);
                   1785:   return tmpout;
                   1786: }
                   1787: 
                   1788: /*************** function subdirf3 ***********/
                   1789: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1790: {
                   1791:   
                   1792:   /* Caution optionfilefiname is hidden */
                   1793:   strcpy(tmpout,optionfilefiname);
                   1794:   strcat(tmpout,"/");
                   1795:   strcat(tmpout,preop);
                   1796:   strcat(tmpout,preop2);
                   1797:   strcat(tmpout,fileres);
                   1798:   return tmpout;
                   1799: }
1.213     brouard  1800:  
                   1801: /*************** function subdirfext ***********/
                   1802: char *subdirfext(char fileres[], char *preop, char *postop)
                   1803: {
                   1804:   
                   1805:   strcpy(tmpout,preop);
                   1806:   strcat(tmpout,fileres);
                   1807:   strcat(tmpout,postop);
                   1808:   return tmpout;
                   1809: }
1.126     brouard  1810: 
1.213     brouard  1811: /*************** function subdirfext3 ***********/
                   1812: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1813: {
                   1814:   
                   1815:   /* Caution optionfilefiname is hidden */
                   1816:   strcpy(tmpout,optionfilefiname);
                   1817:   strcat(tmpout,"/");
                   1818:   strcat(tmpout,preop);
                   1819:   strcat(tmpout,fileres);
                   1820:   strcat(tmpout,postop);
                   1821:   return tmpout;
                   1822: }
                   1823:  
1.162     brouard  1824: char *asc_diff_time(long time_sec, char ascdiff[])
                   1825: {
                   1826:   long sec_left, days, hours, minutes;
                   1827:   days = (time_sec) / (60*60*24);
                   1828:   sec_left = (time_sec) % (60*60*24);
                   1829:   hours = (sec_left) / (60*60) ;
                   1830:   sec_left = (sec_left) %(60*60);
                   1831:   minutes = (sec_left) /60;
                   1832:   sec_left = (sec_left) % (60);
                   1833:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1834:   return ascdiff;
                   1835: }
                   1836: 
1.126     brouard  1837: /***************** f1dim *************************/
                   1838: extern int ncom; 
                   1839: extern double *pcom,*xicom;
                   1840: extern double (*nrfunc)(double []); 
                   1841:  
                   1842: double f1dim(double x) 
                   1843: { 
                   1844:   int j; 
                   1845:   double f;
                   1846:   double *xt; 
                   1847:  
                   1848:   xt=vector(1,ncom); 
                   1849:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1850:   f=(*nrfunc)(xt); 
                   1851:   free_vector(xt,1,ncom); 
                   1852:   return f; 
                   1853: } 
                   1854: 
                   1855: /*****************brent *************************/
                   1856: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1857: {
                   1858:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1859:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1860:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1861:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1862:    * returned function value. 
                   1863:   */
1.126     brouard  1864:   int iter; 
                   1865:   double a,b,d,etemp;
1.159     brouard  1866:   double fu=0,fv,fw,fx;
1.164     brouard  1867:   double ftemp=0.;
1.126     brouard  1868:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1869:   double e=0.0; 
                   1870:  
                   1871:   a=(ax < cx ? ax : cx); 
                   1872:   b=(ax > cx ? ax : cx); 
                   1873:   x=w=v=bx; 
                   1874:   fw=fv=fx=(*f)(x); 
                   1875:   for (iter=1;iter<=ITMAX;iter++) { 
                   1876:     xm=0.5*(a+b); 
                   1877:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1878:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1879:     printf(".");fflush(stdout);
                   1880:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1881: #ifdef DEBUGBRENT
1.126     brouard  1882:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1883:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1884:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1885: #endif
                   1886:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1887:       *xmin=x; 
                   1888:       return fx; 
                   1889:     } 
                   1890:     ftemp=fu;
                   1891:     if (fabs(e) > tol1) { 
                   1892:       r=(x-w)*(fx-fv); 
                   1893:       q=(x-v)*(fx-fw); 
                   1894:       p=(x-v)*q-(x-w)*r; 
                   1895:       q=2.0*(q-r); 
                   1896:       if (q > 0.0) p = -p; 
                   1897:       q=fabs(q); 
                   1898:       etemp=e; 
                   1899:       e=d; 
                   1900:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1901:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1902:       else { 
1.224     brouard  1903:                                d=p/q; 
                   1904:                                u=x+d; 
                   1905:                                if (u-a < tol2 || b-u < tol2) 
                   1906:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1907:       } 
                   1908:     } else { 
                   1909:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1910:     } 
                   1911:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1912:     fu=(*f)(u); 
                   1913:     if (fu <= fx) { 
                   1914:       if (u >= x) a=x; else b=x; 
                   1915:       SHFT(v,w,x,u) 
1.183     brouard  1916:       SHFT(fv,fw,fx,fu) 
                   1917:     } else { 
                   1918:       if (u < x) a=u; else b=u; 
                   1919:       if (fu <= fw || w == x) { 
1.224     brouard  1920:                                v=w; 
                   1921:                                w=u; 
                   1922:                                fv=fw; 
                   1923:                                fw=fu; 
1.183     brouard  1924:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1925:                                v=u; 
                   1926:                                fv=fu; 
1.183     brouard  1927:       } 
                   1928:     } 
1.126     brouard  1929:   } 
                   1930:   nrerror("Too many iterations in brent"); 
                   1931:   *xmin=x; 
                   1932:   return fx; 
                   1933: } 
                   1934: 
                   1935: /****************** mnbrak ***********************/
                   1936: 
                   1937: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1938:            double (*func)(double)) 
1.183     brouard  1939: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1940: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1941: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1942: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1943:    */
1.126     brouard  1944:   double ulim,u,r,q, dum;
                   1945:   double fu; 
1.187     brouard  1946: 
                   1947:   double scale=10.;
                   1948:   int iterscale=0;
                   1949: 
                   1950:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1951:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1952: 
                   1953: 
                   1954:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1955:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1956:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1957:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1958:   /* } */
                   1959: 
1.126     brouard  1960:   if (*fb > *fa) { 
                   1961:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1962:     SHFT(dum,*fb,*fa,dum) 
                   1963:   } 
1.126     brouard  1964:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1965:   *fc=(*func)(*cx); 
1.183     brouard  1966: #ifdef DEBUG
1.224     brouard  1967:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1968:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1969: #endif
1.224     brouard  1970:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1971:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1972:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1973:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1974:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1975:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1976:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1977:       fu=(*func)(u); 
1.163     brouard  1978: #ifdef DEBUG
                   1979:       /* f(x)=A(x-u)**2+f(u) */
                   1980:       double A, fparabu; 
                   1981:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1982:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1983:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1984:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1985:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1986:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1987:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1988:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1989: #endif 
1.184     brouard  1990: #ifdef MNBRAKORIGINAL
1.183     brouard  1991: #else
1.191     brouard  1992: /*       if (fu > *fc) { */
                   1993: /* #ifdef DEBUG */
                   1994: /*       printf("mnbrak4  fu > fc \n"); */
                   1995: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1996: /* #endif */
                   1997: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   1998: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   1999: /*     dum=u; /\* Shifting c and u *\/ */
                   2000: /*     u = *cx; */
                   2001: /*     *cx = dum; */
                   2002: /*     dum = fu; */
                   2003: /*     fu = *fc; */
                   2004: /*     *fc =dum; */
                   2005: /*       } else { /\* end *\/ */
                   2006: /* #ifdef DEBUG */
                   2007: /*       printf("mnbrak3  fu < fc \n"); */
                   2008: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2009: /* #endif */
                   2010: /*     dum=u; /\* Shifting c and u *\/ */
                   2011: /*     u = *cx; */
                   2012: /*     *cx = dum; */
                   2013: /*     dum = fu; */
                   2014: /*     fu = *fc; */
                   2015: /*     *fc =dum; */
                   2016: /*       } */
1.224     brouard  2017: #ifdef DEBUGMNBRAK
                   2018:                 double A, fparabu; 
                   2019:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2020:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2021:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2022:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2023: #endif
1.191     brouard  2024:       dum=u; /* Shifting c and u */
                   2025:       u = *cx;
                   2026:       *cx = dum;
                   2027:       dum = fu;
                   2028:       fu = *fc;
                   2029:       *fc =dum;
1.183     brouard  2030: #endif
1.162     brouard  2031:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2032: #ifdef DEBUG
1.224     brouard  2033:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2034:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2035: #endif
1.126     brouard  2036:       fu=(*func)(u); 
                   2037:       if (fu < *fc) { 
1.183     brouard  2038: #ifdef DEBUG
1.224     brouard  2039:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2040:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2041: #endif
                   2042:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2043:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2044: #ifdef DEBUG
                   2045:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2046: #endif
                   2047:       } 
1.162     brouard  2048:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2049: #ifdef DEBUG
1.224     brouard  2050:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2051:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2052: #endif
1.126     brouard  2053:       u=ulim; 
                   2054:       fu=(*func)(u); 
1.183     brouard  2055:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2056: #ifdef DEBUG
1.224     brouard  2057:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2058:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2059: #endif
1.126     brouard  2060:       u=(*cx)+GOLD*(*cx-*bx); 
                   2061:       fu=(*func)(u); 
1.224     brouard  2062: #ifdef DEBUG
                   2063:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2064:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2065: #endif
1.183     brouard  2066:     } /* end tests */
1.126     brouard  2067:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2068:     SHFT(*fa,*fb,*fc,fu) 
                   2069: #ifdef DEBUG
1.224     brouard  2070:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2071:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2072: #endif
                   2073:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2074: } 
                   2075: 
                   2076: /*************** linmin ************************/
1.162     brouard  2077: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2078: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2079: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2080: the value of func at the returned location p . This is actually all accomplished by calling the
                   2081: routines mnbrak and brent .*/
1.126     brouard  2082: int ncom; 
                   2083: double *pcom,*xicom;
                   2084: double (*nrfunc)(double []); 
                   2085:  
1.224     brouard  2086: #ifdef LINMINORIGINAL
1.126     brouard  2087: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2088: #else
                   2089: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2090: #endif
1.126     brouard  2091: { 
                   2092:   double brent(double ax, double bx, double cx, 
                   2093:               double (*f)(double), double tol, double *xmin); 
                   2094:   double f1dim(double x); 
                   2095:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2096:              double *fc, double (*func)(double)); 
                   2097:   int j; 
                   2098:   double xx,xmin,bx,ax; 
                   2099:   double fx,fb,fa;
1.187     brouard  2100: 
1.203     brouard  2101: #ifdef LINMINORIGINAL
                   2102: #else
                   2103:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2104: #endif
                   2105:   
1.126     brouard  2106:   ncom=n; 
                   2107:   pcom=vector(1,n); 
                   2108:   xicom=vector(1,n); 
                   2109:   nrfunc=func; 
                   2110:   for (j=1;j<=n;j++) { 
                   2111:     pcom[j]=p[j]; 
1.202     brouard  2112:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2113:   } 
1.187     brouard  2114: 
1.203     brouard  2115: #ifdef LINMINORIGINAL
                   2116:   xx=1.;
                   2117: #else
                   2118:   axs=0.0;
                   2119:   xxs=1.;
                   2120:   do{
                   2121:     xx= xxs;
                   2122: #endif
1.187     brouard  2123:     ax=0.;
                   2124:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2125:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2126:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2127:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2128:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2129:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2130:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2131: #ifdef LINMINORIGINAL
                   2132: #else
                   2133:     if (fx != fx){
1.224     brouard  2134:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2135:                        printf("|");
                   2136:                        fprintf(ficlog,"|");
1.203     brouard  2137: #ifdef DEBUGLINMIN
1.224     brouard  2138:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2139: #endif
                   2140:     }
1.224     brouard  2141:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2142: #endif
                   2143:   
1.191     brouard  2144: #ifdef DEBUGLINMIN
                   2145:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2146:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2147: #endif
1.224     brouard  2148: #ifdef LINMINORIGINAL
                   2149: #else
                   2150:        if(fb == fx){ /* Flat function in the direction */
                   2151:                xmin=xx;
                   2152:     *flat=1;
                   2153:        }else{
                   2154:     *flat=0;
                   2155: #endif
                   2156:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2157:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2158:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2159:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2160:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2161:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2162: #ifdef DEBUG
1.224     brouard  2163:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2164:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2165: #endif
                   2166: #ifdef LINMINORIGINAL
                   2167: #else
                   2168:                        }
1.126     brouard  2169: #endif
1.191     brouard  2170: #ifdef DEBUGLINMIN
                   2171:   printf("linmin end ");
1.202     brouard  2172:   fprintf(ficlog,"linmin end ");
1.191     brouard  2173: #endif
1.126     brouard  2174:   for (j=1;j<=n;j++) { 
1.203     brouard  2175: #ifdef LINMINORIGINAL
                   2176:     xi[j] *= xmin; 
                   2177: #else
                   2178: #ifdef DEBUGLINMIN
                   2179:     if(xxs <1.0)
                   2180:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2181: #endif
                   2182:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2183: #ifdef DEBUGLINMIN
                   2184:     if(xxs <1.0)
                   2185:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2186: #endif
                   2187: #endif
1.187     brouard  2188:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2189:   } 
1.191     brouard  2190: #ifdef DEBUGLINMIN
1.203     brouard  2191:   printf("\n");
1.191     brouard  2192:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2193:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2194:   for (j=1;j<=n;j++) { 
1.202     brouard  2195:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2196:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2197:     if(j % ncovmodel == 0){
1.191     brouard  2198:       printf("\n");
1.202     brouard  2199:       fprintf(ficlog,"\n");
                   2200:     }
1.191     brouard  2201:   }
1.203     brouard  2202: #else
1.191     brouard  2203: #endif
1.126     brouard  2204:   free_vector(xicom,1,n); 
                   2205:   free_vector(pcom,1,n); 
                   2206: } 
                   2207: 
                   2208: 
                   2209: /*************** powell ************************/
1.162     brouard  2210: /*
                   2211: Minimization of a function func of n variables. Input consists of an initial starting point
                   2212: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2213: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2214: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2215: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2216: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2217:  */
1.224     brouard  2218: #ifdef LINMINORIGINAL
                   2219: #else
                   2220:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2221:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2222: #endif
1.126     brouard  2223: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2224:            double (*func)(double [])) 
                   2225: { 
1.224     brouard  2226: #ifdef LINMINORIGINAL
                   2227:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2228:              double (*func)(double [])); 
1.224     brouard  2229: #else 
1.241     brouard  2230:  void linmin(double p[], double xi[], int n, double *fret,
                   2231:             double (*func)(double []),int *flat); 
1.224     brouard  2232: #endif
1.239     brouard  2233:  int i,ibig,j,jk,k; 
1.126     brouard  2234:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2235:   double directest;
1.126     brouard  2236:   double fp,fptt;
                   2237:   double *xits;
                   2238:   int niterf, itmp;
1.224     brouard  2239: #ifdef LINMINORIGINAL
                   2240: #else
                   2241: 
                   2242:   flatdir=ivector(1,n); 
                   2243:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2244: #endif
1.126     brouard  2245: 
                   2246:   pt=vector(1,n); 
                   2247:   ptt=vector(1,n); 
                   2248:   xit=vector(1,n); 
                   2249:   xits=vector(1,n); 
                   2250:   *fret=(*func)(p); 
                   2251:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2252:   rcurr_time = time(NULL);  
1.126     brouard  2253:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2254:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2255:     ibig=0; 
                   2256:     del=0.0; 
1.157     brouard  2257:     rlast_time=rcurr_time;
                   2258:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2259:     rcurr_time = time(NULL);  
                   2260:     curr_time = *localtime(&rcurr_time);
                   2261:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2262:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2263: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2264:     for (i=1;i<=n;i++) {
1.126     brouard  2265:       fprintf(ficrespow," %.12lf", p[i]);
                   2266:     }
1.239     brouard  2267:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2268:     printf("\n#model=  1      +     age ");
                   2269:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2270:     if(nagesqr==1){
1.241     brouard  2271:        printf("  + age*age  ");
                   2272:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2273:     }
                   2274:     for(j=1;j <=ncovmodel-2;j++){
                   2275:       if(Typevar[j]==0) {
                   2276:        printf("  +      V%d  ",Tvar[j]);
                   2277:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2278:       }else if(Typevar[j]==1) {
                   2279:        printf("  +    V%d*age ",Tvar[j]);
                   2280:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2281:       }else if(Typevar[j]==2) {
                   2282:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2283:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2284:       }
                   2285:     }
1.126     brouard  2286:     printf("\n");
1.239     brouard  2287: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2288: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2289:     fprintf(ficlog,"\n");
1.239     brouard  2290:     for(i=1,jk=1; i <=nlstate; i++){
                   2291:       for(k=1; k <=(nlstate+ndeath); k++){
                   2292:        if (k != i) {
                   2293:          printf("%d%d ",i,k);
                   2294:          fprintf(ficlog,"%d%d ",i,k);
                   2295:          for(j=1; j <=ncovmodel; j++){
                   2296:            printf("%12.7f ",p[jk]);
                   2297:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2298:            jk++; 
                   2299:          }
                   2300:          printf("\n");
                   2301:          fprintf(ficlog,"\n");
                   2302:        }
                   2303:       }
                   2304:     }
1.241     brouard  2305:     if(*iter <=3 && *iter >1){
1.157     brouard  2306:       tml = *localtime(&rcurr_time);
                   2307:       strcpy(strcurr,asctime(&tml));
                   2308:       rforecast_time=rcurr_time; 
1.126     brouard  2309:       itmp = strlen(strcurr);
                   2310:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2311:        strcurr[itmp-1]='\0';
1.162     brouard  2312:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2313:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2314:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2315:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2316:        forecast_time = *localtime(&rforecast_time);
                   2317:        strcpy(strfor,asctime(&forecast_time));
                   2318:        itmp = strlen(strfor);
                   2319:        if(strfor[itmp-1]=='\n')
                   2320:          strfor[itmp-1]='\0';
                   2321:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2322:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2323:       }
                   2324:     }
1.187     brouard  2325:     for (i=1;i<=n;i++) { /* For each direction i */
                   2326:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2327:       fptt=(*fret); 
                   2328: #ifdef DEBUG
1.203     brouard  2329:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2330:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2331: #endif
1.203     brouard  2332:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2333:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2334: #ifdef LINMINORIGINAL
1.188     brouard  2335:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2336: #else
                   2337:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2338:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2339: #endif
                   2340:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2341:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2342:                                /* because that direction will be replaced unless the gain del is small */
                   2343:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2344:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2345:                                /* with the new direction. */
                   2346:                                del=fabs(fptt-(*fret)); 
                   2347:                                ibig=i; 
1.126     brouard  2348:       } 
                   2349: #ifdef DEBUG
                   2350:       printf("%d %.12e",i,(*fret));
                   2351:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2352:       for (j=1;j<=n;j++) {
1.224     brouard  2353:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2354:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2355:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2356:       }
                   2357:       for(j=1;j<=n;j++) {
1.225     brouard  2358:                                printf(" p(%d)=%.12e",j,p[j]);
                   2359:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2360:       }
                   2361:       printf("\n");
                   2362:       fprintf(ficlog,"\n");
                   2363: #endif
1.187     brouard  2364:     } /* end loop on each direction i */
                   2365:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2366:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2367:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2368:       for(j=1;j<=n;j++) {
1.225     brouard  2369:                                if(flatdir[j] >0){
                   2370:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2371:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2372:                                }
                   2373:                                /* printf("\n"); */
                   2374:                                /* fprintf(ficlog,"\n"); */
                   2375:                        }
1.243     brouard  2376:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2377:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2378:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2379:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2380:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2381:       /* decreased of more than 3.84  */
                   2382:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2383:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2384:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2385:                        
1.188     brouard  2386:       /* Starting the program with initial values given by a former maximization will simply change */
                   2387:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2388:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2389:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2390: #ifdef DEBUG
                   2391:       int k[2],l;
                   2392:       k[0]=1;
                   2393:       k[1]=-1;
                   2394:       printf("Max: %.12e",(*func)(p));
                   2395:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2396:       for (j=1;j<=n;j++) {
                   2397:        printf(" %.12e",p[j]);
                   2398:        fprintf(ficlog," %.12e",p[j]);
                   2399:       }
                   2400:       printf("\n");
                   2401:       fprintf(ficlog,"\n");
                   2402:       for(l=0;l<=1;l++) {
                   2403:        for (j=1;j<=n;j++) {
                   2404:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2405:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2406:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2407:        }
                   2408:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2409:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2410:       }
                   2411: #endif
                   2412: 
1.224     brouard  2413: #ifdef LINMINORIGINAL
                   2414: #else
                   2415:       free_ivector(flatdir,1,n); 
                   2416: #endif
1.126     brouard  2417:       free_vector(xit,1,n); 
                   2418:       free_vector(xits,1,n); 
                   2419:       free_vector(ptt,1,n); 
                   2420:       free_vector(pt,1,n); 
                   2421:       return; 
1.192     brouard  2422:     } /* enough precision */ 
1.240     brouard  2423:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2424:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2425:       ptt[j]=2.0*p[j]-pt[j]; 
                   2426:       xit[j]=p[j]-pt[j]; 
                   2427:       pt[j]=p[j]; 
                   2428:     } 
1.181     brouard  2429:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2430: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2431:                if (*iter <=4) {
1.225     brouard  2432: #else
                   2433: #endif
1.224     brouard  2434: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2435: #else
1.161     brouard  2436:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2437: #endif
1.162     brouard  2438:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2439:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2440:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2441:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2442:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2443:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2444:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2445:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2446:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2447:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2448:       /* mu² and del² are equal when f3=f1 */
                   2449:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2450:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2451:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2452:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2453: #ifdef NRCORIGINAL
                   2454:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2455: #else
                   2456:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2457:       t= t- del*SQR(fp-fptt);
1.183     brouard  2458: #endif
1.202     brouard  2459:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2460: #ifdef DEBUG
1.181     brouard  2461:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2462:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2463:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2464:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2465:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2466:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2467:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2468:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2469: #endif
1.183     brouard  2470: #ifdef POWELLORIGINAL
                   2471:       if (t < 0.0) { /* Then we use it for new direction */
                   2472: #else
1.182     brouard  2473:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2474:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2475:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2476:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2477:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2478:       } 
1.181     brouard  2479:       if (directest < 0.0) { /* Then we use it for new direction */
                   2480: #endif
1.191     brouard  2481: #ifdef DEBUGLINMIN
1.234     brouard  2482:        printf("Before linmin in direction P%d-P0\n",n);
                   2483:        for (j=1;j<=n;j++) {
                   2484:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2485:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2486:          if(j % ncovmodel == 0){
                   2487:            printf("\n");
                   2488:            fprintf(ficlog,"\n");
                   2489:          }
                   2490:        }
1.224     brouard  2491: #endif
                   2492: #ifdef LINMINORIGINAL
1.234     brouard  2493:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2494: #else
1.234     brouard  2495:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2496:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2497: #endif
1.234     brouard  2498:        
1.191     brouard  2499: #ifdef DEBUGLINMIN
1.234     brouard  2500:        for (j=1;j<=n;j++) { 
                   2501:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2502:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2503:          if(j % ncovmodel == 0){
                   2504:            printf("\n");
                   2505:            fprintf(ficlog,"\n");
                   2506:          }
                   2507:        }
1.224     brouard  2508: #endif
1.234     brouard  2509:        for (j=1;j<=n;j++) { 
                   2510:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2511:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2512:        }
1.224     brouard  2513: #ifdef LINMINORIGINAL
                   2514: #else
1.234     brouard  2515:        for (j=1, flatd=0;j<=n;j++) {
                   2516:          if(flatdir[j]>0)
                   2517:            flatd++;
                   2518:        }
                   2519:        if(flatd >0){
1.255     brouard  2520:          printf("%d flat directions: ",flatd);
                   2521:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2522:          for (j=1;j<=n;j++) { 
                   2523:            if(flatdir[j]>0){
                   2524:              printf("%d ",j);
                   2525:              fprintf(ficlog,"%d ",j);
                   2526:            }
                   2527:          }
                   2528:          printf("\n");
                   2529:          fprintf(ficlog,"\n");
                   2530:        }
1.191     brouard  2531: #endif
1.234     brouard  2532:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2533:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2534:        
1.126     brouard  2535: #ifdef DEBUG
1.234     brouard  2536:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2537:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2538:        for(j=1;j<=n;j++){
                   2539:          printf(" %lf",xit[j]);
                   2540:          fprintf(ficlog," %lf",xit[j]);
                   2541:        }
                   2542:        printf("\n");
                   2543:        fprintf(ficlog,"\n");
1.126     brouard  2544: #endif
1.192     brouard  2545:       } /* end of t or directest negative */
1.224     brouard  2546: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2547: #else
1.234     brouard  2548:       } /* end if (fptt < fp)  */
1.192     brouard  2549: #endif
1.225     brouard  2550: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2551:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2552: #else
1.224     brouard  2553: #endif
1.234     brouard  2554:                } /* loop iteration */ 
1.126     brouard  2555: } 
1.234     brouard  2556:   
1.126     brouard  2557: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2558:   
1.235     brouard  2559:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2560:   {
1.279     brouard  2561:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2562:      *   (and selected quantitative values in nres)
                   2563:      *  by left multiplying the unit
                   2564:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2565:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2566:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2567:      * or prevalence in state 1, prevalence in state 2, 0
                   2568:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2569:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2570:      * Output is prlim.
                   2571:      * Initial matrix pimij 
                   2572:      */
1.206     brouard  2573:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2574:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2575:   /*  0,                   0                  , 1} */
                   2576:   /*
                   2577:    * and after some iteration: */
                   2578:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2579:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2580:   /*  0,                   0                  , 1} */
                   2581:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2582:   /* {0.51571254859325999, 0.4842874514067399, */
                   2583:   /*  0.51326036147820708, 0.48673963852179264} */
                   2584:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2585:     
1.126     brouard  2586:   int i, ii,j,k;
1.209     brouard  2587:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2588:   /* double **matprod2(); */ /* test */
1.218     brouard  2589:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2590:   double **newm;
1.209     brouard  2591:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2592:   int ncvloop=0;
1.288     brouard  2593:   int first=0;
1.169     brouard  2594:   
1.209     brouard  2595:   min=vector(1,nlstate);
                   2596:   max=vector(1,nlstate);
                   2597:   meandiff=vector(1,nlstate);
                   2598: 
1.218     brouard  2599:        /* Starting with matrix unity */
1.126     brouard  2600:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2601:     for (j=1;j<=nlstate+ndeath;j++){
                   2602:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2603:     }
1.169     brouard  2604:   
                   2605:   cov[1]=1.;
                   2606:   
                   2607:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2608:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2609:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2610:     ncvloop++;
1.126     brouard  2611:     newm=savm;
                   2612:     /* Covariates have to be included here again */
1.138     brouard  2613:     cov[2]=agefin;
1.187     brouard  2614:     if(nagesqr==1)
                   2615:       cov[3]= agefin*agefin;;
1.234     brouard  2616:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2617:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2618:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2619:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2620:     }
                   2621:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2622:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2623:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2624:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2625:     }
1.237     brouard  2626:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2627:       if(Dummy[Tvar[Tage[k]]]){
                   2628:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2629:       } else{
1.235     brouard  2630:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2631:       }
1.235     brouard  2632:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2633:     }
1.237     brouard  2634:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2635:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2636:       if(Dummy[Tvard[k][1]==0]){
                   2637:        if(Dummy[Tvard[k][2]==0]){
                   2638:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2639:        }else{
                   2640:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2641:        }
                   2642:       }else{
                   2643:        if(Dummy[Tvard[k][2]==0]){
                   2644:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2645:        }else{
                   2646:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2647:        }
                   2648:       }
1.234     brouard  2649:     }
1.138     brouard  2650:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2651:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2652:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2653:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2654:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2655:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2656:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2657:     
1.126     brouard  2658:     savm=oldm;
                   2659:     oldm=newm;
1.209     brouard  2660: 
                   2661:     for(j=1; j<=nlstate; j++){
                   2662:       max[j]=0.;
                   2663:       min[j]=1.;
                   2664:     }
                   2665:     for(i=1;i<=nlstate;i++){
                   2666:       sumnew=0;
                   2667:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2668:       for(j=1; j<=nlstate; j++){ 
                   2669:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2670:        max[j]=FMAX(max[j],prlim[i][j]);
                   2671:        min[j]=FMIN(min[j],prlim[i][j]);
                   2672:       }
                   2673:     }
                   2674: 
1.126     brouard  2675:     maxmax=0.;
1.209     brouard  2676:     for(j=1; j<=nlstate; j++){
                   2677:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2678:       maxmax=FMAX(maxmax,meandiff[j]);
                   2679:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2680:     } /* j loop */
1.203     brouard  2681:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2682:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2683:     if(maxmax < ftolpl){
1.209     brouard  2684:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2685:       free_vector(min,1,nlstate);
                   2686:       free_vector(max,1,nlstate);
                   2687:       free_vector(meandiff,1,nlstate);
1.126     brouard  2688:       return prlim;
                   2689:     }
1.288     brouard  2690:   } /* agefin loop */
1.208     brouard  2691:     /* After some age loop it doesn't converge */
1.288     brouard  2692:   if(!first){
                   2693:     first=1;
                   2694:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2695:   }
                   2696:   fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2697: 
1.209     brouard  2698:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2699:   free_vector(min,1,nlstate);
                   2700:   free_vector(max,1,nlstate);
                   2701:   free_vector(meandiff,1,nlstate);
1.208     brouard  2702:   
1.169     brouard  2703:   return prlim; /* should not reach here */
1.126     brouard  2704: }
                   2705: 
1.217     brouard  2706: 
                   2707:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2708: 
1.218     brouard  2709:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2710:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2711:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2712: {
1.264     brouard  2713:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2714:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2715:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2716:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2717:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2718:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2719:   /* Initial matrix pimij */
                   2720:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2721:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2722:   /*  0,                   0                  , 1} */
                   2723:   /*
                   2724:    * and after some iteration: */
                   2725:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2726:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2727:   /*  0,                   0                  , 1} */
                   2728:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2729:   /* {0.51571254859325999, 0.4842874514067399, */
                   2730:   /*  0.51326036147820708, 0.48673963852179264} */
                   2731:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2732: 
                   2733:   int i, ii,j,k;
1.247     brouard  2734:   int first=0;
1.217     brouard  2735:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2736:   /* double **matprod2(); */ /* test */
                   2737:   double **out, cov[NCOVMAX+1], **bmij();
                   2738:   double **newm;
1.218     brouard  2739:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2740:   double        **oldm, **savm;  /* for use */
                   2741: 
1.217     brouard  2742:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2743:   int ncvloop=0;
                   2744:   
                   2745:   min=vector(1,nlstate);
                   2746:   max=vector(1,nlstate);
                   2747:   meandiff=vector(1,nlstate);
                   2748: 
1.266     brouard  2749:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2750:   oldm=oldms; savm=savms;
                   2751:   
                   2752:   /* Starting with matrix unity */
                   2753:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2754:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2755:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2756:     }
                   2757:   
                   2758:   cov[1]=1.;
                   2759:   
                   2760:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2761:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2762:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2763:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2764:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2765:     ncvloop++;
1.218     brouard  2766:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2767:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2768:     /* Covariates have to be included here again */
                   2769:     cov[2]=agefin;
                   2770:     if(nagesqr==1)
                   2771:       cov[3]= agefin*agefin;;
1.242     brouard  2772:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2773:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2774:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2775:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2776:     }
                   2777:     /* for (k=1; k<=cptcovn;k++) { */
                   2778:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2779:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2780:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2781:     /* } */
                   2782:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2783:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2784:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2785:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2786:     }
                   2787:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2788:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2789:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2790:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2791:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2792:       if(Dummy[Tvar[Tage[k]]]){
                   2793:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2794:       } else{
                   2795:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2796:       }
                   2797:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2798:     }
                   2799:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2800:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2801:       if(Dummy[Tvard[k][1]==0]){
                   2802:        if(Dummy[Tvard[k][2]==0]){
                   2803:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2804:        }else{
                   2805:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2806:        }
                   2807:       }else{
                   2808:        if(Dummy[Tvard[k][2]==0]){
                   2809:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2810:        }else{
                   2811:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2812:        }
                   2813:       }
1.217     brouard  2814:     }
                   2815:     
                   2816:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2817:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2818:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2819:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2820:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2821:                /* ij should be linked to the correct index of cov */
                   2822:                /* age and covariate values ij are in 'cov', but we need to pass
                   2823:                 * ij for the observed prevalence at age and status and covariate
                   2824:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2825:                 */
                   2826:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2827:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2828:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2829:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2830:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2831:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2832:     /*         printf("%d newm= ",i); */
                   2833:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2834:     /*           printf("%f ",newm[i][j]); */
                   2835:     /*         } */
                   2836:     /*         printf("oldm * "); */
                   2837:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2838:     /*           printf("%f ",oldm[i][j]); */
                   2839:     /*         } */
1.268     brouard  2840:     /*         printf(" bmmij "); */
1.266     brouard  2841:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2842:     /*           printf("%f ",pmmij[i][j]); */
                   2843:     /*         } */
                   2844:     /*         printf("\n"); */
                   2845:     /*   } */
                   2846:     /* } */
1.217     brouard  2847:     savm=oldm;
                   2848:     oldm=newm;
1.266     brouard  2849: 
1.217     brouard  2850:     for(j=1; j<=nlstate; j++){
                   2851:       max[j]=0.;
                   2852:       min[j]=1.;
                   2853:     }
                   2854:     for(j=1; j<=nlstate; j++){ 
                   2855:       for(i=1;i<=nlstate;i++){
1.234     brouard  2856:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2857:        bprlim[i][j]= newm[i][j];
                   2858:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2859:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2860:       }
                   2861:     }
1.218     brouard  2862:                
1.217     brouard  2863:     maxmax=0.;
                   2864:     for(i=1; i<=nlstate; i++){
                   2865:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2866:       maxmax=FMAX(maxmax,meandiff[i]);
                   2867:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2868:     } /* i loop */
1.217     brouard  2869:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2870:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2871:     if(maxmax < ftolpl){
1.220     brouard  2872:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2873:       free_vector(min,1,nlstate);
                   2874:       free_vector(max,1,nlstate);
                   2875:       free_vector(meandiff,1,nlstate);
                   2876:       return bprlim;
                   2877:     }
1.288     brouard  2878:   } /* agefin loop */
1.217     brouard  2879:     /* After some age loop it doesn't converge */
1.288     brouard  2880:   if(!first){
1.247     brouard  2881:     first=1;
                   2882:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2883: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2884:   }
                   2885:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2886: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2887:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2888:   free_vector(min,1,nlstate);
                   2889:   free_vector(max,1,nlstate);
                   2890:   free_vector(meandiff,1,nlstate);
                   2891:   
                   2892:   return bprlim; /* should not reach here */
                   2893: }
                   2894: 
1.126     brouard  2895: /*************** transition probabilities ***************/ 
                   2896: 
                   2897: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2898: {
1.138     brouard  2899:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2900:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2901:      model to the ncovmodel covariates (including constant and age).
                   2902:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2903:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2904:      ncth covariate in the global vector x is given by the formula:
                   2905:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2906:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2907:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2908:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2909:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2910:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2911:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2912:   */
                   2913:   double s1, lnpijopii;
1.126     brouard  2914:   /*double t34;*/
1.164     brouard  2915:   int i,j, nc, ii, jj;
1.126     brouard  2916: 
1.223     brouard  2917:   for(i=1; i<= nlstate; i++){
                   2918:     for(j=1; j<i;j++){
                   2919:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2920:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2921:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2922:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2923:       }
                   2924:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2925:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2926:     }
                   2927:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2928:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2929:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2930:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2931:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2932:       }
                   2933:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2934:     }
                   2935:   }
1.218     brouard  2936:   
1.223     brouard  2937:   for(i=1; i<= nlstate; i++){
                   2938:     s1=0;
                   2939:     for(j=1; j<i; j++){
                   2940:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2941:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2942:     }
                   2943:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2944:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2945:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2946:     }
                   2947:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2948:     ps[i][i]=1./(s1+1.);
                   2949:     /* Computing other pijs */
                   2950:     for(j=1; j<i; j++)
                   2951:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2952:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2953:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2954:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2955:   } /* end i */
1.218     brouard  2956:   
1.223     brouard  2957:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2958:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2959:       ps[ii][jj]=0;
                   2960:       ps[ii][ii]=1;
                   2961:     }
                   2962:   }
1.218     brouard  2963:   
                   2964:   
1.223     brouard  2965:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2966:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2967:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2968:   /*   } */
                   2969:   /*   printf("\n "); */
                   2970:   /* } */
                   2971:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2972:   /*
                   2973:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2974:                goto end;*/
1.266     brouard  2975:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2976: }
                   2977: 
1.218     brouard  2978: /*************** backward transition probabilities ***************/ 
                   2979: 
                   2980:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2981: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2982:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2983: {
1.266     brouard  2984:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2985:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2986:    */
1.218     brouard  2987:   int i, ii, j,k;
1.222     brouard  2988:   
                   2989:   double **out, **pmij();
                   2990:   double sumnew=0.;
1.218     brouard  2991:   double agefin;
1.268     brouard  2992:   double k3=0.; /* constant of the w_x diagonal matrixe (in order for B to sum to 1 even for death state) */
1.222     brouard  2993:   double **dnewm, **dsavm, **doldm;
                   2994:   double **bbmij;
                   2995:   
1.218     brouard  2996:   doldm=ddoldms; /* global pointers */
1.222     brouard  2997:   dnewm=ddnewms;
                   2998:   dsavm=ddsavms;
                   2999:   
                   3000:   agefin=cov[2];
1.268     brouard  3001:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3002:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3003:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3004:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3005: 
                   3006:   /* P_x */
1.266     brouard  3007:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3008:   /* outputs pmmij which is a stochastic matrix in row */
                   3009: 
                   3010:   /* Diag(w_x) */
                   3011:   /* Problem with prevacurrent which can be zero */
                   3012:   sumnew=0.;
1.269     brouard  3013:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3014:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  3015:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  3016:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3017:   }
                   3018:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3019:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3020:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3021:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3022:     }
                   3023:   }else{
                   3024:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3025:       for (j=1;j<=nlstate+ndeath;j++)
                   3026:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3027:     }
                   3028:     /* if(sumnew <0.9){ */
                   3029:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3030:     /* } */
                   3031:   }
                   3032:   k3=0.0;  /* We put the last diagonal to 0 */
                   3033:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3034:       doldm[ii][ii]= k3;
                   3035:   }
                   3036:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3037:   
                   3038:   /* left Product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm) */
                   3039:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* Bug Valgrind */
                   3040: 
                   3041:   /* Diag(Sum_i w^i_x p^ij_x */
                   3042:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3043:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3044:     sumnew=0.;
1.222     brouard  3045:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3046:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3047:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3048:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3049:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3050:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3051:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3052:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3053:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3054:        /* }else */
1.268     brouard  3055:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3056:     } /*End ii */
                   3057:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3058: 
                   3059:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* Bug Valgrind */
                   3060:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3061:   /* end bmij */
1.266     brouard  3062:   return ps; /*pointer is unchanged */
1.218     brouard  3063: }
1.217     brouard  3064: /*************** transition probabilities ***************/ 
                   3065: 
1.218     brouard  3066: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3067: {
                   3068:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3069:      computes the probability to be observed in state j being in state i by appying the
                   3070:      model to the ncovmodel covariates (including constant and age).
                   3071:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3072:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3073:      ncth covariate in the global vector x is given by the formula:
                   3074:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3075:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3076:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3077:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3078:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3079:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3080:   */
                   3081:   double s1, lnpijopii;
                   3082:   /*double t34;*/
                   3083:   int i,j, nc, ii, jj;
                   3084: 
1.234     brouard  3085:   for(i=1; i<= nlstate; i++){
                   3086:     for(j=1; j<i;j++){
                   3087:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3088:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3089:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3090:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3091:       }
                   3092:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3093:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3094:     }
                   3095:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3096:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3097:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3098:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3099:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3100:       }
                   3101:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3102:     }
                   3103:   }
                   3104:   
                   3105:   for(i=1; i<= nlstate; i++){
                   3106:     s1=0;
                   3107:     for(j=1; j<i; j++){
                   3108:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3109:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3110:     }
                   3111:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3112:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3113:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3114:     }
                   3115:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3116:     ps[i][i]=1./(s1+1.);
                   3117:     /* Computing other pijs */
                   3118:     for(j=1; j<i; j++)
                   3119:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3120:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3121:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3122:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3123:   } /* end i */
                   3124:   
                   3125:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3126:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3127:       ps[ii][jj]=0;
                   3128:       ps[ii][ii]=1;
                   3129:     }
                   3130:   }
                   3131:   /* Added for backcast */ /* Transposed matrix too */
                   3132:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3133:     s1=0.;
                   3134:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3135:       s1+=ps[ii][jj];
                   3136:     }
                   3137:     for(ii=1; ii<= nlstate; ii++){
                   3138:       ps[ii][jj]=ps[ii][jj]/s1;
                   3139:     }
                   3140:   }
                   3141:   /* Transposition */
                   3142:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3143:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3144:       s1=ps[ii][jj];
                   3145:       ps[ii][jj]=ps[jj][ii];
                   3146:       ps[jj][ii]=s1;
                   3147:     }
                   3148:   }
                   3149:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3150:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3151:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3152:   /*   } */
                   3153:   /*   printf("\n "); */
                   3154:   /* } */
                   3155:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3156:   /*
                   3157:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3158:     goto end;*/
                   3159:   return ps;
1.217     brouard  3160: }
                   3161: 
                   3162: 
1.126     brouard  3163: /**************** Product of 2 matrices ******************/
                   3164: 
1.145     brouard  3165: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3166: {
                   3167:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3168:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3169:   /* in, b, out are matrice of pointers which should have been initialized 
                   3170:      before: only the contents of out is modified. The function returns
                   3171:      a pointer to pointers identical to out */
1.145     brouard  3172:   int i, j, k;
1.126     brouard  3173:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3174:     for(k=ncolol; k<=ncoloh; k++){
                   3175:       out[i][k]=0.;
                   3176:       for(j=ncl; j<=nch; j++)
                   3177:        out[i][k] +=in[i][j]*b[j][k];
                   3178:     }
1.126     brouard  3179:   return out;
                   3180: }
                   3181: 
                   3182: 
                   3183: /************* Higher Matrix Product ***************/
                   3184: 
1.235     brouard  3185: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3186: {
1.218     brouard  3187:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3188:      'nhstepm*hstepm*stepm' months (i.e. until
                   3189:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3190:      nhstepm*hstepm matrices. 
                   3191:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3192:      (typically every 2 years instead of every month which is too big 
                   3193:      for the memory).
                   3194:      Model is determined by parameters x and covariates have to be 
                   3195:      included manually here. 
                   3196: 
                   3197:      */
                   3198: 
                   3199:   int i, j, d, h, k;
1.131     brouard  3200:   double **out, cov[NCOVMAX+1];
1.126     brouard  3201:   double **newm;
1.187     brouard  3202:   double agexact;
1.214     brouard  3203:   double agebegin, ageend;
1.126     brouard  3204: 
                   3205:   /* Hstepm could be zero and should return the unit matrix */
                   3206:   for (i=1;i<=nlstate+ndeath;i++)
                   3207:     for (j=1;j<=nlstate+ndeath;j++){
                   3208:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3209:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3210:     }
                   3211:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3212:   for(h=1; h <=nhstepm; h++){
                   3213:     for(d=1; d <=hstepm; d++){
                   3214:       newm=savm;
                   3215:       /* Covariates have to be included here again */
                   3216:       cov[1]=1.;
1.214     brouard  3217:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3218:       cov[2]=agexact;
                   3219:       if(nagesqr==1)
1.227     brouard  3220:        cov[3]= agexact*agexact;
1.235     brouard  3221:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3222:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3223:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3224:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3225:       }
                   3226:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3227:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3228:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3229:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3230:       }
                   3231:       for (k=1; k<=cptcovage;k++){
                   3232:        if(Dummy[Tvar[Tage[k]]]){
                   3233:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3234:        } else{
                   3235:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3236:        }
                   3237:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3238:       }
                   3239:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3240:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3241:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3242:       }
                   3243:       /* for (k=1; k<=cptcovn;k++)  */
                   3244:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3245:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3246:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3247:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3248:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3249:       
                   3250:       
1.126     brouard  3251:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3252:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3253:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3254:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3255:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3256:       /* if((int)age == 70){ */
                   3257:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3258:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3259:       /*         printf("%d pmmij ",i); */
                   3260:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3261:       /*           printf("%f ",pmmij[i][j]); */
                   3262:       /*         } */
                   3263:       /*         printf(" oldm "); */
                   3264:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3265:       /*           printf("%f ",oldm[i][j]); */
                   3266:       /*         } */
                   3267:       /*         printf("\n"); */
                   3268:       /*       } */
                   3269:       /* } */
1.126     brouard  3270:       savm=oldm;
                   3271:       oldm=newm;
                   3272:     }
                   3273:     for(i=1; i<=nlstate+ndeath; i++)
                   3274:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3275:        po[i][j][h]=newm[i][j];
                   3276:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3277:       }
1.128     brouard  3278:     /*printf("h=%d ",h);*/
1.126     brouard  3279:   } /* end h */
1.267     brouard  3280:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3281:   return po;
                   3282: }
                   3283: 
1.217     brouard  3284: /************* Higher Back Matrix Product ***************/
1.218     brouard  3285: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3286: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3287: {
1.266     brouard  3288:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3289:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3290:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3291:      nhstepm*hstepm matrices.
                   3292:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3293:      (typically every 2 years instead of every month which is too big
1.217     brouard  3294:      for the memory).
1.218     brouard  3295:      Model is determined by parameters x and covariates have to be
1.266     brouard  3296:      included manually here. Then we use a call to bmij(x and cov)
                   3297:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3298:   */
1.217     brouard  3299: 
                   3300:   int i, j, d, h, k;
1.266     brouard  3301:   double **out, cov[NCOVMAX+1], **bmij();
                   3302:   double **newm, ***newmm;
1.217     brouard  3303:   double agexact;
                   3304:   double agebegin, ageend;
1.222     brouard  3305:   double **oldm, **savm;
1.217     brouard  3306: 
1.266     brouard  3307:   newmm=po; /* To be saved */
                   3308:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3309:   /* Hstepm could be zero and should return the unit matrix */
                   3310:   for (i=1;i<=nlstate+ndeath;i++)
                   3311:     for (j=1;j<=nlstate+ndeath;j++){
                   3312:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3313:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3314:     }
                   3315:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3316:   for(h=1; h <=nhstepm; h++){
                   3317:     for(d=1; d <=hstepm; d++){
                   3318:       newm=savm;
                   3319:       /* Covariates have to be included here again */
                   3320:       cov[1]=1.;
1.271     brouard  3321:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3322:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3323:       cov[2]=agexact;
                   3324:       if(nagesqr==1)
1.222     brouard  3325:        cov[3]= agexact*agexact;
1.266     brouard  3326:       for (k=1; k<=cptcovn;k++){
                   3327:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3328:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3329:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3330:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3331:       }
1.267     brouard  3332:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3333:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3334:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3335:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3336:       }
                   3337:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3338:        if(Dummy[Tvar[Tage[k]]]){
                   3339:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3340:        } else{
                   3341:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3342:        }
                   3343:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3344:       }
                   3345:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3346:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3347:       }                        
1.217     brouard  3348:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3349:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3350: 
1.218     brouard  3351:       /* Careful transposed matrix */
1.266     brouard  3352:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3353:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3354:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3355:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3356:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3357:       /* if((int)age == 70){ */
                   3358:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3359:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3360:       /*         printf("%d pmmij ",i); */
                   3361:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3362:       /*           printf("%f ",pmmij[i][j]); */
                   3363:       /*         } */
                   3364:       /*         printf(" oldm "); */
                   3365:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3366:       /*           printf("%f ",oldm[i][j]); */
                   3367:       /*         } */
                   3368:       /*         printf("\n"); */
                   3369:       /*       } */
                   3370:       /* } */
                   3371:       savm=oldm;
                   3372:       oldm=newm;
                   3373:     }
                   3374:     for(i=1; i<=nlstate+ndeath; i++)
                   3375:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3376:        po[i][j][h]=newm[i][j];
1.268     brouard  3377:        /* if(h==nhstepm) */
                   3378:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3379:       }
1.268     brouard  3380:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3381:   } /* end h */
1.268     brouard  3382:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3383:   return po;
                   3384: }
                   3385: 
                   3386: 
1.162     brouard  3387: #ifdef NLOPT
                   3388:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3389:   double fret;
                   3390:   double *xt;
                   3391:   int j;
                   3392:   myfunc_data *d2 = (myfunc_data *) pd;
                   3393: /* xt = (p1-1); */
                   3394:   xt=vector(1,n); 
                   3395:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3396: 
                   3397:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3398:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3399:   printf("Function = %.12lf ",fret);
                   3400:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3401:   printf("\n");
                   3402:  free_vector(xt,1,n);
                   3403:   return fret;
                   3404: }
                   3405: #endif
1.126     brouard  3406: 
                   3407: /*************** log-likelihood *************/
                   3408: double func( double *x)
                   3409: {
1.226     brouard  3410:   int i, ii, j, k, mi, d, kk;
                   3411:   int ioffset=0;
                   3412:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3413:   double **out;
                   3414:   double lli; /* Individual log likelihood */
                   3415:   int s1, s2;
1.228     brouard  3416:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3417:   double bbh, survp;
                   3418:   long ipmx;
                   3419:   double agexact;
                   3420:   /*extern weight */
                   3421:   /* We are differentiating ll according to initial status */
                   3422:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3423:   /*for(i=1;i<imx;i++) 
                   3424:     printf(" %d\n",s[4][i]);
                   3425:   */
1.162     brouard  3426: 
1.226     brouard  3427:   ++countcallfunc;
1.162     brouard  3428: 
1.226     brouard  3429:   cov[1]=1.;
1.126     brouard  3430: 
1.226     brouard  3431:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3432:   ioffset=0;
1.226     brouard  3433:   if(mle==1){
                   3434:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3435:       /* Computes the values of the ncovmodel covariates of the model
                   3436:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3437:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3438:         to be observed in j being in i according to the model.
                   3439:       */
1.243     brouard  3440:       ioffset=2+nagesqr ;
1.233     brouard  3441:    /* Fixed */
1.234     brouard  3442:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3443:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3444:       }
1.226     brouard  3445:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3446:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3447:         has been calculated etc */
                   3448:       /* For an individual i, wav[i] gives the number of effective waves */
                   3449:       /* We compute the contribution to Likelihood of each effective transition
                   3450:         mw[mi][i] is real wave of the mi th effectve wave */
                   3451:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3452:         s2=s[mw[mi+1][i]][i];
                   3453:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3454:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3455:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3456:       */
                   3457:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3458:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3459:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3460:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3461:        }
                   3462:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3463:          for (j=1;j<=nlstate+ndeath;j++){
                   3464:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3465:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3466:          }
                   3467:        for(d=0; d<dh[mi][i]; d++){
                   3468:          newm=savm;
                   3469:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3470:          cov[2]=agexact;
                   3471:          if(nagesqr==1)
                   3472:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3473:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3474:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3475:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3476:          else
                   3477:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3478:          }
                   3479:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3480:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3481:          savm=oldm;
                   3482:          oldm=newm;
                   3483:        } /* end mult */
                   3484:        
                   3485:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3486:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3487:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3488:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3489:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3490:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3491:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3492:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3493:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3494:                                 * -stepm/2 to stepm/2 .
                   3495:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3496:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3497:                                 */
1.234     brouard  3498:        s1=s[mw[mi][i]][i];
                   3499:        s2=s[mw[mi+1][i]][i];
                   3500:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3501:        /* bias bh is positive if real duration
                   3502:         * is higher than the multiple of stepm and negative otherwise.
                   3503:         */
                   3504:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3505:        if( s2 > nlstate){ 
                   3506:          /* i.e. if s2 is a death state and if the date of death is known 
                   3507:             then the contribution to the likelihood is the probability to 
                   3508:             die between last step unit time and current  step unit time, 
                   3509:             which is also equal to probability to die before dh 
                   3510:             minus probability to die before dh-stepm . 
                   3511:             In version up to 0.92 likelihood was computed
                   3512:             as if date of death was unknown. Death was treated as any other
                   3513:             health state: the date of the interview describes the actual state
                   3514:             and not the date of a change in health state. The former idea was
                   3515:             to consider that at each interview the state was recorded
                   3516:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3517:             introduced the exact date of death then we should have modified
                   3518:             the contribution of an exact death to the likelihood. This new
                   3519:             contribution is smaller and very dependent of the step unit
                   3520:             stepm. It is no more the probability to die between last interview
                   3521:             and month of death but the probability to survive from last
                   3522:             interview up to one month before death multiplied by the
                   3523:             probability to die within a month. Thanks to Chris
                   3524:             Jackson for correcting this bug.  Former versions increased
                   3525:             mortality artificially. The bad side is that we add another loop
                   3526:             which slows down the processing. The difference can be up to 10%
                   3527:             lower mortality.
                   3528:          */
                   3529:          /* If, at the beginning of the maximization mostly, the
                   3530:             cumulative probability or probability to be dead is
                   3531:             constant (ie = 1) over time d, the difference is equal to
                   3532:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3533:             s1 at precedent wave, to be dead a month before current
                   3534:             wave is equal to probability, being at state s1 at
                   3535:             precedent wave, to be dead at mont of the current
                   3536:             wave. Then the observed probability (that this person died)
                   3537:             is null according to current estimated parameter. In fact,
                   3538:             it should be very low but not zero otherwise the log go to
                   3539:             infinity.
                   3540:          */
1.183     brouard  3541: /* #ifdef INFINITYORIGINAL */
                   3542: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3543: /* #else */
                   3544: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3545: /*         lli=log(mytinydouble); */
                   3546: /*       else */
                   3547: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3548: /* #endif */
1.226     brouard  3549:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3550:          
1.226     brouard  3551:        } else if  ( s2==-1 ) { /* alive */
                   3552:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3553:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3554:          /*survp += out[s1][j]; */
                   3555:          lli= log(survp);
                   3556:        }
                   3557:        else if  (s2==-4) { 
                   3558:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3559:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3560:          lli= log(survp); 
                   3561:        } 
                   3562:        else if  (s2==-5) { 
                   3563:          for (j=1,survp=0. ; j<=2; j++)  
                   3564:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3565:          lli= log(survp); 
                   3566:        } 
                   3567:        else{
                   3568:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3569:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3570:        } 
                   3571:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3572:        /*if(lli ==000.0)*/
                   3573:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3574:        ipmx +=1;
                   3575:        sw += weight[i];
                   3576:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3577:        /* if (lli < log(mytinydouble)){ */
                   3578:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3579:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3580:        /* } */
                   3581:       } /* end of wave */
                   3582:     } /* end of individual */
                   3583:   }  else if(mle==2){
                   3584:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3585:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3586:       for(mi=1; mi<= wav[i]-1; mi++){
                   3587:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3588:          for (j=1;j<=nlstate+ndeath;j++){
                   3589:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3590:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3591:          }
                   3592:        for(d=0; d<=dh[mi][i]; d++){
                   3593:          newm=savm;
                   3594:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3595:          cov[2]=agexact;
                   3596:          if(nagesqr==1)
                   3597:            cov[3]= agexact*agexact;
                   3598:          for (kk=1; kk<=cptcovage;kk++) {
                   3599:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3600:          }
                   3601:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3602:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3603:          savm=oldm;
                   3604:          oldm=newm;
                   3605:        } /* end mult */
                   3606:       
                   3607:        s1=s[mw[mi][i]][i];
                   3608:        s2=s[mw[mi+1][i]][i];
                   3609:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3610:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3611:        ipmx +=1;
                   3612:        sw += weight[i];
                   3613:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3614:       } /* end of wave */
                   3615:     } /* end of individual */
                   3616:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3617:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3618:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3619:       for(mi=1; mi<= wav[i]-1; mi++){
                   3620:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3621:          for (j=1;j<=nlstate+ndeath;j++){
                   3622:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3623:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3624:          }
                   3625:        for(d=0; d<dh[mi][i]; d++){
                   3626:          newm=savm;
                   3627:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3628:          cov[2]=agexact;
                   3629:          if(nagesqr==1)
                   3630:            cov[3]= agexact*agexact;
                   3631:          for (kk=1; kk<=cptcovage;kk++) {
                   3632:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3633:          }
                   3634:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3635:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3636:          savm=oldm;
                   3637:          oldm=newm;
                   3638:        } /* end mult */
                   3639:       
                   3640:        s1=s[mw[mi][i]][i];
                   3641:        s2=s[mw[mi+1][i]][i];
                   3642:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3643:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3644:        ipmx +=1;
                   3645:        sw += weight[i];
                   3646:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3647:       } /* end of wave */
                   3648:     } /* end of individual */
                   3649:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3650:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3651:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3652:       for(mi=1; mi<= wav[i]-1; mi++){
                   3653:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3654:          for (j=1;j<=nlstate+ndeath;j++){
                   3655:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3656:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3657:          }
                   3658:        for(d=0; d<dh[mi][i]; d++){
                   3659:          newm=savm;
                   3660:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3661:          cov[2]=agexact;
                   3662:          if(nagesqr==1)
                   3663:            cov[3]= agexact*agexact;
                   3664:          for (kk=1; kk<=cptcovage;kk++) {
                   3665:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3666:          }
1.126     brouard  3667:        
1.226     brouard  3668:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3669:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3670:          savm=oldm;
                   3671:          oldm=newm;
                   3672:        } /* end mult */
                   3673:       
                   3674:        s1=s[mw[mi][i]][i];
                   3675:        s2=s[mw[mi+1][i]][i];
                   3676:        if( s2 > nlstate){ 
                   3677:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3678:        } else if  ( s2==-1 ) { /* alive */
                   3679:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3680:            survp += out[s1][j];
                   3681:          lli= log(survp);
                   3682:        }else{
                   3683:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3684:        }
                   3685:        ipmx +=1;
                   3686:        sw += weight[i];
                   3687:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3688: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3689:       } /* end of wave */
                   3690:     } /* end of individual */
                   3691:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3692:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3693:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3694:       for(mi=1; mi<= wav[i]-1; mi++){
                   3695:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3696:          for (j=1;j<=nlstate+ndeath;j++){
                   3697:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3698:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3699:          }
                   3700:        for(d=0; d<dh[mi][i]; d++){
                   3701:          newm=savm;
                   3702:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3703:          cov[2]=agexact;
                   3704:          if(nagesqr==1)
                   3705:            cov[3]= agexact*agexact;
                   3706:          for (kk=1; kk<=cptcovage;kk++) {
                   3707:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3708:          }
1.126     brouard  3709:        
1.226     brouard  3710:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3711:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3712:          savm=oldm;
                   3713:          oldm=newm;
                   3714:        } /* end mult */
                   3715:       
                   3716:        s1=s[mw[mi][i]][i];
                   3717:        s2=s[mw[mi+1][i]][i];
                   3718:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3719:        ipmx +=1;
                   3720:        sw += weight[i];
                   3721:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3722:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3723:       } /* end of wave */
                   3724:     } /* end of individual */
                   3725:   } /* End of if */
                   3726:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3727:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3728:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3729:   return -l;
1.126     brouard  3730: }
                   3731: 
                   3732: /*************** log-likelihood *************/
                   3733: double funcone( double *x)
                   3734: {
1.228     brouard  3735:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3736:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3737:   int ioffset=0;
1.131     brouard  3738:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3739:   double **out;
                   3740:   double lli; /* Individual log likelihood */
                   3741:   double llt;
                   3742:   int s1, s2;
1.228     brouard  3743:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3744: 
1.126     brouard  3745:   double bbh, survp;
1.187     brouard  3746:   double agexact;
1.214     brouard  3747:   double agebegin, ageend;
1.126     brouard  3748:   /*extern weight */
                   3749:   /* We are differentiating ll according to initial status */
                   3750:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3751:   /*for(i=1;i<imx;i++) 
                   3752:     printf(" %d\n",s[4][i]);
                   3753:   */
                   3754:   cov[1]=1.;
                   3755: 
                   3756:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3757:   ioffset=0;
                   3758:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3759:     /* ioffset=2+nagesqr+cptcovage; */
                   3760:     ioffset=2+nagesqr;
1.232     brouard  3761:     /* Fixed */
1.224     brouard  3762:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3763:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3764:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3765:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3766: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3767: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3768: /*    cov[2+6]=covar[2][i]; V2  */
                   3769: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3770: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3771: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3772: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3773: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3774: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3775:     }
1.232     brouard  3776:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3777:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3778:     /* } */
1.231     brouard  3779:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3780:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3781:     /* } */
1.225     brouard  3782:     
1.233     brouard  3783: 
                   3784:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3785:     /* Wave varying (but not age varying) */
                   3786:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3787:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3788:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3789:       }
1.232     brouard  3790:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3791:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3792:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3793:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3794:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3795:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3796:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3797:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3798:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3799:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3800:       /* } */
1.126     brouard  3801:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3802:        for (j=1;j<=nlstate+ndeath;j++){
                   3803:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3804:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3805:        }
1.214     brouard  3806:       
                   3807:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3808:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3809:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3810:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3811:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3812:          and mw[mi+1][i]. dh depends on stepm.*/
                   3813:        newm=savm;
1.247     brouard  3814:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3815:        cov[2]=agexact;
                   3816:        if(nagesqr==1)
                   3817:          cov[3]= agexact*agexact;
                   3818:        for (kk=1; kk<=cptcovage;kk++) {
                   3819:          if(!FixedV[Tvar[Tage[kk]]])
                   3820:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3821:          else
                   3822:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3823:        }
                   3824:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3825:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3826:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3827:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3828:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3829:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3830:        savm=oldm;
                   3831:        oldm=newm;
1.126     brouard  3832:       } /* end mult */
                   3833:       
                   3834:       s1=s[mw[mi][i]][i];
                   3835:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3836:       /* if(s2==-1){ */
1.268     brouard  3837:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3838:       /*       /\* exit(1); *\/ */
                   3839:       /* } */
1.126     brouard  3840:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3841:       /* bias is positive if real duration
                   3842:        * is higher than the multiple of stepm and negative otherwise.
                   3843:        */
                   3844:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3845:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3846:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3847:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3848:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3849:        lli= log(survp);
1.126     brouard  3850:       }else if (mle==1){
1.242     brouard  3851:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3852:       } else if(mle==2){
1.242     brouard  3853:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3854:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3855:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3856:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3857:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3858:       } else{  /* mle=0 back to 1 */
1.242     brouard  3859:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3860:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3861:       } /* End of if */
                   3862:       ipmx +=1;
                   3863:       sw += weight[i];
                   3864:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3865:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3866:       if(globpr){
1.246     brouard  3867:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3868:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3869:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3870:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3871:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3872:          llt +=ll[k]*gipmx/gsw;
                   3873:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3874:        }
                   3875:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3876:       }
1.232     brouard  3877:        } /* end of wave */
                   3878: } /* end of individual */
                   3879: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3880: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3881: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3882: if(globpr==0){ /* First time we count the contributions and weights */
                   3883:        gipmx=ipmx;
                   3884:        gsw=sw;
                   3885: }
                   3886: return -l;
1.126     brouard  3887: }
                   3888: 
                   3889: 
                   3890: /*************** function likelione ***********/
                   3891: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
                   3892: {
                   3893:   /* This routine should help understanding what is done with 
                   3894:      the selection of individuals/waves and
                   3895:      to check the exact contribution to the likelihood.
                   3896:      Plotting could be done.
                   3897:    */
                   3898:   int k;
                   3899: 
                   3900:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3901:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3902:     strcat(fileresilk,fileresu);
1.126     brouard  3903:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3904:       printf("Problem with resultfile: %s\n", fileresilk);
                   3905:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3906:     }
1.214     brouard  3907:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3908:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3909:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3910:     for(k=1; k<=nlstate; k++) 
                   3911:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3912:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3913:   }
                   3914: 
                   3915:   *fretone=(*funcone)(p);
                   3916:   if(*globpri !=0){
                   3917:     fclose(ficresilk);
1.205     brouard  3918:     if (mle ==0)
                   3919:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3920:     else if(mle >=1)
                   3921:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3922:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3923:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3924:       
                   3925:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3926:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3927: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3928:     }
1.207     brouard  3929:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3930: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3931:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3932: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3933:     fflush(fichtm);
1.205     brouard  3934:   }
1.126     brouard  3935:   return;
                   3936: }
                   3937: 
                   3938: 
                   3939: /*********** Maximum Likelihood Estimation ***************/
                   3940: 
                   3941: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3942: {
1.165     brouard  3943:   int i,j, iter=0;
1.126     brouard  3944:   double **xi;
                   3945:   double fret;
                   3946:   double fretone; /* Only one call to likelihood */
                   3947:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3948: 
                   3949: #ifdef NLOPT
                   3950:   int creturn;
                   3951:   nlopt_opt opt;
                   3952:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3953:   double *lb;
                   3954:   double minf; /* the minimum objective value, upon return */
                   3955:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3956:   myfunc_data dinst, *d = &dinst;
                   3957: #endif
                   3958: 
                   3959: 
1.126     brouard  3960:   xi=matrix(1,npar,1,npar);
                   3961:   for (i=1;i<=npar;i++)
                   3962:     for (j=1;j<=npar;j++)
                   3963:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3964:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3965:   strcpy(filerespow,"POW_"); 
1.126     brouard  3966:   strcat(filerespow,fileres);
                   3967:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3968:     printf("Problem with resultfile: %s\n", filerespow);
                   3969:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3970:   }
                   3971:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3972:   for (i=1;i<=nlstate;i++)
                   3973:     for(j=1;j<=nlstate+ndeath;j++)
                   3974:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3975:   fprintf(ficrespow,"\n");
1.162     brouard  3976: #ifdef POWELL
1.126     brouard  3977:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3978: #endif
1.126     brouard  3979: 
1.162     brouard  3980: #ifdef NLOPT
                   3981: #ifdef NEWUOA
                   3982:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3983: #else
                   3984:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3985: #endif
                   3986:   lb=vector(0,npar-1);
                   3987:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3988:   nlopt_set_lower_bounds(opt, lb);
                   3989:   nlopt_set_initial_step1(opt, 0.1);
                   3990:   
                   3991:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3992:   d->function = func;
                   3993:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3994:   nlopt_set_min_objective(opt, myfunc, d);
                   3995:   nlopt_set_xtol_rel(opt, ftol);
                   3996:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   3997:     printf("nlopt failed! %d\n",creturn); 
                   3998:   }
                   3999:   else {
                   4000:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4001:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4002:     iter=1; /* not equal */
                   4003:   }
                   4004:   nlopt_destroy(opt);
                   4005: #endif
1.126     brouard  4006:   free_matrix(xi,1,npar,1,npar);
                   4007:   fclose(ficrespow);
1.203     brouard  4008:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4009:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4010:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4011: 
                   4012: }
                   4013: 
                   4014: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4015: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4016: {
                   4017:   double  **a,**y,*x,pd;
1.203     brouard  4018:   /* double **hess; */
1.164     brouard  4019:   int i, j;
1.126     brouard  4020:   int *indx;
                   4021: 
                   4022:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4023:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4024:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4025:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4026:   double gompertz(double p[]);
1.203     brouard  4027:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4028: 
                   4029:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4030:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4031:   for (i=1;i<=npar;i++){
1.203     brouard  4032:     printf("%d-",i);fflush(stdout);
                   4033:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4034:    
                   4035:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4036:     
                   4037:     /*  printf(" %f ",p[i]);
                   4038:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4039:   }
                   4040:   
                   4041:   for (i=1;i<=npar;i++) {
                   4042:     for (j=1;j<=npar;j++)  {
                   4043:       if (j>i) { 
1.203     brouard  4044:        printf(".%d-%d",i,j);fflush(stdout);
                   4045:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4046:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4047:        
                   4048:        hess[j][i]=hess[i][j];    
                   4049:        /*printf(" %lf ",hess[i][j]);*/
                   4050:       }
                   4051:     }
                   4052:   }
                   4053:   printf("\n");
                   4054:   fprintf(ficlog,"\n");
                   4055: 
                   4056:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4057:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4058:   
                   4059:   a=matrix(1,npar,1,npar);
                   4060:   y=matrix(1,npar,1,npar);
                   4061:   x=vector(1,npar);
                   4062:   indx=ivector(1,npar);
                   4063:   for (i=1;i<=npar;i++)
                   4064:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4065:   ludcmp(a,npar,indx,&pd);
                   4066: 
                   4067:   for (j=1;j<=npar;j++) {
                   4068:     for (i=1;i<=npar;i++) x[i]=0;
                   4069:     x[j]=1;
                   4070:     lubksb(a,npar,indx,x);
                   4071:     for (i=1;i<=npar;i++){ 
                   4072:       matcov[i][j]=x[i];
                   4073:     }
                   4074:   }
                   4075: 
                   4076:   printf("\n#Hessian matrix#\n");
                   4077:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4078:   for (i=1;i<=npar;i++) { 
                   4079:     for (j=1;j<=npar;j++) { 
1.203     brouard  4080:       printf("%.6e ",hess[i][j]);
                   4081:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4082:     }
                   4083:     printf("\n");
                   4084:     fprintf(ficlog,"\n");
                   4085:   }
                   4086: 
1.203     brouard  4087:   /* printf("\n#Covariance matrix#\n"); */
                   4088:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4089:   /* for (i=1;i<=npar;i++) {  */
                   4090:   /*   for (j=1;j<=npar;j++) {  */
                   4091:   /*     printf("%.6e ",matcov[i][j]); */
                   4092:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4093:   /*   } */
                   4094:   /*   printf("\n"); */
                   4095:   /*   fprintf(ficlog,"\n"); */
                   4096:   /* } */
                   4097: 
1.126     brouard  4098:   /* Recompute Inverse */
1.203     brouard  4099:   /* for (i=1;i<=npar;i++) */
                   4100:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4101:   /* ludcmp(a,npar,indx,&pd); */
                   4102: 
                   4103:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4104: 
                   4105:   /* for (j=1;j<=npar;j++) { */
                   4106:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4107:   /*   x[j]=1; */
                   4108:   /*   lubksb(a,npar,indx,x); */
                   4109:   /*   for (i=1;i<=npar;i++){  */
                   4110:   /*     y[i][j]=x[i]; */
                   4111:   /*     printf("%.3e ",y[i][j]); */
                   4112:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4113:   /*   } */
                   4114:   /*   printf("\n"); */
                   4115:   /*   fprintf(ficlog,"\n"); */
                   4116:   /* } */
                   4117: 
                   4118:   /* Verifying the inverse matrix */
                   4119: #ifdef DEBUGHESS
                   4120:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4121: 
1.203     brouard  4122:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4123:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4124: 
                   4125:   for (j=1;j<=npar;j++) {
                   4126:     for (i=1;i<=npar;i++){ 
1.203     brouard  4127:       printf("%.2f ",y[i][j]);
                   4128:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4129:     }
                   4130:     printf("\n");
                   4131:     fprintf(ficlog,"\n");
                   4132:   }
1.203     brouard  4133: #endif
1.126     brouard  4134: 
                   4135:   free_matrix(a,1,npar,1,npar);
                   4136:   free_matrix(y,1,npar,1,npar);
                   4137:   free_vector(x,1,npar);
                   4138:   free_ivector(indx,1,npar);
1.203     brouard  4139:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4140: 
                   4141: 
                   4142: }
                   4143: 
                   4144: /*************** hessian matrix ****************/
                   4145: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4146: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4147:   int i;
                   4148:   int l=1, lmax=20;
1.203     brouard  4149:   double k1,k2, res, fx;
1.132     brouard  4150:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4151:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4152:   int k=0,kmax=10;
                   4153:   double l1;
                   4154: 
                   4155:   fx=func(x);
                   4156:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4157:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4158:     l1=pow(10,l);
                   4159:     delts=delt;
                   4160:     for(k=1 ; k <kmax; k=k+1){
                   4161:       delt = delta*(l1*k);
                   4162:       p2[theta]=x[theta] +delt;
1.145     brouard  4163:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4164:       p2[theta]=x[theta]-delt;
                   4165:       k2=func(p2)-fx;
                   4166:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4167:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4168:       
1.203     brouard  4169: #ifdef DEBUGHESSII
1.126     brouard  4170:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4171:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4172: #endif
                   4173:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4174:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4175:        k=kmax;
                   4176:       }
                   4177:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4178:        k=kmax; l=lmax*10;
1.126     brouard  4179:       }
                   4180:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4181:        delts=delt;
                   4182:       }
1.203     brouard  4183:     } /* End loop k */
1.126     brouard  4184:   }
                   4185:   delti[theta]=delts;
                   4186:   return res; 
                   4187:   
                   4188: }
                   4189: 
1.203     brouard  4190: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4191: {
                   4192:   int i;
1.164     brouard  4193:   int l=1, lmax=20;
1.126     brouard  4194:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4195:   double p2[MAXPARM+1];
1.203     brouard  4196:   int k, kmax=1;
                   4197:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4198: 
                   4199:   int firstime=0;
1.203     brouard  4200:   
1.126     brouard  4201:   fx=func(x);
1.203     brouard  4202:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4203:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4204:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4205:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4206:     k1=func(p2)-fx;
                   4207:   
1.203     brouard  4208:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4209:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4210:     k2=func(p2)-fx;
                   4211:   
1.203     brouard  4212:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4213:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4214:     k3=func(p2)-fx;
                   4215:   
1.203     brouard  4216:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4217:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4218:     k4=func(p2)-fx;
1.203     brouard  4219:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4220:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4221:       firstime=1;
1.203     brouard  4222:       kmax=kmax+10;
1.208     brouard  4223:     }
                   4224:     if(kmax >=10 || firstime ==1){
1.246     brouard  4225:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4226:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4227:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4228:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4229:     }
                   4230: #ifdef DEBUGHESSIJ
                   4231:     v1=hess[thetai][thetai];
                   4232:     v2=hess[thetaj][thetaj];
                   4233:     cv12=res;
                   4234:     /* Computing eigen value of Hessian matrix */
                   4235:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4236:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4237:     if ((lc2 <0) || (lc1 <0) ){
                   4238:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4239:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4240:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4241:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4242:     }
1.126     brouard  4243: #endif
                   4244:   }
                   4245:   return res;
                   4246: }
                   4247: 
1.203     brouard  4248:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4249: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4250: /* { */
                   4251: /*   int i; */
                   4252: /*   int l=1, lmax=20; */
                   4253: /*   double k1,k2,k3,k4,res,fx; */
                   4254: /*   double p2[MAXPARM+1]; */
                   4255: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4256: /*   int k=0,kmax=10; */
                   4257: /*   double l1; */
                   4258:   
                   4259: /*   fx=func(x); */
                   4260: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4261: /*     l1=pow(10,l); */
                   4262: /*     delts=delt; */
                   4263: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4264: /*       delt = delti*(l1*k); */
                   4265: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4266: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4267: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4268: /*       k1=func(p2)-fx; */
                   4269:       
                   4270: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4271: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4272: /*       k2=func(p2)-fx; */
                   4273:       
                   4274: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4275: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4276: /*       k3=func(p2)-fx; */
                   4277:       
                   4278: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4279: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4280: /*       k4=func(p2)-fx; */
                   4281: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4282: /* #ifdef DEBUGHESSIJ */
                   4283: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4284: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4285: /* #endif */
                   4286: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4287: /*     k=kmax; */
                   4288: /*       } */
                   4289: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4290: /*     k=kmax; l=lmax*10; */
                   4291: /*       } */
                   4292: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4293: /*     delts=delt; */
                   4294: /*       } */
                   4295: /*     } /\* End loop k *\/ */
                   4296: /*   } */
                   4297: /*   delti[theta]=delts; */
                   4298: /*   return res;  */
                   4299: /* } */
                   4300: 
                   4301: 
1.126     brouard  4302: /************** Inverse of matrix **************/
                   4303: void ludcmp(double **a, int n, int *indx, double *d) 
                   4304: { 
                   4305:   int i,imax,j,k; 
                   4306:   double big,dum,sum,temp; 
                   4307:   double *vv; 
                   4308:  
                   4309:   vv=vector(1,n); 
                   4310:   *d=1.0; 
                   4311:   for (i=1;i<=n;i++) { 
                   4312:     big=0.0; 
                   4313:     for (j=1;j<=n;j++) 
                   4314:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4315:     if (big == 0.0){
                   4316:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4317:       for (j=1;j<=n;j++) {
                   4318:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4319:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4320:       }
                   4321:       fflush(ficlog);
                   4322:       fclose(ficlog);
                   4323:       nrerror("Singular matrix in routine ludcmp"); 
                   4324:     }
1.126     brouard  4325:     vv[i]=1.0/big; 
                   4326:   } 
                   4327:   for (j=1;j<=n;j++) { 
                   4328:     for (i=1;i<j;i++) { 
                   4329:       sum=a[i][j]; 
                   4330:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4331:       a[i][j]=sum; 
                   4332:     } 
                   4333:     big=0.0; 
                   4334:     for (i=j;i<=n;i++) { 
                   4335:       sum=a[i][j]; 
                   4336:       for (k=1;k<j;k++) 
                   4337:        sum -= a[i][k]*a[k][j]; 
                   4338:       a[i][j]=sum; 
                   4339:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4340:        big=dum; 
                   4341:        imax=i; 
                   4342:       } 
                   4343:     } 
                   4344:     if (j != imax) { 
                   4345:       for (k=1;k<=n;k++) { 
                   4346:        dum=a[imax][k]; 
                   4347:        a[imax][k]=a[j][k]; 
                   4348:        a[j][k]=dum; 
                   4349:       } 
                   4350:       *d = -(*d); 
                   4351:       vv[imax]=vv[j]; 
                   4352:     } 
                   4353:     indx[j]=imax; 
                   4354:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4355:     if (j != n) { 
                   4356:       dum=1.0/(a[j][j]); 
                   4357:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4358:     } 
                   4359:   } 
                   4360:   free_vector(vv,1,n);  /* Doesn't work */
                   4361: ;
                   4362: } 
                   4363: 
                   4364: void lubksb(double **a, int n, int *indx, double b[]) 
                   4365: { 
                   4366:   int i,ii=0,ip,j; 
                   4367:   double sum; 
                   4368:  
                   4369:   for (i=1;i<=n;i++) { 
                   4370:     ip=indx[i]; 
                   4371:     sum=b[ip]; 
                   4372:     b[ip]=b[i]; 
                   4373:     if (ii) 
                   4374:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4375:     else if (sum) ii=i; 
                   4376:     b[i]=sum; 
                   4377:   } 
                   4378:   for (i=n;i>=1;i--) { 
                   4379:     sum=b[i]; 
                   4380:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4381:     b[i]=sum/a[i][i]; 
                   4382:   } 
                   4383: } 
                   4384: 
                   4385: void pstamp(FILE *fichier)
                   4386: {
1.196     brouard  4387:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4388: }
                   4389: 
1.253     brouard  4390: 
                   4391: 
1.126     brouard  4392: /************ Frequencies ********************/
1.251     brouard  4393: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4394:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4395:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4396: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4397:   
1.265     brouard  4398:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4399:   int iind=0, iage=0;
                   4400:   int mi; /* Effective wave */
                   4401:   int first;
                   4402:   double ***freq; /* Frequencies */
1.268     brouard  4403:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4404:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4405:   double *meanq, *stdq, *idq;
1.226     brouard  4406:   double **meanqt;
                   4407:   double *pp, **prop, *posprop, *pospropt;
                   4408:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4409:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4410:   double agebegin, ageend;
                   4411:     
                   4412:   pp=vector(1,nlstate);
1.251     brouard  4413:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4414:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4415:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4416:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4417:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4418:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4419:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4420:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4421:   strcpy(fileresp,"P_");
                   4422:   strcat(fileresp,fileresu);
                   4423:   /*strcat(fileresphtm,fileresu);*/
                   4424:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4425:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4426:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4427:     exit(0);
                   4428:   }
1.240     brouard  4429:   
1.226     brouard  4430:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4431:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4432:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4433:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4434:     fflush(ficlog);
                   4435:     exit(70); 
                   4436:   }
                   4437:   else{
                   4438:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4439: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4440: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4441:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4442:   }
1.237     brouard  4443:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4444:   
1.226     brouard  4445:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4446:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4447:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4448:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4449:     fflush(ficlog);
                   4450:     exit(70); 
1.240     brouard  4451:   } else{
1.226     brouard  4452:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4453: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4454: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4455:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4456:   }
1.240     brouard  4457:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4458:   
1.253     brouard  4459:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4460:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4461:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4462:   j1=0;
1.126     brouard  4463:   
1.227     brouard  4464:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4465:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4466:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4467:   
                   4468:   
1.226     brouard  4469:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4470:      reference=low_education V1=0,V2=0
                   4471:      med_educ                V1=1 V2=0, 
                   4472:      high_educ               V1=0 V2=1
                   4473:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4474:   */
1.249     brouard  4475:   dateintsum=0;
                   4476:   k2cpt=0;
                   4477: 
1.253     brouard  4478:   if(cptcoveff == 0 )
1.265     brouard  4479:     nl=1;  /* Constant and age model only */
1.253     brouard  4480:   else
                   4481:     nl=2;
1.265     brouard  4482: 
                   4483:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4484:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4485:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4486:    *     freq[s1][s2][iage] =0.
                   4487:    *     Loop on iind
                   4488:    *       ++freq[s1][s2][iage] weighted
                   4489:    *     end iind
                   4490:    *     if covariate and j!0
                   4491:    *       headers Variable on one line
                   4492:    *     endif cov j!=0
                   4493:    *     header of frequency table by age
                   4494:    *     Loop on age
                   4495:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4496:    *       pos+=freq[s1][s2][iage] weighted
                   4497:    *       Loop on s1 initial state
                   4498:    *         fprintf(ficresp
                   4499:    *       end s1
                   4500:    *     end age
                   4501:    *     if j!=0 computes starting values
                   4502:    *     end compute starting values
                   4503:    *   end j1
                   4504:    * end nl 
                   4505:    */
1.253     brouard  4506:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4507:     if(nj==1)
                   4508:       j=0;  /* First pass for the constant */
1.265     brouard  4509:     else{
1.253     brouard  4510:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4511:     }
1.251     brouard  4512:     first=1;
1.265     brouard  4513:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4514:       posproptt=0.;
                   4515:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4516:        scanf("%d", i);*/
                   4517:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4518:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4519:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4520:            freq[i][s2][m]=0;
1.251     brouard  4521:       
                   4522:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4523:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4524:          prop[i][m]=0;
                   4525:        posprop[i]=0;
                   4526:        pospropt[i]=0;
                   4527:       }
1.283     brouard  4528:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4529:         idq[z1]=0.;
                   4530:         meanq[z1]=0.;
                   4531:         stdq[z1]=0.;
1.283     brouard  4532:       }
                   4533:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4534:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4535:       /*         meanqt[m][z1]=0.; */
                   4536:       /*       } */
                   4537:       /* }       */
1.251     brouard  4538:       /* dateintsum=0; */
                   4539:       /* k2cpt=0; */
                   4540:       
1.265     brouard  4541:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4542:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4543:        bool=1;
                   4544:        if(j !=0){
                   4545:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4546:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4547:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4548:                /* if(Tvaraff[z1] ==-20){ */
                   4549:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4550:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4551:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4552:                /* }else  */
                   4553:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4554:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4555:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4556:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4557:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4558:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4559:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4560:                } /* Onlyf fixed */
                   4561:              } /* end z1 */
                   4562:            } /* cptcovn > 0 */
                   4563:          } /* end any */
                   4564:        }/* end j==0 */
1.265     brouard  4565:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4566:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4567:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4568:            m=mw[mi][iind];
                   4569:            if(j!=0){
                   4570:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4571:                for (z1=1; z1<=cptcoveff; z1++) {
                   4572:                  if( Fixed[Tmodelind[z1]]==1){
                   4573:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4574:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4575:                                                                                      value is -1, we don't select. It differs from the 
                   4576:                                                                                      constant and age model which counts them. */
                   4577:                      bool=0; /* not selected */
                   4578:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4579:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4580:                      bool=0;
                   4581:                    }
                   4582:                  }
                   4583:                }
                   4584:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4585:            } /* end j==0 */
                   4586:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4587:            if(bool==1){ /*Selected */
1.251     brouard  4588:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4589:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4590:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4591:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4592:              if(m >=firstpass && m <=lastpass){
                   4593:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4594:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4595:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4596:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4597:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4598:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4599:                if (m<lastpass) {
                   4600:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4601:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4602:                  if(s[m][iind]==-1)
                   4603:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4604:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.284     brouard  4605:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean */
                   4606:                    idq[z1]=idq[z1]+weight[iind];
                   4607:                    meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4608:                    stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4609:                  }
1.251     brouard  4610:                  /* if((int)agev[m][iind] == 55) */
                   4611:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4612:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4613:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4614:                }
1.251     brouard  4615:              } /* end if between passes */  
                   4616:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4617:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4618:                k2cpt++;
                   4619:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4620:              }
1.251     brouard  4621:            }else{
                   4622:              bool=1;
                   4623:            }/* end bool 2 */
                   4624:          } /* end m */
1.284     brouard  4625:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4626:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4627:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4628:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4629:          /* } */
1.251     brouard  4630:        } /* end bool */
                   4631:       } /* end iind = 1 to imx */
                   4632:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4633:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4634:       
                   4635:       
                   4636:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4637:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4638:         pstamp(ficresp);
1.251     brouard  4639:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4640:         pstamp(ficresp);
1.251     brouard  4641:        printf( "\n#********** Variable "); 
                   4642:        fprintf(ficresp, "\n#********** Variable "); 
                   4643:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4644:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4645:        fprintf(ficlog, "\n#********** Variable "); 
                   4646:        for (z1=1; z1<=cptcoveff; z1++){
                   4647:          if(!FixedV[Tvaraff[z1]]){
                   4648:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4649:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4650:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4651:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4652:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4653:          }else{
1.251     brouard  4654:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4655:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4656:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4657:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4658:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4659:          }
                   4660:        }
                   4661:        printf( "**********\n#");
                   4662:        fprintf(ficresp, "**********\n#");
                   4663:        fprintf(ficresphtm, "**********</h3>\n");
                   4664:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4665:        fprintf(ficlog, "**********\n");
                   4666:       }
1.284     brouard  4667:       /*
                   4668:        Printing means of quantitative variables if any
                   4669:       */
                   4670:       for (z1=1; z1<= nqfveff; z1++) {
1.285     brouard  4671:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.0f individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.284     brouard  4672:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
                   4673:        if(weightopt==1){
                   4674:          printf(" Weighted mean and standard deviation of");
                   4675:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4676:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4677:        }
1.285     brouard  4678:        printf(" fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4679:        fprintf(ficlog," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4680:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
1.284     brouard  4681:       }
                   4682:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4683:       /*       for(m=1;m<=lastpass;m++){ */
                   4684:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4685:       /*   } */
                   4686:       /* } */
1.283     brouard  4687: 
1.251     brouard  4688:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4689:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4690:         fprintf(ficresp, " Age");
                   4691:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4692:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4693:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4694:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4695:       }
1.265     brouard  4696:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4697:       fprintf(ficresphtm, "\n");
                   4698:       
                   4699:       /* Header of frequency table by age */
                   4700:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4701:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4702:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4703:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4704:          if(s2!=0 && m!=0)
                   4705:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4706:        }
1.226     brouard  4707:       }
1.251     brouard  4708:       fprintf(ficresphtmfr, "\n");
                   4709:     
                   4710:       /* For each age */
                   4711:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4712:        fprintf(ficresphtm,"<tr>");
                   4713:        if(iage==iagemax+1){
                   4714:          fprintf(ficlog,"1");
                   4715:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4716:        }else if(iage==iagemax+2){
                   4717:          fprintf(ficlog,"0");
                   4718:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4719:        }else if(iage==iagemax+3){
                   4720:          fprintf(ficlog,"Total");
                   4721:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4722:        }else{
1.240     brouard  4723:          if(first==1){
1.251     brouard  4724:            first=0;
                   4725:            printf("See log file for details...\n");
                   4726:          }
                   4727:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4728:          fprintf(ficlog,"Age %d", iage);
                   4729:        }
1.265     brouard  4730:        for(s1=1; s1 <=nlstate ; s1++){
                   4731:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4732:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4733:        }
1.265     brouard  4734:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4735:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4736:            pos += freq[s1][m][iage];
                   4737:          if(pp[s1]>=1.e-10){
1.251     brouard  4738:            if(first==1){
1.265     brouard  4739:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4740:            }
1.265     brouard  4741:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4742:          }else{
                   4743:            if(first==1)
1.265     brouard  4744:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4745:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4746:          }
                   4747:        }
                   4748:       
1.265     brouard  4749:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4750:          /* posprop[s1]=0; */
                   4751:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4752:            pp[s1] += freq[s1][m][iage];
                   4753:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4754:       
                   4755:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4756:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4757:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4758:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4759:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4760:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4761:        }
                   4762:        
                   4763:        /* Writing ficresp */
                   4764:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4765:           if( iage <= iagemax){
                   4766:            fprintf(ficresp," %d",iage);
                   4767:           }
                   4768:         }else if( nj==2){
                   4769:           if( iage <= iagemax){
                   4770:            fprintf(ficresp," %d",iage);
                   4771:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4772:           }
1.240     brouard  4773:        }
1.265     brouard  4774:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4775:          if(pos>=1.e-5){
1.251     brouard  4776:            if(first==1)
1.265     brouard  4777:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4778:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4779:          }else{
                   4780:            if(first==1)
1.265     brouard  4781:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4782:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4783:          }
                   4784:          if( iage <= iagemax){
                   4785:            if(pos>=1.e-5){
1.265     brouard  4786:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4787:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4788:               }else if( nj==2){
                   4789:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4790:               }
                   4791:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4792:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4793:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4794:            } else{
                   4795:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4796:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4797:            }
1.240     brouard  4798:          }
1.265     brouard  4799:          pospropt[s1] +=posprop[s1];
                   4800:        } /* end loop s1 */
1.251     brouard  4801:        /* pospropt=0.; */
1.265     brouard  4802:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4803:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4804:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4805:              if(first==1){
1.265     brouard  4806:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4807:              }
1.265     brouard  4808:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4809:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4810:            }
1.265     brouard  4811:            if(s1!=0 && m!=0)
                   4812:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4813:          }
1.265     brouard  4814:        } /* end loop s1 */
1.251     brouard  4815:        posproptt=0.; 
1.265     brouard  4816:        for(s1=1; s1 <=nlstate; s1++){
                   4817:          posproptt += pospropt[s1];
1.251     brouard  4818:        }
                   4819:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4820:        fprintf(ficresphtm,"</tr>\n");
                   4821:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4822:          if(iage <= iagemax)
                   4823:            fprintf(ficresp,"\n");
1.240     brouard  4824:        }
1.251     brouard  4825:        if(first==1)
                   4826:          printf("Others in log...\n");
                   4827:        fprintf(ficlog,"\n");
                   4828:       } /* end loop age iage */
1.265     brouard  4829:       
1.251     brouard  4830:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4831:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4832:        if(posproptt < 1.e-5){
1.265     brouard  4833:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4834:        }else{
1.265     brouard  4835:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4836:        }
1.226     brouard  4837:       }
1.251     brouard  4838:       fprintf(ficresphtm,"</tr>\n");
                   4839:       fprintf(ficresphtm,"</table>\n");
                   4840:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4841:       if(posproptt < 1.e-5){
1.251     brouard  4842:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4843:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4844:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4845:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4846:        invalidvarcomb[j1]=1;
1.226     brouard  4847:       }else{
1.251     brouard  4848:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4849:        invalidvarcomb[j1]=0;
1.226     brouard  4850:       }
1.251     brouard  4851:       fprintf(ficresphtmfr,"</table>\n");
                   4852:       fprintf(ficlog,"\n");
                   4853:       if(j!=0){
                   4854:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4855:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4856:          for(k=1; k <=(nlstate+ndeath); k++){
                   4857:            if (k != i) {
1.265     brouard  4858:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4859:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4860:                  if(j1==1){ /* All dummy covariates to zero */
                   4861:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4862:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4863:                    printf("%d%d ",i,k);
                   4864:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4865:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4866:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4867:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4868:                  }
1.253     brouard  4869:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4870:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4871:                    x[iage]= (double)iage;
                   4872:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4873:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4874:                  }
1.268     brouard  4875:                  /* Some are not finite, but linreg will ignore these ages */
                   4876:                  no=0;
1.253     brouard  4877:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4878:                  pstart[s1]=b;
                   4879:                  pstart[s1-1]=a;
1.252     brouard  4880:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4881:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4882:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4883:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4884:                  printf("%d%d ",i,k);
                   4885:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4886:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4887:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4888:                  ;
                   4889:                }
                   4890:                /* printf("%12.7f )", param[i][jj][k]); */
                   4891:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4892:                s1++; 
1.251     brouard  4893:              } /* end jj */
                   4894:            } /* end k!= i */
                   4895:          } /* end k */
1.265     brouard  4896:        } /* end i, s1 */
1.251     brouard  4897:       } /* end j !=0 */
                   4898:     } /* end selected combination of covariate j1 */
                   4899:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4900:       printf("#Freqsummary: Starting values for the constants:\n");
                   4901:       fprintf(ficlog,"\n");
1.265     brouard  4902:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4903:        for(k=1; k <=(nlstate+ndeath); k++){
                   4904:          if (k != i) {
                   4905:            printf("%d%d ",i,k);
                   4906:            fprintf(ficlog,"%d%d ",i,k);
                   4907:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4908:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4909:              if(jj==1){ /* Age has to be done */
1.265     brouard  4910:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4911:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4912:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4913:              }
                   4914:              /* printf("%12.7f )", param[i][jj][k]); */
                   4915:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4916:              s1++; 
1.250     brouard  4917:            }
1.251     brouard  4918:            printf("\n");
                   4919:            fprintf(ficlog,"\n");
1.250     brouard  4920:          }
                   4921:        }
1.284     brouard  4922:       } /* end of state i */
1.251     brouard  4923:       printf("#Freqsummary\n");
                   4924:       fprintf(ficlog,"\n");
1.265     brouard  4925:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4926:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4927:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4928:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4929:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4930:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4931:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4932:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4933:          /* } */
                   4934:        }
1.265     brouard  4935:       } /* end loop s1 */
1.251     brouard  4936:       
                   4937:       printf("\n");
                   4938:       fprintf(ficlog,"\n");
                   4939:     } /* end j=0 */
1.249     brouard  4940:   } /* end j */
1.252     brouard  4941: 
1.253     brouard  4942:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4943:     for(i=1, jk=1; i <=nlstate; i++){
                   4944:       for(j=1; j <=nlstate+ndeath; j++){
                   4945:        if(j!=i){
                   4946:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4947:          printf("%1d%1d",i,j);
                   4948:          fprintf(ficparo,"%1d%1d",i,j);
                   4949:          for(k=1; k<=ncovmodel;k++){
                   4950:            /*    printf(" %lf",param[i][j][k]); */
                   4951:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4952:            p[jk]=pstart[jk];
                   4953:            printf(" %f ",pstart[jk]);
                   4954:            fprintf(ficparo," %f ",pstart[jk]);
                   4955:            jk++;
                   4956:          }
                   4957:          printf("\n");
                   4958:          fprintf(ficparo,"\n");
                   4959:        }
                   4960:       }
                   4961:     }
                   4962:   } /* end mle=-2 */
1.226     brouard  4963:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4964:   
1.226     brouard  4965:   fclose(ficresp);
                   4966:   fclose(ficresphtm);
                   4967:   fclose(ficresphtmfr);
1.283     brouard  4968:   free_vector(idq,1,nqfveff);
1.226     brouard  4969:   free_vector(meanq,1,nqfveff);
1.284     brouard  4970:   free_vector(stdq,1,nqfveff);
1.226     brouard  4971:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4972:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4973:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4974:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4975:   free_vector(pospropt,1,nlstate);
                   4976:   free_vector(posprop,1,nlstate);
1.251     brouard  4977:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4978:   free_vector(pp,1,nlstate);
                   4979:   /* End of freqsummary */
                   4980: }
1.126     brouard  4981: 
1.268     brouard  4982: /* Simple linear regression */
                   4983: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4984: 
                   4985:   /* y=a+bx regression */
                   4986:   double   sumx = 0.0;                        /* sum of x                      */
                   4987:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4988:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4989:   double   sumy = 0.0;                        /* sum of y                      */
                   4990:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4991:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4992:   double yhat;
                   4993:   
                   4994:   double denom=0;
                   4995:   int i;
                   4996:   int ne=*no;
                   4997:   
                   4998:   for ( i=ifi, ne=0;i<=ila;i++) {
                   4999:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5000:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5001:       continue;
                   5002:     }
                   5003:     ne=ne+1;
                   5004:     sumx  += x[i];       
                   5005:     sumx2 += x[i]*x[i];  
                   5006:     sumxy += x[i] * y[i];
                   5007:     sumy  += y[i];      
                   5008:     sumy2 += y[i]*y[i]; 
                   5009:     denom = (ne * sumx2 - sumx*sumx);
                   5010:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5011:   } 
                   5012:   
                   5013:   denom = (ne * sumx2 - sumx*sumx);
                   5014:   if (denom == 0) {
                   5015:     // vertical, slope m is infinity
                   5016:     *b = INFINITY;
                   5017:     *a = 0;
                   5018:     if (r) *r = 0;
                   5019:     return 1;
                   5020:   }
                   5021:   
                   5022:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5023:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5024:   if (r!=NULL) {
                   5025:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5026:       sqrt((sumx2 - sumx*sumx/ne) *
                   5027:           (sumy2 - sumy*sumy/ne));
                   5028:   }
                   5029:   *no=ne;
                   5030:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5031:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5032:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5033:       continue;
                   5034:     }
                   5035:     ne=ne+1;
                   5036:     yhat = y[i] - *a -*b* x[i];
                   5037:     sume2  += yhat * yhat ;       
                   5038:     
                   5039:     denom = (ne * sumx2 - sumx*sumx);
                   5040:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5041:   } 
                   5042:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5043:   *sa= *sb * sqrt(sumx2/ne);
                   5044:   
                   5045:   return 0; 
                   5046: }
                   5047: 
1.126     brouard  5048: /************ Prevalence ********************/
1.227     brouard  5049: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5050: {  
                   5051:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5052:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5053:      We still use firstpass and lastpass as another selection.
                   5054:   */
1.126     brouard  5055:  
1.227     brouard  5056:   int i, m, jk, j1, bool, z1,j, iv;
                   5057:   int mi; /* Effective wave */
                   5058:   int iage;
                   5059:   double agebegin, ageend;
                   5060: 
                   5061:   double **prop;
                   5062:   double posprop; 
                   5063:   double  y2; /* in fractional years */
                   5064:   int iagemin, iagemax;
                   5065:   int first; /** to stop verbosity which is redirected to log file */
                   5066: 
                   5067:   iagemin= (int) agemin;
                   5068:   iagemax= (int) agemax;
                   5069:   /*pp=vector(1,nlstate);*/
1.251     brouard  5070:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5071:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5072:   j1=0;
1.222     brouard  5073:   
1.227     brouard  5074:   /*j=cptcoveff;*/
                   5075:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5076:   
1.288     brouard  5077:   first=0;
1.227     brouard  5078:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5079:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5080:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5081:        prop[i][iage]=0.0;
                   5082:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5083:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5084:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5085:     
                   5086:     for (i=1; i<=imx; i++) { /* Each individual */
                   5087:       bool=1;
                   5088:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5089:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5090:        m=mw[mi][i];
                   5091:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5092:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5093:        for (z1=1; z1<=cptcoveff; z1++){
                   5094:          if( Fixed[Tmodelind[z1]]==1){
                   5095:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5096:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5097:              bool=0;
                   5098:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5099:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5100:              bool=0;
                   5101:            }
                   5102:        }
                   5103:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5104:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5105:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5106:          if(m >=firstpass && m <=lastpass){
                   5107:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5108:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5109:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5110:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5111:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5112:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5113:                exit(1);
                   5114:              }
                   5115:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5116:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5117:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5118:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5119:              } /* end valid statuses */ 
                   5120:            } /* end selection of dates */
                   5121:          } /* end selection of waves */
                   5122:        } /* end bool */
                   5123:       } /* end wave */
                   5124:     } /* end individual */
                   5125:     for(i=iagemin; i <= iagemax+3; i++){  
                   5126:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5127:        posprop += prop[jk][i]; 
                   5128:       } 
                   5129:       
                   5130:       for(jk=1; jk <=nlstate ; jk++){      
                   5131:        if( i <=  iagemax){ 
                   5132:          if(posprop>=1.e-5){ 
                   5133:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5134:          } else{
1.288     brouard  5135:            if(!first){
                   5136:              first=1;
1.266     brouard  5137:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5138:            }else{
1.288     brouard  5139:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5140:            }
                   5141:          }
                   5142:        } 
                   5143:       }/* end jk */ 
                   5144:     }/* end i */ 
1.222     brouard  5145:      /*} *//* end i1 */
1.227     brouard  5146:   } /* end j1 */
1.222     brouard  5147:   
1.227     brouard  5148:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5149:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5150:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5151: }  /* End of prevalence */
1.126     brouard  5152: 
                   5153: /************* Waves Concatenation ***************/
                   5154: 
                   5155: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5156: {
                   5157:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5158:      Death is a valid wave (if date is known).
                   5159:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5160:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5161:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5162:   */
1.126     brouard  5163: 
1.224     brouard  5164:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5165:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5166:      double sum=0., jmean=0.;*/
1.224     brouard  5167:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5168:   int j, k=0,jk, ju, jl;
                   5169:   double sum=0.;
                   5170:   first=0;
1.214     brouard  5171:   firstwo=0;
1.217     brouard  5172:   firsthree=0;
1.218     brouard  5173:   firstfour=0;
1.164     brouard  5174:   jmin=100000;
1.126     brouard  5175:   jmax=-1;
                   5176:   jmean=0.;
1.224     brouard  5177: 
                   5178: /* Treating live states */
1.214     brouard  5179:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5180:     mi=0;  /* First valid wave */
1.227     brouard  5181:     mli=0; /* Last valid wave */
1.126     brouard  5182:     m=firstpass;
1.214     brouard  5183:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5184:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5185:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5186:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5187:        mw[++mi][i]=m;
                   5188:        mli=m;
1.224     brouard  5189:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5190:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5191:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5192:       }
1.227     brouard  5193:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5194: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5195:        break;
1.224     brouard  5196: #else
1.227     brouard  5197:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5198:          if(firsthree == 0){
1.262     brouard  5199:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5200:            firsthree=1;
                   5201:          }
1.262     brouard  5202:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5203:          mw[++mi][i]=m;
                   5204:          mli=m;
                   5205:        }
                   5206:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5207:          nbwarn++;
                   5208:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5209:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5210:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5211:          }
                   5212:          break;
                   5213:        }
                   5214:        break;
1.224     brouard  5215: #endif
1.227     brouard  5216:       }/* End m >= lastpass */
1.126     brouard  5217:     }/* end while */
1.224     brouard  5218: 
1.227     brouard  5219:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5220:     /* After last pass */
1.224     brouard  5221: /* Treating death states */
1.214     brouard  5222:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5223:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5224:       /* } */
1.126     brouard  5225:       mi++;    /* Death is another wave */
                   5226:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5227:       /* Only death is a correct wave */
1.126     brouard  5228:       mw[mi][i]=m;
1.257     brouard  5229:     } /* else not in a death state */
1.224     brouard  5230: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5231:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5232:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5233:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5234:          nbwarn++;
                   5235:          if(firstfiv==0){
                   5236:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5237:            firstfiv=1;
                   5238:          }else{
                   5239:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5240:          }
                   5241:        }else{ /* Death occured afer last wave potential bias */
                   5242:          nberr++;
                   5243:          if(firstwo==0){
1.257     brouard  5244:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5245:            firstwo=1;
                   5246:          }
1.257     brouard  5247:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5248:        }
1.257     brouard  5249:       }else{ /* if date of interview is unknown */
1.227     brouard  5250:        /* death is known but not confirmed by death status at any wave */
                   5251:        if(firstfour==0){
                   5252:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5253:          firstfour=1;
                   5254:        }
                   5255:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5256:       }
1.224     brouard  5257:     } /* end if date of death is known */
                   5258: #endif
                   5259:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5260:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5261:     if(mi==0){
                   5262:       nbwarn++;
                   5263:       if(first==0){
1.227     brouard  5264:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5265:        first=1;
1.126     brouard  5266:       }
                   5267:       if(first==1){
1.227     brouard  5268:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5269:       }
                   5270:     } /* end mi==0 */
                   5271:   } /* End individuals */
1.214     brouard  5272:   /* wav and mw are no more changed */
1.223     brouard  5273:        
1.214     brouard  5274:   
1.126     brouard  5275:   for(i=1; i<=imx; i++){
                   5276:     for(mi=1; mi<wav[i];mi++){
                   5277:       if (stepm <=0)
1.227     brouard  5278:        dh[mi][i]=1;
1.126     brouard  5279:       else{
1.260     brouard  5280:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5281:          if (agedc[i] < 2*AGESUP) {
                   5282:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5283:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5284:            else if(j<0){
                   5285:              nberr++;
                   5286:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5287:              j=1; /* Temporary Dangerous patch */
                   5288:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5289:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5290:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5291:            }
                   5292:            k=k+1;
                   5293:            if (j >= jmax){
                   5294:              jmax=j;
                   5295:              ijmax=i;
                   5296:            }
                   5297:            if (j <= jmin){
                   5298:              jmin=j;
                   5299:              ijmin=i;
                   5300:            }
                   5301:            sum=sum+j;
                   5302:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5303:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5304:          }
                   5305:        }
                   5306:        else{
                   5307:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5308: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5309:                                        
1.227     brouard  5310:          k=k+1;
                   5311:          if (j >= jmax) {
                   5312:            jmax=j;
                   5313:            ijmax=i;
                   5314:          }
                   5315:          else if (j <= jmin){
                   5316:            jmin=j;
                   5317:            ijmin=i;
                   5318:          }
                   5319:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5320:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5321:          if(j<0){
                   5322:            nberr++;
                   5323:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5324:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5325:          }
                   5326:          sum=sum+j;
                   5327:        }
                   5328:        jk= j/stepm;
                   5329:        jl= j -jk*stepm;
                   5330:        ju= j -(jk+1)*stepm;
                   5331:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5332:          if(jl==0){
                   5333:            dh[mi][i]=jk;
                   5334:            bh[mi][i]=0;
                   5335:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5336:                  * to avoid the price of an extra matrix product in likelihood */
                   5337:            dh[mi][i]=jk+1;
                   5338:            bh[mi][i]=ju;
                   5339:          }
                   5340:        }else{
                   5341:          if(jl <= -ju){
                   5342:            dh[mi][i]=jk;
                   5343:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5344:                                 * is higher than the multiple of stepm and negative otherwise.
                   5345:                                 */
                   5346:          }
                   5347:          else{
                   5348:            dh[mi][i]=jk+1;
                   5349:            bh[mi][i]=ju;
                   5350:          }
                   5351:          if(dh[mi][i]==0){
                   5352:            dh[mi][i]=1; /* At least one step */
                   5353:            bh[mi][i]=ju; /* At least one step */
                   5354:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5355:          }
                   5356:        } /* end if mle */
1.126     brouard  5357:       }
                   5358:     } /* end wave */
                   5359:   }
                   5360:   jmean=sum/k;
                   5361:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5362:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5363: }
1.126     brouard  5364: 
                   5365: /*********** Tricode ****************************/
1.220     brouard  5366:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5367:  {
                   5368:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5369:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5370:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5371:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5372:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5373:     */
1.130     brouard  5374: 
1.242     brouard  5375:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5376:    int modmaxcovj=0; /* Modality max of covariates j */
                   5377:    int cptcode=0; /* Modality max of covariates j */
                   5378:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5379: 
                   5380: 
1.242     brouard  5381:    /* cptcoveff=0;  */
                   5382:    /* *cptcov=0; */
1.126     brouard  5383:  
1.242     brouard  5384:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5385:    for (k=1; k <= maxncov; k++)
                   5386:      for(j=1; j<=2; j++)
                   5387:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5388: 
1.242     brouard  5389:    /* Loop on covariates without age and products and no quantitative variable */
                   5390:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5391:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5392:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5393:        switch(Fixed[k]) {
                   5394:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5395:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5396:           ij=(int)(covar[Tvar[k]][i]);
                   5397:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5398:            * If product of Vn*Vm, still boolean *:
                   5399:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5400:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5401:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5402:              modality of the nth covariate of individual i. */
                   5403:           if (ij > modmaxcovj)
                   5404:             modmaxcovj=ij; 
                   5405:           else if (ij < modmincovj) 
                   5406:             modmincovj=ij; 
1.287     brouard  5407:           if (ij <0 || ij >1 ){
                   5408:             printf("Information, IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5409:             fprintf(ficlog,"Information, currently IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5410:           }
                   5411:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5412:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5413:             exit(1);
                   5414:           }else
                   5415:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5416:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5417:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5418:           /* getting the maximum value of the modality of the covariate
                   5419:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5420:              female ies 1, then modmaxcovj=1.
                   5421:           */
                   5422:         } /* end for loop on individuals i */
                   5423:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5424:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5425:         cptcode=modmaxcovj;
                   5426:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5427:         /*for (i=0; i<=cptcode; i++) {*/
                   5428:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5429:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5430:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5431:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5432:             if( j != -1){
                   5433:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5434:                                  covariate for which somebody answered excluding 
                   5435:                                  undefined. Usually 2: 0 and 1. */
                   5436:             }
                   5437:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5438:                                     covariate for which somebody answered including 
                   5439:                                     undefined. Usually 3: -1, 0 and 1. */
                   5440:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5441:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5442:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5443:                        
1.242     brouard  5444:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5445:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5446:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5447:         /* modmincovj=3; modmaxcovj = 7; */
                   5448:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5449:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5450:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5451:         /* nbcode[Tvar[j]][ij]=k; */
                   5452:         /* nbcode[Tvar[j]][1]=0; */
                   5453:         /* nbcode[Tvar[j]][2]=1; */
                   5454:         /* nbcode[Tvar[j]][3]=2; */
                   5455:         /* To be continued (not working yet). */
                   5456:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5457: 
                   5458:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5459:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5460:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5461:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5462:         /*, could be restored in the future */
                   5463:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5464:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5465:             break;
                   5466:           }
                   5467:           ij++;
1.287     brouard  5468:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5469:           cptcode = ij; /* New max modality for covar j */
                   5470:         } /* end of loop on modality i=-1 to 1 or more */
                   5471:         break;
                   5472:        case 1: /* Testing on varying covariate, could be simple and
                   5473:                * should look at waves or product of fixed *
                   5474:                * varying. No time to test -1, assuming 0 and 1 only */
                   5475:         ij=0;
                   5476:         for(i=0; i<=1;i++){
                   5477:           nbcode[Tvar[k]][++ij]=i;
                   5478:         }
                   5479:         break;
                   5480:        default:
                   5481:         break;
                   5482:        } /* end switch */
                   5483:      } /* end dummy test */
1.287     brouard  5484:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5485:   
                   5486:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5487:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5488:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5489:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5490:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5491:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5492:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5493:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5494:   
                   5495:    ij=0;
                   5496:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5497:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5498:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5499:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5500:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5501:        /* If product not in single variable we don't print results */
                   5502:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5503:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5504:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5505:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5506:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5507:        if(Fixed[k]!=0)
                   5508:         anyvaryingduminmodel=1;
                   5509:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5510:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5511:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5512:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5513:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5514:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5515:      } 
                   5516:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5517:    /* ij--; */
                   5518:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5519:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5520:                * because they can be excluded from the model and real
                   5521:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5522:    for(j=ij+1; j<= cptcovt; j++){
                   5523:      Tvaraff[j]=0;
                   5524:      Tmodelind[j]=0;
                   5525:    }
                   5526:    for(j=ntveff+1; j<= cptcovt; j++){
                   5527:      TmodelInvind[j]=0;
                   5528:    }
                   5529:    /* To be sorted */
                   5530:    ;
                   5531:  }
1.126     brouard  5532: 
1.145     brouard  5533: 
1.126     brouard  5534: /*********** Health Expectancies ****************/
                   5535: 
1.235     brouard  5536:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5537: 
                   5538: {
                   5539:   /* Health expectancies, no variances */
1.164     brouard  5540:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5541:   int nhstepma, nstepma; /* Decreasing with age */
                   5542:   double age, agelim, hf;
                   5543:   double ***p3mat;
                   5544:   double eip;
                   5545: 
1.238     brouard  5546:   /* pstamp(ficreseij); */
1.126     brouard  5547:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5548:   fprintf(ficreseij,"# Age");
                   5549:   for(i=1; i<=nlstate;i++){
                   5550:     for(j=1; j<=nlstate;j++){
                   5551:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5552:     }
                   5553:     fprintf(ficreseij," e%1d. ",i);
                   5554:   }
                   5555:   fprintf(ficreseij,"\n");
                   5556: 
                   5557:   
                   5558:   if(estepm < stepm){
                   5559:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5560:   }
                   5561:   else  hstepm=estepm;   
                   5562:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5563:    * This is mainly to measure the difference between two models: for example
                   5564:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5565:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5566:    * progression in between and thus overestimating or underestimating according
                   5567:    * to the curvature of the survival function. If, for the same date, we 
                   5568:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5569:    * to compare the new estimate of Life expectancy with the same linear 
                   5570:    * hypothesis. A more precise result, taking into account a more precise
                   5571:    * curvature will be obtained if estepm is as small as stepm. */
                   5572: 
                   5573:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5574:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5575:      nhstepm is the number of hstepm from age to agelim 
                   5576:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5577:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5578:      and note for a fixed period like estepm months */
                   5579:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5580:      survival function given by stepm (the optimization length). Unfortunately it
                   5581:      means that if the survival funtion is printed only each two years of age and if
                   5582:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5583:      results. So we changed our mind and took the option of the best precision.
                   5584:   */
                   5585:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5586: 
                   5587:   agelim=AGESUP;
                   5588:   /* If stepm=6 months */
                   5589:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5590:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5591:     
                   5592: /* nhstepm age range expressed in number of stepm */
                   5593:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5594:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5595:   /* if (stepm >= YEARM) hstepm=1;*/
                   5596:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5597:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5598: 
                   5599:   for (age=bage; age<=fage; age ++){ 
                   5600:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5601:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5602:     /* if (stepm >= YEARM) hstepm=1;*/
                   5603:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5604: 
                   5605:     /* If stepm=6 months */
                   5606:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5607:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5608:     
1.235     brouard  5609:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5610:     
                   5611:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5612:     
                   5613:     printf("%d|",(int)age);fflush(stdout);
                   5614:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5615:     
                   5616:     /* Computing expectancies */
                   5617:     for(i=1; i<=nlstate;i++)
                   5618:       for(j=1; j<=nlstate;j++)
                   5619:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5620:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5621:          
                   5622:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5623: 
                   5624:        }
                   5625: 
                   5626:     fprintf(ficreseij,"%3.0f",age );
                   5627:     for(i=1; i<=nlstate;i++){
                   5628:       eip=0;
                   5629:       for(j=1; j<=nlstate;j++){
                   5630:        eip +=eij[i][j][(int)age];
                   5631:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5632:       }
                   5633:       fprintf(ficreseij,"%9.4f", eip );
                   5634:     }
                   5635:     fprintf(ficreseij,"\n");
                   5636:     
                   5637:   }
                   5638:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5639:   printf("\n");
                   5640:   fprintf(ficlog,"\n");
                   5641:   
                   5642: }
                   5643: 
1.235     brouard  5644:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5645: 
                   5646: {
                   5647:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5648:      to initial status i, ei. .
1.126     brouard  5649:   */
                   5650:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5651:   int nhstepma, nstepma; /* Decreasing with age */
                   5652:   double age, agelim, hf;
                   5653:   double ***p3matp, ***p3matm, ***varhe;
                   5654:   double **dnewm,**doldm;
                   5655:   double *xp, *xm;
                   5656:   double **gp, **gm;
                   5657:   double ***gradg, ***trgradg;
                   5658:   int theta;
                   5659: 
                   5660:   double eip, vip;
                   5661: 
                   5662:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5663:   xp=vector(1,npar);
                   5664:   xm=vector(1,npar);
                   5665:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5666:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5667:   
                   5668:   pstamp(ficresstdeij);
                   5669:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5670:   fprintf(ficresstdeij,"# Age");
                   5671:   for(i=1; i<=nlstate;i++){
                   5672:     for(j=1; j<=nlstate;j++)
                   5673:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5674:     fprintf(ficresstdeij," e%1d. ",i);
                   5675:   }
                   5676:   fprintf(ficresstdeij,"\n");
                   5677: 
                   5678:   pstamp(ficrescveij);
                   5679:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5680:   fprintf(ficrescveij,"# Age");
                   5681:   for(i=1; i<=nlstate;i++)
                   5682:     for(j=1; j<=nlstate;j++){
                   5683:       cptj= (j-1)*nlstate+i;
                   5684:       for(i2=1; i2<=nlstate;i2++)
                   5685:        for(j2=1; j2<=nlstate;j2++){
                   5686:          cptj2= (j2-1)*nlstate+i2;
                   5687:          if(cptj2 <= cptj)
                   5688:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5689:        }
                   5690:     }
                   5691:   fprintf(ficrescveij,"\n");
                   5692:   
                   5693:   if(estepm < stepm){
                   5694:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5695:   }
                   5696:   else  hstepm=estepm;   
                   5697:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5698:    * This is mainly to measure the difference between two models: for example
                   5699:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5700:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5701:    * progression in between and thus overestimating or underestimating according
                   5702:    * to the curvature of the survival function. If, for the same date, we 
                   5703:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5704:    * to compare the new estimate of Life expectancy with the same linear 
                   5705:    * hypothesis. A more precise result, taking into account a more precise
                   5706:    * curvature will be obtained if estepm is as small as stepm. */
                   5707: 
                   5708:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5709:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5710:      nhstepm is the number of hstepm from age to agelim 
                   5711:      nstepm is the number of stepm from age to agelin. 
                   5712:      Look at hpijx to understand the reason of that which relies in memory size
                   5713:      and note for a fixed period like estepm months */
                   5714:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5715:      survival function given by stepm (the optimization length). Unfortunately it
                   5716:      means that if the survival funtion is printed only each two years of age and if
                   5717:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5718:      results. So we changed our mind and took the option of the best precision.
                   5719:   */
                   5720:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5721: 
                   5722:   /* If stepm=6 months */
                   5723:   /* nhstepm age range expressed in number of stepm */
                   5724:   agelim=AGESUP;
                   5725:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5726:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5727:   /* if (stepm >= YEARM) hstepm=1;*/
                   5728:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5729:   
                   5730:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5731:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5732:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5733:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5734:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5735:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5736: 
                   5737:   for (age=bage; age<=fage; age ++){ 
                   5738:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5739:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5740:     /* if (stepm >= YEARM) hstepm=1;*/
                   5741:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5742:                
1.126     brouard  5743:     /* If stepm=6 months */
                   5744:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5745:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5746:     
                   5747:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5748:                
1.126     brouard  5749:     /* Computing  Variances of health expectancies */
                   5750:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5751:        decrease memory allocation */
                   5752:     for(theta=1; theta <=npar; theta++){
                   5753:       for(i=1; i<=npar; i++){ 
1.222     brouard  5754:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5755:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5756:       }
1.235     brouard  5757:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5758:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5759:                        
1.126     brouard  5760:       for(j=1; j<= nlstate; j++){
1.222     brouard  5761:        for(i=1; i<=nlstate; i++){
                   5762:          for(h=0; h<=nhstepm-1; h++){
                   5763:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5764:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5765:          }
                   5766:        }
1.126     brouard  5767:       }
1.218     brouard  5768:                        
1.126     brouard  5769:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5770:        for(h=0; h<=nhstepm-1; h++){
                   5771:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5772:        }
1.126     brouard  5773:     }/* End theta */
                   5774:     
                   5775:     
                   5776:     for(h=0; h<=nhstepm-1; h++)
                   5777:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5778:        for(theta=1; theta <=npar; theta++)
                   5779:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5780:     
1.218     brouard  5781:                
1.222     brouard  5782:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5783:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5784:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5785:                
1.222     brouard  5786:     printf("%d|",(int)age);fflush(stdout);
                   5787:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5788:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5789:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5790:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5791:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5792:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5793:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5794:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5795:       }
                   5796:     }
1.218     brouard  5797:                
1.126     brouard  5798:     /* Computing expectancies */
1.235     brouard  5799:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5800:     for(i=1; i<=nlstate;i++)
                   5801:       for(j=1; j<=nlstate;j++)
1.222     brouard  5802:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5803:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5804:                                        
1.222     brouard  5805:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5806:                                        
1.222     brouard  5807:        }
1.269     brouard  5808: 
                   5809:     /* Standard deviation of expectancies ij */                
1.126     brouard  5810:     fprintf(ficresstdeij,"%3.0f",age );
                   5811:     for(i=1; i<=nlstate;i++){
                   5812:       eip=0.;
                   5813:       vip=0.;
                   5814:       for(j=1; j<=nlstate;j++){
1.222     brouard  5815:        eip += eij[i][j][(int)age];
                   5816:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5817:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5818:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5819:       }
                   5820:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5821:     }
                   5822:     fprintf(ficresstdeij,"\n");
1.218     brouard  5823:                
1.269     brouard  5824:     /* Variance of expectancies ij */          
1.126     brouard  5825:     fprintf(ficrescveij,"%3.0f",age );
                   5826:     for(i=1; i<=nlstate;i++)
                   5827:       for(j=1; j<=nlstate;j++){
1.222     brouard  5828:        cptj= (j-1)*nlstate+i;
                   5829:        for(i2=1; i2<=nlstate;i2++)
                   5830:          for(j2=1; j2<=nlstate;j2++){
                   5831:            cptj2= (j2-1)*nlstate+i2;
                   5832:            if(cptj2 <= cptj)
                   5833:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5834:          }
1.126     brouard  5835:       }
                   5836:     fprintf(ficrescveij,"\n");
1.218     brouard  5837:                
1.126     brouard  5838:   }
                   5839:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5840:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5841:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5842:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5843:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5844:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5845:   printf("\n");
                   5846:   fprintf(ficlog,"\n");
1.218     brouard  5847:        
1.126     brouard  5848:   free_vector(xm,1,npar);
                   5849:   free_vector(xp,1,npar);
                   5850:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5851:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5852:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5853: }
1.218     brouard  5854:  
1.126     brouard  5855: /************ Variance ******************/
1.235     brouard  5856:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5857:  {
1.279     brouard  5858:    /** Variance of health expectancies 
                   5859:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5860:     * double **newm;
                   5861:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5862:     */
1.218     brouard  5863:   
                   5864:    /* int movingaverage(); */
                   5865:    double **dnewm,**doldm;
                   5866:    double **dnewmp,**doldmp;
                   5867:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  5868:    int first=0;
1.218     brouard  5869:    int k;
                   5870:    double *xp;
1.279     brouard  5871:    double **gp, **gm;  /**< for var eij */
                   5872:    double ***gradg, ***trgradg; /**< for var eij */
                   5873:    double **gradgp, **trgradgp; /**< for var p point j */
                   5874:    double *gpp, *gmp; /**< for var p point j */
                   5875:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5876:    double ***p3mat;
                   5877:    double age,agelim, hf;
                   5878:    /* double ***mobaverage; */
                   5879:    int theta;
                   5880:    char digit[4];
                   5881:    char digitp[25];
                   5882: 
                   5883:    char fileresprobmorprev[FILENAMELENGTH];
                   5884: 
                   5885:    if(popbased==1){
                   5886:      if(mobilav!=0)
                   5887:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5888:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5889:    }
                   5890:    else 
                   5891:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5892: 
1.218     brouard  5893:    /* if (mobilav!=0) { */
                   5894:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5895:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5896:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5897:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5898:    /*   } */
                   5899:    /* } */
                   5900: 
                   5901:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5902:    sprintf(digit,"%-d",ij);
                   5903:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5904:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5905:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5906:    strcat(fileresprobmorprev,fileresu);
                   5907:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5908:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5909:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5910:    }
                   5911:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5912:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5913:    pstamp(ficresprobmorprev);
                   5914:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5915:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5916:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5917:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5918:    }
                   5919:    for(j=1;j<=cptcoveff;j++) 
                   5920:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5921:    fprintf(ficresprobmorprev,"\n");
                   5922: 
1.218     brouard  5923:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5924:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5925:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5926:      for(i=1; i<=nlstate;i++)
                   5927:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5928:    }  
                   5929:    fprintf(ficresprobmorprev,"\n");
                   5930:   
                   5931:    fprintf(ficgp,"\n# Routine varevsij");
                   5932:    fprintf(ficgp,"\nunset title \n");
                   5933:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5934:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5935:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  5936: 
1.218     brouard  5937:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5938:    pstamp(ficresvij);
                   5939:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5940:    if(popbased==1)
                   5941:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5942:    else
                   5943:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5944:    fprintf(ficresvij,"# Age");
                   5945:    for(i=1; i<=nlstate;i++)
                   5946:      for(j=1; j<=nlstate;j++)
                   5947:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5948:    fprintf(ficresvij,"\n");
                   5949: 
                   5950:    xp=vector(1,npar);
                   5951:    dnewm=matrix(1,nlstate,1,npar);
                   5952:    doldm=matrix(1,nlstate,1,nlstate);
                   5953:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5954:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5955: 
                   5956:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5957:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5958:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5959:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5960:   
1.218     brouard  5961:    if(estepm < stepm){
                   5962:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5963:    }
                   5964:    else  hstepm=estepm;   
                   5965:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5966:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5967:       nhstepm is the number of hstepm from age to agelim 
                   5968:       nstepm is the number of stepm from age to agelim. 
                   5969:       Look at function hpijx to understand why because of memory size limitations, 
                   5970:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5971:       survival function given by stepm (the optimization length). Unfortunately it
                   5972:       means that if the survival funtion is printed every two years of age and if
                   5973:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5974:       results. So we changed our mind and took the option of the best precision.
                   5975:    */
                   5976:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5977:    agelim = AGESUP;
                   5978:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5979:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5980:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5981:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5982:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5983:      gp=matrix(0,nhstepm,1,nlstate);
                   5984:      gm=matrix(0,nhstepm,1,nlstate);
                   5985:                
                   5986:                
                   5987:      for(theta=1; theta <=npar; theta++){
                   5988:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5989:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5990:        }
1.279     brouard  5991:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   5992:        * returns into prlim .
1.288     brouard  5993:        */
1.242     brouard  5994:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  5995: 
                   5996:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  5997:        if (popbased==1) {
                   5998:         if(mobilav ==0){
                   5999:           for(i=1; i<=nlstate;i++)
                   6000:             prlim[i][i]=probs[(int)age][i][ij];
                   6001:         }else{ /* mobilav */ 
                   6002:           for(i=1; i<=nlstate;i++)
                   6003:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6004:         }
                   6005:        }
1.279     brouard  6006:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}_x\f$ at horizon h.
                   6007:        */                      
                   6008:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
                   6009:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}_x\f$, which are the probability
                   6010:        * at horizon h in state j including mortality.
                   6011:        */
1.218     brouard  6012:        for(j=1; j<= nlstate; j++){
                   6013:         for(h=0; h<=nhstepm; h++){
                   6014:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6015:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6016:         }
                   6017:        }
1.279     brouard  6018:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6019:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6020:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6021:        */
                   6022:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6023:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6024:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6025:        }
                   6026:        
                   6027:        /* Again with minus shift */
1.218     brouard  6028:                        
                   6029:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6030:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6031: 
1.242     brouard  6032:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6033:                        
                   6034:        if (popbased==1) {
                   6035:         if(mobilav ==0){
                   6036:           for(i=1; i<=nlstate;i++)
                   6037:             prlim[i][i]=probs[(int)age][i][ij];
                   6038:         }else{ /* mobilav */ 
                   6039:           for(i=1; i<=nlstate;i++)
                   6040:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6041:         }
                   6042:        }
                   6043:                        
1.235     brouard  6044:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6045:                        
                   6046:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6047:         for(h=0; h<=nhstepm; h++){
                   6048:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6049:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6050:         }
                   6051:        }
                   6052:        /* This for computing probability of death (h=1 means
                   6053:          computed over hstepm matrices product = hstepm*stepm months) 
                   6054:          as a weighted average of prlim.
                   6055:        */
                   6056:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6057:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6058:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6059:        }    
1.279     brouard  6060:        /* end shifting computations */
                   6061: 
                   6062:        /**< Computing gradient matrix at horizon h 
                   6063:        */
1.218     brouard  6064:        for(j=1; j<= nlstate; j++) /* vareij */
                   6065:         for(h=0; h<=nhstepm; h++){
                   6066:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6067:         }
1.279     brouard  6068:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6069:        */
                   6070:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6071:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6072:        }
                   6073:                        
                   6074:      } /* End theta */
1.279     brouard  6075:      
                   6076:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6077:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6078:                
                   6079:      for(h=0; h<=nhstepm; h++) /* veij */
                   6080:        for(j=1; j<=nlstate;j++)
                   6081:         for(theta=1; theta <=npar; theta++)
                   6082:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6083:                
                   6084:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6085:        for(theta=1; theta <=npar; theta++)
                   6086:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6087:      /**< as well as its transposed matrix 
                   6088:       */               
1.218     brouard  6089:                
                   6090:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6091:      for(i=1;i<=nlstate;i++)
                   6092:        for(j=1;j<=nlstate;j++)
                   6093:         vareij[i][j][(int)age] =0.;
1.279     brouard  6094: 
                   6095:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6096:       * and k (nhstepm) formula 15 of article
                   6097:       * Lievre-Brouard-Heathcote
                   6098:       */
                   6099:      
1.218     brouard  6100:      for(h=0;h<=nhstepm;h++){
                   6101:        for(k=0;k<=nhstepm;k++){
                   6102:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6103:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6104:         for(i=1;i<=nlstate;i++)
                   6105:           for(j=1;j<=nlstate;j++)
                   6106:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6107:        }
                   6108:      }
                   6109:                
1.279     brouard  6110:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6111:       * p.j overall mortality formula 49 but computed directly because
                   6112:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6113:       * wix is independent of theta.
                   6114:       */
1.218     brouard  6115:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6116:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6117:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6118:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6119:         varppt[j][i]=doldmp[j][i];
                   6120:      /* end ppptj */
                   6121:      /*  x centered again */
                   6122:                
1.242     brouard  6123:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6124:                
                   6125:      if (popbased==1) {
                   6126:        if(mobilav ==0){
                   6127:         for(i=1; i<=nlstate;i++)
                   6128:           prlim[i][i]=probs[(int)age][i][ij];
                   6129:        }else{ /* mobilav */ 
                   6130:         for(i=1; i<=nlstate;i++)
                   6131:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6132:        }
                   6133:      }
                   6134:                
                   6135:      /* This for computing probability of death (h=1 means
                   6136:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6137:        as a weighted average of prlim.
                   6138:      */
1.235     brouard  6139:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6140:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6141:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6142:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6143:      }    
                   6144:      /* end probability of death */
                   6145:                
                   6146:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6147:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6148:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6149:        for(i=1; i<=nlstate;i++){
                   6150:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6151:        }
                   6152:      } 
                   6153:      fprintf(ficresprobmorprev,"\n");
                   6154:                
                   6155:      fprintf(ficresvij,"%.0f ",age );
                   6156:      for(i=1; i<=nlstate;i++)
                   6157:        for(j=1; j<=nlstate;j++){
                   6158:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6159:        }
                   6160:      fprintf(ficresvij,"\n");
                   6161:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6162:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6163:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6164:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6165:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6166:    } /* End age */
                   6167:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6168:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6169:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6170:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6171:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6172:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6173:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6174:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6175:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6176:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6177:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6178:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6179:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6180:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6181:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6182:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6183:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6184:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6185:     */
1.218     brouard  6186:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6187:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6188: 
1.218     brouard  6189:    free_vector(xp,1,npar);
                   6190:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6191:    free_matrix(dnewm,1,nlstate,1,npar);
                   6192:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6193:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6194:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6195:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6196:    fclose(ficresprobmorprev);
                   6197:    fflush(ficgp);
                   6198:    fflush(fichtm); 
                   6199:  }  /* end varevsij */
1.126     brouard  6200: 
                   6201: /************ Variance of prevlim ******************/
1.269     brouard  6202:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6203: {
1.205     brouard  6204:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6205:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6206: 
1.268     brouard  6207:   double **dnewmpar,**doldm;
1.126     brouard  6208:   int i, j, nhstepm, hstepm;
                   6209:   double *xp;
                   6210:   double *gp, *gm;
                   6211:   double **gradg, **trgradg;
1.208     brouard  6212:   double **mgm, **mgp;
1.126     brouard  6213:   double age,agelim;
                   6214:   int theta;
                   6215:   
                   6216:   pstamp(ficresvpl);
1.288     brouard  6217:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6218:   fprintf(ficresvpl,"# Age ");
                   6219:   if(nresult >=1)
                   6220:     fprintf(ficresvpl," Result# ");
1.126     brouard  6221:   for(i=1; i<=nlstate;i++)
                   6222:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6223:   fprintf(ficresvpl,"\n");
                   6224: 
                   6225:   xp=vector(1,npar);
1.268     brouard  6226:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6227:   doldm=matrix(1,nlstate,1,nlstate);
                   6228:   
                   6229:   hstepm=1*YEARM; /* Every year of age */
                   6230:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6231:   agelim = AGESUP;
                   6232:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6233:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6234:     if (stepm >= YEARM) hstepm=1;
                   6235:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6236:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6237:     mgp=matrix(1,npar,1,nlstate);
                   6238:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6239:     gp=vector(1,nlstate);
                   6240:     gm=vector(1,nlstate);
                   6241: 
                   6242:     for(theta=1; theta <=npar; theta++){
                   6243:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6244:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6245:       }
1.288     brouard  6246:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6247:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6248:       /* else */
                   6249:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6250:       for(i=1;i<=nlstate;i++){
1.126     brouard  6251:        gp[i] = prlim[i][i];
1.208     brouard  6252:        mgp[theta][i] = prlim[i][i];
                   6253:       }
1.126     brouard  6254:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6255:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6256:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6257:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6258:       /* else */
                   6259:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6260:       for(i=1;i<=nlstate;i++){
1.126     brouard  6261:        gm[i] = prlim[i][i];
1.208     brouard  6262:        mgm[theta][i] = prlim[i][i];
                   6263:       }
1.126     brouard  6264:       for(i=1;i<=nlstate;i++)
                   6265:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6266:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6267:     } /* End theta */
                   6268: 
                   6269:     trgradg =matrix(1,nlstate,1,npar);
                   6270: 
                   6271:     for(j=1; j<=nlstate;j++)
                   6272:       for(theta=1; theta <=npar; theta++)
                   6273:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6274:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6275:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6276:     /*   for(j=1; j<=nlstate;j++){ */
                   6277:     /*         printf(" %d ",j); */
                   6278:     /*         for(theta=1; theta <=npar; theta++) */
                   6279:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6280:     /*         printf("\n "); */
                   6281:     /*   } */
                   6282:     /* } */
                   6283:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6284:     /*   printf("\n gradg %d ",(int)age); */
                   6285:     /*   for(j=1; j<=nlstate;j++){ */
                   6286:     /*         printf("%d ",j); */
                   6287:     /*         for(theta=1; theta <=npar; theta++) */
                   6288:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6289:     /*         printf("\n "); */
                   6290:     /*   } */
                   6291:     /* } */
1.126     brouard  6292: 
                   6293:     for(i=1;i<=nlstate;i++)
                   6294:       varpl[i][(int)age] =0.;
1.209     brouard  6295:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6296:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6297:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6298:     }else{
1.268     brouard  6299:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6300:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6301:     }
1.126     brouard  6302:     for(i=1;i<=nlstate;i++)
                   6303:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6304: 
                   6305:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6306:     if(nresult >=1)
                   6307:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6308:     for(i=1; i<=nlstate;i++){
1.126     brouard  6309:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6310:       /* for(j=1;j<=nlstate;j++) */
                   6311:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6312:     }
1.126     brouard  6313:     fprintf(ficresvpl,"\n");
                   6314:     free_vector(gp,1,nlstate);
                   6315:     free_vector(gm,1,nlstate);
1.208     brouard  6316:     free_matrix(mgm,1,npar,1,nlstate);
                   6317:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6318:     free_matrix(gradg,1,npar,1,nlstate);
                   6319:     free_matrix(trgradg,1,nlstate,1,npar);
                   6320:   } /* End age */
                   6321: 
                   6322:   free_vector(xp,1,npar);
                   6323:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6324:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6325: 
                   6326: }
                   6327: 
                   6328: 
                   6329: /************ Variance of backprevalence limit ******************/
1.269     brouard  6330:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6331: {
                   6332:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6333:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6334: 
                   6335:   double **dnewmpar,**doldm;
                   6336:   int i, j, nhstepm, hstepm;
                   6337:   double *xp;
                   6338:   double *gp, *gm;
                   6339:   double **gradg, **trgradg;
                   6340:   double **mgm, **mgp;
                   6341:   double age,agelim;
                   6342:   int theta;
                   6343:   
                   6344:   pstamp(ficresvbl);
                   6345:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6346:   fprintf(ficresvbl,"# Age ");
                   6347:   if(nresult >=1)
                   6348:     fprintf(ficresvbl," Result# ");
                   6349:   for(i=1; i<=nlstate;i++)
                   6350:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6351:   fprintf(ficresvbl,"\n");
                   6352: 
                   6353:   xp=vector(1,npar);
                   6354:   dnewmpar=matrix(1,nlstate,1,npar);
                   6355:   doldm=matrix(1,nlstate,1,nlstate);
                   6356:   
                   6357:   hstepm=1*YEARM; /* Every year of age */
                   6358:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6359:   agelim = AGEINF;
                   6360:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6361:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6362:     if (stepm >= YEARM) hstepm=1;
                   6363:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6364:     gradg=matrix(1,npar,1,nlstate);
                   6365:     mgp=matrix(1,npar,1,nlstate);
                   6366:     mgm=matrix(1,npar,1,nlstate);
                   6367:     gp=vector(1,nlstate);
                   6368:     gm=vector(1,nlstate);
                   6369: 
                   6370:     for(theta=1; theta <=npar; theta++){
                   6371:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6372:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6373:       }
                   6374:       if(mobilavproj > 0 )
                   6375:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6376:       else
                   6377:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6378:       for(i=1;i<=nlstate;i++){
                   6379:        gp[i] = bprlim[i][i];
                   6380:        mgp[theta][i] = bprlim[i][i];
                   6381:       }
                   6382:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6383:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6384:        if(mobilavproj > 0 )
                   6385:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6386:        else
                   6387:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6388:       for(i=1;i<=nlstate;i++){
                   6389:        gm[i] = bprlim[i][i];
                   6390:        mgm[theta][i] = bprlim[i][i];
                   6391:       }
                   6392:       for(i=1;i<=nlstate;i++)
                   6393:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6394:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6395:     } /* End theta */
                   6396: 
                   6397:     trgradg =matrix(1,nlstate,1,npar);
                   6398: 
                   6399:     for(j=1; j<=nlstate;j++)
                   6400:       for(theta=1; theta <=npar; theta++)
                   6401:        trgradg[j][theta]=gradg[theta][j];
                   6402:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6403:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6404:     /*   for(j=1; j<=nlstate;j++){ */
                   6405:     /*         printf(" %d ",j); */
                   6406:     /*         for(theta=1; theta <=npar; theta++) */
                   6407:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6408:     /*         printf("\n "); */
                   6409:     /*   } */
                   6410:     /* } */
                   6411:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6412:     /*   printf("\n gradg %d ",(int)age); */
                   6413:     /*   for(j=1; j<=nlstate;j++){ */
                   6414:     /*         printf("%d ",j); */
                   6415:     /*         for(theta=1; theta <=npar; theta++) */
                   6416:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6417:     /*         printf("\n "); */
                   6418:     /*   } */
                   6419:     /* } */
                   6420: 
                   6421:     for(i=1;i<=nlstate;i++)
                   6422:       varbpl[i][(int)age] =0.;
                   6423:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6424:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6425:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6426:     }else{
                   6427:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6428:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6429:     }
                   6430:     for(i=1;i<=nlstate;i++)
                   6431:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6432: 
                   6433:     fprintf(ficresvbl,"%.0f ",age );
                   6434:     if(nresult >=1)
                   6435:       fprintf(ficresvbl,"%d ",nres );
                   6436:     for(i=1; i<=nlstate;i++)
                   6437:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6438:     fprintf(ficresvbl,"\n");
                   6439:     free_vector(gp,1,nlstate);
                   6440:     free_vector(gm,1,nlstate);
                   6441:     free_matrix(mgm,1,npar,1,nlstate);
                   6442:     free_matrix(mgp,1,npar,1,nlstate);
                   6443:     free_matrix(gradg,1,npar,1,nlstate);
                   6444:     free_matrix(trgradg,1,nlstate,1,npar);
                   6445:   } /* End age */
                   6446: 
                   6447:   free_vector(xp,1,npar);
                   6448:   free_matrix(doldm,1,nlstate,1,npar);
                   6449:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6450: 
                   6451: }
                   6452: 
                   6453: /************ Variance of one-step probabilities  ******************/
                   6454: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6455:  {
                   6456:    int i, j=0,  k1, l1, tj;
                   6457:    int k2, l2, j1,  z1;
                   6458:    int k=0, l;
                   6459:    int first=1, first1, first2;
                   6460:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6461:    double **dnewm,**doldm;
                   6462:    double *xp;
                   6463:    double *gp, *gm;
                   6464:    double **gradg, **trgradg;
                   6465:    double **mu;
                   6466:    double age, cov[NCOVMAX+1];
                   6467:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6468:    int theta;
                   6469:    char fileresprob[FILENAMELENGTH];
                   6470:    char fileresprobcov[FILENAMELENGTH];
                   6471:    char fileresprobcor[FILENAMELENGTH];
                   6472:    double ***varpij;
                   6473: 
                   6474:    strcpy(fileresprob,"PROB_"); 
                   6475:    strcat(fileresprob,fileres);
                   6476:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6477:      printf("Problem with resultfile: %s\n", fileresprob);
                   6478:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6479:    }
                   6480:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6481:    strcat(fileresprobcov,fileresu);
                   6482:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6483:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6484:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6485:    }
                   6486:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6487:    strcat(fileresprobcor,fileresu);
                   6488:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6489:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6490:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6491:    }
                   6492:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6493:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6494:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6495:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6496:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6497:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6498:    pstamp(ficresprob);
                   6499:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6500:    fprintf(ficresprob,"# Age");
                   6501:    pstamp(ficresprobcov);
                   6502:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6503:    fprintf(ficresprobcov,"# Age");
                   6504:    pstamp(ficresprobcor);
                   6505:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6506:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6507: 
                   6508: 
1.222     brouard  6509:    for(i=1; i<=nlstate;i++)
                   6510:      for(j=1; j<=(nlstate+ndeath);j++){
                   6511:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6512:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6513:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6514:      }  
                   6515:    /* fprintf(ficresprob,"\n");
                   6516:       fprintf(ficresprobcov,"\n");
                   6517:       fprintf(ficresprobcor,"\n");
                   6518:    */
                   6519:    xp=vector(1,npar);
                   6520:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6521:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6522:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6523:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6524:    first=1;
                   6525:    fprintf(ficgp,"\n# Routine varprob");
                   6526:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6527:    fprintf(fichtm,"\n");
                   6528: 
1.288     brouard  6529:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6530:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6531:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6532: and drawn. It helps understanding how is the covariance between two incidences.\
                   6533:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6534:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6535: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6536: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6537: standard deviations wide on each axis. <br>\
                   6538:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6539:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6540: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6541: 
1.222     brouard  6542:    cov[1]=1;
                   6543:    /* tj=cptcoveff; */
1.225     brouard  6544:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6545:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6546:    j1=0;
1.224     brouard  6547:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6548:      if  (cptcovn>0) {
                   6549:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6550:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6551:        fprintf(ficresprob, "**********\n#\n");
                   6552:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6553:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6554:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6555:                        
1.222     brouard  6556:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6557:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6558:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6559:                        
                   6560:                        
1.222     brouard  6561:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6562:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6563:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6564:                        
1.222     brouard  6565:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6566:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6567:        fprintf(ficresprobcor, "**********\n#");    
                   6568:        if(invalidvarcomb[j1]){
                   6569:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6570:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6571:         continue;
                   6572:        }
                   6573:      }
                   6574:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6575:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6576:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6577:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6578:      for (age=bage; age<=fage; age ++){ 
                   6579:        cov[2]=age;
                   6580:        if(nagesqr==1)
                   6581:         cov[3]= age*age;
                   6582:        for (k=1; k<=cptcovn;k++) {
                   6583:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6584:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6585:                                                                    * 1  1 1 1 1
                   6586:                                                                    * 2  2 1 1 1
                   6587:                                                                    * 3  1 2 1 1
                   6588:                                                                    */
                   6589:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6590:        }
                   6591:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6592:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6593:        for (k=1; k<=cptcovprod;k++)
                   6594:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6595:                        
                   6596:                        
1.222     brouard  6597:        for(theta=1; theta <=npar; theta++){
                   6598:         for(i=1; i<=npar; i++)
                   6599:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6600:                                
1.222     brouard  6601:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6602:                                
1.222     brouard  6603:         k=0;
                   6604:         for(i=1; i<= (nlstate); i++){
                   6605:           for(j=1; j<=(nlstate+ndeath);j++){
                   6606:             k=k+1;
                   6607:             gp[k]=pmmij[i][j];
                   6608:           }
                   6609:         }
1.220     brouard  6610:                                
1.222     brouard  6611:         for(i=1; i<=npar; i++)
                   6612:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6613:                                
1.222     brouard  6614:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6615:         k=0;
                   6616:         for(i=1; i<=(nlstate); i++){
                   6617:           for(j=1; j<=(nlstate+ndeath);j++){
                   6618:             k=k+1;
                   6619:             gm[k]=pmmij[i][j];
                   6620:           }
                   6621:         }
1.220     brouard  6622:                                
1.222     brouard  6623:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6624:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6625:        }
1.126     brouard  6626: 
1.222     brouard  6627:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6628:         for(theta=1; theta <=npar; theta++)
                   6629:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6630:                        
1.222     brouard  6631:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6632:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6633:                        
1.222     brouard  6634:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6635:                        
1.222     brouard  6636:        k=0;
                   6637:        for(i=1; i<=(nlstate); i++){
                   6638:         for(j=1; j<=(nlstate+ndeath);j++){
                   6639:           k=k+1;
                   6640:           mu[k][(int) age]=pmmij[i][j];
                   6641:         }
                   6642:        }
                   6643:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6644:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6645:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6646:                        
1.222     brouard  6647:        /*printf("\n%d ",(int)age);
                   6648:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6649:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6650:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6651:         }*/
1.220     brouard  6652:                        
1.222     brouard  6653:        fprintf(ficresprob,"\n%d ",(int)age);
                   6654:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6655:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6656:                        
1.222     brouard  6657:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6658:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6659:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6660:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6661:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6662:        }
                   6663:        i=0;
                   6664:        for (k=1; k<=(nlstate);k++){
                   6665:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6666:           i++;
                   6667:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6668:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6669:           for (j=1; j<=i;j++){
                   6670:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6671:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6672:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6673:           }
                   6674:         }
                   6675:        }/* end of loop for state */
                   6676:      } /* end of loop for age */
                   6677:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6678:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6679:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6680:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6681:     
                   6682:      /* Confidence intervalle of pij  */
                   6683:      /*
                   6684:        fprintf(ficgp,"\nunset parametric;unset label");
                   6685:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6686:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6687:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6688:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6689:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6690:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6691:      */
                   6692:                
                   6693:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6694:      first1=1;first2=2;
                   6695:      for (k2=1; k2<=(nlstate);k2++){
                   6696:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6697:         if(l2==k2) continue;
                   6698:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6699:         for (k1=1; k1<=(nlstate);k1++){
                   6700:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6701:             if(l1==k1) continue;
                   6702:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6703:             if(i<=j) continue;
                   6704:             for (age=bage; age<=fage; age ++){ 
                   6705:               if ((int)age %5==0){
                   6706:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6707:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6708:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6709:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6710:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6711:                 c12=cv12/sqrt(v1*v2);
                   6712:                 /* Computing eigen value of matrix of covariance */
                   6713:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6714:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6715:                 if ((lc2 <0) || (lc1 <0) ){
                   6716:                   if(first2==1){
                   6717:                     first1=0;
                   6718:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6719:                   }
                   6720:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6721:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6722:                   /* lc2=fabs(lc2); */
                   6723:                 }
1.220     brouard  6724:                                                                
1.222     brouard  6725:                 /* Eigen vectors */
1.280     brouard  6726:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6727:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6728:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6729:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6730:                 }else
                   6731:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6732:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6733:                 v21=(lc1-v1)/cv12*v11;
                   6734:                 v12=-v21;
                   6735:                 v22=v11;
                   6736:                 tnalp=v21/v11;
                   6737:                 if(first1==1){
                   6738:                   first1=0;
                   6739:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6740:                 }
                   6741:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6742:                 /*printf(fignu*/
                   6743:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6744:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6745:                 if(first==1){
                   6746:                   first=0;
                   6747:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6748:                   fprintf(ficgp,"\nset parametric;unset label");
                   6749:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6750:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6751:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6752:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6753: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6754:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6755:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6756:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6757:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6758:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6759:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6760:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6761:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6762:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6763:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6764:                 }else{
                   6765:                   first=0;
                   6766:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6767:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6768:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6769:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6770:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6771:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6772:                 }/* if first */
                   6773:               } /* age mod 5 */
                   6774:             } /* end loop age */
                   6775:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6776:             first=1;
                   6777:           } /*l12 */
                   6778:         } /* k12 */
                   6779:        } /*l1 */
                   6780:      }/* k1 */
                   6781:    }  /* loop on combination of covariates j1 */
                   6782:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6783:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6784:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6785:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6786:    free_vector(xp,1,npar);
                   6787:    fclose(ficresprob);
                   6788:    fclose(ficresprobcov);
                   6789:    fclose(ficresprobcor);
                   6790:    fflush(ficgp);
                   6791:    fflush(fichtmcov);
                   6792:  }
1.126     brouard  6793: 
                   6794: 
                   6795: /******************* Printing html file ***********/
1.201     brouard  6796: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6797:                  int lastpass, int stepm, int weightopt, char model[],\
                   6798:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6799:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.273     brouard  6800:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateproj1, double dateback1, \
                   6801:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateproj2, double dateback2){
1.237     brouard  6802:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6803: 
                   6804:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6805:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6806: </ul>");
1.237     brouard  6807:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6808: </ul>", model);
1.214     brouard  6809:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6810:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6811:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6812:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6813:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6814:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6815:    fprintf(fichtm,"\
                   6816:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6817:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6818:    fprintf(fichtm,"\
1.217     brouard  6819:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6820:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6821:    fprintf(fichtm,"\
1.288     brouard  6822:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6823:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6824:    fprintf(fichtm,"\
1.288     brouard  6825:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  6826:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6827:    fprintf(fichtm,"\
1.211     brouard  6828:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6829:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6830:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6831:    if(prevfcast==1){
                   6832:      fprintf(fichtm,"\
                   6833:  - Prevalence projections by age and states:                           \
1.201     brouard  6834:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6835:    }
1.126     brouard  6836: 
                   6837: 
1.225     brouard  6838:    m=pow(2,cptcoveff);
1.222     brouard  6839:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6840: 
1.264     brouard  6841:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6842: 
                   6843:    jj1=0;
                   6844: 
                   6845:    fprintf(fichtm," \n<ul>");
                   6846:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6847:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6848:      if(m != 1 && TKresult[nres]!= k1)
                   6849:        continue;
                   6850:      jj1++;
                   6851:      if (cptcovn > 0) {
                   6852:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6853:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6854:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6855:        }
                   6856:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6857:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6858:        }
                   6859:        fprintf(fichtm,"\">");
                   6860:        
                   6861:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6862:        fprintf(fichtm,"************ Results for covariates");
                   6863:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6864:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6865:        }
                   6866:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6867:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6868:        }
                   6869:        if(invalidvarcomb[k1]){
                   6870:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6871:         continue;
                   6872:        }
                   6873:        fprintf(fichtm,"</a></li>");
                   6874:      } /* cptcovn >0 */
                   6875:    }
                   6876:      fprintf(fichtm," \n</ul>");
                   6877: 
1.222     brouard  6878:    jj1=0;
1.237     brouard  6879: 
                   6880:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6881:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6882:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6883:        continue;
1.220     brouard  6884: 
1.222     brouard  6885:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6886:      jj1++;
                   6887:      if (cptcovn > 0) {
1.264     brouard  6888:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6889:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6890:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6891:        }
                   6892:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6893:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6894:        }
                   6895:        fprintf(fichtm,"\"</a>");
                   6896:  
1.222     brouard  6897:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6898:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6899:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6900:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6901:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6902:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6903:        }
1.237     brouard  6904:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6905:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6906:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6907:       }
                   6908:        
1.230     brouard  6909:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6910:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6911:        if(invalidvarcomb[k1]){
                   6912:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6913:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6914:         continue;
                   6915:        }
                   6916:      }
                   6917:      /* aij, bij */
1.259     brouard  6918:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6919: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6920:      /* Pij */
1.241     brouard  6921:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6922: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6923:      /* Quasi-incidences */
                   6924:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6925:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6926:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6927: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6928: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6929:      /* Survival functions (period) in state j */
                   6930:      for(cpt=1; cpt<=nlstate;cpt++){
1.241     brouard  6931:        fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6932: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6933:      }
                   6934:      /* State specific survival functions (period) */
                   6935:      for(cpt=1; cpt<=nlstate;cpt++){
                   6936:        fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
1.220     brouard  6937:  Or probability to survive in various states (1 to %d) being in state %d at different ages.    \
1.283     brouard  6938:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6939:      }
1.288     brouard  6940:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  6941:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6942:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6943: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6944:      }
                   6945:      if(backcast==1){
1.288     brouard  6946:        /* Backward prevalence in each health state */
1.222     brouard  6947:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6948:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6949: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6950:        }
1.217     brouard  6951:      }
1.222     brouard  6952:      if(prevfcast==1){
1.288     brouard  6953:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  6954:        for(cpt=1; cpt<=nlstate;cpt++){
1.288     brouard  6955:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.273     brouard  6956: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateproj1, dateproj2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6957:        }
                   6958:      }
1.268     brouard  6959:      if(backcast==1){
                   6960:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6961:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6962:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   6963:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   6964:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   6965: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6966:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  6967:        }
                   6968:      }
1.220     brouard  6969:         
1.222     brouard  6970:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6971:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6972: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6973:      }
                   6974:      /* } /\* end i1 *\/ */
                   6975:    }/* End k1 */
                   6976:    fprintf(fichtm,"</ul>");
1.126     brouard  6977: 
1.222     brouard  6978:    fprintf(fichtm,"\
1.126     brouard  6979: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6980:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6981:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6982: But because parameters are usually highly correlated (a higher incidence of disability \
                   6983: and a higher incidence of recovery can give very close observed transition) it might \
                   6984: be very useful to look not only at linear confidence intervals estimated from the \
                   6985: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6986: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6987: covariance matrix of the one-step probabilities. \
                   6988: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6989: 
1.222     brouard  6990:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6991:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6992:    fprintf(fichtm,"\
1.126     brouard  6993:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6994:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6995: 
1.222     brouard  6996:    fprintf(fichtm,"\
1.126     brouard  6997:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6998:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   6999:    fprintf(fichtm,"\
1.126     brouard  7000:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7001:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7002:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7003:    fprintf(fichtm,"\
1.126     brouard  7004:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7005:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7006:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7007:    fprintf(fichtm,"\
1.288     brouard  7008:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7009:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7010:    fprintf(fichtm,"\
1.128     brouard  7011:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7012:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7013:    fprintf(fichtm,"\
1.288     brouard  7014:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7015:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7016: 
                   7017: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7018: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7019: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7020: /*     <br>",fileres,fileres,fileres,fileres); */
                   7021: /*  else  */
                   7022: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7023:    fflush(fichtm);
                   7024:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7025: 
1.225     brouard  7026:    m=pow(2,cptcoveff);
1.222     brouard  7027:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7028: 
1.222     brouard  7029:    jj1=0;
1.237     brouard  7030: 
1.241     brouard  7031:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7032:    for(k1=1; k1<=m;k1++){
1.253     brouard  7033:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7034:        continue;
1.222     brouard  7035:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7036:      jj1++;
1.126     brouard  7037:      if (cptcovn > 0) {
                   7038:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7039:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7040:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7041:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7042:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7043:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7044:       }
                   7045: 
1.126     brouard  7046:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7047: 
1.222     brouard  7048:        if(invalidvarcomb[k1]){
                   7049:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7050:         continue;
                   7051:        }
1.126     brouard  7052:      }
                   7053:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7054:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7055: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7056: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7057:      }
                   7058:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7059: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7060: true period expectancies (those weighted with period prevalences are also\
                   7061:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7062:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7063: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7064:      /* } /\* end i1 *\/ */
                   7065:    }/* End k1 */
1.241     brouard  7066:   }/* End nres */
1.222     brouard  7067:    fprintf(fichtm,"</ul>");
                   7068:    fflush(fichtm);
1.126     brouard  7069: }
                   7070: 
                   7071: /******************* Gnuplot file **************/
1.270     brouard  7072: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7073: 
                   7074:   char dirfileres[132],optfileres[132];
1.264     brouard  7075:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7076:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7077:   int lv=0, vlv=0, kl=0;
1.130     brouard  7078:   int ng=0;
1.201     brouard  7079:   int vpopbased;
1.223     brouard  7080:   int ioffset; /* variable offset for columns */
1.270     brouard  7081:   int iyearc=1; /* variable column for year of projection  */
                   7082:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7083:   int nres=0; /* Index of resultline */
1.266     brouard  7084:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7085: 
1.126     brouard  7086: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7087: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7088: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7089: /*   } */
                   7090: 
                   7091:   /*#ifdef windows */
                   7092:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7093:   /*#endif */
1.225     brouard  7094:   m=pow(2,cptcoveff);
1.126     brouard  7095: 
1.274     brouard  7096:   /* diagram of the model */
                   7097:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7098:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7099:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7100:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7101: 
                   7102:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7103:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7104:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7105:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7106:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7107:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7108:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7109: 
1.202     brouard  7110:   /* Contribution to likelihood */
                   7111:   /* Plot the probability implied in the likelihood */
1.223     brouard  7112:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7113:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7114:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7115:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7116: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7117:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7118: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7119:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7120:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7121:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7122:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7123:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7124:   for (i=1; i<= nlstate ; i ++) {
                   7125:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7126:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7127:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7128:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7129:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7130:     }
                   7131:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7132:   }
                   7133:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7134:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7135:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7136:   fprintf(ficgp,"\nset out;unset log\n");
                   7137:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7138: 
1.126     brouard  7139:   strcpy(dirfileres,optionfilefiname);
                   7140:   strcpy(optfileres,"vpl");
1.223     brouard  7141:   /* 1eme*/
1.238     brouard  7142:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7143:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7144:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7145:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7146:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7147:          continue;
                   7148:        /* We are interested in selected combination by the resultline */
1.246     brouard  7149:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7150:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7151:        strcpy(gplotlabel,"(");
1.238     brouard  7152:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7153:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7154:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7155:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7156:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7157:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7158:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7159:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7160:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7161:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7162:        }
                   7163:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7164:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7165:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7166:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7167:        }
                   7168:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7169:        /* printf("\n#\n"); */
1.238     brouard  7170:        fprintf(ficgp,"\n#\n");
                   7171:        if(invalidvarcomb[k1]){
1.260     brouard  7172:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7173:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7174:          continue;
                   7175:        }
1.235     brouard  7176:       
1.241     brouard  7177:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7178:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7179:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7180:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7181:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7182:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7183:       /* k1-1 error should be nres-1*/
1.238     brouard  7184:        for (i=1; i<= nlstate ; i ++) {
                   7185:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7186:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7187:        }
1.288     brouard  7188:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7189:        for (i=1; i<= nlstate ; i ++) {
                   7190:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7191:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7192:        } 
1.260     brouard  7193:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7194:        for (i=1; i<= nlstate ; i ++) {
                   7195:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7196:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7197:        }  
1.265     brouard  7198:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7199:        
                   7200:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7201:         if(cptcoveff ==0){
1.271     brouard  7202:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7203:        }else{
                   7204:          kl=0;
                   7205:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7206:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7207:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7208:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7209:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7210:            vlv= nbcode[Tvaraff[k]][lv];
                   7211:            kl++;
                   7212:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7213:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7214:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7215:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7216:            if(k==cptcoveff){
                   7217:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7218:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7219:            }else{
                   7220:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7221:              kl++;
                   7222:            }
                   7223:          } /* end covariate */
                   7224:        } /* end if no covariate */
                   7225: 
1.238     brouard  7226:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7227:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7228:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7229:          if(cptcoveff ==0){
1.245     brouard  7230:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7231:          }else{
                   7232:            kl=0;
                   7233:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7234:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7235:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7236:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7237:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7238:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7239:              kl++;
1.238     brouard  7240:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7241:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7242:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7243:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7244:              if(k==cptcoveff){
1.245     brouard  7245:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7246:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7247:              }else{
                   7248:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7249:                kl++;
                   7250:              }
                   7251:            } /* end covariate */
                   7252:          } /* end if no covariate */
1.268     brouard  7253:          if(backcast == 1){
                   7254:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7255:            /* k1-1 error should be nres-1*/
                   7256:            for (i=1; i<= nlstate ; i ++) {
                   7257:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7258:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7259:            }
1.271     brouard  7260:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7261:            for (i=1; i<= nlstate ; i ++) {
                   7262:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7263:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7264:            } 
1.276     brouard  7265:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7266:            for (i=1; i<= nlstate ; i ++) {
                   7267:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7268:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7269:            } 
1.274     brouard  7270:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7271:          } /* end if backprojcast */
1.238     brouard  7272:        } /* end if backcast */
1.276     brouard  7273:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7274:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7275:       } /* nres */
1.201     brouard  7276:     } /* k1 */
                   7277:   } /* cpt */
1.235     brouard  7278: 
                   7279:   
1.126     brouard  7280:   /*2 eme*/
1.238     brouard  7281:   for (k1=1; k1<= m ; k1 ++){  
                   7282:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7283:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7284:        continue;
                   7285:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7286:       strcpy(gplotlabel,"(");
1.238     brouard  7287:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7288:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7289:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7290:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7291:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7292:        vlv= nbcode[Tvaraff[k]][lv];
                   7293:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7294:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7295:       }
1.237     brouard  7296:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7297:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7298:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7299:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7300:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7301:       }
1.264     brouard  7302:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7303:       fprintf(ficgp,"\n#\n");
1.223     brouard  7304:       if(invalidvarcomb[k1]){
                   7305:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7306:        continue;
                   7307:       }
1.219     brouard  7308:                        
1.241     brouard  7309:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7310:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7311:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7312:        if(vpopbased==0){
1.238     brouard  7313:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7314:        }else
1.238     brouard  7315:          fprintf(ficgp,"\nreplot ");
                   7316:        for (i=1; i<= nlstate+1 ; i ++) {
                   7317:          k=2*i;
1.261     brouard  7318:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7319:          for (j=1; j<= nlstate+1 ; j ++) {
                   7320:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7321:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7322:          }   
                   7323:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7324:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7325:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7326:          for (j=1; j<= nlstate+1 ; j ++) {
                   7327:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7328:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7329:          }   
                   7330:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7331:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7332:          for (j=1; j<= nlstate+1 ; j ++) {
                   7333:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7334:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7335:          }   
                   7336:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7337:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7338:        } /* state */
                   7339:       } /* vpopbased */
1.264     brouard  7340:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7341:     } /* end nres */
                   7342:   } /* k1 end 2 eme*/
                   7343:        
                   7344:        
                   7345:   /*3eme*/
                   7346:   for (k1=1; k1<= m ; k1 ++){
                   7347:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7348:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7349:        continue;
                   7350: 
                   7351:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7352:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7353:        strcpy(gplotlabel,"(");
1.238     brouard  7354:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7355:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7356:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7357:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7358:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7359:          vlv= nbcode[Tvaraff[k]][lv];
                   7360:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7361:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7362:        }
                   7363:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7364:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7365:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7366:        }       
1.264     brouard  7367:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7368:        fprintf(ficgp,"\n#\n");
                   7369:        if(invalidvarcomb[k1]){
                   7370:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7371:          continue;
                   7372:        }
                   7373:                        
                   7374:        /*       k=2+nlstate*(2*cpt-2); */
                   7375:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7376:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7377:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7378:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7379: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7380:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7381:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7382:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7383:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7384:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7385:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7386:                                
1.238     brouard  7387:        */
                   7388:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7389:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7390:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7391:                                
1.238     brouard  7392:        } 
1.261     brouard  7393:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7394:       }
1.264     brouard  7395:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7396:     } /* end nres */
                   7397:   } /* end kl 3eme */
1.126     brouard  7398:   
1.223     brouard  7399:   /* 4eme */
1.201     brouard  7400:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7401:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7402:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7403:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7404:        continue;
1.238     brouard  7405:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7406:        strcpy(gplotlabel,"(");
1.238     brouard  7407:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7408:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7409:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7410:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7411:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7412:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7413:          vlv= nbcode[Tvaraff[k]][lv];
                   7414:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7415:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7416:        }
                   7417:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7418:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7419:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7420:        }       
1.264     brouard  7421:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7422:        fprintf(ficgp,"\n#\n");
                   7423:        if(invalidvarcomb[k1]){
                   7424:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7425:          continue;
1.223     brouard  7426:        }
1.238     brouard  7427:       
1.241     brouard  7428:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7429:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7430:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7431: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7432:        k=3;
                   7433:        for (i=1; i<= nlstate ; i ++){
                   7434:          if(i==1){
                   7435:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7436:          }else{
                   7437:            fprintf(ficgp,", '' ");
                   7438:          }
                   7439:          l=(nlstate+ndeath)*(i-1)+1;
                   7440:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7441:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7442:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7443:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7444:        } /* nlstate */
1.264     brouard  7445:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7446:       } /* end cpt state*/ 
                   7447:     } /* end nres */
                   7448:   } /* end covariate k1 */  
                   7449: 
1.220     brouard  7450: /* 5eme */
1.201     brouard  7451:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7452:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7453:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7454:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7455:        continue;
1.238     brouard  7456:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7457:        strcpy(gplotlabel,"(");
1.238     brouard  7458:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7459:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7460:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7461:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7462:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7463:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7464:          vlv= nbcode[Tvaraff[k]][lv];
                   7465:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7466:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7467:        }
                   7468:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7469:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7470:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7471:        }       
1.264     brouard  7472:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7473:        fprintf(ficgp,"\n#\n");
                   7474:        if(invalidvarcomb[k1]){
                   7475:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7476:          continue;
                   7477:        }
1.227     brouard  7478:       
1.241     brouard  7479:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7480:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7481:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7482: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7483:        k=3;
                   7484:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7485:          if(j==1)
                   7486:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7487:          else
                   7488:            fprintf(ficgp,", '' ");
                   7489:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7490:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7491:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7492:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7493:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7494:        } /* nlstate */
                   7495:        fprintf(ficgp,", '' ");
                   7496:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7497:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7498:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7499:          if(j < nlstate)
                   7500:            fprintf(ficgp,"$%d +",k+l);
                   7501:          else
                   7502:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7503:        }
1.264     brouard  7504:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7505:       } /* end cpt state*/ 
                   7506:     } /* end covariate */  
                   7507:   } /* end nres */
1.227     brouard  7508:   
1.220     brouard  7509: /* 6eme */
1.202     brouard  7510:   /* CV preval stable (period) for each covariate */
1.237     brouard  7511:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7512:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7513:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7514:       continue;
1.255     brouard  7515:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7516:       strcpy(gplotlabel,"(");      
1.288     brouard  7517:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7518:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7519:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7520:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7521:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7522:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7523:        vlv= nbcode[Tvaraff[k]][lv];
                   7524:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7525:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7526:       }
1.237     brouard  7527:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7528:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7529:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7530:       }        
1.264     brouard  7531:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7532:       fprintf(ficgp,"\n#\n");
1.223     brouard  7533:       if(invalidvarcomb[k1]){
1.227     brouard  7534:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7535:        continue;
1.223     brouard  7536:       }
1.227     brouard  7537:       
1.241     brouard  7538:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7539:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7540:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7541: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7542:       k=3; /* Offset */
1.255     brouard  7543:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7544:        if(i==1)
                   7545:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7546:        else
                   7547:          fprintf(ficgp,", '' ");
1.255     brouard  7548:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7549:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7550:        for (j=2; j<= nlstate ; j ++)
                   7551:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7552:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7553:       } /* nlstate */
1.264     brouard  7554:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7555:     } /* end cpt state*/ 
                   7556:   } /* end covariate */  
1.227     brouard  7557:   
                   7558:   
1.220     brouard  7559: /* 7eme */
1.218     brouard  7560:   if(backcast == 1){
1.288     brouard  7561:     /* CV backward prevalence  for each covariate */
1.237     brouard  7562:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7563:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7564:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7565:        continue;
1.268     brouard  7566:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7567:        strcpy(gplotlabel,"(");      
1.288     brouard  7568:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7569:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7570:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7571:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7572:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7573:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7574:          vlv= nbcode[Tvaraff[k]][lv];
                   7575:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7576:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7577:        }
1.237     brouard  7578:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7579:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7580:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7581:        }       
1.264     brouard  7582:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7583:        fprintf(ficgp,"\n#\n");
                   7584:        if(invalidvarcomb[k1]){
                   7585:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7586:          continue;
                   7587:        }
                   7588:        
1.241     brouard  7589:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7590:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7591:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7592: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7593:        k=3; /* Offset */
1.268     brouard  7594:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7595:          if(i==1)
                   7596:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7597:          else
                   7598:            fprintf(ficgp,", '' ");
                   7599:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7600:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7601:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7602:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7603:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7604:          /* for (j=2; j<= nlstate ; j ++) */
                   7605:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7606:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7607:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7608:        } /* nlstate */
1.264     brouard  7609:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7610:       } /* end cpt state*/ 
                   7611:     } /* end covariate */  
                   7612:   } /* End if backcast */
                   7613:   
1.223     brouard  7614:   /* 8eme */
1.218     brouard  7615:   if(prevfcast==1){
1.288     brouard  7616:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7617:     
1.237     brouard  7618:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7619:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7620:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7621:        continue;
1.211     brouard  7622:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7623:        strcpy(gplotlabel,"(");      
1.288     brouard  7624:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7625:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7626:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7627:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7628:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7629:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7630:          vlv= nbcode[Tvaraff[k]][lv];
                   7631:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7632:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7633:        }
1.237     brouard  7634:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7635:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7636:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7637:        }       
1.264     brouard  7638:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7639:        fprintf(ficgp,"\n#\n");
                   7640:        if(invalidvarcomb[k1]){
                   7641:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7642:          continue;
                   7643:        }
                   7644:        
                   7645:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7646:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7647:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7648:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7649: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7650: 
                   7651:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7652:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7653:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7654:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7655:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7656:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7657:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7658:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7659:          if(i==istart){
1.227     brouard  7660:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7661:          }else{
                   7662:            fprintf(ficgp,",\\\n '' ");
                   7663:          }
                   7664:          if(cptcoveff ==0){ /* No covariate */
                   7665:            ioffset=2; /* Age is in 2 */
                   7666:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7667:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7668:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7669:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7670:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7671:            if(i==nlstate+1){
1.270     brouard  7672:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7673:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7674:              fprintf(ficgp,",\\\n '' ");
                   7675:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7676:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7677:                     offyear,                           \
1.268     brouard  7678:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7679:            }else
1.227     brouard  7680:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7681:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7682:          }else{ /* more than 2 covariates */
1.270     brouard  7683:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7684:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7685:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7686:            iyearc=ioffset-1;
                   7687:            iagec=ioffset;
1.227     brouard  7688:            fprintf(ficgp," u %d:(",ioffset); 
                   7689:            kl=0;
                   7690:            strcpy(gplotcondition,"(");
                   7691:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7692:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7693:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7694:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7695:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7696:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7697:              kl++;
                   7698:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7699:              kl++;
                   7700:              if(k <cptcoveff && cptcoveff>1)
                   7701:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7702:            }
                   7703:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7704:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7705:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7706:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7707:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7708:            if(i==nlstate+1){
1.270     brouard  7709:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7710:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7711:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7712:              fprintf(ficgp," u %d:(",iagec); 
                   7713:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7714:                      iyearc, iagec, offyear,                           \
                   7715:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7716: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7717:            }else{
                   7718:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7719:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7720:            }
                   7721:          } /* end if covariate */
                   7722:        } /* nlstate */
1.264     brouard  7723:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7724:       } /* end cpt state*/
                   7725:     } /* end covariate */
                   7726:   } /* End if prevfcast */
1.227     brouard  7727:   
1.268     brouard  7728:   if(backcast==1){
                   7729:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7730:     
                   7731:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7732:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7733:       if(m != 1 && TKresult[nres]!= k1)
                   7734:        continue;
                   7735:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7736:        strcpy(gplotlabel,"(");      
                   7737:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7738:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7739:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7740:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7741:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7742:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7743:          vlv= nbcode[Tvaraff[k]][lv];
                   7744:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7745:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7746:        }
                   7747:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7748:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7749:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7750:        }       
                   7751:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7752:        fprintf(ficgp,"\n#\n");
                   7753:        if(invalidvarcomb[k1]){
                   7754:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7755:          continue;
                   7756:        }
                   7757:        
                   7758:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7759:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7760:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7761:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7762: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7763: 
                   7764:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7765:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7766:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7767:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7768:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7769:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7770:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7771:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7772:          if(i==istart){
                   7773:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7774:          }else{
                   7775:            fprintf(ficgp,",\\\n '' ");
                   7776:          }
                   7777:          if(cptcoveff ==0){ /* No covariate */
                   7778:            ioffset=2; /* Age is in 2 */
                   7779:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7780:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7781:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7782:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7783:            fprintf(ficgp," u %d:(", ioffset); 
                   7784:            if(i==nlstate+1){
1.270     brouard  7785:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7786:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7787:              fprintf(ficgp,",\\\n '' ");
                   7788:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7789:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7790:                     offbyear,                          \
                   7791:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7792:            }else
                   7793:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7794:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7795:          }else{ /* more than 2 covariates */
1.270     brouard  7796:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7797:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7798:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7799:            iyearc=ioffset-1;
                   7800:            iagec=ioffset;
1.268     brouard  7801:            fprintf(ficgp," u %d:(",ioffset); 
                   7802:            kl=0;
                   7803:            strcpy(gplotcondition,"(");
                   7804:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7805:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7806:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7807:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7808:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7809:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7810:              kl++;
                   7811:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7812:              kl++;
                   7813:              if(k <cptcoveff && cptcoveff>1)
                   7814:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7815:            }
                   7816:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7817:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7818:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7819:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7820:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7821:            if(i==nlstate+1){
1.270     brouard  7822:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7823:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7824:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7825:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7826:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7827:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7828:                      iyearc,iagec,offbyear,                            \
                   7829:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7830: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7831:            }else{
                   7832:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7833:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7834:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7835:            }
                   7836:          } /* end if covariate */
                   7837:        } /* nlstate */
                   7838:        fprintf(ficgp,"\nset out; unset label;\n");
                   7839:       } /* end cpt state*/
                   7840:     } /* end covariate */
                   7841:   } /* End if backcast */
                   7842:   
1.227     brouard  7843:   
1.238     brouard  7844:   /* 9eme writing MLE parameters */
                   7845:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7846:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7847:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7848:     for(k=1; k <=(nlstate+ndeath); k++){
                   7849:       if (k != i) {
1.227     brouard  7850:        fprintf(ficgp,"#   current state %d\n",k);
                   7851:        for(j=1; j <=ncovmodel; j++){
                   7852:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7853:          jk++; 
                   7854:        }
                   7855:        fprintf(ficgp,"\n");
1.126     brouard  7856:       }
                   7857:     }
1.223     brouard  7858:   }
1.187     brouard  7859:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7860:   
1.145     brouard  7861:   /*goto avoid;*/
1.238     brouard  7862:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7863:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7864:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7865:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7866:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7867:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7868:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7869:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7870:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7871:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7872:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7873:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7874:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7875:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7876:   fprintf(ficgp,"#\n");
1.223     brouard  7877:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7878:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7879:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7880:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7881:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7882:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7883:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7884:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7885:        continue;
1.264     brouard  7886:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7887:       strcpy(gplotlabel,"(");
1.276     brouard  7888:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  7889:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7890:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7891:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7892:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7893:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7894:        vlv= nbcode[Tvaraff[k]][lv];
                   7895:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7896:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7897:       }
1.237     brouard  7898:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7899:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7900:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7901:       }        
1.264     brouard  7902:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7903:       fprintf(ficgp,"\n#\n");
1.264     brouard  7904:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  7905:       fprintf(ficgp,"\nset key outside ");
                   7906:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   7907:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7908:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7909:       if (ng==1){
                   7910:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7911:        fprintf(ficgp,"\nunset log y");
                   7912:       }else if (ng==2){
                   7913:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7914:        fprintf(ficgp,"\nset log y");
                   7915:       }else if (ng==3){
                   7916:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7917:        fprintf(ficgp,"\nset log y");
                   7918:       }else
                   7919:        fprintf(ficgp,"\nunset title ");
                   7920:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7921:       i=1;
                   7922:       for(k2=1; k2<=nlstate; k2++) {
                   7923:        k3=i;
                   7924:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7925:          if (k != k2){
                   7926:            switch( ng) {
                   7927:            case 1:
                   7928:              if(nagesqr==0)
                   7929:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7930:              else /* nagesqr =1 */
                   7931:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7932:              break;
                   7933:            case 2: /* ng=2 */
                   7934:              if(nagesqr==0)
                   7935:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7936:              else /* nagesqr =1 */
                   7937:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7938:              break;
                   7939:            case 3:
                   7940:              if(nagesqr==0)
                   7941:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7942:              else /* nagesqr =1 */
                   7943:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7944:              break;
                   7945:            }
                   7946:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7947:            ijp=1; /* product no age */
                   7948:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7949:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7950:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7951:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7952:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7953:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7954:                    if(DummyV[j]==0){
                   7955:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7956:                    }else{ /* quantitative */
                   7957:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7958:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7959:                    }
                   7960:                    ij++;
1.237     brouard  7961:                  }
1.268     brouard  7962:                } 
                   7963:              }else if(cptcovprod >0){
                   7964:                if(j==Tprod[ijp]) { /* */ 
                   7965:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7966:                  if(ijp <=cptcovprod) { /* Product */
                   7967:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7968:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7969:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7970:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7971:                      }else{ /* Vn is dummy and Vm is quanti */
                   7972:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7973:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7974:                      }
                   7975:                    }else{ /* Vn*Vm Vn is quanti */
                   7976:                      if(DummyV[Tvard[ijp][2]]==0){
                   7977:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7978:                      }else{ /* Both quanti */
                   7979:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7980:                      }
1.237     brouard  7981:                    }
1.268     brouard  7982:                    ijp++;
1.237     brouard  7983:                  }
1.268     brouard  7984:                } /* end Tprod */
1.237     brouard  7985:              } else{  /* simple covariate */
1.264     brouard  7986:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7987:                if(Dummy[j]==0){
                   7988:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7989:                }else{ /* quantitative */
                   7990:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7991:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7992:                }
1.237     brouard  7993:              } /* end simple */
                   7994:            } /* end j */
1.223     brouard  7995:          }else{
                   7996:            i=i-ncovmodel;
                   7997:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   7998:              fprintf(ficgp," (1.");
                   7999:          }
1.227     brouard  8000:          
1.223     brouard  8001:          if(ng != 1){
                   8002:            fprintf(ficgp,")/(1");
1.227     brouard  8003:            
1.264     brouard  8004:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8005:              if(nagesqr==0)
1.264     brouard  8006:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8007:              else /* nagesqr =1 */
1.264     brouard  8008:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8009:               
1.223     brouard  8010:              ij=1;
                   8011:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8012:                 if(cptcovage >0){ 
                   8013:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8014:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8015:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8016:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8017:                       ij++;
                   8018:                     }
                   8019:                   }
                   8020:                 }else
                   8021:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8022:              }
                   8023:              fprintf(ficgp,")");
                   8024:            }
                   8025:            fprintf(ficgp,")");
                   8026:            if(ng ==2)
1.276     brouard  8027:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8028:            else /* ng= 3 */
1.276     brouard  8029:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8030:          }else{ /* end ng <> 1 */
                   8031:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8032:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8033:          }
                   8034:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8035:            fprintf(ficgp,",");
                   8036:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8037:            fprintf(ficgp,",");
                   8038:          i=i+ncovmodel;
                   8039:        } /* end k */
                   8040:       } /* end k2 */
1.276     brouard  8041:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8042:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8043:     } /* end k1 */
1.223     brouard  8044:   } /* end ng */
                   8045:   /* avoid: */
                   8046:   fflush(ficgp); 
1.126     brouard  8047: }  /* end gnuplot */
                   8048: 
                   8049: 
                   8050: /*************** Moving average **************/
1.219     brouard  8051: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8052:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8053:    
1.222     brouard  8054:    int i, cpt, cptcod;
                   8055:    int modcovmax =1;
                   8056:    int mobilavrange, mob;
                   8057:    int iage=0;
1.288     brouard  8058:    int firstA1=0, firstA2=0;
1.222     brouard  8059: 
1.266     brouard  8060:    double sum=0., sumr=0.;
1.222     brouard  8061:    double age;
1.266     brouard  8062:    double *sumnewp, *sumnewm, *sumnewmr;
                   8063:    double *agemingood, *agemaxgood; 
                   8064:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8065:   
                   8066:   
1.278     brouard  8067:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8068:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8069: 
                   8070:    sumnewp = vector(1,ncovcombmax);
                   8071:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8072:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8073:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8074:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8075:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8076:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8077: 
                   8078:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8079:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8080:      sumnewp[cptcod]=0.;
1.266     brouard  8081:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8082:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8083:    }
                   8084:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8085:   
1.266     brouard  8086:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8087:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8088:      else mobilavrange=mobilav;
                   8089:      for (age=bage; age<=fage; age++)
                   8090:        for (i=1; i<=nlstate;i++)
                   8091:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8092:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8093:      /* We keep the original values on the extreme ages bage, fage and for 
                   8094:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8095:        we use a 5 terms etc. until the borders are no more concerned. 
                   8096:      */ 
                   8097:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8098:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8099:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8100:           sumnewm[cptcod]=0.;
                   8101:           for (i=1; i<=nlstate;i++){
1.222     brouard  8102:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8103:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8104:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8105:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8106:             }
                   8107:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8108:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8109:           } /* end i */
                   8110:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8111:         } /* end cptcod */
1.222     brouard  8112:        }/* end age */
                   8113:      }/* end mob */
1.266     brouard  8114:    }else{
                   8115:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8116:      return -1;
1.266     brouard  8117:    }
                   8118: 
                   8119:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8120:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8121:      if(invalidvarcomb[cptcod]){
                   8122:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8123:        continue;
                   8124:      }
1.219     brouard  8125: 
1.266     brouard  8126:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8127:        sumnewm[cptcod]=0.;
                   8128:        sumnewmr[cptcod]=0.;
                   8129:        for (i=1; i<=nlstate;i++){
                   8130:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8131:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8132:        }
                   8133:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8134:         agemingoodr[cptcod]=age;
                   8135:        }
                   8136:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8137:           agemingood[cptcod]=age;
                   8138:        }
                   8139:      } /* age */
                   8140:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8141:        sumnewm[cptcod]=0.;
1.266     brouard  8142:        sumnewmr[cptcod]=0.;
1.222     brouard  8143:        for (i=1; i<=nlstate;i++){
                   8144:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8145:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8146:        }
                   8147:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8148:         agemaxgoodr[cptcod]=age;
1.222     brouard  8149:        }
                   8150:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8151:         agemaxgood[cptcod]=age;
                   8152:        }
                   8153:      } /* age */
                   8154:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8155:      /* but they will change */
1.288     brouard  8156:      firstA1=0;firstA2=0;
1.266     brouard  8157:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8158:        sumnewm[cptcod]=0.;
                   8159:        sumnewmr[cptcod]=0.;
                   8160:        for (i=1; i<=nlstate;i++){
                   8161:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8162:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8163:        }
                   8164:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8165:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8166:           agemaxgoodr[cptcod]=age;  /* age min */
                   8167:           for (i=1; i<=nlstate;i++)
                   8168:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8169:         }else{ /* bad we change the value with the values of good ages */
                   8170:           for (i=1; i<=nlstate;i++){
                   8171:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8172:           } /* i */
                   8173:         } /* end bad */
                   8174:        }else{
                   8175:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8176:           agemaxgood[cptcod]=age;
                   8177:         }else{ /* bad we change the value with the values of good ages */
                   8178:           for (i=1; i<=nlstate;i++){
                   8179:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8180:           } /* i */
                   8181:         } /* end bad */
                   8182:        }/* end else */
                   8183:        sum=0.;sumr=0.;
                   8184:        for (i=1; i<=nlstate;i++){
                   8185:         sum+=mobaverage[(int)age][i][cptcod];
                   8186:         sumr+=probs[(int)age][i][cptcod];
                   8187:        }
                   8188:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8189:         if(!firstA1){
                   8190:           firstA1=1;
                   8191:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8192:         }
                   8193:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8194:        } /* end bad */
                   8195:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8196:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8197:         if(!firstA2){
                   8198:           firstA2=1;
                   8199:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8200:         }
                   8201:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8202:        } /* end bad */
                   8203:      }/* age */
1.266     brouard  8204: 
                   8205:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8206:        sumnewm[cptcod]=0.;
1.266     brouard  8207:        sumnewmr[cptcod]=0.;
1.222     brouard  8208:        for (i=1; i<=nlstate;i++){
                   8209:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8210:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8211:        } 
                   8212:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8213:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8214:           agemingoodr[cptcod]=age;
                   8215:           for (i=1; i<=nlstate;i++)
                   8216:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8217:         }else{ /* bad we change the value with the values of good ages */
                   8218:           for (i=1; i<=nlstate;i++){
                   8219:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8220:           } /* i */
                   8221:         } /* end bad */
                   8222:        }else{
                   8223:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8224:           agemingood[cptcod]=age;
                   8225:         }else{ /* bad */
                   8226:           for (i=1; i<=nlstate;i++){
                   8227:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8228:           } /* i */
                   8229:         } /* end bad */
                   8230:        }/* end else */
                   8231:        sum=0.;sumr=0.;
                   8232:        for (i=1; i<=nlstate;i++){
                   8233:         sum+=mobaverage[(int)age][i][cptcod];
                   8234:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8235:        }
1.266     brouard  8236:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8237:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8238:        } /* end bad */
                   8239:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8240:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8241:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8242:        } /* end bad */
                   8243:      }/* age */
1.266     brouard  8244: 
1.222     brouard  8245:                
                   8246:      for (age=bage; age<=fage; age++){
1.235     brouard  8247:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8248:        sumnewp[cptcod]=0.;
                   8249:        sumnewm[cptcod]=0.;
                   8250:        for (i=1; i<=nlstate;i++){
                   8251:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8252:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8253:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8254:        }
                   8255:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8256:      }
                   8257:      /* printf("\n"); */
                   8258:      /* } */
1.266     brouard  8259: 
1.222     brouard  8260:      /* brutal averaging */
1.266     brouard  8261:      /* for (i=1; i<=nlstate;i++){ */
                   8262:      /*   for (age=1; age<=bage; age++){ */
                   8263:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8264:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8265:      /*   }     */
                   8266:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8267:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8268:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8269:      /*   } */
                   8270:      /* } /\* end i status *\/ */
                   8271:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8272:      /*   for (age=1; age<=AGESUP; age++){ */
                   8273:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8274:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8275:      /*   } */
                   8276:      /* } */
1.222     brouard  8277:    }/* end cptcod */
1.266     brouard  8278:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8279:    free_vector(agemaxgood,1, ncovcombmax);
                   8280:    free_vector(agemingood,1, ncovcombmax);
                   8281:    free_vector(agemingoodr,1, ncovcombmax);
                   8282:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8283:    free_vector(sumnewm,1, ncovcombmax);
                   8284:    free_vector(sumnewp,1, ncovcombmax);
                   8285:    return 0;
                   8286:  }/* End movingaverage */
1.218     brouard  8287:  
1.126     brouard  8288: 
                   8289: /************** Forecasting ******************/
1.269     brouard  8290:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8291:   /* proj1, year, month, day of starting projection 
                   8292:      agemin, agemax range of age
                   8293:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8294:      anproj2 year of en of projection (same day and month as proj1).
                   8295:   */
1.267     brouard  8296:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8297:   double agec; /* generic age */
                   8298:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8299:   double *popeffectif,*popcount;
                   8300:   double ***p3mat;
1.218     brouard  8301:   /* double ***mobaverage; */
1.126     brouard  8302:   char fileresf[FILENAMELENGTH];
                   8303: 
                   8304:   agelim=AGESUP;
1.211     brouard  8305:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8306:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8307:      We still use firstpass and lastpass as another selection.
                   8308:   */
1.214     brouard  8309:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8310:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8311:  
1.201     brouard  8312:   strcpy(fileresf,"F_"); 
                   8313:   strcat(fileresf,fileresu);
1.126     brouard  8314:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8315:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8316:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8317:   }
1.235     brouard  8318:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8319:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8320: 
1.225     brouard  8321:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8322: 
                   8323: 
                   8324:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8325:   if (stepm<=12) stepsize=1;
                   8326:   if(estepm < stepm){
                   8327:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8328:   }
1.270     brouard  8329:   else{
                   8330:     hstepm=estepm;   
                   8331:   }
                   8332:   if(estepm > stepm){ /* Yes every two year */
                   8333:     stepsize=2;
                   8334:   }
1.126     brouard  8335: 
                   8336:   hstepm=hstepm/stepm; 
                   8337:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8338:                                fractional in yp1 */
                   8339:   anprojmean=yp;
                   8340:   yp2=modf((yp1*12),&yp);
                   8341:   mprojmean=yp;
                   8342:   yp1=modf((yp2*30.5),&yp);
                   8343:   jprojmean=yp;
                   8344:   if(jprojmean==0) jprojmean=1;
                   8345:   if(mprojmean==0) jprojmean=1;
                   8346: 
1.227     brouard  8347:   i1=pow(2,cptcoveff);
1.126     brouard  8348:   if (cptcovn < 1){i1=1;}
                   8349:   
                   8350:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8351:   
                   8352:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8353:   
1.126     brouard  8354: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8355:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8356:   for(k=1; k<=i1;k++){
1.253     brouard  8357:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8358:       continue;
1.227     brouard  8359:     if(invalidvarcomb[k]){
                   8360:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8361:       continue;
                   8362:     }
                   8363:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8364:     for(j=1;j<=cptcoveff;j++) {
                   8365:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8366:     }
1.235     brouard  8367:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8368:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8369:     }
1.227     brouard  8370:     fprintf(ficresf," yearproj age");
                   8371:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8372:       for(i=1; i<=nlstate;i++)               
                   8373:        fprintf(ficresf," p%d%d",i,j);
                   8374:       fprintf(ficresf," wp.%d",j);
                   8375:     }
                   8376:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8377:       fprintf(ficresf,"\n");
                   8378:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8379:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8380:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8381:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8382:        nhstepm = nhstepm/hstepm; 
                   8383:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8384:        oldm=oldms;savm=savms;
1.268     brouard  8385:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8386:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8387:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8388:        for (h=0; h<=nhstepm; h++){
                   8389:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8390:            break;
                   8391:          }
                   8392:        }
                   8393:        fprintf(ficresf,"\n");
                   8394:        for(j=1;j<=cptcoveff;j++) 
                   8395:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8396:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8397:        
                   8398:        for(j=1; j<=nlstate+ndeath;j++) {
                   8399:          ppij=0.;
                   8400:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8401:            if (mobilav>=1)
                   8402:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8403:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8404:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8405:            }
1.268     brouard  8406:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8407:          } /* end i */
                   8408:          fprintf(ficresf," %.3f", ppij);
                   8409:        }/* end j */
1.227     brouard  8410:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8411:       } /* end agec */
1.266     brouard  8412:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8413:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8414:     } /* end yearp */
                   8415:   } /* end  k */
1.219     brouard  8416:        
1.126     brouard  8417:   fclose(ficresf);
1.215     brouard  8418:   printf("End of Computing forecasting \n");
                   8419:   fprintf(ficlog,"End of Computing forecasting\n");
                   8420: 
1.126     brouard  8421: }
                   8422: 
1.269     brouard  8423: /************** Back Forecasting ******************/
                   8424:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8425:   /* back1, year, month, day of starting backection
                   8426:      agemin, agemax range of age
                   8427:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8428:      anback2 year of end of backprojection (same day and month as back1).
                   8429:      prevacurrent and prev are prevalences.
1.267     brouard  8430:   */
                   8431:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8432:   double agec; /* generic age */
1.268     brouard  8433:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8434:   double *popeffectif,*popcount;
                   8435:   double ***p3mat;
                   8436:   /* double ***mobaverage; */
                   8437:   char fileresfb[FILENAMELENGTH];
                   8438:  
1.268     brouard  8439:   agelim=AGEINF;
1.267     brouard  8440:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8441:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8442:      We still use firstpass and lastpass as another selection.
                   8443:   */
                   8444:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8445:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8446: 
                   8447:   /*Do we need to compute prevalence again?*/
                   8448: 
                   8449:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8450:   
                   8451:   strcpy(fileresfb,"FB_");
                   8452:   strcat(fileresfb,fileresu);
                   8453:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8454:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8455:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8456:   }
                   8457:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8458:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8459:   
                   8460:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8461:   
                   8462:    
                   8463:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8464:   if (stepm<=12) stepsize=1;
                   8465:   if(estepm < stepm){
                   8466:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8467:   }
1.270     brouard  8468:   else{
                   8469:     hstepm=estepm;   
                   8470:   }
                   8471:   if(estepm >= stepm){ /* Yes every two year */
                   8472:     stepsize=2;
                   8473:   }
1.267     brouard  8474:   
                   8475:   hstepm=hstepm/stepm;
                   8476:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8477:                                fractional in yp1 */
                   8478:   anprojmean=yp;
                   8479:   yp2=modf((yp1*12),&yp);
                   8480:   mprojmean=yp;
                   8481:   yp1=modf((yp2*30.5),&yp);
                   8482:   jprojmean=yp;
                   8483:   if(jprojmean==0) jprojmean=1;
                   8484:   if(mprojmean==0) jprojmean=1;
                   8485:   
                   8486:   i1=pow(2,cptcoveff);
                   8487:   if (cptcovn < 1){i1=1;}
                   8488:   
                   8489:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8490:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8491:   
                   8492:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8493:   
                   8494:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8495:   for(k=1; k<=i1;k++){
                   8496:     if(i1 != 1 && TKresult[nres]!= k)
                   8497:       continue;
                   8498:     if(invalidvarcomb[k]){
                   8499:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8500:       continue;
                   8501:     }
1.268     brouard  8502:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8503:     for(j=1;j<=cptcoveff;j++) {
                   8504:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8505:     }
                   8506:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8507:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8508:     }
                   8509:     fprintf(ficresfb," yearbproj age");
                   8510:     for(j=1; j<=nlstate+ndeath;j++){
                   8511:       for(i=1; i<=nlstate;i++)
1.268     brouard  8512:        fprintf(ficresfb," b%d%d",i,j);
                   8513:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8514:     }
                   8515:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8516:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8517:       fprintf(ficresfb,"\n");
                   8518:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.273     brouard  8519:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8520:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8521:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8522:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8523:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8524:        nhstepm = nhstepm/hstepm;
                   8525:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8526:        oldm=oldms;savm=savms;
1.268     brouard  8527:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8528:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8529:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8530:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8531:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8532:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8533:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8534:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8535:            break;
                   8536:          }
                   8537:        }
                   8538:        fprintf(ficresfb,"\n");
                   8539:        for(j=1;j<=cptcoveff;j++)
                   8540:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8541:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8542:        for(i=1; i<=nlstate+ndeath;i++) {
                   8543:          ppij=0.;ppi=0.;
                   8544:          for(j=1; j<=nlstate;j++) {
                   8545:            /* if (mobilav==1) */
1.269     brouard  8546:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8547:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8548:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8549:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8550:              /* else { */
                   8551:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8552:              /* } */
1.268     brouard  8553:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8554:          } /* end j */
                   8555:          if(ppi <0.99){
                   8556:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8557:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8558:          }
                   8559:          fprintf(ficresfb," %.3f", ppij);
                   8560:        }/* end j */
1.267     brouard  8561:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8562:       } /* end agec */
                   8563:     } /* end yearp */
                   8564:   } /* end k */
1.217     brouard  8565:   
1.267     brouard  8566:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8567:   
1.267     brouard  8568:   fclose(ficresfb);
                   8569:   printf("End of Computing Back forecasting \n");
                   8570:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8571:        
1.267     brouard  8572: }
1.217     brouard  8573: 
1.269     brouard  8574: /* Variance of prevalence limit: varprlim */
                   8575:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8576:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8577:  
                   8578:    char fileresvpl[FILENAMELENGTH];  
                   8579:    FILE *ficresvpl;
                   8580:    double **oldm, **savm;
                   8581:    double **varpl; /* Variances of prevalence limits by age */   
                   8582:    int i1, k, nres, j ;
                   8583:    
                   8584:     strcpy(fileresvpl,"VPL_");
                   8585:     strcat(fileresvpl,fileresu);
                   8586:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8587:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8588:       exit(0);
                   8589:     }
1.288     brouard  8590:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8591:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8592:     
                   8593:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8594:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8595:     
                   8596:     i1=pow(2,cptcoveff);
                   8597:     if (cptcovn < 1){i1=1;}
                   8598: 
                   8599:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8600:     for(k=1; k<=i1;k++){
                   8601:       if(i1 != 1 && TKresult[nres]!= k)
                   8602:        continue;
                   8603:       fprintf(ficresvpl,"\n#****** ");
                   8604:       printf("\n#****** ");
                   8605:       fprintf(ficlog,"\n#****** ");
                   8606:       for(j=1;j<=cptcoveff;j++) {
                   8607:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8608:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8609:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8610:       }
                   8611:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8612:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8613:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8614:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8615:       }        
                   8616:       fprintf(ficresvpl,"******\n");
                   8617:       printf("******\n");
                   8618:       fprintf(ficlog,"******\n");
                   8619:       
                   8620:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8621:       oldm=oldms;savm=savms;
                   8622:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8623:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8624:       /*}*/
                   8625:     }
                   8626:     
                   8627:     fclose(ficresvpl);
1.288     brouard  8628:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   8629:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  8630: 
                   8631:  }
                   8632: /* Variance of back prevalence: varbprlim */
                   8633:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8634:       /*------- Variance of back (stable) prevalence------*/
                   8635: 
                   8636:    char fileresvbl[FILENAMELENGTH];  
                   8637:    FILE  *ficresvbl;
                   8638: 
                   8639:    double **oldm, **savm;
                   8640:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8641:    int i1, k, nres, j ;
                   8642: 
                   8643:    strcpy(fileresvbl,"VBL_");
                   8644:    strcat(fileresvbl,fileresu);
                   8645:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8646:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8647:      exit(0);
                   8648:    }
                   8649:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8650:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8651:    
                   8652:    
                   8653:    i1=pow(2,cptcoveff);
                   8654:    if (cptcovn < 1){i1=1;}
                   8655:    
                   8656:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8657:      for(k=1; k<=i1;k++){
                   8658:        if(i1 != 1 && TKresult[nres]!= k)
                   8659:         continue;
                   8660:        fprintf(ficresvbl,"\n#****** ");
                   8661:        printf("\n#****** ");
                   8662:        fprintf(ficlog,"\n#****** ");
                   8663:        for(j=1;j<=cptcoveff;j++) {
                   8664:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8665:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8666:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8667:        }
                   8668:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8669:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8670:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8671:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8672:        }
                   8673:        fprintf(ficresvbl,"******\n");
                   8674:        printf("******\n");
                   8675:        fprintf(ficlog,"******\n");
                   8676:        
                   8677:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8678:        oldm=oldms;savm=savms;
                   8679:        
                   8680:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8681:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8682:        /*}*/
                   8683:      }
                   8684:    
                   8685:    fclose(ficresvbl);
                   8686:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8687:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8688: 
                   8689:  } /* End of varbprlim */
                   8690: 
1.126     brouard  8691: /************** Forecasting *****not tested NB*************/
1.227     brouard  8692: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8693:   
1.227     brouard  8694: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8695: /*   int *popage; */
                   8696: /*   double calagedatem, agelim, kk1, kk2; */
                   8697: /*   double *popeffectif,*popcount; */
                   8698: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8699: /*   /\* double ***mobaverage; *\/ */
                   8700: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8701: 
1.227     brouard  8702: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8703: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8704: /*   agelim=AGESUP; */
                   8705: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8706:   
1.227     brouard  8707: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8708:   
                   8709:   
1.227     brouard  8710: /*   strcpy(filerespop,"POP_");  */
                   8711: /*   strcat(filerespop,fileresu); */
                   8712: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8713: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8714: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8715: /*   } */
                   8716: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8717: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8718: 
1.227     brouard  8719: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8720: 
1.227     brouard  8721: /*   /\* if (mobilav!=0) { *\/ */
                   8722: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8723: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8724: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8725: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8726: /*   /\*   } *\/ */
                   8727: /*   /\* } *\/ */
1.126     brouard  8728: 
1.227     brouard  8729: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8730: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8731:   
1.227     brouard  8732: /*   agelim=AGESUP; */
1.126     brouard  8733:   
1.227     brouard  8734: /*   hstepm=1; */
                   8735: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8736:        
1.227     brouard  8737: /*   if (popforecast==1) { */
                   8738: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8739: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8740: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8741: /*     }  */
                   8742: /*     popage=ivector(0,AGESUP); */
                   8743: /*     popeffectif=vector(0,AGESUP); */
                   8744: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8745:     
1.227     brouard  8746: /*     i=1;    */
                   8747: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8748:     
1.227     brouard  8749: /*     imx=i; */
                   8750: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8751: /*   } */
1.218     brouard  8752:   
1.227     brouard  8753: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8754: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8755: /*       k=k+1; */
                   8756: /*       fprintf(ficrespop,"\n#******"); */
                   8757: /*       for(j=1;j<=cptcoveff;j++) { */
                   8758: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8759: /*       } */
                   8760: /*       fprintf(ficrespop,"******\n"); */
                   8761: /*       fprintf(ficrespop,"# Age"); */
                   8762: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8763: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8764:       
1.227     brouard  8765: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8766: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8767:        
1.227     brouard  8768: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8769: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8770: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8771:          
1.227     brouard  8772: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8773: /*       oldm=oldms;savm=savms; */
                   8774: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8775:          
1.227     brouard  8776: /*       for (h=0; h<=nhstepm; h++){ */
                   8777: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8778: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8779: /*         }  */
                   8780: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8781: /*           kk1=0.;kk2=0; */
                   8782: /*           for(i=1; i<=nlstate;i++) {               */
                   8783: /*             if (mobilav==1)  */
                   8784: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8785: /*             else { */
                   8786: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8787: /*             } */
                   8788: /*           } */
                   8789: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8790: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8791: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8792: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8793: /*           } */
                   8794: /*         } */
                   8795: /*         for(i=1; i<=nlstate;i++){ */
                   8796: /*           kk1=0.; */
                   8797: /*           for(j=1; j<=nlstate;j++){ */
                   8798: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8799: /*           } */
                   8800: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8801: /*         } */
1.218     brouard  8802:            
1.227     brouard  8803: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8804: /*           for(j=1; j<=nlstate;j++)  */
                   8805: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8806: /*       } */
                   8807: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8808: /*     } */
                   8809: /*       } */
1.218     brouard  8810:       
1.227     brouard  8811: /*       /\******\/ */
1.218     brouard  8812:       
1.227     brouard  8813: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8814: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8815: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8816: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8817: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8818:          
1.227     brouard  8819: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8820: /*       oldm=oldms;savm=savms; */
                   8821: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8822: /*       for (h=0; h<=nhstepm; h++){ */
                   8823: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8824: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8825: /*         }  */
                   8826: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8827: /*           kk1=0.;kk2=0; */
                   8828: /*           for(i=1; i<=nlstate;i++) {               */
                   8829: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8830: /*           } */
                   8831: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8832: /*         } */
                   8833: /*       } */
                   8834: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8835: /*     } */
                   8836: /*       } */
                   8837: /*     }  */
                   8838: /*   } */
1.218     brouard  8839:   
1.227     brouard  8840: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8841:   
1.227     brouard  8842: /*   if (popforecast==1) { */
                   8843: /*     free_ivector(popage,0,AGESUP); */
                   8844: /*     free_vector(popeffectif,0,AGESUP); */
                   8845: /*     free_vector(popcount,0,AGESUP); */
                   8846: /*   } */
                   8847: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8848: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8849: /*   fclose(ficrespop); */
                   8850: /* } /\* End of popforecast *\/ */
1.218     brouard  8851:  
1.126     brouard  8852: int fileappend(FILE *fichier, char *optionfich)
                   8853: {
                   8854:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8855:     printf("Problem with file: %s\n", optionfich);
                   8856:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8857:     return (0);
                   8858:   }
                   8859:   fflush(fichier);
                   8860:   return (1);
                   8861: }
                   8862: 
                   8863: 
                   8864: /**************** function prwizard **********************/
                   8865: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8866: {
                   8867: 
                   8868:   /* Wizard to print covariance matrix template */
                   8869: 
1.164     brouard  8870:   char ca[32], cb[32];
                   8871:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8872:   int numlinepar;
                   8873: 
                   8874:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8875:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8876:   for(i=1; i <=nlstate; i++){
                   8877:     jj=0;
                   8878:     for(j=1; j <=nlstate+ndeath; j++){
                   8879:       if(j==i) continue;
                   8880:       jj++;
                   8881:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8882:       printf("%1d%1d",i,j);
                   8883:       fprintf(ficparo,"%1d%1d",i,j);
                   8884:       for(k=1; k<=ncovmodel;k++){
                   8885:        /*        printf(" %lf",param[i][j][k]); */
                   8886:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8887:        printf(" 0.");
                   8888:        fprintf(ficparo," 0.");
                   8889:       }
                   8890:       printf("\n");
                   8891:       fprintf(ficparo,"\n");
                   8892:     }
                   8893:   }
                   8894:   printf("# Scales (for hessian or gradient estimation)\n");
                   8895:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8896:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8897:   for(i=1; i <=nlstate; i++){
                   8898:     jj=0;
                   8899:     for(j=1; j <=nlstate+ndeath; j++){
                   8900:       if(j==i) continue;
                   8901:       jj++;
                   8902:       fprintf(ficparo,"%1d%1d",i,j);
                   8903:       printf("%1d%1d",i,j);
                   8904:       fflush(stdout);
                   8905:       for(k=1; k<=ncovmodel;k++){
                   8906:        /*      printf(" %le",delti3[i][j][k]); */
                   8907:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8908:        printf(" 0.");
                   8909:        fprintf(ficparo," 0.");
                   8910:       }
                   8911:       numlinepar++;
                   8912:       printf("\n");
                   8913:       fprintf(ficparo,"\n");
                   8914:     }
                   8915:   }
                   8916:   printf("# Covariance matrix\n");
                   8917: /* # 121 Var(a12)\n\ */
                   8918: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8919: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8920: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8921: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8922: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8923: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8924: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8925:   fflush(stdout);
                   8926:   fprintf(ficparo,"# Covariance matrix\n");
                   8927:   /* # 121 Var(a12)\n\ */
                   8928:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8929:   /* #   ...\n\ */
                   8930:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8931:   
                   8932:   for(itimes=1;itimes<=2;itimes++){
                   8933:     jj=0;
                   8934:     for(i=1; i <=nlstate; i++){
                   8935:       for(j=1; j <=nlstate+ndeath; j++){
                   8936:        if(j==i) continue;
                   8937:        for(k=1; k<=ncovmodel;k++){
                   8938:          jj++;
                   8939:          ca[0]= k+'a'-1;ca[1]='\0';
                   8940:          if(itimes==1){
                   8941:            printf("#%1d%1d%d",i,j,k);
                   8942:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8943:          }else{
                   8944:            printf("%1d%1d%d",i,j,k);
                   8945:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8946:            /*  printf(" %.5le",matcov[i][j]); */
                   8947:          }
                   8948:          ll=0;
                   8949:          for(li=1;li <=nlstate; li++){
                   8950:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8951:              if(lj==li) continue;
                   8952:              for(lk=1;lk<=ncovmodel;lk++){
                   8953:                ll++;
                   8954:                if(ll<=jj){
                   8955:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8956:                  if(ll<jj){
                   8957:                    if(itimes==1){
                   8958:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8959:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8960:                    }else{
                   8961:                      printf(" 0.");
                   8962:                      fprintf(ficparo," 0.");
                   8963:                    }
                   8964:                  }else{
                   8965:                    if(itimes==1){
                   8966:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8967:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8968:                    }else{
                   8969:                      printf(" 0.");
                   8970:                      fprintf(ficparo," 0.");
                   8971:                    }
                   8972:                  }
                   8973:                }
                   8974:              } /* end lk */
                   8975:            } /* end lj */
                   8976:          } /* end li */
                   8977:          printf("\n");
                   8978:          fprintf(ficparo,"\n");
                   8979:          numlinepar++;
                   8980:        } /* end k*/
                   8981:       } /*end j */
                   8982:     } /* end i */
                   8983:   } /* end itimes */
                   8984: 
                   8985: } /* end of prwizard */
                   8986: /******************* Gompertz Likelihood ******************************/
                   8987: double gompertz(double x[])
                   8988: { 
                   8989:   double A,B,L=0.0,sump=0.,num=0.;
                   8990:   int i,n=0; /* n is the size of the sample */
                   8991: 
1.220     brouard  8992:   for (i=1;i<=imx ; i++) {
1.126     brouard  8993:     sump=sump+weight[i];
                   8994:     /*    sump=sump+1;*/
                   8995:     num=num+1;
                   8996:   }
                   8997:  
                   8998:  
                   8999:   /* for (i=0; i<=imx; i++) 
                   9000:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9001: 
                   9002:   for (i=1;i<=imx ; i++)
                   9003:     {
                   9004:       if (cens[i] == 1 && wav[i]>1)
                   9005:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9006:       
                   9007:       if (cens[i] == 0 && wav[i]>1)
                   9008:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   9009:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   9010:       
                   9011:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9012:       if (wav[i] > 1 ) { /* ??? */
                   9013:        L=L+A*weight[i];
                   9014:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9015:       }
                   9016:     }
                   9017: 
                   9018:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9019:  
                   9020:   return -2*L*num/sump;
                   9021: }
                   9022: 
1.136     brouard  9023: #ifdef GSL
                   9024: /******************* Gompertz_f Likelihood ******************************/
                   9025: double gompertz_f(const gsl_vector *v, void *params)
                   9026: { 
                   9027:   double A,B,LL=0.0,sump=0.,num=0.;
                   9028:   double *x= (double *) v->data;
                   9029:   int i,n=0; /* n is the size of the sample */
                   9030: 
                   9031:   for (i=0;i<=imx-1 ; i++) {
                   9032:     sump=sump+weight[i];
                   9033:     /*    sump=sump+1;*/
                   9034:     num=num+1;
                   9035:   }
                   9036:  
                   9037:  
                   9038:   /* for (i=0; i<=imx; i++) 
                   9039:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9040:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9041:   for (i=1;i<=imx ; i++)
                   9042:     {
                   9043:       if (cens[i] == 1 && wav[i]>1)
                   9044:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9045:       
                   9046:       if (cens[i] == 0 && wav[i]>1)
                   9047:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9048:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9049:       
                   9050:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9051:       if (wav[i] > 1 ) { /* ??? */
                   9052:        LL=LL+A*weight[i];
                   9053:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9054:       }
                   9055:     }
                   9056: 
                   9057:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9058:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9059:  
                   9060:   return -2*LL*num/sump;
                   9061: }
                   9062: #endif
                   9063: 
1.126     brouard  9064: /******************* Printing html file ***********/
1.201     brouard  9065: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9066:                  int lastpass, int stepm, int weightopt, char model[],\
                   9067:                  int imx,  double p[],double **matcov,double agemortsup){
                   9068:   int i,k;
                   9069: 
                   9070:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9071:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9072:   for (i=1;i<=2;i++) 
                   9073:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9074:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9075:   fprintf(fichtm,"</ul>");
                   9076: 
                   9077: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9078: 
                   9079:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9080: 
                   9081:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9082:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9083: 
                   9084:  
                   9085:   fflush(fichtm);
                   9086: }
                   9087: 
                   9088: /******************* Gnuplot file **************/
1.201     brouard  9089: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9090: 
                   9091:   char dirfileres[132],optfileres[132];
1.164     brouard  9092: 
1.126     brouard  9093:   int ng;
                   9094: 
                   9095: 
                   9096:   /*#ifdef windows */
                   9097:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9098:     /*#endif */
                   9099: 
                   9100: 
                   9101:   strcpy(dirfileres,optionfilefiname);
                   9102:   strcpy(optfileres,"vpl");
1.199     brouard  9103:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9104:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9105:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9106:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9107:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9108: 
                   9109: } 
                   9110: 
1.136     brouard  9111: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9112: {
1.126     brouard  9113: 
1.136     brouard  9114:   /*-------- data file ----------*/
                   9115:   FILE *fic;
                   9116:   char dummy[]="                         ";
1.240     brouard  9117:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9118:   int lstra;
1.136     brouard  9119:   int linei, month, year,iout;
                   9120:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9121:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9122:   char *stratrunc;
1.223     brouard  9123: 
1.240     brouard  9124:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9125:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9126: 
1.240     brouard  9127:   for(v=1; v <=ncovcol;v++){
                   9128:     DummyV[v]=0;
                   9129:     FixedV[v]=0;
                   9130:   }
                   9131:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9132:     DummyV[v]=1;
                   9133:     FixedV[v]=0;
                   9134:   }
                   9135:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9136:     DummyV[v]=0;
                   9137:     FixedV[v]=1;
                   9138:   }
                   9139:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9140:     DummyV[v]=1;
                   9141:     FixedV[v]=1;
                   9142:   }
                   9143:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9144:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9145:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9146:   }
1.126     brouard  9147: 
1.136     brouard  9148:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9149:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9150:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9151:   }
1.126     brouard  9152: 
1.136     brouard  9153:   i=1;
                   9154:   linei=0;
                   9155:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9156:     linei=linei+1;
                   9157:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9158:       if(line[j] == '\t')
                   9159:        line[j] = ' ';
                   9160:     }
                   9161:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9162:       ;
                   9163:     };
                   9164:     line[j+1]=0;  /* Trims blanks at end of line */
                   9165:     if(line[0]=='#'){
                   9166:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9167:       printf("Comment line\n%s\n",line);
                   9168:       continue;
                   9169:     }
                   9170:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9171:     strcpy(line, linetmp);
1.223     brouard  9172:     
                   9173:     /* Loops on waves */
                   9174:     for (j=maxwav;j>=1;j--){
                   9175:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9176:        cutv(stra, strb, line, ' '); 
                   9177:        if(strb[0]=='.') { /* Missing value */
                   9178:          lval=-1;
                   9179:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9180:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9181:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9182:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9183:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9184:            return 1;
                   9185:          }
                   9186:        }else{
                   9187:          errno=0;
                   9188:          /* what_kind_of_number(strb); */
                   9189:          dval=strtod(strb,&endptr); 
                   9190:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9191:          /* if(strb != endptr && *endptr == '\0') */
                   9192:          /*    dval=dlval; */
                   9193:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9194:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9195:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9196:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9197:            return 1;
                   9198:          }
                   9199:          cotqvar[j][iv][i]=dval; 
                   9200:          cotvar[j][ntv+iv][i]=dval; 
                   9201:        }
                   9202:        strcpy(line,stra);
1.223     brouard  9203:       }/* end loop ntqv */
1.225     brouard  9204:       
1.223     brouard  9205:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9206:        cutv(stra, strb, line, ' '); 
                   9207:        if(strb[0]=='.') { /* Missing value */
                   9208:          lval=-1;
                   9209:        }else{
                   9210:          errno=0;
                   9211:          lval=strtol(strb,&endptr,10); 
                   9212:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9213:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9214:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9215:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9216:            return 1;
                   9217:          }
                   9218:        }
                   9219:        if(lval <-1 || lval >1){
                   9220:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9221:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9222:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9223:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9224:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9225:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9226:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9227:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9228:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9229:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9230:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9231:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9232:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9233:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9234:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9235:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9236:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9237:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9238:          return 1;
                   9239:        }
                   9240:        cotvar[j][iv][i]=(double)(lval);
                   9241:        strcpy(line,stra);
1.223     brouard  9242:       }/* end loop ntv */
1.225     brouard  9243:       
1.223     brouard  9244:       /* Statuses  at wave */
1.137     brouard  9245:       cutv(stra, strb, line, ' '); 
1.223     brouard  9246:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9247:        lval=-1;
1.136     brouard  9248:       }else{
1.238     brouard  9249:        errno=0;
                   9250:        lval=strtol(strb,&endptr,10); 
                   9251:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9252:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9253:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9254:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9255:          return 1;
                   9256:        }
1.136     brouard  9257:       }
1.225     brouard  9258:       
1.136     brouard  9259:       s[j][i]=lval;
1.225     brouard  9260:       
1.223     brouard  9261:       /* Date of Interview */
1.136     brouard  9262:       strcpy(line,stra);
                   9263:       cutv(stra, strb,line,' ');
1.169     brouard  9264:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9265:       }
1.169     brouard  9266:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9267:        month=99;
                   9268:        year=9999;
1.136     brouard  9269:       }else{
1.225     brouard  9270:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9271:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9272:        return 1;
1.136     brouard  9273:       }
                   9274:       anint[j][i]= (double) year; 
                   9275:       mint[j][i]= (double)month; 
                   9276:       strcpy(line,stra);
1.223     brouard  9277:     } /* End loop on waves */
1.225     brouard  9278:     
1.223     brouard  9279:     /* Date of death */
1.136     brouard  9280:     cutv(stra, strb,line,' '); 
1.169     brouard  9281:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9282:     }
1.169     brouard  9283:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9284:       month=99;
                   9285:       year=9999;
                   9286:     }else{
1.141     brouard  9287:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9288:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9289:       return 1;
1.136     brouard  9290:     }
                   9291:     andc[i]=(double) year; 
                   9292:     moisdc[i]=(double) month; 
                   9293:     strcpy(line,stra);
                   9294:     
1.223     brouard  9295:     /* Date of birth */
1.136     brouard  9296:     cutv(stra, strb,line,' '); 
1.169     brouard  9297:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9298:     }
1.169     brouard  9299:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9300:       month=99;
                   9301:       year=9999;
                   9302:     }else{
1.141     brouard  9303:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9304:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9305:       return 1;
1.136     brouard  9306:     }
                   9307:     if (year==9999) {
1.141     brouard  9308:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9309:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9310:       return 1;
                   9311:       
1.136     brouard  9312:     }
                   9313:     annais[i]=(double)(year);
                   9314:     moisnais[i]=(double)(month); 
                   9315:     strcpy(line,stra);
1.225     brouard  9316:     
1.223     brouard  9317:     /* Sample weight */
1.136     brouard  9318:     cutv(stra, strb,line,' '); 
                   9319:     errno=0;
                   9320:     dval=strtod(strb,&endptr); 
                   9321:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9322:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9323:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9324:       fflush(ficlog);
                   9325:       return 1;
                   9326:     }
                   9327:     weight[i]=dval; 
                   9328:     strcpy(line,stra);
1.225     brouard  9329:     
1.223     brouard  9330:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9331:       cutv(stra, strb, line, ' '); 
                   9332:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9333:        lval=-1;
1.223     brouard  9334:       }else{
1.225     brouard  9335:        errno=0;
                   9336:        /* what_kind_of_number(strb); */
                   9337:        dval=strtod(strb,&endptr);
                   9338:        /* if(strb != endptr && *endptr == '\0') */
                   9339:        /*   dval=dlval; */
                   9340:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9341:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9342:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9343:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9344:          return 1;
                   9345:        }
                   9346:        coqvar[iv][i]=dval; 
1.226     brouard  9347:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9348:       }
                   9349:       strcpy(line,stra);
                   9350:     }/* end loop nqv */
1.136     brouard  9351:     
1.223     brouard  9352:     /* Covariate values */
1.136     brouard  9353:     for (j=ncovcol;j>=1;j--){
                   9354:       cutv(stra, strb,line,' '); 
1.223     brouard  9355:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9356:        lval=-1;
1.136     brouard  9357:       }else{
1.225     brouard  9358:        errno=0;
                   9359:        lval=strtol(strb,&endptr,10); 
                   9360:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9361:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9362:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9363:          return 1;
                   9364:        }
1.136     brouard  9365:       }
                   9366:       if(lval <-1 || lval >1){
1.225     brouard  9367:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9368:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9369:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9370:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9371:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9372:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9373:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9374:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9375:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9376:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9377:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9378:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9379:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9380:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9381:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9382:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9383:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9384:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9385:        return 1;
1.136     brouard  9386:       }
                   9387:       covar[j][i]=(double)(lval);
                   9388:       strcpy(line,stra);
                   9389:     }  
                   9390:     lstra=strlen(stra);
1.225     brouard  9391:     
1.136     brouard  9392:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9393:       stratrunc = &(stra[lstra-9]);
                   9394:       num[i]=atol(stratrunc);
                   9395:     }
                   9396:     else
                   9397:       num[i]=atol(stra);
                   9398:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9399:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9400:     
                   9401:     i=i+1;
                   9402:   } /* End loop reading  data */
1.225     brouard  9403:   
1.136     brouard  9404:   *imax=i-1; /* Number of individuals */
                   9405:   fclose(fic);
1.225     brouard  9406:   
1.136     brouard  9407:   return (0);
1.164     brouard  9408:   /* endread: */
1.225     brouard  9409:   printf("Exiting readdata: ");
                   9410:   fclose(fic);
                   9411:   return (1);
1.223     brouard  9412: }
1.126     brouard  9413: 
1.234     brouard  9414: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9415:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9416:   while (*p2 == ' ')
1.234     brouard  9417:     p2++; 
                   9418:   /* while ((*p1++ = *p2++) !=0) */
                   9419:   /*   ; */
                   9420:   /* do */
                   9421:   /*   while (*p2 == ' ') */
                   9422:   /*     p2++; */
                   9423:   /* while (*p1++ == *p2++); */
                   9424:   *stri=p2; 
1.145     brouard  9425: }
                   9426: 
1.235     brouard  9427: int decoderesult ( char resultline[], int nres)
1.230     brouard  9428: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9429: {
1.235     brouard  9430:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9431:   char resultsav[MAXLINE];
1.234     brouard  9432:   int resultmodel[MAXLINE];
                   9433:   int modelresult[MAXLINE];
1.230     brouard  9434:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9435: 
1.234     brouard  9436:   removefirstspace(&resultline);
1.233     brouard  9437:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9438: 
                   9439:   if (strstr(resultline,"v") !=0){
                   9440:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9441:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9442:     return 1;
                   9443:   }
                   9444:   trimbb(resultsav, resultline);
                   9445:   if (strlen(resultsav) >1){
                   9446:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9447:   }
1.253     brouard  9448:   if(j == 0){ /* Resultline but no = */
                   9449:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9450:     return (0);
                   9451:   }
                   9452:     
1.234     brouard  9453:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9454:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9455:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9456:   }
                   9457:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9458:     if(nbocc(resultsav,'=') >1){
                   9459:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9460:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9461:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9462:     }else
                   9463:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9464:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9465:     
1.230     brouard  9466:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9467:     Tvarsel[k]=atoi(strc);
                   9468:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9469:     /* cptcovsel++;     */
                   9470:     if (nbocc(stra,'=') >0)
                   9471:       strcpy(resultsav,stra); /* and analyzes it */
                   9472:   }
1.235     brouard  9473:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9474:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9475:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9476:       match=0;
1.236     brouard  9477:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9478:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9479:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9480:          match=1;
                   9481:          break;
                   9482:        }
                   9483:       }
                   9484:       if(match == 0){
                   9485:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9486:       }
                   9487:     }
                   9488:   }
1.235     brouard  9489:   /* Checking for missing or useless values in comparison of current model needs */
                   9490:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9491:     match=0;
1.235     brouard  9492:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9493:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9494:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9495:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9496:          ++match;
                   9497:        }
                   9498:       }
                   9499:     }
                   9500:     if(match == 0){
                   9501:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9502:     }else if(match > 1){
                   9503:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9504:     }
                   9505:   }
1.235     brouard  9506:       
1.234     brouard  9507:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9508:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9509:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9510:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9511:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9512:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9513:   /*    1 0 0 0 */
                   9514:   /*    2 1 0 0 */
                   9515:   /*    3 0 1 0 */ 
                   9516:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9517:   /*    5 0 0 1 */
                   9518:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9519:   /*    7 0 1 1 */
                   9520:   /*    8 1 1 1 */
1.237     brouard  9521:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9522:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9523:   /* V5*age V5 known which value for nres?  */
                   9524:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9525:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9526:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9527:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9528:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9529:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9530:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9531:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9532:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9533:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9534:       k4++;;
                   9535:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9536:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9537:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9538:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9539:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9540:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9541:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9542:       k4q++;;
                   9543:     }
                   9544:   }
1.234     brouard  9545:   
1.235     brouard  9546:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9547:   return (0);
                   9548: }
1.235     brouard  9549: 
1.230     brouard  9550: int decodemodel( char model[], int lastobs)
                   9551:  /**< This routine decodes the model and returns:
1.224     brouard  9552:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9553:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9554:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9555:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9556:        * - cptcovage number of covariates with age*products =2
                   9557:        * - cptcovs number of simple covariates
                   9558:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9559:        *     which is a new column after the 9 (ncovcol) variables. 
                   9560:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9561:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9562:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9563:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9564:        */
1.136     brouard  9565: {
1.238     brouard  9566:   int i, j, k, ks, v;
1.227     brouard  9567:   int  j1, k1, k2, k3, k4;
1.136     brouard  9568:   char modelsav[80];
1.145     brouard  9569:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9570:   char *strpt;
1.136     brouard  9571: 
1.145     brouard  9572:   /*removespace(model);*/
1.136     brouard  9573:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9574:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9575:     if (strstr(model,"AGE") !=0){
1.192     brouard  9576:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9577:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9578:       return 1;
                   9579:     }
1.141     brouard  9580:     if (strstr(model,"v") !=0){
                   9581:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9582:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9583:       return 1;
                   9584:     }
1.187     brouard  9585:     strcpy(modelsav,model); 
                   9586:     if ((strpt=strstr(model,"age*age")) !=0){
                   9587:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9588:       if(strpt != model){
1.234     brouard  9589:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9590:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9591:  corresponding column of parameters.\n",model);
1.234     brouard  9592:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9593:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9594:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9595:        return 1;
1.225     brouard  9596:       }
1.187     brouard  9597:       nagesqr=1;
                   9598:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9599:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9600:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9601:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9602:       else 
1.234     brouard  9603:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9604:     }else
                   9605:       nagesqr=0;
                   9606:     if (strlen(modelsav) >1){
                   9607:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9608:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9609:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9610:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9611:                     * cst, age and age*age 
                   9612:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9613:       /* including age products which are counted in cptcovage.
                   9614:        * but the covariates which are products must be treated 
                   9615:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9616:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9617:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9618:       
                   9619:       
1.187     brouard  9620:       /*   Design
                   9621:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9622:        *  <          ncovcol=8                >
                   9623:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9624:        *   k=  1    2      3       4     5       6      7        8
                   9625:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9626:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9627:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9628:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9629:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9630:        *  Tage[++cptcovage]=k
                   9631:        *       if products, new covar are created after ncovcol with k1
                   9632:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9633:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9634:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9635:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9636:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9637:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9638:        *  <          ncovcol=8                >
                   9639:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9640:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9641:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9642:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9643:        * p Tprod[1]@2={                         6, 5}
                   9644:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9645:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9646:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9647:        *How to reorganize?
                   9648:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9649:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9650:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9651:        * Struct []
                   9652:        */
1.225     brouard  9653:       
1.187     brouard  9654:       /* This loop fills the array Tvar from the string 'model'.*/
                   9655:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9656:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9657:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9658:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9659:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9660:       /*       k=1 Tvar[1]=2 (from V2) */
                   9661:       /*       k=5 Tvar[5] */
                   9662:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9663:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9664:       /*       } */
1.198     brouard  9665:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9666:       /*
                   9667:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9668:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9669:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9670:       }
1.187     brouard  9671:       cptcovage=0;
                   9672:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9673:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9674:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9675:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9676:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9677:        /*scanf("%d",i);*/
                   9678:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9679:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9680:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9681:            /* covar is not filled and then is empty */
                   9682:            cptcovprod--;
                   9683:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9684:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9685:            Typevar[k]=1;  /* 1 for age product */
                   9686:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9687:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9688:            /*printf("stre=%s ", stre);*/
                   9689:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9690:            cptcovprod--;
                   9691:            cutl(stre,strb,strc,'V');
                   9692:            Tvar[k]=atoi(stre);
                   9693:            Typevar[k]=1;  /* 1 for age product */
                   9694:            cptcovage++;
                   9695:            Tage[cptcovage]=k;
                   9696:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9697:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9698:            cptcovn++;
                   9699:            cptcovprodnoage++;k1++;
                   9700:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9701:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9702:                                                because this model-covariate is a construction we invent a new column
                   9703:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9704:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9705:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9706:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9707:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9708:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9709:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9710:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9711:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9712:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9713:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9714:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9715:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9716:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9717:            for (i=1; i<=lastobs;i++){
                   9718:              /* Computes the new covariate which is a product of
                   9719:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9720:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9721:            }
                   9722:          } /* End age is not in the model */
                   9723:        } /* End if model includes a product */
                   9724:        else { /* no more sum */
                   9725:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9726:          /*  scanf("%d",i);*/
                   9727:          cutl(strd,strc,strb,'V');
                   9728:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9729:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9730:          Tvar[k]=atoi(strd);
                   9731:          Typevar[k]=0;  /* 0 for simple covariates */
                   9732:        }
                   9733:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9734:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9735:                                  scanf("%d",i);*/
1.187     brouard  9736:       } /* end of loop + on total covariates */
                   9737:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9738:   } /* end if strlen(model == 0) */
1.136     brouard  9739:   
                   9740:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9741:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9742:   
1.136     brouard  9743:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9744:      printf("cptcovprod=%d ", cptcovprod);
                   9745:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9746:      scanf("%d ",i);*/
                   9747: 
                   9748: 
1.230     brouard  9749: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9750:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9751: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9752:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9753:    k =           1    2   3     4       5       6      7      8        9
                   9754:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9755:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9756:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9757:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9758:          Tmodelind[combination of covar]=k;
1.225     brouard  9759: */  
                   9760: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9761:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9762:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9763:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9764:   printf("Model=%s\n\
                   9765: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9766: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9767: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9768:   fprintf(ficlog,"Model=%s\n\
                   9769: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9770: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9771: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  9772:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9773:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9774:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9775:       Fixed[k]= 0;
                   9776:       Dummy[k]= 0;
1.225     brouard  9777:       ncoveff++;
1.232     brouard  9778:       ncovf++;
1.234     brouard  9779:       nsd++;
                   9780:       modell[k].maintype= FTYPE;
                   9781:       TvarsD[nsd]=Tvar[k];
                   9782:       TvarsDind[nsd]=k;
                   9783:       TvarF[ncovf]=Tvar[k];
                   9784:       TvarFind[ncovf]=k;
                   9785:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9786:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9787:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9788:       Fixed[k]= 0;
                   9789:       Dummy[k]= 0;
                   9790:       ncoveff++;
                   9791:       ncovf++;
                   9792:       modell[k].maintype= FTYPE;
                   9793:       TvarF[ncovf]=Tvar[k];
                   9794:       TvarFind[ncovf]=k;
1.230     brouard  9795:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9796:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9797:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9798:       Fixed[k]= 0;
                   9799:       Dummy[k]= 1;
1.230     brouard  9800:       nqfveff++;
1.234     brouard  9801:       modell[k].maintype= FTYPE;
                   9802:       modell[k].subtype= FQ;
                   9803:       nsq++;
                   9804:       TvarsQ[nsq]=Tvar[k];
                   9805:       TvarsQind[nsq]=k;
1.232     brouard  9806:       ncovf++;
1.234     brouard  9807:       TvarF[ncovf]=Tvar[k];
                   9808:       TvarFind[ncovf]=k;
1.231     brouard  9809:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9810:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9811:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9812:       Fixed[k]= 1;
                   9813:       Dummy[k]= 0;
1.225     brouard  9814:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9815:       modell[k].maintype= VTYPE;
                   9816:       modell[k].subtype= VD;
                   9817:       nsd++;
                   9818:       TvarsD[nsd]=Tvar[k];
                   9819:       TvarsDind[nsd]=k;
                   9820:       ncovv++; /* Only simple time varying variables */
                   9821:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9822:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9823:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9824:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9825:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9826:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9827:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9828:       Fixed[k]= 1;
                   9829:       Dummy[k]= 1;
                   9830:       nqtveff++;
                   9831:       modell[k].maintype= VTYPE;
                   9832:       modell[k].subtype= VQ;
                   9833:       ncovv++; /* Only simple time varying variables */
                   9834:       nsq++;
                   9835:       TvarsQ[nsq]=Tvar[k];
                   9836:       TvarsQind[nsq]=k;
                   9837:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9838:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9839:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9840:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9841:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9842:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9843:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9844:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9845:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9846:       ncova++;
                   9847:       TvarA[ncova]=Tvar[k];
                   9848:       TvarAind[ncova]=k;
1.231     brouard  9849:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9850:        Fixed[k]= 2;
                   9851:        Dummy[k]= 2;
                   9852:        modell[k].maintype= ATYPE;
                   9853:        modell[k].subtype= APFD;
                   9854:        /* ncoveff++; */
1.227     brouard  9855:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9856:        Fixed[k]= 2;
                   9857:        Dummy[k]= 3;
                   9858:        modell[k].maintype= ATYPE;
                   9859:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9860:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9861:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9862:        Fixed[k]= 3;
                   9863:        Dummy[k]= 2;
                   9864:        modell[k].maintype= ATYPE;
                   9865:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9866:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9867:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9868:        Fixed[k]= 3;
                   9869:        Dummy[k]= 3;
                   9870:        modell[k].maintype= ATYPE;
                   9871:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9872:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9873:       }
                   9874:     }else if (Typevar[k] == 2) {  /* product without age */
                   9875:       k1=Tposprod[k];
                   9876:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9877:        if(Tvard[k1][2] <=ncovcol){
                   9878:          Fixed[k]= 1;
                   9879:          Dummy[k]= 0;
                   9880:          modell[k].maintype= FTYPE;
                   9881:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9882:          ncovf++; /* Fixed variables without age */
                   9883:          TvarF[ncovf]=Tvar[k];
                   9884:          TvarFind[ncovf]=k;
                   9885:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9886:          Fixed[k]= 0;  /* or 2 ?*/
                   9887:          Dummy[k]= 1;
                   9888:          modell[k].maintype= FTYPE;
                   9889:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9890:          ncovf++; /* Varying variables without age */
                   9891:          TvarF[ncovf]=Tvar[k];
                   9892:          TvarFind[ncovf]=k;
                   9893:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9894:          Fixed[k]= 1;
                   9895:          Dummy[k]= 0;
                   9896:          modell[k].maintype= VTYPE;
                   9897:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9898:          ncovv++; /* Varying variables without age */
                   9899:          TvarV[ncovv]=Tvar[k];
                   9900:          TvarVind[ncovv]=k;
                   9901:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9902:          Fixed[k]= 1;
                   9903:          Dummy[k]= 1;
                   9904:          modell[k].maintype= VTYPE;
                   9905:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9906:          ncovv++; /* Varying variables without age */
                   9907:          TvarV[ncovv]=Tvar[k];
                   9908:          TvarVind[ncovv]=k;
                   9909:        }
1.227     brouard  9910:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9911:        if(Tvard[k1][2] <=ncovcol){
                   9912:          Fixed[k]= 0;  /* or 2 ?*/
                   9913:          Dummy[k]= 1;
                   9914:          modell[k].maintype= FTYPE;
                   9915:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9916:          ncovf++; /* Fixed variables without age */
                   9917:          TvarF[ncovf]=Tvar[k];
                   9918:          TvarFind[ncovf]=k;
                   9919:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9920:          Fixed[k]= 1;
                   9921:          Dummy[k]= 1;
                   9922:          modell[k].maintype= VTYPE;
                   9923:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9924:          ncovv++; /* Varying variables without age */
                   9925:          TvarV[ncovv]=Tvar[k];
                   9926:          TvarVind[ncovv]=k;
                   9927:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9928:          Fixed[k]= 1;
                   9929:          Dummy[k]= 1;
                   9930:          modell[k].maintype= VTYPE;
                   9931:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9932:          ncovv++; /* Varying variables without age */
                   9933:          TvarV[ncovv]=Tvar[k];
                   9934:          TvarVind[ncovv]=k;
                   9935:          ncovv++; /* Varying variables without age */
                   9936:          TvarV[ncovv]=Tvar[k];
                   9937:          TvarVind[ncovv]=k;
                   9938:        }
1.227     brouard  9939:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9940:        if(Tvard[k1][2] <=ncovcol){
                   9941:          Fixed[k]= 1;
                   9942:          Dummy[k]= 1;
                   9943:          modell[k].maintype= VTYPE;
                   9944:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9945:          ncovv++; /* Varying variables without age */
                   9946:          TvarV[ncovv]=Tvar[k];
                   9947:          TvarVind[ncovv]=k;
                   9948:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9949:          Fixed[k]= 1;
                   9950:          Dummy[k]= 1;
                   9951:          modell[k].maintype= VTYPE;
                   9952:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9953:          ncovv++; /* Varying variables without age */
                   9954:          TvarV[ncovv]=Tvar[k];
                   9955:          TvarVind[ncovv]=k;
                   9956:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9957:          Fixed[k]= 1;
                   9958:          Dummy[k]= 0;
                   9959:          modell[k].maintype= VTYPE;
                   9960:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9961:          ncovv++; /* Varying variables without age */
                   9962:          TvarV[ncovv]=Tvar[k];
                   9963:          TvarVind[ncovv]=k;
                   9964:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9965:          Fixed[k]= 1;
                   9966:          Dummy[k]= 1;
                   9967:          modell[k].maintype= VTYPE;
                   9968:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9969:          ncovv++; /* Varying variables without age */
                   9970:          TvarV[ncovv]=Tvar[k];
                   9971:          TvarVind[ncovv]=k;
                   9972:        }
1.227     brouard  9973:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9974:        if(Tvard[k1][2] <=ncovcol){
                   9975:          Fixed[k]= 1;
                   9976:          Dummy[k]= 1;
                   9977:          modell[k].maintype= VTYPE;
                   9978:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9979:          ncovv++; /* Varying variables without age */
                   9980:          TvarV[ncovv]=Tvar[k];
                   9981:          TvarVind[ncovv]=k;
                   9982:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9983:          Fixed[k]= 1;
                   9984:          Dummy[k]= 1;
                   9985:          modell[k].maintype= VTYPE;
                   9986:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9987:          ncovv++; /* Varying variables without age */
                   9988:          TvarV[ncovv]=Tvar[k];
                   9989:          TvarVind[ncovv]=k;
                   9990:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9991:          Fixed[k]= 1;
                   9992:          Dummy[k]= 1;
                   9993:          modell[k].maintype= VTYPE;
                   9994:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9995:          ncovv++; /* Varying variables without age */
                   9996:          TvarV[ncovv]=Tvar[k];
                   9997:          TvarVind[ncovv]=k;
                   9998:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9999:          Fixed[k]= 1;
                   10000:          Dummy[k]= 1;
                   10001:          modell[k].maintype= VTYPE;
                   10002:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10003:          ncovv++; /* Varying variables without age */
                   10004:          TvarV[ncovv]=Tvar[k];
                   10005:          TvarVind[ncovv]=k;
                   10006:        }
1.227     brouard  10007:       }else{
1.240     brouard  10008:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10009:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10010:       } /*end k1*/
1.225     brouard  10011:     }else{
1.226     brouard  10012:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10013:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10014:     }
1.227     brouard  10015:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10016:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10017:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10018:   }
                   10019:   /* Searching for doublons in the model */
                   10020:   for(k1=1; k1<= cptcovt;k1++){
                   10021:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10022:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10023:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10024:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10025:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10026:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10027:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10028:            return(1);
                   10029:          }
                   10030:        }else if (Typevar[k1] ==2){
                   10031:          k3=Tposprod[k1];
                   10032:          k4=Tposprod[k2];
                   10033:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10034:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10035:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10036:            return(1);
                   10037:          }
                   10038:        }
1.227     brouard  10039:       }
                   10040:     }
1.225     brouard  10041:   }
                   10042:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10043:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10044:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10045:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10046:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10047:   /*endread:*/
1.225     brouard  10048:   printf("Exiting decodemodel: ");
                   10049:   return (1);
1.136     brouard  10050: }
                   10051: 
1.169     brouard  10052: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10053: {/* Check ages at death */
1.136     brouard  10054:   int i, m;
1.218     brouard  10055:   int firstone=0;
                   10056:   
1.136     brouard  10057:   for (i=1; i<=imx; i++) {
                   10058:     for(m=2; (m<= maxwav); m++) {
                   10059:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10060:        anint[m][i]=9999;
1.216     brouard  10061:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10062:          s[m][i]=-1;
1.136     brouard  10063:       }
                   10064:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10065:        *nberr = *nberr + 1;
1.218     brouard  10066:        if(firstone == 0){
                   10067:          firstone=1;
1.260     brouard  10068:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10069:        }
1.262     brouard  10070:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10071:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10072:       }
                   10073:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10074:        (*nberr)++;
1.259     brouard  10075:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10076:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10077:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10078:       }
                   10079:     }
                   10080:   }
                   10081: 
                   10082:   for (i=1; i<=imx; i++)  {
                   10083:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10084:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10085:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10086:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10087:          if(agedc[i]>0){
                   10088:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10089:              agev[m][i]=agedc[i];
1.214     brouard  10090:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10091:            }else {
1.136     brouard  10092:              if ((int)andc[i]!=9999){
                   10093:                nbwarn++;
                   10094:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10095:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10096:                agev[m][i]=-1;
                   10097:              }
                   10098:            }
1.169     brouard  10099:          } /* agedc > 0 */
1.214     brouard  10100:        } /* end if */
1.136     brouard  10101:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10102:                                 years but with the precision of a month */
                   10103:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10104:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10105:            agev[m][i]=1;
                   10106:          else if(agev[m][i] < *agemin){ 
                   10107:            *agemin=agev[m][i];
                   10108:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10109:          }
                   10110:          else if(agev[m][i] >*agemax){
                   10111:            *agemax=agev[m][i];
1.156     brouard  10112:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10113:          }
                   10114:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10115:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10116:        } /* en if 9*/
1.136     brouard  10117:        else { /* =9 */
1.214     brouard  10118:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10119:          agev[m][i]=1;
                   10120:          s[m][i]=-1;
                   10121:        }
                   10122:       }
1.214     brouard  10123:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10124:        agev[m][i]=1;
1.214     brouard  10125:       else{
                   10126:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10127:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10128:        agev[m][i]=0;
                   10129:       }
                   10130:     } /* End for lastpass */
                   10131:   }
1.136     brouard  10132:     
                   10133:   for (i=1; i<=imx; i++)  {
                   10134:     for(m=firstpass; (m<=lastpass); m++){
                   10135:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10136:        (*nberr)++;
1.136     brouard  10137:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10138:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10139:        return 1;
                   10140:       }
                   10141:     }
                   10142:   }
                   10143: 
                   10144:   /*for (i=1; i<=imx; i++){
                   10145:   for (m=firstpass; (m<lastpass); m++){
                   10146:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10147: }
                   10148: 
                   10149: }*/
                   10150: 
                   10151: 
1.139     brouard  10152:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10153:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10154: 
                   10155:   return (0);
1.164     brouard  10156:  /* endread:*/
1.136     brouard  10157:     printf("Exiting calandcheckages: ");
                   10158:     return (1);
                   10159: }
                   10160: 
1.172     brouard  10161: #if defined(_MSC_VER)
                   10162: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10163: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10164: //#include "stdafx.h"
                   10165: //#include <stdio.h>
                   10166: //#include <tchar.h>
                   10167: //#include <windows.h>
                   10168: //#include <iostream>
                   10169: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10170: 
                   10171: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10172: 
                   10173: BOOL IsWow64()
                   10174: {
                   10175:        BOOL bIsWow64 = FALSE;
                   10176: 
                   10177:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10178:        //  (HANDLE, PBOOL);
                   10179: 
                   10180:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10181: 
                   10182:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10183:        const char funcName[] = "IsWow64Process";
                   10184:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10185:                GetProcAddress(module, funcName);
                   10186: 
                   10187:        if (NULL != fnIsWow64Process)
                   10188:        {
                   10189:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10190:                        &bIsWow64))
                   10191:                        //throw std::exception("Unknown error");
                   10192:                        printf("Unknown error\n");
                   10193:        }
                   10194:        return bIsWow64 != FALSE;
                   10195: }
                   10196: #endif
1.177     brouard  10197: 
1.191     brouard  10198: void syscompilerinfo(int logged)
1.167     brouard  10199:  {
                   10200:    /* #include "syscompilerinfo.h"*/
1.185     brouard  10201:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10202:    /* /GS /W3 /Gy
                   10203:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10204:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10205:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10206:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10207:    */ 
                   10208:    /* 64 bits */
1.185     brouard  10209:    /*
                   10210:      /GS /W3 /Gy
                   10211:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10212:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10213:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10214:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10215:    /* Optimization are useless and O3 is slower than O2 */
                   10216:    /*
                   10217:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10218:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10219:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10220:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10221:    */
1.186     brouard  10222:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10223:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10224:       /PDB:"visual studio
                   10225:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10226:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10227:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10228:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10229:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10230:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10231:       uiAccess='false'"
                   10232:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10233:       /NOLOGO /TLBID:1
                   10234:    */
1.177     brouard  10235: #if defined __INTEL_COMPILER
1.178     brouard  10236: #if defined(__GNUC__)
                   10237:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10238: #endif
1.177     brouard  10239: #elif defined(__GNUC__) 
1.179     brouard  10240: #ifndef  __APPLE__
1.174     brouard  10241: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10242: #endif
1.177     brouard  10243:    struct utsname sysInfo;
1.178     brouard  10244:    int cross = CROSS;
                   10245:    if (cross){
                   10246:           printf("Cross-");
1.191     brouard  10247:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10248:    }
1.174     brouard  10249: #endif
                   10250: 
1.171     brouard  10251: #include <stdint.h>
1.178     brouard  10252: 
1.191     brouard  10253:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10254: #if defined(__clang__)
1.191     brouard  10255:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10256: #endif
                   10257: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10258:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10259: #endif
                   10260: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10261:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10262: #endif
                   10263: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10264:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10265: #endif
                   10266: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10267:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10268: #endif
                   10269: #if defined(_MSC_VER)
1.191     brouard  10270:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10271: #endif
                   10272: #if defined(__PGI)
1.191     brouard  10273:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10274: #endif
                   10275: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10276:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10277: #endif
1.191     brouard  10278:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10279:    
1.167     brouard  10280: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10281: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10282:     // Windows (x64 and x86)
1.191     brouard  10283:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10284: #elif __unix__ // all unices, not all compilers
                   10285:     // Unix
1.191     brouard  10286:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10287: #elif __linux__
                   10288:     // linux
1.191     brouard  10289:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10290: #elif __APPLE__
1.174     brouard  10291:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10292:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10293: #endif
                   10294: 
                   10295: /*  __MINGW32__          */
                   10296: /*  __CYGWIN__  */
                   10297: /* __MINGW64__  */
                   10298: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10299: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10300: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10301: /* _WIN64  // Defined for applications for Win64. */
                   10302: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10303: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10304: 
1.167     brouard  10305: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10306:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10307: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10308:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10309: #else
1.191     brouard  10310:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10311: #endif
                   10312: 
1.169     brouard  10313: #if defined(__GNUC__)
                   10314: # if defined(__GNUC_PATCHLEVEL__)
                   10315: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10316:                             + __GNUC_MINOR__ * 100 \
                   10317:                             + __GNUC_PATCHLEVEL__)
                   10318: # else
                   10319: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10320:                             + __GNUC_MINOR__ * 100)
                   10321: # endif
1.174     brouard  10322:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10323:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10324: 
                   10325:    if (uname(&sysInfo) != -1) {
                   10326:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10327:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10328:    }
                   10329:    else
                   10330:       perror("uname() error");
1.179     brouard  10331:    //#ifndef __INTEL_COMPILER 
                   10332: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10333:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10334:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10335: #endif
1.169     brouard  10336: #endif
1.172     brouard  10337: 
1.286     brouard  10338:    //   void main ()
1.172     brouard  10339:    //   {
1.169     brouard  10340: #if defined(_MSC_VER)
1.174     brouard  10341:    if (IsWow64()){
1.191     brouard  10342:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10343:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10344:    }
                   10345:    else{
1.191     brouard  10346:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10347:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10348:    }
1.172     brouard  10349:    //     printf("\nPress Enter to continue...");
                   10350:    //     getchar();
                   10351:    //   }
                   10352: 
1.169     brouard  10353: #endif
                   10354:    
1.167     brouard  10355: 
1.219     brouard  10356: }
1.136     brouard  10357: 
1.219     brouard  10358: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10359:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10360:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10361:   /* double ftolpl = 1.e-10; */
1.180     brouard  10362:   double age, agebase, agelim;
1.203     brouard  10363:   double tot;
1.180     brouard  10364: 
1.202     brouard  10365:   strcpy(filerespl,"PL_");
                   10366:   strcat(filerespl,fileresu);
                   10367:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10368:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10369:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10370:   }
1.288     brouard  10371:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10372:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10373:   pstamp(ficrespl);
1.288     brouard  10374:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10375:   fprintf(ficrespl,"#Age ");
                   10376:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10377:   fprintf(ficrespl,"\n");
1.180     brouard  10378:   
1.219     brouard  10379:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10380: 
1.219     brouard  10381:   agebase=ageminpar;
                   10382:   agelim=agemaxpar;
1.180     brouard  10383: 
1.227     brouard  10384:   /* i1=pow(2,ncoveff); */
1.234     brouard  10385:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10386:   if (cptcovn < 1){i1=1;}
1.180     brouard  10387: 
1.238     brouard  10388:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10389:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10390:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10391:        continue;
1.235     brouard  10392: 
1.238     brouard  10393:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10394:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10395:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10396:       /* k=k+1; */
                   10397:       /* to clean */
                   10398:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10399:       fprintf(ficrespl,"#******");
                   10400:       printf("#******");
                   10401:       fprintf(ficlog,"#******");
                   10402:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10403:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10404:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10405:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10406:       }
                   10407:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10408:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10409:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10410:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10411:       }
                   10412:       fprintf(ficrespl,"******\n");
                   10413:       printf("******\n");
                   10414:       fprintf(ficlog,"******\n");
                   10415:       if(invalidvarcomb[k]){
                   10416:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10417:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10418:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10419:        continue;
                   10420:       }
1.219     brouard  10421: 
1.238     brouard  10422:       fprintf(ficrespl,"#Age ");
                   10423:       for(j=1;j<=cptcoveff;j++) {
                   10424:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10425:       }
                   10426:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10427:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10428:     
1.238     brouard  10429:       for (age=agebase; age<=agelim; age++){
                   10430:        /* for (age=agebase; age<=agebase; age++){ */
                   10431:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10432:        fprintf(ficrespl,"%.0f ",age );
                   10433:        for(j=1;j<=cptcoveff;j++)
                   10434:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10435:        tot=0.;
                   10436:        for(i=1; i<=nlstate;i++){
                   10437:          tot +=  prlim[i][i];
                   10438:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10439:        }
                   10440:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10441:       } /* Age */
                   10442:       /* was end of cptcod */
                   10443:     } /* cptcov */
                   10444:   } /* nres */
1.219     brouard  10445:   return 0;
1.180     brouard  10446: }
                   10447: 
1.218     brouard  10448: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10449:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10450:        
                   10451:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10452:    * at any age between ageminpar and agemaxpar
                   10453:         */
1.235     brouard  10454:   int i, j, k, i1, nres=0 ;
1.217     brouard  10455:   /* double ftolpl = 1.e-10; */
                   10456:   double age, agebase, agelim;
                   10457:   double tot;
1.218     brouard  10458:   /* double ***mobaverage; */
                   10459:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10460: 
                   10461:   strcpy(fileresplb,"PLB_");
                   10462:   strcat(fileresplb,fileresu);
                   10463:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10464:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10465:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10466:   }
1.288     brouard  10467:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10468:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10469:   pstamp(ficresplb);
1.288     brouard  10470:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10471:   fprintf(ficresplb,"#Age ");
                   10472:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10473:   fprintf(ficresplb,"\n");
                   10474:   
1.218     brouard  10475:   
                   10476:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10477:   
                   10478:   agebase=ageminpar;
                   10479:   agelim=agemaxpar;
                   10480:   
                   10481:   
1.227     brouard  10482:   i1=pow(2,cptcoveff);
1.218     brouard  10483:   if (cptcovn < 1){i1=1;}
1.227     brouard  10484:   
1.238     brouard  10485:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10486:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10487:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10488:        continue;
                   10489:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10490:       fprintf(ficresplb,"#******");
                   10491:       printf("#******");
                   10492:       fprintf(ficlog,"#******");
                   10493:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10494:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10495:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10496:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10497:       }
                   10498:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10499:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10500:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10501:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10502:       }
                   10503:       fprintf(ficresplb,"******\n");
                   10504:       printf("******\n");
                   10505:       fprintf(ficlog,"******\n");
                   10506:       if(invalidvarcomb[k]){
                   10507:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10508:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10509:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10510:        continue;
                   10511:       }
1.218     brouard  10512:     
1.238     brouard  10513:       fprintf(ficresplb,"#Age ");
                   10514:       for(j=1;j<=cptcoveff;j++) {
                   10515:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10516:       }
                   10517:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10518:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10519:     
                   10520:     
1.238     brouard  10521:       for (age=agebase; age<=agelim; age++){
                   10522:        /* for (age=agebase; age<=agebase; age++){ */
                   10523:        if(mobilavproj > 0){
                   10524:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10525:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10526:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10527:        }else if (mobilavproj == 0){
                   10528:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10529:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10530:          exit(1);
                   10531:        }else{
                   10532:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10533:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10534:          /* printf("TOTOT\n"); */
                   10535:           /* exit(1); */
1.238     brouard  10536:        }
                   10537:        fprintf(ficresplb,"%.0f ",age );
                   10538:        for(j=1;j<=cptcoveff;j++)
                   10539:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10540:        tot=0.;
                   10541:        for(i=1; i<=nlstate;i++){
                   10542:          tot +=  bprlim[i][i];
                   10543:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10544:        }
                   10545:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10546:       } /* Age */
                   10547:       /* was end of cptcod */
1.255     brouard  10548:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10549:     } /* end of any combination */
                   10550:   } /* end of nres */  
1.218     brouard  10551:   /* hBijx(p, bage, fage); */
                   10552:   /* fclose(ficrespijb); */
                   10553:   
                   10554:   return 0;
1.217     brouard  10555: }
1.218     brouard  10556:  
1.180     brouard  10557: int hPijx(double *p, int bage, int fage){
                   10558:     /*------------- h Pij x at various ages ------------*/
                   10559: 
                   10560:   int stepsize;
                   10561:   int agelim;
                   10562:   int hstepm;
                   10563:   int nhstepm;
1.235     brouard  10564:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10565: 
                   10566:   double agedeb;
                   10567:   double ***p3mat;
                   10568: 
1.201     brouard  10569:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10570:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10571:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10572:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10573:     }
                   10574:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10575:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10576:   
                   10577:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10578:     /*if (stepm<=24) stepsize=2;*/
                   10579: 
                   10580:     agelim=AGESUP;
                   10581:     hstepm=stepsize*YEARM; /* Every year of age */
                   10582:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10583:                
1.180     brouard  10584:     /* hstepm=1;   aff par mois*/
                   10585:     pstamp(ficrespij);
                   10586:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10587:     i1= pow(2,cptcoveff);
1.218     brouard  10588:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10589:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10590:                /*      k=k+1;  */
1.235     brouard  10591:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10592:     for(k=1; k<=i1;k++){
1.253     brouard  10593:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10594:        continue;
1.183     brouard  10595:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10596:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10597:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10598:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10599:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10600:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10601:       }
1.183     brouard  10602:       fprintf(ficrespij,"******\n");
                   10603:       
                   10604:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10605:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10606:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10607:        
                   10608:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10609:        
1.183     brouard  10610:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10611:        oldm=oldms;savm=savms;
1.235     brouard  10612:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10613:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10614:        for(i=1; i<=nlstate;i++)
                   10615:          for(j=1; j<=nlstate+ndeath;j++)
                   10616:            fprintf(ficrespij," %1d-%1d",i,j);
                   10617:        fprintf(ficrespij,"\n");
                   10618:        for (h=0; h<=nhstepm; h++){
                   10619:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10620:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10621:          for(i=1; i<=nlstate;i++)
                   10622:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10623:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10624:          fprintf(ficrespij,"\n");
                   10625:        }
1.183     brouard  10626:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10627:        fprintf(ficrespij,"\n");
                   10628:       }
1.180     brouard  10629:       /*}*/
                   10630:     }
1.218     brouard  10631:     return 0;
1.180     brouard  10632: }
1.218     brouard  10633:  
                   10634:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10635:     /*------------- h Bij x at various ages ------------*/
                   10636: 
                   10637:   int stepsize;
1.218     brouard  10638:   /* int agelim; */
                   10639:        int ageminl;
1.217     brouard  10640:   int hstepm;
                   10641:   int nhstepm;
1.238     brouard  10642:   int h, i, i1, j, k, nres;
1.218     brouard  10643:        
1.217     brouard  10644:   double agedeb;
                   10645:   double ***p3mat;
1.218     brouard  10646:        
                   10647:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10648:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10649:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10650:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10651:   }
                   10652:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10653:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10654:   
                   10655:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10656:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10657:   
1.218     brouard  10658:   /* agelim=AGESUP; */
1.289     brouard  10659:   ageminl=AGEINF; /* was 30 */
1.218     brouard  10660:   hstepm=stepsize*YEARM; /* Every year of age */
                   10661:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10662:   
                   10663:   /* hstepm=1;   aff par mois*/
                   10664:   pstamp(ficrespijb);
1.255     brouard  10665:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10666:   i1= pow(2,cptcoveff);
1.218     brouard  10667:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10668:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10669:   /*   k=k+1;  */
1.238     brouard  10670:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10671:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10672:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10673:        continue;
                   10674:       fprintf(ficrespijb,"\n#****** ");
                   10675:       for(j=1;j<=cptcoveff;j++)
                   10676:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10677:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10678:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10679:       }
                   10680:       fprintf(ficrespijb,"******\n");
1.264     brouard  10681:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10682:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10683:        continue;
                   10684:       }
                   10685:       
                   10686:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10687:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10688:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10689:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10690:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10691:        
                   10692:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10693:        
1.266     brouard  10694:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10695:        /* and memory limitations if stepm is small */
                   10696: 
1.238     brouard  10697:        /* oldm=oldms;savm=savms; */
                   10698:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10699:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10700:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10701:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10702:        for(i=1; i<=nlstate;i++)
                   10703:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10704:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10705:        fprintf(ficrespijb,"\n");
1.238     brouard  10706:        for (h=0; h<=nhstepm; h++){
                   10707:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10708:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10709:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10710:          for(i=1; i<=nlstate;i++)
                   10711:            for(j=1; j<=nlstate+ndeath;j++)
                   10712:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10713:          fprintf(ficrespijb,"\n");
                   10714:        }
                   10715:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10716:        fprintf(ficrespijb,"\n");
                   10717:       } /* end age deb */
                   10718:     } /* end combination */
                   10719:   } /* end nres */
1.218     brouard  10720:   return 0;
                   10721:  } /*  hBijx */
1.217     brouard  10722: 
1.180     brouard  10723: 
1.136     brouard  10724: /***********************************************/
                   10725: /**************** Main Program *****************/
                   10726: /***********************************************/
                   10727: 
                   10728: int main(int argc, char *argv[])
                   10729: {
                   10730: #ifdef GSL
                   10731:   const gsl_multimin_fminimizer_type *T;
                   10732:   size_t iteri = 0, it;
                   10733:   int rval = GSL_CONTINUE;
                   10734:   int status = GSL_SUCCESS;
                   10735:   double ssval;
                   10736: #endif
                   10737:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  10738:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   10739:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  10740:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10741:   int jj, ll, li, lj, lk;
1.136     brouard  10742:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10743:   int num_filled;
1.136     brouard  10744:   int itimes;
                   10745:   int NDIM=2;
                   10746:   int vpopbased=0;
1.235     brouard  10747:   int nres=0;
1.258     brouard  10748:   int endishere=0;
1.277     brouard  10749:   int noffset=0;
1.274     brouard  10750:   int ncurrv=0; /* Temporary variable */
                   10751:   
1.164     brouard  10752:   char ca[32], cb[32];
1.136     brouard  10753:   /*  FILE *fichtm; *//* Html File */
                   10754:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10755:   struct stat info;
1.191     brouard  10756:   double agedeb=0.;
1.194     brouard  10757: 
                   10758:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10759:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10760: 
1.165     brouard  10761:   double fret;
1.191     brouard  10762:   double dum=0.; /* Dummy variable */
1.136     brouard  10763:   double ***p3mat;
1.218     brouard  10764:   /* double ***mobaverage; */
1.164     brouard  10765: 
                   10766:   char line[MAXLINE];
1.197     brouard  10767:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10768: 
1.234     brouard  10769:   char  modeltemp[MAXLINE];
1.230     brouard  10770:   char resultline[MAXLINE];
                   10771:   
1.136     brouard  10772:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10773:   char *tok, *val; /* pathtot */
1.290     brouard  10774:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  10775:   int c,  h , cpt, c2;
1.191     brouard  10776:   int jl=0;
                   10777:   int i1, j1, jk, stepsize=0;
1.194     brouard  10778:   int count=0;
                   10779: 
1.164     brouard  10780:   int *tab; 
1.136     brouard  10781:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.217     brouard  10782:   int backcast=0;
1.136     brouard  10783:   int mobilav=0,popforecast=0;
1.191     brouard  10784:   int hstepm=0, nhstepm=0;
1.136     brouard  10785:   int agemortsup;
                   10786:   float  sumlpop=0.;
                   10787:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10788:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10789: 
1.191     brouard  10790:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10791:   double ftolpl=FTOL;
                   10792:   double **prlim;
1.217     brouard  10793:   double **bprlim;
1.136     brouard  10794:   double ***param; /* Matrix of parameters */
1.251     brouard  10795:   double ***paramstart; /* Matrix of starting parameter values */
                   10796:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10797:   double **matcov; /* Matrix of covariance */
1.203     brouard  10798:   double **hess; /* Hessian matrix */
1.136     brouard  10799:   double ***delti3; /* Scale */
                   10800:   double *delti; /* Scale */
                   10801:   double ***eij, ***vareij;
                   10802:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10803: 
1.136     brouard  10804:   double *epj, vepp;
1.164     brouard  10805: 
1.273     brouard  10806:   double dateprev1, dateprev2;
                   10807:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0;
                   10808:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0;
1.217     brouard  10809: 
1.136     brouard  10810:   double **ximort;
1.145     brouard  10811:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10812:   int *dcwave;
                   10813: 
1.164     brouard  10814:   char z[1]="c";
1.136     brouard  10815: 
                   10816:   /*char  *strt;*/
                   10817:   char strtend[80];
1.126     brouard  10818: 
1.164     brouard  10819: 
1.126     brouard  10820: /*   setlocale (LC_ALL, ""); */
                   10821: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10822: /*   textdomain (PACKAGE); */
                   10823: /*   setlocale (LC_CTYPE, ""); */
                   10824: /*   setlocale (LC_MESSAGES, ""); */
                   10825: 
                   10826:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10827:   rstart_time = time(NULL);  
                   10828:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10829:   start_time = *localtime(&rstart_time);
1.126     brouard  10830:   curr_time=start_time;
1.157     brouard  10831:   /*tml = *localtime(&start_time.tm_sec);*/
                   10832:   /* strcpy(strstart,asctime(&tml)); */
                   10833:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10834: 
                   10835: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10836: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10837: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10838: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10839: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10840: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10841: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10842: /*   strt=asctime(&tmg); */
                   10843: /*   printf("Time(after) =%s",strstart);  */
                   10844: /*  (void) time (&time_value);
                   10845: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10846: *  tm = *localtime(&time_value);
                   10847: *  strstart=asctime(&tm);
                   10848: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10849: */
                   10850: 
                   10851:   nberr=0; /* Number of errors and warnings */
                   10852:   nbwarn=0;
1.184     brouard  10853: #ifdef WIN32
                   10854:   _getcwd(pathcd, size);
                   10855: #else
1.126     brouard  10856:   getcwd(pathcd, size);
1.184     brouard  10857: #endif
1.191     brouard  10858:   syscompilerinfo(0);
1.196     brouard  10859:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10860:   if(argc <=1){
                   10861:     printf("\nEnter the parameter file name: ");
1.205     brouard  10862:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10863:       printf("ERROR Empty parameter file name\n");
                   10864:       goto end;
                   10865:     }
1.126     brouard  10866:     i=strlen(pathr);
                   10867:     if(pathr[i-1]=='\n')
                   10868:       pathr[i-1]='\0';
1.156     brouard  10869:     i=strlen(pathr);
1.205     brouard  10870:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10871:       pathr[i-1]='\0';
1.205     brouard  10872:     }
                   10873:     i=strlen(pathr);
                   10874:     if( i==0 ){
                   10875:       printf("ERROR Empty parameter file name\n");
                   10876:       goto end;
                   10877:     }
                   10878:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10879:       printf("Pathr |%s|\n",pathr);
                   10880:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10881:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10882:       strcpy (pathtot, val);
                   10883:       if(pathr[0] == '\0') break; /* Dirty */
                   10884:     }
                   10885:   }
1.281     brouard  10886:   else if (argc<=2){
                   10887:     strcpy(pathtot,argv[1]);
                   10888:   }
1.126     brouard  10889:   else{
                   10890:     strcpy(pathtot,argv[1]);
1.281     brouard  10891:     strcpy(z,argv[2]);
                   10892:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  10893:   }
                   10894:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10895:   /*cygwin_split_path(pathtot,path,optionfile);
                   10896:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10897:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10898: 
                   10899:   /* Split argv[0], imach program to get pathimach */
                   10900:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10901:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10902:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10903:  /*   strcpy(pathimach,argv[0]); */
                   10904:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10905:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10906:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10907: #ifdef WIN32
                   10908:   _chdir(path); /* Can be a relative path */
                   10909:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10910: #else
1.126     brouard  10911:   chdir(path); /* Can be a relative path */
1.184     brouard  10912:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10913: #endif
                   10914:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10915:   strcpy(command,"mkdir ");
                   10916:   strcat(command,optionfilefiname);
                   10917:   if((outcmd=system(command)) != 0){
1.169     brouard  10918:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10919:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10920:     /* fclose(ficlog); */
                   10921: /*     exit(1); */
                   10922:   }
                   10923: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10924: /*     perror("mkdir"); */
                   10925: /*   } */
                   10926: 
                   10927:   /*-------- arguments in the command line --------*/
                   10928: 
1.186     brouard  10929:   /* Main Log file */
1.126     brouard  10930:   strcat(filelog, optionfilefiname);
                   10931:   strcat(filelog,".log");    /* */
                   10932:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10933:     printf("Problem with logfile %s\n",filelog);
                   10934:     goto end;
                   10935:   }
                   10936:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10937:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10938:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10939:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10940:  path=%s \n\
                   10941:  optionfile=%s\n\
                   10942:  optionfilext=%s\n\
1.156     brouard  10943:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10944: 
1.197     brouard  10945:   syscompilerinfo(1);
1.167     brouard  10946: 
1.126     brouard  10947:   printf("Local time (at start):%s",strstart);
                   10948:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10949:   fflush(ficlog);
                   10950: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10951: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10952: 
                   10953:   /* */
                   10954:   strcpy(fileres,"r");
                   10955:   strcat(fileres, optionfilefiname);
1.201     brouard  10956:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10957:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10958:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10959: 
1.186     brouard  10960:   /* Main ---------arguments file --------*/
1.126     brouard  10961: 
                   10962:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10963:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10964:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10965:     fflush(ficlog);
1.149     brouard  10966:     /* goto end; */
                   10967:     exit(70); 
1.126     brouard  10968:   }
                   10969: 
                   10970:   strcpy(filereso,"o");
1.201     brouard  10971:   strcat(filereso,fileresu);
1.126     brouard  10972:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10973:     printf("Problem with Output resultfile: %s\n", filereso);
                   10974:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10975:     fflush(ficlog);
                   10976:     goto end;
                   10977:   }
1.278     brouard  10978:       /*-------- Rewriting parameter file ----------*/
                   10979:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   10980:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   10981:   strcat(rfileres,".");    /* */
                   10982:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10983:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   10984:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10985:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   10986:     fflush(ficlog);
                   10987:     goto end;
                   10988:   }
                   10989:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  10990: 
1.278     brouard  10991:                                      
1.126     brouard  10992:   /* Reads comments: lines beginning with '#' */
                   10993:   numlinepar=0;
1.277     brouard  10994:   /* Is it a BOM UTF-8 Windows file? */
                   10995:   /* First parameter line */
1.197     brouard  10996:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  10997:     noffset=0;
                   10998:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   10999:     {
                   11000:       noffset=noffset+3;
                   11001:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11002:     }
                   11003:     else if( line[0] == (char)0xFE && line[1] == (char)0xFF)
                   11004:     {
                   11005:       noffset=noffset+2;
                   11006:       printf("# File is an UTF16BE BOM file\n");
                   11007:     }
                   11008:     else if( line[0] == 0 && line[1] == 0)
                   11009:     {
                   11010:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11011:        noffset=noffset+4;
                   11012:        printf("# File is an UTF16BE BOM file\n");
                   11013:       }
                   11014:     } else{
                   11015:       ;/*printf(" Not a BOM file\n");*/
                   11016:     }
                   11017:   
1.197     brouard  11018:     /* If line starts with a # it is a comment */
1.277     brouard  11019:     if (line[noffset] == '#') {
1.197     brouard  11020:       numlinepar++;
                   11021:       fputs(line,stdout);
                   11022:       fputs(line,ficparo);
1.278     brouard  11023:       fputs(line,ficres);
1.197     brouard  11024:       fputs(line,ficlog);
                   11025:       continue;
                   11026:     }else
                   11027:       break;
                   11028:   }
                   11029:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11030:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11031:     if (num_filled != 5) {
                   11032:       printf("Should be 5 parameters\n");
1.283     brouard  11033:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11034:     }
1.126     brouard  11035:     numlinepar++;
1.197     brouard  11036:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11037:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11038:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11039:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11040:   }
                   11041:   /* Second parameter line */
                   11042:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11043:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11044:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11045:     if (line[0] == '#') {
                   11046:       numlinepar++;
1.283     brouard  11047:       printf("%s",line);
                   11048:       fprintf(ficres,"%s",line);
                   11049:       fprintf(ficparo,"%s",line);
                   11050:       fprintf(ficlog,"%s",line);
1.197     brouard  11051:       continue;
                   11052:     }else
                   11053:       break;
                   11054:   }
1.223     brouard  11055:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11056:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11057:     if (num_filled != 11) {
                   11058:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11059:       printf("but line=%s\n",line);
1.283     brouard  11060:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11061:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11062:     }
1.286     brouard  11063:     if( lastpass > maxwav){
                   11064:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11065:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11066:       fflush(ficlog);
                   11067:       goto end;
                   11068:     }
                   11069:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11070:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11071:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11072:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11073:   }
1.203     brouard  11074:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11075:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11076:   /* Third parameter line */
                   11077:   while(fgets(line, MAXLINE, ficpar)) {
                   11078:     /* If line starts with a # it is a comment */
                   11079:     if (line[0] == '#') {
                   11080:       numlinepar++;
1.283     brouard  11081:       printf("%s",line);
                   11082:       fprintf(ficres,"%s",line);
                   11083:       fprintf(ficparo,"%s",line);
                   11084:       fprintf(ficlog,"%s",line);
1.197     brouard  11085:       continue;
                   11086:     }else
                   11087:       break;
                   11088:   }
1.201     brouard  11089:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11090:     if (num_filled != 1){
                   11091:       printf("ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
                   11092:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
1.197     brouard  11093:       model[0]='\0';
                   11094:       goto end;
                   11095:     }
                   11096:     else{
                   11097:       if (model[0]=='+'){
                   11098:        for(i=1; i<=strlen(model);i++)
                   11099:          modeltemp[i-1]=model[i];
1.201     brouard  11100:        strcpy(model,modeltemp); 
1.197     brouard  11101:       }
                   11102:     }
1.199     brouard  11103:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11104:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11105:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11106:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11107:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11108:   }
                   11109:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11110:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11111:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11112:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11113:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11114:   fflush(ficlog);
1.190     brouard  11115:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11116:   if(model[0]=='#'){
1.279     brouard  11117:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11118:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11119:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11120:     if(mle != -1){
1.279     brouard  11121:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11122:       exit(1);
                   11123:     }
                   11124:   }
1.126     brouard  11125:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11126:     ungetc(c,ficpar);
                   11127:     fgets(line, MAXLINE, ficpar);
                   11128:     numlinepar++;
1.195     brouard  11129:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11130:       z[0]=line[1];
                   11131:     }
                   11132:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11133:     fputs(line, stdout);
                   11134:     //puts(line);
1.126     brouard  11135:     fputs(line,ficparo);
                   11136:     fputs(line,ficlog);
                   11137:   }
                   11138:   ungetc(c,ficpar);
                   11139: 
                   11140:    
1.290     brouard  11141:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11142:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11143:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11144:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11145:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11146:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11147:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11148:   */
                   11149:   if (strlen(model)>1) 
1.187     brouard  11150:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11151:   else
1.187     brouard  11152:     ncovmodel=2; /* Constant and age */
1.133     brouard  11153:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11154:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11155:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11156:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11157:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11158:     fflush(stdout);
                   11159:     fclose (ficlog);
                   11160:     goto end;
                   11161:   }
1.126     brouard  11162:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11163:   delti=delti3[1][1];
                   11164:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11165:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11166: /* We could also provide initial parameters values giving by simple logistic regression 
                   11167:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11168:       /* for(i=1;i<nlstate;i++){ */
                   11169:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11170:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11171:       /* } */
1.126     brouard  11172:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11173:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11174:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11175:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11176:     fclose (ficparo);
                   11177:     fclose (ficlog);
                   11178:     goto end;
                   11179:     exit(0);
1.220     brouard  11180:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11181:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11182:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11183:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11184:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11185:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11186:     hess=matrix(1,npar,1,npar);
1.220     brouard  11187:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11188:     /* Read guessed parameters */
1.126     brouard  11189:     /* Reads comments: lines beginning with '#' */
                   11190:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11191:       ungetc(c,ficpar);
                   11192:       fgets(line, MAXLINE, ficpar);
                   11193:       numlinepar++;
1.141     brouard  11194:       fputs(line,stdout);
1.126     brouard  11195:       fputs(line,ficparo);
                   11196:       fputs(line,ficlog);
                   11197:     }
                   11198:     ungetc(c,ficpar);
                   11199:     
                   11200:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11201:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11202:     for(i=1; i <=nlstate; i++){
1.234     brouard  11203:       j=0;
1.126     brouard  11204:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11205:        if(jj==i) continue;
                   11206:        j++;
                   11207:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11208:        if ((i1 != i) || (j1 != jj)){
                   11209:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11210: It might be a problem of design; if ncovcol and the model are correct\n \
                   11211: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11212:          exit(1);
                   11213:        }
                   11214:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11215:        if(mle==1)
                   11216:          printf("%1d%1d",i,jj);
                   11217:        fprintf(ficlog,"%1d%1d",i,jj);
                   11218:        for(k=1; k<=ncovmodel;k++){
                   11219:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11220:          if(mle==1){
                   11221:            printf(" %lf",param[i][j][k]);
                   11222:            fprintf(ficlog," %lf",param[i][j][k]);
                   11223:          }
                   11224:          else
                   11225:            fprintf(ficlog," %lf",param[i][j][k]);
                   11226:          fprintf(ficparo," %lf",param[i][j][k]);
                   11227:        }
                   11228:        fscanf(ficpar,"\n");
                   11229:        numlinepar++;
                   11230:        if(mle==1)
                   11231:          printf("\n");
                   11232:        fprintf(ficlog,"\n");
                   11233:        fprintf(ficparo,"\n");
1.126     brouard  11234:       }
                   11235:     }  
                   11236:     fflush(ficlog);
1.234     brouard  11237:     
1.251     brouard  11238:     /* Reads parameters values */
1.126     brouard  11239:     p=param[1][1];
1.251     brouard  11240:     pstart=paramstart[1][1];
1.126     brouard  11241:     
                   11242:     /* Reads comments: lines beginning with '#' */
                   11243:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11244:       ungetc(c,ficpar);
                   11245:       fgets(line, MAXLINE, ficpar);
                   11246:       numlinepar++;
1.141     brouard  11247:       fputs(line,stdout);
1.126     brouard  11248:       fputs(line,ficparo);
                   11249:       fputs(line,ficlog);
                   11250:     }
                   11251:     ungetc(c,ficpar);
                   11252: 
                   11253:     for(i=1; i <=nlstate; i++){
                   11254:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11255:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11256:        if ( (i1-i) * (j1-j) != 0){
                   11257:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11258:          exit(1);
                   11259:        }
                   11260:        printf("%1d%1d",i,j);
                   11261:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11262:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11263:        for(k=1; k<=ncovmodel;k++){
                   11264:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11265:          printf(" %le",delti3[i][j][k]);
                   11266:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11267:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11268:        }
                   11269:        fscanf(ficpar,"\n");
                   11270:        numlinepar++;
                   11271:        printf("\n");
                   11272:        fprintf(ficparo,"\n");
                   11273:        fprintf(ficlog,"\n");
1.126     brouard  11274:       }
                   11275:     }
                   11276:     fflush(ficlog);
1.234     brouard  11277:     
1.145     brouard  11278:     /* Reads covariance matrix */
1.126     brouard  11279:     delti=delti3[1][1];
1.220     brouard  11280:                
                   11281:                
1.126     brouard  11282:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11283:                
1.126     brouard  11284:     /* Reads comments: lines beginning with '#' */
                   11285:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11286:       ungetc(c,ficpar);
                   11287:       fgets(line, MAXLINE, ficpar);
                   11288:       numlinepar++;
1.141     brouard  11289:       fputs(line,stdout);
1.126     brouard  11290:       fputs(line,ficparo);
                   11291:       fputs(line,ficlog);
                   11292:     }
                   11293:     ungetc(c,ficpar);
1.220     brouard  11294:                
1.126     brouard  11295:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11296:     hess=matrix(1,npar,1,npar);
1.131     brouard  11297:     for(i=1; i <=npar; i++)
                   11298:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11299:                
1.194     brouard  11300:     /* Scans npar lines */
1.126     brouard  11301:     for(i=1; i <=npar; i++){
1.226     brouard  11302:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11303:       if(count != 3){
1.226     brouard  11304:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11305: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11306: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11307:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11308: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11309: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11310:        exit(1);
1.220     brouard  11311:       }else{
1.226     brouard  11312:        if(mle==1)
                   11313:          printf("%1d%1d%d",i1,j1,jk);
                   11314:       }
                   11315:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11316:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11317:       for(j=1; j <=i; j++){
1.226     brouard  11318:        fscanf(ficpar," %le",&matcov[i][j]);
                   11319:        if(mle==1){
                   11320:          printf(" %.5le",matcov[i][j]);
                   11321:        }
                   11322:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11323:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11324:       }
                   11325:       fscanf(ficpar,"\n");
                   11326:       numlinepar++;
                   11327:       if(mle==1)
1.220     brouard  11328:                                printf("\n");
1.126     brouard  11329:       fprintf(ficlog,"\n");
                   11330:       fprintf(ficparo,"\n");
                   11331:     }
1.194     brouard  11332:     /* End of read covariance matrix npar lines */
1.126     brouard  11333:     for(i=1; i <=npar; i++)
                   11334:       for(j=i+1;j<=npar;j++)
1.226     brouard  11335:        matcov[i][j]=matcov[j][i];
1.126     brouard  11336:     
                   11337:     if(mle==1)
                   11338:       printf("\n");
                   11339:     fprintf(ficlog,"\n");
                   11340:     
                   11341:     fflush(ficlog);
                   11342:     
                   11343:   }    /* End of mle != -3 */
1.218     brouard  11344:   
1.186     brouard  11345:   /*  Main data
                   11346:    */
1.290     brouard  11347:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11348:   /* num=lvector(1,n); */
                   11349:   /* moisnais=vector(1,n); */
                   11350:   /* annais=vector(1,n); */
                   11351:   /* moisdc=vector(1,n); */
                   11352:   /* andc=vector(1,n); */
                   11353:   /* weight=vector(1,n); */
                   11354:   /* agedc=vector(1,n); */
                   11355:   /* cod=ivector(1,n); */
                   11356:   /* for(i=1;i<=n;i++){ */
                   11357:   num=lvector(firstobs,lastobs);
                   11358:   moisnais=vector(firstobs,lastobs);
                   11359:   annais=vector(firstobs,lastobs);
                   11360:   moisdc=vector(firstobs,lastobs);
                   11361:   andc=vector(firstobs,lastobs);
                   11362:   weight=vector(firstobs,lastobs);
                   11363:   agedc=vector(firstobs,lastobs);
                   11364:   cod=ivector(firstobs,lastobs);
                   11365:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11366:     num[i]=0;
                   11367:     moisnais[i]=0;
                   11368:     annais[i]=0;
                   11369:     moisdc[i]=0;
                   11370:     andc[i]=0;
                   11371:     agedc[i]=0;
                   11372:     cod[i]=0;
                   11373:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11374:   }
1.290     brouard  11375:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11376:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11377:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11378:   tab=ivector(1,NCOVMAX);
1.144     brouard  11379:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11380:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11381: 
1.136     brouard  11382:   /* Reads data from file datafile */
                   11383:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11384:     goto end;
                   11385: 
                   11386:   /* Calculation of the number of parameters from char model */
1.234     brouard  11387:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11388:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11389:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11390:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11391:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11392:   */
                   11393:   
                   11394:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11395:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11396:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11397:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11398:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11399:   TvarF=ivector(1,NCOVMAX); /*  */
                   11400:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11401:   TvarV=ivector(1,NCOVMAX); /*  */
                   11402:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11403:   TvarA=ivector(1,NCOVMAX); /*  */
                   11404:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11405:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11406:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11407:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11408:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11409:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11410:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11411:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11412:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11413: 
1.230     brouard  11414:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11415:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11416:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11417:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11418:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11419:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11420:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11421:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11422:   */
                   11423:   /* For model-covariate k tells which data-covariate to use but
                   11424:     because this model-covariate is a construction we invent a new column
                   11425:     ncovcol + k1
                   11426:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11427:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11428:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11429:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11430:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11431:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11432:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11433:   */
1.145     brouard  11434:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11435:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11436:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11437:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11438:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11439:                         4 covariates (3 plus signs)
                   11440:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11441:                      */  
1.230     brouard  11442:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11443:                                * individual dummy, fixed or varying:
                   11444:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11445:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11446:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11447:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11448:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11449:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11450:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11451:                                * individual quantitative, fixed or varying:
                   11452:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11453:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11454:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11455: /* Main decodemodel */
                   11456: 
1.187     brouard  11457: 
1.223     brouard  11458:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11459:     goto end;
                   11460: 
1.137     brouard  11461:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11462:     nbwarn++;
                   11463:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11464:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11465:   }
1.136     brouard  11466:     /*  if(mle==1){*/
1.137     brouard  11467:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11468:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11469:   }
                   11470: 
                   11471:     /*-calculation of age at interview from date of interview and age at death -*/
                   11472:   agev=matrix(1,maxwav,1,imx);
                   11473: 
                   11474:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11475:     goto end;
                   11476: 
1.126     brouard  11477: 
1.136     brouard  11478:   agegomp=(int)agemin;
1.290     brouard  11479:   free_vector(moisnais,firstobs,lastobs);
                   11480:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11481:   /* free_matrix(mint,1,maxwav,1,n);
                   11482:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11483:   /* free_vector(moisdc,1,n); */
                   11484:   /* free_vector(andc,1,n); */
1.145     brouard  11485:   /* */
                   11486:   
1.126     brouard  11487:   wav=ivector(1,imx);
1.214     brouard  11488:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11489:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11490:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11491:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11492:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11493:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11494:    
                   11495:   /* Concatenates waves */
1.214     brouard  11496:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11497:      Death is a valid wave (if date is known).
                   11498:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11499:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11500:      and mw[mi+1][i]. dh depends on stepm.
                   11501:   */
                   11502: 
1.126     brouard  11503:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11504:   /* Concatenates waves */
1.145     brouard  11505:  
1.290     brouard  11506:   free_vector(moisdc,firstobs,lastobs);
                   11507:   free_vector(andc,firstobs,lastobs);
1.215     brouard  11508: 
1.126     brouard  11509:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11510:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11511:   ncodemax[1]=1;
1.145     brouard  11512:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11513:   cptcoveff=0;
1.220     brouard  11514:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11515:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11516:   }
                   11517:   
                   11518:   ncovcombmax=pow(2,cptcoveff);
                   11519:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11520:   for(i=1;i<ncovcombmax;i++)
                   11521:     invalidvarcomb[i]=0;
                   11522:   
1.211     brouard  11523:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11524:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11525:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11526:   
1.200     brouard  11527:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11528:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11529:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11530:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11531:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11532:    * (currently 0 or 1) in the data.
                   11533:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11534:    * corresponding modality (h,j).
                   11535:    */
                   11536: 
1.145     brouard  11537:   h=0;
                   11538:   /*if (cptcovn > 0) */
1.126     brouard  11539:   m=pow(2,cptcoveff);
                   11540:  
1.144     brouard  11541:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11542:           * For k=4 covariates, h goes from 1 to m=2**k
                   11543:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11544:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11545:           *     h\k   1     2     3     4
1.143     brouard  11546:           *______________________________  
                   11547:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11548:           *     2     2     1     1     1
                   11549:           *     3 i=2 1     2     1     1
                   11550:           *     4     2     2     1     1
                   11551:           *     5 i=3 1 i=2 1     2     1
                   11552:           *     6     2     1     2     1
                   11553:           *     7 i=4 1     2     2     1
                   11554:           *     8     2     2     2     1
1.197     brouard  11555:           *     9 i=5 1 i=3 1 i=2 1     2
                   11556:           *    10     2     1     1     2
                   11557:           *    11 i=6 1     2     1     2
                   11558:           *    12     2     2     1     2
                   11559:           *    13 i=7 1 i=4 1     2     2    
                   11560:           *    14     2     1     2     2
                   11561:           *    15 i=8 1     2     2     2
                   11562:           *    16     2     2     2     2
1.143     brouard  11563:           */
1.212     brouard  11564:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11565:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11566:      * and the value of each covariate?
                   11567:      * V1=1, V2=1, V3=2, V4=1 ?
                   11568:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11569:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11570:      * In order to get the real value in the data, we use nbcode
                   11571:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11572:      * We are keeping this crazy system in order to be able (in the future?) 
                   11573:      * to have more than 2 values (0 or 1) for a covariate.
                   11574:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11575:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11576:      *              bbbbbbbb
                   11577:      *              76543210     
                   11578:      *   h-1        00000101 (6-1=5)
1.219     brouard  11579:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11580:      *           &
                   11581:      *     1        00000001 (1)
1.219     brouard  11582:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11583:      *          +1= 00000001 =1 
1.211     brouard  11584:      *
                   11585:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11586:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11587:      *    >>k'            11
                   11588:      *          &   00000001
                   11589:      *            = 00000001
                   11590:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11591:      * Reverse h=6 and m=16?
                   11592:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11593:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11594:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11595:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11596:      * V3=decodtabm(14,3,2**4)=2
                   11597:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11598:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11599:      *          &1 000000001
                   11600:      *           = 000000001
                   11601:      *         +1= 000000010 =2
                   11602:      *                  2211
                   11603:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11604:      *                  V3=2
1.220     brouard  11605:                 * codtabm and decodtabm are identical
1.211     brouard  11606:      */
                   11607: 
1.145     brouard  11608: 
                   11609:  free_ivector(Ndum,-1,NCOVMAX);
                   11610: 
                   11611: 
1.126     brouard  11612:     
1.186     brouard  11613:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11614:   strcpy(optionfilegnuplot,optionfilefiname);
                   11615:   if(mle==-3)
1.201     brouard  11616:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11617:   strcat(optionfilegnuplot,".gp");
                   11618: 
                   11619:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11620:     printf("Problem with file %s",optionfilegnuplot);
                   11621:   }
                   11622:   else{
1.204     brouard  11623:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11624:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11625:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11626:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11627:   }
                   11628:   /*  fclose(ficgp);*/
1.186     brouard  11629: 
                   11630: 
                   11631:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11632: 
                   11633:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11634:   if(mle==-3)
1.201     brouard  11635:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11636:   strcat(optionfilehtm,".htm");
                   11637:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11638:     printf("Problem with %s \n",optionfilehtm);
                   11639:     exit(0);
1.126     brouard  11640:   }
                   11641: 
                   11642:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11643:   strcat(optionfilehtmcov,"-cov.htm");
                   11644:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11645:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11646:   }
                   11647:   else{
                   11648:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11649: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11650: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11651:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11652:   }
                   11653: 
1.213     brouard  11654:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11655: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11656: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11657: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11658: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11659: \n\
                   11660: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11661:  <ul><li><h4>Parameter files</h4>\n\
                   11662:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11663:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11664:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11665:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11666:  - Date and time at start: %s</ul>\n",\
                   11667:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11668:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11669:          fileres,fileres,\
                   11670:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11671:   fflush(fichtm);
                   11672: 
                   11673:   strcpy(pathr,path);
                   11674:   strcat(pathr,optionfilefiname);
1.184     brouard  11675: #ifdef WIN32
                   11676:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11677: #else
1.126     brouard  11678:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11679: #endif
                   11680:          
1.126     brouard  11681:   
1.220     brouard  11682:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11683:                 and for any valid combination of covariates
1.126     brouard  11684:      and prints on file fileres'p'. */
1.251     brouard  11685:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11686:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11687: 
                   11688:   fprintf(fichtm,"\n");
1.286     brouard  11689:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11690:          ftol, stepm);
                   11691:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11692:   ncurrv=1;
                   11693:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11694:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11695:   ncurrv=i;
                   11696:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11697:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  11698:   ncurrv=i;
                   11699:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11700:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  11701:   ncurrv=i;
                   11702:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11703:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11704:           nlstate, ndeath, maxwav, mle, weightopt);
                   11705: 
                   11706:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11707: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11708: 
                   11709:   
                   11710:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11711: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11712: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11713:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11714:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11715:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11716:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11717:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11718:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11719: 
1.126     brouard  11720:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11721:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11722:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11723: 
                   11724:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11725:   /* For mortality only */
1.126     brouard  11726:   if (mle==-3){
1.136     brouard  11727:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11728:     for(i=1;i<=NDIM;i++)
                   11729:       for(j=1;j<=NDIM;j++)
                   11730:        ximort[i][j]=0.;
1.186     brouard  11731:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  11732:     cens=ivector(firstobs,lastobs);
                   11733:     ageexmed=vector(firstobs,lastobs);
                   11734:     agecens=vector(firstobs,lastobs);
                   11735:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  11736:                
1.126     brouard  11737:     for (i=1; i<=imx; i++){
                   11738:       dcwave[i]=-1;
                   11739:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11740:        if (s[m][i]>nlstate) {
                   11741:          dcwave[i]=m;
                   11742:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11743:          break;
                   11744:        }
1.126     brouard  11745:     }
1.226     brouard  11746:     
1.126     brouard  11747:     for (i=1; i<=imx; i++) {
                   11748:       if (wav[i]>0){
1.226     brouard  11749:        ageexmed[i]=agev[mw[1][i]][i];
                   11750:        j=wav[i];
                   11751:        agecens[i]=1.; 
                   11752:        
                   11753:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11754:          agecens[i]=agev[mw[j][i]][i];
                   11755:          cens[i]= 1;
                   11756:        }else if (ageexmed[i]< 1) 
                   11757:          cens[i]= -1;
                   11758:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11759:          cens[i]=0 ;
1.126     brouard  11760:       }
                   11761:       else cens[i]=-1;
                   11762:     }
                   11763:     
                   11764:     for (i=1;i<=NDIM;i++) {
                   11765:       for (j=1;j<=NDIM;j++)
1.226     brouard  11766:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11767:     }
                   11768:     
1.145     brouard  11769:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11770:     /*printf("%lf %lf", p[1], p[2]);*/
                   11771:     
                   11772:     
1.136     brouard  11773: #ifdef GSL
                   11774:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11775: #else
1.126     brouard  11776:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11777: #endif
1.201     brouard  11778:     strcpy(filerespow,"POW-MORT_"); 
                   11779:     strcat(filerespow,fileresu);
1.126     brouard  11780:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11781:       printf("Problem with resultfile: %s\n", filerespow);
                   11782:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11783:     }
1.136     brouard  11784: #ifdef GSL
                   11785:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11786: #else
1.126     brouard  11787:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11788: #endif
1.126     brouard  11789:     /*  for (i=1;i<=nlstate;i++)
                   11790:        for(j=1;j<=nlstate+ndeath;j++)
                   11791:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11792:     */
                   11793:     fprintf(ficrespow,"\n");
1.136     brouard  11794: #ifdef GSL
                   11795:     /* gsl starts here */ 
                   11796:     T = gsl_multimin_fminimizer_nmsimplex;
                   11797:     gsl_multimin_fminimizer *sfm = NULL;
                   11798:     gsl_vector *ss, *x;
                   11799:     gsl_multimin_function minex_func;
                   11800: 
                   11801:     /* Initial vertex size vector */
                   11802:     ss = gsl_vector_alloc (NDIM);
                   11803:     
                   11804:     if (ss == NULL){
                   11805:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11806:     }
                   11807:     /* Set all step sizes to 1 */
                   11808:     gsl_vector_set_all (ss, 0.001);
                   11809: 
                   11810:     /* Starting point */
1.126     brouard  11811:     
1.136     brouard  11812:     x = gsl_vector_alloc (NDIM);
                   11813:     
                   11814:     if (x == NULL){
                   11815:       gsl_vector_free(ss);
                   11816:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11817:     }
                   11818:   
                   11819:     /* Initialize method and iterate */
                   11820:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11821:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11822:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11823:     gsl_vector_set(x, 0, p[1]);
                   11824:     gsl_vector_set(x, 1, p[2]);
                   11825: 
                   11826:     minex_func.f = &gompertz_f;
                   11827:     minex_func.n = NDIM;
                   11828:     minex_func.params = (void *)&p; /* ??? */
                   11829:     
                   11830:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11831:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11832:     
                   11833:     printf("Iterations beginning .....\n\n");
                   11834:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11835: 
                   11836:     iteri=0;
                   11837:     while (rval == GSL_CONTINUE){
                   11838:       iteri++;
                   11839:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11840:       
                   11841:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11842:       fflush(0);
                   11843:       
                   11844:       if (status) 
                   11845:         break;
                   11846:       
                   11847:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11848:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11849:       
                   11850:       if (rval == GSL_SUCCESS)
                   11851:         printf ("converged to a local maximum at\n");
                   11852:       
                   11853:       printf("%5d ", iteri);
                   11854:       for (it = 0; it < NDIM; it++){
                   11855:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11856:       }
                   11857:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11858:     }
                   11859:     
                   11860:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11861:     
                   11862:     gsl_vector_free(x); /* initial values */
                   11863:     gsl_vector_free(ss); /* inital step size */
                   11864:     for (it=0; it<NDIM; it++){
                   11865:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11866:       fprintf(ficrespow," %.12lf", p[it]);
                   11867:     }
                   11868:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11869: #endif
                   11870: #ifdef POWELL
                   11871:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11872: #endif  
1.126     brouard  11873:     fclose(ficrespow);
                   11874:     
1.203     brouard  11875:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11876: 
                   11877:     for(i=1; i <=NDIM; i++)
                   11878:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11879:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11880:     
                   11881:     printf("\nCovariance matrix\n ");
1.203     brouard  11882:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11883:     for(i=1; i <=NDIM; i++) {
                   11884:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11885:                                printf("%f ",matcov[i][j]);
                   11886:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11887:       }
1.203     brouard  11888:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11889:     }
                   11890:     
                   11891:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11892:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11893:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11894:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11895:     }
1.126     brouard  11896:     lsurv=vector(1,AGESUP);
                   11897:     lpop=vector(1,AGESUP);
                   11898:     tpop=vector(1,AGESUP);
                   11899:     lsurv[agegomp]=100000;
                   11900:     
                   11901:     for (k=agegomp;k<=AGESUP;k++) {
                   11902:       agemortsup=k;
                   11903:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11904:     }
                   11905:     
                   11906:     for (k=agegomp;k<agemortsup;k++)
                   11907:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11908:     
                   11909:     for (k=agegomp;k<agemortsup;k++){
                   11910:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11911:       sumlpop=sumlpop+lpop[k];
                   11912:     }
                   11913:     
                   11914:     tpop[agegomp]=sumlpop;
                   11915:     for (k=agegomp;k<(agemortsup-3);k++){
                   11916:       /*  tpop[k+1]=2;*/
                   11917:       tpop[k+1]=tpop[k]-lpop[k];
                   11918:     }
                   11919:     
                   11920:     
                   11921:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11922:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11923:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11924:     
                   11925:     
                   11926:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11927:                ageminpar=50;
                   11928:                agemaxpar=100;
1.194     brouard  11929:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11930:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11931: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11932: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11933:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11934: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11935: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11936:     }else{
                   11937:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11938:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11939:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11940:                }
1.201     brouard  11941:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11942:                     stepm, weightopt,\
                   11943:                     model,imx,p,matcov,agemortsup);
                   11944:     
                   11945:     free_vector(lsurv,1,AGESUP);
                   11946:     free_vector(lpop,1,AGESUP);
                   11947:     free_vector(tpop,1,AGESUP);
1.220     brouard  11948:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  11949:     free_ivector(dcwave,firstobs,lastobs);
                   11950:     free_vector(agecens,firstobs,lastobs);
                   11951:     free_vector(ageexmed,firstobs,lastobs);
                   11952:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  11953: #ifdef GSL
1.136     brouard  11954: #endif
1.186     brouard  11955:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11956:   /* Standard  */
                   11957:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11958:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11959:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11960:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11961:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11962:     for (k=1; k<=npar;k++)
                   11963:       printf(" %d %8.5f",k,p[k]);
                   11964:     printf("\n");
1.205     brouard  11965:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11966:       /* mlikeli uses func not funcone */
1.247     brouard  11967:       /* for(i=1;i<nlstate;i++){ */
                   11968:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11969:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11970:       /* } */
1.205     brouard  11971:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11972:     }
                   11973:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11974:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11975:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11976:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11977:     }
                   11978:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11979:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11980:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11981:     for (k=1; k<=npar;k++)
                   11982:       printf(" %d %8.5f",k,p[k]);
                   11983:     printf("\n");
                   11984:     
                   11985:     /*--------- results files --------------*/
1.283     brouard  11986:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  11987:     
                   11988:     
                   11989:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11990:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11991:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   11992:     for(i=1,jk=1; i <=nlstate; i++){
                   11993:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  11994:        if (k != i) {
                   11995:          printf("%d%d ",i,k);
                   11996:          fprintf(ficlog,"%d%d ",i,k);
                   11997:          fprintf(ficres,"%1d%1d ",i,k);
                   11998:          for(j=1; j <=ncovmodel; j++){
                   11999:            printf("%12.7f ",p[jk]);
                   12000:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12001:            fprintf(ficres,"%12.7f ",p[jk]);
                   12002:            jk++; 
                   12003:          }
                   12004:          printf("\n");
                   12005:          fprintf(ficlog,"\n");
                   12006:          fprintf(ficres,"\n");
                   12007:        }
1.126     brouard  12008:       }
                   12009:     }
1.203     brouard  12010:     if(mle != 0){
                   12011:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12012:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12013:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12014:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12015:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12016:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12017:        for(k=1; k <=(nlstate+ndeath); k++){
                   12018:          if (k != i) {
                   12019:            printf("%d%d ",i,k);
                   12020:            fprintf(ficlog,"%d%d ",i,k);
                   12021:            for(j=1; j <=ncovmodel; j++){
                   12022:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12023:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12024:              jk++; 
                   12025:            }
                   12026:            printf("\n");
                   12027:            fprintf(ficlog,"\n");
                   12028:          }
                   12029:        }
1.193     brouard  12030:       }
1.203     brouard  12031:     } /* end of hesscov and Wald tests */
1.225     brouard  12032:     
1.203     brouard  12033:     /*  */
1.126     brouard  12034:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12035:     printf("# Scales (for hessian or gradient estimation)\n");
                   12036:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12037:     for(i=1,jk=1; i <=nlstate; i++){
                   12038:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12039:        if (j!=i) {
                   12040:          fprintf(ficres,"%1d%1d",i,j);
                   12041:          printf("%1d%1d",i,j);
                   12042:          fprintf(ficlog,"%1d%1d",i,j);
                   12043:          for(k=1; k<=ncovmodel;k++){
                   12044:            printf(" %.5e",delti[jk]);
                   12045:            fprintf(ficlog," %.5e",delti[jk]);
                   12046:            fprintf(ficres," %.5e",delti[jk]);
                   12047:            jk++;
                   12048:          }
                   12049:          printf("\n");
                   12050:          fprintf(ficlog,"\n");
                   12051:          fprintf(ficres,"\n");
                   12052:        }
1.126     brouard  12053:       }
                   12054:     }
                   12055:     
                   12056:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12057:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12058:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12059:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12060:     /* # 121 Var(a12)\n\ */
                   12061:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12062:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12063:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12064:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12065:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12066:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12067:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12068:     
                   12069:     
                   12070:     /* Just to have a covariance matrix which will be more understandable
                   12071:        even is we still don't want to manage dictionary of variables
                   12072:     */
                   12073:     for(itimes=1;itimes<=2;itimes++){
                   12074:       jj=0;
                   12075:       for(i=1; i <=nlstate; i++){
1.225     brouard  12076:        for(j=1; j <=nlstate+ndeath; j++){
                   12077:          if(j==i) continue;
                   12078:          for(k=1; k<=ncovmodel;k++){
                   12079:            jj++;
                   12080:            ca[0]= k+'a'-1;ca[1]='\0';
                   12081:            if(itimes==1){
                   12082:              if(mle>=1)
                   12083:                printf("#%1d%1d%d",i,j,k);
                   12084:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12085:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12086:            }else{
                   12087:              if(mle>=1)
                   12088:                printf("%1d%1d%d",i,j,k);
                   12089:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12090:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12091:            }
                   12092:            ll=0;
                   12093:            for(li=1;li <=nlstate; li++){
                   12094:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12095:                if(lj==li) continue;
                   12096:                for(lk=1;lk<=ncovmodel;lk++){
                   12097:                  ll++;
                   12098:                  if(ll<=jj){
                   12099:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12100:                    if(ll<jj){
                   12101:                      if(itimes==1){
                   12102:                        if(mle>=1)
                   12103:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12104:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12105:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12106:                      }else{
                   12107:                        if(mle>=1)
                   12108:                          printf(" %.5e",matcov[jj][ll]); 
                   12109:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12110:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12111:                      }
                   12112:                    }else{
                   12113:                      if(itimes==1){
                   12114:                        if(mle>=1)
                   12115:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12116:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12117:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12118:                      }else{
                   12119:                        if(mle>=1)
                   12120:                          printf(" %.7e",matcov[jj][ll]); 
                   12121:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12122:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12123:                      }
                   12124:                    }
                   12125:                  }
                   12126:                } /* end lk */
                   12127:              } /* end lj */
                   12128:            } /* end li */
                   12129:            if(mle>=1)
                   12130:              printf("\n");
                   12131:            fprintf(ficlog,"\n");
                   12132:            fprintf(ficres,"\n");
                   12133:            numlinepar++;
                   12134:          } /* end k*/
                   12135:        } /*end j */
1.126     brouard  12136:       } /* end i */
                   12137:     } /* end itimes */
                   12138:     
                   12139:     fflush(ficlog);
                   12140:     fflush(ficres);
1.225     brouard  12141:     while(fgets(line, MAXLINE, ficpar)) {
                   12142:       /* If line starts with a # it is a comment */
                   12143:       if (line[0] == '#') {
                   12144:        numlinepar++;
                   12145:        fputs(line,stdout);
                   12146:        fputs(line,ficparo);
                   12147:        fputs(line,ficlog);
                   12148:        continue;
                   12149:       }else
                   12150:        break;
                   12151:     }
                   12152:     
1.209     brouard  12153:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12154:     /*   ungetc(c,ficpar); */
                   12155:     /*   fgets(line, MAXLINE, ficpar); */
                   12156:     /*   fputs(line,stdout); */
                   12157:     /*   fputs(line,ficparo); */
                   12158:     /* } */
                   12159:     /* ungetc(c,ficpar); */
1.126     brouard  12160:     
                   12161:     estepm=0;
1.209     brouard  12162:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12163:       
                   12164:       if (num_filled != 6) {
                   12165:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12166:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12167:        goto end;
                   12168:       }
                   12169:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12170:     }
                   12171:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12172:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12173:     
1.209     brouard  12174:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12175:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12176:     if (fage <= 2) {
                   12177:       bage = ageminpar;
                   12178:       fage = agemaxpar;
                   12179:     }
                   12180:     
                   12181:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12182:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12183:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12184:                
1.186     brouard  12185:     /* Other stuffs, more or less useful */    
1.254     brouard  12186:     while(fgets(line, MAXLINE, ficpar)) {
                   12187:       /* If line starts with a # it is a comment */
                   12188:       if (line[0] == '#') {
                   12189:        numlinepar++;
                   12190:        fputs(line,stdout);
                   12191:        fputs(line,ficparo);
                   12192:        fputs(line,ficlog);
                   12193:        continue;
                   12194:       }else
                   12195:        break;
                   12196:     }
                   12197: 
                   12198:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12199:       
                   12200:       if (num_filled != 7) {
                   12201:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12202:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12203:        goto end;
                   12204:       }
                   12205:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12206:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12207:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12208:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12209:     }
1.254     brouard  12210: 
                   12211:     while(fgets(line, MAXLINE, ficpar)) {
                   12212:       /* If line starts with a # it is a comment */
                   12213:       if (line[0] == '#') {
                   12214:        numlinepar++;
                   12215:        fputs(line,stdout);
                   12216:        fputs(line,ficparo);
                   12217:        fputs(line,ficlog);
                   12218:        continue;
                   12219:       }else
                   12220:        break;
1.126     brouard  12221:     }
                   12222:     
                   12223:     
                   12224:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12225:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12226:     
1.254     brouard  12227:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12228:       if (num_filled != 1) {
                   12229:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12230:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12231:        goto end;
                   12232:       }
                   12233:       printf("pop_based=%d\n",popbased);
                   12234:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12235:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12236:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12237:     }
                   12238:      
1.258     brouard  12239:     /* Results */
                   12240:     nresult=0;
                   12241:     do{
                   12242:       if(!fgets(line, MAXLINE, ficpar)){
                   12243:        endishere=1;
                   12244:        parameterline=14;
                   12245:       }else if (line[0] == '#') {
                   12246:        /* If line starts with a # it is a comment */
1.254     brouard  12247:        numlinepar++;
                   12248:        fputs(line,stdout);
                   12249:        fputs(line,ficparo);
                   12250:        fputs(line,ficlog);
                   12251:        continue;
1.258     brouard  12252:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12253:        parameterline=11;
                   12254:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12255:        parameterline=12;
                   12256:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12257:        parameterline=13;
                   12258:       else{
                   12259:        parameterline=14;
1.254     brouard  12260:       }
1.258     brouard  12261:       switch (parameterline){ 
                   12262:       case 11:
                   12263:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12264:          if (num_filled != 8) {
                   12265:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12266:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12267:            goto end;
                   12268:          }
                   12269:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12270:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12271:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12272:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12273:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12274:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12275:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
                   12276: 
1.258     brouard  12277:        }
1.254     brouard  12278:        break;
1.258     brouard  12279:       case 12:
                   12280:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12281:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12282:          if (num_filled != 8) {
1.262     brouard  12283:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12284:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12285:            goto end;
                   12286:          }
                   12287:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12288:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12289:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12290:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12291:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12292:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12293:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.258     brouard  12294:        }
1.230     brouard  12295:        break;
1.258     brouard  12296:       case 13:
                   12297:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12298:          if (num_filled == 0){
                   12299:            resultline[0]='\0';
                   12300:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12301:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12302:            break;
                   12303:          } else if (num_filled != 1){
                   12304:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12305:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12306:          }
                   12307:          nresult++; /* Sum of resultlines */
                   12308:          printf("Result %d: result=%s\n",nresult, resultline);
                   12309:          if(nresult > MAXRESULTLINES){
                   12310:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12311:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12312:            goto end;
                   12313:          }
                   12314:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12315:          fprintf(ficparo,"result: %s\n",resultline);
                   12316:          fprintf(ficres,"result: %s\n",resultline);
                   12317:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12318:          break;
1.258     brouard  12319:        case 14: 
1.259     brouard  12320:          if(ncovmodel >2 && nresult==0 ){
                   12321:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12322:            goto end;
                   12323:          }
1.259     brouard  12324:          break;
1.258     brouard  12325:        default:
                   12326:          nresult=1;
                   12327:          decoderesult(".",nresult ); /* No covariate */
                   12328:        }
                   12329:       } /* End switch parameterline */
                   12330:     }while(endishere==0); /* End do */
1.126     brouard  12331:     
1.230     brouard  12332:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12333:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12334:     
                   12335:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12336:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12337:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12338: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12339: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12340:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12341: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12342: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12343:     }else{
1.270     brouard  12344:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12345:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12346:     }
                   12347:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12348:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.273     brouard  12349:                 jprev1,mprev1,anprev1,dateprev1, dateproj1, dateback1,jprev2,mprev2,anprev2,dateprev2,dateproj2, dateback2);
1.220     brouard  12350:                
1.225     brouard  12351:     /*------------ free_vector  -------------*/
                   12352:     /*  chdir(path); */
1.220     brouard  12353:                
1.215     brouard  12354:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12355:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12356:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12357:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12358:     free_lvector(num,firstobs,lastobs);
                   12359:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12360:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12361:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12362:     fclose(ficparo);
                   12363:     fclose(ficres);
1.220     brouard  12364:                
                   12365:                
1.186     brouard  12366:     /* Other results (useful)*/
1.220     brouard  12367:                
                   12368:                
1.126     brouard  12369:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12370:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12371:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12372:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12373:     fclose(ficrespl);
                   12374: 
                   12375:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12376:     /*#include "hpijx.h"*/
                   12377:     hPijx(p, bage, fage);
1.145     brouard  12378:     fclose(ficrespij);
1.227     brouard  12379:     
1.220     brouard  12380:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12381:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12382:     k=1;
1.126     brouard  12383:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12384:     
1.269     brouard  12385:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12386:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12387:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12388:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12389:        for(k=1;k<=ncovcombmax;k++)
                   12390:          probs[i][j][k]=0.;
1.269     brouard  12391:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12392:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12393:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12394:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12395:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12396:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12397:          for(k=1;k<=ncovcombmax;k++)
                   12398:            mobaverages[i][j][k]=0.;
1.219     brouard  12399:       mobaverage=mobaverages;
                   12400:       if (mobilav!=0) {
1.235     brouard  12401:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12402:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12403:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12404:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12405:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12406:        }
1.269     brouard  12407:       } else if (mobilavproj !=0) {
1.235     brouard  12408:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12409:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12410:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12411:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12412:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12413:        }
1.269     brouard  12414:       }else{
                   12415:        printf("Internal error moving average\n");
                   12416:        fflush(stdout);
                   12417:        exit(1);
1.219     brouard  12418:       }
                   12419:     }/* end if moving average */
1.227     brouard  12420:     
1.126     brouard  12421:     /*---------- Forecasting ------------------*/
                   12422:     if(prevfcast==1){
                   12423:       /*    if(stepm ==1){*/
1.269     brouard  12424:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12425:     }
1.269     brouard  12426: 
                   12427:     /* Backcasting */
1.217     brouard  12428:     if(backcast==1){
1.219     brouard  12429:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12430:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12431:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12432: 
                   12433:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12434: 
                   12435:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12436: 
1.219     brouard  12437:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12438:       fclose(ficresplb);
                   12439: 
1.222     brouard  12440:       hBijx(p, bage, fage, mobaverage);
                   12441:       fclose(ficrespijb);
1.219     brouard  12442: 
1.269     brouard  12443:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12444:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12445:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12446: 
                   12447:       
1.269     brouard  12448:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12449:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12450:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12451:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12452:     }    /* end  Backcasting */
1.268     brouard  12453:  
1.186     brouard  12454:  
                   12455:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12456: 
1.215     brouard  12457:     free_ivector(wav,1,imx);
                   12458:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12459:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12460:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12461:                
                   12462:                
1.127     brouard  12463:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12464:                
1.201     brouard  12465:     strcpy(filerese,"E_");
                   12466:     strcat(filerese,fileresu);
1.126     brouard  12467:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12468:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12469:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12470:     }
1.208     brouard  12471:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12472:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12473: 
                   12474:     pstamp(ficreseij);
1.219     brouard  12475:                
1.235     brouard  12476:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12477:     if (cptcovn < 1){i1=1;}
                   12478:     
                   12479:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12480:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12481:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12482:        continue;
1.219     brouard  12483:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12484:       printf("\n#****** ");
1.225     brouard  12485:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12486:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12487:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12488:       }
                   12489:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12490:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12491:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12492:       }
                   12493:       fprintf(ficreseij,"******\n");
1.235     brouard  12494:       printf("******\n");
1.219     brouard  12495:       
                   12496:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12497:       oldm=oldms;savm=savms;
1.235     brouard  12498:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12499:       
1.219     brouard  12500:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12501:     }
                   12502:     fclose(ficreseij);
1.208     brouard  12503:     printf("done evsij\n");fflush(stdout);
                   12504:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12505: 
1.218     brouard  12506:                
1.227     brouard  12507:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12508:                
1.201     brouard  12509:     strcpy(filerest,"T_");
                   12510:     strcat(filerest,fileresu);
1.127     brouard  12511:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12512:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12513:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12514:     }
1.208     brouard  12515:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12516:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12517:     strcpy(fileresstde,"STDE_");
                   12518:     strcat(fileresstde,fileresu);
1.126     brouard  12519:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12520:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12521:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12522:     }
1.227     brouard  12523:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12524:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12525: 
1.201     brouard  12526:     strcpy(filerescve,"CVE_");
                   12527:     strcat(filerescve,fileresu);
1.126     brouard  12528:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12529:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12530:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12531:     }
1.227     brouard  12532:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12533:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12534: 
1.201     brouard  12535:     strcpy(fileresv,"V_");
                   12536:     strcat(fileresv,fileresu);
1.126     brouard  12537:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12538:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12539:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12540:     }
1.227     brouard  12541:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12542:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12543: 
1.235     brouard  12544:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12545:     if (cptcovn < 1){i1=1;}
                   12546:     
                   12547:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12548:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12549:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12550:        continue;
1.242     brouard  12551:       printf("\n#****** Result for:");
                   12552:       fprintf(ficrest,"\n#****** Result for:");
                   12553:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12554:       for(j=1;j<=cptcoveff;j++){ 
                   12555:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12556:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12557:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12558:       }
1.235     brouard  12559:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12560:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12561:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12562:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12563:       }        
1.208     brouard  12564:       fprintf(ficrest,"******\n");
1.227     brouard  12565:       fprintf(ficlog,"******\n");
                   12566:       printf("******\n");
1.208     brouard  12567:       
                   12568:       fprintf(ficresstdeij,"\n#****** ");
                   12569:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12570:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12571:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12572:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12573:       }
1.235     brouard  12574:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12575:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12576:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12577:       }        
1.208     brouard  12578:       fprintf(ficresstdeij,"******\n");
                   12579:       fprintf(ficrescveij,"******\n");
                   12580:       
                   12581:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12582:       /* pstamp(ficresvij); */
1.225     brouard  12583:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12584:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12585:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12586:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12587:       }        
1.208     brouard  12588:       fprintf(ficresvij,"******\n");
                   12589:       
                   12590:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12591:       oldm=oldms;savm=savms;
1.235     brouard  12592:       printf(" cvevsij ");
                   12593:       fprintf(ficlog, " cvevsij ");
                   12594:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12595:       printf(" end cvevsij \n ");
                   12596:       fprintf(ficlog, " end cvevsij \n ");
                   12597:       
                   12598:       /*
                   12599:        */
                   12600:       /* goto endfree; */
                   12601:       
                   12602:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12603:       pstamp(ficrest);
                   12604:       
1.269     brouard  12605:       epj=vector(1,nlstate+1);
1.208     brouard  12606:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12607:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12608:        cptcod= 0; /* To be deleted */
                   12609:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12610:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12611:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12612:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12613:        if(vpopbased==1)
                   12614:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12615:        else
1.288     brouard  12616:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12617:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12618:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12619:        fprintf(ficrest,"\n");
                   12620:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  12621:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   12622:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12623:        for(age=bage; age <=fage ;age++){
1.235     brouard  12624:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12625:          if (vpopbased==1) {
                   12626:            if(mobilav ==0){
                   12627:              for(i=1; i<=nlstate;i++)
                   12628:                prlim[i][i]=probs[(int)age][i][k];
                   12629:            }else{ /* mobilav */ 
                   12630:              for(i=1; i<=nlstate;i++)
                   12631:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12632:            }
                   12633:          }
1.219     brouard  12634:          
1.227     brouard  12635:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12636:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12637:          /* printf(" age %4.0f ",age); */
                   12638:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12639:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12640:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12641:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12642:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12643:            }
                   12644:            epj[nlstate+1] +=epj[j];
                   12645:          }
                   12646:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12647:          
1.227     brouard  12648:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12649:            for(j=1;j <=nlstate;j++)
                   12650:              vepp += vareij[i][j][(int)age];
                   12651:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12652:          for(j=1;j <=nlstate;j++){
                   12653:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12654:          }
                   12655:          fprintf(ficrest,"\n");
                   12656:        }
1.208     brouard  12657:       } /* End vpopbased */
1.269     brouard  12658:       free_vector(epj,1,nlstate+1);
1.208     brouard  12659:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12660:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12661:       printf("done selection\n");fflush(stdout);
                   12662:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12663:       
1.235     brouard  12664:     } /* End k selection */
1.227     brouard  12665: 
                   12666:     printf("done State-specific expectancies\n");fflush(stdout);
                   12667:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12668: 
1.288     brouard  12669:     /* variance-covariance of forward period prevalence*/
1.269     brouard  12670:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12671: 
1.227     brouard  12672:     
1.290     brouard  12673:     free_vector(weight,firstobs,lastobs);
1.227     brouard  12674:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  12675:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   12676:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   12677:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   12678:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  12679:     free_ivector(tab,1,NCOVMAX);
                   12680:     fclose(ficresstdeij);
                   12681:     fclose(ficrescveij);
                   12682:     fclose(ficresvij);
                   12683:     fclose(ficrest);
                   12684:     fclose(ficpar);
                   12685:     
                   12686:     
1.126     brouard  12687:     /*---------- End : free ----------------*/
1.219     brouard  12688:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12689:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12690:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12691:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12692:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12693:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12694:   /* endfree:*/
                   12695:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12696:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12697:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  12698:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   12699:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   12700:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   12701:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  12702:   free_matrix(matcov,1,npar,1,npar);
                   12703:   free_matrix(hess,1,npar,1,npar);
                   12704:   /*free_vector(delti,1,npar);*/
                   12705:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12706:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12707:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12708:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12709:   
                   12710:   free_ivector(ncodemax,1,NCOVMAX);
                   12711:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12712:   free_ivector(Dummy,-1,NCOVMAX);
                   12713:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12714:   free_ivector(DummyV,1,NCOVMAX);
                   12715:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12716:   free_ivector(Typevar,-1,NCOVMAX);
                   12717:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12718:   free_ivector(TvarsQ,1,NCOVMAX);
                   12719:   free_ivector(TvarsQind,1,NCOVMAX);
                   12720:   free_ivector(TvarsD,1,NCOVMAX);
                   12721:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12722:   free_ivector(TvarFD,1,NCOVMAX);
                   12723:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12724:   free_ivector(TvarF,1,NCOVMAX);
                   12725:   free_ivector(TvarFind,1,NCOVMAX);
                   12726:   free_ivector(TvarV,1,NCOVMAX);
                   12727:   free_ivector(TvarVind,1,NCOVMAX);
                   12728:   free_ivector(TvarA,1,NCOVMAX);
                   12729:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12730:   free_ivector(TvarFQ,1,NCOVMAX);
                   12731:   free_ivector(TvarFQind,1,NCOVMAX);
                   12732:   free_ivector(TvarVD,1,NCOVMAX);
                   12733:   free_ivector(TvarVDind,1,NCOVMAX);
                   12734:   free_ivector(TvarVQ,1,NCOVMAX);
                   12735:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12736:   free_ivector(Tvarsel,1,NCOVMAX);
                   12737:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12738:   free_ivector(Tposprod,1,NCOVMAX);
                   12739:   free_ivector(Tprod,1,NCOVMAX);
                   12740:   free_ivector(Tvaraff,1,NCOVMAX);
                   12741:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12742:   free_ivector(Tage,1,NCOVMAX);
                   12743:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12744:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12745:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12746:   
                   12747:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12748:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12749:   fflush(fichtm);
                   12750:   fflush(ficgp);
                   12751:   
1.227     brouard  12752:   
1.126     brouard  12753:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12754:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12755:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12756:   }else{
                   12757:     printf("End of Imach\n");
                   12758:     fprintf(ficlog,"End of Imach\n");
                   12759:   }
                   12760:   printf("See log file on %s\n",filelog);
                   12761:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12762:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12763:   rend_time = time(NULL);  
                   12764:   end_time = *localtime(&rend_time);
                   12765:   /* tml = *localtime(&end_time.tm_sec); */
                   12766:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12767:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12768:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12769:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12770:   
1.157     brouard  12771:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12772:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12773:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12774:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12775: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12776:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12777:   fclose(fichtm);
                   12778:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12779:   fclose(fichtmcov);
                   12780:   fclose(ficgp);
                   12781:   fclose(ficlog);
                   12782:   /*------ End -----------*/
1.227     brouard  12783:   
1.281     brouard  12784: 
                   12785: /* Executes gnuplot */
1.227     brouard  12786:   
                   12787:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12788: #ifdef WIN32
1.227     brouard  12789:   if (_chdir(pathcd) != 0)
                   12790:     printf("Can't move to directory %s!\n",path);
                   12791:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12792: #else
1.227     brouard  12793:     if(chdir(pathcd) != 0)
                   12794:       printf("Can't move to directory %s!\n", path);
                   12795:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12796: #endif 
1.126     brouard  12797:     printf("Current directory %s!\n",pathcd);
                   12798:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12799:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12800: #ifdef _WIN32
1.126     brouard  12801:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12802: #endif
                   12803:   if(!stat(plotcmd,&info)){
1.158     brouard  12804:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12805:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12806:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12807:     }else
                   12808:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12809: #ifdef __unix
1.126     brouard  12810:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12811:     if(!stat(plotcmd,&info)){
1.158     brouard  12812:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12813:     }else
                   12814:       strcpy(pplotcmd,plotcmd);
                   12815: #endif
                   12816:   }else
                   12817:     strcpy(pplotcmd,plotcmd);
                   12818:   
                   12819:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12820:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.227     brouard  12821:   
1.126     brouard  12822:   if((outcmd=system(plotcmd)) != 0){
1.158     brouard  12823:     printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12824:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12825:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.150     brouard  12826:     if((outcmd=system(plotcmd)) != 0)
1.153     brouard  12827:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.126     brouard  12828:   }
1.158     brouard  12829:   printf(" Successful, please wait...");
1.126     brouard  12830:   while (z[0] != 'q') {
                   12831:     /* chdir(path); */
1.154     brouard  12832:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12833:     scanf("%s",z);
                   12834: /*     if (z[0] == 'c') system("./imach"); */
                   12835:     if (z[0] == 'e') {
1.158     brouard  12836: #ifdef __APPLE__
1.152     brouard  12837:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12838: #elif __linux
                   12839:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12840: #else
1.152     brouard  12841:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12842: #endif
                   12843:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12844:       system(pplotcmd);
1.126     brouard  12845:     }
                   12846:     else if (z[0] == 'g') system(plotcmd);
                   12847:     else if (z[0] == 'q') exit(0);
                   12848:   }
1.227     brouard  12849: end:
1.126     brouard  12850:   while (z[0] != 'q') {
1.195     brouard  12851:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12852:     scanf("%s",z);
                   12853:   }
1.283     brouard  12854:   printf("End\n");
1.282     brouard  12855:   exit(0);
1.126     brouard  12856: }

FreeBSD-CVSweb <freebsd-cvsweb@FreeBSD.org>