Annotation of imach/src/imach.c, revision 1.292

1.292   ! brouard     1: /* $Id: imach.c,v 1.291 2019/05/09 13:44:18 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.292   ! brouard     4:   Revision 1.291  2019/05/09 13:44:18  brouard
        !             5:   Summary: Before ncovmax
        !             6: 
1.291     brouard     7:   Revision 1.290  2019/05/09 13:39:37  brouard
                      8:   Summary: 0.99r18 unlimited number of individuals
                      9: 
                     10:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                     11: 
1.290     brouard    12:   Revision 1.289  2018/12/13 09:16:26  brouard
                     13:   Summary: Bug for young ages (<-30) will be in r17
                     14: 
1.289     brouard    15:   Revision 1.288  2018/05/02 20:58:27  brouard
                     16:   Summary: Some bugs fixed
                     17: 
1.288     brouard    18:   Revision 1.287  2018/05/01 17:57:25  brouard
                     19:   Summary: Bug fixed by providing frequencies only for non missing covariates
                     20: 
1.287     brouard    21:   Revision 1.286  2018/04/27 14:27:04  brouard
                     22:   Summary: some minor bugs
                     23: 
1.286     brouard    24:   Revision 1.285  2018/04/21 21:02:16  brouard
                     25:   Summary: Some bugs fixed, valgrind tested
                     26: 
1.285     brouard    27:   Revision 1.284  2018/04/20 05:22:13  brouard
                     28:   Summary: Computing mean and stdeviation of fixed quantitative variables
                     29: 
1.284     brouard    30:   Revision 1.283  2018/04/19 14:49:16  brouard
                     31:   Summary: Some minor bugs fixed
                     32: 
1.283     brouard    33:   Revision 1.282  2018/02/27 22:50:02  brouard
                     34:   *** empty log message ***
                     35: 
1.282     brouard    36:   Revision 1.281  2018/02/27 19:25:23  brouard
                     37:   Summary: Adding second argument for quitting
                     38: 
1.281     brouard    39:   Revision 1.280  2018/02/21 07:58:13  brouard
                     40:   Summary: 0.99r15
                     41: 
                     42:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                     43: 
1.280     brouard    44:   Revision 1.279  2017/07/20 13:35:01  brouard
                     45:   Summary: temporary working
                     46: 
1.279     brouard    47:   Revision 1.278  2017/07/19 14:09:02  brouard
                     48:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                     49: 
1.278     brouard    50:   Revision 1.277  2017/07/17 08:53:49  brouard
                     51:   Summary: BOM files can be read now
                     52: 
1.277     brouard    53:   Revision 1.276  2017/06/30 15:48:31  brouard
                     54:   Summary: Graphs improvements
                     55: 
1.276     brouard    56:   Revision 1.275  2017/06/30 13:39:33  brouard
                     57:   Summary: Saito's color
                     58: 
1.275     brouard    59:   Revision 1.274  2017/06/29 09:47:08  brouard
                     60:   Summary: Version 0.99r14
                     61: 
1.274     brouard    62:   Revision 1.273  2017/06/27 11:06:02  brouard
                     63:   Summary: More documentation on projections
                     64: 
1.273     brouard    65:   Revision 1.272  2017/06/27 10:22:40  brouard
                     66:   Summary: Color of backprojection changed from 6 to 5(yellow)
                     67: 
1.272     brouard    68:   Revision 1.271  2017/06/27 10:17:50  brouard
                     69:   Summary: Some bug with rint
                     70: 
1.271     brouard    71:   Revision 1.270  2017/05/24 05:45:29  brouard
                     72:   *** empty log message ***
                     73: 
1.270     brouard    74:   Revision 1.269  2017/05/23 08:39:25  brouard
                     75:   Summary: Code into subroutine, cleanings
                     76: 
1.269     brouard    77:   Revision 1.268  2017/05/18 20:09:32  brouard
                     78:   Summary: backprojection and confidence intervals of backprevalence
                     79: 
1.268     brouard    80:   Revision 1.267  2017/05/13 10:25:05  brouard
                     81:   Summary: temporary save for backprojection
                     82: 
1.267     brouard    83:   Revision 1.266  2017/05/13 07:26:12  brouard
                     84:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     85: 
1.266     brouard    86:   Revision 1.265  2017/04/26 16:22:11  brouard
                     87:   Summary: imach 0.99r13 Some bugs fixed
                     88: 
1.265     brouard    89:   Revision 1.264  2017/04/26 06:01:29  brouard
                     90:   Summary: Labels in graphs
                     91: 
1.264     brouard    92:   Revision 1.263  2017/04/24 15:23:15  brouard
                     93:   Summary: to save
                     94: 
1.263     brouard    95:   Revision 1.262  2017/04/18 16:48:12  brouard
                     96:   *** empty log message ***
                     97: 
1.262     brouard    98:   Revision 1.261  2017/04/05 10:14:09  brouard
                     99:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    100: 
1.261     brouard   101:   Revision 1.260  2017/04/04 17:46:59  brouard
                    102:   Summary: Gnuplot indexations fixed (humm)
                    103: 
1.260     brouard   104:   Revision 1.259  2017/04/04 13:01:16  brouard
                    105:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    106: 
1.259     brouard   107:   Revision 1.258  2017/04/03 10:17:47  brouard
                    108:   Summary: Version 0.99r12
                    109: 
                    110:   Some cleanings, conformed with updated documentation.
                    111: 
1.258     brouard   112:   Revision 1.257  2017/03/29 16:53:30  brouard
                    113:   Summary: Temp
                    114: 
1.257     brouard   115:   Revision 1.256  2017/03/27 05:50:23  brouard
                    116:   Summary: Temporary
                    117: 
1.256     brouard   118:   Revision 1.255  2017/03/08 16:02:28  brouard
                    119:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    120: 
1.255     brouard   121:   Revision 1.254  2017/03/08 07:13:00  brouard
                    122:   Summary: Fixing data parameter line
                    123: 
1.254     brouard   124:   Revision 1.253  2016/12/15 11:59:41  brouard
                    125:   Summary: 0.99 in progress
                    126: 
1.253     brouard   127:   Revision 1.252  2016/09/15 21:15:37  brouard
                    128:   *** empty log message ***
                    129: 
1.252     brouard   130:   Revision 1.251  2016/09/15 15:01:13  brouard
                    131:   Summary: not working
                    132: 
1.251     brouard   133:   Revision 1.250  2016/09/08 16:07:27  brouard
                    134:   Summary: continue
                    135: 
1.250     brouard   136:   Revision 1.249  2016/09/07 17:14:18  brouard
                    137:   Summary: Starting values from frequencies
                    138: 
1.249     brouard   139:   Revision 1.248  2016/09/07 14:10:18  brouard
                    140:   *** empty log message ***
                    141: 
1.248     brouard   142:   Revision 1.247  2016/09/02 11:11:21  brouard
                    143:   *** empty log message ***
                    144: 
1.247     brouard   145:   Revision 1.246  2016/09/02 08:49:22  brouard
                    146:   *** empty log message ***
                    147: 
1.246     brouard   148:   Revision 1.245  2016/09/02 07:25:01  brouard
                    149:   *** empty log message ***
                    150: 
1.245     brouard   151:   Revision 1.244  2016/09/02 07:17:34  brouard
                    152:   *** empty log message ***
                    153: 
1.244     brouard   154:   Revision 1.243  2016/09/02 06:45:35  brouard
                    155:   *** empty log message ***
                    156: 
1.243     brouard   157:   Revision 1.242  2016/08/30 15:01:20  brouard
                    158:   Summary: Fixing a lots
                    159: 
1.242     brouard   160:   Revision 1.241  2016/08/29 17:17:25  brouard
                    161:   Summary: gnuplot problem in Back projection to fix
                    162: 
1.241     brouard   163:   Revision 1.240  2016/08/29 07:53:18  brouard
                    164:   Summary: Better
                    165: 
1.240     brouard   166:   Revision 1.239  2016/08/26 15:51:03  brouard
                    167:   Summary: Improvement in Powell output in order to copy and paste
                    168: 
                    169:   Author:
                    170: 
1.239     brouard   171:   Revision 1.238  2016/08/26 14:23:35  brouard
                    172:   Summary: Starting tests of 0.99
                    173: 
1.238     brouard   174:   Revision 1.237  2016/08/26 09:20:19  brouard
                    175:   Summary: to valgrind
                    176: 
1.237     brouard   177:   Revision 1.236  2016/08/25 10:50:18  brouard
                    178:   *** empty log message ***
                    179: 
1.236     brouard   180:   Revision 1.235  2016/08/25 06:59:23  brouard
                    181:   *** empty log message ***
                    182: 
1.235     brouard   183:   Revision 1.234  2016/08/23 16:51:20  brouard
                    184:   *** empty log message ***
                    185: 
1.234     brouard   186:   Revision 1.233  2016/08/23 07:40:50  brouard
                    187:   Summary: not working
                    188: 
1.233     brouard   189:   Revision 1.232  2016/08/22 14:20:21  brouard
                    190:   Summary: not working
                    191: 
1.232     brouard   192:   Revision 1.231  2016/08/22 07:17:15  brouard
                    193:   Summary: not working
                    194: 
1.231     brouard   195:   Revision 1.230  2016/08/22 06:55:53  brouard
                    196:   Summary: Not working
                    197: 
1.230     brouard   198:   Revision 1.229  2016/07/23 09:45:53  brouard
                    199:   Summary: Completing for func too
                    200: 
1.229     brouard   201:   Revision 1.228  2016/07/22 17:45:30  brouard
                    202:   Summary: Fixing some arrays, still debugging
                    203: 
1.227     brouard   204:   Revision 1.226  2016/07/12 18:42:34  brouard
                    205:   Summary: temp
                    206: 
1.226     brouard   207:   Revision 1.225  2016/07/12 08:40:03  brouard
                    208:   Summary: saving but not running
                    209: 
1.225     brouard   210:   Revision 1.224  2016/07/01 13:16:01  brouard
                    211:   Summary: Fixes
                    212: 
1.224     brouard   213:   Revision 1.223  2016/02/19 09:23:35  brouard
                    214:   Summary: temporary
                    215: 
1.223     brouard   216:   Revision 1.222  2016/02/17 08:14:50  brouard
                    217:   Summary: Probably last 0.98 stable version 0.98r6
                    218: 
1.222     brouard   219:   Revision 1.221  2016/02/15 23:35:36  brouard
                    220:   Summary: minor bug
                    221: 
1.220     brouard   222:   Revision 1.219  2016/02/15 00:48:12  brouard
                    223:   *** empty log message ***
                    224: 
1.219     brouard   225:   Revision 1.218  2016/02/12 11:29:23  brouard
                    226:   Summary: 0.99 Back projections
                    227: 
1.218     brouard   228:   Revision 1.217  2015/12/23 17:18:31  brouard
                    229:   Summary: Experimental backcast
                    230: 
1.217     brouard   231:   Revision 1.216  2015/12/18 17:32:11  brouard
                    232:   Summary: 0.98r4 Warning and status=-2
                    233: 
                    234:   Version 0.98r4 is now:
                    235:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    236:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    237:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    238: 
1.216     brouard   239:   Revision 1.215  2015/12/16 08:52:24  brouard
                    240:   Summary: 0.98r4 working
                    241: 
1.215     brouard   242:   Revision 1.214  2015/12/16 06:57:54  brouard
                    243:   Summary: temporary not working
                    244: 
1.214     brouard   245:   Revision 1.213  2015/12/11 18:22:17  brouard
                    246:   Summary: 0.98r4
                    247: 
1.213     brouard   248:   Revision 1.212  2015/11/21 12:47:24  brouard
                    249:   Summary: minor typo
                    250: 
1.212     brouard   251:   Revision 1.211  2015/11/21 12:41:11  brouard
                    252:   Summary: 0.98r3 with some graph of projected cross-sectional
                    253: 
                    254:   Author: Nicolas Brouard
                    255: 
1.211     brouard   256:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   257:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   258:   Summary: Adding ftolpl parameter
                    259:   Author: N Brouard
                    260: 
                    261:   We had difficulties to get smoothed confidence intervals. It was due
                    262:   to the period prevalence which wasn't computed accurately. The inner
                    263:   parameter ftolpl is now an outer parameter of the .imach parameter
                    264:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    265:   computation are long.
                    266: 
1.209     brouard   267:   Revision 1.208  2015/11/17 14:31:57  brouard
                    268:   Summary: temporary
                    269: 
1.208     brouard   270:   Revision 1.207  2015/10/27 17:36:57  brouard
                    271:   *** empty log message ***
                    272: 
1.207     brouard   273:   Revision 1.206  2015/10/24 07:14:11  brouard
                    274:   *** empty log message ***
                    275: 
1.206     brouard   276:   Revision 1.205  2015/10/23 15:50:53  brouard
                    277:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    278: 
1.205     brouard   279:   Revision 1.204  2015/10/01 16:20:26  brouard
                    280:   Summary: Some new graphs of contribution to likelihood
                    281: 
1.204     brouard   282:   Revision 1.203  2015/09/30 17:45:14  brouard
                    283:   Summary: looking at better estimation of the hessian
                    284: 
                    285:   Also a better criteria for convergence to the period prevalence And
                    286:   therefore adding the number of years needed to converge. (The
                    287:   prevalence in any alive state shold sum to one
                    288: 
1.203     brouard   289:   Revision 1.202  2015/09/22 19:45:16  brouard
                    290:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    291: 
1.202     brouard   292:   Revision 1.201  2015/09/15 17:34:58  brouard
                    293:   Summary: 0.98r0
                    294: 
                    295:   - Some new graphs like suvival functions
                    296:   - Some bugs fixed like model=1+age+V2.
                    297: 
1.201     brouard   298:   Revision 1.200  2015/09/09 16:53:55  brouard
                    299:   Summary: Big bug thanks to Flavia
                    300: 
                    301:   Even model=1+age+V2. did not work anymore
                    302: 
1.200     brouard   303:   Revision 1.199  2015/09/07 14:09:23  brouard
                    304:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    305: 
1.199     brouard   306:   Revision 1.198  2015/09/03 07:14:39  brouard
                    307:   Summary: 0.98q5 Flavia
                    308: 
1.198     brouard   309:   Revision 1.197  2015/09/01 18:24:39  brouard
                    310:   *** empty log message ***
                    311: 
1.197     brouard   312:   Revision 1.196  2015/08/18 23:17:52  brouard
                    313:   Summary: 0.98q5
                    314: 
1.196     brouard   315:   Revision 1.195  2015/08/18 16:28:39  brouard
                    316:   Summary: Adding a hack for testing purpose
                    317: 
                    318:   After reading the title, ftol and model lines, if the comment line has
                    319:   a q, starting with #q, the answer at the end of the run is quit. It
                    320:   permits to run test files in batch with ctest. The former workaround was
                    321:   $ echo q | imach foo.imach
                    322: 
1.195     brouard   323:   Revision 1.194  2015/08/18 13:32:00  brouard
                    324:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    325: 
1.194     brouard   326:   Revision 1.193  2015/08/04 07:17:42  brouard
                    327:   Summary: 0.98q4
                    328: 
1.193     brouard   329:   Revision 1.192  2015/07/16 16:49:02  brouard
                    330:   Summary: Fixing some outputs
                    331: 
1.192     brouard   332:   Revision 1.191  2015/07/14 10:00:33  brouard
                    333:   Summary: Some fixes
                    334: 
1.191     brouard   335:   Revision 1.190  2015/05/05 08:51:13  brouard
                    336:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    337: 
                    338:   Fix 1+age+.
                    339: 
1.190     brouard   340:   Revision 1.189  2015/04/30 14:45:16  brouard
                    341:   Summary: 0.98q2
                    342: 
1.189     brouard   343:   Revision 1.188  2015/04/30 08:27:53  brouard
                    344:   *** empty log message ***
                    345: 
1.188     brouard   346:   Revision 1.187  2015/04/29 09:11:15  brouard
                    347:   *** empty log message ***
                    348: 
1.187     brouard   349:   Revision 1.186  2015/04/23 12:01:52  brouard
                    350:   Summary: V1*age is working now, version 0.98q1
                    351: 
                    352:   Some codes had been disabled in order to simplify and Vn*age was
                    353:   working in the optimization phase, ie, giving correct MLE parameters,
                    354:   but, as usual, outputs were not correct and program core dumped.
                    355: 
1.186     brouard   356:   Revision 1.185  2015/03/11 13:26:42  brouard
                    357:   Summary: Inclusion of compile and links command line for Intel Compiler
                    358: 
1.185     brouard   359:   Revision 1.184  2015/03/11 11:52:39  brouard
                    360:   Summary: Back from Windows 8. Intel Compiler
                    361: 
1.184     brouard   362:   Revision 1.183  2015/03/10 20:34:32  brouard
                    363:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    364: 
                    365:   We use directest instead of original Powell test; probably no
                    366:   incidence on the results, but better justifications;
                    367:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    368:   wrong results.
                    369: 
1.183     brouard   370:   Revision 1.182  2015/02/12 08:19:57  brouard
                    371:   Summary: Trying to keep directest which seems simpler and more general
                    372:   Author: Nicolas Brouard
                    373: 
1.182     brouard   374:   Revision 1.181  2015/02/11 23:22:24  brouard
                    375:   Summary: Comments on Powell added
                    376: 
                    377:   Author:
                    378: 
1.181     brouard   379:   Revision 1.180  2015/02/11 17:33:45  brouard
                    380:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    381: 
1.180     brouard   382:   Revision 1.179  2015/01/04 09:57:06  brouard
                    383:   Summary: back to OS/X
                    384: 
1.179     brouard   385:   Revision 1.178  2015/01/04 09:35:48  brouard
                    386:   *** empty log message ***
                    387: 
1.178     brouard   388:   Revision 1.177  2015/01/03 18:40:56  brouard
                    389:   Summary: Still testing ilc32 on OSX
                    390: 
1.177     brouard   391:   Revision 1.176  2015/01/03 16:45:04  brouard
                    392:   *** empty log message ***
                    393: 
1.176     brouard   394:   Revision 1.175  2015/01/03 16:33:42  brouard
                    395:   *** empty log message ***
                    396: 
1.175     brouard   397:   Revision 1.174  2015/01/03 16:15:49  brouard
                    398:   Summary: Still in cross-compilation
                    399: 
1.174     brouard   400:   Revision 1.173  2015/01/03 12:06:26  brouard
                    401:   Summary: trying to detect cross-compilation
                    402: 
1.173     brouard   403:   Revision 1.172  2014/12/27 12:07:47  brouard
                    404:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    405: 
1.172     brouard   406:   Revision 1.171  2014/12/23 13:26:59  brouard
                    407:   Summary: Back from Visual C
                    408: 
                    409:   Still problem with utsname.h on Windows
                    410: 
1.171     brouard   411:   Revision 1.170  2014/12/23 11:17:12  brouard
                    412:   Summary: Cleaning some \%% back to %%
                    413: 
                    414:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    415: 
1.170     brouard   416:   Revision 1.169  2014/12/22 23:08:31  brouard
                    417:   Summary: 0.98p
                    418: 
                    419:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    420: 
1.169     brouard   421:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   422:   Summary: update
1.169     brouard   423: 
1.168     brouard   424:   Revision 1.167  2014/12/22 13:50:56  brouard
                    425:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    426: 
                    427:   Testing on Linux 64
                    428: 
1.167     brouard   429:   Revision 1.166  2014/12/22 11:40:47  brouard
                    430:   *** empty log message ***
                    431: 
1.166     brouard   432:   Revision 1.165  2014/12/16 11:20:36  brouard
                    433:   Summary: After compiling on Visual C
                    434: 
                    435:   * imach.c (Module): Merging 1.61 to 1.162
                    436: 
1.165     brouard   437:   Revision 1.164  2014/12/16 10:52:11  brouard
                    438:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    439: 
                    440:   * imach.c (Module): Merging 1.61 to 1.162
                    441: 
1.164     brouard   442:   Revision 1.163  2014/12/16 10:30:11  brouard
                    443:   * imach.c (Module): Merging 1.61 to 1.162
                    444: 
1.163     brouard   445:   Revision 1.162  2014/09/25 11:43:39  brouard
                    446:   Summary: temporary backup 0.99!
                    447: 
1.162     brouard   448:   Revision 1.1  2014/09/16 11:06:58  brouard
                    449:   Summary: With some code (wrong) for nlopt
                    450: 
                    451:   Author:
                    452: 
                    453:   Revision 1.161  2014/09/15 20:41:41  brouard
                    454:   Summary: Problem with macro SQR on Intel compiler
                    455: 
1.161     brouard   456:   Revision 1.160  2014/09/02 09:24:05  brouard
                    457:   *** empty log message ***
                    458: 
1.160     brouard   459:   Revision 1.159  2014/09/01 10:34:10  brouard
                    460:   Summary: WIN32
                    461:   Author: Brouard
                    462: 
1.159     brouard   463:   Revision 1.158  2014/08/27 17:11:51  brouard
                    464:   *** empty log message ***
                    465: 
1.158     brouard   466:   Revision 1.157  2014/08/27 16:26:55  brouard
                    467:   Summary: Preparing windows Visual studio version
                    468:   Author: Brouard
                    469: 
                    470:   In order to compile on Visual studio, time.h is now correct and time_t
                    471:   and tm struct should be used. difftime should be used but sometimes I
                    472:   just make the differences in raw time format (time(&now).
                    473:   Trying to suppress #ifdef LINUX
                    474:   Add xdg-open for __linux in order to open default browser.
                    475: 
1.157     brouard   476:   Revision 1.156  2014/08/25 20:10:10  brouard
                    477:   *** empty log message ***
                    478: 
1.156     brouard   479:   Revision 1.155  2014/08/25 18:32:34  brouard
                    480:   Summary: New compile, minor changes
                    481:   Author: Brouard
                    482: 
1.155     brouard   483:   Revision 1.154  2014/06/20 17:32:08  brouard
                    484:   Summary: Outputs now all graphs of convergence to period prevalence
                    485: 
1.154     brouard   486:   Revision 1.153  2014/06/20 16:45:46  brouard
                    487:   Summary: If 3 live state, convergence to period prevalence on same graph
                    488:   Author: Brouard
                    489: 
1.153     brouard   490:   Revision 1.152  2014/06/18 17:54:09  brouard
                    491:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    492: 
1.152     brouard   493:   Revision 1.151  2014/06/18 16:43:30  brouard
                    494:   *** empty log message ***
                    495: 
1.151     brouard   496:   Revision 1.150  2014/06/18 16:42:35  brouard
                    497:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    498:   Author: brouard
                    499: 
1.150     brouard   500:   Revision 1.149  2014/06/18 15:51:14  brouard
                    501:   Summary: Some fixes in parameter files errors
                    502:   Author: Nicolas Brouard
                    503: 
1.149     brouard   504:   Revision 1.148  2014/06/17 17:38:48  brouard
                    505:   Summary: Nothing new
                    506:   Author: Brouard
                    507: 
                    508:   Just a new packaging for OS/X version 0.98nS
                    509: 
1.148     brouard   510:   Revision 1.147  2014/06/16 10:33:11  brouard
                    511:   *** empty log message ***
                    512: 
1.147     brouard   513:   Revision 1.146  2014/06/16 10:20:28  brouard
                    514:   Summary: Merge
                    515:   Author: Brouard
                    516: 
                    517:   Merge, before building revised version.
                    518: 
1.146     brouard   519:   Revision 1.145  2014/06/10 21:23:15  brouard
                    520:   Summary: Debugging with valgrind
                    521:   Author: Nicolas Brouard
                    522: 
                    523:   Lot of changes in order to output the results with some covariates
                    524:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    525:   improve the code.
                    526:   No more memory valgrind error but a lot has to be done in order to
                    527:   continue the work of splitting the code into subroutines.
                    528:   Also, decodemodel has been improved. Tricode is still not
                    529:   optimal. nbcode should be improved. Documentation has been added in
                    530:   the source code.
                    531: 
1.144     brouard   532:   Revision 1.143  2014/01/26 09:45:38  brouard
                    533:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    534: 
                    535:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    536:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    537: 
1.143     brouard   538:   Revision 1.142  2014/01/26 03:57:36  brouard
                    539:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    540: 
                    541:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    542: 
1.142     brouard   543:   Revision 1.141  2014/01/26 02:42:01  brouard
                    544:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    545: 
1.141     brouard   546:   Revision 1.140  2011/09/02 10:37:54  brouard
                    547:   Summary: times.h is ok with mingw32 now.
                    548: 
1.140     brouard   549:   Revision 1.139  2010/06/14 07:50:17  brouard
                    550:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    551:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    552: 
1.139     brouard   553:   Revision 1.138  2010/04/30 18:19:40  brouard
                    554:   *** empty log message ***
                    555: 
1.138     brouard   556:   Revision 1.137  2010/04/29 18:11:38  brouard
                    557:   (Module): Checking covariates for more complex models
                    558:   than V1+V2. A lot of change to be done. Unstable.
                    559: 
1.137     brouard   560:   Revision 1.136  2010/04/26 20:30:53  brouard
                    561:   (Module): merging some libgsl code. Fixing computation
                    562:   of likelione (using inter/intrapolation if mle = 0) in order to
                    563:   get same likelihood as if mle=1.
                    564:   Some cleaning of code and comments added.
                    565: 
1.136     brouard   566:   Revision 1.135  2009/10/29 15:33:14  brouard
                    567:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    568: 
1.135     brouard   569:   Revision 1.134  2009/10/29 13:18:53  brouard
                    570:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    571: 
1.134     brouard   572:   Revision 1.133  2009/07/06 10:21:25  brouard
                    573:   just nforces
                    574: 
1.133     brouard   575:   Revision 1.132  2009/07/06 08:22:05  brouard
                    576:   Many tings
                    577: 
1.132     brouard   578:   Revision 1.131  2009/06/20 16:22:47  brouard
                    579:   Some dimensions resccaled
                    580: 
1.131     brouard   581:   Revision 1.130  2009/05/26 06:44:34  brouard
                    582:   (Module): Max Covariate is now set to 20 instead of 8. A
                    583:   lot of cleaning with variables initialized to 0. Trying to make
                    584:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    585: 
1.130     brouard   586:   Revision 1.129  2007/08/31 13:49:27  lievre
                    587:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    588: 
1.129     lievre    589:   Revision 1.128  2006/06/30 13:02:05  brouard
                    590:   (Module): Clarifications on computing e.j
                    591: 
1.128     brouard   592:   Revision 1.127  2006/04/28 18:11:50  brouard
                    593:   (Module): Yes the sum of survivors was wrong since
                    594:   imach-114 because nhstepm was no more computed in the age
                    595:   loop. Now we define nhstepma in the age loop.
                    596:   (Module): In order to speed up (in case of numerous covariates) we
                    597:   compute health expectancies (without variances) in a first step
                    598:   and then all the health expectancies with variances or standard
                    599:   deviation (needs data from the Hessian matrices) which slows the
                    600:   computation.
                    601:   In the future we should be able to stop the program is only health
                    602:   expectancies and graph are needed without standard deviations.
                    603: 
1.127     brouard   604:   Revision 1.126  2006/04/28 17:23:28  brouard
                    605:   (Module): Yes the sum of survivors was wrong since
                    606:   imach-114 because nhstepm was no more computed in the age
                    607:   loop. Now we define nhstepma in the age loop.
                    608:   Version 0.98h
                    609: 
1.126     brouard   610:   Revision 1.125  2006/04/04 15:20:31  lievre
                    611:   Errors in calculation of health expectancies. Age was not initialized.
                    612:   Forecasting file added.
                    613: 
                    614:   Revision 1.124  2006/03/22 17:13:53  lievre
                    615:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    616:   The log-likelihood is printed in the log file
                    617: 
                    618:   Revision 1.123  2006/03/20 10:52:43  brouard
                    619:   * imach.c (Module): <title> changed, corresponds to .htm file
                    620:   name. <head> headers where missing.
                    621: 
                    622:   * imach.c (Module): Weights can have a decimal point as for
                    623:   English (a comma might work with a correct LC_NUMERIC environment,
                    624:   otherwise the weight is truncated).
                    625:   Modification of warning when the covariates values are not 0 or
                    626:   1.
                    627:   Version 0.98g
                    628: 
                    629:   Revision 1.122  2006/03/20 09:45:41  brouard
                    630:   (Module): Weights can have a decimal point as for
                    631:   English (a comma might work with a correct LC_NUMERIC environment,
                    632:   otherwise the weight is truncated).
                    633:   Modification of warning when the covariates values are not 0 or
                    634:   1.
                    635:   Version 0.98g
                    636: 
                    637:   Revision 1.121  2006/03/16 17:45:01  lievre
                    638:   * imach.c (Module): Comments concerning covariates added
                    639: 
                    640:   * imach.c (Module): refinements in the computation of lli if
                    641:   status=-2 in order to have more reliable computation if stepm is
                    642:   not 1 month. Version 0.98f
                    643: 
                    644:   Revision 1.120  2006/03/16 15:10:38  lievre
                    645:   (Module): refinements in the computation of lli if
                    646:   status=-2 in order to have more reliable computation if stepm is
                    647:   not 1 month. Version 0.98f
                    648: 
                    649:   Revision 1.119  2006/03/15 17:42:26  brouard
                    650:   (Module): Bug if status = -2, the loglikelihood was
                    651:   computed as likelihood omitting the logarithm. Version O.98e
                    652: 
                    653:   Revision 1.118  2006/03/14 18:20:07  brouard
                    654:   (Module): varevsij Comments added explaining the second
                    655:   table of variances if popbased=1 .
                    656:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    657:   (Module): Function pstamp added
                    658:   (Module): Version 0.98d
                    659: 
                    660:   Revision 1.117  2006/03/14 17:16:22  brouard
                    661:   (Module): varevsij Comments added explaining the second
                    662:   table of variances if popbased=1 .
                    663:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    664:   (Module): Function pstamp added
                    665:   (Module): Version 0.98d
                    666: 
                    667:   Revision 1.116  2006/03/06 10:29:27  brouard
                    668:   (Module): Variance-covariance wrong links and
                    669:   varian-covariance of ej. is needed (Saito).
                    670: 
                    671:   Revision 1.115  2006/02/27 12:17:45  brouard
                    672:   (Module): One freematrix added in mlikeli! 0.98c
                    673: 
                    674:   Revision 1.114  2006/02/26 12:57:58  brouard
                    675:   (Module): Some improvements in processing parameter
                    676:   filename with strsep.
                    677: 
                    678:   Revision 1.113  2006/02/24 14:20:24  brouard
                    679:   (Module): Memory leaks checks with valgrind and:
                    680:   datafile was not closed, some imatrix were not freed and on matrix
                    681:   allocation too.
                    682: 
                    683:   Revision 1.112  2006/01/30 09:55:26  brouard
                    684:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    685: 
                    686:   Revision 1.111  2006/01/25 20:38:18  brouard
                    687:   (Module): Lots of cleaning and bugs added (Gompertz)
                    688:   (Module): Comments can be added in data file. Missing date values
                    689:   can be a simple dot '.'.
                    690: 
                    691:   Revision 1.110  2006/01/25 00:51:50  brouard
                    692:   (Module): Lots of cleaning and bugs added (Gompertz)
                    693: 
                    694:   Revision 1.109  2006/01/24 19:37:15  brouard
                    695:   (Module): Comments (lines starting with a #) are allowed in data.
                    696: 
                    697:   Revision 1.108  2006/01/19 18:05:42  lievre
                    698:   Gnuplot problem appeared...
                    699:   To be fixed
                    700: 
                    701:   Revision 1.107  2006/01/19 16:20:37  brouard
                    702:   Test existence of gnuplot in imach path
                    703: 
                    704:   Revision 1.106  2006/01/19 13:24:36  brouard
                    705:   Some cleaning and links added in html output
                    706: 
                    707:   Revision 1.105  2006/01/05 20:23:19  lievre
                    708:   *** empty log message ***
                    709: 
                    710:   Revision 1.104  2005/09/30 16:11:43  lievre
                    711:   (Module): sump fixed, loop imx fixed, and simplifications.
                    712:   (Module): If the status is missing at the last wave but we know
                    713:   that the person is alive, then we can code his/her status as -2
                    714:   (instead of missing=-1 in earlier versions) and his/her
                    715:   contributions to the likelihood is 1 - Prob of dying from last
                    716:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    717:   the healthy state at last known wave). Version is 0.98
                    718: 
                    719:   Revision 1.103  2005/09/30 15:54:49  lievre
                    720:   (Module): sump fixed, loop imx fixed, and simplifications.
                    721: 
                    722:   Revision 1.102  2004/09/15 17:31:30  brouard
                    723:   Add the possibility to read data file including tab characters.
                    724: 
                    725:   Revision 1.101  2004/09/15 10:38:38  brouard
                    726:   Fix on curr_time
                    727: 
                    728:   Revision 1.100  2004/07/12 18:29:06  brouard
                    729:   Add version for Mac OS X. Just define UNIX in Makefile
                    730: 
                    731:   Revision 1.99  2004/06/05 08:57:40  brouard
                    732:   *** empty log message ***
                    733: 
                    734:   Revision 1.98  2004/05/16 15:05:56  brouard
                    735:   New version 0.97 . First attempt to estimate force of mortality
                    736:   directly from the data i.e. without the need of knowing the health
                    737:   state at each age, but using a Gompertz model: log u =a + b*age .
                    738:   This is the basic analysis of mortality and should be done before any
                    739:   other analysis, in order to test if the mortality estimated from the
                    740:   cross-longitudinal survey is different from the mortality estimated
                    741:   from other sources like vital statistic data.
                    742: 
                    743:   The same imach parameter file can be used but the option for mle should be -3.
                    744: 
1.133     brouard   745:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   746:   former routines in order to include the new code within the former code.
                    747: 
                    748:   The output is very simple: only an estimate of the intercept and of
                    749:   the slope with 95% confident intervals.
                    750: 
                    751:   Current limitations:
                    752:   A) Even if you enter covariates, i.e. with the
                    753:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    754:   B) There is no computation of Life Expectancy nor Life Table.
                    755: 
                    756:   Revision 1.97  2004/02/20 13:25:42  lievre
                    757:   Version 0.96d. Population forecasting command line is (temporarily)
                    758:   suppressed.
                    759: 
                    760:   Revision 1.96  2003/07/15 15:38:55  brouard
                    761:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    762:   rewritten within the same printf. Workaround: many printfs.
                    763: 
                    764:   Revision 1.95  2003/07/08 07:54:34  brouard
                    765:   * imach.c (Repository):
                    766:   (Repository): Using imachwizard code to output a more meaningful covariance
                    767:   matrix (cov(a12,c31) instead of numbers.
                    768: 
                    769:   Revision 1.94  2003/06/27 13:00:02  brouard
                    770:   Just cleaning
                    771: 
                    772:   Revision 1.93  2003/06/25 16:33:55  brouard
                    773:   (Module): On windows (cygwin) function asctime_r doesn't
                    774:   exist so I changed back to asctime which exists.
                    775:   (Module): Version 0.96b
                    776: 
                    777:   Revision 1.92  2003/06/25 16:30:45  brouard
                    778:   (Module): On windows (cygwin) function asctime_r doesn't
                    779:   exist so I changed back to asctime which exists.
                    780: 
                    781:   Revision 1.91  2003/06/25 15:30:29  brouard
                    782:   * imach.c (Repository): Duplicated warning errors corrected.
                    783:   (Repository): Elapsed time after each iteration is now output. It
                    784:   helps to forecast when convergence will be reached. Elapsed time
                    785:   is stamped in powell.  We created a new html file for the graphs
                    786:   concerning matrix of covariance. It has extension -cov.htm.
                    787: 
                    788:   Revision 1.90  2003/06/24 12:34:15  brouard
                    789:   (Module): Some bugs corrected for windows. Also, when
                    790:   mle=-1 a template is output in file "or"mypar.txt with the design
                    791:   of the covariance matrix to be input.
                    792: 
                    793:   Revision 1.89  2003/06/24 12:30:52  brouard
                    794:   (Module): Some bugs corrected for windows. Also, when
                    795:   mle=-1 a template is output in file "or"mypar.txt with the design
                    796:   of the covariance matrix to be input.
                    797: 
                    798:   Revision 1.88  2003/06/23 17:54:56  brouard
                    799:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    800: 
                    801:   Revision 1.87  2003/06/18 12:26:01  brouard
                    802:   Version 0.96
                    803: 
                    804:   Revision 1.86  2003/06/17 20:04:08  brouard
                    805:   (Module): Change position of html and gnuplot routines and added
                    806:   routine fileappend.
                    807: 
                    808:   Revision 1.85  2003/06/17 13:12:43  brouard
                    809:   * imach.c (Repository): Check when date of death was earlier that
                    810:   current date of interview. It may happen when the death was just
                    811:   prior to the death. In this case, dh was negative and likelihood
                    812:   was wrong (infinity). We still send an "Error" but patch by
                    813:   assuming that the date of death was just one stepm after the
                    814:   interview.
                    815:   (Repository): Because some people have very long ID (first column)
                    816:   we changed int to long in num[] and we added a new lvector for
                    817:   memory allocation. But we also truncated to 8 characters (left
                    818:   truncation)
                    819:   (Repository): No more line truncation errors.
                    820: 
                    821:   Revision 1.84  2003/06/13 21:44:43  brouard
                    822:   * imach.c (Repository): Replace "freqsummary" at a correct
                    823:   place. It differs from routine "prevalence" which may be called
                    824:   many times. Probs is memory consuming and must be used with
                    825:   parcimony.
                    826:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    827: 
                    828:   Revision 1.83  2003/06/10 13:39:11  lievre
                    829:   *** empty log message ***
                    830: 
                    831:   Revision 1.82  2003/06/05 15:57:20  brouard
                    832:   Add log in  imach.c and  fullversion number is now printed.
                    833: 
                    834: */
                    835: /*
                    836:    Interpolated Markov Chain
                    837: 
                    838:   Short summary of the programme:
                    839:   
1.227     brouard   840:   This program computes Healthy Life Expectancies or State-specific
                    841:   (if states aren't health statuses) Expectancies from
                    842:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    843: 
                    844:   -1- a first survey ("cross") where individuals from different ages
                    845:   are interviewed on their health status or degree of disability (in
                    846:   the case of a health survey which is our main interest)
                    847: 
                    848:   -2- at least a second wave of interviews ("longitudinal") which
                    849:   measure each change (if any) in individual health status.  Health
                    850:   expectancies are computed from the time spent in each health state
                    851:   according to a model. More health states you consider, more time is
                    852:   necessary to reach the Maximum Likelihood of the parameters involved
                    853:   in the model.  The simplest model is the multinomial logistic model
                    854:   where pij is the probability to be observed in state j at the second
                    855:   wave conditional to be observed in state i at the first
                    856:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    857:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    858:   have a more complex model than "constant and age", you should modify
                    859:   the program where the markup *Covariates have to be included here
                    860:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   861:   convergence.
                    862: 
                    863:   The advantage of this computer programme, compared to a simple
                    864:   multinomial logistic model, is clear when the delay between waves is not
                    865:   identical for each individual. Also, if a individual missed an
                    866:   intermediate interview, the information is lost, but taken into
                    867:   account using an interpolation or extrapolation.  
                    868: 
                    869:   hPijx is the probability to be observed in state i at age x+h
                    870:   conditional to the observed state i at age x. The delay 'h' can be
                    871:   split into an exact number (nh*stepm) of unobserved intermediate
                    872:   states. This elementary transition (by month, quarter,
                    873:   semester or year) is modelled as a multinomial logistic.  The hPx
                    874:   matrix is simply the matrix product of nh*stepm elementary matrices
                    875:   and the contribution of each individual to the likelihood is simply
                    876:   hPijx.
                    877: 
                    878:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   879:   of the life expectancies. It also computes the period (stable) prevalence.
                    880: 
                    881: Back prevalence and projections:
1.227     brouard   882: 
                    883:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    884:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    885:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    886:    mobilavproj)
                    887: 
                    888:     Computes the back prevalence limit for any combination of
                    889:     covariate values k at any age between ageminpar and agemaxpar and
                    890:     returns it in **bprlim. In the loops,
                    891: 
                    892:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    893:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    894: 
                    895:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   896:    Computes for any combination of covariates k and any age between bage and fage 
                    897:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    898:                        oldm=oldms;savm=savms;
1.227     brouard   899: 
1.267     brouard   900:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   901:      Computes the transition matrix starting at age 'age' over
                    902:      'nhstepm*hstepm*stepm' months (i.e. until
                    903:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   904:      nhstepm*hstepm matrices. 
                    905: 
                    906:      Returns p3mat[i][j][h] after calling
                    907:      p3mat[i][j][h]=matprod2(newm,
                    908:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    909:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    910:      oldm);
1.226     brouard   911: 
                    912: Important routines
                    913: 
                    914: - func (or funcone), computes logit (pij) distinguishing
                    915:   o fixed variables (single or product dummies or quantitative);
                    916:   o varying variables by:
                    917:    (1) wave (single, product dummies, quantitative), 
                    918:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    919:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    920:        % varying dummy (not done) or quantitative (not done);
                    921: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    922:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    923: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    924:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    925:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   926: 
1.226     brouard   927: 
                    928:   
1.133     brouard   929:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    930:            Institut national d'études démographiques, Paris.
1.126     brouard   931:   This software have been partly granted by Euro-REVES, a concerted action
                    932:   from the European Union.
                    933:   It is copyrighted identically to a GNU software product, ie programme and
                    934:   software can be distributed freely for non commercial use. Latest version
                    935:   can be accessed at http://euroreves.ined.fr/imach .
                    936: 
                    937:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    938:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    939:   
                    940:   **********************************************************************/
                    941: /*
                    942:   main
                    943:   read parameterfile
                    944:   read datafile
                    945:   concatwav
                    946:   freqsummary
                    947:   if (mle >= 1)
                    948:     mlikeli
                    949:   print results files
                    950:   if mle==1 
                    951:      computes hessian
                    952:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    953:       begin-prev-date,...
                    954:   open gnuplot file
                    955:   open html file
1.145     brouard   956:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    957:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    958:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    959:     freexexit2 possible for memory heap.
                    960: 
                    961:   h Pij x                         | pij_nom  ficrestpij
                    962:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    963:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    964:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    965: 
                    966:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    967:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    968:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    969:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    970:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    971: 
1.126     brouard   972:   forecasting if prevfcast==1 prevforecast call prevalence()
                    973:   health expectancies
                    974:   Variance-covariance of DFLE
                    975:   prevalence()
                    976:    movingaverage()
                    977:   varevsij() 
                    978:   if popbased==1 varevsij(,popbased)
                    979:   total life expectancies
                    980:   Variance of period (stable) prevalence
                    981:  end
                    982: */
                    983: 
1.187     brouard   984: /* #define DEBUG */
                    985: /* #define DEBUGBRENT */
1.203     brouard   986: /* #define DEBUGLINMIN */
                    987: /* #define DEBUGHESS */
                    988: #define DEBUGHESSIJ
1.224     brouard   989: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   990: #define POWELL /* Instead of NLOPT */
1.224     brouard   991: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard   992: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                    993: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard   994: 
                    995: #include <math.h>
                    996: #include <stdio.h>
                    997: #include <stdlib.h>
                    998: #include <string.h>
1.226     brouard   999: #include <ctype.h>
1.159     brouard  1000: 
                   1001: #ifdef _WIN32
                   1002: #include <io.h>
1.172     brouard  1003: #include <windows.h>
                   1004: #include <tchar.h>
1.159     brouard  1005: #else
1.126     brouard  1006: #include <unistd.h>
1.159     brouard  1007: #endif
1.126     brouard  1008: 
                   1009: #include <limits.h>
                   1010: #include <sys/types.h>
1.171     brouard  1011: 
                   1012: #if defined(__GNUC__)
                   1013: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1014: #endif
                   1015: 
1.126     brouard  1016: #include <sys/stat.h>
                   1017: #include <errno.h>
1.159     brouard  1018: /* extern int errno; */
1.126     brouard  1019: 
1.157     brouard  1020: /* #ifdef LINUX */
                   1021: /* #include <time.h> */
                   1022: /* #include "timeval.h" */
                   1023: /* #else */
                   1024: /* #include <sys/time.h> */
                   1025: /* #endif */
                   1026: 
1.126     brouard  1027: #include <time.h>
                   1028: 
1.136     brouard  1029: #ifdef GSL
                   1030: #include <gsl/gsl_errno.h>
                   1031: #include <gsl/gsl_multimin.h>
                   1032: #endif
                   1033: 
1.167     brouard  1034: 
1.162     brouard  1035: #ifdef NLOPT
                   1036: #include <nlopt.h>
                   1037: typedef struct {
                   1038:   double (* function)(double [] );
                   1039: } myfunc_data ;
                   1040: #endif
                   1041: 
1.126     brouard  1042: /* #include <libintl.h> */
                   1043: /* #define _(String) gettext (String) */
                   1044: 
1.251     brouard  1045: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1046: 
                   1047: #define GNUPLOTPROGRAM "gnuplot"
                   1048: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1049: #define FILENAMELENGTH 132
                   1050: 
                   1051: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1052: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1053: 
1.144     brouard  1054: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1055: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1056: 
                   1057: #define NINTERVMAX 8
1.144     brouard  1058: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1059: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.291     brouard  1060: #define NCOVMAX 20  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1061: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1062: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1063: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1064: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1065: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1066: /* #define AGESUP 130 */
1.288     brouard  1067: /* #define AGESUP 150 */
                   1068: #define AGESUP 200
1.268     brouard  1069: #define AGEINF 0
1.218     brouard  1070: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1071: #define AGEBASE 40
1.194     brouard  1072: #define AGEOVERFLOW 1.e20
1.164     brouard  1073: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1074: #ifdef _WIN32
                   1075: #define DIRSEPARATOR '\\'
                   1076: #define CHARSEPARATOR "\\"
                   1077: #define ODIRSEPARATOR '/'
                   1078: #else
1.126     brouard  1079: #define DIRSEPARATOR '/'
                   1080: #define CHARSEPARATOR "/"
                   1081: #define ODIRSEPARATOR '\\'
                   1082: #endif
                   1083: 
1.292   ! brouard  1084: /* $Id: imach.c,v 1.291 2019/05/09 13:44:18 brouard Exp $ */
1.126     brouard  1085: /* $State: Exp $ */
1.196     brouard  1086: #include "version.h"
                   1087: char version[]=__IMACH_VERSION__;
1.283     brouard  1088: char copyright[]="April 2018,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.292   ! brouard  1089: char fullversion[]="$Revision: 1.291 $ $Date: 2019/05/09 13:44:18 $"; 
1.126     brouard  1090: char strstart[80];
                   1091: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1092: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1093: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1094: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1095: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1096: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1097: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1098: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1099: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1100: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1101: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1102: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1103: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1104: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1105: int nsd=0; /**< Total number of single dummy variables (output) */
                   1106: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1107: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1108: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1109: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1110: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1111: int cptcov=0; /* Working variable */
1.290     brouard  1112: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1113: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1114: int npar=NPARMAX;
                   1115: int nlstate=2; /* Number of live states */
                   1116: int ndeath=1; /* Number of dead states */
1.130     brouard  1117: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1118: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1119: int popbased=0;
                   1120: 
                   1121: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1122: int maxwav=0; /* Maxim number of waves */
                   1123: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1124: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1125: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1126:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1127: int mle=1, weightopt=0;
1.126     brouard  1128: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1129: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1130: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1131:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1132: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1133: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1134: 
1.130     brouard  1135: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1136: double **matprod2(); /* test */
1.126     brouard  1137: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1138: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1139: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1140: 
1.136     brouard  1141: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1142: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1143: FILE *ficlog, *ficrespow;
1.130     brouard  1144: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1145: double fretone; /* Only one call to likelihood */
1.130     brouard  1146: long ipmx=0; /* Number of contributions */
1.126     brouard  1147: double sw; /* Sum of weights */
                   1148: char filerespow[FILENAMELENGTH];
                   1149: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1150: FILE *ficresilk;
                   1151: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1152: FILE *ficresprobmorprev;
                   1153: FILE *fichtm, *fichtmcov; /* Html File */
                   1154: FILE *ficreseij;
                   1155: char filerese[FILENAMELENGTH];
                   1156: FILE *ficresstdeij;
                   1157: char fileresstde[FILENAMELENGTH];
                   1158: FILE *ficrescveij;
                   1159: char filerescve[FILENAMELENGTH];
                   1160: FILE  *ficresvij;
                   1161: char fileresv[FILENAMELENGTH];
1.269     brouard  1162: 
1.126     brouard  1163: char title[MAXLINE];
1.234     brouard  1164: char model[MAXLINE]; /**< The model line */
1.217     brouard  1165: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1166: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1167: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1168: char command[FILENAMELENGTH];
                   1169: int  outcmd=0;
                   1170: 
1.217     brouard  1171: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1172: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1173: char filelog[FILENAMELENGTH]; /* Log file */
                   1174: char filerest[FILENAMELENGTH];
                   1175: char fileregp[FILENAMELENGTH];
                   1176: char popfile[FILENAMELENGTH];
                   1177: 
                   1178: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1179: 
1.157     brouard  1180: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1181: /* struct timezone tzp; */
                   1182: /* extern int gettimeofday(); */
                   1183: struct tm tml, *gmtime(), *localtime();
                   1184: 
                   1185: extern time_t time();
                   1186: 
                   1187: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1188: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1189: struct tm tm;
                   1190: 
1.126     brouard  1191: char strcurr[80], strfor[80];
                   1192: 
                   1193: char *endptr;
                   1194: long lval;
                   1195: double dval;
                   1196: 
                   1197: #define NR_END 1
                   1198: #define FREE_ARG char*
                   1199: #define FTOL 1.0e-10
                   1200: 
                   1201: #define NRANSI 
1.240     brouard  1202: #define ITMAX 200
                   1203: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1204: 
                   1205: #define TOL 2.0e-4 
                   1206: 
                   1207: #define CGOLD 0.3819660 
                   1208: #define ZEPS 1.0e-10 
                   1209: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1210: 
                   1211: #define GOLD 1.618034 
                   1212: #define GLIMIT 100.0 
                   1213: #define TINY 1.0e-20 
                   1214: 
                   1215: static double maxarg1,maxarg2;
                   1216: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1217: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1218:   
                   1219: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1220: #define rint(a) floor(a+0.5)
1.166     brouard  1221: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1222: #define mytinydouble 1.0e-16
1.166     brouard  1223: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1224: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1225: /* static double dsqrarg; */
                   1226: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1227: static double sqrarg;
                   1228: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1229: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1230: int agegomp= AGEGOMP;
                   1231: 
                   1232: int imx; 
                   1233: int stepm=1;
                   1234: /* Stepm, step in month: minimum step interpolation*/
                   1235: 
                   1236: int estepm;
                   1237: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1238: 
                   1239: int m,nb;
                   1240: long *num;
1.197     brouard  1241: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1242: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1243:                   covariate for which somebody answered excluding 
                   1244:                   undefined. Usually 2: 0 and 1. */
                   1245: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1246:                             covariate for which somebody answered including 
                   1247:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1248: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1249: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1250: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1251: double *ageexmed,*agecens;
                   1252: double dateintmean=0;
                   1253: 
                   1254: double *weight;
                   1255: int **s; /* Status */
1.141     brouard  1256: double *agedc;
1.145     brouard  1257: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1258:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1259:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1260: double **coqvar; /* Fixed quantitative covariate nqv */
                   1261: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1262: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1263: double  idx; 
                   1264: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1265: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1266: /*k          1  2   3   4     5    6    7     8    9 */
                   1267: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1268: /* Tndvar[k]    1   2   3               4          5 */
                   1269: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1270: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1271: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1272: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1273: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1274: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1275: /* Tprod[i]=k           4               7            */
                   1276: /* Tage[i]=k                  5               8      */
                   1277: /* */
                   1278: /* Type                    */
                   1279: /* V         1  2  3  4  5 */
                   1280: /*           F  F  V  V  V */
                   1281: /*           D  Q  D  D  Q */
                   1282: /*                         */
                   1283: int *TvarsD;
                   1284: int *TvarsDind;
                   1285: int *TvarsQ;
                   1286: int *TvarsQind;
                   1287: 
1.235     brouard  1288: #define MAXRESULTLINES 10
                   1289: int nresult=0;
1.258     brouard  1290: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1291: int TKresult[MAXRESULTLINES];
1.237     brouard  1292: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1293: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1294: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1295: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1296: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1297: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1298: 
1.234     brouard  1299: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1300: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1301: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1302: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1303: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1304: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1305: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1306: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1307: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1308: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1309: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1310: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1311: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1312: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1313: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1314: 
1.230     brouard  1315: int *Tvarsel; /**< Selected covariates for output */
                   1316: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1317: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1318: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1319: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1320: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1321: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1322: int *Tage;
1.227     brouard  1323: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1324: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1325: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1326: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1327: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1328: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1329: int **Tvard;
                   1330: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1331: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1332: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1333:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1334:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1335: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1336: double *lsurv, *lpop, *tpop;
                   1337: 
1.231     brouard  1338: #define FD 1; /* Fixed dummy covariate */
                   1339: #define FQ 2; /* Fixed quantitative covariate */
                   1340: #define FP 3; /* Fixed product covariate */
                   1341: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1342: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1343: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1344: #define VD 10; /* Varying dummy covariate */
                   1345: #define VQ 11; /* Varying quantitative covariate */
                   1346: #define VP 12; /* Varying product covariate */
                   1347: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1348: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1349: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1350: #define APFD 16; /* Age product * fixed dummy covariate */
                   1351: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1352: #define APVD 18; /* Age product * varying dummy covariate */
                   1353: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1354: 
                   1355: #define FTYPE 1; /* Fixed covariate */
                   1356: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1357: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1358: 
                   1359: struct kmodel{
                   1360:        int maintype; /* main type */
                   1361:        int subtype; /* subtype */
                   1362: };
                   1363: struct kmodel modell[NCOVMAX];
                   1364: 
1.143     brouard  1365: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1366: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1367: 
                   1368: /**************** split *************************/
                   1369: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1370: {
                   1371:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1372:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1373:   */ 
                   1374:   char *ss;                            /* pointer */
1.186     brouard  1375:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1376: 
                   1377:   l1 = strlen(path );                  /* length of path */
                   1378:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1379:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1380:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1381:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1382:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1383:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1384:     /* get current working directory */
                   1385:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1386: #ifdef WIN32
                   1387:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1388: #else
                   1389:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1390: #endif
1.126     brouard  1391:       return( GLOCK_ERROR_GETCWD );
                   1392:     }
                   1393:     /* got dirc from getcwd*/
                   1394:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1395:   } else {                             /* strip directory from path */
1.126     brouard  1396:     ss++;                              /* after this, the filename */
                   1397:     l2 = strlen( ss );                 /* length of filename */
                   1398:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1399:     strcpy( name, ss );                /* save file name */
                   1400:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1401:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1402:     printf(" DIRC2 = %s \n",dirc);
                   1403:   }
                   1404:   /* We add a separator at the end of dirc if not exists */
                   1405:   l1 = strlen( dirc );                 /* length of directory */
                   1406:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1407:     dirc[l1] =  DIRSEPARATOR;
                   1408:     dirc[l1+1] = 0; 
                   1409:     printf(" DIRC3 = %s \n",dirc);
                   1410:   }
                   1411:   ss = strrchr( name, '.' );           /* find last / */
                   1412:   if (ss >0){
                   1413:     ss++;
                   1414:     strcpy(ext,ss);                    /* save extension */
                   1415:     l1= strlen( name);
                   1416:     l2= strlen(ss)+1;
                   1417:     strncpy( finame, name, l1-l2);
                   1418:     finame[l1-l2]= 0;
                   1419:   }
                   1420: 
                   1421:   return( 0 );                         /* we're done */
                   1422: }
                   1423: 
                   1424: 
                   1425: /******************************************/
                   1426: 
                   1427: void replace_back_to_slash(char *s, char*t)
                   1428: {
                   1429:   int i;
                   1430:   int lg=0;
                   1431:   i=0;
                   1432:   lg=strlen(t);
                   1433:   for(i=0; i<= lg; i++) {
                   1434:     (s[i] = t[i]);
                   1435:     if (t[i]== '\\') s[i]='/';
                   1436:   }
                   1437: }
                   1438: 
1.132     brouard  1439: char *trimbb(char *out, char *in)
1.137     brouard  1440: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1441:   char *s;
                   1442:   s=out;
                   1443:   while (*in != '\0'){
1.137     brouard  1444:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1445:       in++;
                   1446:     }
                   1447:     *out++ = *in++;
                   1448:   }
                   1449:   *out='\0';
                   1450:   return s;
                   1451: }
                   1452: 
1.187     brouard  1453: /* char *substrchaine(char *out, char *in, char *chain) */
                   1454: /* { */
                   1455: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1456: /*   char *s, *t; */
                   1457: /*   t=in;s=out; */
                   1458: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1459: /*     *out++ = *in++; */
                   1460: /*   } */
                   1461: 
                   1462: /*   /\* *in matches *chain *\/ */
                   1463: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1464: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1465: /*   } */
                   1466: /*   in--; chain--; */
                   1467: /*   while ( (*in != '\0')){ */
                   1468: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1469: /*     *out++ = *in++; */
                   1470: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1471: /*   } */
                   1472: /*   *out='\0'; */
                   1473: /*   out=s; */
                   1474: /*   return out; */
                   1475: /* } */
                   1476: char *substrchaine(char *out, char *in, char *chain)
                   1477: {
                   1478:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1479:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1480: 
                   1481:   char *strloc;
                   1482: 
                   1483:   strcpy (out, in); 
                   1484:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1485:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1486:   if(strloc != NULL){ 
                   1487:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1488:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1489:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1490:   }
                   1491:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1492:   return out;
                   1493: }
                   1494: 
                   1495: 
1.145     brouard  1496: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1497: {
1.187     brouard  1498:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1499:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1500:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1501:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1502:   */
1.160     brouard  1503:   char *s, *t;
1.145     brouard  1504:   t=in;s=in;
                   1505:   while ((*in != occ) && (*in != '\0')){
                   1506:     *alocc++ = *in++;
                   1507:   }
                   1508:   if( *in == occ){
                   1509:     *(alocc)='\0';
                   1510:     s=++in;
                   1511:   }
                   1512:  
                   1513:   if (s == t) {/* occ not found */
                   1514:     *(alocc-(in-s))='\0';
                   1515:     in=s;
                   1516:   }
                   1517:   while ( *in != '\0'){
                   1518:     *blocc++ = *in++;
                   1519:   }
                   1520: 
                   1521:   *blocc='\0';
                   1522:   return t;
                   1523: }
1.137     brouard  1524: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1525: {
1.187     brouard  1526:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1527:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1528:      gives blocc="abcdef2ghi" and alocc="j".
                   1529:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1530:   */
                   1531:   char *s, *t;
                   1532:   t=in;s=in;
                   1533:   while (*in != '\0'){
                   1534:     while( *in == occ){
                   1535:       *blocc++ = *in++;
                   1536:       s=in;
                   1537:     }
                   1538:     *blocc++ = *in++;
                   1539:   }
                   1540:   if (s == t) /* occ not found */
                   1541:     *(blocc-(in-s))='\0';
                   1542:   else
                   1543:     *(blocc-(in-s)-1)='\0';
                   1544:   in=s;
                   1545:   while ( *in != '\0'){
                   1546:     *alocc++ = *in++;
                   1547:   }
                   1548: 
                   1549:   *alocc='\0';
                   1550:   return s;
                   1551: }
                   1552: 
1.126     brouard  1553: int nbocc(char *s, char occ)
                   1554: {
                   1555:   int i,j=0;
                   1556:   int lg=20;
                   1557:   i=0;
                   1558:   lg=strlen(s);
                   1559:   for(i=0; i<= lg; i++) {
1.234     brouard  1560:     if  (s[i] == occ ) j++;
1.126     brouard  1561:   }
                   1562:   return j;
                   1563: }
                   1564: 
1.137     brouard  1565: /* void cutv(char *u,char *v, char*t, char occ) */
                   1566: /* { */
                   1567: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1568: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1569: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1570: /*   int i,lg,j,p=0; */
                   1571: /*   i=0; */
                   1572: /*   lg=strlen(t); */
                   1573: /*   for(j=0; j<=lg-1; j++) { */
                   1574: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1575: /*   } */
1.126     brouard  1576: 
1.137     brouard  1577: /*   for(j=0; j<p; j++) { */
                   1578: /*     (u[j] = t[j]); */
                   1579: /*   } */
                   1580: /*      u[p]='\0'; */
1.126     brouard  1581: 
1.137     brouard  1582: /*    for(j=0; j<= lg; j++) { */
                   1583: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1584: /*   } */
                   1585: /* } */
1.126     brouard  1586: 
1.160     brouard  1587: #ifdef _WIN32
                   1588: char * strsep(char **pp, const char *delim)
                   1589: {
                   1590:   char *p, *q;
                   1591:          
                   1592:   if ((p = *pp) == NULL)
                   1593:     return 0;
                   1594:   if ((q = strpbrk (p, delim)) != NULL)
                   1595:   {
                   1596:     *pp = q + 1;
                   1597:     *q = '\0';
                   1598:   }
                   1599:   else
                   1600:     *pp = 0;
                   1601:   return p;
                   1602: }
                   1603: #endif
                   1604: 
1.126     brouard  1605: /********************** nrerror ********************/
                   1606: 
                   1607: void nrerror(char error_text[])
                   1608: {
                   1609:   fprintf(stderr,"ERREUR ...\n");
                   1610:   fprintf(stderr,"%s\n",error_text);
                   1611:   exit(EXIT_FAILURE);
                   1612: }
                   1613: /*********************** vector *******************/
                   1614: double *vector(int nl, int nh)
                   1615: {
                   1616:   double *v;
                   1617:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1618:   if (!v) nrerror("allocation failure in vector");
                   1619:   return v-nl+NR_END;
                   1620: }
                   1621: 
                   1622: /************************ free vector ******************/
                   1623: void free_vector(double*v, int nl, int nh)
                   1624: {
                   1625:   free((FREE_ARG)(v+nl-NR_END));
                   1626: }
                   1627: 
                   1628: /************************ivector *******************************/
                   1629: int *ivector(long nl,long nh)
                   1630: {
                   1631:   int *v;
                   1632:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1633:   if (!v) nrerror("allocation failure in ivector");
                   1634:   return v-nl+NR_END;
                   1635: }
                   1636: 
                   1637: /******************free ivector **************************/
                   1638: void free_ivector(int *v, long nl, long nh)
                   1639: {
                   1640:   free((FREE_ARG)(v+nl-NR_END));
                   1641: }
                   1642: 
                   1643: /************************lvector *******************************/
                   1644: long *lvector(long nl,long nh)
                   1645: {
                   1646:   long *v;
                   1647:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1648:   if (!v) nrerror("allocation failure in ivector");
                   1649:   return v-nl+NR_END;
                   1650: }
                   1651: 
                   1652: /******************free lvector **************************/
                   1653: void free_lvector(long *v, long nl, long nh)
                   1654: {
                   1655:   free((FREE_ARG)(v+nl-NR_END));
                   1656: }
                   1657: 
                   1658: /******************* imatrix *******************************/
                   1659: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1660:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1661: { 
                   1662:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1663:   int **m; 
                   1664:   
                   1665:   /* allocate pointers to rows */ 
                   1666:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1667:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1668:   m += NR_END; 
                   1669:   m -= nrl; 
                   1670:   
                   1671:   
                   1672:   /* allocate rows and set pointers to them */ 
                   1673:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1674:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1675:   m[nrl] += NR_END; 
                   1676:   m[nrl] -= ncl; 
                   1677:   
                   1678:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1679:   
                   1680:   /* return pointer to array of pointers to rows */ 
                   1681:   return m; 
                   1682: } 
                   1683: 
                   1684: /****************** free_imatrix *************************/
                   1685: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1686:       int **m;
                   1687:       long nch,ncl,nrh,nrl; 
                   1688:      /* free an int matrix allocated by imatrix() */ 
                   1689: { 
                   1690:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1691:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1692: } 
                   1693: 
                   1694: /******************* matrix *******************************/
                   1695: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1696: {
                   1697:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1698:   double **m;
                   1699: 
                   1700:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1701:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1702:   m += NR_END;
                   1703:   m -= nrl;
                   1704: 
                   1705:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1706:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1707:   m[nrl] += NR_END;
                   1708:   m[nrl] -= ncl;
                   1709: 
                   1710:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1711:   return m;
1.145     brouard  1712:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1713: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1714: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1715:    */
                   1716: }
                   1717: 
                   1718: /*************************free matrix ************************/
                   1719: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1720: {
                   1721:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1722:   free((FREE_ARG)(m+nrl-NR_END));
                   1723: }
                   1724: 
                   1725: /******************* ma3x *******************************/
                   1726: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1727: {
                   1728:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1729:   double ***m;
                   1730: 
                   1731:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1732:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1733:   m += NR_END;
                   1734:   m -= nrl;
                   1735: 
                   1736:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1737:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1738:   m[nrl] += NR_END;
                   1739:   m[nrl] -= ncl;
                   1740: 
                   1741:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1742: 
                   1743:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1744:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1745:   m[nrl][ncl] += NR_END;
                   1746:   m[nrl][ncl] -= nll;
                   1747:   for (j=ncl+1; j<=nch; j++) 
                   1748:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1749:   
                   1750:   for (i=nrl+1; i<=nrh; i++) {
                   1751:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1752:     for (j=ncl+1; j<=nch; j++) 
                   1753:       m[i][j]=m[i][j-1]+nlay;
                   1754:   }
                   1755:   return m; 
                   1756:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1757:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1758:   */
                   1759: }
                   1760: 
                   1761: /*************************free ma3x ************************/
                   1762: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1763: {
                   1764:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1765:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1766:   free((FREE_ARG)(m+nrl-NR_END));
                   1767: }
                   1768: 
                   1769: /*************** function subdirf ***********/
                   1770: char *subdirf(char fileres[])
                   1771: {
                   1772:   /* Caution optionfilefiname is hidden */
                   1773:   strcpy(tmpout,optionfilefiname);
                   1774:   strcat(tmpout,"/"); /* Add to the right */
                   1775:   strcat(tmpout,fileres);
                   1776:   return tmpout;
                   1777: }
                   1778: 
                   1779: /*************** function subdirf2 ***********/
                   1780: char *subdirf2(char fileres[], char *preop)
                   1781: {
                   1782:   
                   1783:   /* Caution optionfilefiname is hidden */
                   1784:   strcpy(tmpout,optionfilefiname);
                   1785:   strcat(tmpout,"/");
                   1786:   strcat(tmpout,preop);
                   1787:   strcat(tmpout,fileres);
                   1788:   return tmpout;
                   1789: }
                   1790: 
                   1791: /*************** function subdirf3 ***********/
                   1792: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1793: {
                   1794:   
                   1795:   /* Caution optionfilefiname is hidden */
                   1796:   strcpy(tmpout,optionfilefiname);
                   1797:   strcat(tmpout,"/");
                   1798:   strcat(tmpout,preop);
                   1799:   strcat(tmpout,preop2);
                   1800:   strcat(tmpout,fileres);
                   1801:   return tmpout;
                   1802: }
1.213     brouard  1803:  
                   1804: /*************** function subdirfext ***********/
                   1805: char *subdirfext(char fileres[], char *preop, char *postop)
                   1806: {
                   1807:   
                   1808:   strcpy(tmpout,preop);
                   1809:   strcat(tmpout,fileres);
                   1810:   strcat(tmpout,postop);
                   1811:   return tmpout;
                   1812: }
1.126     brouard  1813: 
1.213     brouard  1814: /*************** function subdirfext3 ***********/
                   1815: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1816: {
                   1817:   
                   1818:   /* Caution optionfilefiname is hidden */
                   1819:   strcpy(tmpout,optionfilefiname);
                   1820:   strcat(tmpout,"/");
                   1821:   strcat(tmpout,preop);
                   1822:   strcat(tmpout,fileres);
                   1823:   strcat(tmpout,postop);
                   1824:   return tmpout;
                   1825: }
                   1826:  
1.162     brouard  1827: char *asc_diff_time(long time_sec, char ascdiff[])
                   1828: {
                   1829:   long sec_left, days, hours, minutes;
                   1830:   days = (time_sec) / (60*60*24);
                   1831:   sec_left = (time_sec) % (60*60*24);
                   1832:   hours = (sec_left) / (60*60) ;
                   1833:   sec_left = (sec_left) %(60*60);
                   1834:   minutes = (sec_left) /60;
                   1835:   sec_left = (sec_left) % (60);
                   1836:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1837:   return ascdiff;
                   1838: }
                   1839: 
1.126     brouard  1840: /***************** f1dim *************************/
                   1841: extern int ncom; 
                   1842: extern double *pcom,*xicom;
                   1843: extern double (*nrfunc)(double []); 
                   1844:  
                   1845: double f1dim(double x) 
                   1846: { 
                   1847:   int j; 
                   1848:   double f;
                   1849:   double *xt; 
                   1850:  
                   1851:   xt=vector(1,ncom); 
                   1852:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1853:   f=(*nrfunc)(xt); 
                   1854:   free_vector(xt,1,ncom); 
                   1855:   return f; 
                   1856: } 
                   1857: 
                   1858: /*****************brent *************************/
                   1859: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1860: {
                   1861:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1862:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1863:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1864:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1865:    * returned function value. 
                   1866:   */
1.126     brouard  1867:   int iter; 
                   1868:   double a,b,d,etemp;
1.159     brouard  1869:   double fu=0,fv,fw,fx;
1.164     brouard  1870:   double ftemp=0.;
1.126     brouard  1871:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1872:   double e=0.0; 
                   1873:  
                   1874:   a=(ax < cx ? ax : cx); 
                   1875:   b=(ax > cx ? ax : cx); 
                   1876:   x=w=v=bx; 
                   1877:   fw=fv=fx=(*f)(x); 
                   1878:   for (iter=1;iter<=ITMAX;iter++) { 
                   1879:     xm=0.5*(a+b); 
                   1880:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1881:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1882:     printf(".");fflush(stdout);
                   1883:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1884: #ifdef DEBUGBRENT
1.126     brouard  1885:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1886:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1887:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1888: #endif
                   1889:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1890:       *xmin=x; 
                   1891:       return fx; 
                   1892:     } 
                   1893:     ftemp=fu;
                   1894:     if (fabs(e) > tol1) { 
                   1895:       r=(x-w)*(fx-fv); 
                   1896:       q=(x-v)*(fx-fw); 
                   1897:       p=(x-v)*q-(x-w)*r; 
                   1898:       q=2.0*(q-r); 
                   1899:       if (q > 0.0) p = -p; 
                   1900:       q=fabs(q); 
                   1901:       etemp=e; 
                   1902:       e=d; 
                   1903:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1904:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1905:       else { 
1.224     brouard  1906:                                d=p/q; 
                   1907:                                u=x+d; 
                   1908:                                if (u-a < tol2 || b-u < tol2) 
                   1909:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1910:       } 
                   1911:     } else { 
                   1912:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1913:     } 
                   1914:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1915:     fu=(*f)(u); 
                   1916:     if (fu <= fx) { 
                   1917:       if (u >= x) a=x; else b=x; 
                   1918:       SHFT(v,w,x,u) 
1.183     brouard  1919:       SHFT(fv,fw,fx,fu) 
                   1920:     } else { 
                   1921:       if (u < x) a=u; else b=u; 
                   1922:       if (fu <= fw || w == x) { 
1.224     brouard  1923:                                v=w; 
                   1924:                                w=u; 
                   1925:                                fv=fw; 
                   1926:                                fw=fu; 
1.183     brouard  1927:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1928:                                v=u; 
                   1929:                                fv=fu; 
1.183     brouard  1930:       } 
                   1931:     } 
1.126     brouard  1932:   } 
                   1933:   nrerror("Too many iterations in brent"); 
                   1934:   *xmin=x; 
                   1935:   return fx; 
                   1936: } 
                   1937: 
                   1938: /****************** mnbrak ***********************/
                   1939: 
                   1940: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1941:            double (*func)(double)) 
1.183     brouard  1942: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1943: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1944: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1945: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1946:    */
1.126     brouard  1947:   double ulim,u,r,q, dum;
                   1948:   double fu; 
1.187     brouard  1949: 
                   1950:   double scale=10.;
                   1951:   int iterscale=0;
                   1952: 
                   1953:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1954:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1955: 
                   1956: 
                   1957:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1958:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1959:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1960:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1961:   /* } */
                   1962: 
1.126     brouard  1963:   if (*fb > *fa) { 
                   1964:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1965:     SHFT(dum,*fb,*fa,dum) 
                   1966:   } 
1.126     brouard  1967:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1968:   *fc=(*func)(*cx); 
1.183     brouard  1969: #ifdef DEBUG
1.224     brouard  1970:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1971:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1972: #endif
1.224     brouard  1973:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1974:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1975:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1976:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1977:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1978:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1979:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1980:       fu=(*func)(u); 
1.163     brouard  1981: #ifdef DEBUG
                   1982:       /* f(x)=A(x-u)**2+f(u) */
                   1983:       double A, fparabu; 
                   1984:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1985:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1986:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1987:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1988:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1989:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1990:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   1991:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  1992: #endif 
1.184     brouard  1993: #ifdef MNBRAKORIGINAL
1.183     brouard  1994: #else
1.191     brouard  1995: /*       if (fu > *fc) { */
                   1996: /* #ifdef DEBUG */
                   1997: /*       printf("mnbrak4  fu > fc \n"); */
                   1998: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   1999: /* #endif */
                   2000: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2001: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2002: /*     dum=u; /\* Shifting c and u *\/ */
                   2003: /*     u = *cx; */
                   2004: /*     *cx = dum; */
                   2005: /*     dum = fu; */
                   2006: /*     fu = *fc; */
                   2007: /*     *fc =dum; */
                   2008: /*       } else { /\* end *\/ */
                   2009: /* #ifdef DEBUG */
                   2010: /*       printf("mnbrak3  fu < fc \n"); */
                   2011: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2012: /* #endif */
                   2013: /*     dum=u; /\* Shifting c and u *\/ */
                   2014: /*     u = *cx; */
                   2015: /*     *cx = dum; */
                   2016: /*     dum = fu; */
                   2017: /*     fu = *fc; */
                   2018: /*     *fc =dum; */
                   2019: /*       } */
1.224     brouard  2020: #ifdef DEBUGMNBRAK
                   2021:                 double A, fparabu; 
                   2022:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2023:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2024:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2025:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2026: #endif
1.191     brouard  2027:       dum=u; /* Shifting c and u */
                   2028:       u = *cx;
                   2029:       *cx = dum;
                   2030:       dum = fu;
                   2031:       fu = *fc;
                   2032:       *fc =dum;
1.183     brouard  2033: #endif
1.162     brouard  2034:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2035: #ifdef DEBUG
1.224     brouard  2036:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2037:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2038: #endif
1.126     brouard  2039:       fu=(*func)(u); 
                   2040:       if (fu < *fc) { 
1.183     brouard  2041: #ifdef DEBUG
1.224     brouard  2042:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2043:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2044: #endif
                   2045:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2046:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2047: #ifdef DEBUG
                   2048:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2049: #endif
                   2050:       } 
1.162     brouard  2051:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2052: #ifdef DEBUG
1.224     brouard  2053:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2054:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2055: #endif
1.126     brouard  2056:       u=ulim; 
                   2057:       fu=(*func)(u); 
1.183     brouard  2058:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2059: #ifdef DEBUG
1.224     brouard  2060:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2061:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2062: #endif
1.126     brouard  2063:       u=(*cx)+GOLD*(*cx-*bx); 
                   2064:       fu=(*func)(u); 
1.224     brouard  2065: #ifdef DEBUG
                   2066:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2067:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2068: #endif
1.183     brouard  2069:     } /* end tests */
1.126     brouard  2070:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2071:     SHFT(*fa,*fb,*fc,fu) 
                   2072: #ifdef DEBUG
1.224     brouard  2073:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2074:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2075: #endif
                   2076:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2077: } 
                   2078: 
                   2079: /*************** linmin ************************/
1.162     brouard  2080: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2081: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2082: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2083: the value of func at the returned location p . This is actually all accomplished by calling the
                   2084: routines mnbrak and brent .*/
1.126     brouard  2085: int ncom; 
                   2086: double *pcom,*xicom;
                   2087: double (*nrfunc)(double []); 
                   2088:  
1.224     brouard  2089: #ifdef LINMINORIGINAL
1.126     brouard  2090: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2091: #else
                   2092: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2093: #endif
1.126     brouard  2094: { 
                   2095:   double brent(double ax, double bx, double cx, 
                   2096:               double (*f)(double), double tol, double *xmin); 
                   2097:   double f1dim(double x); 
                   2098:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2099:              double *fc, double (*func)(double)); 
                   2100:   int j; 
                   2101:   double xx,xmin,bx,ax; 
                   2102:   double fx,fb,fa;
1.187     brouard  2103: 
1.203     brouard  2104: #ifdef LINMINORIGINAL
                   2105: #else
                   2106:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2107: #endif
                   2108:   
1.126     brouard  2109:   ncom=n; 
                   2110:   pcom=vector(1,n); 
                   2111:   xicom=vector(1,n); 
                   2112:   nrfunc=func; 
                   2113:   for (j=1;j<=n;j++) { 
                   2114:     pcom[j]=p[j]; 
1.202     brouard  2115:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2116:   } 
1.187     brouard  2117: 
1.203     brouard  2118: #ifdef LINMINORIGINAL
                   2119:   xx=1.;
                   2120: #else
                   2121:   axs=0.0;
                   2122:   xxs=1.;
                   2123:   do{
                   2124:     xx= xxs;
                   2125: #endif
1.187     brouard  2126:     ax=0.;
                   2127:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2128:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2129:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2130:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2131:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2132:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2133:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2134: #ifdef LINMINORIGINAL
                   2135: #else
                   2136:     if (fx != fx){
1.224     brouard  2137:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2138:                        printf("|");
                   2139:                        fprintf(ficlog,"|");
1.203     brouard  2140: #ifdef DEBUGLINMIN
1.224     brouard  2141:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2142: #endif
                   2143:     }
1.224     brouard  2144:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2145: #endif
                   2146:   
1.191     brouard  2147: #ifdef DEBUGLINMIN
                   2148:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2149:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2150: #endif
1.224     brouard  2151: #ifdef LINMINORIGINAL
                   2152: #else
                   2153:        if(fb == fx){ /* Flat function in the direction */
                   2154:                xmin=xx;
                   2155:     *flat=1;
                   2156:        }else{
                   2157:     *flat=0;
                   2158: #endif
                   2159:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2160:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2161:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2162:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2163:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2164:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2165: #ifdef DEBUG
1.224     brouard  2166:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2167:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2168: #endif
                   2169: #ifdef LINMINORIGINAL
                   2170: #else
                   2171:                        }
1.126     brouard  2172: #endif
1.191     brouard  2173: #ifdef DEBUGLINMIN
                   2174:   printf("linmin end ");
1.202     brouard  2175:   fprintf(ficlog,"linmin end ");
1.191     brouard  2176: #endif
1.126     brouard  2177:   for (j=1;j<=n;j++) { 
1.203     brouard  2178: #ifdef LINMINORIGINAL
                   2179:     xi[j] *= xmin; 
                   2180: #else
                   2181: #ifdef DEBUGLINMIN
                   2182:     if(xxs <1.0)
                   2183:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2184: #endif
                   2185:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2186: #ifdef DEBUGLINMIN
                   2187:     if(xxs <1.0)
                   2188:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2189: #endif
                   2190: #endif
1.187     brouard  2191:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2192:   } 
1.191     brouard  2193: #ifdef DEBUGLINMIN
1.203     brouard  2194:   printf("\n");
1.191     brouard  2195:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2196:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2197:   for (j=1;j<=n;j++) { 
1.202     brouard  2198:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2199:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2200:     if(j % ncovmodel == 0){
1.191     brouard  2201:       printf("\n");
1.202     brouard  2202:       fprintf(ficlog,"\n");
                   2203:     }
1.191     brouard  2204:   }
1.203     brouard  2205: #else
1.191     brouard  2206: #endif
1.126     brouard  2207:   free_vector(xicom,1,n); 
                   2208:   free_vector(pcom,1,n); 
                   2209: } 
                   2210: 
                   2211: 
                   2212: /*************** powell ************************/
1.162     brouard  2213: /*
                   2214: Minimization of a function func of n variables. Input consists of an initial starting point
                   2215: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2216: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2217: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2218: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2219: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2220:  */
1.224     brouard  2221: #ifdef LINMINORIGINAL
                   2222: #else
                   2223:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2224:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2225: #endif
1.126     brouard  2226: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2227:            double (*func)(double [])) 
                   2228: { 
1.224     brouard  2229: #ifdef LINMINORIGINAL
                   2230:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2231:              double (*func)(double [])); 
1.224     brouard  2232: #else 
1.241     brouard  2233:  void linmin(double p[], double xi[], int n, double *fret,
                   2234:             double (*func)(double []),int *flat); 
1.224     brouard  2235: #endif
1.239     brouard  2236:  int i,ibig,j,jk,k; 
1.126     brouard  2237:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2238:   double directest;
1.126     brouard  2239:   double fp,fptt;
                   2240:   double *xits;
                   2241:   int niterf, itmp;
1.224     brouard  2242: #ifdef LINMINORIGINAL
                   2243: #else
                   2244: 
                   2245:   flatdir=ivector(1,n); 
                   2246:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2247: #endif
1.126     brouard  2248: 
                   2249:   pt=vector(1,n); 
                   2250:   ptt=vector(1,n); 
                   2251:   xit=vector(1,n); 
                   2252:   xits=vector(1,n); 
                   2253:   *fret=(*func)(p); 
                   2254:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2255:   rcurr_time = time(NULL);  
1.126     brouard  2256:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2257:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2258:     ibig=0; 
                   2259:     del=0.0; 
1.157     brouard  2260:     rlast_time=rcurr_time;
                   2261:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2262:     rcurr_time = time(NULL);  
                   2263:     curr_time = *localtime(&rcurr_time);
                   2264:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2265:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2266: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2267:     for (i=1;i<=n;i++) {
1.126     brouard  2268:       fprintf(ficrespow," %.12lf", p[i]);
                   2269:     }
1.239     brouard  2270:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2271:     printf("\n#model=  1      +     age ");
                   2272:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2273:     if(nagesqr==1){
1.241     brouard  2274:        printf("  + age*age  ");
                   2275:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2276:     }
                   2277:     for(j=1;j <=ncovmodel-2;j++){
                   2278:       if(Typevar[j]==0) {
                   2279:        printf("  +      V%d  ",Tvar[j]);
                   2280:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2281:       }else if(Typevar[j]==1) {
                   2282:        printf("  +    V%d*age ",Tvar[j]);
                   2283:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2284:       }else if(Typevar[j]==2) {
                   2285:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2286:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2287:       }
                   2288:     }
1.126     brouard  2289:     printf("\n");
1.239     brouard  2290: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2291: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2292:     fprintf(ficlog,"\n");
1.239     brouard  2293:     for(i=1,jk=1; i <=nlstate; i++){
                   2294:       for(k=1; k <=(nlstate+ndeath); k++){
                   2295:        if (k != i) {
                   2296:          printf("%d%d ",i,k);
                   2297:          fprintf(ficlog,"%d%d ",i,k);
                   2298:          for(j=1; j <=ncovmodel; j++){
                   2299:            printf("%12.7f ",p[jk]);
                   2300:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2301:            jk++; 
                   2302:          }
                   2303:          printf("\n");
                   2304:          fprintf(ficlog,"\n");
                   2305:        }
                   2306:       }
                   2307:     }
1.241     brouard  2308:     if(*iter <=3 && *iter >1){
1.157     brouard  2309:       tml = *localtime(&rcurr_time);
                   2310:       strcpy(strcurr,asctime(&tml));
                   2311:       rforecast_time=rcurr_time; 
1.126     brouard  2312:       itmp = strlen(strcurr);
                   2313:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2314:        strcurr[itmp-1]='\0';
1.162     brouard  2315:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2316:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2317:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2318:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2319:        forecast_time = *localtime(&rforecast_time);
                   2320:        strcpy(strfor,asctime(&forecast_time));
                   2321:        itmp = strlen(strfor);
                   2322:        if(strfor[itmp-1]=='\n')
                   2323:          strfor[itmp-1]='\0';
                   2324:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2325:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2326:       }
                   2327:     }
1.187     brouard  2328:     for (i=1;i<=n;i++) { /* For each direction i */
                   2329:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2330:       fptt=(*fret); 
                   2331: #ifdef DEBUG
1.203     brouard  2332:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2333:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2334: #endif
1.203     brouard  2335:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2336:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2337: #ifdef LINMINORIGINAL
1.188     brouard  2338:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2339: #else
                   2340:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2341:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2342: #endif
                   2343:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2344:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2345:                                /* because that direction will be replaced unless the gain del is small */
                   2346:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2347:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2348:                                /* with the new direction. */
                   2349:                                del=fabs(fptt-(*fret)); 
                   2350:                                ibig=i; 
1.126     brouard  2351:       } 
                   2352: #ifdef DEBUG
                   2353:       printf("%d %.12e",i,(*fret));
                   2354:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2355:       for (j=1;j<=n;j++) {
1.224     brouard  2356:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2357:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2358:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2359:       }
                   2360:       for(j=1;j<=n;j++) {
1.225     brouard  2361:                                printf(" p(%d)=%.12e",j,p[j]);
                   2362:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2363:       }
                   2364:       printf("\n");
                   2365:       fprintf(ficlog,"\n");
                   2366: #endif
1.187     brouard  2367:     } /* end loop on each direction i */
                   2368:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2369:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2370:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2371:       for(j=1;j<=n;j++) {
1.225     brouard  2372:                                if(flatdir[j] >0){
                   2373:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2374:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2375:                                }
                   2376:                                /* printf("\n"); */
                   2377:                                /* fprintf(ficlog,"\n"); */
                   2378:                        }
1.243     brouard  2379:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2380:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2381:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2382:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2383:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2384:       /* decreased of more than 3.84  */
                   2385:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2386:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2387:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2388:                        
1.188     brouard  2389:       /* Starting the program with initial values given by a former maximization will simply change */
                   2390:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2391:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2392:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2393: #ifdef DEBUG
                   2394:       int k[2],l;
                   2395:       k[0]=1;
                   2396:       k[1]=-1;
                   2397:       printf("Max: %.12e",(*func)(p));
                   2398:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2399:       for (j=1;j<=n;j++) {
                   2400:        printf(" %.12e",p[j]);
                   2401:        fprintf(ficlog," %.12e",p[j]);
                   2402:       }
                   2403:       printf("\n");
                   2404:       fprintf(ficlog,"\n");
                   2405:       for(l=0;l<=1;l++) {
                   2406:        for (j=1;j<=n;j++) {
                   2407:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2408:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2409:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2410:        }
                   2411:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2412:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2413:       }
                   2414: #endif
                   2415: 
1.224     brouard  2416: #ifdef LINMINORIGINAL
                   2417: #else
                   2418:       free_ivector(flatdir,1,n); 
                   2419: #endif
1.126     brouard  2420:       free_vector(xit,1,n); 
                   2421:       free_vector(xits,1,n); 
                   2422:       free_vector(ptt,1,n); 
                   2423:       free_vector(pt,1,n); 
                   2424:       return; 
1.192     brouard  2425:     } /* enough precision */ 
1.240     brouard  2426:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2427:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2428:       ptt[j]=2.0*p[j]-pt[j]; 
                   2429:       xit[j]=p[j]-pt[j]; 
                   2430:       pt[j]=p[j]; 
                   2431:     } 
1.181     brouard  2432:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2433: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2434:                if (*iter <=4) {
1.225     brouard  2435: #else
                   2436: #endif
1.224     brouard  2437: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2438: #else
1.161     brouard  2439:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2440: #endif
1.162     brouard  2441:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2442:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2443:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2444:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2445:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2446:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2447:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2448:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2449:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2450:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2451:       /* mu² and del² are equal when f3=f1 */
                   2452:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2453:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2454:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2455:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2456: #ifdef NRCORIGINAL
                   2457:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2458: #else
                   2459:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2460:       t= t- del*SQR(fp-fptt);
1.183     brouard  2461: #endif
1.202     brouard  2462:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2463: #ifdef DEBUG
1.181     brouard  2464:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2465:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2466:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2467:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2468:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2469:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2470:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2471:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2472: #endif
1.183     brouard  2473: #ifdef POWELLORIGINAL
                   2474:       if (t < 0.0) { /* Then we use it for new direction */
                   2475: #else
1.182     brouard  2476:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2477:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2478:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2479:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2480:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2481:       } 
1.181     brouard  2482:       if (directest < 0.0) { /* Then we use it for new direction */
                   2483: #endif
1.191     brouard  2484: #ifdef DEBUGLINMIN
1.234     brouard  2485:        printf("Before linmin in direction P%d-P0\n",n);
                   2486:        for (j=1;j<=n;j++) {
                   2487:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2488:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2489:          if(j % ncovmodel == 0){
                   2490:            printf("\n");
                   2491:            fprintf(ficlog,"\n");
                   2492:          }
                   2493:        }
1.224     brouard  2494: #endif
                   2495: #ifdef LINMINORIGINAL
1.234     brouard  2496:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2497: #else
1.234     brouard  2498:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2499:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2500: #endif
1.234     brouard  2501:        
1.191     brouard  2502: #ifdef DEBUGLINMIN
1.234     brouard  2503:        for (j=1;j<=n;j++) { 
                   2504:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2505:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2506:          if(j % ncovmodel == 0){
                   2507:            printf("\n");
                   2508:            fprintf(ficlog,"\n");
                   2509:          }
                   2510:        }
1.224     brouard  2511: #endif
1.234     brouard  2512:        for (j=1;j<=n;j++) { 
                   2513:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2514:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2515:        }
1.224     brouard  2516: #ifdef LINMINORIGINAL
                   2517: #else
1.234     brouard  2518:        for (j=1, flatd=0;j<=n;j++) {
                   2519:          if(flatdir[j]>0)
                   2520:            flatd++;
                   2521:        }
                   2522:        if(flatd >0){
1.255     brouard  2523:          printf("%d flat directions: ",flatd);
                   2524:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2525:          for (j=1;j<=n;j++) { 
                   2526:            if(flatdir[j]>0){
                   2527:              printf("%d ",j);
                   2528:              fprintf(ficlog,"%d ",j);
                   2529:            }
                   2530:          }
                   2531:          printf("\n");
                   2532:          fprintf(ficlog,"\n");
                   2533:        }
1.191     brouard  2534: #endif
1.234     brouard  2535:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2536:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2537:        
1.126     brouard  2538: #ifdef DEBUG
1.234     brouard  2539:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2540:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2541:        for(j=1;j<=n;j++){
                   2542:          printf(" %lf",xit[j]);
                   2543:          fprintf(ficlog," %lf",xit[j]);
                   2544:        }
                   2545:        printf("\n");
                   2546:        fprintf(ficlog,"\n");
1.126     brouard  2547: #endif
1.192     brouard  2548:       } /* end of t or directest negative */
1.224     brouard  2549: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2550: #else
1.234     brouard  2551:       } /* end if (fptt < fp)  */
1.192     brouard  2552: #endif
1.225     brouard  2553: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2554:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2555: #else
1.224     brouard  2556: #endif
1.234     brouard  2557:                } /* loop iteration */ 
1.126     brouard  2558: } 
1.234     brouard  2559:   
1.126     brouard  2560: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2561:   
1.235     brouard  2562:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2563:   {
1.279     brouard  2564:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2565:      *   (and selected quantitative values in nres)
                   2566:      *  by left multiplying the unit
                   2567:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2568:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2569:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2570:      * or prevalence in state 1, prevalence in state 2, 0
                   2571:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2572:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2573:      * Output is prlim.
                   2574:      * Initial matrix pimij 
                   2575:      */
1.206     brouard  2576:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2577:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2578:   /*  0,                   0                  , 1} */
                   2579:   /*
                   2580:    * and after some iteration: */
                   2581:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2582:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2583:   /*  0,                   0                  , 1} */
                   2584:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2585:   /* {0.51571254859325999, 0.4842874514067399, */
                   2586:   /*  0.51326036147820708, 0.48673963852179264} */
                   2587:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2588:     
1.126     brouard  2589:   int i, ii,j,k;
1.209     brouard  2590:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2591:   /* double **matprod2(); */ /* test */
1.218     brouard  2592:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2593:   double **newm;
1.209     brouard  2594:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2595:   int ncvloop=0;
1.288     brouard  2596:   int first=0;
1.169     brouard  2597:   
1.209     brouard  2598:   min=vector(1,nlstate);
                   2599:   max=vector(1,nlstate);
                   2600:   meandiff=vector(1,nlstate);
                   2601: 
1.218     brouard  2602:        /* Starting with matrix unity */
1.126     brouard  2603:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2604:     for (j=1;j<=nlstate+ndeath;j++){
                   2605:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2606:     }
1.169     brouard  2607:   
                   2608:   cov[1]=1.;
                   2609:   
                   2610:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2611:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2612:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2613:     ncvloop++;
1.126     brouard  2614:     newm=savm;
                   2615:     /* Covariates have to be included here again */
1.138     brouard  2616:     cov[2]=agefin;
1.187     brouard  2617:     if(nagesqr==1)
                   2618:       cov[3]= agefin*agefin;;
1.234     brouard  2619:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2620:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2621:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2622:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2623:     }
                   2624:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2625:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2626:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2627:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2628:     }
1.237     brouard  2629:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2630:       if(Dummy[Tvar[Tage[k]]]){
                   2631:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2632:       } else{
1.235     brouard  2633:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2634:       }
1.235     brouard  2635:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2636:     }
1.237     brouard  2637:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2638:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2639:       if(Dummy[Tvard[k][1]==0]){
                   2640:        if(Dummy[Tvard[k][2]==0]){
                   2641:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2642:        }else{
                   2643:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2644:        }
                   2645:       }else{
                   2646:        if(Dummy[Tvard[k][2]==0]){
                   2647:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2648:        }else{
                   2649:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2650:        }
                   2651:       }
1.234     brouard  2652:     }
1.138     brouard  2653:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2654:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2655:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2656:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2657:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2658:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2659:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2660:     
1.126     brouard  2661:     savm=oldm;
                   2662:     oldm=newm;
1.209     brouard  2663: 
                   2664:     for(j=1; j<=nlstate; j++){
                   2665:       max[j]=0.;
                   2666:       min[j]=1.;
                   2667:     }
                   2668:     for(i=1;i<=nlstate;i++){
                   2669:       sumnew=0;
                   2670:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2671:       for(j=1; j<=nlstate; j++){ 
                   2672:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2673:        max[j]=FMAX(max[j],prlim[i][j]);
                   2674:        min[j]=FMIN(min[j],prlim[i][j]);
                   2675:       }
                   2676:     }
                   2677: 
1.126     brouard  2678:     maxmax=0.;
1.209     brouard  2679:     for(j=1; j<=nlstate; j++){
                   2680:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2681:       maxmax=FMAX(maxmax,meandiff[j]);
                   2682:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2683:     } /* j loop */
1.203     brouard  2684:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2685:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2686:     if(maxmax < ftolpl){
1.209     brouard  2687:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2688:       free_vector(min,1,nlstate);
                   2689:       free_vector(max,1,nlstate);
                   2690:       free_vector(meandiff,1,nlstate);
1.126     brouard  2691:       return prlim;
                   2692:     }
1.288     brouard  2693:   } /* agefin loop */
1.208     brouard  2694:     /* After some age loop it doesn't converge */
1.288     brouard  2695:   if(!first){
                   2696:     first=1;
                   2697:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2698:   }
                   2699:   fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2700: 
1.209     brouard  2701:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2702:   free_vector(min,1,nlstate);
                   2703:   free_vector(max,1,nlstate);
                   2704:   free_vector(meandiff,1,nlstate);
1.208     brouard  2705:   
1.169     brouard  2706:   return prlim; /* should not reach here */
1.126     brouard  2707: }
                   2708: 
1.217     brouard  2709: 
                   2710:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2711: 
1.218     brouard  2712:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2713:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2714:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2715: {
1.264     brouard  2716:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2717:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2718:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2719:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2720:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2721:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2722:   /* Initial matrix pimij */
                   2723:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2724:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2725:   /*  0,                   0                  , 1} */
                   2726:   /*
                   2727:    * and after some iteration: */
                   2728:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2729:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2730:   /*  0,                   0                  , 1} */
                   2731:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2732:   /* {0.51571254859325999, 0.4842874514067399, */
                   2733:   /*  0.51326036147820708, 0.48673963852179264} */
                   2734:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2735: 
                   2736:   int i, ii,j,k;
1.247     brouard  2737:   int first=0;
1.217     brouard  2738:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2739:   /* double **matprod2(); */ /* test */
                   2740:   double **out, cov[NCOVMAX+1], **bmij();
                   2741:   double **newm;
1.218     brouard  2742:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2743:   double        **oldm, **savm;  /* for use */
                   2744: 
1.217     brouard  2745:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2746:   int ncvloop=0;
                   2747:   
                   2748:   min=vector(1,nlstate);
                   2749:   max=vector(1,nlstate);
                   2750:   meandiff=vector(1,nlstate);
                   2751: 
1.266     brouard  2752:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2753:   oldm=oldms; savm=savms;
                   2754:   
                   2755:   /* Starting with matrix unity */
                   2756:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2757:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2758:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2759:     }
                   2760:   
                   2761:   cov[1]=1.;
                   2762:   
                   2763:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2764:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2765:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2766:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2767:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2768:     ncvloop++;
1.218     brouard  2769:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2770:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2771:     /* Covariates have to be included here again */
                   2772:     cov[2]=agefin;
                   2773:     if(nagesqr==1)
                   2774:       cov[3]= agefin*agefin;;
1.242     brouard  2775:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2776:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2777:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2778:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2779:     }
                   2780:     /* for (k=1; k<=cptcovn;k++) { */
                   2781:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2782:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2783:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2784:     /* } */
                   2785:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2786:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2787:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2788:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2789:     }
                   2790:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2791:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2792:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2793:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2794:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2795:       if(Dummy[Tvar[Tage[k]]]){
                   2796:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2797:       } else{
                   2798:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2799:       }
                   2800:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2801:     }
                   2802:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2803:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2804:       if(Dummy[Tvard[k][1]==0]){
                   2805:        if(Dummy[Tvard[k][2]==0]){
                   2806:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2807:        }else{
                   2808:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2809:        }
                   2810:       }else{
                   2811:        if(Dummy[Tvard[k][2]==0]){
                   2812:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2813:        }else{
                   2814:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2815:        }
                   2816:       }
1.217     brouard  2817:     }
                   2818:     
                   2819:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2820:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2821:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2822:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2823:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2824:                /* ij should be linked to the correct index of cov */
                   2825:                /* age and covariate values ij are in 'cov', but we need to pass
                   2826:                 * ij for the observed prevalence at age and status and covariate
                   2827:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2828:                 */
                   2829:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2830:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2831:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2832:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2833:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2834:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2835:     /*         printf("%d newm= ",i); */
                   2836:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2837:     /*           printf("%f ",newm[i][j]); */
                   2838:     /*         } */
                   2839:     /*         printf("oldm * "); */
                   2840:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2841:     /*           printf("%f ",oldm[i][j]); */
                   2842:     /*         } */
1.268     brouard  2843:     /*         printf(" bmmij "); */
1.266     brouard  2844:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2845:     /*           printf("%f ",pmmij[i][j]); */
                   2846:     /*         } */
                   2847:     /*         printf("\n"); */
                   2848:     /*   } */
                   2849:     /* } */
1.217     brouard  2850:     savm=oldm;
                   2851:     oldm=newm;
1.266     brouard  2852: 
1.217     brouard  2853:     for(j=1; j<=nlstate; j++){
                   2854:       max[j]=0.;
                   2855:       min[j]=1.;
                   2856:     }
                   2857:     for(j=1; j<=nlstate; j++){ 
                   2858:       for(i=1;i<=nlstate;i++){
1.234     brouard  2859:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2860:        bprlim[i][j]= newm[i][j];
                   2861:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2862:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2863:       }
                   2864:     }
1.218     brouard  2865:                
1.217     brouard  2866:     maxmax=0.;
                   2867:     for(i=1; i<=nlstate; i++){
                   2868:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2869:       maxmax=FMAX(maxmax,meandiff[i]);
                   2870:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2871:     } /* i loop */
1.217     brouard  2872:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2873:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2874:     if(maxmax < ftolpl){
1.220     brouard  2875:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2876:       free_vector(min,1,nlstate);
                   2877:       free_vector(max,1,nlstate);
                   2878:       free_vector(meandiff,1,nlstate);
                   2879:       return bprlim;
                   2880:     }
1.288     brouard  2881:   } /* agefin loop */
1.217     brouard  2882:     /* After some age loop it doesn't converge */
1.288     brouard  2883:   if(!first){
1.247     brouard  2884:     first=1;
                   2885:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2886: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2887:   }
                   2888:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2889: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2890:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2891:   free_vector(min,1,nlstate);
                   2892:   free_vector(max,1,nlstate);
                   2893:   free_vector(meandiff,1,nlstate);
                   2894:   
                   2895:   return bprlim; /* should not reach here */
                   2896: }
                   2897: 
1.126     brouard  2898: /*************** transition probabilities ***************/ 
                   2899: 
                   2900: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2901: {
1.138     brouard  2902:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2903:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2904:      model to the ncovmodel covariates (including constant and age).
                   2905:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2906:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2907:      ncth covariate in the global vector x is given by the formula:
                   2908:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2909:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2910:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2911:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2912:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2913:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2914:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2915:   */
                   2916:   double s1, lnpijopii;
1.126     brouard  2917:   /*double t34;*/
1.164     brouard  2918:   int i,j, nc, ii, jj;
1.126     brouard  2919: 
1.223     brouard  2920:   for(i=1; i<= nlstate; i++){
                   2921:     for(j=1; j<i;j++){
                   2922:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2923:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2924:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2925:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2926:       }
                   2927:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2928:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2929:     }
                   2930:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2931:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2932:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2933:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2934:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2935:       }
                   2936:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2937:     }
                   2938:   }
1.218     brouard  2939:   
1.223     brouard  2940:   for(i=1; i<= nlstate; i++){
                   2941:     s1=0;
                   2942:     for(j=1; j<i; j++){
                   2943:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2944:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2945:     }
                   2946:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2947:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2948:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2949:     }
                   2950:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2951:     ps[i][i]=1./(s1+1.);
                   2952:     /* Computing other pijs */
                   2953:     for(j=1; j<i; j++)
                   2954:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2955:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2956:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2957:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2958:   } /* end i */
1.218     brouard  2959:   
1.223     brouard  2960:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2961:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2962:       ps[ii][jj]=0;
                   2963:       ps[ii][ii]=1;
                   2964:     }
                   2965:   }
1.218     brouard  2966:   
                   2967:   
1.223     brouard  2968:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2969:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2970:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2971:   /*   } */
                   2972:   /*   printf("\n "); */
                   2973:   /* } */
                   2974:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2975:   /*
                   2976:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2977:                goto end;*/
1.266     brouard  2978:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2979: }
                   2980: 
1.218     brouard  2981: /*************** backward transition probabilities ***************/ 
                   2982: 
                   2983:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2984: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2985:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2986: {
1.266     brouard  2987:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2988:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2989:    */
1.218     brouard  2990:   int i, ii, j,k;
1.222     brouard  2991:   
                   2992:   double **out, **pmij();
                   2993:   double sumnew=0.;
1.218     brouard  2994:   double agefin;
1.292   ! brouard  2995:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  2996:   double **dnewm, **dsavm, **doldm;
                   2997:   double **bbmij;
                   2998:   
1.218     brouard  2999:   doldm=ddoldms; /* global pointers */
1.222     brouard  3000:   dnewm=ddnewms;
                   3001:   dsavm=ddsavms;
                   3002:   
                   3003:   agefin=cov[2];
1.268     brouard  3004:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3005:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3006:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3007:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3008: 
                   3009:   /* P_x */
1.266     brouard  3010:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3011:   /* outputs pmmij which is a stochastic matrix in row */
                   3012: 
                   3013:   /* Diag(w_x) */
1.292   ! brouard  3014:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3015:   sumnew=0.;
1.269     brouard  3016:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3017:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  3018:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  3019:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3020:   }
                   3021:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3022:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3023:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3024:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3025:     }
                   3026:   }else{
                   3027:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3028:       for (j=1;j<=nlstate+ndeath;j++)
                   3029:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3030:     }
                   3031:     /* if(sumnew <0.9){ */
                   3032:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3033:     /* } */
                   3034:   }
                   3035:   k3=0.0;  /* We put the last diagonal to 0 */
                   3036:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3037:       doldm[ii][ii]= k3;
                   3038:   }
                   3039:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3040:   
1.292   ! brouard  3041:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
        !          3042:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3043: 
1.292   ! brouard  3044:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3045:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3046:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3047:     sumnew=0.;
1.222     brouard  3048:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3049:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3050:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3051:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3052:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3053:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3054:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3055:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3056:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3057:        /* }else */
1.268     brouard  3058:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3059:     } /*End ii */
                   3060:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3061: 
1.292   ! brouard  3062:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3063:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3064:   /* end bmij */
1.266     brouard  3065:   return ps; /*pointer is unchanged */
1.218     brouard  3066: }
1.217     brouard  3067: /*************** transition probabilities ***************/ 
                   3068: 
1.218     brouard  3069: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3070: {
                   3071:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3072:      computes the probability to be observed in state j being in state i by appying the
                   3073:      model to the ncovmodel covariates (including constant and age).
                   3074:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3075:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3076:      ncth covariate in the global vector x is given by the formula:
                   3077:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3078:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3079:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3080:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3081:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3082:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3083:   */
                   3084:   double s1, lnpijopii;
                   3085:   /*double t34;*/
                   3086:   int i,j, nc, ii, jj;
                   3087: 
1.234     brouard  3088:   for(i=1; i<= nlstate; i++){
                   3089:     for(j=1; j<i;j++){
                   3090:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3091:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3092:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3093:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3094:       }
                   3095:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3096:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3097:     }
                   3098:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3099:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3100:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3101:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3102:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3103:       }
                   3104:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3105:     }
                   3106:   }
                   3107:   
                   3108:   for(i=1; i<= nlstate; i++){
                   3109:     s1=0;
                   3110:     for(j=1; j<i; j++){
                   3111:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3112:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3113:     }
                   3114:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3115:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3116:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3117:     }
                   3118:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3119:     ps[i][i]=1./(s1+1.);
                   3120:     /* Computing other pijs */
                   3121:     for(j=1; j<i; j++)
                   3122:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3123:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3124:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3125:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3126:   } /* end i */
                   3127:   
                   3128:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3129:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3130:       ps[ii][jj]=0;
                   3131:       ps[ii][ii]=1;
                   3132:     }
                   3133:   }
                   3134:   /* Added for backcast */ /* Transposed matrix too */
                   3135:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3136:     s1=0.;
                   3137:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3138:       s1+=ps[ii][jj];
                   3139:     }
                   3140:     for(ii=1; ii<= nlstate; ii++){
                   3141:       ps[ii][jj]=ps[ii][jj]/s1;
                   3142:     }
                   3143:   }
                   3144:   /* Transposition */
                   3145:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3146:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3147:       s1=ps[ii][jj];
                   3148:       ps[ii][jj]=ps[jj][ii];
                   3149:       ps[jj][ii]=s1;
                   3150:     }
                   3151:   }
                   3152:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3153:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3154:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3155:   /*   } */
                   3156:   /*   printf("\n "); */
                   3157:   /* } */
                   3158:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3159:   /*
                   3160:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3161:     goto end;*/
                   3162:   return ps;
1.217     brouard  3163: }
                   3164: 
                   3165: 
1.126     brouard  3166: /**************** Product of 2 matrices ******************/
                   3167: 
1.145     brouard  3168: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3169: {
                   3170:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3171:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3172:   /* in, b, out are matrice of pointers which should have been initialized 
                   3173:      before: only the contents of out is modified. The function returns
                   3174:      a pointer to pointers identical to out */
1.145     brouard  3175:   int i, j, k;
1.126     brouard  3176:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3177:     for(k=ncolol; k<=ncoloh; k++){
                   3178:       out[i][k]=0.;
                   3179:       for(j=ncl; j<=nch; j++)
                   3180:        out[i][k] +=in[i][j]*b[j][k];
                   3181:     }
1.126     brouard  3182:   return out;
                   3183: }
                   3184: 
                   3185: 
                   3186: /************* Higher Matrix Product ***************/
                   3187: 
1.235     brouard  3188: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3189: {
1.218     brouard  3190:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3191:      'nhstepm*hstepm*stepm' months (i.e. until
                   3192:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3193:      nhstepm*hstepm matrices. 
                   3194:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3195:      (typically every 2 years instead of every month which is too big 
                   3196:      for the memory).
                   3197:      Model is determined by parameters x and covariates have to be 
                   3198:      included manually here. 
                   3199: 
                   3200:      */
                   3201: 
                   3202:   int i, j, d, h, k;
1.131     brouard  3203:   double **out, cov[NCOVMAX+1];
1.126     brouard  3204:   double **newm;
1.187     brouard  3205:   double agexact;
1.214     brouard  3206:   double agebegin, ageend;
1.126     brouard  3207: 
                   3208:   /* Hstepm could be zero and should return the unit matrix */
                   3209:   for (i=1;i<=nlstate+ndeath;i++)
                   3210:     for (j=1;j<=nlstate+ndeath;j++){
                   3211:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3212:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3213:     }
                   3214:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3215:   for(h=1; h <=nhstepm; h++){
                   3216:     for(d=1; d <=hstepm; d++){
                   3217:       newm=savm;
                   3218:       /* Covariates have to be included here again */
                   3219:       cov[1]=1.;
1.214     brouard  3220:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3221:       cov[2]=agexact;
                   3222:       if(nagesqr==1)
1.227     brouard  3223:        cov[3]= agexact*agexact;
1.235     brouard  3224:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3225:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3226:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3227:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3228:       }
                   3229:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3230:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3231:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3232:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3233:       }
                   3234:       for (k=1; k<=cptcovage;k++){
                   3235:        if(Dummy[Tvar[Tage[k]]]){
                   3236:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3237:        } else{
                   3238:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3239:        }
                   3240:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3241:       }
                   3242:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3243:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3244:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3245:       }
                   3246:       /* for (k=1; k<=cptcovn;k++)  */
                   3247:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3248:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3249:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3250:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3251:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3252:       
                   3253:       
1.126     brouard  3254:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3255:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3256:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3257:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3258:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3259:       /* if((int)age == 70){ */
                   3260:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3261:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3262:       /*         printf("%d pmmij ",i); */
                   3263:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3264:       /*           printf("%f ",pmmij[i][j]); */
                   3265:       /*         } */
                   3266:       /*         printf(" oldm "); */
                   3267:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3268:       /*           printf("%f ",oldm[i][j]); */
                   3269:       /*         } */
                   3270:       /*         printf("\n"); */
                   3271:       /*       } */
                   3272:       /* } */
1.126     brouard  3273:       savm=oldm;
                   3274:       oldm=newm;
                   3275:     }
                   3276:     for(i=1; i<=nlstate+ndeath; i++)
                   3277:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3278:        po[i][j][h]=newm[i][j];
                   3279:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3280:       }
1.128     brouard  3281:     /*printf("h=%d ",h);*/
1.126     brouard  3282:   } /* end h */
1.267     brouard  3283:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3284:   return po;
                   3285: }
                   3286: 
1.217     brouard  3287: /************* Higher Back Matrix Product ***************/
1.218     brouard  3288: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3289: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3290: {
1.266     brouard  3291:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3292:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3293:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3294:      nhstepm*hstepm matrices.
                   3295:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3296:      (typically every 2 years instead of every month which is too big
1.217     brouard  3297:      for the memory).
1.218     brouard  3298:      Model is determined by parameters x and covariates have to be
1.266     brouard  3299:      included manually here. Then we use a call to bmij(x and cov)
                   3300:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3301:   */
1.217     brouard  3302: 
                   3303:   int i, j, d, h, k;
1.266     brouard  3304:   double **out, cov[NCOVMAX+1], **bmij();
                   3305:   double **newm, ***newmm;
1.217     brouard  3306:   double agexact;
                   3307:   double agebegin, ageend;
1.222     brouard  3308:   double **oldm, **savm;
1.217     brouard  3309: 
1.266     brouard  3310:   newmm=po; /* To be saved */
                   3311:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3312:   /* Hstepm could be zero and should return the unit matrix */
                   3313:   for (i=1;i<=nlstate+ndeath;i++)
                   3314:     for (j=1;j<=nlstate+ndeath;j++){
                   3315:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3316:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3317:     }
                   3318:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3319:   for(h=1; h <=nhstepm; h++){
                   3320:     for(d=1; d <=hstepm; d++){
                   3321:       newm=savm;
                   3322:       /* Covariates have to be included here again */
                   3323:       cov[1]=1.;
1.271     brouard  3324:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3325:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3326:       cov[2]=agexact;
                   3327:       if(nagesqr==1)
1.222     brouard  3328:        cov[3]= agexact*agexact;
1.266     brouard  3329:       for (k=1; k<=cptcovn;k++){
                   3330:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3331:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3332:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3333:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3334:       }
1.267     brouard  3335:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3336:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3337:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3338:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3339:       }
                   3340:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3341:        if(Dummy[Tvar[Tage[k]]]){
                   3342:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3343:        } else{
                   3344:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3345:        }
                   3346:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3347:       }
                   3348:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3349:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3350:       }                        
1.217     brouard  3351:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3352:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3353: 
1.218     brouard  3354:       /* Careful transposed matrix */
1.266     brouard  3355:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3356:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3357:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3358:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3359:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3360:       /* if((int)age == 70){ */
                   3361:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3362:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3363:       /*         printf("%d pmmij ",i); */
                   3364:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3365:       /*           printf("%f ",pmmij[i][j]); */
                   3366:       /*         } */
                   3367:       /*         printf(" oldm "); */
                   3368:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3369:       /*           printf("%f ",oldm[i][j]); */
                   3370:       /*         } */
                   3371:       /*         printf("\n"); */
                   3372:       /*       } */
                   3373:       /* } */
                   3374:       savm=oldm;
                   3375:       oldm=newm;
                   3376:     }
                   3377:     for(i=1; i<=nlstate+ndeath; i++)
                   3378:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3379:        po[i][j][h]=newm[i][j];
1.268     brouard  3380:        /* if(h==nhstepm) */
                   3381:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3382:       }
1.268     brouard  3383:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3384:   } /* end h */
1.268     brouard  3385:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3386:   return po;
                   3387: }
                   3388: 
                   3389: 
1.162     brouard  3390: #ifdef NLOPT
                   3391:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3392:   double fret;
                   3393:   double *xt;
                   3394:   int j;
                   3395:   myfunc_data *d2 = (myfunc_data *) pd;
                   3396: /* xt = (p1-1); */
                   3397:   xt=vector(1,n); 
                   3398:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3399: 
                   3400:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3401:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3402:   printf("Function = %.12lf ",fret);
                   3403:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3404:   printf("\n");
                   3405:  free_vector(xt,1,n);
                   3406:   return fret;
                   3407: }
                   3408: #endif
1.126     brouard  3409: 
                   3410: /*************** log-likelihood *************/
                   3411: double func( double *x)
                   3412: {
1.226     brouard  3413:   int i, ii, j, k, mi, d, kk;
                   3414:   int ioffset=0;
                   3415:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3416:   double **out;
                   3417:   double lli; /* Individual log likelihood */
                   3418:   int s1, s2;
1.228     brouard  3419:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3420:   double bbh, survp;
                   3421:   long ipmx;
                   3422:   double agexact;
                   3423:   /*extern weight */
                   3424:   /* We are differentiating ll according to initial status */
                   3425:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3426:   /*for(i=1;i<imx;i++) 
                   3427:     printf(" %d\n",s[4][i]);
                   3428:   */
1.162     brouard  3429: 
1.226     brouard  3430:   ++countcallfunc;
1.162     brouard  3431: 
1.226     brouard  3432:   cov[1]=1.;
1.126     brouard  3433: 
1.226     brouard  3434:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3435:   ioffset=0;
1.226     brouard  3436:   if(mle==1){
                   3437:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3438:       /* Computes the values of the ncovmodel covariates of the model
                   3439:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3440:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3441:         to be observed in j being in i according to the model.
                   3442:       */
1.243     brouard  3443:       ioffset=2+nagesqr ;
1.233     brouard  3444:    /* Fixed */
1.234     brouard  3445:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3446:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3447:       }
1.226     brouard  3448:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3449:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3450:         has been calculated etc */
                   3451:       /* For an individual i, wav[i] gives the number of effective waves */
                   3452:       /* We compute the contribution to Likelihood of each effective transition
                   3453:         mw[mi][i] is real wave of the mi th effectve wave */
                   3454:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3455:         s2=s[mw[mi+1][i]][i];
                   3456:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3457:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3458:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3459:       */
                   3460:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3461:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3462:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3463:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3464:        }
                   3465:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3466:          for (j=1;j<=nlstate+ndeath;j++){
                   3467:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3468:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3469:          }
                   3470:        for(d=0; d<dh[mi][i]; d++){
                   3471:          newm=savm;
                   3472:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3473:          cov[2]=agexact;
                   3474:          if(nagesqr==1)
                   3475:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3476:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3477:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3478:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3479:          else
                   3480:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3481:          }
                   3482:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3483:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3484:          savm=oldm;
                   3485:          oldm=newm;
                   3486:        } /* end mult */
                   3487:        
                   3488:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3489:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3490:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3491:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3492:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3493:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3494:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3495:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3496:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3497:                                 * -stepm/2 to stepm/2 .
                   3498:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3499:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3500:                                 */
1.234     brouard  3501:        s1=s[mw[mi][i]][i];
                   3502:        s2=s[mw[mi+1][i]][i];
                   3503:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3504:        /* bias bh is positive if real duration
                   3505:         * is higher than the multiple of stepm and negative otherwise.
                   3506:         */
                   3507:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3508:        if( s2 > nlstate){ 
                   3509:          /* i.e. if s2 is a death state and if the date of death is known 
                   3510:             then the contribution to the likelihood is the probability to 
                   3511:             die between last step unit time and current  step unit time, 
                   3512:             which is also equal to probability to die before dh 
                   3513:             minus probability to die before dh-stepm . 
                   3514:             In version up to 0.92 likelihood was computed
                   3515:             as if date of death was unknown. Death was treated as any other
                   3516:             health state: the date of the interview describes the actual state
                   3517:             and not the date of a change in health state. The former idea was
                   3518:             to consider that at each interview the state was recorded
                   3519:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3520:             introduced the exact date of death then we should have modified
                   3521:             the contribution of an exact death to the likelihood. This new
                   3522:             contribution is smaller and very dependent of the step unit
                   3523:             stepm. It is no more the probability to die between last interview
                   3524:             and month of death but the probability to survive from last
                   3525:             interview up to one month before death multiplied by the
                   3526:             probability to die within a month. Thanks to Chris
                   3527:             Jackson for correcting this bug.  Former versions increased
                   3528:             mortality artificially. The bad side is that we add another loop
                   3529:             which slows down the processing. The difference can be up to 10%
                   3530:             lower mortality.
                   3531:          */
                   3532:          /* If, at the beginning of the maximization mostly, the
                   3533:             cumulative probability or probability to be dead is
                   3534:             constant (ie = 1) over time d, the difference is equal to
                   3535:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3536:             s1 at precedent wave, to be dead a month before current
                   3537:             wave is equal to probability, being at state s1 at
                   3538:             precedent wave, to be dead at mont of the current
                   3539:             wave. Then the observed probability (that this person died)
                   3540:             is null according to current estimated parameter. In fact,
                   3541:             it should be very low but not zero otherwise the log go to
                   3542:             infinity.
                   3543:          */
1.183     brouard  3544: /* #ifdef INFINITYORIGINAL */
                   3545: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3546: /* #else */
                   3547: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3548: /*         lli=log(mytinydouble); */
                   3549: /*       else */
                   3550: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3551: /* #endif */
1.226     brouard  3552:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3553:          
1.226     brouard  3554:        } else if  ( s2==-1 ) { /* alive */
                   3555:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3556:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3557:          /*survp += out[s1][j]; */
                   3558:          lli= log(survp);
                   3559:        }
                   3560:        else if  (s2==-4) { 
                   3561:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3562:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3563:          lli= log(survp); 
                   3564:        } 
                   3565:        else if  (s2==-5) { 
                   3566:          for (j=1,survp=0. ; j<=2; j++)  
                   3567:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3568:          lli= log(survp); 
                   3569:        } 
                   3570:        else{
                   3571:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3572:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3573:        } 
                   3574:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3575:        /*if(lli ==000.0)*/
                   3576:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3577:        ipmx +=1;
                   3578:        sw += weight[i];
                   3579:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3580:        /* if (lli < log(mytinydouble)){ */
                   3581:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3582:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3583:        /* } */
                   3584:       } /* end of wave */
                   3585:     } /* end of individual */
                   3586:   }  else if(mle==2){
                   3587:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3588:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3589:       for(mi=1; mi<= wav[i]-1; mi++){
                   3590:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3591:          for (j=1;j<=nlstate+ndeath;j++){
                   3592:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3593:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3594:          }
                   3595:        for(d=0; d<=dh[mi][i]; d++){
                   3596:          newm=savm;
                   3597:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3598:          cov[2]=agexact;
                   3599:          if(nagesqr==1)
                   3600:            cov[3]= agexact*agexact;
                   3601:          for (kk=1; kk<=cptcovage;kk++) {
                   3602:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3603:          }
                   3604:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3605:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3606:          savm=oldm;
                   3607:          oldm=newm;
                   3608:        } /* end mult */
                   3609:       
                   3610:        s1=s[mw[mi][i]][i];
                   3611:        s2=s[mw[mi+1][i]][i];
                   3612:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3613:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3614:        ipmx +=1;
                   3615:        sw += weight[i];
                   3616:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3617:       } /* end of wave */
                   3618:     } /* end of individual */
                   3619:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3620:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3621:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3622:       for(mi=1; mi<= wav[i]-1; mi++){
                   3623:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3624:          for (j=1;j<=nlstate+ndeath;j++){
                   3625:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3626:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3627:          }
                   3628:        for(d=0; d<dh[mi][i]; d++){
                   3629:          newm=savm;
                   3630:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3631:          cov[2]=agexact;
                   3632:          if(nagesqr==1)
                   3633:            cov[3]= agexact*agexact;
                   3634:          for (kk=1; kk<=cptcovage;kk++) {
                   3635:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3636:          }
                   3637:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3638:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3639:          savm=oldm;
                   3640:          oldm=newm;
                   3641:        } /* end mult */
                   3642:       
                   3643:        s1=s[mw[mi][i]][i];
                   3644:        s2=s[mw[mi+1][i]][i];
                   3645:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3646:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3647:        ipmx +=1;
                   3648:        sw += weight[i];
                   3649:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3650:       } /* end of wave */
                   3651:     } /* end of individual */
                   3652:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3653:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3654:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3655:       for(mi=1; mi<= wav[i]-1; mi++){
                   3656:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3657:          for (j=1;j<=nlstate+ndeath;j++){
                   3658:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3659:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3660:          }
                   3661:        for(d=0; d<dh[mi][i]; d++){
                   3662:          newm=savm;
                   3663:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3664:          cov[2]=agexact;
                   3665:          if(nagesqr==1)
                   3666:            cov[3]= agexact*agexact;
                   3667:          for (kk=1; kk<=cptcovage;kk++) {
                   3668:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3669:          }
1.126     brouard  3670:        
1.226     brouard  3671:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3672:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3673:          savm=oldm;
                   3674:          oldm=newm;
                   3675:        } /* end mult */
                   3676:       
                   3677:        s1=s[mw[mi][i]][i];
                   3678:        s2=s[mw[mi+1][i]][i];
                   3679:        if( s2 > nlstate){ 
                   3680:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3681:        } else if  ( s2==-1 ) { /* alive */
                   3682:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3683:            survp += out[s1][j];
                   3684:          lli= log(survp);
                   3685:        }else{
                   3686:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3687:        }
                   3688:        ipmx +=1;
                   3689:        sw += weight[i];
                   3690:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3691: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3692:       } /* end of wave */
                   3693:     } /* end of individual */
                   3694:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3695:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3696:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3697:       for(mi=1; mi<= wav[i]-1; mi++){
                   3698:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3699:          for (j=1;j<=nlstate+ndeath;j++){
                   3700:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3701:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3702:          }
                   3703:        for(d=0; d<dh[mi][i]; d++){
                   3704:          newm=savm;
                   3705:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3706:          cov[2]=agexact;
                   3707:          if(nagesqr==1)
                   3708:            cov[3]= agexact*agexact;
                   3709:          for (kk=1; kk<=cptcovage;kk++) {
                   3710:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3711:          }
1.126     brouard  3712:        
1.226     brouard  3713:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3714:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3715:          savm=oldm;
                   3716:          oldm=newm;
                   3717:        } /* end mult */
                   3718:       
                   3719:        s1=s[mw[mi][i]][i];
                   3720:        s2=s[mw[mi+1][i]][i];
                   3721:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3722:        ipmx +=1;
                   3723:        sw += weight[i];
                   3724:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3725:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3726:       } /* end of wave */
                   3727:     } /* end of individual */
                   3728:   } /* End of if */
                   3729:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3730:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3731:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3732:   return -l;
1.126     brouard  3733: }
                   3734: 
                   3735: /*************** log-likelihood *************/
                   3736: double funcone( double *x)
                   3737: {
1.228     brouard  3738:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3739:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3740:   int ioffset=0;
1.131     brouard  3741:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3742:   double **out;
                   3743:   double lli; /* Individual log likelihood */
                   3744:   double llt;
                   3745:   int s1, s2;
1.228     brouard  3746:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3747: 
1.126     brouard  3748:   double bbh, survp;
1.187     brouard  3749:   double agexact;
1.214     brouard  3750:   double agebegin, ageend;
1.126     brouard  3751:   /*extern weight */
                   3752:   /* We are differentiating ll according to initial status */
                   3753:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3754:   /*for(i=1;i<imx;i++) 
                   3755:     printf(" %d\n",s[4][i]);
                   3756:   */
                   3757:   cov[1]=1.;
                   3758: 
                   3759:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3760:   ioffset=0;
                   3761:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3762:     /* ioffset=2+nagesqr+cptcovage; */
                   3763:     ioffset=2+nagesqr;
1.232     brouard  3764:     /* Fixed */
1.224     brouard  3765:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3766:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3767:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3768:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3769: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3770: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3771: /*    cov[2+6]=covar[2][i]; V2  */
                   3772: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3773: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3774: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3775: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3776: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3777: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3778:     }
1.232     brouard  3779:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3780:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3781:     /* } */
1.231     brouard  3782:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3783:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3784:     /* } */
1.225     brouard  3785:     
1.233     brouard  3786: 
                   3787:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3788:     /* Wave varying (but not age varying) */
                   3789:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3790:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3791:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3792:       }
1.232     brouard  3793:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3794:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3795:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3796:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3797:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3798:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3799:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3800:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3801:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3802:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3803:       /* } */
1.126     brouard  3804:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3805:        for (j=1;j<=nlstate+ndeath;j++){
                   3806:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3807:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3808:        }
1.214     brouard  3809:       
                   3810:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3811:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3812:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3813:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3814:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3815:          and mw[mi+1][i]. dh depends on stepm.*/
                   3816:        newm=savm;
1.247     brouard  3817:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3818:        cov[2]=agexact;
                   3819:        if(nagesqr==1)
                   3820:          cov[3]= agexact*agexact;
                   3821:        for (kk=1; kk<=cptcovage;kk++) {
                   3822:          if(!FixedV[Tvar[Tage[kk]]])
                   3823:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3824:          else
                   3825:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3826:        }
                   3827:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3828:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3829:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3830:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3831:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3832:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3833:        savm=oldm;
                   3834:        oldm=newm;
1.126     brouard  3835:       } /* end mult */
                   3836:       
                   3837:       s1=s[mw[mi][i]][i];
                   3838:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3839:       /* if(s2==-1){ */
1.268     brouard  3840:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3841:       /*       /\* exit(1); *\/ */
                   3842:       /* } */
1.126     brouard  3843:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3844:       /* bias is positive if real duration
                   3845:        * is higher than the multiple of stepm and negative otherwise.
                   3846:        */
                   3847:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3848:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3849:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3850:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3851:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3852:        lli= log(survp);
1.126     brouard  3853:       }else if (mle==1){
1.242     brouard  3854:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3855:       } else if(mle==2){
1.242     brouard  3856:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3857:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3858:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3859:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3860:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3861:       } else{  /* mle=0 back to 1 */
1.242     brouard  3862:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3863:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3864:       } /* End of if */
                   3865:       ipmx +=1;
                   3866:       sw += weight[i];
                   3867:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3868:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3869:       if(globpr){
1.246     brouard  3870:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3871:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3872:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3873:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3874:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3875:          llt +=ll[k]*gipmx/gsw;
                   3876:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3877:        }
                   3878:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3879:       }
1.232     brouard  3880:        } /* end of wave */
                   3881: } /* end of individual */
                   3882: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3883: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3884: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3885: if(globpr==0){ /* First time we count the contributions and weights */
                   3886:        gipmx=ipmx;
                   3887:        gsw=sw;
                   3888: }
                   3889: return -l;
1.126     brouard  3890: }
                   3891: 
                   3892: 
                   3893: /*************** function likelione ***********/
1.292   ! brouard  3894: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  3895: {
                   3896:   /* This routine should help understanding what is done with 
                   3897:      the selection of individuals/waves and
                   3898:      to check the exact contribution to the likelihood.
                   3899:      Plotting could be done.
                   3900:    */
                   3901:   int k;
                   3902: 
                   3903:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3904:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3905:     strcat(fileresilk,fileresu);
1.126     brouard  3906:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3907:       printf("Problem with resultfile: %s\n", fileresilk);
                   3908:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3909:     }
1.214     brouard  3910:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3911:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3912:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3913:     for(k=1; k<=nlstate; k++) 
                   3914:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3915:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3916:   }
                   3917: 
1.292   ! brouard  3918:   *fretone=(*func)(p);
1.126     brouard  3919:   if(*globpri !=0){
                   3920:     fclose(ficresilk);
1.205     brouard  3921:     if (mle ==0)
                   3922:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3923:     else if(mle >=1)
                   3924:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3925:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3926:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3927:       
                   3928:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3929:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3930: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3931:     }
1.207     brouard  3932:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3933: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3934:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3935: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3936:     fflush(fichtm);
1.205     brouard  3937:   }
1.126     brouard  3938:   return;
                   3939: }
                   3940: 
                   3941: 
                   3942: /*********** Maximum Likelihood Estimation ***************/
                   3943: 
                   3944: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3945: {
1.165     brouard  3946:   int i,j, iter=0;
1.126     brouard  3947:   double **xi;
                   3948:   double fret;
                   3949:   double fretone; /* Only one call to likelihood */
                   3950:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3951: 
                   3952: #ifdef NLOPT
                   3953:   int creturn;
                   3954:   nlopt_opt opt;
                   3955:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3956:   double *lb;
                   3957:   double minf; /* the minimum objective value, upon return */
                   3958:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3959:   myfunc_data dinst, *d = &dinst;
                   3960: #endif
                   3961: 
                   3962: 
1.126     brouard  3963:   xi=matrix(1,npar,1,npar);
                   3964:   for (i=1;i<=npar;i++)
                   3965:     for (j=1;j<=npar;j++)
                   3966:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3967:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3968:   strcpy(filerespow,"POW_"); 
1.126     brouard  3969:   strcat(filerespow,fileres);
                   3970:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3971:     printf("Problem with resultfile: %s\n", filerespow);
                   3972:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3973:   }
                   3974:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3975:   for (i=1;i<=nlstate;i++)
                   3976:     for(j=1;j<=nlstate+ndeath;j++)
                   3977:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3978:   fprintf(ficrespow,"\n");
1.162     brouard  3979: #ifdef POWELL
1.126     brouard  3980:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3981: #endif
1.126     brouard  3982: 
1.162     brouard  3983: #ifdef NLOPT
                   3984: #ifdef NEWUOA
                   3985:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3986: #else
                   3987:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3988: #endif
                   3989:   lb=vector(0,npar-1);
                   3990:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   3991:   nlopt_set_lower_bounds(opt, lb);
                   3992:   nlopt_set_initial_step1(opt, 0.1);
                   3993:   
                   3994:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   3995:   d->function = func;
                   3996:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   3997:   nlopt_set_min_objective(opt, myfunc, d);
                   3998:   nlopt_set_xtol_rel(opt, ftol);
                   3999:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4000:     printf("nlopt failed! %d\n",creturn); 
                   4001:   }
                   4002:   else {
                   4003:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4004:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4005:     iter=1; /* not equal */
                   4006:   }
                   4007:   nlopt_destroy(opt);
                   4008: #endif
1.126     brouard  4009:   free_matrix(xi,1,npar,1,npar);
                   4010:   fclose(ficrespow);
1.203     brouard  4011:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4012:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4013:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4014: 
                   4015: }
                   4016: 
                   4017: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4018: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4019: {
                   4020:   double  **a,**y,*x,pd;
1.203     brouard  4021:   /* double **hess; */
1.164     brouard  4022:   int i, j;
1.126     brouard  4023:   int *indx;
                   4024: 
                   4025:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4026:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4027:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4028:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4029:   double gompertz(double p[]);
1.203     brouard  4030:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4031: 
                   4032:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4033:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4034:   for (i=1;i<=npar;i++){
1.203     brouard  4035:     printf("%d-",i);fflush(stdout);
                   4036:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4037:    
                   4038:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4039:     
                   4040:     /*  printf(" %f ",p[i]);
                   4041:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4042:   }
                   4043:   
                   4044:   for (i=1;i<=npar;i++) {
                   4045:     for (j=1;j<=npar;j++)  {
                   4046:       if (j>i) { 
1.203     brouard  4047:        printf(".%d-%d",i,j);fflush(stdout);
                   4048:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4049:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4050:        
                   4051:        hess[j][i]=hess[i][j];    
                   4052:        /*printf(" %lf ",hess[i][j]);*/
                   4053:       }
                   4054:     }
                   4055:   }
                   4056:   printf("\n");
                   4057:   fprintf(ficlog,"\n");
                   4058: 
                   4059:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4060:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4061:   
                   4062:   a=matrix(1,npar,1,npar);
                   4063:   y=matrix(1,npar,1,npar);
                   4064:   x=vector(1,npar);
                   4065:   indx=ivector(1,npar);
                   4066:   for (i=1;i<=npar;i++)
                   4067:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4068:   ludcmp(a,npar,indx,&pd);
                   4069: 
                   4070:   for (j=1;j<=npar;j++) {
                   4071:     for (i=1;i<=npar;i++) x[i]=0;
                   4072:     x[j]=1;
                   4073:     lubksb(a,npar,indx,x);
                   4074:     for (i=1;i<=npar;i++){ 
                   4075:       matcov[i][j]=x[i];
                   4076:     }
                   4077:   }
                   4078: 
                   4079:   printf("\n#Hessian matrix#\n");
                   4080:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4081:   for (i=1;i<=npar;i++) { 
                   4082:     for (j=1;j<=npar;j++) { 
1.203     brouard  4083:       printf("%.6e ",hess[i][j]);
                   4084:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4085:     }
                   4086:     printf("\n");
                   4087:     fprintf(ficlog,"\n");
                   4088:   }
                   4089: 
1.203     brouard  4090:   /* printf("\n#Covariance matrix#\n"); */
                   4091:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4092:   /* for (i=1;i<=npar;i++) {  */
                   4093:   /*   for (j=1;j<=npar;j++) {  */
                   4094:   /*     printf("%.6e ",matcov[i][j]); */
                   4095:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4096:   /*   } */
                   4097:   /*   printf("\n"); */
                   4098:   /*   fprintf(ficlog,"\n"); */
                   4099:   /* } */
                   4100: 
1.126     brouard  4101:   /* Recompute Inverse */
1.203     brouard  4102:   /* for (i=1;i<=npar;i++) */
                   4103:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4104:   /* ludcmp(a,npar,indx,&pd); */
                   4105: 
                   4106:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4107: 
                   4108:   /* for (j=1;j<=npar;j++) { */
                   4109:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4110:   /*   x[j]=1; */
                   4111:   /*   lubksb(a,npar,indx,x); */
                   4112:   /*   for (i=1;i<=npar;i++){  */
                   4113:   /*     y[i][j]=x[i]; */
                   4114:   /*     printf("%.3e ",y[i][j]); */
                   4115:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4116:   /*   } */
                   4117:   /*   printf("\n"); */
                   4118:   /*   fprintf(ficlog,"\n"); */
                   4119:   /* } */
                   4120: 
                   4121:   /* Verifying the inverse matrix */
                   4122: #ifdef DEBUGHESS
                   4123:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4124: 
1.203     brouard  4125:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4126:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4127: 
                   4128:   for (j=1;j<=npar;j++) {
                   4129:     for (i=1;i<=npar;i++){ 
1.203     brouard  4130:       printf("%.2f ",y[i][j]);
                   4131:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4132:     }
                   4133:     printf("\n");
                   4134:     fprintf(ficlog,"\n");
                   4135:   }
1.203     brouard  4136: #endif
1.126     brouard  4137: 
                   4138:   free_matrix(a,1,npar,1,npar);
                   4139:   free_matrix(y,1,npar,1,npar);
                   4140:   free_vector(x,1,npar);
                   4141:   free_ivector(indx,1,npar);
1.203     brouard  4142:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4143: 
                   4144: 
                   4145: }
                   4146: 
                   4147: /*************** hessian matrix ****************/
                   4148: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4149: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4150:   int i;
                   4151:   int l=1, lmax=20;
1.203     brouard  4152:   double k1,k2, res, fx;
1.132     brouard  4153:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4154:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4155:   int k=0,kmax=10;
                   4156:   double l1;
                   4157: 
                   4158:   fx=func(x);
                   4159:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4160:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4161:     l1=pow(10,l);
                   4162:     delts=delt;
                   4163:     for(k=1 ; k <kmax; k=k+1){
                   4164:       delt = delta*(l1*k);
                   4165:       p2[theta]=x[theta] +delt;
1.145     brouard  4166:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4167:       p2[theta]=x[theta]-delt;
                   4168:       k2=func(p2)-fx;
                   4169:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4170:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4171:       
1.203     brouard  4172: #ifdef DEBUGHESSII
1.126     brouard  4173:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4174:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4175: #endif
                   4176:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4177:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4178:        k=kmax;
                   4179:       }
                   4180:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4181:        k=kmax; l=lmax*10;
1.126     brouard  4182:       }
                   4183:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4184:        delts=delt;
                   4185:       }
1.203     brouard  4186:     } /* End loop k */
1.126     brouard  4187:   }
                   4188:   delti[theta]=delts;
                   4189:   return res; 
                   4190:   
                   4191: }
                   4192: 
1.203     brouard  4193: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4194: {
                   4195:   int i;
1.164     brouard  4196:   int l=1, lmax=20;
1.126     brouard  4197:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4198:   double p2[MAXPARM+1];
1.203     brouard  4199:   int k, kmax=1;
                   4200:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4201: 
                   4202:   int firstime=0;
1.203     brouard  4203:   
1.126     brouard  4204:   fx=func(x);
1.203     brouard  4205:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4206:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4207:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4208:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4209:     k1=func(p2)-fx;
                   4210:   
1.203     brouard  4211:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4212:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4213:     k2=func(p2)-fx;
                   4214:   
1.203     brouard  4215:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4216:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4217:     k3=func(p2)-fx;
                   4218:   
1.203     brouard  4219:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4220:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4221:     k4=func(p2)-fx;
1.203     brouard  4222:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4223:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4224:       firstime=1;
1.203     brouard  4225:       kmax=kmax+10;
1.208     brouard  4226:     }
                   4227:     if(kmax >=10 || firstime ==1){
1.246     brouard  4228:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4229:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4230:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4231:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4232:     }
                   4233: #ifdef DEBUGHESSIJ
                   4234:     v1=hess[thetai][thetai];
                   4235:     v2=hess[thetaj][thetaj];
                   4236:     cv12=res;
                   4237:     /* Computing eigen value of Hessian matrix */
                   4238:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4239:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4240:     if ((lc2 <0) || (lc1 <0) ){
                   4241:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4242:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4243:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4244:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4245:     }
1.126     brouard  4246: #endif
                   4247:   }
                   4248:   return res;
                   4249: }
                   4250: 
1.203     brouard  4251:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4252: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4253: /* { */
                   4254: /*   int i; */
                   4255: /*   int l=1, lmax=20; */
                   4256: /*   double k1,k2,k3,k4,res,fx; */
                   4257: /*   double p2[MAXPARM+1]; */
                   4258: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4259: /*   int k=0,kmax=10; */
                   4260: /*   double l1; */
                   4261:   
                   4262: /*   fx=func(x); */
                   4263: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4264: /*     l1=pow(10,l); */
                   4265: /*     delts=delt; */
                   4266: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4267: /*       delt = delti*(l1*k); */
                   4268: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4269: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4270: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4271: /*       k1=func(p2)-fx; */
                   4272:       
                   4273: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4274: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4275: /*       k2=func(p2)-fx; */
                   4276:       
                   4277: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4278: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4279: /*       k3=func(p2)-fx; */
                   4280:       
                   4281: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4282: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4283: /*       k4=func(p2)-fx; */
                   4284: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4285: /* #ifdef DEBUGHESSIJ */
                   4286: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4287: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4288: /* #endif */
                   4289: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4290: /*     k=kmax; */
                   4291: /*       } */
                   4292: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4293: /*     k=kmax; l=lmax*10; */
                   4294: /*       } */
                   4295: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4296: /*     delts=delt; */
                   4297: /*       } */
                   4298: /*     } /\* End loop k *\/ */
                   4299: /*   } */
                   4300: /*   delti[theta]=delts; */
                   4301: /*   return res;  */
                   4302: /* } */
                   4303: 
                   4304: 
1.126     brouard  4305: /************** Inverse of matrix **************/
                   4306: void ludcmp(double **a, int n, int *indx, double *d) 
                   4307: { 
                   4308:   int i,imax,j,k; 
                   4309:   double big,dum,sum,temp; 
                   4310:   double *vv; 
                   4311:  
                   4312:   vv=vector(1,n); 
                   4313:   *d=1.0; 
                   4314:   for (i=1;i<=n;i++) { 
                   4315:     big=0.0; 
                   4316:     for (j=1;j<=n;j++) 
                   4317:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4318:     if (big == 0.0){
                   4319:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4320:       for (j=1;j<=n;j++) {
                   4321:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4322:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4323:       }
                   4324:       fflush(ficlog);
                   4325:       fclose(ficlog);
                   4326:       nrerror("Singular matrix in routine ludcmp"); 
                   4327:     }
1.126     brouard  4328:     vv[i]=1.0/big; 
                   4329:   } 
                   4330:   for (j=1;j<=n;j++) { 
                   4331:     for (i=1;i<j;i++) { 
                   4332:       sum=a[i][j]; 
                   4333:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4334:       a[i][j]=sum; 
                   4335:     } 
                   4336:     big=0.0; 
                   4337:     for (i=j;i<=n;i++) { 
                   4338:       sum=a[i][j]; 
                   4339:       for (k=1;k<j;k++) 
                   4340:        sum -= a[i][k]*a[k][j]; 
                   4341:       a[i][j]=sum; 
                   4342:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4343:        big=dum; 
                   4344:        imax=i; 
                   4345:       } 
                   4346:     } 
                   4347:     if (j != imax) { 
                   4348:       for (k=1;k<=n;k++) { 
                   4349:        dum=a[imax][k]; 
                   4350:        a[imax][k]=a[j][k]; 
                   4351:        a[j][k]=dum; 
                   4352:       } 
                   4353:       *d = -(*d); 
                   4354:       vv[imax]=vv[j]; 
                   4355:     } 
                   4356:     indx[j]=imax; 
                   4357:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4358:     if (j != n) { 
                   4359:       dum=1.0/(a[j][j]); 
                   4360:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4361:     } 
                   4362:   } 
                   4363:   free_vector(vv,1,n);  /* Doesn't work */
                   4364: ;
                   4365: } 
                   4366: 
                   4367: void lubksb(double **a, int n, int *indx, double b[]) 
                   4368: { 
                   4369:   int i,ii=0,ip,j; 
                   4370:   double sum; 
                   4371:  
                   4372:   for (i=1;i<=n;i++) { 
                   4373:     ip=indx[i]; 
                   4374:     sum=b[ip]; 
                   4375:     b[ip]=b[i]; 
                   4376:     if (ii) 
                   4377:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4378:     else if (sum) ii=i; 
                   4379:     b[i]=sum; 
                   4380:   } 
                   4381:   for (i=n;i>=1;i--) { 
                   4382:     sum=b[i]; 
                   4383:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4384:     b[i]=sum/a[i][i]; 
                   4385:   } 
                   4386: } 
                   4387: 
                   4388: void pstamp(FILE *fichier)
                   4389: {
1.196     brouard  4390:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4391: }
                   4392: 
1.253     brouard  4393: 
                   4394: 
1.126     brouard  4395: /************ Frequencies ********************/
1.251     brouard  4396: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4397:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4398:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4399: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4400:   
1.265     brouard  4401:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4402:   int iind=0, iage=0;
                   4403:   int mi; /* Effective wave */
                   4404:   int first;
                   4405:   double ***freq; /* Frequencies */
1.268     brouard  4406:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4407:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4408:   double *meanq, *stdq, *idq;
1.226     brouard  4409:   double **meanqt;
                   4410:   double *pp, **prop, *posprop, *pospropt;
                   4411:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4412:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4413:   double agebegin, ageend;
                   4414:     
                   4415:   pp=vector(1,nlstate);
1.251     brouard  4416:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4417:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4418:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4419:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4420:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4421:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4422:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4423:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4424:   strcpy(fileresp,"P_");
                   4425:   strcat(fileresp,fileresu);
                   4426:   /*strcat(fileresphtm,fileresu);*/
                   4427:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4428:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4429:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4430:     exit(0);
                   4431:   }
1.240     brouard  4432:   
1.226     brouard  4433:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4434:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4435:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4436:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4437:     fflush(ficlog);
                   4438:     exit(70); 
                   4439:   }
                   4440:   else{
                   4441:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4442: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4443: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4444:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4445:   }
1.237     brouard  4446:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4447:   
1.226     brouard  4448:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4449:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4450:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4451:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4452:     fflush(ficlog);
                   4453:     exit(70); 
1.240     brouard  4454:   } else{
1.226     brouard  4455:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4456: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4457: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4458:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4459:   }
1.240     brouard  4460:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4461:   
1.253     brouard  4462:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4463:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4464:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4465:   j1=0;
1.126     brouard  4466:   
1.227     brouard  4467:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4468:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4469:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4470:   
                   4471:   
1.226     brouard  4472:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4473:      reference=low_education V1=0,V2=0
                   4474:      med_educ                V1=1 V2=0, 
                   4475:      high_educ               V1=0 V2=1
                   4476:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4477:   */
1.249     brouard  4478:   dateintsum=0;
                   4479:   k2cpt=0;
                   4480: 
1.253     brouard  4481:   if(cptcoveff == 0 )
1.265     brouard  4482:     nl=1;  /* Constant and age model only */
1.253     brouard  4483:   else
                   4484:     nl=2;
1.265     brouard  4485: 
                   4486:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4487:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4488:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4489:    *     freq[s1][s2][iage] =0.
                   4490:    *     Loop on iind
                   4491:    *       ++freq[s1][s2][iage] weighted
                   4492:    *     end iind
                   4493:    *     if covariate and j!0
                   4494:    *       headers Variable on one line
                   4495:    *     endif cov j!=0
                   4496:    *     header of frequency table by age
                   4497:    *     Loop on age
                   4498:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4499:    *       pos+=freq[s1][s2][iage] weighted
                   4500:    *       Loop on s1 initial state
                   4501:    *         fprintf(ficresp
                   4502:    *       end s1
                   4503:    *     end age
                   4504:    *     if j!=0 computes starting values
                   4505:    *     end compute starting values
                   4506:    *   end j1
                   4507:    * end nl 
                   4508:    */
1.253     brouard  4509:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4510:     if(nj==1)
                   4511:       j=0;  /* First pass for the constant */
1.265     brouard  4512:     else{
1.253     brouard  4513:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4514:     }
1.251     brouard  4515:     first=1;
1.265     brouard  4516:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4517:       posproptt=0.;
                   4518:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4519:        scanf("%d", i);*/
                   4520:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4521:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4522:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4523:            freq[i][s2][m]=0;
1.251     brouard  4524:       
                   4525:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4526:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4527:          prop[i][m]=0;
                   4528:        posprop[i]=0;
                   4529:        pospropt[i]=0;
                   4530:       }
1.283     brouard  4531:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4532:         idq[z1]=0.;
                   4533:         meanq[z1]=0.;
                   4534:         stdq[z1]=0.;
1.283     brouard  4535:       }
                   4536:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4537:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4538:       /*         meanqt[m][z1]=0.; */
                   4539:       /*       } */
                   4540:       /* }       */
1.251     brouard  4541:       /* dateintsum=0; */
                   4542:       /* k2cpt=0; */
                   4543:       
1.265     brouard  4544:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4545:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4546:        bool=1;
                   4547:        if(j !=0){
                   4548:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4549:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4550:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4551:                /* if(Tvaraff[z1] ==-20){ */
                   4552:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4553:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4554:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4555:                /* }else  */
                   4556:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4557:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4558:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4559:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4560:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4561:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4562:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4563:                } /* Onlyf fixed */
                   4564:              } /* end z1 */
                   4565:            } /* cptcovn > 0 */
                   4566:          } /* end any */
                   4567:        }/* end j==0 */
1.265     brouard  4568:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4569:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4570:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4571:            m=mw[mi][iind];
                   4572:            if(j!=0){
                   4573:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4574:                for (z1=1; z1<=cptcoveff; z1++) {
                   4575:                  if( Fixed[Tmodelind[z1]]==1){
                   4576:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4577:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4578:                                                                                      value is -1, we don't select. It differs from the 
                   4579:                                                                                      constant and age model which counts them. */
                   4580:                      bool=0; /* not selected */
                   4581:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4582:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4583:                      bool=0;
                   4584:                    }
                   4585:                  }
                   4586:                }
                   4587:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4588:            } /* end j==0 */
                   4589:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4590:            if(bool==1){ /*Selected */
1.251     brouard  4591:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4592:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4593:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4594:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4595:              if(m >=firstpass && m <=lastpass){
                   4596:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4597:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4598:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4599:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4600:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4601:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4602:                if (m<lastpass) {
                   4603:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4604:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4605:                  if(s[m][iind]==-1)
                   4606:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4607:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.284     brouard  4608:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean */
                   4609:                    idq[z1]=idq[z1]+weight[iind];
                   4610:                    meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4611:                    stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4612:                  }
1.251     brouard  4613:                  /* if((int)agev[m][iind] == 55) */
                   4614:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4615:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4616:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4617:                }
1.251     brouard  4618:              } /* end if between passes */  
                   4619:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4620:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4621:                k2cpt++;
                   4622:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4623:              }
1.251     brouard  4624:            }else{
                   4625:              bool=1;
                   4626:            }/* end bool 2 */
                   4627:          } /* end m */
1.284     brouard  4628:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4629:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4630:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4631:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4632:          /* } */
1.251     brouard  4633:        } /* end bool */
                   4634:       } /* end iind = 1 to imx */
                   4635:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4636:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4637:       
                   4638:       
                   4639:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4640:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4641:         pstamp(ficresp);
1.251     brouard  4642:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4643:         pstamp(ficresp);
1.251     brouard  4644:        printf( "\n#********** Variable "); 
                   4645:        fprintf(ficresp, "\n#********** Variable "); 
                   4646:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4647:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4648:        fprintf(ficlog, "\n#********** Variable "); 
                   4649:        for (z1=1; z1<=cptcoveff; z1++){
                   4650:          if(!FixedV[Tvaraff[z1]]){
                   4651:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4652:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4653:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4654:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4655:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4656:          }else{
1.251     brouard  4657:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4658:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4659:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4660:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4661:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4662:          }
                   4663:        }
                   4664:        printf( "**********\n#");
                   4665:        fprintf(ficresp, "**********\n#");
                   4666:        fprintf(ficresphtm, "**********</h3>\n");
                   4667:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4668:        fprintf(ficlog, "**********\n");
                   4669:       }
1.284     brouard  4670:       /*
                   4671:        Printing means of quantitative variables if any
                   4672:       */
                   4673:       for (z1=1; z1<= nqfveff; z1++) {
1.285     brouard  4674:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.0f individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.284     brouard  4675:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
                   4676:        if(weightopt==1){
                   4677:          printf(" Weighted mean and standard deviation of");
                   4678:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4679:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4680:        }
1.285     brouard  4681:        printf(" fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4682:        fprintf(ficlog," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4683:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
1.284     brouard  4684:       }
                   4685:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4686:       /*       for(m=1;m<=lastpass;m++){ */
                   4687:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4688:       /*   } */
                   4689:       /* } */
1.283     brouard  4690: 
1.251     brouard  4691:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4692:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4693:         fprintf(ficresp, " Age");
                   4694:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4695:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4696:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4697:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4698:       }
1.265     brouard  4699:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4700:       fprintf(ficresphtm, "\n");
                   4701:       
                   4702:       /* Header of frequency table by age */
                   4703:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4704:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4705:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4706:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4707:          if(s2!=0 && m!=0)
                   4708:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4709:        }
1.226     brouard  4710:       }
1.251     brouard  4711:       fprintf(ficresphtmfr, "\n");
                   4712:     
                   4713:       /* For each age */
                   4714:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4715:        fprintf(ficresphtm,"<tr>");
                   4716:        if(iage==iagemax+1){
                   4717:          fprintf(ficlog,"1");
                   4718:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4719:        }else if(iage==iagemax+2){
                   4720:          fprintf(ficlog,"0");
                   4721:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4722:        }else if(iage==iagemax+3){
                   4723:          fprintf(ficlog,"Total");
                   4724:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4725:        }else{
1.240     brouard  4726:          if(first==1){
1.251     brouard  4727:            first=0;
                   4728:            printf("See log file for details...\n");
                   4729:          }
                   4730:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4731:          fprintf(ficlog,"Age %d", iage);
                   4732:        }
1.265     brouard  4733:        for(s1=1; s1 <=nlstate ; s1++){
                   4734:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4735:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4736:        }
1.265     brouard  4737:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4738:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4739:            pos += freq[s1][m][iage];
                   4740:          if(pp[s1]>=1.e-10){
1.251     brouard  4741:            if(first==1){
1.265     brouard  4742:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4743:            }
1.265     brouard  4744:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4745:          }else{
                   4746:            if(first==1)
1.265     brouard  4747:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4748:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4749:          }
                   4750:        }
                   4751:       
1.265     brouard  4752:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4753:          /* posprop[s1]=0; */
                   4754:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4755:            pp[s1] += freq[s1][m][iage];
                   4756:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4757:       
                   4758:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4759:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4760:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4761:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4762:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4763:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4764:        }
                   4765:        
                   4766:        /* Writing ficresp */
                   4767:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4768:           if( iage <= iagemax){
                   4769:            fprintf(ficresp," %d",iage);
                   4770:           }
                   4771:         }else if( nj==2){
                   4772:           if( iage <= iagemax){
                   4773:            fprintf(ficresp," %d",iage);
                   4774:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4775:           }
1.240     brouard  4776:        }
1.265     brouard  4777:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4778:          if(pos>=1.e-5){
1.251     brouard  4779:            if(first==1)
1.265     brouard  4780:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4781:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4782:          }else{
                   4783:            if(first==1)
1.265     brouard  4784:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4785:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4786:          }
                   4787:          if( iage <= iagemax){
                   4788:            if(pos>=1.e-5){
1.265     brouard  4789:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4790:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4791:               }else if( nj==2){
                   4792:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4793:               }
                   4794:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4795:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4796:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4797:            } else{
                   4798:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4799:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4800:            }
1.240     brouard  4801:          }
1.265     brouard  4802:          pospropt[s1] +=posprop[s1];
                   4803:        } /* end loop s1 */
1.251     brouard  4804:        /* pospropt=0.; */
1.265     brouard  4805:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4806:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4807:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4808:              if(first==1){
1.265     brouard  4809:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4810:              }
1.265     brouard  4811:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4812:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4813:            }
1.265     brouard  4814:            if(s1!=0 && m!=0)
                   4815:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4816:          }
1.265     brouard  4817:        } /* end loop s1 */
1.251     brouard  4818:        posproptt=0.; 
1.265     brouard  4819:        for(s1=1; s1 <=nlstate; s1++){
                   4820:          posproptt += pospropt[s1];
1.251     brouard  4821:        }
                   4822:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4823:        fprintf(ficresphtm,"</tr>\n");
                   4824:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4825:          if(iage <= iagemax)
                   4826:            fprintf(ficresp,"\n");
1.240     brouard  4827:        }
1.251     brouard  4828:        if(first==1)
                   4829:          printf("Others in log...\n");
                   4830:        fprintf(ficlog,"\n");
                   4831:       } /* end loop age iage */
1.265     brouard  4832:       
1.251     brouard  4833:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4834:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4835:        if(posproptt < 1.e-5){
1.265     brouard  4836:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4837:        }else{
1.265     brouard  4838:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4839:        }
1.226     brouard  4840:       }
1.251     brouard  4841:       fprintf(ficresphtm,"</tr>\n");
                   4842:       fprintf(ficresphtm,"</table>\n");
                   4843:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4844:       if(posproptt < 1.e-5){
1.251     brouard  4845:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4846:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4847:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4848:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4849:        invalidvarcomb[j1]=1;
1.226     brouard  4850:       }else{
1.251     brouard  4851:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4852:        invalidvarcomb[j1]=0;
1.226     brouard  4853:       }
1.251     brouard  4854:       fprintf(ficresphtmfr,"</table>\n");
                   4855:       fprintf(ficlog,"\n");
                   4856:       if(j!=0){
                   4857:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4858:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4859:          for(k=1; k <=(nlstate+ndeath); k++){
                   4860:            if (k != i) {
1.265     brouard  4861:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4862:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4863:                  if(j1==1){ /* All dummy covariates to zero */
                   4864:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4865:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4866:                    printf("%d%d ",i,k);
                   4867:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4868:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4869:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4870:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4871:                  }
1.253     brouard  4872:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4873:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4874:                    x[iage]= (double)iage;
                   4875:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4876:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4877:                  }
1.268     brouard  4878:                  /* Some are not finite, but linreg will ignore these ages */
                   4879:                  no=0;
1.253     brouard  4880:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4881:                  pstart[s1]=b;
                   4882:                  pstart[s1-1]=a;
1.252     brouard  4883:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4884:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4885:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4886:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4887:                  printf("%d%d ",i,k);
                   4888:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4889:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4890:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4891:                  ;
                   4892:                }
                   4893:                /* printf("%12.7f )", param[i][jj][k]); */
                   4894:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4895:                s1++; 
1.251     brouard  4896:              } /* end jj */
                   4897:            } /* end k!= i */
                   4898:          } /* end k */
1.265     brouard  4899:        } /* end i, s1 */
1.251     brouard  4900:       } /* end j !=0 */
                   4901:     } /* end selected combination of covariate j1 */
                   4902:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4903:       printf("#Freqsummary: Starting values for the constants:\n");
                   4904:       fprintf(ficlog,"\n");
1.265     brouard  4905:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4906:        for(k=1; k <=(nlstate+ndeath); k++){
                   4907:          if (k != i) {
                   4908:            printf("%d%d ",i,k);
                   4909:            fprintf(ficlog,"%d%d ",i,k);
                   4910:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4911:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4912:              if(jj==1){ /* Age has to be done */
1.265     brouard  4913:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4914:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4915:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4916:              }
                   4917:              /* printf("%12.7f )", param[i][jj][k]); */
                   4918:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4919:              s1++; 
1.250     brouard  4920:            }
1.251     brouard  4921:            printf("\n");
                   4922:            fprintf(ficlog,"\n");
1.250     brouard  4923:          }
                   4924:        }
1.284     brouard  4925:       } /* end of state i */
1.251     brouard  4926:       printf("#Freqsummary\n");
                   4927:       fprintf(ficlog,"\n");
1.265     brouard  4928:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4929:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4930:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4931:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4932:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4933:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4934:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4935:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4936:          /* } */
                   4937:        }
1.265     brouard  4938:       } /* end loop s1 */
1.251     brouard  4939:       
                   4940:       printf("\n");
                   4941:       fprintf(ficlog,"\n");
                   4942:     } /* end j=0 */
1.249     brouard  4943:   } /* end j */
1.252     brouard  4944: 
1.253     brouard  4945:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4946:     for(i=1, jk=1; i <=nlstate; i++){
                   4947:       for(j=1; j <=nlstate+ndeath; j++){
                   4948:        if(j!=i){
                   4949:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4950:          printf("%1d%1d",i,j);
                   4951:          fprintf(ficparo,"%1d%1d",i,j);
                   4952:          for(k=1; k<=ncovmodel;k++){
                   4953:            /*    printf(" %lf",param[i][j][k]); */
                   4954:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4955:            p[jk]=pstart[jk];
                   4956:            printf(" %f ",pstart[jk]);
                   4957:            fprintf(ficparo," %f ",pstart[jk]);
                   4958:            jk++;
                   4959:          }
                   4960:          printf("\n");
                   4961:          fprintf(ficparo,"\n");
                   4962:        }
                   4963:       }
                   4964:     }
                   4965:   } /* end mle=-2 */
1.226     brouard  4966:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4967:   
1.226     brouard  4968:   fclose(ficresp);
                   4969:   fclose(ficresphtm);
                   4970:   fclose(ficresphtmfr);
1.283     brouard  4971:   free_vector(idq,1,nqfveff);
1.226     brouard  4972:   free_vector(meanq,1,nqfveff);
1.284     brouard  4973:   free_vector(stdq,1,nqfveff);
1.226     brouard  4974:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4975:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4976:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4977:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4978:   free_vector(pospropt,1,nlstate);
                   4979:   free_vector(posprop,1,nlstate);
1.251     brouard  4980:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4981:   free_vector(pp,1,nlstate);
                   4982:   /* End of freqsummary */
                   4983: }
1.126     brouard  4984: 
1.268     brouard  4985: /* Simple linear regression */
                   4986: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4987: 
                   4988:   /* y=a+bx regression */
                   4989:   double   sumx = 0.0;                        /* sum of x                      */
                   4990:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   4991:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   4992:   double   sumy = 0.0;                        /* sum of y                      */
                   4993:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   4994:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   4995:   double yhat;
                   4996:   
                   4997:   double denom=0;
                   4998:   int i;
                   4999:   int ne=*no;
                   5000:   
                   5001:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5002:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5003:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5004:       continue;
                   5005:     }
                   5006:     ne=ne+1;
                   5007:     sumx  += x[i];       
                   5008:     sumx2 += x[i]*x[i];  
                   5009:     sumxy += x[i] * y[i];
                   5010:     sumy  += y[i];      
                   5011:     sumy2 += y[i]*y[i]; 
                   5012:     denom = (ne * sumx2 - sumx*sumx);
                   5013:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5014:   } 
                   5015:   
                   5016:   denom = (ne * sumx2 - sumx*sumx);
                   5017:   if (denom == 0) {
                   5018:     // vertical, slope m is infinity
                   5019:     *b = INFINITY;
                   5020:     *a = 0;
                   5021:     if (r) *r = 0;
                   5022:     return 1;
                   5023:   }
                   5024:   
                   5025:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5026:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5027:   if (r!=NULL) {
                   5028:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5029:       sqrt((sumx2 - sumx*sumx/ne) *
                   5030:           (sumy2 - sumy*sumy/ne));
                   5031:   }
                   5032:   *no=ne;
                   5033:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5034:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5035:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5036:       continue;
                   5037:     }
                   5038:     ne=ne+1;
                   5039:     yhat = y[i] - *a -*b* x[i];
                   5040:     sume2  += yhat * yhat ;       
                   5041:     
                   5042:     denom = (ne * sumx2 - sumx*sumx);
                   5043:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5044:   } 
                   5045:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5046:   *sa= *sb * sqrt(sumx2/ne);
                   5047:   
                   5048:   return 0; 
                   5049: }
                   5050: 
1.126     brouard  5051: /************ Prevalence ********************/
1.227     brouard  5052: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5053: {  
                   5054:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5055:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5056:      We still use firstpass and lastpass as another selection.
                   5057:   */
1.126     brouard  5058:  
1.227     brouard  5059:   int i, m, jk, j1, bool, z1,j, iv;
                   5060:   int mi; /* Effective wave */
                   5061:   int iage;
                   5062:   double agebegin, ageend;
                   5063: 
                   5064:   double **prop;
                   5065:   double posprop; 
                   5066:   double  y2; /* in fractional years */
                   5067:   int iagemin, iagemax;
                   5068:   int first; /** to stop verbosity which is redirected to log file */
                   5069: 
                   5070:   iagemin= (int) agemin;
                   5071:   iagemax= (int) agemax;
                   5072:   /*pp=vector(1,nlstate);*/
1.251     brouard  5073:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5074:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5075:   j1=0;
1.222     brouard  5076:   
1.227     brouard  5077:   /*j=cptcoveff;*/
                   5078:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5079:   
1.288     brouard  5080:   first=0;
1.227     brouard  5081:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5082:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5083:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5084:        prop[i][iage]=0.0;
                   5085:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5086:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5087:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5088:     
                   5089:     for (i=1; i<=imx; i++) { /* Each individual */
                   5090:       bool=1;
                   5091:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5092:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5093:        m=mw[mi][i];
                   5094:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5095:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5096:        for (z1=1; z1<=cptcoveff; z1++){
                   5097:          if( Fixed[Tmodelind[z1]]==1){
                   5098:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5099:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5100:              bool=0;
                   5101:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5102:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5103:              bool=0;
                   5104:            }
                   5105:        }
                   5106:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5107:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5108:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5109:          if(m >=firstpass && m <=lastpass){
                   5110:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5111:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5112:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5113:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5114:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5115:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5116:                exit(1);
                   5117:              }
                   5118:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5119:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5120:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5121:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5122:              } /* end valid statuses */ 
                   5123:            } /* end selection of dates */
                   5124:          } /* end selection of waves */
                   5125:        } /* end bool */
                   5126:       } /* end wave */
                   5127:     } /* end individual */
                   5128:     for(i=iagemin; i <= iagemax+3; i++){  
                   5129:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5130:        posprop += prop[jk][i]; 
                   5131:       } 
                   5132:       
                   5133:       for(jk=1; jk <=nlstate ; jk++){      
                   5134:        if( i <=  iagemax){ 
                   5135:          if(posprop>=1.e-5){ 
                   5136:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5137:          } else{
1.288     brouard  5138:            if(!first){
                   5139:              first=1;
1.266     brouard  5140:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5141:            }else{
1.288     brouard  5142:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5143:            }
                   5144:          }
                   5145:        } 
                   5146:       }/* end jk */ 
                   5147:     }/* end i */ 
1.222     brouard  5148:      /*} *//* end i1 */
1.227     brouard  5149:   } /* end j1 */
1.222     brouard  5150:   
1.227     brouard  5151:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5152:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5153:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5154: }  /* End of prevalence */
1.126     brouard  5155: 
                   5156: /************* Waves Concatenation ***************/
                   5157: 
                   5158: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5159: {
                   5160:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5161:      Death is a valid wave (if date is known).
                   5162:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5163:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5164:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5165:   */
1.126     brouard  5166: 
1.224     brouard  5167:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5168:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5169:      double sum=0., jmean=0.;*/
1.224     brouard  5170:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5171:   int j, k=0,jk, ju, jl;
                   5172:   double sum=0.;
                   5173:   first=0;
1.214     brouard  5174:   firstwo=0;
1.217     brouard  5175:   firsthree=0;
1.218     brouard  5176:   firstfour=0;
1.164     brouard  5177:   jmin=100000;
1.126     brouard  5178:   jmax=-1;
                   5179:   jmean=0.;
1.224     brouard  5180: 
                   5181: /* Treating live states */
1.214     brouard  5182:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5183:     mi=0;  /* First valid wave */
1.227     brouard  5184:     mli=0; /* Last valid wave */
1.126     brouard  5185:     m=firstpass;
1.214     brouard  5186:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5187:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5188:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5189:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5190:        mw[++mi][i]=m;
                   5191:        mli=m;
1.224     brouard  5192:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5193:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5194:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5195:       }
1.227     brouard  5196:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5197: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5198:        break;
1.224     brouard  5199: #else
1.227     brouard  5200:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5201:          if(firsthree == 0){
1.262     brouard  5202:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5203:            firsthree=1;
                   5204:          }
1.262     brouard  5205:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5206:          mw[++mi][i]=m;
                   5207:          mli=m;
                   5208:        }
                   5209:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5210:          nbwarn++;
                   5211:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5212:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5213:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5214:          }
                   5215:          break;
                   5216:        }
                   5217:        break;
1.224     brouard  5218: #endif
1.227     brouard  5219:       }/* End m >= lastpass */
1.126     brouard  5220:     }/* end while */
1.224     brouard  5221: 
1.227     brouard  5222:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5223:     /* After last pass */
1.224     brouard  5224: /* Treating death states */
1.214     brouard  5225:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5226:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5227:       /* } */
1.126     brouard  5228:       mi++;    /* Death is another wave */
                   5229:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5230:       /* Only death is a correct wave */
1.126     brouard  5231:       mw[mi][i]=m;
1.257     brouard  5232:     } /* else not in a death state */
1.224     brouard  5233: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5234:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5235:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5236:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5237:          nbwarn++;
                   5238:          if(firstfiv==0){
                   5239:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5240:            firstfiv=1;
                   5241:          }else{
                   5242:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5243:          }
                   5244:        }else{ /* Death occured afer last wave potential bias */
                   5245:          nberr++;
                   5246:          if(firstwo==0){
1.257     brouard  5247:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5248:            firstwo=1;
                   5249:          }
1.257     brouard  5250:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5251:        }
1.257     brouard  5252:       }else{ /* if date of interview is unknown */
1.227     brouard  5253:        /* death is known but not confirmed by death status at any wave */
                   5254:        if(firstfour==0){
                   5255:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5256:          firstfour=1;
                   5257:        }
                   5258:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5259:       }
1.224     brouard  5260:     } /* end if date of death is known */
                   5261: #endif
                   5262:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5263:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5264:     if(mi==0){
                   5265:       nbwarn++;
                   5266:       if(first==0){
1.227     brouard  5267:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5268:        first=1;
1.126     brouard  5269:       }
                   5270:       if(first==1){
1.227     brouard  5271:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5272:       }
                   5273:     } /* end mi==0 */
                   5274:   } /* End individuals */
1.214     brouard  5275:   /* wav and mw are no more changed */
1.223     brouard  5276:        
1.214     brouard  5277:   
1.126     brouard  5278:   for(i=1; i<=imx; i++){
                   5279:     for(mi=1; mi<wav[i];mi++){
                   5280:       if (stepm <=0)
1.227     brouard  5281:        dh[mi][i]=1;
1.126     brouard  5282:       else{
1.260     brouard  5283:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5284:          if (agedc[i] < 2*AGESUP) {
                   5285:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5286:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5287:            else if(j<0){
                   5288:              nberr++;
                   5289:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5290:              j=1; /* Temporary Dangerous patch */
                   5291:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5292:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5293:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5294:            }
                   5295:            k=k+1;
                   5296:            if (j >= jmax){
                   5297:              jmax=j;
                   5298:              ijmax=i;
                   5299:            }
                   5300:            if (j <= jmin){
                   5301:              jmin=j;
                   5302:              ijmin=i;
                   5303:            }
                   5304:            sum=sum+j;
                   5305:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5306:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5307:          }
                   5308:        }
                   5309:        else{
                   5310:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5311: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5312:                                        
1.227     brouard  5313:          k=k+1;
                   5314:          if (j >= jmax) {
                   5315:            jmax=j;
                   5316:            ijmax=i;
                   5317:          }
                   5318:          else if (j <= jmin){
                   5319:            jmin=j;
                   5320:            ijmin=i;
                   5321:          }
                   5322:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5323:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5324:          if(j<0){
                   5325:            nberr++;
                   5326:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5327:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5328:          }
                   5329:          sum=sum+j;
                   5330:        }
                   5331:        jk= j/stepm;
                   5332:        jl= j -jk*stepm;
                   5333:        ju= j -(jk+1)*stepm;
                   5334:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5335:          if(jl==0){
                   5336:            dh[mi][i]=jk;
                   5337:            bh[mi][i]=0;
                   5338:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5339:                  * to avoid the price of an extra matrix product in likelihood */
                   5340:            dh[mi][i]=jk+1;
                   5341:            bh[mi][i]=ju;
                   5342:          }
                   5343:        }else{
                   5344:          if(jl <= -ju){
                   5345:            dh[mi][i]=jk;
                   5346:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5347:                                 * is higher than the multiple of stepm and negative otherwise.
                   5348:                                 */
                   5349:          }
                   5350:          else{
                   5351:            dh[mi][i]=jk+1;
                   5352:            bh[mi][i]=ju;
                   5353:          }
                   5354:          if(dh[mi][i]==0){
                   5355:            dh[mi][i]=1; /* At least one step */
                   5356:            bh[mi][i]=ju; /* At least one step */
                   5357:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5358:          }
                   5359:        } /* end if mle */
1.126     brouard  5360:       }
                   5361:     } /* end wave */
                   5362:   }
                   5363:   jmean=sum/k;
                   5364:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5365:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5366: }
1.126     brouard  5367: 
                   5368: /*********** Tricode ****************************/
1.220     brouard  5369:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5370:  {
                   5371:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5372:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5373:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5374:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5375:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5376:     */
1.130     brouard  5377: 
1.242     brouard  5378:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5379:    int modmaxcovj=0; /* Modality max of covariates j */
                   5380:    int cptcode=0; /* Modality max of covariates j */
                   5381:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5382: 
                   5383: 
1.242     brouard  5384:    /* cptcoveff=0;  */
                   5385:    /* *cptcov=0; */
1.126     brouard  5386:  
1.242     brouard  5387:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5388:    for (k=1; k <= maxncov; k++)
                   5389:      for(j=1; j<=2; j++)
                   5390:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5391: 
1.242     brouard  5392:    /* Loop on covariates without age and products and no quantitative variable */
                   5393:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5394:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5395:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5396:        switch(Fixed[k]) {
                   5397:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5398:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5399:           ij=(int)(covar[Tvar[k]][i]);
                   5400:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5401:            * If product of Vn*Vm, still boolean *:
                   5402:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5403:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5404:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5405:              modality of the nth covariate of individual i. */
                   5406:           if (ij > modmaxcovj)
                   5407:             modmaxcovj=ij; 
                   5408:           else if (ij < modmincovj) 
                   5409:             modmincovj=ij; 
1.287     brouard  5410:           if (ij <0 || ij >1 ){
                   5411:             printf("Information, IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5412:             fprintf(ficlog,"Information, currently IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5413:           }
                   5414:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5415:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5416:             exit(1);
                   5417:           }else
                   5418:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5419:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5420:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5421:           /* getting the maximum value of the modality of the covariate
                   5422:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5423:              female ies 1, then modmaxcovj=1.
                   5424:           */
                   5425:         } /* end for loop on individuals i */
                   5426:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5427:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5428:         cptcode=modmaxcovj;
                   5429:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5430:         /*for (i=0; i<=cptcode; i++) {*/
                   5431:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5432:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5433:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5434:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5435:             if( j != -1){
                   5436:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5437:                                  covariate for which somebody answered excluding 
                   5438:                                  undefined. Usually 2: 0 and 1. */
                   5439:             }
                   5440:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5441:                                     covariate for which somebody answered including 
                   5442:                                     undefined. Usually 3: -1, 0 and 1. */
                   5443:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5444:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5445:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5446:                        
1.242     brouard  5447:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5448:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5449:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5450:         /* modmincovj=3; modmaxcovj = 7; */
                   5451:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5452:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5453:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5454:         /* nbcode[Tvar[j]][ij]=k; */
                   5455:         /* nbcode[Tvar[j]][1]=0; */
                   5456:         /* nbcode[Tvar[j]][2]=1; */
                   5457:         /* nbcode[Tvar[j]][3]=2; */
                   5458:         /* To be continued (not working yet). */
                   5459:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5460: 
                   5461:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5462:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5463:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5464:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5465:         /*, could be restored in the future */
                   5466:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5467:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5468:             break;
                   5469:           }
                   5470:           ij++;
1.287     brouard  5471:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5472:           cptcode = ij; /* New max modality for covar j */
                   5473:         } /* end of loop on modality i=-1 to 1 or more */
                   5474:         break;
                   5475:        case 1: /* Testing on varying covariate, could be simple and
                   5476:                * should look at waves or product of fixed *
                   5477:                * varying. No time to test -1, assuming 0 and 1 only */
                   5478:         ij=0;
                   5479:         for(i=0; i<=1;i++){
                   5480:           nbcode[Tvar[k]][++ij]=i;
                   5481:         }
                   5482:         break;
                   5483:        default:
                   5484:         break;
                   5485:        } /* end switch */
                   5486:      } /* end dummy test */
1.287     brouard  5487:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5488:   
                   5489:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5490:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5491:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5492:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5493:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5494:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5495:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5496:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5497:   
                   5498:    ij=0;
                   5499:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5500:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5501:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5502:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5503:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5504:        /* If product not in single variable we don't print results */
                   5505:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5506:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5507:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5508:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5509:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5510:        if(Fixed[k]!=0)
                   5511:         anyvaryingduminmodel=1;
                   5512:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5513:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5514:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5515:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5516:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5517:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5518:      } 
                   5519:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5520:    /* ij--; */
                   5521:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5522:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5523:                * because they can be excluded from the model and real
                   5524:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5525:    for(j=ij+1; j<= cptcovt; j++){
                   5526:      Tvaraff[j]=0;
                   5527:      Tmodelind[j]=0;
                   5528:    }
                   5529:    for(j=ntveff+1; j<= cptcovt; j++){
                   5530:      TmodelInvind[j]=0;
                   5531:    }
                   5532:    /* To be sorted */
                   5533:    ;
                   5534:  }
1.126     brouard  5535: 
1.145     brouard  5536: 
1.126     brouard  5537: /*********** Health Expectancies ****************/
                   5538: 
1.235     brouard  5539:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5540: 
                   5541: {
                   5542:   /* Health expectancies, no variances */
1.164     brouard  5543:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5544:   int nhstepma, nstepma; /* Decreasing with age */
                   5545:   double age, agelim, hf;
                   5546:   double ***p3mat;
                   5547:   double eip;
                   5548: 
1.238     brouard  5549:   /* pstamp(ficreseij); */
1.126     brouard  5550:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5551:   fprintf(ficreseij,"# Age");
                   5552:   for(i=1; i<=nlstate;i++){
                   5553:     for(j=1; j<=nlstate;j++){
                   5554:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5555:     }
                   5556:     fprintf(ficreseij," e%1d. ",i);
                   5557:   }
                   5558:   fprintf(ficreseij,"\n");
                   5559: 
                   5560:   
                   5561:   if(estepm < stepm){
                   5562:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5563:   }
                   5564:   else  hstepm=estepm;   
                   5565:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5566:    * This is mainly to measure the difference between two models: for example
                   5567:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5568:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5569:    * progression in between and thus overestimating or underestimating according
                   5570:    * to the curvature of the survival function. If, for the same date, we 
                   5571:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5572:    * to compare the new estimate of Life expectancy with the same linear 
                   5573:    * hypothesis. A more precise result, taking into account a more precise
                   5574:    * curvature will be obtained if estepm is as small as stepm. */
                   5575: 
                   5576:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5577:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5578:      nhstepm is the number of hstepm from age to agelim 
                   5579:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5580:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5581:      and note for a fixed period like estepm months */
                   5582:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5583:      survival function given by stepm (the optimization length). Unfortunately it
                   5584:      means that if the survival funtion is printed only each two years of age and if
                   5585:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5586:      results. So we changed our mind and took the option of the best precision.
                   5587:   */
                   5588:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5589: 
                   5590:   agelim=AGESUP;
                   5591:   /* If stepm=6 months */
                   5592:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5593:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5594:     
                   5595: /* nhstepm age range expressed in number of stepm */
                   5596:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5597:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5598:   /* if (stepm >= YEARM) hstepm=1;*/
                   5599:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5600:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5601: 
                   5602:   for (age=bage; age<=fage; age ++){ 
                   5603:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5604:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5605:     /* if (stepm >= YEARM) hstepm=1;*/
                   5606:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5607: 
                   5608:     /* If stepm=6 months */
                   5609:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5610:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5611:     
1.235     brouard  5612:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5613:     
                   5614:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5615:     
                   5616:     printf("%d|",(int)age);fflush(stdout);
                   5617:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5618:     
                   5619:     /* Computing expectancies */
                   5620:     for(i=1; i<=nlstate;i++)
                   5621:       for(j=1; j<=nlstate;j++)
                   5622:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5623:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5624:          
                   5625:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5626: 
                   5627:        }
                   5628: 
                   5629:     fprintf(ficreseij,"%3.0f",age );
                   5630:     for(i=1; i<=nlstate;i++){
                   5631:       eip=0;
                   5632:       for(j=1; j<=nlstate;j++){
                   5633:        eip +=eij[i][j][(int)age];
                   5634:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5635:       }
                   5636:       fprintf(ficreseij,"%9.4f", eip );
                   5637:     }
                   5638:     fprintf(ficreseij,"\n");
                   5639:     
                   5640:   }
                   5641:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5642:   printf("\n");
                   5643:   fprintf(ficlog,"\n");
                   5644:   
                   5645: }
                   5646: 
1.235     brouard  5647:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5648: 
                   5649: {
                   5650:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5651:      to initial status i, ei. .
1.126     brouard  5652:   */
                   5653:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5654:   int nhstepma, nstepma; /* Decreasing with age */
                   5655:   double age, agelim, hf;
                   5656:   double ***p3matp, ***p3matm, ***varhe;
                   5657:   double **dnewm,**doldm;
                   5658:   double *xp, *xm;
                   5659:   double **gp, **gm;
                   5660:   double ***gradg, ***trgradg;
                   5661:   int theta;
                   5662: 
                   5663:   double eip, vip;
                   5664: 
                   5665:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5666:   xp=vector(1,npar);
                   5667:   xm=vector(1,npar);
                   5668:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5669:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5670:   
                   5671:   pstamp(ficresstdeij);
                   5672:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5673:   fprintf(ficresstdeij,"# Age");
                   5674:   for(i=1; i<=nlstate;i++){
                   5675:     for(j=1; j<=nlstate;j++)
                   5676:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5677:     fprintf(ficresstdeij," e%1d. ",i);
                   5678:   }
                   5679:   fprintf(ficresstdeij,"\n");
                   5680: 
                   5681:   pstamp(ficrescveij);
                   5682:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5683:   fprintf(ficrescveij,"# Age");
                   5684:   for(i=1; i<=nlstate;i++)
                   5685:     for(j=1; j<=nlstate;j++){
                   5686:       cptj= (j-1)*nlstate+i;
                   5687:       for(i2=1; i2<=nlstate;i2++)
                   5688:        for(j2=1; j2<=nlstate;j2++){
                   5689:          cptj2= (j2-1)*nlstate+i2;
                   5690:          if(cptj2 <= cptj)
                   5691:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5692:        }
                   5693:     }
                   5694:   fprintf(ficrescveij,"\n");
                   5695:   
                   5696:   if(estepm < stepm){
                   5697:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5698:   }
                   5699:   else  hstepm=estepm;   
                   5700:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5701:    * This is mainly to measure the difference between two models: for example
                   5702:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5703:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5704:    * progression in between and thus overestimating or underestimating according
                   5705:    * to the curvature of the survival function. If, for the same date, we 
                   5706:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5707:    * to compare the new estimate of Life expectancy with the same linear 
                   5708:    * hypothesis. A more precise result, taking into account a more precise
                   5709:    * curvature will be obtained if estepm is as small as stepm. */
                   5710: 
                   5711:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5712:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5713:      nhstepm is the number of hstepm from age to agelim 
                   5714:      nstepm is the number of stepm from age to agelin. 
                   5715:      Look at hpijx to understand the reason of that which relies in memory size
                   5716:      and note for a fixed period like estepm months */
                   5717:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5718:      survival function given by stepm (the optimization length). Unfortunately it
                   5719:      means that if the survival funtion is printed only each two years of age and if
                   5720:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5721:      results. So we changed our mind and took the option of the best precision.
                   5722:   */
                   5723:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5724: 
                   5725:   /* If stepm=6 months */
                   5726:   /* nhstepm age range expressed in number of stepm */
                   5727:   agelim=AGESUP;
                   5728:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5729:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5730:   /* if (stepm >= YEARM) hstepm=1;*/
                   5731:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5732:   
                   5733:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5734:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5735:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5736:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5737:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5738:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5739: 
                   5740:   for (age=bage; age<=fage; age ++){ 
                   5741:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5742:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5743:     /* if (stepm >= YEARM) hstepm=1;*/
                   5744:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5745:                
1.126     brouard  5746:     /* If stepm=6 months */
                   5747:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5748:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5749:     
                   5750:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5751:                
1.126     brouard  5752:     /* Computing  Variances of health expectancies */
                   5753:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5754:        decrease memory allocation */
                   5755:     for(theta=1; theta <=npar; theta++){
                   5756:       for(i=1; i<=npar; i++){ 
1.222     brouard  5757:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5758:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5759:       }
1.235     brouard  5760:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5761:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5762:                        
1.126     brouard  5763:       for(j=1; j<= nlstate; j++){
1.222     brouard  5764:        for(i=1; i<=nlstate; i++){
                   5765:          for(h=0; h<=nhstepm-1; h++){
                   5766:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5767:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5768:          }
                   5769:        }
1.126     brouard  5770:       }
1.218     brouard  5771:                        
1.126     brouard  5772:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5773:        for(h=0; h<=nhstepm-1; h++){
                   5774:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5775:        }
1.126     brouard  5776:     }/* End theta */
                   5777:     
                   5778:     
                   5779:     for(h=0; h<=nhstepm-1; h++)
                   5780:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5781:        for(theta=1; theta <=npar; theta++)
                   5782:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5783:     
1.218     brouard  5784:                
1.222     brouard  5785:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5786:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5787:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5788:                
1.222     brouard  5789:     printf("%d|",(int)age);fflush(stdout);
                   5790:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5791:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5792:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5793:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5794:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5795:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5796:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5797:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5798:       }
                   5799:     }
1.218     brouard  5800:                
1.126     brouard  5801:     /* Computing expectancies */
1.235     brouard  5802:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5803:     for(i=1; i<=nlstate;i++)
                   5804:       for(j=1; j<=nlstate;j++)
1.222     brouard  5805:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5806:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5807:                                        
1.222     brouard  5808:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5809:                                        
1.222     brouard  5810:        }
1.269     brouard  5811: 
                   5812:     /* Standard deviation of expectancies ij */                
1.126     brouard  5813:     fprintf(ficresstdeij,"%3.0f",age );
                   5814:     for(i=1; i<=nlstate;i++){
                   5815:       eip=0.;
                   5816:       vip=0.;
                   5817:       for(j=1; j<=nlstate;j++){
1.222     brouard  5818:        eip += eij[i][j][(int)age];
                   5819:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5820:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5821:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5822:       }
                   5823:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5824:     }
                   5825:     fprintf(ficresstdeij,"\n");
1.218     brouard  5826:                
1.269     brouard  5827:     /* Variance of expectancies ij */          
1.126     brouard  5828:     fprintf(ficrescveij,"%3.0f",age );
                   5829:     for(i=1; i<=nlstate;i++)
                   5830:       for(j=1; j<=nlstate;j++){
1.222     brouard  5831:        cptj= (j-1)*nlstate+i;
                   5832:        for(i2=1; i2<=nlstate;i2++)
                   5833:          for(j2=1; j2<=nlstate;j2++){
                   5834:            cptj2= (j2-1)*nlstate+i2;
                   5835:            if(cptj2 <= cptj)
                   5836:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5837:          }
1.126     brouard  5838:       }
                   5839:     fprintf(ficrescveij,"\n");
1.218     brouard  5840:                
1.126     brouard  5841:   }
                   5842:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5843:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5844:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5845:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5846:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5847:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5848:   printf("\n");
                   5849:   fprintf(ficlog,"\n");
1.218     brouard  5850:        
1.126     brouard  5851:   free_vector(xm,1,npar);
                   5852:   free_vector(xp,1,npar);
                   5853:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5854:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5855:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5856: }
1.218     brouard  5857:  
1.126     brouard  5858: /************ Variance ******************/
1.235     brouard  5859:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5860:  {
1.279     brouard  5861:    /** Variance of health expectancies 
                   5862:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5863:     * double **newm;
                   5864:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5865:     */
1.218     brouard  5866:   
                   5867:    /* int movingaverage(); */
                   5868:    double **dnewm,**doldm;
                   5869:    double **dnewmp,**doldmp;
                   5870:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  5871:    int first=0;
1.218     brouard  5872:    int k;
                   5873:    double *xp;
1.279     brouard  5874:    double **gp, **gm;  /**< for var eij */
                   5875:    double ***gradg, ***trgradg; /**< for var eij */
                   5876:    double **gradgp, **trgradgp; /**< for var p point j */
                   5877:    double *gpp, *gmp; /**< for var p point j */
                   5878:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5879:    double ***p3mat;
                   5880:    double age,agelim, hf;
                   5881:    /* double ***mobaverage; */
                   5882:    int theta;
                   5883:    char digit[4];
                   5884:    char digitp[25];
                   5885: 
                   5886:    char fileresprobmorprev[FILENAMELENGTH];
                   5887: 
                   5888:    if(popbased==1){
                   5889:      if(mobilav!=0)
                   5890:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5891:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5892:    }
                   5893:    else 
                   5894:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5895: 
1.218     brouard  5896:    /* if (mobilav!=0) { */
                   5897:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5898:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5899:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5900:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5901:    /*   } */
                   5902:    /* } */
                   5903: 
                   5904:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5905:    sprintf(digit,"%-d",ij);
                   5906:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5907:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5908:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5909:    strcat(fileresprobmorprev,fileresu);
                   5910:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5911:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5912:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5913:    }
                   5914:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5915:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5916:    pstamp(ficresprobmorprev);
                   5917:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5918:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5919:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5920:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5921:    }
                   5922:    for(j=1;j<=cptcoveff;j++) 
                   5923:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5924:    fprintf(ficresprobmorprev,"\n");
                   5925: 
1.218     brouard  5926:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5927:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5928:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5929:      for(i=1; i<=nlstate;i++)
                   5930:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5931:    }  
                   5932:    fprintf(ficresprobmorprev,"\n");
                   5933:   
                   5934:    fprintf(ficgp,"\n# Routine varevsij");
                   5935:    fprintf(ficgp,"\nunset title \n");
                   5936:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5937:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5938:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  5939: 
1.218     brouard  5940:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5941:    pstamp(ficresvij);
                   5942:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5943:    if(popbased==1)
                   5944:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5945:    else
                   5946:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5947:    fprintf(ficresvij,"# Age");
                   5948:    for(i=1; i<=nlstate;i++)
                   5949:      for(j=1; j<=nlstate;j++)
                   5950:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5951:    fprintf(ficresvij,"\n");
                   5952: 
                   5953:    xp=vector(1,npar);
                   5954:    dnewm=matrix(1,nlstate,1,npar);
                   5955:    doldm=matrix(1,nlstate,1,nlstate);
                   5956:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5957:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5958: 
                   5959:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5960:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5961:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5962:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5963:   
1.218     brouard  5964:    if(estepm < stepm){
                   5965:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5966:    }
                   5967:    else  hstepm=estepm;   
                   5968:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5969:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5970:       nhstepm is the number of hstepm from age to agelim 
                   5971:       nstepm is the number of stepm from age to agelim. 
                   5972:       Look at function hpijx to understand why because of memory size limitations, 
                   5973:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5974:       survival function given by stepm (the optimization length). Unfortunately it
                   5975:       means that if the survival funtion is printed every two years of age and if
                   5976:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5977:       results. So we changed our mind and took the option of the best precision.
                   5978:    */
                   5979:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5980:    agelim = AGESUP;
                   5981:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5982:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5983:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5984:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5985:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5986:      gp=matrix(0,nhstepm,1,nlstate);
                   5987:      gm=matrix(0,nhstepm,1,nlstate);
                   5988:                
                   5989:                
                   5990:      for(theta=1; theta <=npar; theta++){
                   5991:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   5992:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5993:        }
1.279     brouard  5994:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   5995:        * returns into prlim .
1.288     brouard  5996:        */
1.242     brouard  5997:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  5998: 
                   5999:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6000:        if (popbased==1) {
                   6001:         if(mobilav ==0){
                   6002:           for(i=1; i<=nlstate;i++)
                   6003:             prlim[i][i]=probs[(int)age][i][ij];
                   6004:         }else{ /* mobilav */ 
                   6005:           for(i=1; i<=nlstate;i++)
                   6006:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6007:         }
                   6008:        }
1.279     brouard  6009:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}_x\f$ at horizon h.
                   6010:        */                      
                   6011:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292   ! brouard  6012:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6013:        * at horizon h in state j including mortality.
                   6014:        */
1.218     brouard  6015:        for(j=1; j<= nlstate; j++){
                   6016:         for(h=0; h<=nhstepm; h++){
                   6017:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6018:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6019:         }
                   6020:        }
1.279     brouard  6021:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6022:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6023:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6024:        */
                   6025:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6026:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6027:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6028:        }
                   6029:        
                   6030:        /* Again with minus shift */
1.218     brouard  6031:                        
                   6032:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6033:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6034: 
1.242     brouard  6035:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6036:                        
                   6037:        if (popbased==1) {
                   6038:         if(mobilav ==0){
                   6039:           for(i=1; i<=nlstate;i++)
                   6040:             prlim[i][i]=probs[(int)age][i][ij];
                   6041:         }else{ /* mobilav */ 
                   6042:           for(i=1; i<=nlstate;i++)
                   6043:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6044:         }
                   6045:        }
                   6046:                        
1.235     brouard  6047:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6048:                        
                   6049:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6050:         for(h=0; h<=nhstepm; h++){
                   6051:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6052:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6053:         }
                   6054:        }
                   6055:        /* This for computing probability of death (h=1 means
                   6056:          computed over hstepm matrices product = hstepm*stepm months) 
                   6057:          as a weighted average of prlim.
                   6058:        */
                   6059:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6060:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6061:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6062:        }    
1.279     brouard  6063:        /* end shifting computations */
                   6064: 
                   6065:        /**< Computing gradient matrix at horizon h 
                   6066:        */
1.218     brouard  6067:        for(j=1; j<= nlstate; j++) /* vareij */
                   6068:         for(h=0; h<=nhstepm; h++){
                   6069:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6070:         }
1.279     brouard  6071:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6072:        */
                   6073:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6074:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6075:        }
                   6076:                        
                   6077:      } /* End theta */
1.279     brouard  6078:      
                   6079:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6080:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6081:                
                   6082:      for(h=0; h<=nhstepm; h++) /* veij */
                   6083:        for(j=1; j<=nlstate;j++)
                   6084:         for(theta=1; theta <=npar; theta++)
                   6085:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6086:                
                   6087:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6088:        for(theta=1; theta <=npar; theta++)
                   6089:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6090:      /**< as well as its transposed matrix 
                   6091:       */               
1.218     brouard  6092:                
                   6093:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6094:      for(i=1;i<=nlstate;i++)
                   6095:        for(j=1;j<=nlstate;j++)
                   6096:         vareij[i][j][(int)age] =0.;
1.279     brouard  6097: 
                   6098:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6099:       * and k (nhstepm) formula 15 of article
                   6100:       * Lievre-Brouard-Heathcote
                   6101:       */
                   6102:      
1.218     brouard  6103:      for(h=0;h<=nhstepm;h++){
                   6104:        for(k=0;k<=nhstepm;k++){
                   6105:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6106:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6107:         for(i=1;i<=nlstate;i++)
                   6108:           for(j=1;j<=nlstate;j++)
                   6109:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6110:        }
                   6111:      }
                   6112:                
1.279     brouard  6113:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6114:       * p.j overall mortality formula 49 but computed directly because
                   6115:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6116:       * wix is independent of theta.
                   6117:       */
1.218     brouard  6118:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6119:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6120:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6121:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6122:         varppt[j][i]=doldmp[j][i];
                   6123:      /* end ppptj */
                   6124:      /*  x centered again */
                   6125:                
1.242     brouard  6126:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6127:                
                   6128:      if (popbased==1) {
                   6129:        if(mobilav ==0){
                   6130:         for(i=1; i<=nlstate;i++)
                   6131:           prlim[i][i]=probs[(int)age][i][ij];
                   6132:        }else{ /* mobilav */ 
                   6133:         for(i=1; i<=nlstate;i++)
                   6134:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6135:        }
                   6136:      }
                   6137:                
                   6138:      /* This for computing probability of death (h=1 means
                   6139:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6140:        as a weighted average of prlim.
                   6141:      */
1.235     brouard  6142:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6143:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6144:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6145:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6146:      }    
                   6147:      /* end probability of death */
                   6148:                
                   6149:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6150:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6151:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6152:        for(i=1; i<=nlstate;i++){
                   6153:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6154:        }
                   6155:      } 
                   6156:      fprintf(ficresprobmorprev,"\n");
                   6157:                
                   6158:      fprintf(ficresvij,"%.0f ",age );
                   6159:      for(i=1; i<=nlstate;i++)
                   6160:        for(j=1; j<=nlstate;j++){
                   6161:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6162:        }
                   6163:      fprintf(ficresvij,"\n");
                   6164:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6165:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6166:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6167:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6168:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6169:    } /* End age */
                   6170:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6171:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6172:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6173:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6174:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6175:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6176:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6177:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6178:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6179:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6180:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6181:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6182:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6183:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6184:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6185:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6186:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6187:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6188:     */
1.218     brouard  6189:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6190:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6191: 
1.218     brouard  6192:    free_vector(xp,1,npar);
                   6193:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6194:    free_matrix(dnewm,1,nlstate,1,npar);
                   6195:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6196:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6197:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6198:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6199:    fclose(ficresprobmorprev);
                   6200:    fflush(ficgp);
                   6201:    fflush(fichtm); 
                   6202:  }  /* end varevsij */
1.126     brouard  6203: 
                   6204: /************ Variance of prevlim ******************/
1.269     brouard  6205:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6206: {
1.205     brouard  6207:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6208:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6209: 
1.268     brouard  6210:   double **dnewmpar,**doldm;
1.126     brouard  6211:   int i, j, nhstepm, hstepm;
                   6212:   double *xp;
                   6213:   double *gp, *gm;
                   6214:   double **gradg, **trgradg;
1.208     brouard  6215:   double **mgm, **mgp;
1.126     brouard  6216:   double age,agelim;
                   6217:   int theta;
                   6218:   
                   6219:   pstamp(ficresvpl);
1.288     brouard  6220:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6221:   fprintf(ficresvpl,"# Age ");
                   6222:   if(nresult >=1)
                   6223:     fprintf(ficresvpl," Result# ");
1.126     brouard  6224:   for(i=1; i<=nlstate;i++)
                   6225:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6226:   fprintf(ficresvpl,"\n");
                   6227: 
                   6228:   xp=vector(1,npar);
1.268     brouard  6229:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6230:   doldm=matrix(1,nlstate,1,nlstate);
                   6231:   
                   6232:   hstepm=1*YEARM; /* Every year of age */
                   6233:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6234:   agelim = AGESUP;
                   6235:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6236:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6237:     if (stepm >= YEARM) hstepm=1;
                   6238:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6239:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6240:     mgp=matrix(1,npar,1,nlstate);
                   6241:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6242:     gp=vector(1,nlstate);
                   6243:     gm=vector(1,nlstate);
                   6244: 
                   6245:     for(theta=1; theta <=npar; theta++){
                   6246:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6247:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6248:       }
1.288     brouard  6249:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6250:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6251:       /* else */
                   6252:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6253:       for(i=1;i<=nlstate;i++){
1.126     brouard  6254:        gp[i] = prlim[i][i];
1.208     brouard  6255:        mgp[theta][i] = prlim[i][i];
                   6256:       }
1.126     brouard  6257:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6258:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6259:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6260:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6261:       /* else */
                   6262:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6263:       for(i=1;i<=nlstate;i++){
1.126     brouard  6264:        gm[i] = prlim[i][i];
1.208     brouard  6265:        mgm[theta][i] = prlim[i][i];
                   6266:       }
1.126     brouard  6267:       for(i=1;i<=nlstate;i++)
                   6268:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6269:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6270:     } /* End theta */
                   6271: 
                   6272:     trgradg =matrix(1,nlstate,1,npar);
                   6273: 
                   6274:     for(j=1; j<=nlstate;j++)
                   6275:       for(theta=1; theta <=npar; theta++)
                   6276:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6277:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6278:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6279:     /*   for(j=1; j<=nlstate;j++){ */
                   6280:     /*         printf(" %d ",j); */
                   6281:     /*         for(theta=1; theta <=npar; theta++) */
                   6282:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6283:     /*         printf("\n "); */
                   6284:     /*   } */
                   6285:     /* } */
                   6286:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6287:     /*   printf("\n gradg %d ",(int)age); */
                   6288:     /*   for(j=1; j<=nlstate;j++){ */
                   6289:     /*         printf("%d ",j); */
                   6290:     /*         for(theta=1; theta <=npar; theta++) */
                   6291:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6292:     /*         printf("\n "); */
                   6293:     /*   } */
                   6294:     /* } */
1.126     brouard  6295: 
                   6296:     for(i=1;i<=nlstate;i++)
                   6297:       varpl[i][(int)age] =0.;
1.209     brouard  6298:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6299:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6300:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6301:     }else{
1.268     brouard  6302:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6303:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6304:     }
1.126     brouard  6305:     for(i=1;i<=nlstate;i++)
                   6306:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6307: 
                   6308:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6309:     if(nresult >=1)
                   6310:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6311:     for(i=1; i<=nlstate;i++){
1.126     brouard  6312:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6313:       /* for(j=1;j<=nlstate;j++) */
                   6314:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6315:     }
1.126     brouard  6316:     fprintf(ficresvpl,"\n");
                   6317:     free_vector(gp,1,nlstate);
                   6318:     free_vector(gm,1,nlstate);
1.208     brouard  6319:     free_matrix(mgm,1,npar,1,nlstate);
                   6320:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6321:     free_matrix(gradg,1,npar,1,nlstate);
                   6322:     free_matrix(trgradg,1,nlstate,1,npar);
                   6323:   } /* End age */
                   6324: 
                   6325:   free_vector(xp,1,npar);
                   6326:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6327:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6328: 
                   6329: }
                   6330: 
                   6331: 
                   6332: /************ Variance of backprevalence limit ******************/
1.269     brouard  6333:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6334: {
                   6335:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6336:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6337: 
                   6338:   double **dnewmpar,**doldm;
                   6339:   int i, j, nhstepm, hstepm;
                   6340:   double *xp;
                   6341:   double *gp, *gm;
                   6342:   double **gradg, **trgradg;
                   6343:   double **mgm, **mgp;
                   6344:   double age,agelim;
                   6345:   int theta;
                   6346:   
                   6347:   pstamp(ficresvbl);
                   6348:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6349:   fprintf(ficresvbl,"# Age ");
                   6350:   if(nresult >=1)
                   6351:     fprintf(ficresvbl," Result# ");
                   6352:   for(i=1; i<=nlstate;i++)
                   6353:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6354:   fprintf(ficresvbl,"\n");
                   6355: 
                   6356:   xp=vector(1,npar);
                   6357:   dnewmpar=matrix(1,nlstate,1,npar);
                   6358:   doldm=matrix(1,nlstate,1,nlstate);
                   6359:   
                   6360:   hstepm=1*YEARM; /* Every year of age */
                   6361:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6362:   agelim = AGEINF;
                   6363:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6364:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6365:     if (stepm >= YEARM) hstepm=1;
                   6366:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6367:     gradg=matrix(1,npar,1,nlstate);
                   6368:     mgp=matrix(1,npar,1,nlstate);
                   6369:     mgm=matrix(1,npar,1,nlstate);
                   6370:     gp=vector(1,nlstate);
                   6371:     gm=vector(1,nlstate);
                   6372: 
                   6373:     for(theta=1; theta <=npar; theta++){
                   6374:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6375:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6376:       }
                   6377:       if(mobilavproj > 0 )
                   6378:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6379:       else
                   6380:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6381:       for(i=1;i<=nlstate;i++){
                   6382:        gp[i] = bprlim[i][i];
                   6383:        mgp[theta][i] = bprlim[i][i];
                   6384:       }
                   6385:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6386:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6387:        if(mobilavproj > 0 )
                   6388:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6389:        else
                   6390:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6391:       for(i=1;i<=nlstate;i++){
                   6392:        gm[i] = bprlim[i][i];
                   6393:        mgm[theta][i] = bprlim[i][i];
                   6394:       }
                   6395:       for(i=1;i<=nlstate;i++)
                   6396:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6397:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6398:     } /* End theta */
                   6399: 
                   6400:     trgradg =matrix(1,nlstate,1,npar);
                   6401: 
                   6402:     for(j=1; j<=nlstate;j++)
                   6403:       for(theta=1; theta <=npar; theta++)
                   6404:        trgradg[j][theta]=gradg[theta][j];
                   6405:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6406:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6407:     /*   for(j=1; j<=nlstate;j++){ */
                   6408:     /*         printf(" %d ",j); */
                   6409:     /*         for(theta=1; theta <=npar; theta++) */
                   6410:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6411:     /*         printf("\n "); */
                   6412:     /*   } */
                   6413:     /* } */
                   6414:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6415:     /*   printf("\n gradg %d ",(int)age); */
                   6416:     /*   for(j=1; j<=nlstate;j++){ */
                   6417:     /*         printf("%d ",j); */
                   6418:     /*         for(theta=1; theta <=npar; theta++) */
                   6419:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6420:     /*         printf("\n "); */
                   6421:     /*   } */
                   6422:     /* } */
                   6423: 
                   6424:     for(i=1;i<=nlstate;i++)
                   6425:       varbpl[i][(int)age] =0.;
                   6426:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6427:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6428:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6429:     }else{
                   6430:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6431:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6432:     }
                   6433:     for(i=1;i<=nlstate;i++)
                   6434:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6435: 
                   6436:     fprintf(ficresvbl,"%.0f ",age );
                   6437:     if(nresult >=1)
                   6438:       fprintf(ficresvbl,"%d ",nres );
                   6439:     for(i=1; i<=nlstate;i++)
                   6440:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6441:     fprintf(ficresvbl,"\n");
                   6442:     free_vector(gp,1,nlstate);
                   6443:     free_vector(gm,1,nlstate);
                   6444:     free_matrix(mgm,1,npar,1,nlstate);
                   6445:     free_matrix(mgp,1,npar,1,nlstate);
                   6446:     free_matrix(gradg,1,npar,1,nlstate);
                   6447:     free_matrix(trgradg,1,nlstate,1,npar);
                   6448:   } /* End age */
                   6449: 
                   6450:   free_vector(xp,1,npar);
                   6451:   free_matrix(doldm,1,nlstate,1,npar);
                   6452:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6453: 
                   6454: }
                   6455: 
                   6456: /************ Variance of one-step probabilities  ******************/
                   6457: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6458:  {
                   6459:    int i, j=0,  k1, l1, tj;
                   6460:    int k2, l2, j1,  z1;
                   6461:    int k=0, l;
                   6462:    int first=1, first1, first2;
                   6463:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6464:    double **dnewm,**doldm;
                   6465:    double *xp;
                   6466:    double *gp, *gm;
                   6467:    double **gradg, **trgradg;
                   6468:    double **mu;
                   6469:    double age, cov[NCOVMAX+1];
                   6470:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6471:    int theta;
                   6472:    char fileresprob[FILENAMELENGTH];
                   6473:    char fileresprobcov[FILENAMELENGTH];
                   6474:    char fileresprobcor[FILENAMELENGTH];
                   6475:    double ***varpij;
                   6476: 
                   6477:    strcpy(fileresprob,"PROB_"); 
                   6478:    strcat(fileresprob,fileres);
                   6479:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6480:      printf("Problem with resultfile: %s\n", fileresprob);
                   6481:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6482:    }
                   6483:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6484:    strcat(fileresprobcov,fileresu);
                   6485:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6486:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6487:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6488:    }
                   6489:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6490:    strcat(fileresprobcor,fileresu);
                   6491:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6492:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6493:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6494:    }
                   6495:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6496:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6497:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6498:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6499:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6500:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6501:    pstamp(ficresprob);
                   6502:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6503:    fprintf(ficresprob,"# Age");
                   6504:    pstamp(ficresprobcov);
                   6505:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6506:    fprintf(ficresprobcov,"# Age");
                   6507:    pstamp(ficresprobcor);
                   6508:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6509:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6510: 
                   6511: 
1.222     brouard  6512:    for(i=1; i<=nlstate;i++)
                   6513:      for(j=1; j<=(nlstate+ndeath);j++){
                   6514:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6515:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6516:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6517:      }  
                   6518:    /* fprintf(ficresprob,"\n");
                   6519:       fprintf(ficresprobcov,"\n");
                   6520:       fprintf(ficresprobcor,"\n");
                   6521:    */
                   6522:    xp=vector(1,npar);
                   6523:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6524:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6525:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6526:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6527:    first=1;
                   6528:    fprintf(ficgp,"\n# Routine varprob");
                   6529:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6530:    fprintf(fichtm,"\n");
                   6531: 
1.288     brouard  6532:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6533:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6534:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6535: and drawn. It helps understanding how is the covariance between two incidences.\
                   6536:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6537:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6538: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6539: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6540: standard deviations wide on each axis. <br>\
                   6541:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6542:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6543: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6544: 
1.222     brouard  6545:    cov[1]=1;
                   6546:    /* tj=cptcoveff; */
1.225     brouard  6547:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6548:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6549:    j1=0;
1.224     brouard  6550:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6551:      if  (cptcovn>0) {
                   6552:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6553:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6554:        fprintf(ficresprob, "**********\n#\n");
                   6555:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6556:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6557:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6558:                        
1.222     brouard  6559:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6560:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6561:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6562:                        
                   6563:                        
1.222     brouard  6564:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6565:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6566:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6567:                        
1.222     brouard  6568:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6569:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6570:        fprintf(ficresprobcor, "**********\n#");    
                   6571:        if(invalidvarcomb[j1]){
                   6572:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6573:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6574:         continue;
                   6575:        }
                   6576:      }
                   6577:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6578:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6579:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6580:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6581:      for (age=bage; age<=fage; age ++){ 
                   6582:        cov[2]=age;
                   6583:        if(nagesqr==1)
                   6584:         cov[3]= age*age;
                   6585:        for (k=1; k<=cptcovn;k++) {
                   6586:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6587:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6588:                                                                    * 1  1 1 1 1
                   6589:                                                                    * 2  2 1 1 1
                   6590:                                                                    * 3  1 2 1 1
                   6591:                                                                    */
                   6592:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6593:        }
                   6594:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6595:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6596:        for (k=1; k<=cptcovprod;k++)
                   6597:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6598:                        
                   6599:                        
1.222     brouard  6600:        for(theta=1; theta <=npar; theta++){
                   6601:         for(i=1; i<=npar; i++)
                   6602:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6603:                                
1.222     brouard  6604:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6605:                                
1.222     brouard  6606:         k=0;
                   6607:         for(i=1; i<= (nlstate); i++){
                   6608:           for(j=1; j<=(nlstate+ndeath);j++){
                   6609:             k=k+1;
                   6610:             gp[k]=pmmij[i][j];
                   6611:           }
                   6612:         }
1.220     brouard  6613:                                
1.222     brouard  6614:         for(i=1; i<=npar; i++)
                   6615:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6616:                                
1.222     brouard  6617:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6618:         k=0;
                   6619:         for(i=1; i<=(nlstate); i++){
                   6620:           for(j=1; j<=(nlstate+ndeath);j++){
                   6621:             k=k+1;
                   6622:             gm[k]=pmmij[i][j];
                   6623:           }
                   6624:         }
1.220     brouard  6625:                                
1.222     brouard  6626:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6627:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6628:        }
1.126     brouard  6629: 
1.222     brouard  6630:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6631:         for(theta=1; theta <=npar; theta++)
                   6632:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6633:                        
1.222     brouard  6634:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6635:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6636:                        
1.222     brouard  6637:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6638:                        
1.222     brouard  6639:        k=0;
                   6640:        for(i=1; i<=(nlstate); i++){
                   6641:         for(j=1; j<=(nlstate+ndeath);j++){
                   6642:           k=k+1;
                   6643:           mu[k][(int) age]=pmmij[i][j];
                   6644:         }
                   6645:        }
                   6646:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6647:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6648:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6649:                        
1.222     brouard  6650:        /*printf("\n%d ",(int)age);
                   6651:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6652:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6653:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6654:         }*/
1.220     brouard  6655:                        
1.222     brouard  6656:        fprintf(ficresprob,"\n%d ",(int)age);
                   6657:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6658:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6659:                        
1.222     brouard  6660:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6661:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6662:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6663:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6664:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6665:        }
                   6666:        i=0;
                   6667:        for (k=1; k<=(nlstate);k++){
                   6668:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6669:           i++;
                   6670:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6671:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6672:           for (j=1; j<=i;j++){
                   6673:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6674:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6675:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6676:           }
                   6677:         }
                   6678:        }/* end of loop for state */
                   6679:      } /* end of loop for age */
                   6680:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6681:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6682:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6683:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6684:     
                   6685:      /* Confidence intervalle of pij  */
                   6686:      /*
                   6687:        fprintf(ficgp,"\nunset parametric;unset label");
                   6688:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6689:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6690:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6691:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6692:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6693:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6694:      */
                   6695:                
                   6696:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6697:      first1=1;first2=2;
                   6698:      for (k2=1; k2<=(nlstate);k2++){
                   6699:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6700:         if(l2==k2) continue;
                   6701:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6702:         for (k1=1; k1<=(nlstate);k1++){
                   6703:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6704:             if(l1==k1) continue;
                   6705:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6706:             if(i<=j) continue;
                   6707:             for (age=bage; age<=fage; age ++){ 
                   6708:               if ((int)age %5==0){
                   6709:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6710:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6711:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6712:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6713:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6714:                 c12=cv12/sqrt(v1*v2);
                   6715:                 /* Computing eigen value of matrix of covariance */
                   6716:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6717:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6718:                 if ((lc2 <0) || (lc1 <0) ){
                   6719:                   if(first2==1){
                   6720:                     first1=0;
                   6721:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6722:                   }
                   6723:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6724:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6725:                   /* lc2=fabs(lc2); */
                   6726:                 }
1.220     brouard  6727:                                                                
1.222     brouard  6728:                 /* Eigen vectors */
1.280     brouard  6729:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6730:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6731:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6732:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6733:                 }else
                   6734:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6735:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6736:                 v21=(lc1-v1)/cv12*v11;
                   6737:                 v12=-v21;
                   6738:                 v22=v11;
                   6739:                 tnalp=v21/v11;
                   6740:                 if(first1==1){
                   6741:                   first1=0;
                   6742:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6743:                 }
                   6744:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6745:                 /*printf(fignu*/
                   6746:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6747:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6748:                 if(first==1){
                   6749:                   first=0;
                   6750:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6751:                   fprintf(ficgp,"\nset parametric;unset label");
                   6752:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6753:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6754:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6755:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6756: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6757:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6758:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6759:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6760:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6761:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6762:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6763:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6764:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6765:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6766:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6767:                 }else{
                   6768:                   first=0;
                   6769:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6770:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6771:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6772:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6773:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6774:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6775:                 }/* if first */
                   6776:               } /* age mod 5 */
                   6777:             } /* end loop age */
                   6778:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6779:             first=1;
                   6780:           } /*l12 */
                   6781:         } /* k12 */
                   6782:        } /*l1 */
                   6783:      }/* k1 */
                   6784:    }  /* loop on combination of covariates j1 */
                   6785:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6786:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6787:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6788:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6789:    free_vector(xp,1,npar);
                   6790:    fclose(ficresprob);
                   6791:    fclose(ficresprobcov);
                   6792:    fclose(ficresprobcor);
                   6793:    fflush(ficgp);
                   6794:    fflush(fichtmcov);
                   6795:  }
1.126     brouard  6796: 
                   6797: 
                   6798: /******************* Printing html file ***********/
1.201     brouard  6799: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6800:                  int lastpass, int stepm, int weightopt, char model[],\
                   6801:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6802:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.273     brouard  6803:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateproj1, double dateback1, \
                   6804:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateproj2, double dateback2){
1.237     brouard  6805:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6806: 
                   6807:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6808:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6809: </ul>");
1.237     brouard  6810:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6811: </ul>", model);
1.214     brouard  6812:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6813:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6814:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6815:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6816:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6817:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6818:    fprintf(fichtm,"\
                   6819:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6820:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6821:    fprintf(fichtm,"\
1.217     brouard  6822:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6823:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6824:    fprintf(fichtm,"\
1.288     brouard  6825:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6826:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6827:    fprintf(fichtm,"\
1.288     brouard  6828:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  6829:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6830:    fprintf(fichtm,"\
1.211     brouard  6831:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6832:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6833:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6834:    if(prevfcast==1){
                   6835:      fprintf(fichtm,"\
                   6836:  - Prevalence projections by age and states:                           \
1.201     brouard  6837:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6838:    }
1.126     brouard  6839: 
                   6840: 
1.225     brouard  6841:    m=pow(2,cptcoveff);
1.222     brouard  6842:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6843: 
1.264     brouard  6844:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6845: 
                   6846:    jj1=0;
                   6847: 
                   6848:    fprintf(fichtm," \n<ul>");
                   6849:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6850:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6851:      if(m != 1 && TKresult[nres]!= k1)
                   6852:        continue;
                   6853:      jj1++;
                   6854:      if (cptcovn > 0) {
                   6855:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6856:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6857:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6858:        }
                   6859:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6860:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6861:        }
                   6862:        fprintf(fichtm,"\">");
                   6863:        
                   6864:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6865:        fprintf(fichtm,"************ Results for covariates");
                   6866:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6867:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6868:        }
                   6869:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6870:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6871:        }
                   6872:        if(invalidvarcomb[k1]){
                   6873:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6874:         continue;
                   6875:        }
                   6876:        fprintf(fichtm,"</a></li>");
                   6877:      } /* cptcovn >0 */
                   6878:    }
                   6879:      fprintf(fichtm," \n</ul>");
                   6880: 
1.222     brouard  6881:    jj1=0;
1.237     brouard  6882: 
                   6883:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6884:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6885:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6886:        continue;
1.220     brouard  6887: 
1.222     brouard  6888:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6889:      jj1++;
                   6890:      if (cptcovn > 0) {
1.264     brouard  6891:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6892:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6893:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6894:        }
                   6895:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6896:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6897:        }
                   6898:        fprintf(fichtm,"\"</a>");
                   6899:  
1.222     brouard  6900:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6901:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6902:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6903:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6904:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6905:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6906:        }
1.237     brouard  6907:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6908:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6909:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6910:       }
                   6911:        
1.230     brouard  6912:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6913:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6914:        if(invalidvarcomb[k1]){
                   6915:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6916:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6917:         continue;
                   6918:        }
                   6919:      }
                   6920:      /* aij, bij */
1.259     brouard  6921:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6922: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6923:      /* Pij */
1.241     brouard  6924:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6925: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6926:      /* Quasi-incidences */
                   6927:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6928:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6929:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6930: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6931: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6932:      /* Survival functions (period) in state j */
                   6933:      for(cpt=1; cpt<=nlstate;cpt++){
1.292   ! brouard  6934:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6935: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6936:      }
                   6937:      /* State specific survival functions (period) */
                   6938:      for(cpt=1; cpt<=nlstate;cpt++){
1.292   ! brouard  6939:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
        !          6940:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  6941:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6942:      }
1.288     brouard  6943:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  6944:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6945:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6946: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6947:      }
                   6948:      if(backcast==1){
1.288     brouard  6949:        /* Backward prevalence in each health state */
1.222     brouard  6950:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6951:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6952: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6953:        }
1.217     brouard  6954:      }
1.222     brouard  6955:      if(prevfcast==1){
1.288     brouard  6956:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  6957:        for(cpt=1; cpt<=nlstate;cpt++){
1.288     brouard  6958:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.273     brouard  6959: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateproj1, dateproj2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6960:        }
                   6961:      }
1.268     brouard  6962:      if(backcast==1){
                   6963:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6964:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6965:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   6966:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   6967:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   6968: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6969:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  6970:        }
                   6971:      }
1.220     brouard  6972:         
1.222     brouard  6973:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6974:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6975: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6976:      }
                   6977:      /* } /\* end i1 *\/ */
                   6978:    }/* End k1 */
                   6979:    fprintf(fichtm,"</ul>");
1.126     brouard  6980: 
1.222     brouard  6981:    fprintf(fichtm,"\
1.126     brouard  6982: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6983:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6984:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6985: But because parameters are usually highly correlated (a higher incidence of disability \
                   6986: and a higher incidence of recovery can give very close observed transition) it might \
                   6987: be very useful to look not only at linear confidence intervals estimated from the \
                   6988: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6989: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6990: covariance matrix of the one-step probabilities. \
                   6991: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  6992: 
1.222     brouard  6993:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   6994:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   6995:    fprintf(fichtm,"\
1.126     brouard  6996:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  6997:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  6998: 
1.222     brouard  6999:    fprintf(fichtm,"\
1.126     brouard  7000:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7001:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7002:    fprintf(fichtm,"\
1.126     brouard  7003:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7004:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7005:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7006:    fprintf(fichtm,"\
1.126     brouard  7007:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7008:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7009:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7010:    fprintf(fichtm,"\
1.288     brouard  7011:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7012:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7013:    fprintf(fichtm,"\
1.128     brouard  7014:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7015:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7016:    fprintf(fichtm,"\
1.288     brouard  7017:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7018:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7019: 
                   7020: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7021: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7022: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7023: /*     <br>",fileres,fileres,fileres,fileres); */
                   7024: /*  else  */
                   7025: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7026:    fflush(fichtm);
                   7027:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7028: 
1.225     brouard  7029:    m=pow(2,cptcoveff);
1.222     brouard  7030:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7031: 
1.222     brouard  7032:    jj1=0;
1.237     brouard  7033: 
1.241     brouard  7034:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7035:    for(k1=1; k1<=m;k1++){
1.253     brouard  7036:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7037:        continue;
1.222     brouard  7038:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7039:      jj1++;
1.126     brouard  7040:      if (cptcovn > 0) {
                   7041:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7042:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7043:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7044:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7045:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7046:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7047:       }
                   7048: 
1.126     brouard  7049:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7050: 
1.222     brouard  7051:        if(invalidvarcomb[k1]){
                   7052:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7053:         continue;
                   7054:        }
1.126     brouard  7055:      }
                   7056:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7057:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7058: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7059: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7060:      }
                   7061:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7062: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7063: true period expectancies (those weighted with period prevalences are also\
                   7064:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7065:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7066: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7067:      /* } /\* end i1 *\/ */
                   7068:    }/* End k1 */
1.241     brouard  7069:   }/* End nres */
1.222     brouard  7070:    fprintf(fichtm,"</ul>");
                   7071:    fflush(fichtm);
1.126     brouard  7072: }
                   7073: 
                   7074: /******************* Gnuplot file **************/
1.270     brouard  7075: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7076: 
                   7077:   char dirfileres[132],optfileres[132];
1.264     brouard  7078:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7079:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7080:   int lv=0, vlv=0, kl=0;
1.130     brouard  7081:   int ng=0;
1.201     brouard  7082:   int vpopbased;
1.223     brouard  7083:   int ioffset; /* variable offset for columns */
1.270     brouard  7084:   int iyearc=1; /* variable column for year of projection  */
                   7085:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7086:   int nres=0; /* Index of resultline */
1.266     brouard  7087:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7088: 
1.126     brouard  7089: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7090: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7091: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7092: /*   } */
                   7093: 
                   7094:   /*#ifdef windows */
                   7095:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7096:   /*#endif */
1.225     brouard  7097:   m=pow(2,cptcoveff);
1.126     brouard  7098: 
1.274     brouard  7099:   /* diagram of the model */
                   7100:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7101:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7102:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7103:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7104: 
                   7105:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7106:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7107:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7108:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7109:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7110:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7111:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7112: 
1.202     brouard  7113:   /* Contribution to likelihood */
                   7114:   /* Plot the probability implied in the likelihood */
1.223     brouard  7115:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7116:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7117:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7118:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7119: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7120:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7121: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7122:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7123:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7124:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7125:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7126:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7127:   for (i=1; i<= nlstate ; i ++) {
                   7128:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7129:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7130:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7131:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7132:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7133:     }
                   7134:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7135:   }
                   7136:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7137:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7138:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7139:   fprintf(ficgp,"\nset out;unset log\n");
                   7140:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7141: 
1.126     brouard  7142:   strcpy(dirfileres,optionfilefiname);
                   7143:   strcpy(optfileres,"vpl");
1.223     brouard  7144:   /* 1eme*/
1.238     brouard  7145:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7146:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7147:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7148:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7149:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7150:          continue;
                   7151:        /* We are interested in selected combination by the resultline */
1.246     brouard  7152:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7153:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7154:        strcpy(gplotlabel,"(");
1.238     brouard  7155:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7156:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7157:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7158:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7159:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7160:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7161:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7162:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7163:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7164:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7165:        }
                   7166:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7167:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7168:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7169:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7170:        }
                   7171:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7172:        /* printf("\n#\n"); */
1.238     brouard  7173:        fprintf(ficgp,"\n#\n");
                   7174:        if(invalidvarcomb[k1]){
1.260     brouard  7175:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7176:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7177:          continue;
                   7178:        }
1.235     brouard  7179:       
1.241     brouard  7180:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7181:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7182:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7183:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7184:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7185:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7186:       /* k1-1 error should be nres-1*/
1.238     brouard  7187:        for (i=1; i<= nlstate ; i ++) {
                   7188:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7189:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7190:        }
1.288     brouard  7191:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7192:        for (i=1; i<= nlstate ; i ++) {
                   7193:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7194:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7195:        } 
1.260     brouard  7196:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7197:        for (i=1; i<= nlstate ; i ++) {
                   7198:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7199:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7200:        }  
1.265     brouard  7201:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7202:        
                   7203:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7204:         if(cptcoveff ==0){
1.271     brouard  7205:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7206:        }else{
                   7207:          kl=0;
                   7208:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7209:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7210:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7211:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7212:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7213:            vlv= nbcode[Tvaraff[k]][lv];
                   7214:            kl++;
                   7215:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7216:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7217:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7218:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7219:            if(k==cptcoveff){
                   7220:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7221:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7222:            }else{
                   7223:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7224:              kl++;
                   7225:            }
                   7226:          } /* end covariate */
                   7227:        } /* end if no covariate */
                   7228: 
1.238     brouard  7229:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7230:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7231:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7232:          if(cptcoveff ==0){
1.245     brouard  7233:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7234:          }else{
                   7235:            kl=0;
                   7236:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7237:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7238:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7239:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7240:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7241:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7242:              kl++;
1.238     brouard  7243:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7244:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7245:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7246:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7247:              if(k==cptcoveff){
1.245     brouard  7248:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7249:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7250:              }else{
                   7251:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7252:                kl++;
                   7253:              }
                   7254:            } /* end covariate */
                   7255:          } /* end if no covariate */
1.268     brouard  7256:          if(backcast == 1){
                   7257:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7258:            /* k1-1 error should be nres-1*/
                   7259:            for (i=1; i<= nlstate ; i ++) {
                   7260:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7261:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7262:            }
1.271     brouard  7263:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7264:            for (i=1; i<= nlstate ; i ++) {
                   7265:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7266:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7267:            } 
1.276     brouard  7268:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7269:            for (i=1; i<= nlstate ; i ++) {
                   7270:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7271:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7272:            } 
1.274     brouard  7273:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7274:          } /* end if backprojcast */
1.238     brouard  7275:        } /* end if backcast */
1.276     brouard  7276:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7277:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7278:       } /* nres */
1.201     brouard  7279:     } /* k1 */
                   7280:   } /* cpt */
1.235     brouard  7281: 
                   7282:   
1.126     brouard  7283:   /*2 eme*/
1.238     brouard  7284:   for (k1=1; k1<= m ; k1 ++){  
                   7285:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7286:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7287:        continue;
                   7288:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7289:       strcpy(gplotlabel,"(");
1.238     brouard  7290:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7291:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7292:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7293:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7294:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7295:        vlv= nbcode[Tvaraff[k]][lv];
                   7296:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7297:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7298:       }
1.237     brouard  7299:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7300:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7301:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7302:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7303:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7304:       }
1.264     brouard  7305:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7306:       fprintf(ficgp,"\n#\n");
1.223     brouard  7307:       if(invalidvarcomb[k1]){
                   7308:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7309:        continue;
                   7310:       }
1.219     brouard  7311:                        
1.241     brouard  7312:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7313:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7314:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7315:        if(vpopbased==0){
1.238     brouard  7316:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7317:        }else
1.238     brouard  7318:          fprintf(ficgp,"\nreplot ");
                   7319:        for (i=1; i<= nlstate+1 ; i ++) {
                   7320:          k=2*i;
1.261     brouard  7321:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7322:          for (j=1; j<= nlstate+1 ; j ++) {
                   7323:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7324:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7325:          }   
                   7326:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7327:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7328:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7329:          for (j=1; j<= nlstate+1 ; j ++) {
                   7330:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7331:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7332:          }   
                   7333:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7334:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7335:          for (j=1; j<= nlstate+1 ; j ++) {
                   7336:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7337:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7338:          }   
                   7339:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7340:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7341:        } /* state */
                   7342:       } /* vpopbased */
1.264     brouard  7343:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7344:     } /* end nres */
                   7345:   } /* k1 end 2 eme*/
                   7346:        
                   7347:        
                   7348:   /*3eme*/
                   7349:   for (k1=1; k1<= m ; k1 ++){
                   7350:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7351:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7352:        continue;
                   7353: 
                   7354:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7355:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7356:        strcpy(gplotlabel,"(");
1.238     brouard  7357:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7358:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7359:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7360:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7361:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7362:          vlv= nbcode[Tvaraff[k]][lv];
                   7363:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7364:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7365:        }
                   7366:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7367:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7368:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7369:        }       
1.264     brouard  7370:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7371:        fprintf(ficgp,"\n#\n");
                   7372:        if(invalidvarcomb[k1]){
                   7373:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7374:          continue;
                   7375:        }
                   7376:                        
                   7377:        /*       k=2+nlstate*(2*cpt-2); */
                   7378:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7379:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7380:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7381:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7382: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7383:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7384:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7385:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7386:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7387:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7388:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7389:                                
1.238     brouard  7390:        */
                   7391:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7392:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7393:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7394:                                
1.238     brouard  7395:        } 
1.261     brouard  7396:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7397:       }
1.264     brouard  7398:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7399:     } /* end nres */
                   7400:   } /* end kl 3eme */
1.126     brouard  7401:   
1.223     brouard  7402:   /* 4eme */
1.201     brouard  7403:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7404:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7405:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7406:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7407:        continue;
1.238     brouard  7408:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7409:        strcpy(gplotlabel,"(");
1.238     brouard  7410:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7411:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7412:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7413:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7414:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7415:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7416:          vlv= nbcode[Tvaraff[k]][lv];
                   7417:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7418:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7419:        }
                   7420:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7421:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7422:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7423:        }       
1.264     brouard  7424:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7425:        fprintf(ficgp,"\n#\n");
                   7426:        if(invalidvarcomb[k1]){
                   7427:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7428:          continue;
1.223     brouard  7429:        }
1.238     brouard  7430:       
1.241     brouard  7431:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7432:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7433:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7434: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7435:        k=3;
                   7436:        for (i=1; i<= nlstate ; i ++){
                   7437:          if(i==1){
                   7438:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7439:          }else{
                   7440:            fprintf(ficgp,", '' ");
                   7441:          }
                   7442:          l=(nlstate+ndeath)*(i-1)+1;
                   7443:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7444:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7445:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7446:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7447:        } /* nlstate */
1.264     brouard  7448:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7449:       } /* end cpt state*/ 
                   7450:     } /* end nres */
                   7451:   } /* end covariate k1 */  
                   7452: 
1.220     brouard  7453: /* 5eme */
1.201     brouard  7454:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7455:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7456:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7457:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7458:        continue;
1.238     brouard  7459:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7460:        strcpy(gplotlabel,"(");
1.238     brouard  7461:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7462:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7463:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7464:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7465:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7466:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7467:          vlv= nbcode[Tvaraff[k]][lv];
                   7468:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7469:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7470:        }
                   7471:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7472:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7473:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7474:        }       
1.264     brouard  7475:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7476:        fprintf(ficgp,"\n#\n");
                   7477:        if(invalidvarcomb[k1]){
                   7478:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7479:          continue;
                   7480:        }
1.227     brouard  7481:       
1.241     brouard  7482:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7483:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7484:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7485: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7486:        k=3;
                   7487:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7488:          if(j==1)
                   7489:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7490:          else
                   7491:            fprintf(ficgp,", '' ");
                   7492:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7493:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7494:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7495:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7496:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7497:        } /* nlstate */
                   7498:        fprintf(ficgp,", '' ");
                   7499:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7500:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7501:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7502:          if(j < nlstate)
                   7503:            fprintf(ficgp,"$%d +",k+l);
                   7504:          else
                   7505:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7506:        }
1.264     brouard  7507:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7508:       } /* end cpt state*/ 
                   7509:     } /* end covariate */  
                   7510:   } /* end nres */
1.227     brouard  7511:   
1.220     brouard  7512: /* 6eme */
1.202     brouard  7513:   /* CV preval stable (period) for each covariate */
1.237     brouard  7514:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7515:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7516:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7517:       continue;
1.255     brouard  7518:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7519:       strcpy(gplotlabel,"(");      
1.288     brouard  7520:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7521:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7522:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7523:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7524:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7525:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7526:        vlv= nbcode[Tvaraff[k]][lv];
                   7527:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7528:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7529:       }
1.237     brouard  7530:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7531:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7532:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7533:       }        
1.264     brouard  7534:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7535:       fprintf(ficgp,"\n#\n");
1.223     brouard  7536:       if(invalidvarcomb[k1]){
1.227     brouard  7537:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7538:        continue;
1.223     brouard  7539:       }
1.227     brouard  7540:       
1.241     brouard  7541:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7542:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7543:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7544: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7545:       k=3; /* Offset */
1.255     brouard  7546:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7547:        if(i==1)
                   7548:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7549:        else
                   7550:          fprintf(ficgp,", '' ");
1.255     brouard  7551:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7552:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7553:        for (j=2; j<= nlstate ; j ++)
                   7554:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7555:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7556:       } /* nlstate */
1.264     brouard  7557:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7558:     } /* end cpt state*/ 
                   7559:   } /* end covariate */  
1.227     brouard  7560:   
                   7561:   
1.220     brouard  7562: /* 7eme */
1.218     brouard  7563:   if(backcast == 1){
1.288     brouard  7564:     /* CV backward prevalence  for each covariate */
1.237     brouard  7565:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7566:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7567:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7568:        continue;
1.268     brouard  7569:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7570:        strcpy(gplotlabel,"(");      
1.288     brouard  7571:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7572:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7573:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7574:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7575:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7576:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7577:          vlv= nbcode[Tvaraff[k]][lv];
                   7578:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7579:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7580:        }
1.237     brouard  7581:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7582:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7583:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7584:        }       
1.264     brouard  7585:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7586:        fprintf(ficgp,"\n#\n");
                   7587:        if(invalidvarcomb[k1]){
                   7588:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7589:          continue;
                   7590:        }
                   7591:        
1.241     brouard  7592:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7593:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7594:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7595: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7596:        k=3; /* Offset */
1.268     brouard  7597:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7598:          if(i==1)
                   7599:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7600:          else
                   7601:            fprintf(ficgp,", '' ");
                   7602:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7603:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7604:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7605:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7606:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7607:          /* for (j=2; j<= nlstate ; j ++) */
                   7608:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7609:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7610:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7611:        } /* nlstate */
1.264     brouard  7612:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7613:       } /* end cpt state*/ 
                   7614:     } /* end covariate */  
                   7615:   } /* End if backcast */
                   7616:   
1.223     brouard  7617:   /* 8eme */
1.218     brouard  7618:   if(prevfcast==1){
1.288     brouard  7619:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7620:     
1.237     brouard  7621:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7622:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7623:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7624:        continue;
1.211     brouard  7625:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7626:        strcpy(gplotlabel,"(");      
1.288     brouard  7627:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7628:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7629:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7630:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7631:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7632:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7633:          vlv= nbcode[Tvaraff[k]][lv];
                   7634:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7635:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7636:        }
1.237     brouard  7637:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7638:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7639:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7640:        }       
1.264     brouard  7641:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7642:        fprintf(ficgp,"\n#\n");
                   7643:        if(invalidvarcomb[k1]){
                   7644:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7645:          continue;
                   7646:        }
                   7647:        
                   7648:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7649:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7650:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7651:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7652: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7653: 
                   7654:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7655:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7656:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7657:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7658:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7659:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7660:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7661:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7662:          if(i==istart){
1.227     brouard  7663:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7664:          }else{
                   7665:            fprintf(ficgp,",\\\n '' ");
                   7666:          }
                   7667:          if(cptcoveff ==0){ /* No covariate */
                   7668:            ioffset=2; /* Age is in 2 */
                   7669:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7670:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7671:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7672:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7673:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7674:            if(i==nlstate+1){
1.270     brouard  7675:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7676:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7677:              fprintf(ficgp,",\\\n '' ");
                   7678:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7679:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7680:                     offyear,                           \
1.268     brouard  7681:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7682:            }else
1.227     brouard  7683:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7684:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7685:          }else{ /* more than 2 covariates */
1.270     brouard  7686:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7687:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7688:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7689:            iyearc=ioffset-1;
                   7690:            iagec=ioffset;
1.227     brouard  7691:            fprintf(ficgp," u %d:(",ioffset); 
                   7692:            kl=0;
                   7693:            strcpy(gplotcondition,"(");
                   7694:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7695:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7696:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7697:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7698:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7699:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7700:              kl++;
                   7701:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7702:              kl++;
                   7703:              if(k <cptcoveff && cptcoveff>1)
                   7704:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7705:            }
                   7706:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7707:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7708:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7709:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7710:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7711:            if(i==nlstate+1){
1.270     brouard  7712:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7713:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7714:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7715:              fprintf(ficgp," u %d:(",iagec); 
                   7716:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7717:                      iyearc, iagec, offyear,                           \
                   7718:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7719: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7720:            }else{
                   7721:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7722:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7723:            }
                   7724:          } /* end if covariate */
                   7725:        } /* nlstate */
1.264     brouard  7726:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7727:       } /* end cpt state*/
                   7728:     } /* end covariate */
                   7729:   } /* End if prevfcast */
1.227     brouard  7730:   
1.268     brouard  7731:   if(backcast==1){
                   7732:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7733:     
                   7734:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7735:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7736:       if(m != 1 && TKresult[nres]!= k1)
                   7737:        continue;
                   7738:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7739:        strcpy(gplotlabel,"(");      
                   7740:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7741:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7742:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7743:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7744:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7745:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7746:          vlv= nbcode[Tvaraff[k]][lv];
                   7747:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7748:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7749:        }
                   7750:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7751:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7752:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7753:        }       
                   7754:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7755:        fprintf(ficgp,"\n#\n");
                   7756:        if(invalidvarcomb[k1]){
                   7757:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7758:          continue;
                   7759:        }
                   7760:        
                   7761:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7762:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7763:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7764:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7765: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7766: 
                   7767:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7768:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7769:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7770:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7771:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7772:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7773:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7774:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7775:          if(i==istart){
                   7776:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7777:          }else{
                   7778:            fprintf(ficgp,",\\\n '' ");
                   7779:          }
                   7780:          if(cptcoveff ==0){ /* No covariate */
                   7781:            ioffset=2; /* Age is in 2 */
                   7782:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7783:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7784:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7785:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7786:            fprintf(ficgp," u %d:(", ioffset); 
                   7787:            if(i==nlstate+1){
1.270     brouard  7788:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7789:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7790:              fprintf(ficgp,",\\\n '' ");
                   7791:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7792:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7793:                     offbyear,                          \
                   7794:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7795:            }else
                   7796:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7797:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7798:          }else{ /* more than 2 covariates */
1.270     brouard  7799:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7800:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7801:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7802:            iyearc=ioffset-1;
                   7803:            iagec=ioffset;
1.268     brouard  7804:            fprintf(ficgp," u %d:(",ioffset); 
                   7805:            kl=0;
                   7806:            strcpy(gplotcondition,"(");
                   7807:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7808:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7809:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7810:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7811:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7812:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7813:              kl++;
                   7814:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7815:              kl++;
                   7816:              if(k <cptcoveff && cptcoveff>1)
                   7817:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7818:            }
                   7819:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7820:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7821:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7822:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7823:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7824:            if(i==nlstate+1){
1.270     brouard  7825:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7826:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7827:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7828:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7829:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7830:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7831:                      iyearc,iagec,offbyear,                            \
                   7832:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7833: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7834:            }else{
                   7835:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7836:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7837:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7838:            }
                   7839:          } /* end if covariate */
                   7840:        } /* nlstate */
                   7841:        fprintf(ficgp,"\nset out; unset label;\n");
                   7842:       } /* end cpt state*/
                   7843:     } /* end covariate */
                   7844:   } /* End if backcast */
                   7845:   
1.227     brouard  7846:   
1.238     brouard  7847:   /* 9eme writing MLE parameters */
                   7848:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7849:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7850:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7851:     for(k=1; k <=(nlstate+ndeath); k++){
                   7852:       if (k != i) {
1.227     brouard  7853:        fprintf(ficgp,"#   current state %d\n",k);
                   7854:        for(j=1; j <=ncovmodel; j++){
                   7855:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7856:          jk++; 
                   7857:        }
                   7858:        fprintf(ficgp,"\n");
1.126     brouard  7859:       }
                   7860:     }
1.223     brouard  7861:   }
1.187     brouard  7862:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7863:   
1.145     brouard  7864:   /*goto avoid;*/
1.238     brouard  7865:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7866:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7867:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7868:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7869:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7870:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7871:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7872:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7873:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7874:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7875:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7876:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7877:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7878:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7879:   fprintf(ficgp,"#\n");
1.223     brouard  7880:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7881:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7882:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7883:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7884:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7885:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7886:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7887:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7888:        continue;
1.264     brouard  7889:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7890:       strcpy(gplotlabel,"(");
1.276     brouard  7891:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  7892:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7893:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7894:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7895:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7896:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7897:        vlv= nbcode[Tvaraff[k]][lv];
                   7898:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7899:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7900:       }
1.237     brouard  7901:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7902:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7903:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7904:       }        
1.264     brouard  7905:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7906:       fprintf(ficgp,"\n#\n");
1.264     brouard  7907:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  7908:       fprintf(ficgp,"\nset key outside ");
                   7909:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   7910:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7911:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7912:       if (ng==1){
                   7913:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7914:        fprintf(ficgp,"\nunset log y");
                   7915:       }else if (ng==2){
                   7916:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7917:        fprintf(ficgp,"\nset log y");
                   7918:       }else if (ng==3){
                   7919:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7920:        fprintf(ficgp,"\nset log y");
                   7921:       }else
                   7922:        fprintf(ficgp,"\nunset title ");
                   7923:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7924:       i=1;
                   7925:       for(k2=1; k2<=nlstate; k2++) {
                   7926:        k3=i;
                   7927:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7928:          if (k != k2){
                   7929:            switch( ng) {
                   7930:            case 1:
                   7931:              if(nagesqr==0)
                   7932:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7933:              else /* nagesqr =1 */
                   7934:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7935:              break;
                   7936:            case 2: /* ng=2 */
                   7937:              if(nagesqr==0)
                   7938:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7939:              else /* nagesqr =1 */
                   7940:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7941:              break;
                   7942:            case 3:
                   7943:              if(nagesqr==0)
                   7944:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7945:              else /* nagesqr =1 */
                   7946:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7947:              break;
                   7948:            }
                   7949:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7950:            ijp=1; /* product no age */
                   7951:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7952:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7953:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7954:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7955:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7956:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7957:                    if(DummyV[j]==0){
                   7958:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7959:                    }else{ /* quantitative */
                   7960:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7961:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7962:                    }
                   7963:                    ij++;
1.237     brouard  7964:                  }
1.268     brouard  7965:                } 
                   7966:              }else if(cptcovprod >0){
                   7967:                if(j==Tprod[ijp]) { /* */ 
                   7968:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7969:                  if(ijp <=cptcovprod) { /* Product */
                   7970:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7971:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7972:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7973:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7974:                      }else{ /* Vn is dummy and Vm is quanti */
                   7975:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7976:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7977:                      }
                   7978:                    }else{ /* Vn*Vm Vn is quanti */
                   7979:                      if(DummyV[Tvard[ijp][2]]==0){
                   7980:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7981:                      }else{ /* Both quanti */
                   7982:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7983:                      }
1.237     brouard  7984:                    }
1.268     brouard  7985:                    ijp++;
1.237     brouard  7986:                  }
1.268     brouard  7987:                } /* end Tprod */
1.237     brouard  7988:              } else{  /* simple covariate */
1.264     brouard  7989:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7990:                if(Dummy[j]==0){
                   7991:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   7992:                }else{ /* quantitative */
                   7993:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  7994:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  7995:                }
1.237     brouard  7996:              } /* end simple */
                   7997:            } /* end j */
1.223     brouard  7998:          }else{
                   7999:            i=i-ncovmodel;
                   8000:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8001:              fprintf(ficgp," (1.");
                   8002:          }
1.227     brouard  8003:          
1.223     brouard  8004:          if(ng != 1){
                   8005:            fprintf(ficgp,")/(1");
1.227     brouard  8006:            
1.264     brouard  8007:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8008:              if(nagesqr==0)
1.264     brouard  8009:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8010:              else /* nagesqr =1 */
1.264     brouard  8011:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8012:               
1.223     brouard  8013:              ij=1;
                   8014:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8015:                 if(cptcovage >0){ 
                   8016:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8017:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8018:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8019:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8020:                       ij++;
                   8021:                     }
                   8022:                   }
                   8023:                 }else
                   8024:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8025:              }
                   8026:              fprintf(ficgp,")");
                   8027:            }
                   8028:            fprintf(ficgp,")");
                   8029:            if(ng ==2)
1.276     brouard  8030:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8031:            else /* ng= 3 */
1.276     brouard  8032:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8033:          }else{ /* end ng <> 1 */
                   8034:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8035:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8036:          }
                   8037:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8038:            fprintf(ficgp,",");
                   8039:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8040:            fprintf(ficgp,",");
                   8041:          i=i+ncovmodel;
                   8042:        } /* end k */
                   8043:       } /* end k2 */
1.276     brouard  8044:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8045:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8046:     } /* end k1 */
1.223     brouard  8047:   } /* end ng */
                   8048:   /* avoid: */
                   8049:   fflush(ficgp); 
1.126     brouard  8050: }  /* end gnuplot */
                   8051: 
                   8052: 
                   8053: /*************** Moving average **************/
1.219     brouard  8054: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8055:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8056:    
1.222     brouard  8057:    int i, cpt, cptcod;
                   8058:    int modcovmax =1;
                   8059:    int mobilavrange, mob;
                   8060:    int iage=0;
1.288     brouard  8061:    int firstA1=0, firstA2=0;
1.222     brouard  8062: 
1.266     brouard  8063:    double sum=0., sumr=0.;
1.222     brouard  8064:    double age;
1.266     brouard  8065:    double *sumnewp, *sumnewm, *sumnewmr;
                   8066:    double *agemingood, *agemaxgood; 
                   8067:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8068:   
                   8069:   
1.278     brouard  8070:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8071:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8072: 
                   8073:    sumnewp = vector(1,ncovcombmax);
                   8074:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8075:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8076:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8077:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8078:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8079:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8080: 
                   8081:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8082:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8083:      sumnewp[cptcod]=0.;
1.266     brouard  8084:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8085:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8086:    }
                   8087:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8088:   
1.266     brouard  8089:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8090:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8091:      else mobilavrange=mobilav;
                   8092:      for (age=bage; age<=fage; age++)
                   8093:        for (i=1; i<=nlstate;i++)
                   8094:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8095:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8096:      /* We keep the original values on the extreme ages bage, fage and for 
                   8097:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8098:        we use a 5 terms etc. until the borders are no more concerned. 
                   8099:      */ 
                   8100:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8101:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8102:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8103:           sumnewm[cptcod]=0.;
                   8104:           for (i=1; i<=nlstate;i++){
1.222     brouard  8105:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8106:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8107:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8108:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8109:             }
                   8110:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8111:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8112:           } /* end i */
                   8113:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8114:         } /* end cptcod */
1.222     brouard  8115:        }/* end age */
                   8116:      }/* end mob */
1.266     brouard  8117:    }else{
                   8118:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8119:      return -1;
1.266     brouard  8120:    }
                   8121: 
                   8122:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8123:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8124:      if(invalidvarcomb[cptcod]){
                   8125:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8126:        continue;
                   8127:      }
1.219     brouard  8128: 
1.266     brouard  8129:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8130:        sumnewm[cptcod]=0.;
                   8131:        sumnewmr[cptcod]=0.;
                   8132:        for (i=1; i<=nlstate;i++){
                   8133:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8134:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8135:        }
                   8136:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8137:         agemingoodr[cptcod]=age;
                   8138:        }
                   8139:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8140:           agemingood[cptcod]=age;
                   8141:        }
                   8142:      } /* age */
                   8143:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8144:        sumnewm[cptcod]=0.;
1.266     brouard  8145:        sumnewmr[cptcod]=0.;
1.222     brouard  8146:        for (i=1; i<=nlstate;i++){
                   8147:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8148:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8149:        }
                   8150:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8151:         agemaxgoodr[cptcod]=age;
1.222     brouard  8152:        }
                   8153:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8154:         agemaxgood[cptcod]=age;
                   8155:        }
                   8156:      } /* age */
                   8157:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8158:      /* but they will change */
1.288     brouard  8159:      firstA1=0;firstA2=0;
1.266     brouard  8160:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8161:        sumnewm[cptcod]=0.;
                   8162:        sumnewmr[cptcod]=0.;
                   8163:        for (i=1; i<=nlstate;i++){
                   8164:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8165:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8166:        }
                   8167:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8168:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8169:           agemaxgoodr[cptcod]=age;  /* age min */
                   8170:           for (i=1; i<=nlstate;i++)
                   8171:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8172:         }else{ /* bad we change the value with the values of good ages */
                   8173:           for (i=1; i<=nlstate;i++){
                   8174:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8175:           } /* i */
                   8176:         } /* end bad */
                   8177:        }else{
                   8178:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8179:           agemaxgood[cptcod]=age;
                   8180:         }else{ /* bad we change the value with the values of good ages */
                   8181:           for (i=1; i<=nlstate;i++){
                   8182:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8183:           } /* i */
                   8184:         } /* end bad */
                   8185:        }/* end else */
                   8186:        sum=0.;sumr=0.;
                   8187:        for (i=1; i<=nlstate;i++){
                   8188:         sum+=mobaverage[(int)age][i][cptcod];
                   8189:         sumr+=probs[(int)age][i][cptcod];
                   8190:        }
                   8191:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8192:         if(!firstA1){
                   8193:           firstA1=1;
                   8194:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8195:         }
                   8196:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8197:        } /* end bad */
                   8198:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8199:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8200:         if(!firstA2){
                   8201:           firstA2=1;
                   8202:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8203:         }
                   8204:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8205:        } /* end bad */
                   8206:      }/* age */
1.266     brouard  8207: 
                   8208:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8209:        sumnewm[cptcod]=0.;
1.266     brouard  8210:        sumnewmr[cptcod]=0.;
1.222     brouard  8211:        for (i=1; i<=nlstate;i++){
                   8212:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8213:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8214:        } 
                   8215:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8216:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8217:           agemingoodr[cptcod]=age;
                   8218:           for (i=1; i<=nlstate;i++)
                   8219:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8220:         }else{ /* bad we change the value with the values of good ages */
                   8221:           for (i=1; i<=nlstate;i++){
                   8222:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8223:           } /* i */
                   8224:         } /* end bad */
                   8225:        }else{
                   8226:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8227:           agemingood[cptcod]=age;
                   8228:         }else{ /* bad */
                   8229:           for (i=1; i<=nlstate;i++){
                   8230:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8231:           } /* i */
                   8232:         } /* end bad */
                   8233:        }/* end else */
                   8234:        sum=0.;sumr=0.;
                   8235:        for (i=1; i<=nlstate;i++){
                   8236:         sum+=mobaverage[(int)age][i][cptcod];
                   8237:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8238:        }
1.266     brouard  8239:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8240:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8241:        } /* end bad */
                   8242:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8243:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8244:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8245:        } /* end bad */
                   8246:      }/* age */
1.266     brouard  8247: 
1.222     brouard  8248:                
                   8249:      for (age=bage; age<=fage; age++){
1.235     brouard  8250:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8251:        sumnewp[cptcod]=0.;
                   8252:        sumnewm[cptcod]=0.;
                   8253:        for (i=1; i<=nlstate;i++){
                   8254:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8255:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8256:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8257:        }
                   8258:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8259:      }
                   8260:      /* printf("\n"); */
                   8261:      /* } */
1.266     brouard  8262: 
1.222     brouard  8263:      /* brutal averaging */
1.266     brouard  8264:      /* for (i=1; i<=nlstate;i++){ */
                   8265:      /*   for (age=1; age<=bage; age++){ */
                   8266:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8267:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8268:      /*   }     */
                   8269:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8270:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8271:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8272:      /*   } */
                   8273:      /* } /\* end i status *\/ */
                   8274:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8275:      /*   for (age=1; age<=AGESUP; age++){ */
                   8276:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8277:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8278:      /*   } */
                   8279:      /* } */
1.222     brouard  8280:    }/* end cptcod */
1.266     brouard  8281:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8282:    free_vector(agemaxgood,1, ncovcombmax);
                   8283:    free_vector(agemingood,1, ncovcombmax);
                   8284:    free_vector(agemingoodr,1, ncovcombmax);
                   8285:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8286:    free_vector(sumnewm,1, ncovcombmax);
                   8287:    free_vector(sumnewp,1, ncovcombmax);
                   8288:    return 0;
                   8289:  }/* End movingaverage */
1.218     brouard  8290:  
1.126     brouard  8291: 
                   8292: /************** Forecasting ******************/
1.269     brouard  8293:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8294:   /* proj1, year, month, day of starting projection 
                   8295:      agemin, agemax range of age
                   8296:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8297:      anproj2 year of en of projection (same day and month as proj1).
                   8298:   */
1.267     brouard  8299:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8300:   double agec; /* generic age */
                   8301:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8302:   double *popeffectif,*popcount;
                   8303:   double ***p3mat;
1.218     brouard  8304:   /* double ***mobaverage; */
1.126     brouard  8305:   char fileresf[FILENAMELENGTH];
                   8306: 
                   8307:   agelim=AGESUP;
1.211     brouard  8308:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8309:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8310:      We still use firstpass and lastpass as another selection.
                   8311:   */
1.214     brouard  8312:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8313:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8314:  
1.201     brouard  8315:   strcpy(fileresf,"F_"); 
                   8316:   strcat(fileresf,fileresu);
1.126     brouard  8317:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8318:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8319:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8320:   }
1.235     brouard  8321:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8322:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8323: 
1.225     brouard  8324:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8325: 
                   8326: 
                   8327:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8328:   if (stepm<=12) stepsize=1;
                   8329:   if(estepm < stepm){
                   8330:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8331:   }
1.270     brouard  8332:   else{
                   8333:     hstepm=estepm;   
                   8334:   }
                   8335:   if(estepm > stepm){ /* Yes every two year */
                   8336:     stepsize=2;
                   8337:   }
1.126     brouard  8338: 
                   8339:   hstepm=hstepm/stepm; 
                   8340:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8341:                                fractional in yp1 */
                   8342:   anprojmean=yp;
                   8343:   yp2=modf((yp1*12),&yp);
                   8344:   mprojmean=yp;
                   8345:   yp1=modf((yp2*30.5),&yp);
                   8346:   jprojmean=yp;
                   8347:   if(jprojmean==0) jprojmean=1;
                   8348:   if(mprojmean==0) jprojmean=1;
                   8349: 
1.227     brouard  8350:   i1=pow(2,cptcoveff);
1.126     brouard  8351:   if (cptcovn < 1){i1=1;}
                   8352:   
                   8353:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8354:   
                   8355:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8356:   
1.126     brouard  8357: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8358:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8359:   for(k=1; k<=i1;k++){
1.253     brouard  8360:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8361:       continue;
1.227     brouard  8362:     if(invalidvarcomb[k]){
                   8363:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8364:       continue;
                   8365:     }
                   8366:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8367:     for(j=1;j<=cptcoveff;j++) {
                   8368:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8369:     }
1.235     brouard  8370:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8371:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8372:     }
1.227     brouard  8373:     fprintf(ficresf," yearproj age");
                   8374:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8375:       for(i=1; i<=nlstate;i++)               
                   8376:        fprintf(ficresf," p%d%d",i,j);
                   8377:       fprintf(ficresf," wp.%d",j);
                   8378:     }
                   8379:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8380:       fprintf(ficresf,"\n");
                   8381:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8382:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8383:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8384:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8385:        nhstepm = nhstepm/hstepm; 
                   8386:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8387:        oldm=oldms;savm=savms;
1.268     brouard  8388:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8389:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8390:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8391:        for (h=0; h<=nhstepm; h++){
                   8392:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8393:            break;
                   8394:          }
                   8395:        }
                   8396:        fprintf(ficresf,"\n");
                   8397:        for(j=1;j<=cptcoveff;j++) 
                   8398:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8399:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8400:        
                   8401:        for(j=1; j<=nlstate+ndeath;j++) {
                   8402:          ppij=0.;
                   8403:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8404:            if (mobilav>=1)
                   8405:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8406:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8407:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8408:            }
1.268     brouard  8409:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8410:          } /* end i */
                   8411:          fprintf(ficresf," %.3f", ppij);
                   8412:        }/* end j */
1.227     brouard  8413:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8414:       } /* end agec */
1.266     brouard  8415:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8416:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8417:     } /* end yearp */
                   8418:   } /* end  k */
1.219     brouard  8419:        
1.126     brouard  8420:   fclose(ficresf);
1.215     brouard  8421:   printf("End of Computing forecasting \n");
                   8422:   fprintf(ficlog,"End of Computing forecasting\n");
                   8423: 
1.126     brouard  8424: }
                   8425: 
1.269     brouard  8426: /************** Back Forecasting ******************/
                   8427:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8428:   /* back1, year, month, day of starting backection
                   8429:      agemin, agemax range of age
                   8430:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8431:      anback2 year of end of backprojection (same day and month as back1).
                   8432:      prevacurrent and prev are prevalences.
1.267     brouard  8433:   */
                   8434:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8435:   double agec; /* generic age */
1.268     brouard  8436:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8437:   double *popeffectif,*popcount;
                   8438:   double ***p3mat;
                   8439:   /* double ***mobaverage; */
                   8440:   char fileresfb[FILENAMELENGTH];
                   8441:  
1.268     brouard  8442:   agelim=AGEINF;
1.267     brouard  8443:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8444:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8445:      We still use firstpass and lastpass as another selection.
                   8446:   */
                   8447:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8448:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8449: 
                   8450:   /*Do we need to compute prevalence again?*/
                   8451: 
                   8452:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8453:   
                   8454:   strcpy(fileresfb,"FB_");
                   8455:   strcat(fileresfb,fileresu);
                   8456:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8457:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8458:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8459:   }
                   8460:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8461:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8462:   
                   8463:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8464:   
                   8465:    
                   8466:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8467:   if (stepm<=12) stepsize=1;
                   8468:   if(estepm < stepm){
                   8469:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8470:   }
1.270     brouard  8471:   else{
                   8472:     hstepm=estepm;   
                   8473:   }
                   8474:   if(estepm >= stepm){ /* Yes every two year */
                   8475:     stepsize=2;
                   8476:   }
1.267     brouard  8477:   
                   8478:   hstepm=hstepm/stepm;
                   8479:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8480:                                fractional in yp1 */
                   8481:   anprojmean=yp;
                   8482:   yp2=modf((yp1*12),&yp);
                   8483:   mprojmean=yp;
                   8484:   yp1=modf((yp2*30.5),&yp);
                   8485:   jprojmean=yp;
                   8486:   if(jprojmean==0) jprojmean=1;
                   8487:   if(mprojmean==0) jprojmean=1;
                   8488:   
                   8489:   i1=pow(2,cptcoveff);
                   8490:   if (cptcovn < 1){i1=1;}
                   8491:   
                   8492:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8493:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8494:   
                   8495:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8496:   
                   8497:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8498:   for(k=1; k<=i1;k++){
                   8499:     if(i1 != 1 && TKresult[nres]!= k)
                   8500:       continue;
                   8501:     if(invalidvarcomb[k]){
                   8502:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8503:       continue;
                   8504:     }
1.268     brouard  8505:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8506:     for(j=1;j<=cptcoveff;j++) {
                   8507:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8508:     }
                   8509:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8510:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8511:     }
                   8512:     fprintf(ficresfb," yearbproj age");
                   8513:     for(j=1; j<=nlstate+ndeath;j++){
                   8514:       for(i=1; i<=nlstate;i++)
1.268     brouard  8515:        fprintf(ficresfb," b%d%d",i,j);
                   8516:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8517:     }
                   8518:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8519:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8520:       fprintf(ficresfb,"\n");
                   8521:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.273     brouard  8522:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8523:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8524:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8525:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8526:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8527:        nhstepm = nhstepm/hstepm;
                   8528:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8529:        oldm=oldms;savm=savms;
1.268     brouard  8530:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8531:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8532:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8533:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8534:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8535:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8536:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8537:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8538:            break;
                   8539:          }
                   8540:        }
                   8541:        fprintf(ficresfb,"\n");
                   8542:        for(j=1;j<=cptcoveff;j++)
                   8543:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8544:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8545:        for(i=1; i<=nlstate+ndeath;i++) {
                   8546:          ppij=0.;ppi=0.;
                   8547:          for(j=1; j<=nlstate;j++) {
                   8548:            /* if (mobilav==1) */
1.269     brouard  8549:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8550:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8551:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8552:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8553:              /* else { */
                   8554:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8555:              /* } */
1.268     brouard  8556:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8557:          } /* end j */
                   8558:          if(ppi <0.99){
                   8559:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8560:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8561:          }
                   8562:          fprintf(ficresfb," %.3f", ppij);
                   8563:        }/* end j */
1.267     brouard  8564:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8565:       } /* end agec */
                   8566:     } /* end yearp */
                   8567:   } /* end k */
1.217     brouard  8568:   
1.267     brouard  8569:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8570:   
1.267     brouard  8571:   fclose(ficresfb);
                   8572:   printf("End of Computing Back forecasting \n");
                   8573:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8574:        
1.267     brouard  8575: }
1.217     brouard  8576: 
1.269     brouard  8577: /* Variance of prevalence limit: varprlim */
                   8578:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8579:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8580:  
                   8581:    char fileresvpl[FILENAMELENGTH];  
                   8582:    FILE *ficresvpl;
                   8583:    double **oldm, **savm;
                   8584:    double **varpl; /* Variances of prevalence limits by age */   
                   8585:    int i1, k, nres, j ;
                   8586:    
                   8587:     strcpy(fileresvpl,"VPL_");
                   8588:     strcat(fileresvpl,fileresu);
                   8589:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8590:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8591:       exit(0);
                   8592:     }
1.288     brouard  8593:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8594:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8595:     
                   8596:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8597:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8598:     
                   8599:     i1=pow(2,cptcoveff);
                   8600:     if (cptcovn < 1){i1=1;}
                   8601: 
                   8602:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8603:     for(k=1; k<=i1;k++){
                   8604:       if(i1 != 1 && TKresult[nres]!= k)
                   8605:        continue;
                   8606:       fprintf(ficresvpl,"\n#****** ");
                   8607:       printf("\n#****** ");
                   8608:       fprintf(ficlog,"\n#****** ");
                   8609:       for(j=1;j<=cptcoveff;j++) {
                   8610:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8611:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8612:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8613:       }
                   8614:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8615:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8616:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8617:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8618:       }        
                   8619:       fprintf(ficresvpl,"******\n");
                   8620:       printf("******\n");
                   8621:       fprintf(ficlog,"******\n");
                   8622:       
                   8623:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8624:       oldm=oldms;savm=savms;
                   8625:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8626:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8627:       /*}*/
                   8628:     }
                   8629:     
                   8630:     fclose(ficresvpl);
1.288     brouard  8631:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   8632:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  8633: 
                   8634:  }
                   8635: /* Variance of back prevalence: varbprlim */
                   8636:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8637:       /*------- Variance of back (stable) prevalence------*/
                   8638: 
                   8639:    char fileresvbl[FILENAMELENGTH];  
                   8640:    FILE  *ficresvbl;
                   8641: 
                   8642:    double **oldm, **savm;
                   8643:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8644:    int i1, k, nres, j ;
                   8645: 
                   8646:    strcpy(fileresvbl,"VBL_");
                   8647:    strcat(fileresvbl,fileresu);
                   8648:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8649:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8650:      exit(0);
                   8651:    }
                   8652:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8653:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8654:    
                   8655:    
                   8656:    i1=pow(2,cptcoveff);
                   8657:    if (cptcovn < 1){i1=1;}
                   8658:    
                   8659:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8660:      for(k=1; k<=i1;k++){
                   8661:        if(i1 != 1 && TKresult[nres]!= k)
                   8662:         continue;
                   8663:        fprintf(ficresvbl,"\n#****** ");
                   8664:        printf("\n#****** ");
                   8665:        fprintf(ficlog,"\n#****** ");
                   8666:        for(j=1;j<=cptcoveff;j++) {
                   8667:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8668:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8669:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8670:        }
                   8671:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8672:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8673:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8674:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8675:        }
                   8676:        fprintf(ficresvbl,"******\n");
                   8677:        printf("******\n");
                   8678:        fprintf(ficlog,"******\n");
                   8679:        
                   8680:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8681:        oldm=oldms;savm=savms;
                   8682:        
                   8683:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8684:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8685:        /*}*/
                   8686:      }
                   8687:    
                   8688:    fclose(ficresvbl);
                   8689:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8690:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8691: 
                   8692:  } /* End of varbprlim */
                   8693: 
1.126     brouard  8694: /************** Forecasting *****not tested NB*************/
1.227     brouard  8695: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8696:   
1.227     brouard  8697: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8698: /*   int *popage; */
                   8699: /*   double calagedatem, agelim, kk1, kk2; */
                   8700: /*   double *popeffectif,*popcount; */
                   8701: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8702: /*   /\* double ***mobaverage; *\/ */
                   8703: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8704: 
1.227     brouard  8705: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8706: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8707: /*   agelim=AGESUP; */
                   8708: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8709:   
1.227     brouard  8710: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8711:   
                   8712:   
1.227     brouard  8713: /*   strcpy(filerespop,"POP_");  */
                   8714: /*   strcat(filerespop,fileresu); */
                   8715: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8716: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8717: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8718: /*   } */
                   8719: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8720: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8721: 
1.227     brouard  8722: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8723: 
1.227     brouard  8724: /*   /\* if (mobilav!=0) { *\/ */
                   8725: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8726: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8727: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8728: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8729: /*   /\*   } *\/ */
                   8730: /*   /\* } *\/ */
1.126     brouard  8731: 
1.227     brouard  8732: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8733: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8734:   
1.227     brouard  8735: /*   agelim=AGESUP; */
1.126     brouard  8736:   
1.227     brouard  8737: /*   hstepm=1; */
                   8738: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8739:        
1.227     brouard  8740: /*   if (popforecast==1) { */
                   8741: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8742: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8743: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8744: /*     }  */
                   8745: /*     popage=ivector(0,AGESUP); */
                   8746: /*     popeffectif=vector(0,AGESUP); */
                   8747: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8748:     
1.227     brouard  8749: /*     i=1;    */
                   8750: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8751:     
1.227     brouard  8752: /*     imx=i; */
                   8753: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8754: /*   } */
1.218     brouard  8755:   
1.227     brouard  8756: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8757: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8758: /*       k=k+1; */
                   8759: /*       fprintf(ficrespop,"\n#******"); */
                   8760: /*       for(j=1;j<=cptcoveff;j++) { */
                   8761: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8762: /*       } */
                   8763: /*       fprintf(ficrespop,"******\n"); */
                   8764: /*       fprintf(ficrespop,"# Age"); */
                   8765: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8766: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8767:       
1.227     brouard  8768: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8769: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8770:        
1.227     brouard  8771: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8772: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8773: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8774:          
1.227     brouard  8775: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8776: /*       oldm=oldms;savm=savms; */
                   8777: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8778:          
1.227     brouard  8779: /*       for (h=0; h<=nhstepm; h++){ */
                   8780: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8781: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8782: /*         }  */
                   8783: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8784: /*           kk1=0.;kk2=0; */
                   8785: /*           for(i=1; i<=nlstate;i++) {               */
                   8786: /*             if (mobilav==1)  */
                   8787: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8788: /*             else { */
                   8789: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8790: /*             } */
                   8791: /*           } */
                   8792: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8793: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8794: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8795: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8796: /*           } */
                   8797: /*         } */
                   8798: /*         for(i=1; i<=nlstate;i++){ */
                   8799: /*           kk1=0.; */
                   8800: /*           for(j=1; j<=nlstate;j++){ */
                   8801: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8802: /*           } */
                   8803: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8804: /*         } */
1.218     brouard  8805:            
1.227     brouard  8806: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8807: /*           for(j=1; j<=nlstate;j++)  */
                   8808: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8809: /*       } */
                   8810: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8811: /*     } */
                   8812: /*       } */
1.218     brouard  8813:       
1.227     brouard  8814: /*       /\******\/ */
1.218     brouard  8815:       
1.227     brouard  8816: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8817: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8818: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8819: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8820: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8821:          
1.227     brouard  8822: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8823: /*       oldm=oldms;savm=savms; */
                   8824: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8825: /*       for (h=0; h<=nhstepm; h++){ */
                   8826: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8827: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8828: /*         }  */
                   8829: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8830: /*           kk1=0.;kk2=0; */
                   8831: /*           for(i=1; i<=nlstate;i++) {               */
                   8832: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8833: /*           } */
                   8834: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8835: /*         } */
                   8836: /*       } */
                   8837: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8838: /*     } */
                   8839: /*       } */
                   8840: /*     }  */
                   8841: /*   } */
1.218     brouard  8842:   
1.227     brouard  8843: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8844:   
1.227     brouard  8845: /*   if (popforecast==1) { */
                   8846: /*     free_ivector(popage,0,AGESUP); */
                   8847: /*     free_vector(popeffectif,0,AGESUP); */
                   8848: /*     free_vector(popcount,0,AGESUP); */
                   8849: /*   } */
                   8850: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8851: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8852: /*   fclose(ficrespop); */
                   8853: /* } /\* End of popforecast *\/ */
1.218     brouard  8854:  
1.126     brouard  8855: int fileappend(FILE *fichier, char *optionfich)
                   8856: {
                   8857:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8858:     printf("Problem with file: %s\n", optionfich);
                   8859:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8860:     return (0);
                   8861:   }
                   8862:   fflush(fichier);
                   8863:   return (1);
                   8864: }
                   8865: 
                   8866: 
                   8867: /**************** function prwizard **********************/
                   8868: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8869: {
                   8870: 
                   8871:   /* Wizard to print covariance matrix template */
                   8872: 
1.164     brouard  8873:   char ca[32], cb[32];
                   8874:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8875:   int numlinepar;
                   8876: 
                   8877:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8878:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8879:   for(i=1; i <=nlstate; i++){
                   8880:     jj=0;
                   8881:     for(j=1; j <=nlstate+ndeath; j++){
                   8882:       if(j==i) continue;
                   8883:       jj++;
                   8884:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8885:       printf("%1d%1d",i,j);
                   8886:       fprintf(ficparo,"%1d%1d",i,j);
                   8887:       for(k=1; k<=ncovmodel;k++){
                   8888:        /*        printf(" %lf",param[i][j][k]); */
                   8889:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8890:        printf(" 0.");
                   8891:        fprintf(ficparo," 0.");
                   8892:       }
                   8893:       printf("\n");
                   8894:       fprintf(ficparo,"\n");
                   8895:     }
                   8896:   }
                   8897:   printf("# Scales (for hessian or gradient estimation)\n");
                   8898:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8899:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8900:   for(i=1; i <=nlstate; i++){
                   8901:     jj=0;
                   8902:     for(j=1; j <=nlstate+ndeath; j++){
                   8903:       if(j==i) continue;
                   8904:       jj++;
                   8905:       fprintf(ficparo,"%1d%1d",i,j);
                   8906:       printf("%1d%1d",i,j);
                   8907:       fflush(stdout);
                   8908:       for(k=1; k<=ncovmodel;k++){
                   8909:        /*      printf(" %le",delti3[i][j][k]); */
                   8910:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8911:        printf(" 0.");
                   8912:        fprintf(ficparo," 0.");
                   8913:       }
                   8914:       numlinepar++;
                   8915:       printf("\n");
                   8916:       fprintf(ficparo,"\n");
                   8917:     }
                   8918:   }
                   8919:   printf("# Covariance matrix\n");
                   8920: /* # 121 Var(a12)\n\ */
                   8921: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8922: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8923: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8924: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8925: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8926: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8927: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8928:   fflush(stdout);
                   8929:   fprintf(ficparo,"# Covariance matrix\n");
                   8930:   /* # 121 Var(a12)\n\ */
                   8931:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8932:   /* #   ...\n\ */
                   8933:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8934:   
                   8935:   for(itimes=1;itimes<=2;itimes++){
                   8936:     jj=0;
                   8937:     for(i=1; i <=nlstate; i++){
                   8938:       for(j=1; j <=nlstate+ndeath; j++){
                   8939:        if(j==i) continue;
                   8940:        for(k=1; k<=ncovmodel;k++){
                   8941:          jj++;
                   8942:          ca[0]= k+'a'-1;ca[1]='\0';
                   8943:          if(itimes==1){
                   8944:            printf("#%1d%1d%d",i,j,k);
                   8945:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8946:          }else{
                   8947:            printf("%1d%1d%d",i,j,k);
                   8948:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8949:            /*  printf(" %.5le",matcov[i][j]); */
                   8950:          }
                   8951:          ll=0;
                   8952:          for(li=1;li <=nlstate; li++){
                   8953:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8954:              if(lj==li) continue;
                   8955:              for(lk=1;lk<=ncovmodel;lk++){
                   8956:                ll++;
                   8957:                if(ll<=jj){
                   8958:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8959:                  if(ll<jj){
                   8960:                    if(itimes==1){
                   8961:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8962:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8963:                    }else{
                   8964:                      printf(" 0.");
                   8965:                      fprintf(ficparo," 0.");
                   8966:                    }
                   8967:                  }else{
                   8968:                    if(itimes==1){
                   8969:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8970:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8971:                    }else{
                   8972:                      printf(" 0.");
                   8973:                      fprintf(ficparo," 0.");
                   8974:                    }
                   8975:                  }
                   8976:                }
                   8977:              } /* end lk */
                   8978:            } /* end lj */
                   8979:          } /* end li */
                   8980:          printf("\n");
                   8981:          fprintf(ficparo,"\n");
                   8982:          numlinepar++;
                   8983:        } /* end k*/
                   8984:       } /*end j */
                   8985:     } /* end i */
                   8986:   } /* end itimes */
                   8987: 
                   8988: } /* end of prwizard */
                   8989: /******************* Gompertz Likelihood ******************************/
                   8990: double gompertz(double x[])
                   8991: { 
                   8992:   double A,B,L=0.0,sump=0.,num=0.;
                   8993:   int i,n=0; /* n is the size of the sample */
                   8994: 
1.220     brouard  8995:   for (i=1;i<=imx ; i++) {
1.126     brouard  8996:     sump=sump+weight[i];
                   8997:     /*    sump=sump+1;*/
                   8998:     num=num+1;
                   8999:   }
                   9000:  
                   9001:  
                   9002:   /* for (i=0; i<=imx; i++) 
                   9003:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9004: 
                   9005:   for (i=1;i<=imx ; i++)
                   9006:     {
                   9007:       if (cens[i] == 1 && wav[i]>1)
                   9008:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9009:       
                   9010:       if (cens[i] == 0 && wav[i]>1)
                   9011:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   9012:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   9013:       
                   9014:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9015:       if (wav[i] > 1 ) { /* ??? */
                   9016:        L=L+A*weight[i];
                   9017:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9018:       }
                   9019:     }
                   9020: 
                   9021:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9022:  
                   9023:   return -2*L*num/sump;
                   9024: }
                   9025: 
1.136     brouard  9026: #ifdef GSL
                   9027: /******************* Gompertz_f Likelihood ******************************/
                   9028: double gompertz_f(const gsl_vector *v, void *params)
                   9029: { 
                   9030:   double A,B,LL=0.0,sump=0.,num=0.;
                   9031:   double *x= (double *) v->data;
                   9032:   int i,n=0; /* n is the size of the sample */
                   9033: 
                   9034:   for (i=0;i<=imx-1 ; i++) {
                   9035:     sump=sump+weight[i];
                   9036:     /*    sump=sump+1;*/
                   9037:     num=num+1;
                   9038:   }
                   9039:  
                   9040:  
                   9041:   /* for (i=0; i<=imx; i++) 
                   9042:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9043:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9044:   for (i=1;i<=imx ; i++)
                   9045:     {
                   9046:       if (cens[i] == 1 && wav[i]>1)
                   9047:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9048:       
                   9049:       if (cens[i] == 0 && wav[i]>1)
                   9050:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9051:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9052:       
                   9053:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9054:       if (wav[i] > 1 ) { /* ??? */
                   9055:        LL=LL+A*weight[i];
                   9056:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9057:       }
                   9058:     }
                   9059: 
                   9060:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9061:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9062:  
                   9063:   return -2*LL*num/sump;
                   9064: }
                   9065: #endif
                   9066: 
1.126     brouard  9067: /******************* Printing html file ***********/
1.201     brouard  9068: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9069:                  int lastpass, int stepm, int weightopt, char model[],\
                   9070:                  int imx,  double p[],double **matcov,double agemortsup){
                   9071:   int i,k;
                   9072: 
                   9073:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9074:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9075:   for (i=1;i<=2;i++) 
                   9076:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9077:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9078:   fprintf(fichtm,"</ul>");
                   9079: 
                   9080: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9081: 
                   9082:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9083: 
                   9084:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9085:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9086: 
                   9087:  
                   9088:   fflush(fichtm);
                   9089: }
                   9090: 
                   9091: /******************* Gnuplot file **************/
1.201     brouard  9092: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9093: 
                   9094:   char dirfileres[132],optfileres[132];
1.164     brouard  9095: 
1.126     brouard  9096:   int ng;
                   9097: 
                   9098: 
                   9099:   /*#ifdef windows */
                   9100:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9101:     /*#endif */
                   9102: 
                   9103: 
                   9104:   strcpy(dirfileres,optionfilefiname);
                   9105:   strcpy(optfileres,"vpl");
1.199     brouard  9106:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9107:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9108:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9109:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9110:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9111: 
                   9112: } 
                   9113: 
1.136     brouard  9114: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9115: {
1.126     brouard  9116: 
1.136     brouard  9117:   /*-------- data file ----------*/
                   9118:   FILE *fic;
                   9119:   char dummy[]="                         ";
1.240     brouard  9120:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9121:   int lstra;
1.136     brouard  9122:   int linei, month, year,iout;
                   9123:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9124:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9125:   char *stratrunc;
1.223     brouard  9126: 
1.240     brouard  9127:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9128:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9129: 
1.240     brouard  9130:   for(v=1; v <=ncovcol;v++){
                   9131:     DummyV[v]=0;
                   9132:     FixedV[v]=0;
                   9133:   }
                   9134:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9135:     DummyV[v]=1;
                   9136:     FixedV[v]=0;
                   9137:   }
                   9138:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9139:     DummyV[v]=0;
                   9140:     FixedV[v]=1;
                   9141:   }
                   9142:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9143:     DummyV[v]=1;
                   9144:     FixedV[v]=1;
                   9145:   }
                   9146:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9147:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9148:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9149:   }
1.126     brouard  9150: 
1.136     brouard  9151:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9152:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9153:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9154:   }
1.126     brouard  9155: 
1.136     brouard  9156:   i=1;
                   9157:   linei=0;
                   9158:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9159:     linei=linei+1;
                   9160:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9161:       if(line[j] == '\t')
                   9162:        line[j] = ' ';
                   9163:     }
                   9164:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9165:       ;
                   9166:     };
                   9167:     line[j+1]=0;  /* Trims blanks at end of line */
                   9168:     if(line[0]=='#'){
                   9169:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9170:       printf("Comment line\n%s\n",line);
                   9171:       continue;
                   9172:     }
                   9173:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9174:     strcpy(line, linetmp);
1.223     brouard  9175:     
                   9176:     /* Loops on waves */
                   9177:     for (j=maxwav;j>=1;j--){
                   9178:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9179:        cutv(stra, strb, line, ' '); 
                   9180:        if(strb[0]=='.') { /* Missing value */
                   9181:          lval=-1;
                   9182:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9183:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9184:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9185:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9186:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9187:            return 1;
                   9188:          }
                   9189:        }else{
                   9190:          errno=0;
                   9191:          /* what_kind_of_number(strb); */
                   9192:          dval=strtod(strb,&endptr); 
                   9193:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9194:          /* if(strb != endptr && *endptr == '\0') */
                   9195:          /*    dval=dlval; */
                   9196:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9197:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9198:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9199:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9200:            return 1;
                   9201:          }
                   9202:          cotqvar[j][iv][i]=dval; 
                   9203:          cotvar[j][ntv+iv][i]=dval; 
                   9204:        }
                   9205:        strcpy(line,stra);
1.223     brouard  9206:       }/* end loop ntqv */
1.225     brouard  9207:       
1.223     brouard  9208:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9209:        cutv(stra, strb, line, ' '); 
                   9210:        if(strb[0]=='.') { /* Missing value */
                   9211:          lval=-1;
                   9212:        }else{
                   9213:          errno=0;
                   9214:          lval=strtol(strb,&endptr,10); 
                   9215:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9216:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9217:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9218:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9219:            return 1;
                   9220:          }
                   9221:        }
                   9222:        if(lval <-1 || lval >1){
                   9223:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9224:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9225:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9226:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9227:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9228:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9229:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9230:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9231:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9232:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9233:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9234:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9235:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9236:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9237:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9238:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9239:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9240:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9241:          return 1;
                   9242:        }
                   9243:        cotvar[j][iv][i]=(double)(lval);
                   9244:        strcpy(line,stra);
1.223     brouard  9245:       }/* end loop ntv */
1.225     brouard  9246:       
1.223     brouard  9247:       /* Statuses  at wave */
1.137     brouard  9248:       cutv(stra, strb, line, ' '); 
1.223     brouard  9249:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9250:        lval=-1;
1.136     brouard  9251:       }else{
1.238     brouard  9252:        errno=0;
                   9253:        lval=strtol(strb,&endptr,10); 
                   9254:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9255:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9256:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9257:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9258:          return 1;
                   9259:        }
1.136     brouard  9260:       }
1.225     brouard  9261:       
1.136     brouard  9262:       s[j][i]=lval;
1.225     brouard  9263:       
1.223     brouard  9264:       /* Date of Interview */
1.136     brouard  9265:       strcpy(line,stra);
                   9266:       cutv(stra, strb,line,' ');
1.169     brouard  9267:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9268:       }
1.169     brouard  9269:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9270:        month=99;
                   9271:        year=9999;
1.136     brouard  9272:       }else{
1.225     brouard  9273:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9274:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9275:        return 1;
1.136     brouard  9276:       }
                   9277:       anint[j][i]= (double) year; 
                   9278:       mint[j][i]= (double)month; 
                   9279:       strcpy(line,stra);
1.223     brouard  9280:     } /* End loop on waves */
1.225     brouard  9281:     
1.223     brouard  9282:     /* Date of death */
1.136     brouard  9283:     cutv(stra, strb,line,' '); 
1.169     brouard  9284:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9285:     }
1.169     brouard  9286:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9287:       month=99;
                   9288:       year=9999;
                   9289:     }else{
1.141     brouard  9290:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9291:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9292:       return 1;
1.136     brouard  9293:     }
                   9294:     andc[i]=(double) year; 
                   9295:     moisdc[i]=(double) month; 
                   9296:     strcpy(line,stra);
                   9297:     
1.223     brouard  9298:     /* Date of birth */
1.136     brouard  9299:     cutv(stra, strb,line,' '); 
1.169     brouard  9300:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9301:     }
1.169     brouard  9302:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9303:       month=99;
                   9304:       year=9999;
                   9305:     }else{
1.141     brouard  9306:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9307:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9308:       return 1;
1.136     brouard  9309:     }
                   9310:     if (year==9999) {
1.141     brouard  9311:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9312:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9313:       return 1;
                   9314:       
1.136     brouard  9315:     }
                   9316:     annais[i]=(double)(year);
                   9317:     moisnais[i]=(double)(month); 
                   9318:     strcpy(line,stra);
1.225     brouard  9319:     
1.223     brouard  9320:     /* Sample weight */
1.136     brouard  9321:     cutv(stra, strb,line,' '); 
                   9322:     errno=0;
                   9323:     dval=strtod(strb,&endptr); 
                   9324:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9325:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9326:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9327:       fflush(ficlog);
                   9328:       return 1;
                   9329:     }
                   9330:     weight[i]=dval; 
                   9331:     strcpy(line,stra);
1.225     brouard  9332:     
1.223     brouard  9333:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9334:       cutv(stra, strb, line, ' '); 
                   9335:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9336:        lval=-1;
1.223     brouard  9337:       }else{
1.225     brouard  9338:        errno=0;
                   9339:        /* what_kind_of_number(strb); */
                   9340:        dval=strtod(strb,&endptr);
                   9341:        /* if(strb != endptr && *endptr == '\0') */
                   9342:        /*   dval=dlval; */
                   9343:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9344:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9345:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9346:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9347:          return 1;
                   9348:        }
                   9349:        coqvar[iv][i]=dval; 
1.226     brouard  9350:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9351:       }
                   9352:       strcpy(line,stra);
                   9353:     }/* end loop nqv */
1.136     brouard  9354:     
1.223     brouard  9355:     /* Covariate values */
1.136     brouard  9356:     for (j=ncovcol;j>=1;j--){
                   9357:       cutv(stra, strb,line,' '); 
1.223     brouard  9358:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9359:        lval=-1;
1.136     brouard  9360:       }else{
1.225     brouard  9361:        errno=0;
                   9362:        lval=strtol(strb,&endptr,10); 
                   9363:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9364:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9365:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9366:          return 1;
                   9367:        }
1.136     brouard  9368:       }
                   9369:       if(lval <-1 || lval >1){
1.225     brouard  9370:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9371:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9372:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9373:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9374:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9375:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9376:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9377:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9378:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9379:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9380:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9381:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9382:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9383:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9384:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9385:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9386:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9387:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9388:        return 1;
1.136     brouard  9389:       }
                   9390:       covar[j][i]=(double)(lval);
                   9391:       strcpy(line,stra);
                   9392:     }  
                   9393:     lstra=strlen(stra);
1.225     brouard  9394:     
1.136     brouard  9395:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9396:       stratrunc = &(stra[lstra-9]);
                   9397:       num[i]=atol(stratrunc);
                   9398:     }
                   9399:     else
                   9400:       num[i]=atol(stra);
                   9401:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9402:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9403:     
                   9404:     i=i+1;
                   9405:   } /* End loop reading  data */
1.225     brouard  9406:   
1.136     brouard  9407:   *imax=i-1; /* Number of individuals */
                   9408:   fclose(fic);
1.225     brouard  9409:   
1.136     brouard  9410:   return (0);
1.164     brouard  9411:   /* endread: */
1.225     brouard  9412:   printf("Exiting readdata: ");
                   9413:   fclose(fic);
                   9414:   return (1);
1.223     brouard  9415: }
1.126     brouard  9416: 
1.234     brouard  9417: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9418:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9419:   while (*p2 == ' ')
1.234     brouard  9420:     p2++; 
                   9421:   /* while ((*p1++ = *p2++) !=0) */
                   9422:   /*   ; */
                   9423:   /* do */
                   9424:   /*   while (*p2 == ' ') */
                   9425:   /*     p2++; */
                   9426:   /* while (*p1++ == *p2++); */
                   9427:   *stri=p2; 
1.145     brouard  9428: }
                   9429: 
1.235     brouard  9430: int decoderesult ( char resultline[], int nres)
1.230     brouard  9431: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9432: {
1.235     brouard  9433:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9434:   char resultsav[MAXLINE];
1.234     brouard  9435:   int resultmodel[MAXLINE];
                   9436:   int modelresult[MAXLINE];
1.230     brouard  9437:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9438: 
1.234     brouard  9439:   removefirstspace(&resultline);
1.233     brouard  9440:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9441: 
                   9442:   if (strstr(resultline,"v") !=0){
                   9443:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9444:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9445:     return 1;
                   9446:   }
                   9447:   trimbb(resultsav, resultline);
                   9448:   if (strlen(resultsav) >1){
                   9449:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9450:   }
1.253     brouard  9451:   if(j == 0){ /* Resultline but no = */
                   9452:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9453:     return (0);
                   9454:   }
                   9455:     
1.234     brouard  9456:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9457:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9458:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9459:   }
                   9460:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9461:     if(nbocc(resultsav,'=') >1){
                   9462:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9463:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9464:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9465:     }else
                   9466:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9467:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9468:     
1.230     brouard  9469:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9470:     Tvarsel[k]=atoi(strc);
                   9471:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9472:     /* cptcovsel++;     */
                   9473:     if (nbocc(stra,'=') >0)
                   9474:       strcpy(resultsav,stra); /* and analyzes it */
                   9475:   }
1.235     brouard  9476:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9477:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9478:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9479:       match=0;
1.236     brouard  9480:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9481:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9482:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9483:          match=1;
                   9484:          break;
                   9485:        }
                   9486:       }
                   9487:       if(match == 0){
                   9488:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9489:       }
                   9490:     }
                   9491:   }
1.235     brouard  9492:   /* Checking for missing or useless values in comparison of current model needs */
                   9493:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9494:     match=0;
1.235     brouard  9495:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9496:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9497:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9498:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9499:          ++match;
                   9500:        }
                   9501:       }
                   9502:     }
                   9503:     if(match == 0){
                   9504:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9505:     }else if(match > 1){
                   9506:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9507:     }
                   9508:   }
1.235     brouard  9509:       
1.234     brouard  9510:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9511:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9512:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9513:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9514:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9515:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9516:   /*    1 0 0 0 */
                   9517:   /*    2 1 0 0 */
                   9518:   /*    3 0 1 0 */ 
                   9519:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9520:   /*    5 0 0 1 */
                   9521:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9522:   /*    7 0 1 1 */
                   9523:   /*    8 1 1 1 */
1.237     brouard  9524:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9525:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9526:   /* V5*age V5 known which value for nres?  */
                   9527:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9528:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9529:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9530:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9531:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9532:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9533:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9534:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9535:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9536:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9537:       k4++;;
                   9538:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9539:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9540:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9541:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9542:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9543:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9544:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9545:       k4q++;;
                   9546:     }
                   9547:   }
1.234     brouard  9548:   
1.235     brouard  9549:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9550:   return (0);
                   9551: }
1.235     brouard  9552: 
1.230     brouard  9553: int decodemodel( char model[], int lastobs)
                   9554:  /**< This routine decodes the model and returns:
1.224     brouard  9555:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9556:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9557:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9558:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9559:        * - cptcovage number of covariates with age*products =2
                   9560:        * - cptcovs number of simple covariates
                   9561:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9562:        *     which is a new column after the 9 (ncovcol) variables. 
                   9563:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9564:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9565:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9566:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9567:        */
1.136     brouard  9568: {
1.238     brouard  9569:   int i, j, k, ks, v;
1.227     brouard  9570:   int  j1, k1, k2, k3, k4;
1.136     brouard  9571:   char modelsav[80];
1.145     brouard  9572:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9573:   char *strpt;
1.136     brouard  9574: 
1.145     brouard  9575:   /*removespace(model);*/
1.136     brouard  9576:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9577:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9578:     if (strstr(model,"AGE") !=0){
1.192     brouard  9579:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9580:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9581:       return 1;
                   9582:     }
1.141     brouard  9583:     if (strstr(model,"v") !=0){
                   9584:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9585:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9586:       return 1;
                   9587:     }
1.187     brouard  9588:     strcpy(modelsav,model); 
                   9589:     if ((strpt=strstr(model,"age*age")) !=0){
                   9590:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9591:       if(strpt != model){
1.234     brouard  9592:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9593:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9594:  corresponding column of parameters.\n",model);
1.234     brouard  9595:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9596:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9597:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9598:        return 1;
1.225     brouard  9599:       }
1.187     brouard  9600:       nagesqr=1;
                   9601:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9602:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9603:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9604:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9605:       else 
1.234     brouard  9606:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9607:     }else
                   9608:       nagesqr=0;
                   9609:     if (strlen(modelsav) >1){
                   9610:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9611:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9612:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9613:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9614:                     * cst, age and age*age 
                   9615:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9616:       /* including age products which are counted in cptcovage.
                   9617:        * but the covariates which are products must be treated 
                   9618:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9619:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9620:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9621:       
                   9622:       
1.187     brouard  9623:       /*   Design
                   9624:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9625:        *  <          ncovcol=8                >
                   9626:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9627:        *   k=  1    2      3       4     5       6      7        8
                   9628:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9629:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9630:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9631:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9632:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9633:        *  Tage[++cptcovage]=k
                   9634:        *       if products, new covar are created after ncovcol with k1
                   9635:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9636:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9637:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9638:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9639:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9640:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9641:        *  <          ncovcol=8                >
                   9642:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9643:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9644:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9645:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9646:        * p Tprod[1]@2={                         6, 5}
                   9647:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9648:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9649:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9650:        *How to reorganize?
                   9651:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9652:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9653:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9654:        * Struct []
                   9655:        */
1.225     brouard  9656:       
1.187     brouard  9657:       /* This loop fills the array Tvar from the string 'model'.*/
                   9658:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9659:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9660:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9661:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9662:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9663:       /*       k=1 Tvar[1]=2 (from V2) */
                   9664:       /*       k=5 Tvar[5] */
                   9665:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9666:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9667:       /*       } */
1.198     brouard  9668:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9669:       /*
                   9670:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9671:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9672:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9673:       }
1.187     brouard  9674:       cptcovage=0;
                   9675:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9676:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9677:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9678:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9679:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9680:        /*scanf("%d",i);*/
                   9681:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9682:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9683:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9684:            /* covar is not filled and then is empty */
                   9685:            cptcovprod--;
                   9686:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9687:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9688:            Typevar[k]=1;  /* 1 for age product */
                   9689:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9690:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9691:            /*printf("stre=%s ", stre);*/
                   9692:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9693:            cptcovprod--;
                   9694:            cutl(stre,strb,strc,'V');
                   9695:            Tvar[k]=atoi(stre);
                   9696:            Typevar[k]=1;  /* 1 for age product */
                   9697:            cptcovage++;
                   9698:            Tage[cptcovage]=k;
                   9699:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9700:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9701:            cptcovn++;
                   9702:            cptcovprodnoage++;k1++;
                   9703:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9704:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9705:                                                because this model-covariate is a construction we invent a new column
                   9706:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9707:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9708:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9709:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9710:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9711:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9712:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9713:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9714:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9715:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9716:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9717:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9718:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9719:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9720:            for (i=1; i<=lastobs;i++){
                   9721:              /* Computes the new covariate which is a product of
                   9722:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9723:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9724:            }
                   9725:          } /* End age is not in the model */
                   9726:        } /* End if model includes a product */
                   9727:        else { /* no more sum */
                   9728:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9729:          /*  scanf("%d",i);*/
                   9730:          cutl(strd,strc,strb,'V');
                   9731:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9732:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9733:          Tvar[k]=atoi(strd);
                   9734:          Typevar[k]=0;  /* 0 for simple covariates */
                   9735:        }
                   9736:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9737:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9738:                                  scanf("%d",i);*/
1.187     brouard  9739:       } /* end of loop + on total covariates */
                   9740:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9741:   } /* end if strlen(model == 0) */
1.136     brouard  9742:   
                   9743:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9744:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9745:   
1.136     brouard  9746:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9747:      printf("cptcovprod=%d ", cptcovprod);
                   9748:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9749:      scanf("%d ",i);*/
                   9750: 
                   9751: 
1.230     brouard  9752: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9753:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9754: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9755:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9756:    k =           1    2   3     4       5       6      7      8        9
                   9757:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9758:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9759:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9760:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9761:          Tmodelind[combination of covar]=k;
1.225     brouard  9762: */  
                   9763: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9764:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9765:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9766:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9767:   printf("Model=%s\n\
                   9768: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9769: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9770: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9771:   fprintf(ficlog,"Model=%s\n\
                   9772: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9773: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9774: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  9775:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9776:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9777:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9778:       Fixed[k]= 0;
                   9779:       Dummy[k]= 0;
1.225     brouard  9780:       ncoveff++;
1.232     brouard  9781:       ncovf++;
1.234     brouard  9782:       nsd++;
                   9783:       modell[k].maintype= FTYPE;
                   9784:       TvarsD[nsd]=Tvar[k];
                   9785:       TvarsDind[nsd]=k;
                   9786:       TvarF[ncovf]=Tvar[k];
                   9787:       TvarFind[ncovf]=k;
                   9788:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9789:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9790:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9791:       Fixed[k]= 0;
                   9792:       Dummy[k]= 0;
                   9793:       ncoveff++;
                   9794:       ncovf++;
                   9795:       modell[k].maintype= FTYPE;
                   9796:       TvarF[ncovf]=Tvar[k];
                   9797:       TvarFind[ncovf]=k;
1.230     brouard  9798:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9799:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9800:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9801:       Fixed[k]= 0;
                   9802:       Dummy[k]= 1;
1.230     brouard  9803:       nqfveff++;
1.234     brouard  9804:       modell[k].maintype= FTYPE;
                   9805:       modell[k].subtype= FQ;
                   9806:       nsq++;
                   9807:       TvarsQ[nsq]=Tvar[k];
                   9808:       TvarsQind[nsq]=k;
1.232     brouard  9809:       ncovf++;
1.234     brouard  9810:       TvarF[ncovf]=Tvar[k];
                   9811:       TvarFind[ncovf]=k;
1.231     brouard  9812:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9813:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9814:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9815:       Fixed[k]= 1;
                   9816:       Dummy[k]= 0;
1.225     brouard  9817:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9818:       modell[k].maintype= VTYPE;
                   9819:       modell[k].subtype= VD;
                   9820:       nsd++;
                   9821:       TvarsD[nsd]=Tvar[k];
                   9822:       TvarsDind[nsd]=k;
                   9823:       ncovv++; /* Only simple time varying variables */
                   9824:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9825:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9826:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9827:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9828:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9829:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9830:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9831:       Fixed[k]= 1;
                   9832:       Dummy[k]= 1;
                   9833:       nqtveff++;
                   9834:       modell[k].maintype= VTYPE;
                   9835:       modell[k].subtype= VQ;
                   9836:       ncovv++; /* Only simple time varying variables */
                   9837:       nsq++;
                   9838:       TvarsQ[nsq]=Tvar[k];
                   9839:       TvarsQind[nsq]=k;
                   9840:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9841:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9842:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9843:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9844:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9845:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9846:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9847:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9848:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9849:       ncova++;
                   9850:       TvarA[ncova]=Tvar[k];
                   9851:       TvarAind[ncova]=k;
1.231     brouard  9852:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9853:        Fixed[k]= 2;
                   9854:        Dummy[k]= 2;
                   9855:        modell[k].maintype= ATYPE;
                   9856:        modell[k].subtype= APFD;
                   9857:        /* ncoveff++; */
1.227     brouard  9858:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9859:        Fixed[k]= 2;
                   9860:        Dummy[k]= 3;
                   9861:        modell[k].maintype= ATYPE;
                   9862:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9863:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9864:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9865:        Fixed[k]= 3;
                   9866:        Dummy[k]= 2;
                   9867:        modell[k].maintype= ATYPE;
                   9868:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9869:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9870:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9871:        Fixed[k]= 3;
                   9872:        Dummy[k]= 3;
                   9873:        modell[k].maintype= ATYPE;
                   9874:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9875:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9876:       }
                   9877:     }else if (Typevar[k] == 2) {  /* product without age */
                   9878:       k1=Tposprod[k];
                   9879:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9880:        if(Tvard[k1][2] <=ncovcol){
                   9881:          Fixed[k]= 1;
                   9882:          Dummy[k]= 0;
                   9883:          modell[k].maintype= FTYPE;
                   9884:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9885:          ncovf++; /* Fixed variables without age */
                   9886:          TvarF[ncovf]=Tvar[k];
                   9887:          TvarFind[ncovf]=k;
                   9888:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9889:          Fixed[k]= 0;  /* or 2 ?*/
                   9890:          Dummy[k]= 1;
                   9891:          modell[k].maintype= FTYPE;
                   9892:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9893:          ncovf++; /* Varying variables without age */
                   9894:          TvarF[ncovf]=Tvar[k];
                   9895:          TvarFind[ncovf]=k;
                   9896:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9897:          Fixed[k]= 1;
                   9898:          Dummy[k]= 0;
                   9899:          modell[k].maintype= VTYPE;
                   9900:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9901:          ncovv++; /* Varying variables without age */
                   9902:          TvarV[ncovv]=Tvar[k];
                   9903:          TvarVind[ncovv]=k;
                   9904:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9905:          Fixed[k]= 1;
                   9906:          Dummy[k]= 1;
                   9907:          modell[k].maintype= VTYPE;
                   9908:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9909:          ncovv++; /* Varying variables without age */
                   9910:          TvarV[ncovv]=Tvar[k];
                   9911:          TvarVind[ncovv]=k;
                   9912:        }
1.227     brouard  9913:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9914:        if(Tvard[k1][2] <=ncovcol){
                   9915:          Fixed[k]= 0;  /* or 2 ?*/
                   9916:          Dummy[k]= 1;
                   9917:          modell[k].maintype= FTYPE;
                   9918:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9919:          ncovf++; /* Fixed variables without age */
                   9920:          TvarF[ncovf]=Tvar[k];
                   9921:          TvarFind[ncovf]=k;
                   9922:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9923:          Fixed[k]= 1;
                   9924:          Dummy[k]= 1;
                   9925:          modell[k].maintype= VTYPE;
                   9926:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9927:          ncovv++; /* Varying variables without age */
                   9928:          TvarV[ncovv]=Tvar[k];
                   9929:          TvarVind[ncovv]=k;
                   9930:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9931:          Fixed[k]= 1;
                   9932:          Dummy[k]= 1;
                   9933:          modell[k].maintype= VTYPE;
                   9934:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9935:          ncovv++; /* Varying variables without age */
                   9936:          TvarV[ncovv]=Tvar[k];
                   9937:          TvarVind[ncovv]=k;
                   9938:          ncovv++; /* Varying variables without age */
                   9939:          TvarV[ncovv]=Tvar[k];
                   9940:          TvarVind[ncovv]=k;
                   9941:        }
1.227     brouard  9942:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9943:        if(Tvard[k1][2] <=ncovcol){
                   9944:          Fixed[k]= 1;
                   9945:          Dummy[k]= 1;
                   9946:          modell[k].maintype= VTYPE;
                   9947:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9948:          ncovv++; /* Varying variables without age */
                   9949:          TvarV[ncovv]=Tvar[k];
                   9950:          TvarVind[ncovv]=k;
                   9951:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9952:          Fixed[k]= 1;
                   9953:          Dummy[k]= 1;
                   9954:          modell[k].maintype= VTYPE;
                   9955:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9956:          ncovv++; /* Varying variables without age */
                   9957:          TvarV[ncovv]=Tvar[k];
                   9958:          TvarVind[ncovv]=k;
                   9959:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9960:          Fixed[k]= 1;
                   9961:          Dummy[k]= 0;
                   9962:          modell[k].maintype= VTYPE;
                   9963:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9964:          ncovv++; /* Varying variables without age */
                   9965:          TvarV[ncovv]=Tvar[k];
                   9966:          TvarVind[ncovv]=k;
                   9967:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9968:          Fixed[k]= 1;
                   9969:          Dummy[k]= 1;
                   9970:          modell[k].maintype= VTYPE;
                   9971:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9972:          ncovv++; /* Varying variables without age */
                   9973:          TvarV[ncovv]=Tvar[k];
                   9974:          TvarVind[ncovv]=k;
                   9975:        }
1.227     brouard  9976:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9977:        if(Tvard[k1][2] <=ncovcol){
                   9978:          Fixed[k]= 1;
                   9979:          Dummy[k]= 1;
                   9980:          modell[k].maintype= VTYPE;
                   9981:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9982:          ncovv++; /* Varying variables without age */
                   9983:          TvarV[ncovv]=Tvar[k];
                   9984:          TvarVind[ncovv]=k;
                   9985:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9986:          Fixed[k]= 1;
                   9987:          Dummy[k]= 1;
                   9988:          modell[k].maintype= VTYPE;
                   9989:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9990:          ncovv++; /* Varying variables without age */
                   9991:          TvarV[ncovv]=Tvar[k];
                   9992:          TvarVind[ncovv]=k;
                   9993:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9994:          Fixed[k]= 1;
                   9995:          Dummy[k]= 1;
                   9996:          modell[k].maintype= VTYPE;
                   9997:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   9998:          ncovv++; /* Varying variables without age */
                   9999:          TvarV[ncovv]=Tvar[k];
                   10000:          TvarVind[ncovv]=k;
                   10001:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10002:          Fixed[k]= 1;
                   10003:          Dummy[k]= 1;
                   10004:          modell[k].maintype= VTYPE;
                   10005:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10006:          ncovv++; /* Varying variables without age */
                   10007:          TvarV[ncovv]=Tvar[k];
                   10008:          TvarVind[ncovv]=k;
                   10009:        }
1.227     brouard  10010:       }else{
1.240     brouard  10011:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10012:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10013:       } /*end k1*/
1.225     brouard  10014:     }else{
1.226     brouard  10015:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10016:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10017:     }
1.227     brouard  10018:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10019:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10020:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10021:   }
                   10022:   /* Searching for doublons in the model */
                   10023:   for(k1=1; k1<= cptcovt;k1++){
                   10024:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10025:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10026:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10027:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10028:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10029:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10030:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10031:            return(1);
                   10032:          }
                   10033:        }else if (Typevar[k1] ==2){
                   10034:          k3=Tposprod[k1];
                   10035:          k4=Tposprod[k2];
                   10036:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10037:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10038:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10039:            return(1);
                   10040:          }
                   10041:        }
1.227     brouard  10042:       }
                   10043:     }
1.225     brouard  10044:   }
                   10045:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10046:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10047:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10048:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10049:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10050:   /*endread:*/
1.225     brouard  10051:   printf("Exiting decodemodel: ");
                   10052:   return (1);
1.136     brouard  10053: }
                   10054: 
1.169     brouard  10055: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10056: {/* Check ages at death */
1.136     brouard  10057:   int i, m;
1.218     brouard  10058:   int firstone=0;
                   10059:   
1.136     brouard  10060:   for (i=1; i<=imx; i++) {
                   10061:     for(m=2; (m<= maxwav); m++) {
                   10062:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10063:        anint[m][i]=9999;
1.216     brouard  10064:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10065:          s[m][i]=-1;
1.136     brouard  10066:       }
                   10067:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10068:        *nberr = *nberr + 1;
1.218     brouard  10069:        if(firstone == 0){
                   10070:          firstone=1;
1.260     brouard  10071:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10072:        }
1.262     brouard  10073:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10074:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10075:       }
                   10076:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10077:        (*nberr)++;
1.259     brouard  10078:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10079:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10080:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10081:       }
                   10082:     }
                   10083:   }
                   10084: 
                   10085:   for (i=1; i<=imx; i++)  {
                   10086:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10087:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10088:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10089:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10090:          if(agedc[i]>0){
                   10091:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10092:              agev[m][i]=agedc[i];
1.214     brouard  10093:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10094:            }else {
1.136     brouard  10095:              if ((int)andc[i]!=9999){
                   10096:                nbwarn++;
                   10097:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10098:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10099:                agev[m][i]=-1;
                   10100:              }
                   10101:            }
1.169     brouard  10102:          } /* agedc > 0 */
1.214     brouard  10103:        } /* end if */
1.136     brouard  10104:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10105:                                 years but with the precision of a month */
                   10106:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10107:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10108:            agev[m][i]=1;
                   10109:          else if(agev[m][i] < *agemin){ 
                   10110:            *agemin=agev[m][i];
                   10111:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10112:          }
                   10113:          else if(agev[m][i] >*agemax){
                   10114:            *agemax=agev[m][i];
1.156     brouard  10115:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10116:          }
                   10117:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10118:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10119:        } /* en if 9*/
1.136     brouard  10120:        else { /* =9 */
1.214     brouard  10121:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10122:          agev[m][i]=1;
                   10123:          s[m][i]=-1;
                   10124:        }
                   10125:       }
1.214     brouard  10126:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10127:        agev[m][i]=1;
1.214     brouard  10128:       else{
                   10129:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10130:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10131:        agev[m][i]=0;
                   10132:       }
                   10133:     } /* End for lastpass */
                   10134:   }
1.136     brouard  10135:     
                   10136:   for (i=1; i<=imx; i++)  {
                   10137:     for(m=firstpass; (m<=lastpass); m++){
                   10138:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10139:        (*nberr)++;
1.136     brouard  10140:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10141:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10142:        return 1;
                   10143:       }
                   10144:     }
                   10145:   }
                   10146: 
                   10147:   /*for (i=1; i<=imx; i++){
                   10148:   for (m=firstpass; (m<lastpass); m++){
                   10149:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10150: }
                   10151: 
                   10152: }*/
                   10153: 
                   10154: 
1.139     brouard  10155:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10156:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10157: 
                   10158:   return (0);
1.164     brouard  10159:  /* endread:*/
1.136     brouard  10160:     printf("Exiting calandcheckages: ");
                   10161:     return (1);
                   10162: }
                   10163: 
1.172     brouard  10164: #if defined(_MSC_VER)
                   10165: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10166: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10167: //#include "stdafx.h"
                   10168: //#include <stdio.h>
                   10169: //#include <tchar.h>
                   10170: //#include <windows.h>
                   10171: //#include <iostream>
                   10172: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10173: 
                   10174: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10175: 
                   10176: BOOL IsWow64()
                   10177: {
                   10178:        BOOL bIsWow64 = FALSE;
                   10179: 
                   10180:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10181:        //  (HANDLE, PBOOL);
                   10182: 
                   10183:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10184: 
                   10185:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10186:        const char funcName[] = "IsWow64Process";
                   10187:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10188:                GetProcAddress(module, funcName);
                   10189: 
                   10190:        if (NULL != fnIsWow64Process)
                   10191:        {
                   10192:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10193:                        &bIsWow64))
                   10194:                        //throw std::exception("Unknown error");
                   10195:                        printf("Unknown error\n");
                   10196:        }
                   10197:        return bIsWow64 != FALSE;
                   10198: }
                   10199: #endif
1.177     brouard  10200: 
1.191     brouard  10201: void syscompilerinfo(int logged)
1.292   ! brouard  10202: {
        !          10203: #include <stdint.h>
        !          10204: 
        !          10205:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10206:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10207:    /* /GS /W3 /Gy
                   10208:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10209:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10210:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10211:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10212:    */ 
                   10213:    /* 64 bits */
1.185     brouard  10214:    /*
                   10215:      /GS /W3 /Gy
                   10216:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10217:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10218:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10219:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10220:    /* Optimization are useless and O3 is slower than O2 */
                   10221:    /*
                   10222:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10223:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10224:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10225:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10226:    */
1.186     brouard  10227:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10228:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10229:       /PDB:"visual studio
                   10230:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10231:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10232:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10233:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10234:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10235:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10236:       uiAccess='false'"
                   10237:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10238:       /NOLOGO /TLBID:1
                   10239:    */
1.292   ! brouard  10240: 
        !          10241: 
1.177     brouard  10242: #if defined __INTEL_COMPILER
1.178     brouard  10243: #if defined(__GNUC__)
                   10244:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10245: #endif
1.177     brouard  10246: #elif defined(__GNUC__) 
1.179     brouard  10247: #ifndef  __APPLE__
1.174     brouard  10248: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10249: #endif
1.177     brouard  10250:    struct utsname sysInfo;
1.178     brouard  10251:    int cross = CROSS;
                   10252:    if (cross){
                   10253:           printf("Cross-");
1.191     brouard  10254:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10255:    }
1.174     brouard  10256: #endif
                   10257: 
1.191     brouard  10258:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10259: #if defined(__clang__)
1.191     brouard  10260:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10261: #endif
                   10262: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10263:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10264: #endif
                   10265: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10266:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10267: #endif
                   10268: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10269:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10270: #endif
                   10271: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10272:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10273: #endif
                   10274: #if defined(_MSC_VER)
1.191     brouard  10275:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10276: #endif
                   10277: #if defined(__PGI)
1.191     brouard  10278:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10279: #endif
                   10280: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10281:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10282: #endif
1.191     brouard  10283:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10284:    
1.167     brouard  10285: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10286: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10287:     // Windows (x64 and x86)
1.191     brouard  10288:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10289: #elif __unix__ // all unices, not all compilers
                   10290:     // Unix
1.191     brouard  10291:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10292: #elif __linux__
                   10293:     // linux
1.191     brouard  10294:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10295: #elif __APPLE__
1.174     brouard  10296:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10297:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10298: #endif
                   10299: 
                   10300: /*  __MINGW32__          */
                   10301: /*  __CYGWIN__  */
                   10302: /* __MINGW64__  */
                   10303: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10304: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10305: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10306: /* _WIN64  // Defined for applications for Win64. */
                   10307: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10308: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10309: 
1.167     brouard  10310: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10311:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10312: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10313:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10314: #else
1.191     brouard  10315:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10316: #endif
                   10317: 
1.169     brouard  10318: #if defined(__GNUC__)
                   10319: # if defined(__GNUC_PATCHLEVEL__)
                   10320: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10321:                             + __GNUC_MINOR__ * 100 \
                   10322:                             + __GNUC_PATCHLEVEL__)
                   10323: # else
                   10324: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10325:                             + __GNUC_MINOR__ * 100)
                   10326: # endif
1.174     brouard  10327:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10328:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10329: 
                   10330:    if (uname(&sysInfo) != -1) {
                   10331:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10332:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10333:    }
                   10334:    else
                   10335:       perror("uname() error");
1.179     brouard  10336:    //#ifndef __INTEL_COMPILER 
                   10337: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10338:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10339:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10340: #endif
1.169     brouard  10341: #endif
1.172     brouard  10342: 
1.286     brouard  10343:    //   void main ()
1.172     brouard  10344:    //   {
1.169     brouard  10345: #if defined(_MSC_VER)
1.174     brouard  10346:    if (IsWow64()){
1.191     brouard  10347:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10348:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10349:    }
                   10350:    else{
1.191     brouard  10351:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10352:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10353:    }
1.172     brouard  10354:    //     printf("\nPress Enter to continue...");
                   10355:    //     getchar();
                   10356:    //   }
                   10357: 
1.169     brouard  10358: #endif
                   10359:    
1.167     brouard  10360: 
1.219     brouard  10361: }
1.136     brouard  10362: 
1.219     brouard  10363: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10364:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10365:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10366:   /* double ftolpl = 1.e-10; */
1.180     brouard  10367:   double age, agebase, agelim;
1.203     brouard  10368:   double tot;
1.180     brouard  10369: 
1.202     brouard  10370:   strcpy(filerespl,"PL_");
                   10371:   strcat(filerespl,fileresu);
                   10372:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10373:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10374:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10375:   }
1.288     brouard  10376:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10377:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10378:   pstamp(ficrespl);
1.288     brouard  10379:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10380:   fprintf(ficrespl,"#Age ");
                   10381:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10382:   fprintf(ficrespl,"\n");
1.180     brouard  10383:   
1.219     brouard  10384:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10385: 
1.219     brouard  10386:   agebase=ageminpar;
                   10387:   agelim=agemaxpar;
1.180     brouard  10388: 
1.227     brouard  10389:   /* i1=pow(2,ncoveff); */
1.234     brouard  10390:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10391:   if (cptcovn < 1){i1=1;}
1.180     brouard  10392: 
1.238     brouard  10393:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10394:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10395:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10396:        continue;
1.235     brouard  10397: 
1.238     brouard  10398:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10399:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10400:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10401:       /* k=k+1; */
                   10402:       /* to clean */
                   10403:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10404:       fprintf(ficrespl,"#******");
                   10405:       printf("#******");
                   10406:       fprintf(ficlog,"#******");
                   10407:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10408:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10409:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10410:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10411:       }
                   10412:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10413:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10414:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10415:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10416:       }
                   10417:       fprintf(ficrespl,"******\n");
                   10418:       printf("******\n");
                   10419:       fprintf(ficlog,"******\n");
                   10420:       if(invalidvarcomb[k]){
                   10421:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10422:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10423:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10424:        continue;
                   10425:       }
1.219     brouard  10426: 
1.238     brouard  10427:       fprintf(ficrespl,"#Age ");
                   10428:       for(j=1;j<=cptcoveff;j++) {
                   10429:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10430:       }
                   10431:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10432:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10433:     
1.238     brouard  10434:       for (age=agebase; age<=agelim; age++){
                   10435:        /* for (age=agebase; age<=agebase; age++){ */
                   10436:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10437:        fprintf(ficrespl,"%.0f ",age );
                   10438:        for(j=1;j<=cptcoveff;j++)
                   10439:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10440:        tot=0.;
                   10441:        for(i=1; i<=nlstate;i++){
                   10442:          tot +=  prlim[i][i];
                   10443:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10444:        }
                   10445:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10446:       } /* Age */
                   10447:       /* was end of cptcod */
                   10448:     } /* cptcov */
                   10449:   } /* nres */
1.219     brouard  10450:   return 0;
1.180     brouard  10451: }
                   10452: 
1.218     brouard  10453: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10454:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10455:        
                   10456:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10457:    * at any age between ageminpar and agemaxpar
                   10458:         */
1.235     brouard  10459:   int i, j, k, i1, nres=0 ;
1.217     brouard  10460:   /* double ftolpl = 1.e-10; */
                   10461:   double age, agebase, agelim;
                   10462:   double tot;
1.218     brouard  10463:   /* double ***mobaverage; */
                   10464:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10465: 
                   10466:   strcpy(fileresplb,"PLB_");
                   10467:   strcat(fileresplb,fileresu);
                   10468:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10469:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10470:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10471:   }
1.288     brouard  10472:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10473:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10474:   pstamp(ficresplb);
1.288     brouard  10475:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10476:   fprintf(ficresplb,"#Age ");
                   10477:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10478:   fprintf(ficresplb,"\n");
                   10479:   
1.218     brouard  10480:   
                   10481:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10482:   
                   10483:   agebase=ageminpar;
                   10484:   agelim=agemaxpar;
                   10485:   
                   10486:   
1.227     brouard  10487:   i1=pow(2,cptcoveff);
1.218     brouard  10488:   if (cptcovn < 1){i1=1;}
1.227     brouard  10489:   
1.238     brouard  10490:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10491:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10492:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10493:        continue;
                   10494:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10495:       fprintf(ficresplb,"#******");
                   10496:       printf("#******");
                   10497:       fprintf(ficlog,"#******");
                   10498:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10499:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10500:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10501:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10502:       }
                   10503:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10504:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10505:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10506:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10507:       }
                   10508:       fprintf(ficresplb,"******\n");
                   10509:       printf("******\n");
                   10510:       fprintf(ficlog,"******\n");
                   10511:       if(invalidvarcomb[k]){
                   10512:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10513:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10514:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10515:        continue;
                   10516:       }
1.218     brouard  10517:     
1.238     brouard  10518:       fprintf(ficresplb,"#Age ");
                   10519:       for(j=1;j<=cptcoveff;j++) {
                   10520:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10521:       }
                   10522:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10523:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10524:     
                   10525:     
1.238     brouard  10526:       for (age=agebase; age<=agelim; age++){
                   10527:        /* for (age=agebase; age<=agebase; age++){ */
                   10528:        if(mobilavproj > 0){
                   10529:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10530:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10531:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10532:        }else if (mobilavproj == 0){
                   10533:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10534:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10535:          exit(1);
                   10536:        }else{
                   10537:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10538:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10539:          /* printf("TOTOT\n"); */
                   10540:           /* exit(1); */
1.238     brouard  10541:        }
                   10542:        fprintf(ficresplb,"%.0f ",age );
                   10543:        for(j=1;j<=cptcoveff;j++)
                   10544:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10545:        tot=0.;
                   10546:        for(i=1; i<=nlstate;i++){
                   10547:          tot +=  bprlim[i][i];
                   10548:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10549:        }
                   10550:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10551:       } /* Age */
                   10552:       /* was end of cptcod */
1.255     brouard  10553:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10554:     } /* end of any combination */
                   10555:   } /* end of nres */  
1.218     brouard  10556:   /* hBijx(p, bage, fage); */
                   10557:   /* fclose(ficrespijb); */
                   10558:   
                   10559:   return 0;
1.217     brouard  10560: }
1.218     brouard  10561:  
1.180     brouard  10562: int hPijx(double *p, int bage, int fage){
                   10563:     /*------------- h Pij x at various ages ------------*/
                   10564: 
                   10565:   int stepsize;
                   10566:   int agelim;
                   10567:   int hstepm;
                   10568:   int nhstepm;
1.235     brouard  10569:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10570: 
                   10571:   double agedeb;
                   10572:   double ***p3mat;
                   10573: 
1.201     brouard  10574:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10575:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10576:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10577:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10578:     }
                   10579:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10580:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10581:   
                   10582:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10583:     /*if (stepm<=24) stepsize=2;*/
                   10584: 
                   10585:     agelim=AGESUP;
                   10586:     hstepm=stepsize*YEARM; /* Every year of age */
                   10587:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10588:                
1.180     brouard  10589:     /* hstepm=1;   aff par mois*/
                   10590:     pstamp(ficrespij);
                   10591:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10592:     i1= pow(2,cptcoveff);
1.218     brouard  10593:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10594:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10595:                /*      k=k+1;  */
1.235     brouard  10596:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10597:     for(k=1; k<=i1;k++){
1.253     brouard  10598:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10599:        continue;
1.183     brouard  10600:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10601:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10602:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10603:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10604:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10605:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10606:       }
1.183     brouard  10607:       fprintf(ficrespij,"******\n");
                   10608:       
                   10609:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10610:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10611:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10612:        
                   10613:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10614:        
1.183     brouard  10615:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10616:        oldm=oldms;savm=savms;
1.235     brouard  10617:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10618:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10619:        for(i=1; i<=nlstate;i++)
                   10620:          for(j=1; j<=nlstate+ndeath;j++)
                   10621:            fprintf(ficrespij," %1d-%1d",i,j);
                   10622:        fprintf(ficrespij,"\n");
                   10623:        for (h=0; h<=nhstepm; h++){
                   10624:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10625:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10626:          for(i=1; i<=nlstate;i++)
                   10627:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10628:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10629:          fprintf(ficrespij,"\n");
                   10630:        }
1.183     brouard  10631:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10632:        fprintf(ficrespij,"\n");
                   10633:       }
1.180     brouard  10634:       /*}*/
                   10635:     }
1.218     brouard  10636:     return 0;
1.180     brouard  10637: }
1.218     brouard  10638:  
                   10639:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10640:     /*------------- h Bij x at various ages ------------*/
                   10641: 
                   10642:   int stepsize;
1.218     brouard  10643:   /* int agelim; */
                   10644:        int ageminl;
1.217     brouard  10645:   int hstepm;
                   10646:   int nhstepm;
1.238     brouard  10647:   int h, i, i1, j, k, nres;
1.218     brouard  10648:        
1.217     brouard  10649:   double agedeb;
                   10650:   double ***p3mat;
1.218     brouard  10651:        
                   10652:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10653:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10654:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10655:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10656:   }
                   10657:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10658:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10659:   
                   10660:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10661:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10662:   
1.218     brouard  10663:   /* agelim=AGESUP; */
1.289     brouard  10664:   ageminl=AGEINF; /* was 30 */
1.218     brouard  10665:   hstepm=stepsize*YEARM; /* Every year of age */
                   10666:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10667:   
                   10668:   /* hstepm=1;   aff par mois*/
                   10669:   pstamp(ficrespijb);
1.255     brouard  10670:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10671:   i1= pow(2,cptcoveff);
1.218     brouard  10672:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10673:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10674:   /*   k=k+1;  */
1.238     brouard  10675:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10676:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10677:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10678:        continue;
                   10679:       fprintf(ficrespijb,"\n#****** ");
                   10680:       for(j=1;j<=cptcoveff;j++)
                   10681:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10682:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10683:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10684:       }
                   10685:       fprintf(ficrespijb,"******\n");
1.264     brouard  10686:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10687:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10688:        continue;
                   10689:       }
                   10690:       
                   10691:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10692:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10693:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10694:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10695:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10696:        
                   10697:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10698:        
1.266     brouard  10699:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10700:        /* and memory limitations if stepm is small */
                   10701: 
1.238     brouard  10702:        /* oldm=oldms;savm=savms; */
                   10703:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10704:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10705:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10706:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10707:        for(i=1; i<=nlstate;i++)
                   10708:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10709:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10710:        fprintf(ficrespijb,"\n");
1.238     brouard  10711:        for (h=0; h<=nhstepm; h++){
                   10712:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10713:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10714:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10715:          for(i=1; i<=nlstate;i++)
                   10716:            for(j=1; j<=nlstate+ndeath;j++)
                   10717:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10718:          fprintf(ficrespijb,"\n");
                   10719:        }
                   10720:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10721:        fprintf(ficrespijb,"\n");
                   10722:       } /* end age deb */
                   10723:     } /* end combination */
                   10724:   } /* end nres */
1.218     brouard  10725:   return 0;
                   10726:  } /*  hBijx */
1.217     brouard  10727: 
1.180     brouard  10728: 
1.136     brouard  10729: /***********************************************/
                   10730: /**************** Main Program *****************/
                   10731: /***********************************************/
                   10732: 
                   10733: int main(int argc, char *argv[])
                   10734: {
                   10735: #ifdef GSL
                   10736:   const gsl_multimin_fminimizer_type *T;
                   10737:   size_t iteri = 0, it;
                   10738:   int rval = GSL_CONTINUE;
                   10739:   int status = GSL_SUCCESS;
                   10740:   double ssval;
                   10741: #endif
                   10742:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  10743:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   10744:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  10745:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10746:   int jj, ll, li, lj, lk;
1.136     brouard  10747:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10748:   int num_filled;
1.136     brouard  10749:   int itimes;
                   10750:   int NDIM=2;
                   10751:   int vpopbased=0;
1.235     brouard  10752:   int nres=0;
1.258     brouard  10753:   int endishere=0;
1.277     brouard  10754:   int noffset=0;
1.274     brouard  10755:   int ncurrv=0; /* Temporary variable */
                   10756:   
1.164     brouard  10757:   char ca[32], cb[32];
1.136     brouard  10758:   /*  FILE *fichtm; *//* Html File */
                   10759:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10760:   struct stat info;
1.191     brouard  10761:   double agedeb=0.;
1.194     brouard  10762: 
                   10763:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10764:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10765: 
1.165     brouard  10766:   double fret;
1.191     brouard  10767:   double dum=0.; /* Dummy variable */
1.136     brouard  10768:   double ***p3mat;
1.218     brouard  10769:   /* double ***mobaverage; */
1.164     brouard  10770: 
                   10771:   char line[MAXLINE];
1.197     brouard  10772:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10773: 
1.234     brouard  10774:   char  modeltemp[MAXLINE];
1.230     brouard  10775:   char resultline[MAXLINE];
                   10776:   
1.136     brouard  10777:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10778:   char *tok, *val; /* pathtot */
1.290     brouard  10779:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  10780:   int c,  h , cpt, c2;
1.191     brouard  10781:   int jl=0;
                   10782:   int i1, j1, jk, stepsize=0;
1.194     brouard  10783:   int count=0;
                   10784: 
1.164     brouard  10785:   int *tab; 
1.136     brouard  10786:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.292   ! brouard  10787:   /* int backcast=0; */ /* defined as global for mlikeli and mle */
1.136     brouard  10788:   int mobilav=0,popforecast=0;
1.191     brouard  10789:   int hstepm=0, nhstepm=0;
1.136     brouard  10790:   int agemortsup;
                   10791:   float  sumlpop=0.;
                   10792:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10793:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10794: 
1.191     brouard  10795:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10796:   double ftolpl=FTOL;
                   10797:   double **prlim;
1.217     brouard  10798:   double **bprlim;
1.136     brouard  10799:   double ***param; /* Matrix of parameters */
1.251     brouard  10800:   double ***paramstart; /* Matrix of starting parameter values */
                   10801:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10802:   double **matcov; /* Matrix of covariance */
1.203     brouard  10803:   double **hess; /* Hessian matrix */
1.136     brouard  10804:   double ***delti3; /* Scale */
                   10805:   double *delti; /* Scale */
                   10806:   double ***eij, ***vareij;
                   10807:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10808: 
1.136     brouard  10809:   double *epj, vepp;
1.164     brouard  10810: 
1.273     brouard  10811:   double dateprev1, dateprev2;
                   10812:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0;
                   10813:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0;
1.217     brouard  10814: 
1.136     brouard  10815:   double **ximort;
1.145     brouard  10816:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10817:   int *dcwave;
                   10818: 
1.164     brouard  10819:   char z[1]="c";
1.136     brouard  10820: 
                   10821:   /*char  *strt;*/
                   10822:   char strtend[80];
1.126     brouard  10823: 
1.164     brouard  10824: 
1.126     brouard  10825: /*   setlocale (LC_ALL, ""); */
                   10826: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10827: /*   textdomain (PACKAGE); */
                   10828: /*   setlocale (LC_CTYPE, ""); */
                   10829: /*   setlocale (LC_MESSAGES, ""); */
                   10830: 
                   10831:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10832:   rstart_time = time(NULL);  
                   10833:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10834:   start_time = *localtime(&rstart_time);
1.126     brouard  10835:   curr_time=start_time;
1.157     brouard  10836:   /*tml = *localtime(&start_time.tm_sec);*/
                   10837:   /* strcpy(strstart,asctime(&tml)); */
                   10838:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10839: 
                   10840: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10841: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10842: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10843: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10844: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10845: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10846: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10847: /*   strt=asctime(&tmg); */
                   10848: /*   printf("Time(after) =%s",strstart);  */
                   10849: /*  (void) time (&time_value);
                   10850: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10851: *  tm = *localtime(&time_value);
                   10852: *  strstart=asctime(&tm);
                   10853: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10854: */
                   10855: 
                   10856:   nberr=0; /* Number of errors and warnings */
                   10857:   nbwarn=0;
1.184     brouard  10858: #ifdef WIN32
                   10859:   _getcwd(pathcd, size);
                   10860: #else
1.126     brouard  10861:   getcwd(pathcd, size);
1.184     brouard  10862: #endif
1.191     brouard  10863:   syscompilerinfo(0);
1.196     brouard  10864:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10865:   if(argc <=1){
                   10866:     printf("\nEnter the parameter file name: ");
1.205     brouard  10867:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10868:       printf("ERROR Empty parameter file name\n");
                   10869:       goto end;
                   10870:     }
1.126     brouard  10871:     i=strlen(pathr);
                   10872:     if(pathr[i-1]=='\n')
                   10873:       pathr[i-1]='\0';
1.156     brouard  10874:     i=strlen(pathr);
1.205     brouard  10875:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10876:       pathr[i-1]='\0';
1.205     brouard  10877:     }
                   10878:     i=strlen(pathr);
                   10879:     if( i==0 ){
                   10880:       printf("ERROR Empty parameter file name\n");
                   10881:       goto end;
                   10882:     }
                   10883:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10884:       printf("Pathr |%s|\n",pathr);
                   10885:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10886:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10887:       strcpy (pathtot, val);
                   10888:       if(pathr[0] == '\0') break; /* Dirty */
                   10889:     }
                   10890:   }
1.281     brouard  10891:   else if (argc<=2){
                   10892:     strcpy(pathtot,argv[1]);
                   10893:   }
1.126     brouard  10894:   else{
                   10895:     strcpy(pathtot,argv[1]);
1.281     brouard  10896:     strcpy(z,argv[2]);
                   10897:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  10898:   }
                   10899:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10900:   /*cygwin_split_path(pathtot,path,optionfile);
                   10901:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10902:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10903: 
                   10904:   /* Split argv[0], imach program to get pathimach */
                   10905:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10906:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10907:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10908:  /*   strcpy(pathimach,argv[0]); */
                   10909:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10910:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10911:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10912: #ifdef WIN32
                   10913:   _chdir(path); /* Can be a relative path */
                   10914:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10915: #else
1.126     brouard  10916:   chdir(path); /* Can be a relative path */
1.184     brouard  10917:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10918: #endif
                   10919:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10920:   strcpy(command,"mkdir ");
                   10921:   strcat(command,optionfilefiname);
                   10922:   if((outcmd=system(command)) != 0){
1.169     brouard  10923:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10924:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10925:     /* fclose(ficlog); */
                   10926: /*     exit(1); */
                   10927:   }
                   10928: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10929: /*     perror("mkdir"); */
                   10930: /*   } */
                   10931: 
                   10932:   /*-------- arguments in the command line --------*/
                   10933: 
1.186     brouard  10934:   /* Main Log file */
1.126     brouard  10935:   strcat(filelog, optionfilefiname);
                   10936:   strcat(filelog,".log");    /* */
                   10937:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10938:     printf("Problem with logfile %s\n",filelog);
                   10939:     goto end;
                   10940:   }
                   10941:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10942:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10943:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10944:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10945:  path=%s \n\
                   10946:  optionfile=%s\n\
                   10947:  optionfilext=%s\n\
1.156     brouard  10948:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10949: 
1.197     brouard  10950:   syscompilerinfo(1);
1.167     brouard  10951: 
1.126     brouard  10952:   printf("Local time (at start):%s",strstart);
                   10953:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10954:   fflush(ficlog);
                   10955: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10956: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10957: 
                   10958:   /* */
                   10959:   strcpy(fileres,"r");
                   10960:   strcat(fileres, optionfilefiname);
1.201     brouard  10961:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10962:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10963:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10964: 
1.186     brouard  10965:   /* Main ---------arguments file --------*/
1.126     brouard  10966: 
                   10967:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10968:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10969:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10970:     fflush(ficlog);
1.149     brouard  10971:     /* goto end; */
                   10972:     exit(70); 
1.126     brouard  10973:   }
                   10974: 
                   10975:   strcpy(filereso,"o");
1.201     brouard  10976:   strcat(filereso,fileresu);
1.126     brouard  10977:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10978:     printf("Problem with Output resultfile: %s\n", filereso);
                   10979:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10980:     fflush(ficlog);
                   10981:     goto end;
                   10982:   }
1.278     brouard  10983:       /*-------- Rewriting parameter file ----------*/
                   10984:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   10985:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   10986:   strcat(rfileres,".");    /* */
                   10987:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10988:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   10989:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10990:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   10991:     fflush(ficlog);
                   10992:     goto end;
                   10993:   }
                   10994:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  10995: 
1.278     brouard  10996:                                      
1.126     brouard  10997:   /* Reads comments: lines beginning with '#' */
                   10998:   numlinepar=0;
1.277     brouard  10999:   /* Is it a BOM UTF-8 Windows file? */
                   11000:   /* First parameter line */
1.197     brouard  11001:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11002:     noffset=0;
                   11003:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11004:     {
                   11005:       noffset=noffset+3;
                   11006:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11007:     }
                   11008:     else if( line[0] == (char)0xFE && line[1] == (char)0xFF)
                   11009:     {
                   11010:       noffset=noffset+2;
                   11011:       printf("# File is an UTF16BE BOM file\n");
                   11012:     }
                   11013:     else if( line[0] == 0 && line[1] == 0)
                   11014:     {
                   11015:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11016:        noffset=noffset+4;
                   11017:        printf("# File is an UTF16BE BOM file\n");
                   11018:       }
                   11019:     } else{
                   11020:       ;/*printf(" Not a BOM file\n");*/
                   11021:     }
                   11022:   
1.197     brouard  11023:     /* If line starts with a # it is a comment */
1.277     brouard  11024:     if (line[noffset] == '#') {
1.197     brouard  11025:       numlinepar++;
                   11026:       fputs(line,stdout);
                   11027:       fputs(line,ficparo);
1.278     brouard  11028:       fputs(line,ficres);
1.197     brouard  11029:       fputs(line,ficlog);
                   11030:       continue;
                   11031:     }else
                   11032:       break;
                   11033:   }
                   11034:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11035:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11036:     if (num_filled != 5) {
                   11037:       printf("Should be 5 parameters\n");
1.283     brouard  11038:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11039:     }
1.126     brouard  11040:     numlinepar++;
1.197     brouard  11041:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11042:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11043:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11044:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11045:   }
                   11046:   /* Second parameter line */
                   11047:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11048:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11049:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11050:     if (line[0] == '#') {
                   11051:       numlinepar++;
1.283     brouard  11052:       printf("%s",line);
                   11053:       fprintf(ficres,"%s",line);
                   11054:       fprintf(ficparo,"%s",line);
                   11055:       fprintf(ficlog,"%s",line);
1.197     brouard  11056:       continue;
                   11057:     }else
                   11058:       break;
                   11059:   }
1.223     brouard  11060:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11061:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11062:     if (num_filled != 11) {
                   11063:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11064:       printf("but line=%s\n",line);
1.283     brouard  11065:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11066:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11067:     }
1.286     brouard  11068:     if( lastpass > maxwav){
                   11069:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11070:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11071:       fflush(ficlog);
                   11072:       goto end;
                   11073:     }
                   11074:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11075:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11076:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11077:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11078:   }
1.203     brouard  11079:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11080:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11081:   /* Third parameter line */
                   11082:   while(fgets(line, MAXLINE, ficpar)) {
                   11083:     /* If line starts with a # it is a comment */
                   11084:     if (line[0] == '#') {
                   11085:       numlinepar++;
1.283     brouard  11086:       printf("%s",line);
                   11087:       fprintf(ficres,"%s",line);
                   11088:       fprintf(ficparo,"%s",line);
                   11089:       fprintf(ficlog,"%s",line);
1.197     brouard  11090:       continue;
                   11091:     }else
                   11092:       break;
                   11093:   }
1.201     brouard  11094:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11095:     if (num_filled != 1){
                   11096:       printf("ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
                   11097:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
1.197     brouard  11098:       model[0]='\0';
                   11099:       goto end;
                   11100:     }
                   11101:     else{
                   11102:       if (model[0]=='+'){
                   11103:        for(i=1; i<=strlen(model);i++)
                   11104:          modeltemp[i-1]=model[i];
1.201     brouard  11105:        strcpy(model,modeltemp); 
1.197     brouard  11106:       }
                   11107:     }
1.199     brouard  11108:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11109:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11110:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11111:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11112:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11113:   }
                   11114:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11115:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11116:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11117:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11118:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11119:   fflush(ficlog);
1.190     brouard  11120:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11121:   if(model[0]=='#'){
1.279     brouard  11122:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11123:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11124:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11125:     if(mle != -1){
1.279     brouard  11126:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11127:       exit(1);
                   11128:     }
                   11129:   }
1.126     brouard  11130:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11131:     ungetc(c,ficpar);
                   11132:     fgets(line, MAXLINE, ficpar);
                   11133:     numlinepar++;
1.195     brouard  11134:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11135:       z[0]=line[1];
                   11136:     }
                   11137:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11138:     fputs(line, stdout);
                   11139:     //puts(line);
1.126     brouard  11140:     fputs(line,ficparo);
                   11141:     fputs(line,ficlog);
                   11142:   }
                   11143:   ungetc(c,ficpar);
                   11144: 
                   11145:    
1.290     brouard  11146:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11147:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11148:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11149:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11150:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11151:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11152:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11153:   */
                   11154:   if (strlen(model)>1) 
1.187     brouard  11155:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11156:   else
1.187     brouard  11157:     ncovmodel=2; /* Constant and age */
1.133     brouard  11158:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11159:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11160:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11161:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11162:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11163:     fflush(stdout);
                   11164:     fclose (ficlog);
                   11165:     goto end;
                   11166:   }
1.126     brouard  11167:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11168:   delti=delti3[1][1];
                   11169:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11170:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11171: /* We could also provide initial parameters values giving by simple logistic regression 
                   11172:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11173:       /* for(i=1;i<nlstate;i++){ */
                   11174:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11175:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11176:       /* } */
1.126     brouard  11177:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11178:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11179:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11180:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11181:     fclose (ficparo);
                   11182:     fclose (ficlog);
                   11183:     goto end;
                   11184:     exit(0);
1.220     brouard  11185:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11186:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11187:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11188:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11189:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11190:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11191:     hess=matrix(1,npar,1,npar);
1.220     brouard  11192:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11193:     /* Read guessed parameters */
1.126     brouard  11194:     /* Reads comments: lines beginning with '#' */
                   11195:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11196:       ungetc(c,ficpar);
                   11197:       fgets(line, MAXLINE, ficpar);
                   11198:       numlinepar++;
1.141     brouard  11199:       fputs(line,stdout);
1.126     brouard  11200:       fputs(line,ficparo);
                   11201:       fputs(line,ficlog);
                   11202:     }
                   11203:     ungetc(c,ficpar);
                   11204:     
                   11205:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11206:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11207:     for(i=1; i <=nlstate; i++){
1.234     brouard  11208:       j=0;
1.126     brouard  11209:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11210:        if(jj==i) continue;
                   11211:        j++;
1.292   ! brouard  11212:        while((c=getc(ficpar))=='#' && c!= EOF){
        !          11213:          ungetc(c,ficpar);
        !          11214:          fgets(line, MAXLINE, ficpar);
        !          11215:          numlinepar++;
        !          11216:          fputs(line,stdout);
        !          11217:          fputs(line,ficparo);
        !          11218:          fputs(line,ficlog);
        !          11219:        }
        !          11220:        ungetc(c,ficpar);
1.234     brouard  11221:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11222:        if ((i1 != i) || (j1 != jj)){
                   11223:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11224: It might be a problem of design; if ncovcol and the model are correct\n \
                   11225: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11226:          exit(1);
                   11227:        }
                   11228:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11229:        if(mle==1)
                   11230:          printf("%1d%1d",i,jj);
                   11231:        fprintf(ficlog,"%1d%1d",i,jj);
                   11232:        for(k=1; k<=ncovmodel;k++){
                   11233:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11234:          if(mle==1){
                   11235:            printf(" %lf",param[i][j][k]);
                   11236:            fprintf(ficlog," %lf",param[i][j][k]);
                   11237:          }
                   11238:          else
                   11239:            fprintf(ficlog," %lf",param[i][j][k]);
                   11240:          fprintf(ficparo," %lf",param[i][j][k]);
                   11241:        }
                   11242:        fscanf(ficpar,"\n");
                   11243:        numlinepar++;
                   11244:        if(mle==1)
                   11245:          printf("\n");
                   11246:        fprintf(ficlog,"\n");
                   11247:        fprintf(ficparo,"\n");
1.126     brouard  11248:       }
                   11249:     }  
                   11250:     fflush(ficlog);
1.234     brouard  11251:     
1.251     brouard  11252:     /* Reads parameters values */
1.126     brouard  11253:     p=param[1][1];
1.251     brouard  11254:     pstart=paramstart[1][1];
1.126     brouard  11255:     
                   11256:     /* Reads comments: lines beginning with '#' */
                   11257:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11258:       ungetc(c,ficpar);
                   11259:       fgets(line, MAXLINE, ficpar);
                   11260:       numlinepar++;
1.141     brouard  11261:       fputs(line,stdout);
1.126     brouard  11262:       fputs(line,ficparo);
                   11263:       fputs(line,ficlog);
                   11264:     }
                   11265:     ungetc(c,ficpar);
                   11266: 
                   11267:     for(i=1; i <=nlstate; i++){
                   11268:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11269:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11270:        if ( (i1-i) * (j1-j) != 0){
                   11271:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11272:          exit(1);
                   11273:        }
                   11274:        printf("%1d%1d",i,j);
                   11275:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11276:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11277:        for(k=1; k<=ncovmodel;k++){
                   11278:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11279:          printf(" %le",delti3[i][j][k]);
                   11280:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11281:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11282:        }
                   11283:        fscanf(ficpar,"\n");
                   11284:        numlinepar++;
                   11285:        printf("\n");
                   11286:        fprintf(ficparo,"\n");
                   11287:        fprintf(ficlog,"\n");
1.126     brouard  11288:       }
                   11289:     }
                   11290:     fflush(ficlog);
1.234     brouard  11291:     
1.145     brouard  11292:     /* Reads covariance matrix */
1.126     brouard  11293:     delti=delti3[1][1];
1.220     brouard  11294:                
                   11295:                
1.126     brouard  11296:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11297:                
1.126     brouard  11298:     /* Reads comments: lines beginning with '#' */
                   11299:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11300:       ungetc(c,ficpar);
                   11301:       fgets(line, MAXLINE, ficpar);
                   11302:       numlinepar++;
1.141     brouard  11303:       fputs(line,stdout);
1.126     brouard  11304:       fputs(line,ficparo);
                   11305:       fputs(line,ficlog);
                   11306:     }
                   11307:     ungetc(c,ficpar);
1.220     brouard  11308:                
1.126     brouard  11309:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11310:     hess=matrix(1,npar,1,npar);
1.131     brouard  11311:     for(i=1; i <=npar; i++)
                   11312:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11313:                
1.194     brouard  11314:     /* Scans npar lines */
1.126     brouard  11315:     for(i=1; i <=npar; i++){
1.226     brouard  11316:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11317:       if(count != 3){
1.226     brouard  11318:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11319: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11320: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11321:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11322: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11323: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11324:        exit(1);
1.220     brouard  11325:       }else{
1.226     brouard  11326:        if(mle==1)
                   11327:          printf("%1d%1d%d",i1,j1,jk);
                   11328:       }
                   11329:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11330:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11331:       for(j=1; j <=i; j++){
1.226     brouard  11332:        fscanf(ficpar," %le",&matcov[i][j]);
                   11333:        if(mle==1){
                   11334:          printf(" %.5le",matcov[i][j]);
                   11335:        }
                   11336:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11337:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11338:       }
                   11339:       fscanf(ficpar,"\n");
                   11340:       numlinepar++;
                   11341:       if(mle==1)
1.220     brouard  11342:                                printf("\n");
1.126     brouard  11343:       fprintf(ficlog,"\n");
                   11344:       fprintf(ficparo,"\n");
                   11345:     }
1.194     brouard  11346:     /* End of read covariance matrix npar lines */
1.126     brouard  11347:     for(i=1; i <=npar; i++)
                   11348:       for(j=i+1;j<=npar;j++)
1.226     brouard  11349:        matcov[i][j]=matcov[j][i];
1.126     brouard  11350:     
                   11351:     if(mle==1)
                   11352:       printf("\n");
                   11353:     fprintf(ficlog,"\n");
                   11354:     
                   11355:     fflush(ficlog);
                   11356:     
                   11357:   }    /* End of mle != -3 */
1.218     brouard  11358:   
1.186     brouard  11359:   /*  Main data
                   11360:    */
1.290     brouard  11361:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11362:   /* num=lvector(1,n); */
                   11363:   /* moisnais=vector(1,n); */
                   11364:   /* annais=vector(1,n); */
                   11365:   /* moisdc=vector(1,n); */
                   11366:   /* andc=vector(1,n); */
                   11367:   /* weight=vector(1,n); */
                   11368:   /* agedc=vector(1,n); */
                   11369:   /* cod=ivector(1,n); */
                   11370:   /* for(i=1;i<=n;i++){ */
                   11371:   num=lvector(firstobs,lastobs);
                   11372:   moisnais=vector(firstobs,lastobs);
                   11373:   annais=vector(firstobs,lastobs);
                   11374:   moisdc=vector(firstobs,lastobs);
                   11375:   andc=vector(firstobs,lastobs);
                   11376:   weight=vector(firstobs,lastobs);
                   11377:   agedc=vector(firstobs,lastobs);
                   11378:   cod=ivector(firstobs,lastobs);
                   11379:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11380:     num[i]=0;
                   11381:     moisnais[i]=0;
                   11382:     annais[i]=0;
                   11383:     moisdc[i]=0;
                   11384:     andc[i]=0;
                   11385:     agedc[i]=0;
                   11386:     cod[i]=0;
                   11387:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11388:   }
1.290     brouard  11389:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11390:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11391:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11392:   tab=ivector(1,NCOVMAX);
1.144     brouard  11393:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11394:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11395: 
1.136     brouard  11396:   /* Reads data from file datafile */
                   11397:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11398:     goto end;
                   11399: 
                   11400:   /* Calculation of the number of parameters from char model */
1.234     brouard  11401:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11402:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11403:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11404:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11405:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11406:   */
                   11407:   
                   11408:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11409:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11410:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11411:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11412:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11413:   TvarF=ivector(1,NCOVMAX); /*  */
                   11414:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11415:   TvarV=ivector(1,NCOVMAX); /*  */
                   11416:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11417:   TvarA=ivector(1,NCOVMAX); /*  */
                   11418:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11419:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11420:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11421:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11422:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11423:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11424:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11425:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11426:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11427: 
1.230     brouard  11428:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11429:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11430:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11431:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11432:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11433:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11434:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11435:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11436:   */
                   11437:   /* For model-covariate k tells which data-covariate to use but
                   11438:     because this model-covariate is a construction we invent a new column
                   11439:     ncovcol + k1
                   11440:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11441:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11442:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11443:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11444:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11445:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11446:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11447:   */
1.145     brouard  11448:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11449:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11450:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11451:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11452:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11453:                         4 covariates (3 plus signs)
                   11454:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11455:                      */  
1.230     brouard  11456:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11457:                                * individual dummy, fixed or varying:
                   11458:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11459:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11460:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11461:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11462:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11463:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11464:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11465:                                * individual quantitative, fixed or varying:
                   11466:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11467:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11468:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11469: /* Main decodemodel */
                   11470: 
1.187     brouard  11471: 
1.223     brouard  11472:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11473:     goto end;
                   11474: 
1.137     brouard  11475:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11476:     nbwarn++;
                   11477:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11478:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11479:   }
1.136     brouard  11480:     /*  if(mle==1){*/
1.137     brouard  11481:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11482:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11483:   }
                   11484: 
                   11485:     /*-calculation of age at interview from date of interview and age at death -*/
                   11486:   agev=matrix(1,maxwav,1,imx);
                   11487: 
                   11488:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11489:     goto end;
                   11490: 
1.126     brouard  11491: 
1.136     brouard  11492:   agegomp=(int)agemin;
1.290     brouard  11493:   free_vector(moisnais,firstobs,lastobs);
                   11494:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11495:   /* free_matrix(mint,1,maxwav,1,n);
                   11496:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11497:   /* free_vector(moisdc,1,n); */
                   11498:   /* free_vector(andc,1,n); */
1.145     brouard  11499:   /* */
                   11500:   
1.126     brouard  11501:   wav=ivector(1,imx);
1.214     brouard  11502:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11503:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11504:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11505:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11506:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11507:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11508:    
                   11509:   /* Concatenates waves */
1.214     brouard  11510:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11511:      Death is a valid wave (if date is known).
                   11512:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11513:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11514:      and mw[mi+1][i]. dh depends on stepm.
                   11515:   */
                   11516: 
1.126     brouard  11517:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11518:   /* Concatenates waves */
1.145     brouard  11519:  
1.290     brouard  11520:   free_vector(moisdc,firstobs,lastobs);
                   11521:   free_vector(andc,firstobs,lastobs);
1.215     brouard  11522: 
1.126     brouard  11523:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11524:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11525:   ncodemax[1]=1;
1.145     brouard  11526:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11527:   cptcoveff=0;
1.220     brouard  11528:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11529:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11530:   }
                   11531:   
                   11532:   ncovcombmax=pow(2,cptcoveff);
                   11533:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11534:   for(i=1;i<ncovcombmax;i++)
                   11535:     invalidvarcomb[i]=0;
                   11536:   
1.211     brouard  11537:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11538:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11539:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11540:   
1.200     brouard  11541:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11542:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11543:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11544:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11545:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11546:    * (currently 0 or 1) in the data.
                   11547:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11548:    * corresponding modality (h,j).
                   11549:    */
                   11550: 
1.145     brouard  11551:   h=0;
                   11552:   /*if (cptcovn > 0) */
1.126     brouard  11553:   m=pow(2,cptcoveff);
                   11554:  
1.144     brouard  11555:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11556:           * For k=4 covariates, h goes from 1 to m=2**k
                   11557:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11558:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11559:           *     h\k   1     2     3     4
1.143     brouard  11560:           *______________________________  
                   11561:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11562:           *     2     2     1     1     1
                   11563:           *     3 i=2 1     2     1     1
                   11564:           *     4     2     2     1     1
                   11565:           *     5 i=3 1 i=2 1     2     1
                   11566:           *     6     2     1     2     1
                   11567:           *     7 i=4 1     2     2     1
                   11568:           *     8     2     2     2     1
1.197     brouard  11569:           *     9 i=5 1 i=3 1 i=2 1     2
                   11570:           *    10     2     1     1     2
                   11571:           *    11 i=6 1     2     1     2
                   11572:           *    12     2     2     1     2
                   11573:           *    13 i=7 1 i=4 1     2     2    
                   11574:           *    14     2     1     2     2
                   11575:           *    15 i=8 1     2     2     2
                   11576:           *    16     2     2     2     2
1.143     brouard  11577:           */
1.212     brouard  11578:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11579:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11580:      * and the value of each covariate?
                   11581:      * V1=1, V2=1, V3=2, V4=1 ?
                   11582:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11583:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11584:      * In order to get the real value in the data, we use nbcode
                   11585:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11586:      * We are keeping this crazy system in order to be able (in the future?) 
                   11587:      * to have more than 2 values (0 or 1) for a covariate.
                   11588:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11589:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11590:      *              bbbbbbbb
                   11591:      *              76543210     
                   11592:      *   h-1        00000101 (6-1=5)
1.219     brouard  11593:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11594:      *           &
                   11595:      *     1        00000001 (1)
1.219     brouard  11596:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11597:      *          +1= 00000001 =1 
1.211     brouard  11598:      *
                   11599:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11600:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11601:      *    >>k'            11
                   11602:      *          &   00000001
                   11603:      *            = 00000001
                   11604:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11605:      * Reverse h=6 and m=16?
                   11606:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11607:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11608:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11609:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11610:      * V3=decodtabm(14,3,2**4)=2
                   11611:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11612:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11613:      *          &1 000000001
                   11614:      *           = 000000001
                   11615:      *         +1= 000000010 =2
                   11616:      *                  2211
                   11617:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11618:      *                  V3=2
1.220     brouard  11619:                 * codtabm and decodtabm are identical
1.211     brouard  11620:      */
                   11621: 
1.145     brouard  11622: 
                   11623:  free_ivector(Ndum,-1,NCOVMAX);
                   11624: 
                   11625: 
1.126     brouard  11626:     
1.186     brouard  11627:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11628:   strcpy(optionfilegnuplot,optionfilefiname);
                   11629:   if(mle==-3)
1.201     brouard  11630:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11631:   strcat(optionfilegnuplot,".gp");
                   11632: 
                   11633:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11634:     printf("Problem with file %s",optionfilegnuplot);
                   11635:   }
                   11636:   else{
1.204     brouard  11637:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11638:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11639:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11640:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11641:   }
                   11642:   /*  fclose(ficgp);*/
1.186     brouard  11643: 
                   11644: 
                   11645:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11646: 
                   11647:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11648:   if(mle==-3)
1.201     brouard  11649:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11650:   strcat(optionfilehtm,".htm");
                   11651:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11652:     printf("Problem with %s \n",optionfilehtm);
                   11653:     exit(0);
1.126     brouard  11654:   }
                   11655: 
                   11656:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11657:   strcat(optionfilehtmcov,"-cov.htm");
                   11658:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11659:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11660:   }
                   11661:   else{
                   11662:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11663: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11664: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11665:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11666:   }
                   11667: 
1.213     brouard  11668:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11669: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11670: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11671: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11672: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11673: \n\
                   11674: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11675:  <ul><li><h4>Parameter files</h4>\n\
                   11676:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11677:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11678:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11679:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11680:  - Date and time at start: %s</ul>\n",\
                   11681:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11682:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11683:          fileres,fileres,\
                   11684:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11685:   fflush(fichtm);
                   11686: 
                   11687:   strcpy(pathr,path);
                   11688:   strcat(pathr,optionfilefiname);
1.184     brouard  11689: #ifdef WIN32
                   11690:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11691: #else
1.126     brouard  11692:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11693: #endif
                   11694:          
1.126     brouard  11695:   
1.220     brouard  11696:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11697:                 and for any valid combination of covariates
1.126     brouard  11698:      and prints on file fileres'p'. */
1.251     brouard  11699:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11700:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11701: 
                   11702:   fprintf(fichtm,"\n");
1.286     brouard  11703:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11704:          ftol, stepm);
                   11705:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11706:   ncurrv=1;
                   11707:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11708:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11709:   ncurrv=i;
                   11710:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11711:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  11712:   ncurrv=i;
                   11713:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11714:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  11715:   ncurrv=i;
                   11716:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11717:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11718:           nlstate, ndeath, maxwav, mle, weightopt);
                   11719: 
                   11720:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11721: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11722: 
                   11723:   
                   11724:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11725: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11726: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11727:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11728:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11729:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11730:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11731:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11732:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11733: 
1.126     brouard  11734:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11735:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11736:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11737: 
                   11738:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11739:   /* For mortality only */
1.126     brouard  11740:   if (mle==-3){
1.136     brouard  11741:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11742:     for(i=1;i<=NDIM;i++)
                   11743:       for(j=1;j<=NDIM;j++)
                   11744:        ximort[i][j]=0.;
1.186     brouard  11745:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  11746:     cens=ivector(firstobs,lastobs);
                   11747:     ageexmed=vector(firstobs,lastobs);
                   11748:     agecens=vector(firstobs,lastobs);
                   11749:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  11750:                
1.126     brouard  11751:     for (i=1; i<=imx; i++){
                   11752:       dcwave[i]=-1;
                   11753:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11754:        if (s[m][i]>nlstate) {
                   11755:          dcwave[i]=m;
                   11756:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11757:          break;
                   11758:        }
1.126     brouard  11759:     }
1.226     brouard  11760:     
1.126     brouard  11761:     for (i=1; i<=imx; i++) {
                   11762:       if (wav[i]>0){
1.226     brouard  11763:        ageexmed[i]=agev[mw[1][i]][i];
                   11764:        j=wav[i];
                   11765:        agecens[i]=1.; 
                   11766:        
                   11767:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11768:          agecens[i]=agev[mw[j][i]][i];
                   11769:          cens[i]= 1;
                   11770:        }else if (ageexmed[i]< 1) 
                   11771:          cens[i]= -1;
                   11772:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11773:          cens[i]=0 ;
1.126     brouard  11774:       }
                   11775:       else cens[i]=-1;
                   11776:     }
                   11777:     
                   11778:     for (i=1;i<=NDIM;i++) {
                   11779:       for (j=1;j<=NDIM;j++)
1.226     brouard  11780:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11781:     }
                   11782:     
1.145     brouard  11783:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11784:     /*printf("%lf %lf", p[1], p[2]);*/
                   11785:     
                   11786:     
1.136     brouard  11787: #ifdef GSL
                   11788:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11789: #else
1.126     brouard  11790:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11791: #endif
1.201     brouard  11792:     strcpy(filerespow,"POW-MORT_"); 
                   11793:     strcat(filerespow,fileresu);
1.126     brouard  11794:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11795:       printf("Problem with resultfile: %s\n", filerespow);
                   11796:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11797:     }
1.136     brouard  11798: #ifdef GSL
                   11799:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11800: #else
1.126     brouard  11801:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11802: #endif
1.126     brouard  11803:     /*  for (i=1;i<=nlstate;i++)
                   11804:        for(j=1;j<=nlstate+ndeath;j++)
                   11805:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11806:     */
                   11807:     fprintf(ficrespow,"\n");
1.136     brouard  11808: #ifdef GSL
                   11809:     /* gsl starts here */ 
                   11810:     T = gsl_multimin_fminimizer_nmsimplex;
                   11811:     gsl_multimin_fminimizer *sfm = NULL;
                   11812:     gsl_vector *ss, *x;
                   11813:     gsl_multimin_function minex_func;
                   11814: 
                   11815:     /* Initial vertex size vector */
                   11816:     ss = gsl_vector_alloc (NDIM);
                   11817:     
                   11818:     if (ss == NULL){
                   11819:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11820:     }
                   11821:     /* Set all step sizes to 1 */
                   11822:     gsl_vector_set_all (ss, 0.001);
                   11823: 
                   11824:     /* Starting point */
1.126     brouard  11825:     
1.136     brouard  11826:     x = gsl_vector_alloc (NDIM);
                   11827:     
                   11828:     if (x == NULL){
                   11829:       gsl_vector_free(ss);
                   11830:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11831:     }
                   11832:   
                   11833:     /* Initialize method and iterate */
                   11834:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11835:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11836:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11837:     gsl_vector_set(x, 0, p[1]);
                   11838:     gsl_vector_set(x, 1, p[2]);
                   11839: 
                   11840:     minex_func.f = &gompertz_f;
                   11841:     minex_func.n = NDIM;
                   11842:     minex_func.params = (void *)&p; /* ??? */
                   11843:     
                   11844:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11845:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11846:     
                   11847:     printf("Iterations beginning .....\n\n");
                   11848:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11849: 
                   11850:     iteri=0;
                   11851:     while (rval == GSL_CONTINUE){
                   11852:       iteri++;
                   11853:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11854:       
                   11855:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11856:       fflush(0);
                   11857:       
                   11858:       if (status) 
                   11859:         break;
                   11860:       
                   11861:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11862:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11863:       
                   11864:       if (rval == GSL_SUCCESS)
                   11865:         printf ("converged to a local maximum at\n");
                   11866:       
                   11867:       printf("%5d ", iteri);
                   11868:       for (it = 0; it < NDIM; it++){
                   11869:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11870:       }
                   11871:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11872:     }
                   11873:     
                   11874:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11875:     
                   11876:     gsl_vector_free(x); /* initial values */
                   11877:     gsl_vector_free(ss); /* inital step size */
                   11878:     for (it=0; it<NDIM; it++){
                   11879:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11880:       fprintf(ficrespow," %.12lf", p[it]);
                   11881:     }
                   11882:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11883: #endif
                   11884: #ifdef POWELL
                   11885:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11886: #endif  
1.126     brouard  11887:     fclose(ficrespow);
                   11888:     
1.203     brouard  11889:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11890: 
                   11891:     for(i=1; i <=NDIM; i++)
                   11892:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11893:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11894:     
                   11895:     printf("\nCovariance matrix\n ");
1.203     brouard  11896:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11897:     for(i=1; i <=NDIM; i++) {
                   11898:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11899:                                printf("%f ",matcov[i][j]);
                   11900:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11901:       }
1.203     brouard  11902:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11903:     }
                   11904:     
                   11905:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11906:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11907:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11908:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11909:     }
1.126     brouard  11910:     lsurv=vector(1,AGESUP);
                   11911:     lpop=vector(1,AGESUP);
                   11912:     tpop=vector(1,AGESUP);
                   11913:     lsurv[agegomp]=100000;
                   11914:     
                   11915:     for (k=agegomp;k<=AGESUP;k++) {
                   11916:       agemortsup=k;
                   11917:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11918:     }
                   11919:     
                   11920:     for (k=agegomp;k<agemortsup;k++)
                   11921:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11922:     
                   11923:     for (k=agegomp;k<agemortsup;k++){
                   11924:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11925:       sumlpop=sumlpop+lpop[k];
                   11926:     }
                   11927:     
                   11928:     tpop[agegomp]=sumlpop;
                   11929:     for (k=agegomp;k<(agemortsup-3);k++){
                   11930:       /*  tpop[k+1]=2;*/
                   11931:       tpop[k+1]=tpop[k]-lpop[k];
                   11932:     }
                   11933:     
                   11934:     
                   11935:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11936:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11937:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11938:     
                   11939:     
                   11940:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11941:                ageminpar=50;
                   11942:                agemaxpar=100;
1.194     brouard  11943:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11944:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11945: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11946: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11947:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11948: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11949: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11950:     }else{
                   11951:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11952:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11953:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11954:                }
1.201     brouard  11955:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11956:                     stepm, weightopt,\
                   11957:                     model,imx,p,matcov,agemortsup);
                   11958:     
                   11959:     free_vector(lsurv,1,AGESUP);
                   11960:     free_vector(lpop,1,AGESUP);
                   11961:     free_vector(tpop,1,AGESUP);
1.220     brouard  11962:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  11963:     free_ivector(dcwave,firstobs,lastobs);
                   11964:     free_vector(agecens,firstobs,lastobs);
                   11965:     free_vector(ageexmed,firstobs,lastobs);
                   11966:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  11967: #ifdef GSL
1.136     brouard  11968: #endif
1.186     brouard  11969:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11970:   /* Standard  */
                   11971:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11972:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11973:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11974:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11975:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11976:     for (k=1; k<=npar;k++)
                   11977:       printf(" %d %8.5f",k,p[k]);
                   11978:     printf("\n");
1.205     brouard  11979:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11980:       /* mlikeli uses func not funcone */
1.247     brouard  11981:       /* for(i=1;i<nlstate;i++){ */
                   11982:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11983:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11984:       /* } */
1.205     brouard  11985:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11986:     }
                   11987:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11988:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11989:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11990:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11991:     }
                   11992:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  11993:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   11994:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11995:     for (k=1; k<=npar;k++)
                   11996:       printf(" %d %8.5f",k,p[k]);
                   11997:     printf("\n");
                   11998:     
                   11999:     /*--------- results files --------------*/
1.283     brouard  12000:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12001:     
                   12002:     
                   12003:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12004:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12005:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12006:     for(i=1,jk=1; i <=nlstate; i++){
                   12007:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12008:        if (k != i) {
                   12009:          printf("%d%d ",i,k);
                   12010:          fprintf(ficlog,"%d%d ",i,k);
                   12011:          fprintf(ficres,"%1d%1d ",i,k);
                   12012:          for(j=1; j <=ncovmodel; j++){
                   12013:            printf("%12.7f ",p[jk]);
                   12014:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12015:            fprintf(ficres,"%12.7f ",p[jk]);
                   12016:            jk++; 
                   12017:          }
                   12018:          printf("\n");
                   12019:          fprintf(ficlog,"\n");
                   12020:          fprintf(ficres,"\n");
                   12021:        }
1.126     brouard  12022:       }
                   12023:     }
1.203     brouard  12024:     if(mle != 0){
                   12025:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12026:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12027:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12028:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12029:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12030:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12031:        for(k=1; k <=(nlstate+ndeath); k++){
                   12032:          if (k != i) {
                   12033:            printf("%d%d ",i,k);
                   12034:            fprintf(ficlog,"%d%d ",i,k);
                   12035:            for(j=1; j <=ncovmodel; j++){
                   12036:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12037:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12038:              jk++; 
                   12039:            }
                   12040:            printf("\n");
                   12041:            fprintf(ficlog,"\n");
                   12042:          }
                   12043:        }
1.193     brouard  12044:       }
1.203     brouard  12045:     } /* end of hesscov and Wald tests */
1.225     brouard  12046:     
1.203     brouard  12047:     /*  */
1.126     brouard  12048:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12049:     printf("# Scales (for hessian or gradient estimation)\n");
                   12050:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12051:     for(i=1,jk=1; i <=nlstate; i++){
                   12052:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12053:        if (j!=i) {
                   12054:          fprintf(ficres,"%1d%1d",i,j);
                   12055:          printf("%1d%1d",i,j);
                   12056:          fprintf(ficlog,"%1d%1d",i,j);
                   12057:          for(k=1; k<=ncovmodel;k++){
                   12058:            printf(" %.5e",delti[jk]);
                   12059:            fprintf(ficlog," %.5e",delti[jk]);
                   12060:            fprintf(ficres," %.5e",delti[jk]);
                   12061:            jk++;
                   12062:          }
                   12063:          printf("\n");
                   12064:          fprintf(ficlog,"\n");
                   12065:          fprintf(ficres,"\n");
                   12066:        }
1.126     brouard  12067:       }
                   12068:     }
                   12069:     
                   12070:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12071:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12072:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12073:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12074:     /* # 121 Var(a12)\n\ */
                   12075:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12076:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12077:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12078:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12079:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12080:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12081:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12082:     
                   12083:     
                   12084:     /* Just to have a covariance matrix which will be more understandable
                   12085:        even is we still don't want to manage dictionary of variables
                   12086:     */
                   12087:     for(itimes=1;itimes<=2;itimes++){
                   12088:       jj=0;
                   12089:       for(i=1; i <=nlstate; i++){
1.225     brouard  12090:        for(j=1; j <=nlstate+ndeath; j++){
                   12091:          if(j==i) continue;
                   12092:          for(k=1; k<=ncovmodel;k++){
                   12093:            jj++;
                   12094:            ca[0]= k+'a'-1;ca[1]='\0';
                   12095:            if(itimes==1){
                   12096:              if(mle>=1)
                   12097:                printf("#%1d%1d%d",i,j,k);
                   12098:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12099:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12100:            }else{
                   12101:              if(mle>=1)
                   12102:                printf("%1d%1d%d",i,j,k);
                   12103:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12104:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12105:            }
                   12106:            ll=0;
                   12107:            for(li=1;li <=nlstate; li++){
                   12108:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12109:                if(lj==li) continue;
                   12110:                for(lk=1;lk<=ncovmodel;lk++){
                   12111:                  ll++;
                   12112:                  if(ll<=jj){
                   12113:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12114:                    if(ll<jj){
                   12115:                      if(itimes==1){
                   12116:                        if(mle>=1)
                   12117:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12118:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12119:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12120:                      }else{
                   12121:                        if(mle>=1)
                   12122:                          printf(" %.5e",matcov[jj][ll]); 
                   12123:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12124:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12125:                      }
                   12126:                    }else{
                   12127:                      if(itimes==1){
                   12128:                        if(mle>=1)
                   12129:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12130:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12131:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12132:                      }else{
                   12133:                        if(mle>=1)
                   12134:                          printf(" %.7e",matcov[jj][ll]); 
                   12135:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12136:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12137:                      }
                   12138:                    }
                   12139:                  }
                   12140:                } /* end lk */
                   12141:              } /* end lj */
                   12142:            } /* end li */
                   12143:            if(mle>=1)
                   12144:              printf("\n");
                   12145:            fprintf(ficlog,"\n");
                   12146:            fprintf(ficres,"\n");
                   12147:            numlinepar++;
                   12148:          } /* end k*/
                   12149:        } /*end j */
1.126     brouard  12150:       } /* end i */
                   12151:     } /* end itimes */
                   12152:     
                   12153:     fflush(ficlog);
                   12154:     fflush(ficres);
1.225     brouard  12155:     while(fgets(line, MAXLINE, ficpar)) {
                   12156:       /* If line starts with a # it is a comment */
                   12157:       if (line[0] == '#') {
                   12158:        numlinepar++;
                   12159:        fputs(line,stdout);
                   12160:        fputs(line,ficparo);
                   12161:        fputs(line,ficlog);
                   12162:        continue;
                   12163:       }else
                   12164:        break;
                   12165:     }
                   12166:     
1.209     brouard  12167:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12168:     /*   ungetc(c,ficpar); */
                   12169:     /*   fgets(line, MAXLINE, ficpar); */
                   12170:     /*   fputs(line,stdout); */
                   12171:     /*   fputs(line,ficparo); */
                   12172:     /* } */
                   12173:     /* ungetc(c,ficpar); */
1.126     brouard  12174:     
                   12175:     estepm=0;
1.209     brouard  12176:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12177:       
                   12178:       if (num_filled != 6) {
                   12179:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12180:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12181:        goto end;
                   12182:       }
                   12183:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12184:     }
                   12185:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12186:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12187:     
1.209     brouard  12188:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12189:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12190:     if (fage <= 2) {
                   12191:       bage = ageminpar;
                   12192:       fage = agemaxpar;
                   12193:     }
                   12194:     
                   12195:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12196:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12197:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12198:                
1.186     brouard  12199:     /* Other stuffs, more or less useful */    
1.254     brouard  12200:     while(fgets(line, MAXLINE, ficpar)) {
                   12201:       /* If line starts with a # it is a comment */
                   12202:       if (line[0] == '#') {
                   12203:        numlinepar++;
                   12204:        fputs(line,stdout);
                   12205:        fputs(line,ficparo);
                   12206:        fputs(line,ficlog);
                   12207:        continue;
                   12208:       }else
                   12209:        break;
                   12210:     }
                   12211: 
                   12212:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12213:       
                   12214:       if (num_filled != 7) {
                   12215:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12216:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12217:        goto end;
                   12218:       }
                   12219:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12220:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12221:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12222:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12223:     }
1.254     brouard  12224: 
                   12225:     while(fgets(line, MAXLINE, ficpar)) {
                   12226:       /* If line starts with a # it is a comment */
                   12227:       if (line[0] == '#') {
                   12228:        numlinepar++;
                   12229:        fputs(line,stdout);
                   12230:        fputs(line,ficparo);
                   12231:        fputs(line,ficlog);
                   12232:        continue;
                   12233:       }else
                   12234:        break;
1.126     brouard  12235:     }
                   12236:     
                   12237:     
                   12238:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12239:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12240:     
1.254     brouard  12241:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12242:       if (num_filled != 1) {
                   12243:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12244:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12245:        goto end;
                   12246:       }
                   12247:       printf("pop_based=%d\n",popbased);
                   12248:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12249:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12250:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12251:     }
                   12252:      
1.258     brouard  12253:     /* Results */
                   12254:     nresult=0;
                   12255:     do{
                   12256:       if(!fgets(line, MAXLINE, ficpar)){
                   12257:        endishere=1;
                   12258:        parameterline=14;
                   12259:       }else if (line[0] == '#') {
                   12260:        /* If line starts with a # it is a comment */
1.254     brouard  12261:        numlinepar++;
                   12262:        fputs(line,stdout);
                   12263:        fputs(line,ficparo);
                   12264:        fputs(line,ficlog);
                   12265:        continue;
1.258     brouard  12266:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12267:        parameterline=11;
                   12268:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12269:        parameterline=12;
                   12270:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12271:        parameterline=13;
                   12272:       else{
                   12273:        parameterline=14;
1.254     brouard  12274:       }
1.258     brouard  12275:       switch (parameterline){ 
                   12276:       case 11:
                   12277:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12278:          if (num_filled != 8) {
                   12279:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12280:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12281:            goto end;
                   12282:          }
                   12283:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12284:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12285:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12286:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12287:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12288:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12289:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
                   12290: 
1.258     brouard  12291:        }
1.254     brouard  12292:        break;
1.258     brouard  12293:       case 12:
                   12294:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12295:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12296:          if (num_filled != 8) {
1.262     brouard  12297:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12298:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12299:            goto end;
                   12300:          }
                   12301:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12302:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12303:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12304:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12305:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12306:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12307:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.258     brouard  12308:        }
1.230     brouard  12309:        break;
1.258     brouard  12310:       case 13:
                   12311:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12312:          if (num_filled == 0){
                   12313:            resultline[0]='\0';
                   12314:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12315:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12316:            break;
                   12317:          } else if (num_filled != 1){
                   12318:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12319:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12320:          }
                   12321:          nresult++; /* Sum of resultlines */
                   12322:          printf("Result %d: result=%s\n",nresult, resultline);
                   12323:          if(nresult > MAXRESULTLINES){
                   12324:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12325:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12326:            goto end;
                   12327:          }
                   12328:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12329:          fprintf(ficparo,"result: %s\n",resultline);
                   12330:          fprintf(ficres,"result: %s\n",resultline);
                   12331:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12332:          break;
1.258     brouard  12333:        case 14: 
1.259     brouard  12334:          if(ncovmodel >2 && nresult==0 ){
                   12335:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12336:            goto end;
                   12337:          }
1.259     brouard  12338:          break;
1.258     brouard  12339:        default:
                   12340:          nresult=1;
                   12341:          decoderesult(".",nresult ); /* No covariate */
                   12342:        }
                   12343:       } /* End switch parameterline */
                   12344:     }while(endishere==0); /* End do */
1.126     brouard  12345:     
1.230     brouard  12346:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12347:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12348:     
                   12349:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12350:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12351:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12352: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12353: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12354:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12355: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12356: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12357:     }else{
1.270     brouard  12358:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12359:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12360:     }
                   12361:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12362:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.273     brouard  12363:                 jprev1,mprev1,anprev1,dateprev1, dateproj1, dateback1,jprev2,mprev2,anprev2,dateprev2,dateproj2, dateback2);
1.220     brouard  12364:                
1.225     brouard  12365:     /*------------ free_vector  -------------*/
                   12366:     /*  chdir(path); */
1.220     brouard  12367:                
1.215     brouard  12368:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12369:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12370:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12371:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12372:     free_lvector(num,firstobs,lastobs);
                   12373:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12374:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12375:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12376:     fclose(ficparo);
                   12377:     fclose(ficres);
1.220     brouard  12378:                
                   12379:                
1.186     brouard  12380:     /* Other results (useful)*/
1.220     brouard  12381:                
                   12382:                
1.126     brouard  12383:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12384:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12385:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12386:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12387:     fclose(ficrespl);
                   12388: 
                   12389:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12390:     /*#include "hpijx.h"*/
                   12391:     hPijx(p, bage, fage);
1.145     brouard  12392:     fclose(ficrespij);
1.227     brouard  12393:     
1.220     brouard  12394:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12395:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12396:     k=1;
1.126     brouard  12397:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12398:     
1.269     brouard  12399:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12400:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12401:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12402:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12403:        for(k=1;k<=ncovcombmax;k++)
                   12404:          probs[i][j][k]=0.;
1.269     brouard  12405:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12406:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12407:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12408:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12409:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12410:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12411:          for(k=1;k<=ncovcombmax;k++)
                   12412:            mobaverages[i][j][k]=0.;
1.219     brouard  12413:       mobaverage=mobaverages;
                   12414:       if (mobilav!=0) {
1.235     brouard  12415:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12416:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12417:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12418:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12419:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12420:        }
1.269     brouard  12421:       } else if (mobilavproj !=0) {
1.235     brouard  12422:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12423:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12424:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12425:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12426:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12427:        }
1.269     brouard  12428:       }else{
                   12429:        printf("Internal error moving average\n");
                   12430:        fflush(stdout);
                   12431:        exit(1);
1.219     brouard  12432:       }
                   12433:     }/* end if moving average */
1.227     brouard  12434:     
1.126     brouard  12435:     /*---------- Forecasting ------------------*/
                   12436:     if(prevfcast==1){
                   12437:       /*    if(stepm ==1){*/
1.269     brouard  12438:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12439:     }
1.269     brouard  12440: 
                   12441:     /* Backcasting */
1.217     brouard  12442:     if(backcast==1){
1.219     brouard  12443:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12444:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12445:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12446: 
                   12447:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12448: 
                   12449:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12450: 
1.219     brouard  12451:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12452:       fclose(ficresplb);
                   12453: 
1.222     brouard  12454:       hBijx(p, bage, fage, mobaverage);
                   12455:       fclose(ficrespijb);
1.219     brouard  12456: 
1.269     brouard  12457:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12458:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12459:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12460: 
                   12461:       
1.269     brouard  12462:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12463:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12464:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12465:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12466:     }    /* end  Backcasting */
1.268     brouard  12467:  
1.186     brouard  12468:  
                   12469:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12470: 
1.215     brouard  12471:     free_ivector(wav,1,imx);
                   12472:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12473:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12474:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12475:                
                   12476:                
1.127     brouard  12477:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12478:                
1.201     brouard  12479:     strcpy(filerese,"E_");
                   12480:     strcat(filerese,fileresu);
1.126     brouard  12481:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12482:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12483:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12484:     }
1.208     brouard  12485:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12486:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12487: 
                   12488:     pstamp(ficreseij);
1.219     brouard  12489:                
1.235     brouard  12490:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12491:     if (cptcovn < 1){i1=1;}
                   12492:     
                   12493:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12494:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12495:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12496:        continue;
1.219     brouard  12497:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12498:       printf("\n#****** ");
1.225     brouard  12499:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12500:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12501:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12502:       }
                   12503:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12504:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12505:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12506:       }
                   12507:       fprintf(ficreseij,"******\n");
1.235     brouard  12508:       printf("******\n");
1.219     brouard  12509:       
                   12510:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12511:       oldm=oldms;savm=savms;
1.235     brouard  12512:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12513:       
1.219     brouard  12514:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12515:     }
                   12516:     fclose(ficreseij);
1.208     brouard  12517:     printf("done evsij\n");fflush(stdout);
                   12518:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12519: 
1.218     brouard  12520:                
1.227     brouard  12521:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12522:                
1.201     brouard  12523:     strcpy(filerest,"T_");
                   12524:     strcat(filerest,fileresu);
1.127     brouard  12525:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12526:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12527:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12528:     }
1.208     brouard  12529:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12530:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12531:     strcpy(fileresstde,"STDE_");
                   12532:     strcat(fileresstde,fileresu);
1.126     brouard  12533:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12534:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12535:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12536:     }
1.227     brouard  12537:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12538:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12539: 
1.201     brouard  12540:     strcpy(filerescve,"CVE_");
                   12541:     strcat(filerescve,fileresu);
1.126     brouard  12542:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12543:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12544:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12545:     }
1.227     brouard  12546:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12547:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12548: 
1.201     brouard  12549:     strcpy(fileresv,"V_");
                   12550:     strcat(fileresv,fileresu);
1.126     brouard  12551:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12552:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12553:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12554:     }
1.227     brouard  12555:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12556:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12557: 
1.235     brouard  12558:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12559:     if (cptcovn < 1){i1=1;}
                   12560:     
                   12561:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12562:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12563:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12564:        continue;
1.242     brouard  12565:       printf("\n#****** Result for:");
                   12566:       fprintf(ficrest,"\n#****** Result for:");
                   12567:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12568:       for(j=1;j<=cptcoveff;j++){ 
                   12569:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12570:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12571:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12572:       }
1.235     brouard  12573:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12574:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12575:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12576:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12577:       }        
1.208     brouard  12578:       fprintf(ficrest,"******\n");
1.227     brouard  12579:       fprintf(ficlog,"******\n");
                   12580:       printf("******\n");
1.208     brouard  12581:       
                   12582:       fprintf(ficresstdeij,"\n#****** ");
                   12583:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12584:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12585:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12586:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12587:       }
1.235     brouard  12588:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12589:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12590:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12591:       }        
1.208     brouard  12592:       fprintf(ficresstdeij,"******\n");
                   12593:       fprintf(ficrescveij,"******\n");
                   12594:       
                   12595:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12596:       /* pstamp(ficresvij); */
1.225     brouard  12597:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12598:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12599:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12600:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12601:       }        
1.208     brouard  12602:       fprintf(ficresvij,"******\n");
                   12603:       
                   12604:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12605:       oldm=oldms;savm=savms;
1.235     brouard  12606:       printf(" cvevsij ");
                   12607:       fprintf(ficlog, " cvevsij ");
                   12608:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12609:       printf(" end cvevsij \n ");
                   12610:       fprintf(ficlog, " end cvevsij \n ");
                   12611:       
                   12612:       /*
                   12613:        */
                   12614:       /* goto endfree; */
                   12615:       
                   12616:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12617:       pstamp(ficrest);
                   12618:       
1.269     brouard  12619:       epj=vector(1,nlstate+1);
1.208     brouard  12620:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12621:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12622:        cptcod= 0; /* To be deleted */
                   12623:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12624:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12625:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12626:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12627:        if(vpopbased==1)
                   12628:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12629:        else
1.288     brouard  12630:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12631:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12632:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12633:        fprintf(ficrest,"\n");
                   12634:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  12635:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   12636:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12637:        for(age=bage; age <=fage ;age++){
1.235     brouard  12638:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12639:          if (vpopbased==1) {
                   12640:            if(mobilav ==0){
                   12641:              for(i=1; i<=nlstate;i++)
                   12642:                prlim[i][i]=probs[(int)age][i][k];
                   12643:            }else{ /* mobilav */ 
                   12644:              for(i=1; i<=nlstate;i++)
                   12645:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12646:            }
                   12647:          }
1.219     brouard  12648:          
1.227     brouard  12649:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12650:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12651:          /* printf(" age %4.0f ",age); */
                   12652:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12653:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12654:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12655:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12656:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12657:            }
                   12658:            epj[nlstate+1] +=epj[j];
                   12659:          }
                   12660:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12661:          
1.227     brouard  12662:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12663:            for(j=1;j <=nlstate;j++)
                   12664:              vepp += vareij[i][j][(int)age];
                   12665:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12666:          for(j=1;j <=nlstate;j++){
                   12667:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12668:          }
                   12669:          fprintf(ficrest,"\n");
                   12670:        }
1.208     brouard  12671:       } /* End vpopbased */
1.269     brouard  12672:       free_vector(epj,1,nlstate+1);
1.208     brouard  12673:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12674:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12675:       printf("done selection\n");fflush(stdout);
                   12676:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12677:       
1.235     brouard  12678:     } /* End k selection */
1.227     brouard  12679: 
                   12680:     printf("done State-specific expectancies\n");fflush(stdout);
                   12681:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12682: 
1.288     brouard  12683:     /* variance-covariance of forward period prevalence*/
1.269     brouard  12684:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12685: 
1.227     brouard  12686:     
1.290     brouard  12687:     free_vector(weight,firstobs,lastobs);
1.227     brouard  12688:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  12689:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   12690:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   12691:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   12692:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  12693:     free_ivector(tab,1,NCOVMAX);
                   12694:     fclose(ficresstdeij);
                   12695:     fclose(ficrescveij);
                   12696:     fclose(ficresvij);
                   12697:     fclose(ficrest);
                   12698:     fclose(ficpar);
                   12699:     
                   12700:     
1.126     brouard  12701:     /*---------- End : free ----------------*/
1.219     brouard  12702:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12703:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12704:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12705:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12706:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12707:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12708:   /* endfree:*/
                   12709:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12710:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12711:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  12712:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   12713:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   12714:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   12715:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  12716:   free_matrix(matcov,1,npar,1,npar);
                   12717:   free_matrix(hess,1,npar,1,npar);
                   12718:   /*free_vector(delti,1,npar);*/
                   12719:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12720:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12721:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12722:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12723:   
                   12724:   free_ivector(ncodemax,1,NCOVMAX);
                   12725:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12726:   free_ivector(Dummy,-1,NCOVMAX);
                   12727:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12728:   free_ivector(DummyV,1,NCOVMAX);
                   12729:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12730:   free_ivector(Typevar,-1,NCOVMAX);
                   12731:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12732:   free_ivector(TvarsQ,1,NCOVMAX);
                   12733:   free_ivector(TvarsQind,1,NCOVMAX);
                   12734:   free_ivector(TvarsD,1,NCOVMAX);
                   12735:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12736:   free_ivector(TvarFD,1,NCOVMAX);
                   12737:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12738:   free_ivector(TvarF,1,NCOVMAX);
                   12739:   free_ivector(TvarFind,1,NCOVMAX);
                   12740:   free_ivector(TvarV,1,NCOVMAX);
                   12741:   free_ivector(TvarVind,1,NCOVMAX);
                   12742:   free_ivector(TvarA,1,NCOVMAX);
                   12743:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12744:   free_ivector(TvarFQ,1,NCOVMAX);
                   12745:   free_ivector(TvarFQind,1,NCOVMAX);
                   12746:   free_ivector(TvarVD,1,NCOVMAX);
                   12747:   free_ivector(TvarVDind,1,NCOVMAX);
                   12748:   free_ivector(TvarVQ,1,NCOVMAX);
                   12749:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12750:   free_ivector(Tvarsel,1,NCOVMAX);
                   12751:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12752:   free_ivector(Tposprod,1,NCOVMAX);
                   12753:   free_ivector(Tprod,1,NCOVMAX);
                   12754:   free_ivector(Tvaraff,1,NCOVMAX);
                   12755:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12756:   free_ivector(Tage,1,NCOVMAX);
                   12757:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12758:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12759:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12760:   
                   12761:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12762:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12763:   fflush(fichtm);
                   12764:   fflush(ficgp);
                   12765:   
1.227     brouard  12766:   
1.126     brouard  12767:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12768:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12769:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12770:   }else{
                   12771:     printf("End of Imach\n");
                   12772:     fprintf(ficlog,"End of Imach\n");
                   12773:   }
                   12774:   printf("See log file on %s\n",filelog);
                   12775:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12776:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12777:   rend_time = time(NULL);  
                   12778:   end_time = *localtime(&rend_time);
                   12779:   /* tml = *localtime(&end_time.tm_sec); */
                   12780:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12781:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12782:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12783:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12784:   
1.157     brouard  12785:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12786:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12787:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12788:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12789: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12790:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12791:   fclose(fichtm);
                   12792:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12793:   fclose(fichtmcov);
                   12794:   fclose(ficgp);
                   12795:   fclose(ficlog);
                   12796:   /*------ End -----------*/
1.227     brouard  12797:   
1.281     brouard  12798: 
                   12799: /* Executes gnuplot */
1.227     brouard  12800:   
                   12801:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12802: #ifdef WIN32
1.227     brouard  12803:   if (_chdir(pathcd) != 0)
                   12804:     printf("Can't move to directory %s!\n",path);
                   12805:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12806: #else
1.227     brouard  12807:     if(chdir(pathcd) != 0)
                   12808:       printf("Can't move to directory %s!\n", path);
                   12809:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12810: #endif 
1.126     brouard  12811:     printf("Current directory %s!\n",pathcd);
                   12812:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12813:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12814: #ifdef _WIN32
1.126     brouard  12815:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12816: #endif
                   12817:   if(!stat(plotcmd,&info)){
1.158     brouard  12818:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12819:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12820:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12821:     }else
                   12822:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12823: #ifdef __unix
1.126     brouard  12824:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12825:     if(!stat(plotcmd,&info)){
1.158     brouard  12826:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12827:     }else
                   12828:       strcpy(pplotcmd,plotcmd);
                   12829: #endif
                   12830:   }else
                   12831:     strcpy(pplotcmd,plotcmd);
                   12832:   
                   12833:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12834:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292   ! brouard  12835:   strcpy(pplotcmd,plotcmd);
1.227     brouard  12836:   
1.126     brouard  12837:   if((outcmd=system(plotcmd)) != 0){
1.292   ! brouard  12838:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12839:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12840:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292   ! brouard  12841:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  12842:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292   ! brouard  12843:       strcpy(plotcmd,pplotcmd);
        !          12844:     }
1.126     brouard  12845:   }
1.158     brouard  12846:   printf(" Successful, please wait...");
1.126     brouard  12847:   while (z[0] != 'q') {
                   12848:     /* chdir(path); */
1.154     brouard  12849:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12850:     scanf("%s",z);
                   12851: /*     if (z[0] == 'c') system("./imach"); */
                   12852:     if (z[0] == 'e') {
1.158     brouard  12853: #ifdef __APPLE__
1.152     brouard  12854:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12855: #elif __linux
                   12856:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12857: #else
1.152     brouard  12858:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12859: #endif
                   12860:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12861:       system(pplotcmd);
1.126     brouard  12862:     }
                   12863:     else if (z[0] == 'g') system(plotcmd);
                   12864:     else if (z[0] == 'q') exit(0);
                   12865:   }
1.227     brouard  12866: end:
1.126     brouard  12867:   while (z[0] != 'q') {
1.195     brouard  12868:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12869:     scanf("%s",z);
                   12870:   }
1.283     brouard  12871:   printf("End\n");
1.282     brouard  12872:   exit(0);
1.126     brouard  12873: }

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