Annotation of imach/src/imach.c, revision 1.295

1.295   ! brouard     1: /* $Id: imach.c,v 1.294 2019/05/16 14:54:33 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.295   ! brouard     4:   Revision 1.294  2019/05/16 14:54:33  brouard
        !             5:   Summary: There was some wrong lines added
        !             6: 
1.294     brouard     7:   Revision 1.293  2019/05/09 15:17:34  brouard
                      8:   *** empty log message ***
                      9: 
1.293     brouard    10:   Revision 1.292  2019/05/09 14:17:20  brouard
                     11:   Summary: Some updates
                     12: 
1.292     brouard    13:   Revision 1.291  2019/05/09 13:44:18  brouard
                     14:   Summary: Before ncovmax
                     15: 
1.291     brouard    16:   Revision 1.290  2019/05/09 13:39:37  brouard
                     17:   Summary: 0.99r18 unlimited number of individuals
                     18: 
                     19:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                     20: 
1.290     brouard    21:   Revision 1.289  2018/12/13 09:16:26  brouard
                     22:   Summary: Bug for young ages (<-30) will be in r17
                     23: 
1.289     brouard    24:   Revision 1.288  2018/05/02 20:58:27  brouard
                     25:   Summary: Some bugs fixed
                     26: 
1.288     brouard    27:   Revision 1.287  2018/05/01 17:57:25  brouard
                     28:   Summary: Bug fixed by providing frequencies only for non missing covariates
                     29: 
1.287     brouard    30:   Revision 1.286  2018/04/27 14:27:04  brouard
                     31:   Summary: some minor bugs
                     32: 
1.286     brouard    33:   Revision 1.285  2018/04/21 21:02:16  brouard
                     34:   Summary: Some bugs fixed, valgrind tested
                     35: 
1.285     brouard    36:   Revision 1.284  2018/04/20 05:22:13  brouard
                     37:   Summary: Computing mean and stdeviation of fixed quantitative variables
                     38: 
1.284     brouard    39:   Revision 1.283  2018/04/19 14:49:16  brouard
                     40:   Summary: Some minor bugs fixed
                     41: 
1.283     brouard    42:   Revision 1.282  2018/02/27 22:50:02  brouard
                     43:   *** empty log message ***
                     44: 
1.282     brouard    45:   Revision 1.281  2018/02/27 19:25:23  brouard
                     46:   Summary: Adding second argument for quitting
                     47: 
1.281     brouard    48:   Revision 1.280  2018/02/21 07:58:13  brouard
                     49:   Summary: 0.99r15
                     50: 
                     51:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                     52: 
1.280     brouard    53:   Revision 1.279  2017/07/20 13:35:01  brouard
                     54:   Summary: temporary working
                     55: 
1.279     brouard    56:   Revision 1.278  2017/07/19 14:09:02  brouard
                     57:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                     58: 
1.278     brouard    59:   Revision 1.277  2017/07/17 08:53:49  brouard
                     60:   Summary: BOM files can be read now
                     61: 
1.277     brouard    62:   Revision 1.276  2017/06/30 15:48:31  brouard
                     63:   Summary: Graphs improvements
                     64: 
1.276     brouard    65:   Revision 1.275  2017/06/30 13:39:33  brouard
                     66:   Summary: Saito's color
                     67: 
1.275     brouard    68:   Revision 1.274  2017/06/29 09:47:08  brouard
                     69:   Summary: Version 0.99r14
                     70: 
1.274     brouard    71:   Revision 1.273  2017/06/27 11:06:02  brouard
                     72:   Summary: More documentation on projections
                     73: 
1.273     brouard    74:   Revision 1.272  2017/06/27 10:22:40  brouard
                     75:   Summary: Color of backprojection changed from 6 to 5(yellow)
                     76: 
1.272     brouard    77:   Revision 1.271  2017/06/27 10:17:50  brouard
                     78:   Summary: Some bug with rint
                     79: 
1.271     brouard    80:   Revision 1.270  2017/05/24 05:45:29  brouard
                     81:   *** empty log message ***
                     82: 
1.270     brouard    83:   Revision 1.269  2017/05/23 08:39:25  brouard
                     84:   Summary: Code into subroutine, cleanings
                     85: 
1.269     brouard    86:   Revision 1.268  2017/05/18 20:09:32  brouard
                     87:   Summary: backprojection and confidence intervals of backprevalence
                     88: 
1.268     brouard    89:   Revision 1.267  2017/05/13 10:25:05  brouard
                     90:   Summary: temporary save for backprojection
                     91: 
1.267     brouard    92:   Revision 1.266  2017/05/13 07:26:12  brouard
                     93:   Summary: Version 0.99r13 (improvements and bugs fixed)
                     94: 
1.266     brouard    95:   Revision 1.265  2017/04/26 16:22:11  brouard
                     96:   Summary: imach 0.99r13 Some bugs fixed
                     97: 
1.265     brouard    98:   Revision 1.264  2017/04/26 06:01:29  brouard
                     99:   Summary: Labels in graphs
                    100: 
1.264     brouard   101:   Revision 1.263  2017/04/24 15:23:15  brouard
                    102:   Summary: to save
                    103: 
1.263     brouard   104:   Revision 1.262  2017/04/18 16:48:12  brouard
                    105:   *** empty log message ***
                    106: 
1.262     brouard   107:   Revision 1.261  2017/04/05 10:14:09  brouard
                    108:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    109: 
1.261     brouard   110:   Revision 1.260  2017/04/04 17:46:59  brouard
                    111:   Summary: Gnuplot indexations fixed (humm)
                    112: 
1.260     brouard   113:   Revision 1.259  2017/04/04 13:01:16  brouard
                    114:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    115: 
1.259     brouard   116:   Revision 1.258  2017/04/03 10:17:47  brouard
                    117:   Summary: Version 0.99r12
                    118: 
                    119:   Some cleanings, conformed with updated documentation.
                    120: 
1.258     brouard   121:   Revision 1.257  2017/03/29 16:53:30  brouard
                    122:   Summary: Temp
                    123: 
1.257     brouard   124:   Revision 1.256  2017/03/27 05:50:23  brouard
                    125:   Summary: Temporary
                    126: 
1.256     brouard   127:   Revision 1.255  2017/03/08 16:02:28  brouard
                    128:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    129: 
1.255     brouard   130:   Revision 1.254  2017/03/08 07:13:00  brouard
                    131:   Summary: Fixing data parameter line
                    132: 
1.254     brouard   133:   Revision 1.253  2016/12/15 11:59:41  brouard
                    134:   Summary: 0.99 in progress
                    135: 
1.253     brouard   136:   Revision 1.252  2016/09/15 21:15:37  brouard
                    137:   *** empty log message ***
                    138: 
1.252     brouard   139:   Revision 1.251  2016/09/15 15:01:13  brouard
                    140:   Summary: not working
                    141: 
1.251     brouard   142:   Revision 1.250  2016/09/08 16:07:27  brouard
                    143:   Summary: continue
                    144: 
1.250     brouard   145:   Revision 1.249  2016/09/07 17:14:18  brouard
                    146:   Summary: Starting values from frequencies
                    147: 
1.249     brouard   148:   Revision 1.248  2016/09/07 14:10:18  brouard
                    149:   *** empty log message ***
                    150: 
1.248     brouard   151:   Revision 1.247  2016/09/02 11:11:21  brouard
                    152:   *** empty log message ***
                    153: 
1.247     brouard   154:   Revision 1.246  2016/09/02 08:49:22  brouard
                    155:   *** empty log message ***
                    156: 
1.246     brouard   157:   Revision 1.245  2016/09/02 07:25:01  brouard
                    158:   *** empty log message ***
                    159: 
1.245     brouard   160:   Revision 1.244  2016/09/02 07:17:34  brouard
                    161:   *** empty log message ***
                    162: 
1.244     brouard   163:   Revision 1.243  2016/09/02 06:45:35  brouard
                    164:   *** empty log message ***
                    165: 
1.243     brouard   166:   Revision 1.242  2016/08/30 15:01:20  brouard
                    167:   Summary: Fixing a lots
                    168: 
1.242     brouard   169:   Revision 1.241  2016/08/29 17:17:25  brouard
                    170:   Summary: gnuplot problem in Back projection to fix
                    171: 
1.241     brouard   172:   Revision 1.240  2016/08/29 07:53:18  brouard
                    173:   Summary: Better
                    174: 
1.240     brouard   175:   Revision 1.239  2016/08/26 15:51:03  brouard
                    176:   Summary: Improvement in Powell output in order to copy and paste
                    177: 
                    178:   Author:
                    179: 
1.239     brouard   180:   Revision 1.238  2016/08/26 14:23:35  brouard
                    181:   Summary: Starting tests of 0.99
                    182: 
1.238     brouard   183:   Revision 1.237  2016/08/26 09:20:19  brouard
                    184:   Summary: to valgrind
                    185: 
1.237     brouard   186:   Revision 1.236  2016/08/25 10:50:18  brouard
                    187:   *** empty log message ***
                    188: 
1.236     brouard   189:   Revision 1.235  2016/08/25 06:59:23  brouard
                    190:   *** empty log message ***
                    191: 
1.235     brouard   192:   Revision 1.234  2016/08/23 16:51:20  brouard
                    193:   *** empty log message ***
                    194: 
1.234     brouard   195:   Revision 1.233  2016/08/23 07:40:50  brouard
                    196:   Summary: not working
                    197: 
1.233     brouard   198:   Revision 1.232  2016/08/22 14:20:21  brouard
                    199:   Summary: not working
                    200: 
1.232     brouard   201:   Revision 1.231  2016/08/22 07:17:15  brouard
                    202:   Summary: not working
                    203: 
1.231     brouard   204:   Revision 1.230  2016/08/22 06:55:53  brouard
                    205:   Summary: Not working
                    206: 
1.230     brouard   207:   Revision 1.229  2016/07/23 09:45:53  brouard
                    208:   Summary: Completing for func too
                    209: 
1.229     brouard   210:   Revision 1.228  2016/07/22 17:45:30  brouard
                    211:   Summary: Fixing some arrays, still debugging
                    212: 
1.227     brouard   213:   Revision 1.226  2016/07/12 18:42:34  brouard
                    214:   Summary: temp
                    215: 
1.226     brouard   216:   Revision 1.225  2016/07/12 08:40:03  brouard
                    217:   Summary: saving but not running
                    218: 
1.225     brouard   219:   Revision 1.224  2016/07/01 13:16:01  brouard
                    220:   Summary: Fixes
                    221: 
1.224     brouard   222:   Revision 1.223  2016/02/19 09:23:35  brouard
                    223:   Summary: temporary
                    224: 
1.223     brouard   225:   Revision 1.222  2016/02/17 08:14:50  brouard
                    226:   Summary: Probably last 0.98 stable version 0.98r6
                    227: 
1.222     brouard   228:   Revision 1.221  2016/02/15 23:35:36  brouard
                    229:   Summary: minor bug
                    230: 
1.220     brouard   231:   Revision 1.219  2016/02/15 00:48:12  brouard
                    232:   *** empty log message ***
                    233: 
1.219     brouard   234:   Revision 1.218  2016/02/12 11:29:23  brouard
                    235:   Summary: 0.99 Back projections
                    236: 
1.218     brouard   237:   Revision 1.217  2015/12/23 17:18:31  brouard
                    238:   Summary: Experimental backcast
                    239: 
1.217     brouard   240:   Revision 1.216  2015/12/18 17:32:11  brouard
                    241:   Summary: 0.98r4 Warning and status=-2
                    242: 
                    243:   Version 0.98r4 is now:
                    244:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    245:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    246:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    247: 
1.216     brouard   248:   Revision 1.215  2015/12/16 08:52:24  brouard
                    249:   Summary: 0.98r4 working
                    250: 
1.215     brouard   251:   Revision 1.214  2015/12/16 06:57:54  brouard
                    252:   Summary: temporary not working
                    253: 
1.214     brouard   254:   Revision 1.213  2015/12/11 18:22:17  brouard
                    255:   Summary: 0.98r4
                    256: 
1.213     brouard   257:   Revision 1.212  2015/11/21 12:47:24  brouard
                    258:   Summary: minor typo
                    259: 
1.212     brouard   260:   Revision 1.211  2015/11/21 12:41:11  brouard
                    261:   Summary: 0.98r3 with some graph of projected cross-sectional
                    262: 
                    263:   Author: Nicolas Brouard
                    264: 
1.211     brouard   265:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   266:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   267:   Summary: Adding ftolpl parameter
                    268:   Author: N Brouard
                    269: 
                    270:   We had difficulties to get smoothed confidence intervals. It was due
                    271:   to the period prevalence which wasn't computed accurately. The inner
                    272:   parameter ftolpl is now an outer parameter of the .imach parameter
                    273:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    274:   computation are long.
                    275: 
1.209     brouard   276:   Revision 1.208  2015/11/17 14:31:57  brouard
                    277:   Summary: temporary
                    278: 
1.208     brouard   279:   Revision 1.207  2015/10/27 17:36:57  brouard
                    280:   *** empty log message ***
                    281: 
1.207     brouard   282:   Revision 1.206  2015/10/24 07:14:11  brouard
                    283:   *** empty log message ***
                    284: 
1.206     brouard   285:   Revision 1.205  2015/10/23 15:50:53  brouard
                    286:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    287: 
1.205     brouard   288:   Revision 1.204  2015/10/01 16:20:26  brouard
                    289:   Summary: Some new graphs of contribution to likelihood
                    290: 
1.204     brouard   291:   Revision 1.203  2015/09/30 17:45:14  brouard
                    292:   Summary: looking at better estimation of the hessian
                    293: 
                    294:   Also a better criteria for convergence to the period prevalence And
                    295:   therefore adding the number of years needed to converge. (The
                    296:   prevalence in any alive state shold sum to one
                    297: 
1.203     brouard   298:   Revision 1.202  2015/09/22 19:45:16  brouard
                    299:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    300: 
1.202     brouard   301:   Revision 1.201  2015/09/15 17:34:58  brouard
                    302:   Summary: 0.98r0
                    303: 
                    304:   - Some new graphs like suvival functions
                    305:   - Some bugs fixed like model=1+age+V2.
                    306: 
1.201     brouard   307:   Revision 1.200  2015/09/09 16:53:55  brouard
                    308:   Summary: Big bug thanks to Flavia
                    309: 
                    310:   Even model=1+age+V2. did not work anymore
                    311: 
1.200     brouard   312:   Revision 1.199  2015/09/07 14:09:23  brouard
                    313:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    314: 
1.199     brouard   315:   Revision 1.198  2015/09/03 07:14:39  brouard
                    316:   Summary: 0.98q5 Flavia
                    317: 
1.198     brouard   318:   Revision 1.197  2015/09/01 18:24:39  brouard
                    319:   *** empty log message ***
                    320: 
1.197     brouard   321:   Revision 1.196  2015/08/18 23:17:52  brouard
                    322:   Summary: 0.98q5
                    323: 
1.196     brouard   324:   Revision 1.195  2015/08/18 16:28:39  brouard
                    325:   Summary: Adding a hack for testing purpose
                    326: 
                    327:   After reading the title, ftol and model lines, if the comment line has
                    328:   a q, starting with #q, the answer at the end of the run is quit. It
                    329:   permits to run test files in batch with ctest. The former workaround was
                    330:   $ echo q | imach foo.imach
                    331: 
1.195     brouard   332:   Revision 1.194  2015/08/18 13:32:00  brouard
                    333:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    334: 
1.194     brouard   335:   Revision 1.193  2015/08/04 07:17:42  brouard
                    336:   Summary: 0.98q4
                    337: 
1.193     brouard   338:   Revision 1.192  2015/07/16 16:49:02  brouard
                    339:   Summary: Fixing some outputs
                    340: 
1.192     brouard   341:   Revision 1.191  2015/07/14 10:00:33  brouard
                    342:   Summary: Some fixes
                    343: 
1.191     brouard   344:   Revision 1.190  2015/05/05 08:51:13  brouard
                    345:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    346: 
                    347:   Fix 1+age+.
                    348: 
1.190     brouard   349:   Revision 1.189  2015/04/30 14:45:16  brouard
                    350:   Summary: 0.98q2
                    351: 
1.189     brouard   352:   Revision 1.188  2015/04/30 08:27:53  brouard
                    353:   *** empty log message ***
                    354: 
1.188     brouard   355:   Revision 1.187  2015/04/29 09:11:15  brouard
                    356:   *** empty log message ***
                    357: 
1.187     brouard   358:   Revision 1.186  2015/04/23 12:01:52  brouard
                    359:   Summary: V1*age is working now, version 0.98q1
                    360: 
                    361:   Some codes had been disabled in order to simplify and Vn*age was
                    362:   working in the optimization phase, ie, giving correct MLE parameters,
                    363:   but, as usual, outputs were not correct and program core dumped.
                    364: 
1.186     brouard   365:   Revision 1.185  2015/03/11 13:26:42  brouard
                    366:   Summary: Inclusion of compile and links command line for Intel Compiler
                    367: 
1.185     brouard   368:   Revision 1.184  2015/03/11 11:52:39  brouard
                    369:   Summary: Back from Windows 8. Intel Compiler
                    370: 
1.184     brouard   371:   Revision 1.183  2015/03/10 20:34:32  brouard
                    372:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    373: 
                    374:   We use directest instead of original Powell test; probably no
                    375:   incidence on the results, but better justifications;
                    376:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    377:   wrong results.
                    378: 
1.183     brouard   379:   Revision 1.182  2015/02/12 08:19:57  brouard
                    380:   Summary: Trying to keep directest which seems simpler and more general
                    381:   Author: Nicolas Brouard
                    382: 
1.182     brouard   383:   Revision 1.181  2015/02/11 23:22:24  brouard
                    384:   Summary: Comments on Powell added
                    385: 
                    386:   Author:
                    387: 
1.181     brouard   388:   Revision 1.180  2015/02/11 17:33:45  brouard
                    389:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    390: 
1.180     brouard   391:   Revision 1.179  2015/01/04 09:57:06  brouard
                    392:   Summary: back to OS/X
                    393: 
1.179     brouard   394:   Revision 1.178  2015/01/04 09:35:48  brouard
                    395:   *** empty log message ***
                    396: 
1.178     brouard   397:   Revision 1.177  2015/01/03 18:40:56  brouard
                    398:   Summary: Still testing ilc32 on OSX
                    399: 
1.177     brouard   400:   Revision 1.176  2015/01/03 16:45:04  brouard
                    401:   *** empty log message ***
                    402: 
1.176     brouard   403:   Revision 1.175  2015/01/03 16:33:42  brouard
                    404:   *** empty log message ***
                    405: 
1.175     brouard   406:   Revision 1.174  2015/01/03 16:15:49  brouard
                    407:   Summary: Still in cross-compilation
                    408: 
1.174     brouard   409:   Revision 1.173  2015/01/03 12:06:26  brouard
                    410:   Summary: trying to detect cross-compilation
                    411: 
1.173     brouard   412:   Revision 1.172  2014/12/27 12:07:47  brouard
                    413:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    414: 
1.172     brouard   415:   Revision 1.171  2014/12/23 13:26:59  brouard
                    416:   Summary: Back from Visual C
                    417: 
                    418:   Still problem with utsname.h on Windows
                    419: 
1.171     brouard   420:   Revision 1.170  2014/12/23 11:17:12  brouard
                    421:   Summary: Cleaning some \%% back to %%
                    422: 
                    423:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    424: 
1.170     brouard   425:   Revision 1.169  2014/12/22 23:08:31  brouard
                    426:   Summary: 0.98p
                    427: 
                    428:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    429: 
1.169     brouard   430:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   431:   Summary: update
1.169     brouard   432: 
1.168     brouard   433:   Revision 1.167  2014/12/22 13:50:56  brouard
                    434:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    435: 
                    436:   Testing on Linux 64
                    437: 
1.167     brouard   438:   Revision 1.166  2014/12/22 11:40:47  brouard
                    439:   *** empty log message ***
                    440: 
1.166     brouard   441:   Revision 1.165  2014/12/16 11:20:36  brouard
                    442:   Summary: After compiling on Visual C
                    443: 
                    444:   * imach.c (Module): Merging 1.61 to 1.162
                    445: 
1.165     brouard   446:   Revision 1.164  2014/12/16 10:52:11  brouard
                    447:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    448: 
                    449:   * imach.c (Module): Merging 1.61 to 1.162
                    450: 
1.164     brouard   451:   Revision 1.163  2014/12/16 10:30:11  brouard
                    452:   * imach.c (Module): Merging 1.61 to 1.162
                    453: 
1.163     brouard   454:   Revision 1.162  2014/09/25 11:43:39  brouard
                    455:   Summary: temporary backup 0.99!
                    456: 
1.162     brouard   457:   Revision 1.1  2014/09/16 11:06:58  brouard
                    458:   Summary: With some code (wrong) for nlopt
                    459: 
                    460:   Author:
                    461: 
                    462:   Revision 1.161  2014/09/15 20:41:41  brouard
                    463:   Summary: Problem with macro SQR on Intel compiler
                    464: 
1.161     brouard   465:   Revision 1.160  2014/09/02 09:24:05  brouard
                    466:   *** empty log message ***
                    467: 
1.160     brouard   468:   Revision 1.159  2014/09/01 10:34:10  brouard
                    469:   Summary: WIN32
                    470:   Author: Brouard
                    471: 
1.159     brouard   472:   Revision 1.158  2014/08/27 17:11:51  brouard
                    473:   *** empty log message ***
                    474: 
1.158     brouard   475:   Revision 1.157  2014/08/27 16:26:55  brouard
                    476:   Summary: Preparing windows Visual studio version
                    477:   Author: Brouard
                    478: 
                    479:   In order to compile on Visual studio, time.h is now correct and time_t
                    480:   and tm struct should be used. difftime should be used but sometimes I
                    481:   just make the differences in raw time format (time(&now).
                    482:   Trying to suppress #ifdef LINUX
                    483:   Add xdg-open for __linux in order to open default browser.
                    484: 
1.157     brouard   485:   Revision 1.156  2014/08/25 20:10:10  brouard
                    486:   *** empty log message ***
                    487: 
1.156     brouard   488:   Revision 1.155  2014/08/25 18:32:34  brouard
                    489:   Summary: New compile, minor changes
                    490:   Author: Brouard
                    491: 
1.155     brouard   492:   Revision 1.154  2014/06/20 17:32:08  brouard
                    493:   Summary: Outputs now all graphs of convergence to period prevalence
                    494: 
1.154     brouard   495:   Revision 1.153  2014/06/20 16:45:46  brouard
                    496:   Summary: If 3 live state, convergence to period prevalence on same graph
                    497:   Author: Brouard
                    498: 
1.153     brouard   499:   Revision 1.152  2014/06/18 17:54:09  brouard
                    500:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    501: 
1.152     brouard   502:   Revision 1.151  2014/06/18 16:43:30  brouard
                    503:   *** empty log message ***
                    504: 
1.151     brouard   505:   Revision 1.150  2014/06/18 16:42:35  brouard
                    506:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    507:   Author: brouard
                    508: 
1.150     brouard   509:   Revision 1.149  2014/06/18 15:51:14  brouard
                    510:   Summary: Some fixes in parameter files errors
                    511:   Author: Nicolas Brouard
                    512: 
1.149     brouard   513:   Revision 1.148  2014/06/17 17:38:48  brouard
                    514:   Summary: Nothing new
                    515:   Author: Brouard
                    516: 
                    517:   Just a new packaging for OS/X version 0.98nS
                    518: 
1.148     brouard   519:   Revision 1.147  2014/06/16 10:33:11  brouard
                    520:   *** empty log message ***
                    521: 
1.147     brouard   522:   Revision 1.146  2014/06/16 10:20:28  brouard
                    523:   Summary: Merge
                    524:   Author: Brouard
                    525: 
                    526:   Merge, before building revised version.
                    527: 
1.146     brouard   528:   Revision 1.145  2014/06/10 21:23:15  brouard
                    529:   Summary: Debugging with valgrind
                    530:   Author: Nicolas Brouard
                    531: 
                    532:   Lot of changes in order to output the results with some covariates
                    533:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    534:   improve the code.
                    535:   No more memory valgrind error but a lot has to be done in order to
                    536:   continue the work of splitting the code into subroutines.
                    537:   Also, decodemodel has been improved. Tricode is still not
                    538:   optimal. nbcode should be improved. Documentation has been added in
                    539:   the source code.
                    540: 
1.144     brouard   541:   Revision 1.143  2014/01/26 09:45:38  brouard
                    542:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    543: 
                    544:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    545:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    546: 
1.143     brouard   547:   Revision 1.142  2014/01/26 03:57:36  brouard
                    548:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    549: 
                    550:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    551: 
1.142     brouard   552:   Revision 1.141  2014/01/26 02:42:01  brouard
                    553:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    554: 
1.141     brouard   555:   Revision 1.140  2011/09/02 10:37:54  brouard
                    556:   Summary: times.h is ok with mingw32 now.
                    557: 
1.140     brouard   558:   Revision 1.139  2010/06/14 07:50:17  brouard
                    559:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    560:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    561: 
1.139     brouard   562:   Revision 1.138  2010/04/30 18:19:40  brouard
                    563:   *** empty log message ***
                    564: 
1.138     brouard   565:   Revision 1.137  2010/04/29 18:11:38  brouard
                    566:   (Module): Checking covariates for more complex models
                    567:   than V1+V2. A lot of change to be done. Unstable.
                    568: 
1.137     brouard   569:   Revision 1.136  2010/04/26 20:30:53  brouard
                    570:   (Module): merging some libgsl code. Fixing computation
                    571:   of likelione (using inter/intrapolation if mle = 0) in order to
                    572:   get same likelihood as if mle=1.
                    573:   Some cleaning of code and comments added.
                    574: 
1.136     brouard   575:   Revision 1.135  2009/10/29 15:33:14  brouard
                    576:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    577: 
1.135     brouard   578:   Revision 1.134  2009/10/29 13:18:53  brouard
                    579:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    580: 
1.134     brouard   581:   Revision 1.133  2009/07/06 10:21:25  brouard
                    582:   just nforces
                    583: 
1.133     brouard   584:   Revision 1.132  2009/07/06 08:22:05  brouard
                    585:   Many tings
                    586: 
1.132     brouard   587:   Revision 1.131  2009/06/20 16:22:47  brouard
                    588:   Some dimensions resccaled
                    589: 
1.131     brouard   590:   Revision 1.130  2009/05/26 06:44:34  brouard
                    591:   (Module): Max Covariate is now set to 20 instead of 8. A
                    592:   lot of cleaning with variables initialized to 0. Trying to make
                    593:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    594: 
1.130     brouard   595:   Revision 1.129  2007/08/31 13:49:27  lievre
                    596:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    597: 
1.129     lievre    598:   Revision 1.128  2006/06/30 13:02:05  brouard
                    599:   (Module): Clarifications on computing e.j
                    600: 
1.128     brouard   601:   Revision 1.127  2006/04/28 18:11:50  brouard
                    602:   (Module): Yes the sum of survivors was wrong since
                    603:   imach-114 because nhstepm was no more computed in the age
                    604:   loop. Now we define nhstepma in the age loop.
                    605:   (Module): In order to speed up (in case of numerous covariates) we
                    606:   compute health expectancies (without variances) in a first step
                    607:   and then all the health expectancies with variances or standard
                    608:   deviation (needs data from the Hessian matrices) which slows the
                    609:   computation.
                    610:   In the future we should be able to stop the program is only health
                    611:   expectancies and graph are needed without standard deviations.
                    612: 
1.127     brouard   613:   Revision 1.126  2006/04/28 17:23:28  brouard
                    614:   (Module): Yes the sum of survivors was wrong since
                    615:   imach-114 because nhstepm was no more computed in the age
                    616:   loop. Now we define nhstepma in the age loop.
                    617:   Version 0.98h
                    618: 
1.126     brouard   619:   Revision 1.125  2006/04/04 15:20:31  lievre
                    620:   Errors in calculation of health expectancies. Age was not initialized.
                    621:   Forecasting file added.
                    622: 
                    623:   Revision 1.124  2006/03/22 17:13:53  lievre
                    624:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    625:   The log-likelihood is printed in the log file
                    626: 
                    627:   Revision 1.123  2006/03/20 10:52:43  brouard
                    628:   * imach.c (Module): <title> changed, corresponds to .htm file
                    629:   name. <head> headers where missing.
                    630: 
                    631:   * imach.c (Module): Weights can have a decimal point as for
                    632:   English (a comma might work with a correct LC_NUMERIC environment,
                    633:   otherwise the weight is truncated).
                    634:   Modification of warning when the covariates values are not 0 or
                    635:   1.
                    636:   Version 0.98g
                    637: 
                    638:   Revision 1.122  2006/03/20 09:45:41  brouard
                    639:   (Module): Weights can have a decimal point as for
                    640:   English (a comma might work with a correct LC_NUMERIC environment,
                    641:   otherwise the weight is truncated).
                    642:   Modification of warning when the covariates values are not 0 or
                    643:   1.
                    644:   Version 0.98g
                    645: 
                    646:   Revision 1.121  2006/03/16 17:45:01  lievre
                    647:   * imach.c (Module): Comments concerning covariates added
                    648: 
                    649:   * imach.c (Module): refinements in the computation of lli if
                    650:   status=-2 in order to have more reliable computation if stepm is
                    651:   not 1 month. Version 0.98f
                    652: 
                    653:   Revision 1.120  2006/03/16 15:10:38  lievre
                    654:   (Module): refinements in the computation of lli if
                    655:   status=-2 in order to have more reliable computation if stepm is
                    656:   not 1 month. Version 0.98f
                    657: 
                    658:   Revision 1.119  2006/03/15 17:42:26  brouard
                    659:   (Module): Bug if status = -2, the loglikelihood was
                    660:   computed as likelihood omitting the logarithm. Version O.98e
                    661: 
                    662:   Revision 1.118  2006/03/14 18:20:07  brouard
                    663:   (Module): varevsij Comments added explaining the second
                    664:   table of variances if popbased=1 .
                    665:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    666:   (Module): Function pstamp added
                    667:   (Module): Version 0.98d
                    668: 
                    669:   Revision 1.117  2006/03/14 17:16:22  brouard
                    670:   (Module): varevsij Comments added explaining the second
                    671:   table of variances if popbased=1 .
                    672:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    673:   (Module): Function pstamp added
                    674:   (Module): Version 0.98d
                    675: 
                    676:   Revision 1.116  2006/03/06 10:29:27  brouard
                    677:   (Module): Variance-covariance wrong links and
                    678:   varian-covariance of ej. is needed (Saito).
                    679: 
                    680:   Revision 1.115  2006/02/27 12:17:45  brouard
                    681:   (Module): One freematrix added in mlikeli! 0.98c
                    682: 
                    683:   Revision 1.114  2006/02/26 12:57:58  brouard
                    684:   (Module): Some improvements in processing parameter
                    685:   filename with strsep.
                    686: 
                    687:   Revision 1.113  2006/02/24 14:20:24  brouard
                    688:   (Module): Memory leaks checks with valgrind and:
                    689:   datafile was not closed, some imatrix were not freed and on matrix
                    690:   allocation too.
                    691: 
                    692:   Revision 1.112  2006/01/30 09:55:26  brouard
                    693:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    694: 
                    695:   Revision 1.111  2006/01/25 20:38:18  brouard
                    696:   (Module): Lots of cleaning and bugs added (Gompertz)
                    697:   (Module): Comments can be added in data file. Missing date values
                    698:   can be a simple dot '.'.
                    699: 
                    700:   Revision 1.110  2006/01/25 00:51:50  brouard
                    701:   (Module): Lots of cleaning and bugs added (Gompertz)
                    702: 
                    703:   Revision 1.109  2006/01/24 19:37:15  brouard
                    704:   (Module): Comments (lines starting with a #) are allowed in data.
                    705: 
                    706:   Revision 1.108  2006/01/19 18:05:42  lievre
                    707:   Gnuplot problem appeared...
                    708:   To be fixed
                    709: 
                    710:   Revision 1.107  2006/01/19 16:20:37  brouard
                    711:   Test existence of gnuplot in imach path
                    712: 
                    713:   Revision 1.106  2006/01/19 13:24:36  brouard
                    714:   Some cleaning and links added in html output
                    715: 
                    716:   Revision 1.105  2006/01/05 20:23:19  lievre
                    717:   *** empty log message ***
                    718: 
                    719:   Revision 1.104  2005/09/30 16:11:43  lievre
                    720:   (Module): sump fixed, loop imx fixed, and simplifications.
                    721:   (Module): If the status is missing at the last wave but we know
                    722:   that the person is alive, then we can code his/her status as -2
                    723:   (instead of missing=-1 in earlier versions) and his/her
                    724:   contributions to the likelihood is 1 - Prob of dying from last
                    725:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    726:   the healthy state at last known wave). Version is 0.98
                    727: 
                    728:   Revision 1.103  2005/09/30 15:54:49  lievre
                    729:   (Module): sump fixed, loop imx fixed, and simplifications.
                    730: 
                    731:   Revision 1.102  2004/09/15 17:31:30  brouard
                    732:   Add the possibility to read data file including tab characters.
                    733: 
                    734:   Revision 1.101  2004/09/15 10:38:38  brouard
                    735:   Fix on curr_time
                    736: 
                    737:   Revision 1.100  2004/07/12 18:29:06  brouard
                    738:   Add version for Mac OS X. Just define UNIX in Makefile
                    739: 
                    740:   Revision 1.99  2004/06/05 08:57:40  brouard
                    741:   *** empty log message ***
                    742: 
                    743:   Revision 1.98  2004/05/16 15:05:56  brouard
                    744:   New version 0.97 . First attempt to estimate force of mortality
                    745:   directly from the data i.e. without the need of knowing the health
                    746:   state at each age, but using a Gompertz model: log u =a + b*age .
                    747:   This is the basic analysis of mortality and should be done before any
                    748:   other analysis, in order to test if the mortality estimated from the
                    749:   cross-longitudinal survey is different from the mortality estimated
                    750:   from other sources like vital statistic data.
                    751: 
                    752:   The same imach parameter file can be used but the option for mle should be -3.
                    753: 
1.133     brouard   754:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   755:   former routines in order to include the new code within the former code.
                    756: 
                    757:   The output is very simple: only an estimate of the intercept and of
                    758:   the slope with 95% confident intervals.
                    759: 
                    760:   Current limitations:
                    761:   A) Even if you enter covariates, i.e. with the
                    762:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    763:   B) There is no computation of Life Expectancy nor Life Table.
                    764: 
                    765:   Revision 1.97  2004/02/20 13:25:42  lievre
                    766:   Version 0.96d. Population forecasting command line is (temporarily)
                    767:   suppressed.
                    768: 
                    769:   Revision 1.96  2003/07/15 15:38:55  brouard
                    770:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    771:   rewritten within the same printf. Workaround: many printfs.
                    772: 
                    773:   Revision 1.95  2003/07/08 07:54:34  brouard
                    774:   * imach.c (Repository):
                    775:   (Repository): Using imachwizard code to output a more meaningful covariance
                    776:   matrix (cov(a12,c31) instead of numbers.
                    777: 
                    778:   Revision 1.94  2003/06/27 13:00:02  brouard
                    779:   Just cleaning
                    780: 
                    781:   Revision 1.93  2003/06/25 16:33:55  brouard
                    782:   (Module): On windows (cygwin) function asctime_r doesn't
                    783:   exist so I changed back to asctime which exists.
                    784:   (Module): Version 0.96b
                    785: 
                    786:   Revision 1.92  2003/06/25 16:30:45  brouard
                    787:   (Module): On windows (cygwin) function asctime_r doesn't
                    788:   exist so I changed back to asctime which exists.
                    789: 
                    790:   Revision 1.91  2003/06/25 15:30:29  brouard
                    791:   * imach.c (Repository): Duplicated warning errors corrected.
                    792:   (Repository): Elapsed time after each iteration is now output. It
                    793:   helps to forecast when convergence will be reached. Elapsed time
                    794:   is stamped in powell.  We created a new html file for the graphs
                    795:   concerning matrix of covariance. It has extension -cov.htm.
                    796: 
                    797:   Revision 1.90  2003/06/24 12:34:15  brouard
                    798:   (Module): Some bugs corrected for windows. Also, when
                    799:   mle=-1 a template is output in file "or"mypar.txt with the design
                    800:   of the covariance matrix to be input.
                    801: 
                    802:   Revision 1.89  2003/06/24 12:30:52  brouard
                    803:   (Module): Some bugs corrected for windows. Also, when
                    804:   mle=-1 a template is output in file "or"mypar.txt with the design
                    805:   of the covariance matrix to be input.
                    806: 
                    807:   Revision 1.88  2003/06/23 17:54:56  brouard
                    808:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    809: 
                    810:   Revision 1.87  2003/06/18 12:26:01  brouard
                    811:   Version 0.96
                    812: 
                    813:   Revision 1.86  2003/06/17 20:04:08  brouard
                    814:   (Module): Change position of html and gnuplot routines and added
                    815:   routine fileappend.
                    816: 
                    817:   Revision 1.85  2003/06/17 13:12:43  brouard
                    818:   * imach.c (Repository): Check when date of death was earlier that
                    819:   current date of interview. It may happen when the death was just
                    820:   prior to the death. In this case, dh was negative and likelihood
                    821:   was wrong (infinity). We still send an "Error" but patch by
                    822:   assuming that the date of death was just one stepm after the
                    823:   interview.
                    824:   (Repository): Because some people have very long ID (first column)
                    825:   we changed int to long in num[] and we added a new lvector for
                    826:   memory allocation. But we also truncated to 8 characters (left
                    827:   truncation)
                    828:   (Repository): No more line truncation errors.
                    829: 
                    830:   Revision 1.84  2003/06/13 21:44:43  brouard
                    831:   * imach.c (Repository): Replace "freqsummary" at a correct
                    832:   place. It differs from routine "prevalence" which may be called
                    833:   many times. Probs is memory consuming and must be used with
                    834:   parcimony.
                    835:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    836: 
                    837:   Revision 1.83  2003/06/10 13:39:11  lievre
                    838:   *** empty log message ***
                    839: 
                    840:   Revision 1.82  2003/06/05 15:57:20  brouard
                    841:   Add log in  imach.c and  fullversion number is now printed.
                    842: 
                    843: */
                    844: /*
                    845:    Interpolated Markov Chain
                    846: 
                    847:   Short summary of the programme:
                    848:   
1.227     brouard   849:   This program computes Healthy Life Expectancies or State-specific
                    850:   (if states aren't health statuses) Expectancies from
                    851:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    852: 
                    853:   -1- a first survey ("cross") where individuals from different ages
                    854:   are interviewed on their health status or degree of disability (in
                    855:   the case of a health survey which is our main interest)
                    856: 
                    857:   -2- at least a second wave of interviews ("longitudinal") which
                    858:   measure each change (if any) in individual health status.  Health
                    859:   expectancies are computed from the time spent in each health state
                    860:   according to a model. More health states you consider, more time is
                    861:   necessary to reach the Maximum Likelihood of the parameters involved
                    862:   in the model.  The simplest model is the multinomial logistic model
                    863:   where pij is the probability to be observed in state j at the second
                    864:   wave conditional to be observed in state i at the first
                    865:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    866:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    867:   have a more complex model than "constant and age", you should modify
                    868:   the program where the markup *Covariates have to be included here
                    869:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   870:   convergence.
                    871: 
                    872:   The advantage of this computer programme, compared to a simple
                    873:   multinomial logistic model, is clear when the delay between waves is not
                    874:   identical for each individual. Also, if a individual missed an
                    875:   intermediate interview, the information is lost, but taken into
                    876:   account using an interpolation or extrapolation.  
                    877: 
                    878:   hPijx is the probability to be observed in state i at age x+h
                    879:   conditional to the observed state i at age x. The delay 'h' can be
                    880:   split into an exact number (nh*stepm) of unobserved intermediate
                    881:   states. This elementary transition (by month, quarter,
                    882:   semester or year) is modelled as a multinomial logistic.  The hPx
                    883:   matrix is simply the matrix product of nh*stepm elementary matrices
                    884:   and the contribution of each individual to the likelihood is simply
                    885:   hPijx.
                    886: 
                    887:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   888:   of the life expectancies. It also computes the period (stable) prevalence.
                    889: 
                    890: Back prevalence and projections:
1.227     brouard   891: 
                    892:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    893:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    894:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    895:    mobilavproj)
                    896: 
                    897:     Computes the back prevalence limit for any combination of
                    898:     covariate values k at any age between ageminpar and agemaxpar and
                    899:     returns it in **bprlim. In the loops,
                    900: 
                    901:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    902:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    903: 
                    904:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   905:    Computes for any combination of covariates k and any age between bage and fage 
                    906:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    907:                        oldm=oldms;savm=savms;
1.227     brouard   908: 
1.267     brouard   909:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   910:      Computes the transition matrix starting at age 'age' over
                    911:      'nhstepm*hstepm*stepm' months (i.e. until
                    912:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   913:      nhstepm*hstepm matrices. 
                    914: 
                    915:      Returns p3mat[i][j][h] after calling
                    916:      p3mat[i][j][h]=matprod2(newm,
                    917:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    918:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    919:      oldm);
1.226     brouard   920: 
                    921: Important routines
                    922: 
                    923: - func (or funcone), computes logit (pij) distinguishing
                    924:   o fixed variables (single or product dummies or quantitative);
                    925:   o varying variables by:
                    926:    (1) wave (single, product dummies, quantitative), 
                    927:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    928:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    929:        % varying dummy (not done) or quantitative (not done);
                    930: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    931:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    932: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    933:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    934:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   935: 
1.226     brouard   936: 
                    937:   
1.133     brouard   938:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    939:            Institut national d'études démographiques, Paris.
1.126     brouard   940:   This software have been partly granted by Euro-REVES, a concerted action
                    941:   from the European Union.
                    942:   It is copyrighted identically to a GNU software product, ie programme and
                    943:   software can be distributed freely for non commercial use. Latest version
                    944:   can be accessed at http://euroreves.ined.fr/imach .
                    945: 
                    946:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    947:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    948:   
                    949:   **********************************************************************/
                    950: /*
                    951:   main
                    952:   read parameterfile
                    953:   read datafile
                    954:   concatwav
                    955:   freqsummary
                    956:   if (mle >= 1)
                    957:     mlikeli
                    958:   print results files
                    959:   if mle==1 
                    960:      computes hessian
                    961:   read end of parameter file: agemin, agemax, bage, fage, estepm
                    962:       begin-prev-date,...
                    963:   open gnuplot file
                    964:   open html file
1.145     brouard   965:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                    966:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                    967:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                    968:     freexexit2 possible for memory heap.
                    969: 
                    970:   h Pij x                         | pij_nom  ficrestpij
                    971:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                    972:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                    973:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                    974: 
                    975:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                    976:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                    977:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                    978:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                    979:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                    980: 
1.126     brouard   981:   forecasting if prevfcast==1 prevforecast call prevalence()
                    982:   health expectancies
                    983:   Variance-covariance of DFLE
                    984:   prevalence()
                    985:    movingaverage()
                    986:   varevsij() 
                    987:   if popbased==1 varevsij(,popbased)
                    988:   total life expectancies
                    989:   Variance of period (stable) prevalence
                    990:  end
                    991: */
                    992: 
1.187     brouard   993: /* #define DEBUG */
                    994: /* #define DEBUGBRENT */
1.203     brouard   995: /* #define DEBUGLINMIN */
                    996: /* #define DEBUGHESS */
                    997: #define DEBUGHESSIJ
1.224     brouard   998: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard   999: #define POWELL /* Instead of NLOPT */
1.224     brouard  1000: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard  1001: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                   1002: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard  1003: 
                   1004: #include <math.h>
                   1005: #include <stdio.h>
                   1006: #include <stdlib.h>
                   1007: #include <string.h>
1.226     brouard  1008: #include <ctype.h>
1.159     brouard  1009: 
                   1010: #ifdef _WIN32
                   1011: #include <io.h>
1.172     brouard  1012: #include <windows.h>
                   1013: #include <tchar.h>
1.159     brouard  1014: #else
1.126     brouard  1015: #include <unistd.h>
1.159     brouard  1016: #endif
1.126     brouard  1017: 
                   1018: #include <limits.h>
                   1019: #include <sys/types.h>
1.171     brouard  1020: 
                   1021: #if defined(__GNUC__)
                   1022: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1023: #endif
                   1024: 
1.126     brouard  1025: #include <sys/stat.h>
                   1026: #include <errno.h>
1.159     brouard  1027: /* extern int errno; */
1.126     brouard  1028: 
1.157     brouard  1029: /* #ifdef LINUX */
                   1030: /* #include <time.h> */
                   1031: /* #include "timeval.h" */
                   1032: /* #else */
                   1033: /* #include <sys/time.h> */
                   1034: /* #endif */
                   1035: 
1.126     brouard  1036: #include <time.h>
                   1037: 
1.136     brouard  1038: #ifdef GSL
                   1039: #include <gsl/gsl_errno.h>
                   1040: #include <gsl/gsl_multimin.h>
                   1041: #endif
                   1042: 
1.167     brouard  1043: 
1.162     brouard  1044: #ifdef NLOPT
                   1045: #include <nlopt.h>
                   1046: typedef struct {
                   1047:   double (* function)(double [] );
                   1048: } myfunc_data ;
                   1049: #endif
                   1050: 
1.126     brouard  1051: /* #include <libintl.h> */
                   1052: /* #define _(String) gettext (String) */
                   1053: 
1.251     brouard  1054: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1055: 
                   1056: #define GNUPLOTPROGRAM "gnuplot"
                   1057: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1058: #define FILENAMELENGTH 132
                   1059: 
                   1060: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1061: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1062: 
1.144     brouard  1063: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1064: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1065: 
                   1066: #define NINTERVMAX 8
1.144     brouard  1067: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1068: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.291     brouard  1069: #define NCOVMAX 20  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1070: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1071: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1072: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1073: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1074: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1075: /* #define AGESUP 130 */
1.288     brouard  1076: /* #define AGESUP 150 */
                   1077: #define AGESUP 200
1.268     brouard  1078: #define AGEINF 0
1.218     brouard  1079: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1080: #define AGEBASE 40
1.194     brouard  1081: #define AGEOVERFLOW 1.e20
1.164     brouard  1082: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1083: #ifdef _WIN32
                   1084: #define DIRSEPARATOR '\\'
                   1085: #define CHARSEPARATOR "\\"
                   1086: #define ODIRSEPARATOR '/'
                   1087: #else
1.126     brouard  1088: #define DIRSEPARATOR '/'
                   1089: #define CHARSEPARATOR "/"
                   1090: #define ODIRSEPARATOR '\\'
                   1091: #endif
                   1092: 
1.295   ! brouard  1093: /* $Id: imach.c,v 1.294 2019/05/16 14:54:33 brouard Exp $ */
1.126     brouard  1094: /* $State: Exp $ */
1.196     brouard  1095: #include "version.h"
                   1096: char version[]=__IMACH_VERSION__;
1.283     brouard  1097: char copyright[]="April 2018,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2018";
1.295   ! brouard  1098: char fullversion[]="$Revision: 1.294 $ $Date: 2019/05/16 14:54:33 $"; 
1.126     brouard  1099: char strstart[80];
                   1100: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1101: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1102: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1103: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1104: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1105: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1106: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1107: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1108: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1109: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1110: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1111: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1112: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1113: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1114: int nsd=0; /**< Total number of single dummy variables (output) */
                   1115: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1116: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1117: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1118: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1119: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1120: int cptcov=0; /* Working variable */
1.290     brouard  1121: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1122: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.126     brouard  1123: int npar=NPARMAX;
                   1124: int nlstate=2; /* Number of live states */
                   1125: int ndeath=1; /* Number of dead states */
1.130     brouard  1126: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1127: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1128: int popbased=0;
                   1129: 
                   1130: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1131: int maxwav=0; /* Maxim number of waves */
                   1132: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1133: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1134: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1135:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1136: int mle=1, weightopt=0;
1.126     brouard  1137: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1138: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1139: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1140:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1141: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1142: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1143: 
1.130     brouard  1144: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1145: double **matprod2(); /* test */
1.126     brouard  1146: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1147: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1148: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1149: 
1.136     brouard  1150: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1151: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1152: FILE *ficlog, *ficrespow;
1.130     brouard  1153: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1154: double fretone; /* Only one call to likelihood */
1.130     brouard  1155: long ipmx=0; /* Number of contributions */
1.126     brouard  1156: double sw; /* Sum of weights */
                   1157: char filerespow[FILENAMELENGTH];
                   1158: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1159: FILE *ficresilk;
                   1160: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1161: FILE *ficresprobmorprev;
                   1162: FILE *fichtm, *fichtmcov; /* Html File */
                   1163: FILE *ficreseij;
                   1164: char filerese[FILENAMELENGTH];
                   1165: FILE *ficresstdeij;
                   1166: char fileresstde[FILENAMELENGTH];
                   1167: FILE *ficrescveij;
                   1168: char filerescve[FILENAMELENGTH];
                   1169: FILE  *ficresvij;
                   1170: char fileresv[FILENAMELENGTH];
1.269     brouard  1171: 
1.126     brouard  1172: char title[MAXLINE];
1.234     brouard  1173: char model[MAXLINE]; /**< The model line */
1.217     brouard  1174: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1175: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1176: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1177: char command[FILENAMELENGTH];
                   1178: int  outcmd=0;
                   1179: 
1.217     brouard  1180: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1181: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1182: char filelog[FILENAMELENGTH]; /* Log file */
                   1183: char filerest[FILENAMELENGTH];
                   1184: char fileregp[FILENAMELENGTH];
                   1185: char popfile[FILENAMELENGTH];
                   1186: 
                   1187: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1188: 
1.157     brouard  1189: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1190: /* struct timezone tzp; */
                   1191: /* extern int gettimeofday(); */
                   1192: struct tm tml, *gmtime(), *localtime();
                   1193: 
                   1194: extern time_t time();
                   1195: 
                   1196: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1197: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1198: struct tm tm;
                   1199: 
1.126     brouard  1200: char strcurr[80], strfor[80];
                   1201: 
                   1202: char *endptr;
                   1203: long lval;
                   1204: double dval;
                   1205: 
                   1206: #define NR_END 1
                   1207: #define FREE_ARG char*
                   1208: #define FTOL 1.0e-10
                   1209: 
                   1210: #define NRANSI 
1.240     brouard  1211: #define ITMAX 200
                   1212: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1213: 
                   1214: #define TOL 2.0e-4 
                   1215: 
                   1216: #define CGOLD 0.3819660 
                   1217: #define ZEPS 1.0e-10 
                   1218: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1219: 
                   1220: #define GOLD 1.618034 
                   1221: #define GLIMIT 100.0 
                   1222: #define TINY 1.0e-20 
                   1223: 
                   1224: static double maxarg1,maxarg2;
                   1225: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1226: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1227:   
                   1228: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1229: #define rint(a) floor(a+0.5)
1.166     brouard  1230: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1231: #define mytinydouble 1.0e-16
1.166     brouard  1232: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1233: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1234: /* static double dsqrarg; */
                   1235: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1236: static double sqrarg;
                   1237: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1238: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1239: int agegomp= AGEGOMP;
                   1240: 
                   1241: int imx; 
                   1242: int stepm=1;
                   1243: /* Stepm, step in month: minimum step interpolation*/
                   1244: 
                   1245: int estepm;
                   1246: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1247: 
                   1248: int m,nb;
                   1249: long *num;
1.197     brouard  1250: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1251: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1252:                   covariate for which somebody answered excluding 
                   1253:                   undefined. Usually 2: 0 and 1. */
                   1254: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1255:                             covariate for which somebody answered including 
                   1256:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1257: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1258: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1259: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1260: double *ageexmed,*agecens;
                   1261: double dateintmean=0;
                   1262: 
                   1263: double *weight;
                   1264: int **s; /* Status */
1.141     brouard  1265: double *agedc;
1.145     brouard  1266: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1267:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1268:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1269: double **coqvar; /* Fixed quantitative covariate nqv */
                   1270: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1271: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1272: double  idx; 
                   1273: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1274: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1275: /*k          1  2   3   4     5    6    7     8    9 */
                   1276: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1277: /* Tndvar[k]    1   2   3               4          5 */
                   1278: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1279: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1280: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1281: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1282: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1283: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1284: /* Tprod[i]=k           4               7            */
                   1285: /* Tage[i]=k                  5               8      */
                   1286: /* */
                   1287: /* Type                    */
                   1288: /* V         1  2  3  4  5 */
                   1289: /*           F  F  V  V  V */
                   1290: /*           D  Q  D  D  Q */
                   1291: /*                         */
                   1292: int *TvarsD;
                   1293: int *TvarsDind;
                   1294: int *TvarsQ;
                   1295: int *TvarsQind;
                   1296: 
1.235     brouard  1297: #define MAXRESULTLINES 10
                   1298: int nresult=0;
1.258     brouard  1299: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1300: int TKresult[MAXRESULTLINES];
1.237     brouard  1301: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1302: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1303: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1304: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1305: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1306: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1307: 
1.234     brouard  1308: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1309: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1310: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1311: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1312: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1313: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1314: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1315: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1316: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1317: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1318: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1319: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1320: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1321: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1322: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1323: 
1.230     brouard  1324: int *Tvarsel; /**< Selected covariates for output */
                   1325: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1326: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1327: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1328: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1329: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1330: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1331: int *Tage;
1.227     brouard  1332: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1333: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1334: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1335: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1336: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1337: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1338: int **Tvard;
                   1339: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1340: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1341: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1342:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1343:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1344: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1345: double *lsurv, *lpop, *tpop;
                   1346: 
1.231     brouard  1347: #define FD 1; /* Fixed dummy covariate */
                   1348: #define FQ 2; /* Fixed quantitative covariate */
                   1349: #define FP 3; /* Fixed product covariate */
                   1350: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1351: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1352: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1353: #define VD 10; /* Varying dummy covariate */
                   1354: #define VQ 11; /* Varying quantitative covariate */
                   1355: #define VP 12; /* Varying product covariate */
                   1356: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1357: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1358: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1359: #define APFD 16; /* Age product * fixed dummy covariate */
                   1360: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1361: #define APVD 18; /* Age product * varying dummy covariate */
                   1362: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1363: 
                   1364: #define FTYPE 1; /* Fixed covariate */
                   1365: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1366: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1367: 
                   1368: struct kmodel{
                   1369:        int maintype; /* main type */
                   1370:        int subtype; /* subtype */
                   1371: };
                   1372: struct kmodel modell[NCOVMAX];
                   1373: 
1.143     brouard  1374: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1375: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1376: 
                   1377: /**************** split *************************/
                   1378: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1379: {
                   1380:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1381:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1382:   */ 
                   1383:   char *ss;                            /* pointer */
1.186     brouard  1384:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1385: 
                   1386:   l1 = strlen(path );                  /* length of path */
                   1387:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1388:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1389:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1390:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1391:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1392:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1393:     /* get current working directory */
                   1394:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1395: #ifdef WIN32
                   1396:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1397: #else
                   1398:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1399: #endif
1.126     brouard  1400:       return( GLOCK_ERROR_GETCWD );
                   1401:     }
                   1402:     /* got dirc from getcwd*/
                   1403:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1404:   } else {                             /* strip directory from path */
1.126     brouard  1405:     ss++;                              /* after this, the filename */
                   1406:     l2 = strlen( ss );                 /* length of filename */
                   1407:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1408:     strcpy( name, ss );                /* save file name */
                   1409:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1410:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1411:     printf(" DIRC2 = %s \n",dirc);
                   1412:   }
                   1413:   /* We add a separator at the end of dirc if not exists */
                   1414:   l1 = strlen( dirc );                 /* length of directory */
                   1415:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1416:     dirc[l1] =  DIRSEPARATOR;
                   1417:     dirc[l1+1] = 0; 
                   1418:     printf(" DIRC3 = %s \n",dirc);
                   1419:   }
                   1420:   ss = strrchr( name, '.' );           /* find last / */
                   1421:   if (ss >0){
                   1422:     ss++;
                   1423:     strcpy(ext,ss);                    /* save extension */
                   1424:     l1= strlen( name);
                   1425:     l2= strlen(ss)+1;
                   1426:     strncpy( finame, name, l1-l2);
                   1427:     finame[l1-l2]= 0;
                   1428:   }
                   1429: 
                   1430:   return( 0 );                         /* we're done */
                   1431: }
                   1432: 
                   1433: 
                   1434: /******************************************/
                   1435: 
                   1436: void replace_back_to_slash(char *s, char*t)
                   1437: {
                   1438:   int i;
                   1439:   int lg=0;
                   1440:   i=0;
                   1441:   lg=strlen(t);
                   1442:   for(i=0; i<= lg; i++) {
                   1443:     (s[i] = t[i]);
                   1444:     if (t[i]== '\\') s[i]='/';
                   1445:   }
                   1446: }
                   1447: 
1.132     brouard  1448: char *trimbb(char *out, char *in)
1.137     brouard  1449: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1450:   char *s;
                   1451:   s=out;
                   1452:   while (*in != '\0'){
1.137     brouard  1453:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1454:       in++;
                   1455:     }
                   1456:     *out++ = *in++;
                   1457:   }
                   1458:   *out='\0';
                   1459:   return s;
                   1460: }
                   1461: 
1.187     brouard  1462: /* char *substrchaine(char *out, char *in, char *chain) */
                   1463: /* { */
                   1464: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1465: /*   char *s, *t; */
                   1466: /*   t=in;s=out; */
                   1467: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1468: /*     *out++ = *in++; */
                   1469: /*   } */
                   1470: 
                   1471: /*   /\* *in matches *chain *\/ */
                   1472: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1473: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1474: /*   } */
                   1475: /*   in--; chain--; */
                   1476: /*   while ( (*in != '\0')){ */
                   1477: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1478: /*     *out++ = *in++; */
                   1479: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1480: /*   } */
                   1481: /*   *out='\0'; */
                   1482: /*   out=s; */
                   1483: /*   return out; */
                   1484: /* } */
                   1485: char *substrchaine(char *out, char *in, char *chain)
                   1486: {
                   1487:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1488:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1489: 
                   1490:   char *strloc;
                   1491: 
                   1492:   strcpy (out, in); 
                   1493:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1494:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1495:   if(strloc != NULL){ 
                   1496:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1497:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1498:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1499:   }
                   1500:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1501:   return out;
                   1502: }
                   1503: 
                   1504: 
1.145     brouard  1505: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1506: {
1.187     brouard  1507:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1508:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1509:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1510:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1511:   */
1.160     brouard  1512:   char *s, *t;
1.145     brouard  1513:   t=in;s=in;
                   1514:   while ((*in != occ) && (*in != '\0')){
                   1515:     *alocc++ = *in++;
                   1516:   }
                   1517:   if( *in == occ){
                   1518:     *(alocc)='\0';
                   1519:     s=++in;
                   1520:   }
                   1521:  
                   1522:   if (s == t) {/* occ not found */
                   1523:     *(alocc-(in-s))='\0';
                   1524:     in=s;
                   1525:   }
                   1526:   while ( *in != '\0'){
                   1527:     *blocc++ = *in++;
                   1528:   }
                   1529: 
                   1530:   *blocc='\0';
                   1531:   return t;
                   1532: }
1.137     brouard  1533: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1534: {
1.187     brouard  1535:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1536:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1537:      gives blocc="abcdef2ghi" and alocc="j".
                   1538:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1539:   */
                   1540:   char *s, *t;
                   1541:   t=in;s=in;
                   1542:   while (*in != '\0'){
                   1543:     while( *in == occ){
                   1544:       *blocc++ = *in++;
                   1545:       s=in;
                   1546:     }
                   1547:     *blocc++ = *in++;
                   1548:   }
                   1549:   if (s == t) /* occ not found */
                   1550:     *(blocc-(in-s))='\0';
                   1551:   else
                   1552:     *(blocc-(in-s)-1)='\0';
                   1553:   in=s;
                   1554:   while ( *in != '\0'){
                   1555:     *alocc++ = *in++;
                   1556:   }
                   1557: 
                   1558:   *alocc='\0';
                   1559:   return s;
                   1560: }
                   1561: 
1.126     brouard  1562: int nbocc(char *s, char occ)
                   1563: {
                   1564:   int i,j=0;
                   1565:   int lg=20;
                   1566:   i=0;
                   1567:   lg=strlen(s);
                   1568:   for(i=0; i<= lg; i++) {
1.234     brouard  1569:     if  (s[i] == occ ) j++;
1.126     brouard  1570:   }
                   1571:   return j;
                   1572: }
                   1573: 
1.137     brouard  1574: /* void cutv(char *u,char *v, char*t, char occ) */
                   1575: /* { */
                   1576: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1577: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1578: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1579: /*   int i,lg,j,p=0; */
                   1580: /*   i=0; */
                   1581: /*   lg=strlen(t); */
                   1582: /*   for(j=0; j<=lg-1; j++) { */
                   1583: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1584: /*   } */
1.126     brouard  1585: 
1.137     brouard  1586: /*   for(j=0; j<p; j++) { */
                   1587: /*     (u[j] = t[j]); */
                   1588: /*   } */
                   1589: /*      u[p]='\0'; */
1.126     brouard  1590: 
1.137     brouard  1591: /*    for(j=0; j<= lg; j++) { */
                   1592: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1593: /*   } */
                   1594: /* } */
1.126     brouard  1595: 
1.160     brouard  1596: #ifdef _WIN32
                   1597: char * strsep(char **pp, const char *delim)
                   1598: {
                   1599:   char *p, *q;
                   1600:          
                   1601:   if ((p = *pp) == NULL)
                   1602:     return 0;
                   1603:   if ((q = strpbrk (p, delim)) != NULL)
                   1604:   {
                   1605:     *pp = q + 1;
                   1606:     *q = '\0';
                   1607:   }
                   1608:   else
                   1609:     *pp = 0;
                   1610:   return p;
                   1611: }
                   1612: #endif
                   1613: 
1.126     brouard  1614: /********************** nrerror ********************/
                   1615: 
                   1616: void nrerror(char error_text[])
                   1617: {
                   1618:   fprintf(stderr,"ERREUR ...\n");
                   1619:   fprintf(stderr,"%s\n",error_text);
                   1620:   exit(EXIT_FAILURE);
                   1621: }
                   1622: /*********************** vector *******************/
                   1623: double *vector(int nl, int nh)
                   1624: {
                   1625:   double *v;
                   1626:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1627:   if (!v) nrerror("allocation failure in vector");
                   1628:   return v-nl+NR_END;
                   1629: }
                   1630: 
                   1631: /************************ free vector ******************/
                   1632: void free_vector(double*v, int nl, int nh)
                   1633: {
                   1634:   free((FREE_ARG)(v+nl-NR_END));
                   1635: }
                   1636: 
                   1637: /************************ivector *******************************/
                   1638: int *ivector(long nl,long nh)
                   1639: {
                   1640:   int *v;
                   1641:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1642:   if (!v) nrerror("allocation failure in ivector");
                   1643:   return v-nl+NR_END;
                   1644: }
                   1645: 
                   1646: /******************free ivector **************************/
                   1647: void free_ivector(int *v, long nl, long nh)
                   1648: {
                   1649:   free((FREE_ARG)(v+nl-NR_END));
                   1650: }
                   1651: 
                   1652: /************************lvector *******************************/
                   1653: long *lvector(long nl,long nh)
                   1654: {
                   1655:   long *v;
                   1656:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1657:   if (!v) nrerror("allocation failure in ivector");
                   1658:   return v-nl+NR_END;
                   1659: }
                   1660: 
                   1661: /******************free lvector **************************/
                   1662: void free_lvector(long *v, long nl, long nh)
                   1663: {
                   1664:   free((FREE_ARG)(v+nl-NR_END));
                   1665: }
                   1666: 
                   1667: /******************* imatrix *******************************/
                   1668: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1669:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1670: { 
                   1671:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1672:   int **m; 
                   1673:   
                   1674:   /* allocate pointers to rows */ 
                   1675:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1676:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1677:   m += NR_END; 
                   1678:   m -= nrl; 
                   1679:   
                   1680:   
                   1681:   /* allocate rows and set pointers to them */ 
                   1682:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1683:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1684:   m[nrl] += NR_END; 
                   1685:   m[nrl] -= ncl; 
                   1686:   
                   1687:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1688:   
                   1689:   /* return pointer to array of pointers to rows */ 
                   1690:   return m; 
                   1691: } 
                   1692: 
                   1693: /****************** free_imatrix *************************/
                   1694: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1695:       int **m;
                   1696:       long nch,ncl,nrh,nrl; 
                   1697:      /* free an int matrix allocated by imatrix() */ 
                   1698: { 
                   1699:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1700:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1701: } 
                   1702: 
                   1703: /******************* matrix *******************************/
                   1704: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1705: {
                   1706:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1707:   double **m;
                   1708: 
                   1709:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1710:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1711:   m += NR_END;
                   1712:   m -= nrl;
                   1713: 
                   1714:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1715:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1716:   m[nrl] += NR_END;
                   1717:   m[nrl] -= ncl;
                   1718: 
                   1719:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1720:   return m;
1.145     brouard  1721:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1722: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1723: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1724:    */
                   1725: }
                   1726: 
                   1727: /*************************free matrix ************************/
                   1728: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1729: {
                   1730:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1731:   free((FREE_ARG)(m+nrl-NR_END));
                   1732: }
                   1733: 
                   1734: /******************* ma3x *******************************/
                   1735: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1736: {
                   1737:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1738:   double ***m;
                   1739: 
                   1740:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1741:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1742:   m += NR_END;
                   1743:   m -= nrl;
                   1744: 
                   1745:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1746:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1747:   m[nrl] += NR_END;
                   1748:   m[nrl] -= ncl;
                   1749: 
                   1750:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1751: 
                   1752:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1753:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1754:   m[nrl][ncl] += NR_END;
                   1755:   m[nrl][ncl] -= nll;
                   1756:   for (j=ncl+1; j<=nch; j++) 
                   1757:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1758:   
                   1759:   for (i=nrl+1; i<=nrh; i++) {
                   1760:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1761:     for (j=ncl+1; j<=nch; j++) 
                   1762:       m[i][j]=m[i][j-1]+nlay;
                   1763:   }
                   1764:   return m; 
                   1765:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1766:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1767:   */
                   1768: }
                   1769: 
                   1770: /*************************free ma3x ************************/
                   1771: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1772: {
                   1773:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1774:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1775:   free((FREE_ARG)(m+nrl-NR_END));
                   1776: }
                   1777: 
                   1778: /*************** function subdirf ***********/
                   1779: char *subdirf(char fileres[])
                   1780: {
                   1781:   /* Caution optionfilefiname is hidden */
                   1782:   strcpy(tmpout,optionfilefiname);
                   1783:   strcat(tmpout,"/"); /* Add to the right */
                   1784:   strcat(tmpout,fileres);
                   1785:   return tmpout;
                   1786: }
                   1787: 
                   1788: /*************** function subdirf2 ***********/
                   1789: char *subdirf2(char fileres[], char *preop)
                   1790: {
                   1791:   
                   1792:   /* Caution optionfilefiname is hidden */
                   1793:   strcpy(tmpout,optionfilefiname);
                   1794:   strcat(tmpout,"/");
                   1795:   strcat(tmpout,preop);
                   1796:   strcat(tmpout,fileres);
                   1797:   return tmpout;
                   1798: }
                   1799: 
                   1800: /*************** function subdirf3 ***********/
                   1801: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1802: {
                   1803:   
                   1804:   /* Caution optionfilefiname is hidden */
                   1805:   strcpy(tmpout,optionfilefiname);
                   1806:   strcat(tmpout,"/");
                   1807:   strcat(tmpout,preop);
                   1808:   strcat(tmpout,preop2);
                   1809:   strcat(tmpout,fileres);
                   1810:   return tmpout;
                   1811: }
1.213     brouard  1812:  
                   1813: /*************** function subdirfext ***********/
                   1814: char *subdirfext(char fileres[], char *preop, char *postop)
                   1815: {
                   1816:   
                   1817:   strcpy(tmpout,preop);
                   1818:   strcat(tmpout,fileres);
                   1819:   strcat(tmpout,postop);
                   1820:   return tmpout;
                   1821: }
1.126     brouard  1822: 
1.213     brouard  1823: /*************** function subdirfext3 ***********/
                   1824: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1825: {
                   1826:   
                   1827:   /* Caution optionfilefiname is hidden */
                   1828:   strcpy(tmpout,optionfilefiname);
                   1829:   strcat(tmpout,"/");
                   1830:   strcat(tmpout,preop);
                   1831:   strcat(tmpout,fileres);
                   1832:   strcat(tmpout,postop);
                   1833:   return tmpout;
                   1834: }
                   1835:  
1.162     brouard  1836: char *asc_diff_time(long time_sec, char ascdiff[])
                   1837: {
                   1838:   long sec_left, days, hours, minutes;
                   1839:   days = (time_sec) / (60*60*24);
                   1840:   sec_left = (time_sec) % (60*60*24);
                   1841:   hours = (sec_left) / (60*60) ;
                   1842:   sec_left = (sec_left) %(60*60);
                   1843:   minutes = (sec_left) /60;
                   1844:   sec_left = (sec_left) % (60);
                   1845:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1846:   return ascdiff;
                   1847: }
                   1848: 
1.126     brouard  1849: /***************** f1dim *************************/
                   1850: extern int ncom; 
                   1851: extern double *pcom,*xicom;
                   1852: extern double (*nrfunc)(double []); 
                   1853:  
                   1854: double f1dim(double x) 
                   1855: { 
                   1856:   int j; 
                   1857:   double f;
                   1858:   double *xt; 
                   1859:  
                   1860:   xt=vector(1,ncom); 
                   1861:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1862:   f=(*nrfunc)(xt); 
                   1863:   free_vector(xt,1,ncom); 
                   1864:   return f; 
                   1865: } 
                   1866: 
                   1867: /*****************brent *************************/
                   1868: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1869: {
                   1870:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1871:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1872:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1873:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1874:    * returned function value. 
                   1875:   */
1.126     brouard  1876:   int iter; 
                   1877:   double a,b,d,etemp;
1.159     brouard  1878:   double fu=0,fv,fw,fx;
1.164     brouard  1879:   double ftemp=0.;
1.126     brouard  1880:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1881:   double e=0.0; 
                   1882:  
                   1883:   a=(ax < cx ? ax : cx); 
                   1884:   b=(ax > cx ? ax : cx); 
                   1885:   x=w=v=bx; 
                   1886:   fw=fv=fx=(*f)(x); 
                   1887:   for (iter=1;iter<=ITMAX;iter++) { 
                   1888:     xm=0.5*(a+b); 
                   1889:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1890:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1891:     printf(".");fflush(stdout);
                   1892:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1893: #ifdef DEBUGBRENT
1.126     brouard  1894:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1895:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1896:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1897: #endif
                   1898:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1899:       *xmin=x; 
                   1900:       return fx; 
                   1901:     } 
                   1902:     ftemp=fu;
                   1903:     if (fabs(e) > tol1) { 
                   1904:       r=(x-w)*(fx-fv); 
                   1905:       q=(x-v)*(fx-fw); 
                   1906:       p=(x-v)*q-(x-w)*r; 
                   1907:       q=2.0*(q-r); 
                   1908:       if (q > 0.0) p = -p; 
                   1909:       q=fabs(q); 
                   1910:       etemp=e; 
                   1911:       e=d; 
                   1912:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1913:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1914:       else { 
1.224     brouard  1915:                                d=p/q; 
                   1916:                                u=x+d; 
                   1917:                                if (u-a < tol2 || b-u < tol2) 
                   1918:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1919:       } 
                   1920:     } else { 
                   1921:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1922:     } 
                   1923:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1924:     fu=(*f)(u); 
                   1925:     if (fu <= fx) { 
                   1926:       if (u >= x) a=x; else b=x; 
                   1927:       SHFT(v,w,x,u) 
1.183     brouard  1928:       SHFT(fv,fw,fx,fu) 
                   1929:     } else { 
                   1930:       if (u < x) a=u; else b=u; 
                   1931:       if (fu <= fw || w == x) { 
1.224     brouard  1932:                                v=w; 
                   1933:                                w=u; 
                   1934:                                fv=fw; 
                   1935:                                fw=fu; 
1.183     brouard  1936:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1937:                                v=u; 
                   1938:                                fv=fu; 
1.183     brouard  1939:       } 
                   1940:     } 
1.126     brouard  1941:   } 
                   1942:   nrerror("Too many iterations in brent"); 
                   1943:   *xmin=x; 
                   1944:   return fx; 
                   1945: } 
                   1946: 
                   1947: /****************** mnbrak ***********************/
                   1948: 
                   1949: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1950:            double (*func)(double)) 
1.183     brouard  1951: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1952: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1953: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1954: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1955:    */
1.126     brouard  1956:   double ulim,u,r,q, dum;
                   1957:   double fu; 
1.187     brouard  1958: 
                   1959:   double scale=10.;
                   1960:   int iterscale=0;
                   1961: 
                   1962:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   1963:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   1964: 
                   1965: 
                   1966:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   1967:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   1968:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   1969:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   1970:   /* } */
                   1971: 
1.126     brouard  1972:   if (*fb > *fa) { 
                   1973:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  1974:     SHFT(dum,*fb,*fa,dum) 
                   1975:   } 
1.126     brouard  1976:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   1977:   *fc=(*func)(*cx); 
1.183     brouard  1978: #ifdef DEBUG
1.224     brouard  1979:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   1980:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  1981: #endif
1.224     brouard  1982:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  1983:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  1984:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  1985:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  1986:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   1987:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   1988:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  1989:       fu=(*func)(u); 
1.163     brouard  1990: #ifdef DEBUG
                   1991:       /* f(x)=A(x-u)**2+f(u) */
                   1992:       double A, fparabu; 
                   1993:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   1994:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  1995:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   1996:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  1997:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   1998:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   1999:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   2000:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  2001: #endif 
1.184     brouard  2002: #ifdef MNBRAKORIGINAL
1.183     brouard  2003: #else
1.191     brouard  2004: /*       if (fu > *fc) { */
                   2005: /* #ifdef DEBUG */
                   2006: /*       printf("mnbrak4  fu > fc \n"); */
                   2007: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   2008: /* #endif */
                   2009: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2010: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2011: /*     dum=u; /\* Shifting c and u *\/ */
                   2012: /*     u = *cx; */
                   2013: /*     *cx = dum; */
                   2014: /*     dum = fu; */
                   2015: /*     fu = *fc; */
                   2016: /*     *fc =dum; */
                   2017: /*       } else { /\* end *\/ */
                   2018: /* #ifdef DEBUG */
                   2019: /*       printf("mnbrak3  fu < fc \n"); */
                   2020: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2021: /* #endif */
                   2022: /*     dum=u; /\* Shifting c and u *\/ */
                   2023: /*     u = *cx; */
                   2024: /*     *cx = dum; */
                   2025: /*     dum = fu; */
                   2026: /*     fu = *fc; */
                   2027: /*     *fc =dum; */
                   2028: /*       } */
1.224     brouard  2029: #ifdef DEBUGMNBRAK
                   2030:                 double A, fparabu; 
                   2031:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2032:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2033:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2034:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2035: #endif
1.191     brouard  2036:       dum=u; /* Shifting c and u */
                   2037:       u = *cx;
                   2038:       *cx = dum;
                   2039:       dum = fu;
                   2040:       fu = *fc;
                   2041:       *fc =dum;
1.183     brouard  2042: #endif
1.162     brouard  2043:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2044: #ifdef DEBUG
1.224     brouard  2045:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2046:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2047: #endif
1.126     brouard  2048:       fu=(*func)(u); 
                   2049:       if (fu < *fc) { 
1.183     brouard  2050: #ifdef DEBUG
1.224     brouard  2051:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2052:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2053: #endif
                   2054:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2055:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2056: #ifdef DEBUG
                   2057:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2058: #endif
                   2059:       } 
1.162     brouard  2060:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2061: #ifdef DEBUG
1.224     brouard  2062:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2063:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2064: #endif
1.126     brouard  2065:       u=ulim; 
                   2066:       fu=(*func)(u); 
1.183     brouard  2067:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2068: #ifdef DEBUG
1.224     brouard  2069:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2070:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2071: #endif
1.126     brouard  2072:       u=(*cx)+GOLD*(*cx-*bx); 
                   2073:       fu=(*func)(u); 
1.224     brouard  2074: #ifdef DEBUG
                   2075:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2076:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2077: #endif
1.183     brouard  2078:     } /* end tests */
1.126     brouard  2079:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2080:     SHFT(*fa,*fb,*fc,fu) 
                   2081: #ifdef DEBUG
1.224     brouard  2082:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2083:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2084: #endif
                   2085:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2086: } 
                   2087: 
                   2088: /*************** linmin ************************/
1.162     brouard  2089: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2090: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2091: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2092: the value of func at the returned location p . This is actually all accomplished by calling the
                   2093: routines mnbrak and brent .*/
1.126     brouard  2094: int ncom; 
                   2095: double *pcom,*xicom;
                   2096: double (*nrfunc)(double []); 
                   2097:  
1.224     brouard  2098: #ifdef LINMINORIGINAL
1.126     brouard  2099: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2100: #else
                   2101: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2102: #endif
1.126     brouard  2103: { 
                   2104:   double brent(double ax, double bx, double cx, 
                   2105:               double (*f)(double), double tol, double *xmin); 
                   2106:   double f1dim(double x); 
                   2107:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2108:              double *fc, double (*func)(double)); 
                   2109:   int j; 
                   2110:   double xx,xmin,bx,ax; 
                   2111:   double fx,fb,fa;
1.187     brouard  2112: 
1.203     brouard  2113: #ifdef LINMINORIGINAL
                   2114: #else
                   2115:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2116: #endif
                   2117:   
1.126     brouard  2118:   ncom=n; 
                   2119:   pcom=vector(1,n); 
                   2120:   xicom=vector(1,n); 
                   2121:   nrfunc=func; 
                   2122:   for (j=1;j<=n;j++) { 
                   2123:     pcom[j]=p[j]; 
1.202     brouard  2124:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2125:   } 
1.187     brouard  2126: 
1.203     brouard  2127: #ifdef LINMINORIGINAL
                   2128:   xx=1.;
                   2129: #else
                   2130:   axs=0.0;
                   2131:   xxs=1.;
                   2132:   do{
                   2133:     xx= xxs;
                   2134: #endif
1.187     brouard  2135:     ax=0.;
                   2136:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2137:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2138:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2139:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2140:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2141:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2142:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2143: #ifdef LINMINORIGINAL
                   2144: #else
                   2145:     if (fx != fx){
1.224     brouard  2146:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2147:                        printf("|");
                   2148:                        fprintf(ficlog,"|");
1.203     brouard  2149: #ifdef DEBUGLINMIN
1.224     brouard  2150:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2151: #endif
                   2152:     }
1.224     brouard  2153:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2154: #endif
                   2155:   
1.191     brouard  2156: #ifdef DEBUGLINMIN
                   2157:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2158:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2159: #endif
1.224     brouard  2160: #ifdef LINMINORIGINAL
                   2161: #else
                   2162:        if(fb == fx){ /* Flat function in the direction */
                   2163:                xmin=xx;
                   2164:     *flat=1;
                   2165:        }else{
                   2166:     *flat=0;
                   2167: #endif
                   2168:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2169:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2170:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2171:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2172:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2173:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2174: #ifdef DEBUG
1.224     brouard  2175:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2176:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2177: #endif
                   2178: #ifdef LINMINORIGINAL
                   2179: #else
                   2180:                        }
1.126     brouard  2181: #endif
1.191     brouard  2182: #ifdef DEBUGLINMIN
                   2183:   printf("linmin end ");
1.202     brouard  2184:   fprintf(ficlog,"linmin end ");
1.191     brouard  2185: #endif
1.126     brouard  2186:   for (j=1;j<=n;j++) { 
1.203     brouard  2187: #ifdef LINMINORIGINAL
                   2188:     xi[j] *= xmin; 
                   2189: #else
                   2190: #ifdef DEBUGLINMIN
                   2191:     if(xxs <1.0)
                   2192:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2193: #endif
                   2194:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2195: #ifdef DEBUGLINMIN
                   2196:     if(xxs <1.0)
                   2197:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2198: #endif
                   2199: #endif
1.187     brouard  2200:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2201:   } 
1.191     brouard  2202: #ifdef DEBUGLINMIN
1.203     brouard  2203:   printf("\n");
1.191     brouard  2204:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2205:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2206:   for (j=1;j<=n;j++) { 
1.202     brouard  2207:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2208:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2209:     if(j % ncovmodel == 0){
1.191     brouard  2210:       printf("\n");
1.202     brouard  2211:       fprintf(ficlog,"\n");
                   2212:     }
1.191     brouard  2213:   }
1.203     brouard  2214: #else
1.191     brouard  2215: #endif
1.126     brouard  2216:   free_vector(xicom,1,n); 
                   2217:   free_vector(pcom,1,n); 
                   2218: } 
                   2219: 
                   2220: 
                   2221: /*************** powell ************************/
1.162     brouard  2222: /*
                   2223: Minimization of a function func of n variables. Input consists of an initial starting point
                   2224: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2225: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2226: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2227: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2228: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2229:  */
1.224     brouard  2230: #ifdef LINMINORIGINAL
                   2231: #else
                   2232:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2233:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2234: #endif
1.126     brouard  2235: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2236:            double (*func)(double [])) 
                   2237: { 
1.224     brouard  2238: #ifdef LINMINORIGINAL
                   2239:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2240:              double (*func)(double [])); 
1.224     brouard  2241: #else 
1.241     brouard  2242:  void linmin(double p[], double xi[], int n, double *fret,
                   2243:             double (*func)(double []),int *flat); 
1.224     brouard  2244: #endif
1.239     brouard  2245:  int i,ibig,j,jk,k; 
1.126     brouard  2246:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2247:   double directest;
1.126     brouard  2248:   double fp,fptt;
                   2249:   double *xits;
                   2250:   int niterf, itmp;
1.224     brouard  2251: #ifdef LINMINORIGINAL
                   2252: #else
                   2253: 
                   2254:   flatdir=ivector(1,n); 
                   2255:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2256: #endif
1.126     brouard  2257: 
                   2258:   pt=vector(1,n); 
                   2259:   ptt=vector(1,n); 
                   2260:   xit=vector(1,n); 
                   2261:   xits=vector(1,n); 
                   2262:   *fret=(*func)(p); 
                   2263:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2264:   rcurr_time = time(NULL);  
1.126     brouard  2265:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2266:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2267:     ibig=0; 
                   2268:     del=0.0; 
1.157     brouard  2269:     rlast_time=rcurr_time;
                   2270:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2271:     rcurr_time = time(NULL);  
                   2272:     curr_time = *localtime(&rcurr_time);
                   2273:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2274:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2275: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2276:     for (i=1;i<=n;i++) {
1.126     brouard  2277:       fprintf(ficrespow," %.12lf", p[i]);
                   2278:     }
1.239     brouard  2279:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2280:     printf("\n#model=  1      +     age ");
                   2281:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2282:     if(nagesqr==1){
1.241     brouard  2283:        printf("  + age*age  ");
                   2284:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2285:     }
                   2286:     for(j=1;j <=ncovmodel-2;j++){
                   2287:       if(Typevar[j]==0) {
                   2288:        printf("  +      V%d  ",Tvar[j]);
                   2289:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2290:       }else if(Typevar[j]==1) {
                   2291:        printf("  +    V%d*age ",Tvar[j]);
                   2292:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2293:       }else if(Typevar[j]==2) {
                   2294:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2295:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2296:       }
                   2297:     }
1.126     brouard  2298:     printf("\n");
1.239     brouard  2299: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2300: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2301:     fprintf(ficlog,"\n");
1.239     brouard  2302:     for(i=1,jk=1; i <=nlstate; i++){
                   2303:       for(k=1; k <=(nlstate+ndeath); k++){
                   2304:        if (k != i) {
                   2305:          printf("%d%d ",i,k);
                   2306:          fprintf(ficlog,"%d%d ",i,k);
                   2307:          for(j=1; j <=ncovmodel; j++){
                   2308:            printf("%12.7f ",p[jk]);
                   2309:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2310:            jk++; 
                   2311:          }
                   2312:          printf("\n");
                   2313:          fprintf(ficlog,"\n");
                   2314:        }
                   2315:       }
                   2316:     }
1.241     brouard  2317:     if(*iter <=3 && *iter >1){
1.157     brouard  2318:       tml = *localtime(&rcurr_time);
                   2319:       strcpy(strcurr,asctime(&tml));
                   2320:       rforecast_time=rcurr_time; 
1.126     brouard  2321:       itmp = strlen(strcurr);
                   2322:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2323:        strcurr[itmp-1]='\0';
1.162     brouard  2324:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2325:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2326:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2327:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2328:        forecast_time = *localtime(&rforecast_time);
                   2329:        strcpy(strfor,asctime(&forecast_time));
                   2330:        itmp = strlen(strfor);
                   2331:        if(strfor[itmp-1]=='\n')
                   2332:          strfor[itmp-1]='\0';
                   2333:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2334:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2335:       }
                   2336:     }
1.187     brouard  2337:     for (i=1;i<=n;i++) { /* For each direction i */
                   2338:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2339:       fptt=(*fret); 
                   2340: #ifdef DEBUG
1.203     brouard  2341:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2342:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2343: #endif
1.203     brouard  2344:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2345:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2346: #ifdef LINMINORIGINAL
1.188     brouard  2347:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2348: #else
                   2349:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2350:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2351: #endif
                   2352:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2353:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2354:                                /* because that direction will be replaced unless the gain del is small */
                   2355:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2356:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2357:                                /* with the new direction. */
                   2358:                                del=fabs(fptt-(*fret)); 
                   2359:                                ibig=i; 
1.126     brouard  2360:       } 
                   2361: #ifdef DEBUG
                   2362:       printf("%d %.12e",i,(*fret));
                   2363:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2364:       for (j=1;j<=n;j++) {
1.224     brouard  2365:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2366:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2367:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2368:       }
                   2369:       for(j=1;j<=n;j++) {
1.225     brouard  2370:                                printf(" p(%d)=%.12e",j,p[j]);
                   2371:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2372:       }
                   2373:       printf("\n");
                   2374:       fprintf(ficlog,"\n");
                   2375: #endif
1.187     brouard  2376:     } /* end loop on each direction i */
                   2377:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2378:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2379:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2380:       for(j=1;j<=n;j++) {
1.225     brouard  2381:                                if(flatdir[j] >0){
                   2382:                                        printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2383:                                        fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2384:                                }
                   2385:                                /* printf("\n"); */
                   2386:                                /* fprintf(ficlog,"\n"); */
                   2387:                        }
1.243     brouard  2388:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2389:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2390:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2391:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2392:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2393:       /* decreased of more than 3.84  */
                   2394:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2395:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2396:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2397:                        
1.188     brouard  2398:       /* Starting the program with initial values given by a former maximization will simply change */
                   2399:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2400:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2401:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2402: #ifdef DEBUG
                   2403:       int k[2],l;
                   2404:       k[0]=1;
                   2405:       k[1]=-1;
                   2406:       printf("Max: %.12e",(*func)(p));
                   2407:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2408:       for (j=1;j<=n;j++) {
                   2409:        printf(" %.12e",p[j]);
                   2410:        fprintf(ficlog," %.12e",p[j]);
                   2411:       }
                   2412:       printf("\n");
                   2413:       fprintf(ficlog,"\n");
                   2414:       for(l=0;l<=1;l++) {
                   2415:        for (j=1;j<=n;j++) {
                   2416:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2417:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2418:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2419:        }
                   2420:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2421:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2422:       }
                   2423: #endif
                   2424: 
1.224     brouard  2425: #ifdef LINMINORIGINAL
                   2426: #else
                   2427:       free_ivector(flatdir,1,n); 
                   2428: #endif
1.126     brouard  2429:       free_vector(xit,1,n); 
                   2430:       free_vector(xits,1,n); 
                   2431:       free_vector(ptt,1,n); 
                   2432:       free_vector(pt,1,n); 
                   2433:       return; 
1.192     brouard  2434:     } /* enough precision */ 
1.240     brouard  2435:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2436:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2437:       ptt[j]=2.0*p[j]-pt[j]; 
                   2438:       xit[j]=p[j]-pt[j]; 
                   2439:       pt[j]=p[j]; 
                   2440:     } 
1.181     brouard  2441:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2442: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2443:                if (*iter <=4) {
1.225     brouard  2444: #else
                   2445: #endif
1.224     brouard  2446: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2447: #else
1.161     brouard  2448:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2449: #endif
1.162     brouard  2450:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2451:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2452:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2453:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2454:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2455:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2456:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2457:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2458:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2459:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2460:       /* mu² and del² are equal when f3=f1 */
                   2461:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2462:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2463:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2464:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2465: #ifdef NRCORIGINAL
                   2466:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2467: #else
                   2468:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2469:       t= t- del*SQR(fp-fptt);
1.183     brouard  2470: #endif
1.202     brouard  2471:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2472: #ifdef DEBUG
1.181     brouard  2473:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2474:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2475:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2476:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2477:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2478:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2479:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2480:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2481: #endif
1.183     brouard  2482: #ifdef POWELLORIGINAL
                   2483:       if (t < 0.0) { /* Then we use it for new direction */
                   2484: #else
1.182     brouard  2485:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2486:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2487:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2488:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2489:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2490:       } 
1.181     brouard  2491:       if (directest < 0.0) { /* Then we use it for new direction */
                   2492: #endif
1.191     brouard  2493: #ifdef DEBUGLINMIN
1.234     brouard  2494:        printf("Before linmin in direction P%d-P0\n",n);
                   2495:        for (j=1;j<=n;j++) {
                   2496:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2497:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2498:          if(j % ncovmodel == 0){
                   2499:            printf("\n");
                   2500:            fprintf(ficlog,"\n");
                   2501:          }
                   2502:        }
1.224     brouard  2503: #endif
                   2504: #ifdef LINMINORIGINAL
1.234     brouard  2505:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2506: #else
1.234     brouard  2507:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2508:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2509: #endif
1.234     brouard  2510:        
1.191     brouard  2511: #ifdef DEBUGLINMIN
1.234     brouard  2512:        for (j=1;j<=n;j++) { 
                   2513:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2514:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2515:          if(j % ncovmodel == 0){
                   2516:            printf("\n");
                   2517:            fprintf(ficlog,"\n");
                   2518:          }
                   2519:        }
1.224     brouard  2520: #endif
1.234     brouard  2521:        for (j=1;j<=n;j++) { 
                   2522:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2523:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2524:        }
1.224     brouard  2525: #ifdef LINMINORIGINAL
                   2526: #else
1.234     brouard  2527:        for (j=1, flatd=0;j<=n;j++) {
                   2528:          if(flatdir[j]>0)
                   2529:            flatd++;
                   2530:        }
                   2531:        if(flatd >0){
1.255     brouard  2532:          printf("%d flat directions: ",flatd);
                   2533:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2534:          for (j=1;j<=n;j++) { 
                   2535:            if(flatdir[j]>0){
                   2536:              printf("%d ",j);
                   2537:              fprintf(ficlog,"%d ",j);
                   2538:            }
                   2539:          }
                   2540:          printf("\n");
                   2541:          fprintf(ficlog,"\n");
                   2542:        }
1.191     brouard  2543: #endif
1.234     brouard  2544:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2545:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2546:        
1.126     brouard  2547: #ifdef DEBUG
1.234     brouard  2548:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2549:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2550:        for(j=1;j<=n;j++){
                   2551:          printf(" %lf",xit[j]);
                   2552:          fprintf(ficlog," %lf",xit[j]);
                   2553:        }
                   2554:        printf("\n");
                   2555:        fprintf(ficlog,"\n");
1.126     brouard  2556: #endif
1.192     brouard  2557:       } /* end of t or directest negative */
1.224     brouard  2558: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2559: #else
1.234     brouard  2560:       } /* end if (fptt < fp)  */
1.192     brouard  2561: #endif
1.225     brouard  2562: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2563:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2564: #else
1.224     brouard  2565: #endif
1.234     brouard  2566:                } /* loop iteration */ 
1.126     brouard  2567: } 
1.234     brouard  2568:   
1.126     brouard  2569: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2570:   
1.235     brouard  2571:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2572:   {
1.279     brouard  2573:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2574:      *   (and selected quantitative values in nres)
                   2575:      *  by left multiplying the unit
                   2576:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2577:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2578:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2579:      * or prevalence in state 1, prevalence in state 2, 0
                   2580:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2581:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2582:      * Output is prlim.
                   2583:      * Initial matrix pimij 
                   2584:      */
1.206     brouard  2585:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2586:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2587:   /*  0,                   0                  , 1} */
                   2588:   /*
                   2589:    * and after some iteration: */
                   2590:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2591:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2592:   /*  0,                   0                  , 1} */
                   2593:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2594:   /* {0.51571254859325999, 0.4842874514067399, */
                   2595:   /*  0.51326036147820708, 0.48673963852179264} */
                   2596:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2597:     
1.126     brouard  2598:   int i, ii,j,k;
1.209     brouard  2599:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2600:   /* double **matprod2(); */ /* test */
1.218     brouard  2601:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2602:   double **newm;
1.209     brouard  2603:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2604:   int ncvloop=0;
1.288     brouard  2605:   int first=0;
1.169     brouard  2606:   
1.209     brouard  2607:   min=vector(1,nlstate);
                   2608:   max=vector(1,nlstate);
                   2609:   meandiff=vector(1,nlstate);
                   2610: 
1.218     brouard  2611:        /* Starting with matrix unity */
1.126     brouard  2612:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2613:     for (j=1;j<=nlstate+ndeath;j++){
                   2614:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2615:     }
1.169     brouard  2616:   
                   2617:   cov[1]=1.;
                   2618:   
                   2619:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2620:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2621:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2622:     ncvloop++;
1.126     brouard  2623:     newm=savm;
                   2624:     /* Covariates have to be included here again */
1.138     brouard  2625:     cov[2]=agefin;
1.187     brouard  2626:     if(nagesqr==1)
                   2627:       cov[3]= agefin*agefin;;
1.234     brouard  2628:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2629:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2630:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2631:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2632:     }
                   2633:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2634:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2635:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2636:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2637:     }
1.237     brouard  2638:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2639:       if(Dummy[Tvar[Tage[k]]]){
                   2640:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2641:       } else{
1.235     brouard  2642:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2643:       }
1.235     brouard  2644:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2645:     }
1.237     brouard  2646:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2647:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2648:       if(Dummy[Tvard[k][1]==0]){
                   2649:        if(Dummy[Tvard[k][2]==0]){
                   2650:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2651:        }else{
                   2652:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2653:        }
                   2654:       }else{
                   2655:        if(Dummy[Tvard[k][2]==0]){
                   2656:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2657:        }else{
                   2658:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2659:        }
                   2660:       }
1.234     brouard  2661:     }
1.138     brouard  2662:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2663:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2664:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2665:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2666:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2667:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2668:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2669:     
1.126     brouard  2670:     savm=oldm;
                   2671:     oldm=newm;
1.209     brouard  2672: 
                   2673:     for(j=1; j<=nlstate; j++){
                   2674:       max[j]=0.;
                   2675:       min[j]=1.;
                   2676:     }
                   2677:     for(i=1;i<=nlstate;i++){
                   2678:       sumnew=0;
                   2679:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2680:       for(j=1; j<=nlstate; j++){ 
                   2681:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2682:        max[j]=FMAX(max[j],prlim[i][j]);
                   2683:        min[j]=FMIN(min[j],prlim[i][j]);
                   2684:       }
                   2685:     }
                   2686: 
1.126     brouard  2687:     maxmax=0.;
1.209     brouard  2688:     for(j=1; j<=nlstate; j++){
                   2689:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2690:       maxmax=FMAX(maxmax,meandiff[j]);
                   2691:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2692:     } /* j loop */
1.203     brouard  2693:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2694:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2695:     if(maxmax < ftolpl){
1.209     brouard  2696:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2697:       free_vector(min,1,nlstate);
                   2698:       free_vector(max,1,nlstate);
                   2699:       free_vector(meandiff,1,nlstate);
1.126     brouard  2700:       return prlim;
                   2701:     }
1.288     brouard  2702:   } /* agefin loop */
1.208     brouard  2703:     /* After some age loop it doesn't converge */
1.288     brouard  2704:   if(!first){
                   2705:     first=1;
                   2706:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2707:   }
                   2708:   fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2709: 
1.209     brouard  2710:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2711:   free_vector(min,1,nlstate);
                   2712:   free_vector(max,1,nlstate);
                   2713:   free_vector(meandiff,1,nlstate);
1.208     brouard  2714:   
1.169     brouard  2715:   return prlim; /* should not reach here */
1.126     brouard  2716: }
                   2717: 
1.217     brouard  2718: 
                   2719:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2720: 
1.218     brouard  2721:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2722:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2723:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2724: {
1.264     brouard  2725:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2726:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2727:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2728:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2729:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2730:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2731:   /* Initial matrix pimij */
                   2732:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2733:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2734:   /*  0,                   0                  , 1} */
                   2735:   /*
                   2736:    * and after some iteration: */
                   2737:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2738:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2739:   /*  0,                   0                  , 1} */
                   2740:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2741:   /* {0.51571254859325999, 0.4842874514067399, */
                   2742:   /*  0.51326036147820708, 0.48673963852179264} */
                   2743:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2744: 
                   2745:   int i, ii,j,k;
1.247     brouard  2746:   int first=0;
1.217     brouard  2747:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2748:   /* double **matprod2(); */ /* test */
                   2749:   double **out, cov[NCOVMAX+1], **bmij();
                   2750:   double **newm;
1.218     brouard  2751:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2752:   double        **oldm, **savm;  /* for use */
                   2753: 
1.217     brouard  2754:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2755:   int ncvloop=0;
                   2756:   
                   2757:   min=vector(1,nlstate);
                   2758:   max=vector(1,nlstate);
                   2759:   meandiff=vector(1,nlstate);
                   2760: 
1.266     brouard  2761:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2762:   oldm=oldms; savm=savms;
                   2763:   
                   2764:   /* Starting with matrix unity */
                   2765:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2766:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2767:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2768:     }
                   2769:   
                   2770:   cov[1]=1.;
                   2771:   
                   2772:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2773:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2774:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2775:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2776:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2777:     ncvloop++;
1.218     brouard  2778:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2779:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2780:     /* Covariates have to be included here again */
                   2781:     cov[2]=agefin;
                   2782:     if(nagesqr==1)
                   2783:       cov[3]= agefin*agefin;;
1.242     brouard  2784:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2785:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2786:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2787:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2788:     }
                   2789:     /* for (k=1; k<=cptcovn;k++) { */
                   2790:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2791:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2792:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2793:     /* } */
                   2794:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2795:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2796:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2797:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2798:     }
                   2799:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2800:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2801:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2802:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2803:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2804:       if(Dummy[Tvar[Tage[k]]]){
                   2805:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2806:       } else{
                   2807:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2808:       }
                   2809:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2810:     }
                   2811:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2812:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2813:       if(Dummy[Tvard[k][1]==0]){
                   2814:        if(Dummy[Tvard[k][2]==0]){
                   2815:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2816:        }else{
                   2817:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2818:        }
                   2819:       }else{
                   2820:        if(Dummy[Tvard[k][2]==0]){
                   2821:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2822:        }else{
                   2823:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2824:        }
                   2825:       }
1.217     brouard  2826:     }
                   2827:     
                   2828:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2829:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2830:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2831:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2832:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2833:                /* ij should be linked to the correct index of cov */
                   2834:                /* age and covariate values ij are in 'cov', but we need to pass
                   2835:                 * ij for the observed prevalence at age and status and covariate
                   2836:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2837:                 */
                   2838:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2839:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2840:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2841:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2842:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2843:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2844:     /*         printf("%d newm= ",i); */
                   2845:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2846:     /*           printf("%f ",newm[i][j]); */
                   2847:     /*         } */
                   2848:     /*         printf("oldm * "); */
                   2849:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2850:     /*           printf("%f ",oldm[i][j]); */
                   2851:     /*         } */
1.268     brouard  2852:     /*         printf(" bmmij "); */
1.266     brouard  2853:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2854:     /*           printf("%f ",pmmij[i][j]); */
                   2855:     /*         } */
                   2856:     /*         printf("\n"); */
                   2857:     /*   } */
                   2858:     /* } */
1.217     brouard  2859:     savm=oldm;
                   2860:     oldm=newm;
1.266     brouard  2861: 
1.217     brouard  2862:     for(j=1; j<=nlstate; j++){
                   2863:       max[j]=0.;
                   2864:       min[j]=1.;
                   2865:     }
                   2866:     for(j=1; j<=nlstate; j++){ 
                   2867:       for(i=1;i<=nlstate;i++){
1.234     brouard  2868:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2869:        bprlim[i][j]= newm[i][j];
                   2870:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2871:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2872:       }
                   2873:     }
1.218     brouard  2874:                
1.217     brouard  2875:     maxmax=0.;
                   2876:     for(i=1; i<=nlstate; i++){
                   2877:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2878:       maxmax=FMAX(maxmax,meandiff[i]);
                   2879:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2880:     } /* i loop */
1.217     brouard  2881:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2882:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2883:     if(maxmax < ftolpl){
1.220     brouard  2884:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2885:       free_vector(min,1,nlstate);
                   2886:       free_vector(max,1,nlstate);
                   2887:       free_vector(meandiff,1,nlstate);
                   2888:       return bprlim;
                   2889:     }
1.288     brouard  2890:   } /* agefin loop */
1.217     brouard  2891:     /* After some age loop it doesn't converge */
1.288     brouard  2892:   if(!first){
1.247     brouard  2893:     first=1;
                   2894:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2895: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2896:   }
                   2897:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2898: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2899:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2900:   free_vector(min,1,nlstate);
                   2901:   free_vector(max,1,nlstate);
                   2902:   free_vector(meandiff,1,nlstate);
                   2903:   
                   2904:   return bprlim; /* should not reach here */
                   2905: }
                   2906: 
1.126     brouard  2907: /*************** transition probabilities ***************/ 
                   2908: 
                   2909: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2910: {
1.138     brouard  2911:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2912:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2913:      model to the ncovmodel covariates (including constant and age).
                   2914:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2915:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2916:      ncth covariate in the global vector x is given by the formula:
                   2917:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2918:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2919:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2920:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2921:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2922:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2923:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2924:   */
                   2925:   double s1, lnpijopii;
1.126     brouard  2926:   /*double t34;*/
1.164     brouard  2927:   int i,j, nc, ii, jj;
1.126     brouard  2928: 
1.223     brouard  2929:   for(i=1; i<= nlstate; i++){
                   2930:     for(j=1; j<i;j++){
                   2931:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2932:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2933:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2934:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2935:       }
                   2936:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2937:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2938:     }
                   2939:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2940:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2941:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2942:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2943:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2944:       }
                   2945:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2946:     }
                   2947:   }
1.218     brouard  2948:   
1.223     brouard  2949:   for(i=1; i<= nlstate; i++){
                   2950:     s1=0;
                   2951:     for(j=1; j<i; j++){
                   2952:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2953:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2954:     }
                   2955:     for(j=i+1; j<=nlstate+ndeath; j++){
                   2956:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2957:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2958:     }
                   2959:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   2960:     ps[i][i]=1./(s1+1.);
                   2961:     /* Computing other pijs */
                   2962:     for(j=1; j<i; j++)
                   2963:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2964:     for(j=i+1; j<=nlstate+ndeath; j++)
                   2965:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   2966:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   2967:   } /* end i */
1.218     brouard  2968:   
1.223     brouard  2969:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   2970:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   2971:       ps[ii][jj]=0;
                   2972:       ps[ii][ii]=1;
                   2973:     }
                   2974:   }
1.294     brouard  2975: 
                   2976: 
1.223     brouard  2977:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   2978:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   2979:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   2980:   /*   } */
                   2981:   /*   printf("\n "); */
                   2982:   /* } */
                   2983:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   2984:   /*
                   2985:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  2986:                goto end;*/
1.266     brouard  2987:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  2988: }
                   2989: 
1.218     brouard  2990: /*************** backward transition probabilities ***************/ 
                   2991: 
                   2992:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2993: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   2994:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   2995: {
1.266     brouard  2996:   /* Computes the backward probability at age agefin and covariate combination ij. In fact cov is already filled and x too.
                   2997:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  2998:    */
1.218     brouard  2999:   int i, ii, j,k;
1.222     brouard  3000:   
                   3001:   double **out, **pmij();
                   3002:   double sumnew=0.;
1.218     brouard  3003:   double agefin;
1.292     brouard  3004:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  3005:   double **dnewm, **dsavm, **doldm;
                   3006:   double **bbmij;
                   3007:   
1.218     brouard  3008:   doldm=ddoldms; /* global pointers */
1.222     brouard  3009:   dnewm=ddnewms;
                   3010:   dsavm=ddsavms;
                   3011:   
                   3012:   agefin=cov[2];
1.268     brouard  3013:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3014:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3015:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3016:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3017: 
                   3018:   /* P_x */
1.266     brouard  3019:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3020:   /* outputs pmmij which is a stochastic matrix in row */
                   3021: 
                   3022:   /* Diag(w_x) */
1.292     brouard  3023:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3024:   sumnew=0.;
1.269     brouard  3025:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3026:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.269     brouard  3027:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]);  */
1.268     brouard  3028:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3029:   }
                   3030:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3031:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3032:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3033:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3034:     }
                   3035:   }else{
                   3036:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3037:       for (j=1;j<=nlstate+ndeath;j++)
                   3038:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3039:     }
                   3040:     /* if(sumnew <0.9){ */
                   3041:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3042:     /* } */
                   3043:   }
                   3044:   k3=0.0;  /* We put the last diagonal to 0 */
                   3045:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3046:       doldm[ii][ii]= k3;
                   3047:   }
                   3048:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3049:   
1.292     brouard  3050:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
                   3051:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3052: 
1.292     brouard  3053:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3054:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3055:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3056:     sumnew=0.;
1.222     brouard  3057:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3058:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3059:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3060:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3061:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3062:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3063:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3064:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3065:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3066:        /* }else */
1.268     brouard  3067:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3068:     } /*End ii */
                   3069:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3070: 
1.292     brouard  3071:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3072:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3073:   /* end bmij */
1.266     brouard  3074:   return ps; /*pointer is unchanged */
1.218     brouard  3075: }
1.217     brouard  3076: /*************** transition probabilities ***************/ 
                   3077: 
1.218     brouard  3078: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3079: {
                   3080:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3081:      computes the probability to be observed in state j being in state i by appying the
                   3082:      model to the ncovmodel covariates (including constant and age).
                   3083:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3084:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3085:      ncth covariate in the global vector x is given by the formula:
                   3086:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3087:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3088:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3089:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3090:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3091:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3092:   */
                   3093:   double s1, lnpijopii;
                   3094:   /*double t34;*/
                   3095:   int i,j, nc, ii, jj;
                   3096: 
1.234     brouard  3097:   for(i=1; i<= nlstate; i++){
                   3098:     for(j=1; j<i;j++){
                   3099:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3100:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3101:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3102:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3103:       }
                   3104:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3105:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3106:     }
                   3107:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3108:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3109:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3110:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3111:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3112:       }
                   3113:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3114:     }
                   3115:   }
                   3116:   
                   3117:   for(i=1; i<= nlstate; i++){
                   3118:     s1=0;
                   3119:     for(j=1; j<i; j++){
                   3120:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3121:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3122:     }
                   3123:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3124:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3125:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3126:     }
                   3127:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3128:     ps[i][i]=1./(s1+1.);
                   3129:     /* Computing other pijs */
                   3130:     for(j=1; j<i; j++)
                   3131:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3132:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3133:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3134:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3135:   } /* end i */
                   3136:   
                   3137:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3138:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3139:       ps[ii][jj]=0;
                   3140:       ps[ii][ii]=1;
                   3141:     }
                   3142:   }
                   3143:   /* Added for backcast */ /* Transposed matrix too */
                   3144:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3145:     s1=0.;
                   3146:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3147:       s1+=ps[ii][jj];
                   3148:     }
                   3149:     for(ii=1; ii<= nlstate; ii++){
                   3150:       ps[ii][jj]=ps[ii][jj]/s1;
                   3151:     }
                   3152:   }
                   3153:   /* Transposition */
                   3154:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3155:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3156:       s1=ps[ii][jj];
                   3157:       ps[ii][jj]=ps[jj][ii];
                   3158:       ps[jj][ii]=s1;
                   3159:     }
                   3160:   }
                   3161:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3162:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3163:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3164:   /*   } */
                   3165:   /*   printf("\n "); */
                   3166:   /* } */
                   3167:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3168:   /*
                   3169:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3170:     goto end;*/
                   3171:   return ps;
1.217     brouard  3172: }
                   3173: 
                   3174: 
1.126     brouard  3175: /**************** Product of 2 matrices ******************/
                   3176: 
1.145     brouard  3177: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3178: {
                   3179:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3180:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3181:   /* in, b, out are matrice of pointers which should have been initialized 
                   3182:      before: only the contents of out is modified. The function returns
                   3183:      a pointer to pointers identical to out */
1.145     brouard  3184:   int i, j, k;
1.126     brouard  3185:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3186:     for(k=ncolol; k<=ncoloh; k++){
                   3187:       out[i][k]=0.;
                   3188:       for(j=ncl; j<=nch; j++)
                   3189:        out[i][k] +=in[i][j]*b[j][k];
                   3190:     }
1.126     brouard  3191:   return out;
                   3192: }
                   3193: 
                   3194: 
                   3195: /************* Higher Matrix Product ***************/
                   3196: 
1.235     brouard  3197: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3198: {
1.218     brouard  3199:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3200:      'nhstepm*hstepm*stepm' months (i.e. until
                   3201:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3202:      nhstepm*hstepm matrices. 
                   3203:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3204:      (typically every 2 years instead of every month which is too big 
                   3205:      for the memory).
                   3206:      Model is determined by parameters x and covariates have to be 
                   3207:      included manually here. 
                   3208: 
                   3209:      */
                   3210: 
                   3211:   int i, j, d, h, k;
1.131     brouard  3212:   double **out, cov[NCOVMAX+1];
1.126     brouard  3213:   double **newm;
1.187     brouard  3214:   double agexact;
1.214     brouard  3215:   double agebegin, ageend;
1.126     brouard  3216: 
                   3217:   /* Hstepm could be zero and should return the unit matrix */
                   3218:   for (i=1;i<=nlstate+ndeath;i++)
                   3219:     for (j=1;j<=nlstate+ndeath;j++){
                   3220:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3221:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3222:     }
                   3223:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3224:   for(h=1; h <=nhstepm; h++){
                   3225:     for(d=1; d <=hstepm; d++){
                   3226:       newm=savm;
                   3227:       /* Covariates have to be included here again */
                   3228:       cov[1]=1.;
1.214     brouard  3229:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3230:       cov[2]=agexact;
                   3231:       if(nagesqr==1)
1.227     brouard  3232:        cov[3]= agexact*agexact;
1.235     brouard  3233:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3234:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3235:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3236:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3237:       }
                   3238:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3239:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3240:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3241:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3242:       }
                   3243:       for (k=1; k<=cptcovage;k++){
                   3244:        if(Dummy[Tvar[Tage[k]]]){
                   3245:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3246:        } else{
                   3247:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3248:        }
                   3249:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3250:       }
                   3251:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3252:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3253:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3254:       }
                   3255:       /* for (k=1; k<=cptcovn;k++)  */
                   3256:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3257:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3258:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3259:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3260:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3261:       
                   3262:       
1.126     brouard  3263:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3264:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3265:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3266:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3267:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3268:       /* if((int)age == 70){ */
                   3269:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3270:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3271:       /*         printf("%d pmmij ",i); */
                   3272:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3273:       /*           printf("%f ",pmmij[i][j]); */
                   3274:       /*         } */
                   3275:       /*         printf(" oldm "); */
                   3276:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3277:       /*           printf("%f ",oldm[i][j]); */
                   3278:       /*         } */
                   3279:       /*         printf("\n"); */
                   3280:       /*       } */
                   3281:       /* } */
1.126     brouard  3282:       savm=oldm;
                   3283:       oldm=newm;
                   3284:     }
                   3285:     for(i=1; i<=nlstate+ndeath; i++)
                   3286:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3287:        po[i][j][h]=newm[i][j];
                   3288:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3289:       }
1.128     brouard  3290:     /*printf("h=%d ",h);*/
1.126     brouard  3291:   } /* end h */
1.267     brouard  3292:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3293:   return po;
                   3294: }
                   3295: 
1.217     brouard  3296: /************* Higher Back Matrix Product ***************/
1.218     brouard  3297: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3298: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3299: {
1.266     brouard  3300:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3301:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3302:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3303:      nhstepm*hstepm matrices.
                   3304:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3305:      (typically every 2 years instead of every month which is too big
1.217     brouard  3306:      for the memory).
1.218     brouard  3307:      Model is determined by parameters x and covariates have to be
1.266     brouard  3308:      included manually here. Then we use a call to bmij(x and cov)
                   3309:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3310:   */
1.217     brouard  3311: 
                   3312:   int i, j, d, h, k;
1.266     brouard  3313:   double **out, cov[NCOVMAX+1], **bmij();
                   3314:   double **newm, ***newmm;
1.217     brouard  3315:   double agexact;
                   3316:   double agebegin, ageend;
1.222     brouard  3317:   double **oldm, **savm;
1.217     brouard  3318: 
1.266     brouard  3319:   newmm=po; /* To be saved */
                   3320:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3321:   /* Hstepm could be zero and should return the unit matrix */
                   3322:   for (i=1;i<=nlstate+ndeath;i++)
                   3323:     for (j=1;j<=nlstate+ndeath;j++){
                   3324:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3325:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3326:     }
                   3327:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3328:   for(h=1; h <=nhstepm; h++){
                   3329:     for(d=1; d <=hstepm; d++){
                   3330:       newm=savm;
                   3331:       /* Covariates have to be included here again */
                   3332:       cov[1]=1.;
1.271     brouard  3333:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3334:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3335:       cov[2]=agexact;
                   3336:       if(nagesqr==1)
1.222     brouard  3337:        cov[3]= agexact*agexact;
1.266     brouard  3338:       for (k=1; k<=cptcovn;k++){
                   3339:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3340:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3341:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3342:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3343:       }
1.267     brouard  3344:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3345:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3346:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3347:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3348:       }
                   3349:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3350:        if(Dummy[Tvar[Tage[k]]]){
                   3351:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3352:        } else{
                   3353:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3354:        }
                   3355:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3356:       }
                   3357:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3358:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3359:       }                        
1.217     brouard  3360:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3361:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3362: 
1.218     brouard  3363:       /* Careful transposed matrix */
1.266     brouard  3364:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3365:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3366:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3367:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3368:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3369:       /* if((int)age == 70){ */
                   3370:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3371:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3372:       /*         printf("%d pmmij ",i); */
                   3373:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3374:       /*           printf("%f ",pmmij[i][j]); */
                   3375:       /*         } */
                   3376:       /*         printf(" oldm "); */
                   3377:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3378:       /*           printf("%f ",oldm[i][j]); */
                   3379:       /*         } */
                   3380:       /*         printf("\n"); */
                   3381:       /*       } */
                   3382:       /* } */
                   3383:       savm=oldm;
                   3384:       oldm=newm;
                   3385:     }
                   3386:     for(i=1; i<=nlstate+ndeath; i++)
                   3387:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3388:        po[i][j][h]=newm[i][j];
1.268     brouard  3389:        /* if(h==nhstepm) */
                   3390:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3391:       }
1.268     brouard  3392:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3393:   } /* end h */
1.268     brouard  3394:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3395:   return po;
                   3396: }
                   3397: 
                   3398: 
1.162     brouard  3399: #ifdef NLOPT
                   3400:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3401:   double fret;
                   3402:   double *xt;
                   3403:   int j;
                   3404:   myfunc_data *d2 = (myfunc_data *) pd;
                   3405: /* xt = (p1-1); */
                   3406:   xt=vector(1,n); 
                   3407:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3408: 
                   3409:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3410:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3411:   printf("Function = %.12lf ",fret);
                   3412:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3413:   printf("\n");
                   3414:  free_vector(xt,1,n);
                   3415:   return fret;
                   3416: }
                   3417: #endif
1.126     brouard  3418: 
                   3419: /*************** log-likelihood *************/
                   3420: double func( double *x)
                   3421: {
1.226     brouard  3422:   int i, ii, j, k, mi, d, kk;
                   3423:   int ioffset=0;
                   3424:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3425:   double **out;
                   3426:   double lli; /* Individual log likelihood */
                   3427:   int s1, s2;
1.228     brouard  3428:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3429:   double bbh, survp;
                   3430:   long ipmx;
                   3431:   double agexact;
                   3432:   /*extern weight */
                   3433:   /* We are differentiating ll according to initial status */
                   3434:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3435:   /*for(i=1;i<imx;i++) 
                   3436:     printf(" %d\n",s[4][i]);
                   3437:   */
1.162     brouard  3438: 
1.226     brouard  3439:   ++countcallfunc;
1.162     brouard  3440: 
1.226     brouard  3441:   cov[1]=1.;
1.126     brouard  3442: 
1.226     brouard  3443:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3444:   ioffset=0;
1.226     brouard  3445:   if(mle==1){
                   3446:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3447:       /* Computes the values of the ncovmodel covariates of the model
                   3448:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3449:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3450:         to be observed in j being in i according to the model.
                   3451:       */
1.243     brouard  3452:       ioffset=2+nagesqr ;
1.233     brouard  3453:    /* Fixed */
1.234     brouard  3454:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3455:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3456:       }
1.226     brouard  3457:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3458:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3459:         has been calculated etc */
                   3460:       /* For an individual i, wav[i] gives the number of effective waves */
                   3461:       /* We compute the contribution to Likelihood of each effective transition
                   3462:         mw[mi][i] is real wave of the mi th effectve wave */
                   3463:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3464:         s2=s[mw[mi+1][i]][i];
                   3465:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3466:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3467:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3468:       */
                   3469:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3470:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3471:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3472:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3473:        }
                   3474:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3475:          for (j=1;j<=nlstate+ndeath;j++){
                   3476:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3477:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3478:          }
                   3479:        for(d=0; d<dh[mi][i]; d++){
                   3480:          newm=savm;
                   3481:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3482:          cov[2]=agexact;
                   3483:          if(nagesqr==1)
                   3484:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3485:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3486:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3487:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3488:          else
                   3489:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3490:          }
                   3491:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3492:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3493:          savm=oldm;
                   3494:          oldm=newm;
                   3495:        } /* end mult */
                   3496:        
                   3497:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3498:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3499:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3500:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3501:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3502:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3503:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3504:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3505:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3506:                                 * -stepm/2 to stepm/2 .
                   3507:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3508:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3509:                                 */
1.234     brouard  3510:        s1=s[mw[mi][i]][i];
                   3511:        s2=s[mw[mi+1][i]][i];
                   3512:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3513:        /* bias bh is positive if real duration
                   3514:         * is higher than the multiple of stepm and negative otherwise.
                   3515:         */
                   3516:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3517:        if( s2 > nlstate){ 
                   3518:          /* i.e. if s2 is a death state and if the date of death is known 
                   3519:             then the contribution to the likelihood is the probability to 
                   3520:             die between last step unit time and current  step unit time, 
                   3521:             which is also equal to probability to die before dh 
                   3522:             minus probability to die before dh-stepm . 
                   3523:             In version up to 0.92 likelihood was computed
                   3524:             as if date of death was unknown. Death was treated as any other
                   3525:             health state: the date of the interview describes the actual state
                   3526:             and not the date of a change in health state. The former idea was
                   3527:             to consider that at each interview the state was recorded
                   3528:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3529:             introduced the exact date of death then we should have modified
                   3530:             the contribution of an exact death to the likelihood. This new
                   3531:             contribution is smaller and very dependent of the step unit
                   3532:             stepm. It is no more the probability to die between last interview
                   3533:             and month of death but the probability to survive from last
                   3534:             interview up to one month before death multiplied by the
                   3535:             probability to die within a month. Thanks to Chris
                   3536:             Jackson for correcting this bug.  Former versions increased
                   3537:             mortality artificially. The bad side is that we add another loop
                   3538:             which slows down the processing. The difference can be up to 10%
                   3539:             lower mortality.
                   3540:          */
                   3541:          /* If, at the beginning of the maximization mostly, the
                   3542:             cumulative probability or probability to be dead is
                   3543:             constant (ie = 1) over time d, the difference is equal to
                   3544:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3545:             s1 at precedent wave, to be dead a month before current
                   3546:             wave is equal to probability, being at state s1 at
                   3547:             precedent wave, to be dead at mont of the current
                   3548:             wave. Then the observed probability (that this person died)
                   3549:             is null according to current estimated parameter. In fact,
                   3550:             it should be very low but not zero otherwise the log go to
                   3551:             infinity.
                   3552:          */
1.183     brouard  3553: /* #ifdef INFINITYORIGINAL */
                   3554: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3555: /* #else */
                   3556: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3557: /*         lli=log(mytinydouble); */
                   3558: /*       else */
                   3559: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3560: /* #endif */
1.226     brouard  3561:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3562:          
1.226     brouard  3563:        } else if  ( s2==-1 ) { /* alive */
                   3564:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3565:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3566:          /*survp += out[s1][j]; */
                   3567:          lli= log(survp);
                   3568:        }
                   3569:        else if  (s2==-4) { 
                   3570:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3571:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3572:          lli= log(survp); 
                   3573:        } 
                   3574:        else if  (s2==-5) { 
                   3575:          for (j=1,survp=0. ; j<=2; j++)  
                   3576:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3577:          lli= log(survp); 
                   3578:        } 
                   3579:        else{
                   3580:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3581:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3582:        } 
                   3583:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3584:        /*if(lli ==000.0)*/
                   3585:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3586:        ipmx +=1;
                   3587:        sw += weight[i];
                   3588:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3589:        /* if (lli < log(mytinydouble)){ */
                   3590:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3591:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3592:        /* } */
                   3593:       } /* end of wave */
                   3594:     } /* end of individual */
                   3595:   }  else if(mle==2){
                   3596:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3597:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3598:       for(mi=1; mi<= wav[i]-1; mi++){
                   3599:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3600:          for (j=1;j<=nlstate+ndeath;j++){
                   3601:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3602:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3603:          }
                   3604:        for(d=0; d<=dh[mi][i]; d++){
                   3605:          newm=savm;
                   3606:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3607:          cov[2]=agexact;
                   3608:          if(nagesqr==1)
                   3609:            cov[3]= agexact*agexact;
                   3610:          for (kk=1; kk<=cptcovage;kk++) {
                   3611:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3612:          }
                   3613:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3614:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3615:          savm=oldm;
                   3616:          oldm=newm;
                   3617:        } /* end mult */
                   3618:       
                   3619:        s1=s[mw[mi][i]][i];
                   3620:        s2=s[mw[mi+1][i]][i];
                   3621:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3622:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3623:        ipmx +=1;
                   3624:        sw += weight[i];
                   3625:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3626:       } /* end of wave */
                   3627:     } /* end of individual */
                   3628:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3629:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3630:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3631:       for(mi=1; mi<= wav[i]-1; mi++){
                   3632:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3633:          for (j=1;j<=nlstate+ndeath;j++){
                   3634:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3635:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3636:          }
                   3637:        for(d=0; d<dh[mi][i]; d++){
                   3638:          newm=savm;
                   3639:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3640:          cov[2]=agexact;
                   3641:          if(nagesqr==1)
                   3642:            cov[3]= agexact*agexact;
                   3643:          for (kk=1; kk<=cptcovage;kk++) {
                   3644:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3645:          }
                   3646:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3647:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3648:          savm=oldm;
                   3649:          oldm=newm;
                   3650:        } /* end mult */
                   3651:       
                   3652:        s1=s[mw[mi][i]][i];
                   3653:        s2=s[mw[mi+1][i]][i];
                   3654:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3655:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3656:        ipmx +=1;
                   3657:        sw += weight[i];
                   3658:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3659:       } /* end of wave */
                   3660:     } /* end of individual */
                   3661:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3662:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3663:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3664:       for(mi=1; mi<= wav[i]-1; mi++){
                   3665:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3666:          for (j=1;j<=nlstate+ndeath;j++){
                   3667:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3668:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3669:          }
                   3670:        for(d=0; d<dh[mi][i]; d++){
                   3671:          newm=savm;
                   3672:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3673:          cov[2]=agexact;
                   3674:          if(nagesqr==1)
                   3675:            cov[3]= agexact*agexact;
                   3676:          for (kk=1; kk<=cptcovage;kk++) {
                   3677:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3678:          }
1.126     brouard  3679:        
1.226     brouard  3680:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3681:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3682:          savm=oldm;
                   3683:          oldm=newm;
                   3684:        } /* end mult */
                   3685:       
                   3686:        s1=s[mw[mi][i]][i];
                   3687:        s2=s[mw[mi+1][i]][i];
                   3688:        if( s2 > nlstate){ 
                   3689:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3690:        } else if  ( s2==-1 ) { /* alive */
                   3691:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3692:            survp += out[s1][j];
                   3693:          lli= log(survp);
                   3694:        }else{
                   3695:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3696:        }
                   3697:        ipmx +=1;
                   3698:        sw += weight[i];
                   3699:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3700: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3701:       } /* end of wave */
                   3702:     } /* end of individual */
                   3703:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3704:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3705:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3706:       for(mi=1; mi<= wav[i]-1; mi++){
                   3707:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3708:          for (j=1;j<=nlstate+ndeath;j++){
                   3709:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3710:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3711:          }
                   3712:        for(d=0; d<dh[mi][i]; d++){
                   3713:          newm=savm;
                   3714:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3715:          cov[2]=agexact;
                   3716:          if(nagesqr==1)
                   3717:            cov[3]= agexact*agexact;
                   3718:          for (kk=1; kk<=cptcovage;kk++) {
                   3719:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3720:          }
1.126     brouard  3721:        
1.226     brouard  3722:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3723:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3724:          savm=oldm;
                   3725:          oldm=newm;
                   3726:        } /* end mult */
                   3727:       
                   3728:        s1=s[mw[mi][i]][i];
                   3729:        s2=s[mw[mi+1][i]][i];
                   3730:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3731:        ipmx +=1;
                   3732:        sw += weight[i];
                   3733:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3734:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3735:       } /* end of wave */
                   3736:     } /* end of individual */
                   3737:   } /* End of if */
                   3738:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3739:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3740:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3741:   return -l;
1.126     brouard  3742: }
                   3743: 
                   3744: /*************** log-likelihood *************/
                   3745: double funcone( double *x)
                   3746: {
1.228     brouard  3747:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3748:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3749:   int ioffset=0;
1.131     brouard  3750:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3751:   double **out;
                   3752:   double lli; /* Individual log likelihood */
                   3753:   double llt;
                   3754:   int s1, s2;
1.228     brouard  3755:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3756: 
1.126     brouard  3757:   double bbh, survp;
1.187     brouard  3758:   double agexact;
1.214     brouard  3759:   double agebegin, ageend;
1.126     brouard  3760:   /*extern weight */
                   3761:   /* We are differentiating ll according to initial status */
                   3762:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3763:   /*for(i=1;i<imx;i++) 
                   3764:     printf(" %d\n",s[4][i]);
                   3765:   */
                   3766:   cov[1]=1.;
                   3767: 
                   3768:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3769:   ioffset=0;
                   3770:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3771:     /* ioffset=2+nagesqr+cptcovage; */
                   3772:     ioffset=2+nagesqr;
1.232     brouard  3773:     /* Fixed */
1.224     brouard  3774:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3775:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3776:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3777:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3778: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3779: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3780: /*    cov[2+6]=covar[2][i]; V2  */
                   3781: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3782: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3783: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3784: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3785: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3786: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3787:     }
1.232     brouard  3788:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3789:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3790:     /* } */
1.231     brouard  3791:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3792:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3793:     /* } */
1.225     brouard  3794:     
1.233     brouard  3795: 
                   3796:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3797:     /* Wave varying (but not age varying) */
                   3798:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3799:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3800:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3801:       }
1.232     brouard  3802:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3803:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3804:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3805:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3806:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3807:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3808:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3809:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3810:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3811:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3812:       /* } */
1.126     brouard  3813:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3814:        for (j=1;j<=nlstate+ndeath;j++){
                   3815:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3816:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3817:        }
1.214     brouard  3818:       
                   3819:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3820:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3821:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3822:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3823:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3824:          and mw[mi+1][i]. dh depends on stepm.*/
                   3825:        newm=savm;
1.247     brouard  3826:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3827:        cov[2]=agexact;
                   3828:        if(nagesqr==1)
                   3829:          cov[3]= agexact*agexact;
                   3830:        for (kk=1; kk<=cptcovage;kk++) {
                   3831:          if(!FixedV[Tvar[Tage[kk]]])
                   3832:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3833:          else
                   3834:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3835:        }
                   3836:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3837:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3838:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3839:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3840:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3841:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3842:        savm=oldm;
                   3843:        oldm=newm;
1.126     brouard  3844:       } /* end mult */
                   3845:       
                   3846:       s1=s[mw[mi][i]][i];
                   3847:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3848:       /* if(s2==-1){ */
1.268     brouard  3849:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3850:       /*       /\* exit(1); *\/ */
                   3851:       /* } */
1.126     brouard  3852:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3853:       /* bias is positive if real duration
                   3854:        * is higher than the multiple of stepm and negative otherwise.
                   3855:        */
                   3856:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3857:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3858:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3859:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3860:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3861:        lli= log(survp);
1.126     brouard  3862:       }else if (mle==1){
1.242     brouard  3863:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3864:       } else if(mle==2){
1.242     brouard  3865:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3866:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3867:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3868:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3869:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3870:       } else{  /* mle=0 back to 1 */
1.242     brouard  3871:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3872:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3873:       } /* End of if */
                   3874:       ipmx +=1;
                   3875:       sw += weight[i];
                   3876:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3877:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3878:       if(globpr){
1.246     brouard  3879:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3880:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3881:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3882:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3883:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3884:          llt +=ll[k]*gipmx/gsw;
                   3885:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3886:        }
                   3887:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3888:       }
1.232     brouard  3889:        } /* end of wave */
                   3890: } /* end of individual */
                   3891: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3892: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3893: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3894: if(globpr==0){ /* First time we count the contributions and weights */
                   3895:        gipmx=ipmx;
                   3896:        gsw=sw;
                   3897: }
                   3898: return -l;
1.126     brouard  3899: }
                   3900: 
                   3901: 
                   3902: /*************** function likelione ***********/
1.292     brouard  3903: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  3904: {
                   3905:   /* This routine should help understanding what is done with 
                   3906:      the selection of individuals/waves and
                   3907:      to check the exact contribution to the likelihood.
                   3908:      Plotting could be done.
                   3909:    */
                   3910:   int k;
                   3911: 
                   3912:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3913:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3914:     strcat(fileresilk,fileresu);
1.126     brouard  3915:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3916:       printf("Problem with resultfile: %s\n", fileresilk);
                   3917:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3918:     }
1.214     brouard  3919:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3920:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3921:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3922:     for(k=1; k<=nlstate; k++) 
                   3923:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3924:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3925:   }
                   3926: 
1.292     brouard  3927:   *fretone=(*func)(p);
1.126     brouard  3928:   if(*globpri !=0){
                   3929:     fclose(ficresilk);
1.205     brouard  3930:     if (mle ==0)
                   3931:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3932:     else if(mle >=1)
                   3933:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3934:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3935:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3936:       
                   3937:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3938:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3939: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3940:     }
1.207     brouard  3941:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3942: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3943:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3944: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3945:     fflush(fichtm);
1.205     brouard  3946:   }
1.126     brouard  3947:   return;
                   3948: }
                   3949: 
                   3950: 
                   3951: /*********** Maximum Likelihood Estimation ***************/
                   3952: 
                   3953: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3954: {
1.165     brouard  3955:   int i,j, iter=0;
1.126     brouard  3956:   double **xi;
                   3957:   double fret;
                   3958:   double fretone; /* Only one call to likelihood */
                   3959:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  3960: 
                   3961: #ifdef NLOPT
                   3962:   int creturn;
                   3963:   nlopt_opt opt;
                   3964:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   3965:   double *lb;
                   3966:   double minf; /* the minimum objective value, upon return */
                   3967:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   3968:   myfunc_data dinst, *d = &dinst;
                   3969: #endif
                   3970: 
                   3971: 
1.126     brouard  3972:   xi=matrix(1,npar,1,npar);
                   3973:   for (i=1;i<=npar;i++)
                   3974:     for (j=1;j<=npar;j++)
                   3975:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   3976:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  3977:   strcpy(filerespow,"POW_"); 
1.126     brouard  3978:   strcat(filerespow,fileres);
                   3979:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   3980:     printf("Problem with resultfile: %s\n", filerespow);
                   3981:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   3982:   }
                   3983:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   3984:   for (i=1;i<=nlstate;i++)
                   3985:     for(j=1;j<=nlstate+ndeath;j++)
                   3986:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   3987:   fprintf(ficrespow,"\n");
1.162     brouard  3988: #ifdef POWELL
1.126     brouard  3989:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  3990: #endif
1.126     brouard  3991: 
1.162     brouard  3992: #ifdef NLOPT
                   3993: #ifdef NEWUOA
                   3994:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   3995: #else
                   3996:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   3997: #endif
                   3998:   lb=vector(0,npar-1);
                   3999:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   4000:   nlopt_set_lower_bounds(opt, lb);
                   4001:   nlopt_set_initial_step1(opt, 0.1);
                   4002:   
                   4003:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   4004:   d->function = func;
                   4005:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   4006:   nlopt_set_min_objective(opt, myfunc, d);
                   4007:   nlopt_set_xtol_rel(opt, ftol);
                   4008:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4009:     printf("nlopt failed! %d\n",creturn); 
                   4010:   }
                   4011:   else {
                   4012:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4013:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4014:     iter=1; /* not equal */
                   4015:   }
                   4016:   nlopt_destroy(opt);
                   4017: #endif
1.126     brouard  4018:   free_matrix(xi,1,npar,1,npar);
                   4019:   fclose(ficrespow);
1.203     brouard  4020:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4021:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4022:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4023: 
                   4024: }
                   4025: 
                   4026: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4027: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4028: {
                   4029:   double  **a,**y,*x,pd;
1.203     brouard  4030:   /* double **hess; */
1.164     brouard  4031:   int i, j;
1.126     brouard  4032:   int *indx;
                   4033: 
                   4034:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4035:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4036:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4037:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4038:   double gompertz(double p[]);
1.203     brouard  4039:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4040: 
                   4041:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4042:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4043:   for (i=1;i<=npar;i++){
1.203     brouard  4044:     printf("%d-",i);fflush(stdout);
                   4045:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4046:    
                   4047:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4048:     
                   4049:     /*  printf(" %f ",p[i]);
                   4050:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4051:   }
                   4052:   
                   4053:   for (i=1;i<=npar;i++) {
                   4054:     for (j=1;j<=npar;j++)  {
                   4055:       if (j>i) { 
1.203     brouard  4056:        printf(".%d-%d",i,j);fflush(stdout);
                   4057:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4058:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4059:        
                   4060:        hess[j][i]=hess[i][j];    
                   4061:        /*printf(" %lf ",hess[i][j]);*/
                   4062:       }
                   4063:     }
                   4064:   }
                   4065:   printf("\n");
                   4066:   fprintf(ficlog,"\n");
                   4067: 
                   4068:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4069:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4070:   
                   4071:   a=matrix(1,npar,1,npar);
                   4072:   y=matrix(1,npar,1,npar);
                   4073:   x=vector(1,npar);
                   4074:   indx=ivector(1,npar);
                   4075:   for (i=1;i<=npar;i++)
                   4076:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4077:   ludcmp(a,npar,indx,&pd);
                   4078: 
                   4079:   for (j=1;j<=npar;j++) {
                   4080:     for (i=1;i<=npar;i++) x[i]=0;
                   4081:     x[j]=1;
                   4082:     lubksb(a,npar,indx,x);
                   4083:     for (i=1;i<=npar;i++){ 
                   4084:       matcov[i][j]=x[i];
                   4085:     }
                   4086:   }
                   4087: 
                   4088:   printf("\n#Hessian matrix#\n");
                   4089:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4090:   for (i=1;i<=npar;i++) { 
                   4091:     for (j=1;j<=npar;j++) { 
1.203     brouard  4092:       printf("%.6e ",hess[i][j]);
                   4093:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4094:     }
                   4095:     printf("\n");
                   4096:     fprintf(ficlog,"\n");
                   4097:   }
                   4098: 
1.203     brouard  4099:   /* printf("\n#Covariance matrix#\n"); */
                   4100:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4101:   /* for (i=1;i<=npar;i++) {  */
                   4102:   /*   for (j=1;j<=npar;j++) {  */
                   4103:   /*     printf("%.6e ",matcov[i][j]); */
                   4104:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4105:   /*   } */
                   4106:   /*   printf("\n"); */
                   4107:   /*   fprintf(ficlog,"\n"); */
                   4108:   /* } */
                   4109: 
1.126     brouard  4110:   /* Recompute Inverse */
1.203     brouard  4111:   /* for (i=1;i<=npar;i++) */
                   4112:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4113:   /* ludcmp(a,npar,indx,&pd); */
                   4114: 
                   4115:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4116: 
                   4117:   /* for (j=1;j<=npar;j++) { */
                   4118:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4119:   /*   x[j]=1; */
                   4120:   /*   lubksb(a,npar,indx,x); */
                   4121:   /*   for (i=1;i<=npar;i++){  */
                   4122:   /*     y[i][j]=x[i]; */
                   4123:   /*     printf("%.3e ",y[i][j]); */
                   4124:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4125:   /*   } */
                   4126:   /*   printf("\n"); */
                   4127:   /*   fprintf(ficlog,"\n"); */
                   4128:   /* } */
                   4129: 
                   4130:   /* Verifying the inverse matrix */
                   4131: #ifdef DEBUGHESS
                   4132:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4133: 
1.203     brouard  4134:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4135:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4136: 
                   4137:   for (j=1;j<=npar;j++) {
                   4138:     for (i=1;i<=npar;i++){ 
1.203     brouard  4139:       printf("%.2f ",y[i][j]);
                   4140:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4141:     }
                   4142:     printf("\n");
                   4143:     fprintf(ficlog,"\n");
                   4144:   }
1.203     brouard  4145: #endif
1.126     brouard  4146: 
                   4147:   free_matrix(a,1,npar,1,npar);
                   4148:   free_matrix(y,1,npar,1,npar);
                   4149:   free_vector(x,1,npar);
                   4150:   free_ivector(indx,1,npar);
1.203     brouard  4151:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4152: 
                   4153: 
                   4154: }
                   4155: 
                   4156: /*************** hessian matrix ****************/
                   4157: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4158: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4159:   int i;
                   4160:   int l=1, lmax=20;
1.203     brouard  4161:   double k1,k2, res, fx;
1.132     brouard  4162:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4163:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4164:   int k=0,kmax=10;
                   4165:   double l1;
                   4166: 
                   4167:   fx=func(x);
                   4168:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4169:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4170:     l1=pow(10,l);
                   4171:     delts=delt;
                   4172:     for(k=1 ; k <kmax; k=k+1){
                   4173:       delt = delta*(l1*k);
                   4174:       p2[theta]=x[theta] +delt;
1.145     brouard  4175:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4176:       p2[theta]=x[theta]-delt;
                   4177:       k2=func(p2)-fx;
                   4178:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4179:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4180:       
1.203     brouard  4181: #ifdef DEBUGHESSII
1.126     brouard  4182:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4183:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4184: #endif
                   4185:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4186:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4187:        k=kmax;
                   4188:       }
                   4189:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4190:        k=kmax; l=lmax*10;
1.126     brouard  4191:       }
                   4192:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4193:        delts=delt;
                   4194:       }
1.203     brouard  4195:     } /* End loop k */
1.126     brouard  4196:   }
                   4197:   delti[theta]=delts;
                   4198:   return res; 
                   4199:   
                   4200: }
                   4201: 
1.203     brouard  4202: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4203: {
                   4204:   int i;
1.164     brouard  4205:   int l=1, lmax=20;
1.126     brouard  4206:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4207:   double p2[MAXPARM+1];
1.203     brouard  4208:   int k, kmax=1;
                   4209:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4210: 
                   4211:   int firstime=0;
1.203     brouard  4212:   
1.126     brouard  4213:   fx=func(x);
1.203     brouard  4214:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4215:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4216:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4217:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4218:     k1=func(p2)-fx;
                   4219:   
1.203     brouard  4220:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4221:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4222:     k2=func(p2)-fx;
                   4223:   
1.203     brouard  4224:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4225:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4226:     k3=func(p2)-fx;
                   4227:   
1.203     brouard  4228:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4229:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4230:     k4=func(p2)-fx;
1.203     brouard  4231:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4232:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4233:       firstime=1;
1.203     brouard  4234:       kmax=kmax+10;
1.208     brouard  4235:     }
                   4236:     if(kmax >=10 || firstime ==1){
1.246     brouard  4237:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4238:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4239:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4240:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4241:     }
                   4242: #ifdef DEBUGHESSIJ
                   4243:     v1=hess[thetai][thetai];
                   4244:     v2=hess[thetaj][thetaj];
                   4245:     cv12=res;
                   4246:     /* Computing eigen value of Hessian matrix */
                   4247:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4248:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4249:     if ((lc2 <0) || (lc1 <0) ){
                   4250:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4251:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4252:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4253:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4254:     }
1.126     brouard  4255: #endif
                   4256:   }
                   4257:   return res;
                   4258: }
                   4259: 
1.203     brouard  4260:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4261: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4262: /* { */
                   4263: /*   int i; */
                   4264: /*   int l=1, lmax=20; */
                   4265: /*   double k1,k2,k3,k4,res,fx; */
                   4266: /*   double p2[MAXPARM+1]; */
                   4267: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4268: /*   int k=0,kmax=10; */
                   4269: /*   double l1; */
                   4270:   
                   4271: /*   fx=func(x); */
                   4272: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4273: /*     l1=pow(10,l); */
                   4274: /*     delts=delt; */
                   4275: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4276: /*       delt = delti*(l1*k); */
                   4277: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4278: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4279: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4280: /*       k1=func(p2)-fx; */
                   4281:       
                   4282: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4283: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4284: /*       k2=func(p2)-fx; */
                   4285:       
                   4286: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4287: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4288: /*       k3=func(p2)-fx; */
                   4289:       
                   4290: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4291: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4292: /*       k4=func(p2)-fx; */
                   4293: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4294: /* #ifdef DEBUGHESSIJ */
                   4295: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4296: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4297: /* #endif */
                   4298: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4299: /*     k=kmax; */
                   4300: /*       } */
                   4301: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4302: /*     k=kmax; l=lmax*10; */
                   4303: /*       } */
                   4304: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4305: /*     delts=delt; */
                   4306: /*       } */
                   4307: /*     } /\* End loop k *\/ */
                   4308: /*   } */
                   4309: /*   delti[theta]=delts; */
                   4310: /*   return res;  */
                   4311: /* } */
                   4312: 
                   4313: 
1.126     brouard  4314: /************** Inverse of matrix **************/
                   4315: void ludcmp(double **a, int n, int *indx, double *d) 
                   4316: { 
                   4317:   int i,imax,j,k; 
                   4318:   double big,dum,sum,temp; 
                   4319:   double *vv; 
                   4320:  
                   4321:   vv=vector(1,n); 
                   4322:   *d=1.0; 
                   4323:   for (i=1;i<=n;i++) { 
                   4324:     big=0.0; 
                   4325:     for (j=1;j<=n;j++) 
                   4326:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4327:     if (big == 0.0){
                   4328:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4329:       for (j=1;j<=n;j++) {
                   4330:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4331:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4332:       }
                   4333:       fflush(ficlog);
                   4334:       fclose(ficlog);
                   4335:       nrerror("Singular matrix in routine ludcmp"); 
                   4336:     }
1.126     brouard  4337:     vv[i]=1.0/big; 
                   4338:   } 
                   4339:   for (j=1;j<=n;j++) { 
                   4340:     for (i=1;i<j;i++) { 
                   4341:       sum=a[i][j]; 
                   4342:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4343:       a[i][j]=sum; 
                   4344:     } 
                   4345:     big=0.0; 
                   4346:     for (i=j;i<=n;i++) { 
                   4347:       sum=a[i][j]; 
                   4348:       for (k=1;k<j;k++) 
                   4349:        sum -= a[i][k]*a[k][j]; 
                   4350:       a[i][j]=sum; 
                   4351:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4352:        big=dum; 
                   4353:        imax=i; 
                   4354:       } 
                   4355:     } 
                   4356:     if (j != imax) { 
                   4357:       for (k=1;k<=n;k++) { 
                   4358:        dum=a[imax][k]; 
                   4359:        a[imax][k]=a[j][k]; 
                   4360:        a[j][k]=dum; 
                   4361:       } 
                   4362:       *d = -(*d); 
                   4363:       vv[imax]=vv[j]; 
                   4364:     } 
                   4365:     indx[j]=imax; 
                   4366:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4367:     if (j != n) { 
                   4368:       dum=1.0/(a[j][j]); 
                   4369:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4370:     } 
                   4371:   } 
                   4372:   free_vector(vv,1,n);  /* Doesn't work */
                   4373: ;
                   4374: } 
                   4375: 
                   4376: void lubksb(double **a, int n, int *indx, double b[]) 
                   4377: { 
                   4378:   int i,ii=0,ip,j; 
                   4379:   double sum; 
                   4380:  
                   4381:   for (i=1;i<=n;i++) { 
                   4382:     ip=indx[i]; 
                   4383:     sum=b[ip]; 
                   4384:     b[ip]=b[i]; 
                   4385:     if (ii) 
                   4386:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4387:     else if (sum) ii=i; 
                   4388:     b[i]=sum; 
                   4389:   } 
                   4390:   for (i=n;i>=1;i--) { 
                   4391:     sum=b[i]; 
                   4392:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4393:     b[i]=sum/a[i][i]; 
                   4394:   } 
                   4395: } 
                   4396: 
                   4397: void pstamp(FILE *fichier)
                   4398: {
1.196     brouard  4399:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4400: }
                   4401: 
1.253     brouard  4402: 
                   4403: 
1.126     brouard  4404: /************ Frequencies ********************/
1.251     brouard  4405: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4406:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4407:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4408: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4409:   
1.265     brouard  4410:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4411:   int iind=0, iage=0;
                   4412:   int mi; /* Effective wave */
                   4413:   int first;
                   4414:   double ***freq; /* Frequencies */
1.268     brouard  4415:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4416:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4417:   double *meanq, *stdq, *idq;
1.226     brouard  4418:   double **meanqt;
                   4419:   double *pp, **prop, *posprop, *pospropt;
                   4420:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4421:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4422:   double agebegin, ageend;
                   4423:     
                   4424:   pp=vector(1,nlstate);
1.251     brouard  4425:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4426:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4427:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4428:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4429:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4430:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4431:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4432:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4433:   strcpy(fileresp,"P_");
                   4434:   strcat(fileresp,fileresu);
                   4435:   /*strcat(fileresphtm,fileresu);*/
                   4436:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4437:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4438:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4439:     exit(0);
                   4440:   }
1.240     brouard  4441:   
1.226     brouard  4442:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4443:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4444:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4445:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4446:     fflush(ficlog);
                   4447:     exit(70); 
                   4448:   }
                   4449:   else{
                   4450:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4451: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4452: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4453:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4454:   }
1.237     brouard  4455:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4456:   
1.226     brouard  4457:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4458:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4459:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4460:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4461:     fflush(ficlog);
                   4462:     exit(70); 
1.240     brouard  4463:   } else{
1.226     brouard  4464:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4465: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4466: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4467:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4468:   }
1.240     brouard  4469:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4470:   
1.253     brouard  4471:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4472:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4473:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4474:   j1=0;
1.126     brouard  4475:   
1.227     brouard  4476:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4477:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4478:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4479:   
                   4480:   
1.226     brouard  4481:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4482:      reference=low_education V1=0,V2=0
                   4483:      med_educ                V1=1 V2=0, 
                   4484:      high_educ               V1=0 V2=1
                   4485:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4486:   */
1.249     brouard  4487:   dateintsum=0;
                   4488:   k2cpt=0;
                   4489: 
1.253     brouard  4490:   if(cptcoveff == 0 )
1.265     brouard  4491:     nl=1;  /* Constant and age model only */
1.253     brouard  4492:   else
                   4493:     nl=2;
1.265     brouard  4494: 
                   4495:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4496:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4497:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4498:    *     freq[s1][s2][iage] =0.
                   4499:    *     Loop on iind
                   4500:    *       ++freq[s1][s2][iage] weighted
                   4501:    *     end iind
                   4502:    *     if covariate and j!0
                   4503:    *       headers Variable on one line
                   4504:    *     endif cov j!=0
                   4505:    *     header of frequency table by age
                   4506:    *     Loop on age
                   4507:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4508:    *       pos+=freq[s1][s2][iage] weighted
                   4509:    *       Loop on s1 initial state
                   4510:    *         fprintf(ficresp
                   4511:    *       end s1
                   4512:    *     end age
                   4513:    *     if j!=0 computes starting values
                   4514:    *     end compute starting values
                   4515:    *   end j1
                   4516:    * end nl 
                   4517:    */
1.253     brouard  4518:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4519:     if(nj==1)
                   4520:       j=0;  /* First pass for the constant */
1.265     brouard  4521:     else{
1.253     brouard  4522:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4523:     }
1.251     brouard  4524:     first=1;
1.265     brouard  4525:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4526:       posproptt=0.;
                   4527:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4528:        scanf("%d", i);*/
                   4529:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4530:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4531:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4532:            freq[i][s2][m]=0;
1.251     brouard  4533:       
                   4534:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4535:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4536:          prop[i][m]=0;
                   4537:        posprop[i]=0;
                   4538:        pospropt[i]=0;
                   4539:       }
1.283     brouard  4540:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4541:         idq[z1]=0.;
                   4542:         meanq[z1]=0.;
                   4543:         stdq[z1]=0.;
1.283     brouard  4544:       }
                   4545:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4546:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4547:       /*         meanqt[m][z1]=0.; */
                   4548:       /*       } */
                   4549:       /* }       */
1.251     brouard  4550:       /* dateintsum=0; */
                   4551:       /* k2cpt=0; */
                   4552:       
1.265     brouard  4553:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4554:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4555:        bool=1;
                   4556:        if(j !=0){
                   4557:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4558:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4559:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4560:                /* if(Tvaraff[z1] ==-20){ */
                   4561:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4562:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4563:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4564:                /* }else  */
                   4565:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4566:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4567:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4568:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4569:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4570:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4571:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4572:                } /* Onlyf fixed */
                   4573:              } /* end z1 */
                   4574:            } /* cptcovn > 0 */
                   4575:          } /* end any */
                   4576:        }/* end j==0 */
1.265     brouard  4577:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4578:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4579:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4580:            m=mw[mi][iind];
                   4581:            if(j!=0){
                   4582:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4583:                for (z1=1; z1<=cptcoveff; z1++) {
                   4584:                  if( Fixed[Tmodelind[z1]]==1){
                   4585:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4586:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4587:                                                                                      value is -1, we don't select. It differs from the 
                   4588:                                                                                      constant and age model which counts them. */
                   4589:                      bool=0; /* not selected */
                   4590:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4591:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4592:                      bool=0;
                   4593:                    }
                   4594:                  }
                   4595:                }
                   4596:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4597:            } /* end j==0 */
                   4598:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4599:            if(bool==1){ /*Selected */
1.251     brouard  4600:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4601:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4602:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4603:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4604:              if(m >=firstpass && m <=lastpass){
                   4605:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4606:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4607:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4608:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4609:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4610:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4611:                if (m<lastpass) {
                   4612:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4613:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4614:                  if(s[m][iind]==-1)
                   4615:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4616:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.284     brouard  4617:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean */
                   4618:                    idq[z1]=idq[z1]+weight[iind];
                   4619:                    meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4620:                    stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4621:                  }
1.251     brouard  4622:                  /* if((int)agev[m][iind] == 55) */
                   4623:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4624:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4625:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4626:                }
1.251     brouard  4627:              } /* end if between passes */  
                   4628:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4629:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4630:                k2cpt++;
                   4631:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4632:              }
1.251     brouard  4633:            }else{
                   4634:              bool=1;
                   4635:            }/* end bool 2 */
                   4636:          } /* end m */
1.284     brouard  4637:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4638:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4639:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4640:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4641:          /* } */
1.251     brouard  4642:        } /* end bool */
                   4643:       } /* end iind = 1 to imx */
                   4644:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4645:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4646:       
                   4647:       
                   4648:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4649:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4650:         pstamp(ficresp);
1.251     brouard  4651:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4652:         pstamp(ficresp);
1.251     brouard  4653:        printf( "\n#********** Variable "); 
                   4654:        fprintf(ficresp, "\n#********** Variable "); 
                   4655:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4656:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4657:        fprintf(ficlog, "\n#********** Variable "); 
                   4658:        for (z1=1; z1<=cptcoveff; z1++){
                   4659:          if(!FixedV[Tvaraff[z1]]){
                   4660:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4661:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4662:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4663:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4664:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4665:          }else{
1.251     brouard  4666:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4667:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4668:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4669:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4670:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4671:          }
                   4672:        }
                   4673:        printf( "**********\n#");
                   4674:        fprintf(ficresp, "**********\n#");
                   4675:        fprintf(ficresphtm, "**********</h3>\n");
                   4676:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4677:        fprintf(ficlog, "**********\n");
                   4678:       }
1.284     brouard  4679:       /*
                   4680:        Printing means of quantitative variables if any
                   4681:       */
                   4682:       for (z1=1; z1<= nqfveff; z1++) {
1.285     brouard  4683:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.0f individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.284     brouard  4684:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
                   4685:        if(weightopt==1){
                   4686:          printf(" Weighted mean and standard deviation of");
                   4687:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4688:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4689:        }
1.285     brouard  4690:        printf(" fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4691:        fprintf(ficlog," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4692:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
1.284     brouard  4693:       }
                   4694:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4695:       /*       for(m=1;m<=lastpass;m++){ */
                   4696:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4697:       /*   } */
                   4698:       /* } */
1.283     brouard  4699: 
1.251     brouard  4700:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4701:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4702:         fprintf(ficresp, " Age");
                   4703:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4704:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4705:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4706:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4707:       }
1.265     brouard  4708:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4709:       fprintf(ficresphtm, "\n");
                   4710:       
                   4711:       /* Header of frequency table by age */
                   4712:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4713:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4714:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4715:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4716:          if(s2!=0 && m!=0)
                   4717:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4718:        }
1.226     brouard  4719:       }
1.251     brouard  4720:       fprintf(ficresphtmfr, "\n");
                   4721:     
                   4722:       /* For each age */
                   4723:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4724:        fprintf(ficresphtm,"<tr>");
                   4725:        if(iage==iagemax+1){
                   4726:          fprintf(ficlog,"1");
                   4727:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4728:        }else if(iage==iagemax+2){
                   4729:          fprintf(ficlog,"0");
                   4730:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4731:        }else if(iage==iagemax+3){
                   4732:          fprintf(ficlog,"Total");
                   4733:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4734:        }else{
1.240     brouard  4735:          if(first==1){
1.251     brouard  4736:            first=0;
                   4737:            printf("See log file for details...\n");
                   4738:          }
                   4739:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4740:          fprintf(ficlog,"Age %d", iage);
                   4741:        }
1.265     brouard  4742:        for(s1=1; s1 <=nlstate ; s1++){
                   4743:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4744:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4745:        }
1.265     brouard  4746:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4747:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4748:            pos += freq[s1][m][iage];
                   4749:          if(pp[s1]>=1.e-10){
1.251     brouard  4750:            if(first==1){
1.265     brouard  4751:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4752:            }
1.265     brouard  4753:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4754:          }else{
                   4755:            if(first==1)
1.265     brouard  4756:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4757:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4758:          }
                   4759:        }
                   4760:       
1.265     brouard  4761:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4762:          /* posprop[s1]=0; */
                   4763:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4764:            pp[s1] += freq[s1][m][iage];
                   4765:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4766:       
                   4767:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4768:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4769:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4770:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4771:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4772:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4773:        }
                   4774:        
                   4775:        /* Writing ficresp */
                   4776:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4777:           if( iage <= iagemax){
                   4778:            fprintf(ficresp," %d",iage);
                   4779:           }
                   4780:         }else if( nj==2){
                   4781:           if( iage <= iagemax){
                   4782:            fprintf(ficresp," %d",iage);
                   4783:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4784:           }
1.240     brouard  4785:        }
1.265     brouard  4786:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4787:          if(pos>=1.e-5){
1.251     brouard  4788:            if(first==1)
1.265     brouard  4789:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4790:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4791:          }else{
                   4792:            if(first==1)
1.265     brouard  4793:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4794:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4795:          }
                   4796:          if( iage <= iagemax){
                   4797:            if(pos>=1.e-5){
1.265     brouard  4798:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4799:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4800:               }else if( nj==2){
                   4801:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4802:               }
                   4803:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4804:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4805:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4806:            } else{
                   4807:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4808:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4809:            }
1.240     brouard  4810:          }
1.265     brouard  4811:          pospropt[s1] +=posprop[s1];
                   4812:        } /* end loop s1 */
1.251     brouard  4813:        /* pospropt=0.; */
1.265     brouard  4814:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4815:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4816:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4817:              if(first==1){
1.265     brouard  4818:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4819:              }
1.265     brouard  4820:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4821:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4822:            }
1.265     brouard  4823:            if(s1!=0 && m!=0)
                   4824:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4825:          }
1.265     brouard  4826:        } /* end loop s1 */
1.251     brouard  4827:        posproptt=0.; 
1.265     brouard  4828:        for(s1=1; s1 <=nlstate; s1++){
                   4829:          posproptt += pospropt[s1];
1.251     brouard  4830:        }
                   4831:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4832:        fprintf(ficresphtm,"</tr>\n");
                   4833:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4834:          if(iage <= iagemax)
                   4835:            fprintf(ficresp,"\n");
1.240     brouard  4836:        }
1.251     brouard  4837:        if(first==1)
                   4838:          printf("Others in log...\n");
                   4839:        fprintf(ficlog,"\n");
                   4840:       } /* end loop age iage */
1.265     brouard  4841:       
1.251     brouard  4842:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4843:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4844:        if(posproptt < 1.e-5){
1.265     brouard  4845:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4846:        }else{
1.265     brouard  4847:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4848:        }
1.226     brouard  4849:       }
1.251     brouard  4850:       fprintf(ficresphtm,"</tr>\n");
                   4851:       fprintf(ficresphtm,"</table>\n");
                   4852:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4853:       if(posproptt < 1.e-5){
1.251     brouard  4854:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4855:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4856:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4857:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4858:        invalidvarcomb[j1]=1;
1.226     brouard  4859:       }else{
1.251     brouard  4860:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4861:        invalidvarcomb[j1]=0;
1.226     brouard  4862:       }
1.251     brouard  4863:       fprintf(ficresphtmfr,"</table>\n");
                   4864:       fprintf(ficlog,"\n");
                   4865:       if(j!=0){
                   4866:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4867:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4868:          for(k=1; k <=(nlstate+ndeath); k++){
                   4869:            if (k != i) {
1.265     brouard  4870:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4871:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4872:                  if(j1==1){ /* All dummy covariates to zero */
                   4873:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4874:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4875:                    printf("%d%d ",i,k);
                   4876:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4877:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4878:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4879:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4880:                  }
1.253     brouard  4881:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4882:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4883:                    x[iage]= (double)iage;
                   4884:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4885:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4886:                  }
1.268     brouard  4887:                  /* Some are not finite, but linreg will ignore these ages */
                   4888:                  no=0;
1.253     brouard  4889:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4890:                  pstart[s1]=b;
                   4891:                  pstart[s1-1]=a;
1.252     brouard  4892:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4893:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4894:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4895:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4896:                  printf("%d%d ",i,k);
                   4897:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4898:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4899:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4900:                  ;
                   4901:                }
                   4902:                /* printf("%12.7f )", param[i][jj][k]); */
                   4903:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4904:                s1++; 
1.251     brouard  4905:              } /* end jj */
                   4906:            } /* end k!= i */
                   4907:          } /* end k */
1.265     brouard  4908:        } /* end i, s1 */
1.251     brouard  4909:       } /* end j !=0 */
                   4910:     } /* end selected combination of covariate j1 */
                   4911:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4912:       printf("#Freqsummary: Starting values for the constants:\n");
                   4913:       fprintf(ficlog,"\n");
1.265     brouard  4914:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4915:        for(k=1; k <=(nlstate+ndeath); k++){
                   4916:          if (k != i) {
                   4917:            printf("%d%d ",i,k);
                   4918:            fprintf(ficlog,"%d%d ",i,k);
                   4919:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4920:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4921:              if(jj==1){ /* Age has to be done */
1.265     brouard  4922:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4923:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4924:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4925:              }
                   4926:              /* printf("%12.7f )", param[i][jj][k]); */
                   4927:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4928:              s1++; 
1.250     brouard  4929:            }
1.251     brouard  4930:            printf("\n");
                   4931:            fprintf(ficlog,"\n");
1.250     brouard  4932:          }
                   4933:        }
1.284     brouard  4934:       } /* end of state i */
1.251     brouard  4935:       printf("#Freqsummary\n");
                   4936:       fprintf(ficlog,"\n");
1.265     brouard  4937:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4938:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4939:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4940:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4941:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4942:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   4943:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   4944:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  4945:          /* } */
                   4946:        }
1.265     brouard  4947:       } /* end loop s1 */
1.251     brouard  4948:       
                   4949:       printf("\n");
                   4950:       fprintf(ficlog,"\n");
                   4951:     } /* end j=0 */
1.249     brouard  4952:   } /* end j */
1.252     brouard  4953: 
1.253     brouard  4954:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  4955:     for(i=1, jk=1; i <=nlstate; i++){
                   4956:       for(j=1; j <=nlstate+ndeath; j++){
                   4957:        if(j!=i){
                   4958:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   4959:          printf("%1d%1d",i,j);
                   4960:          fprintf(ficparo,"%1d%1d",i,j);
                   4961:          for(k=1; k<=ncovmodel;k++){
                   4962:            /*    printf(" %lf",param[i][j][k]); */
                   4963:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   4964:            p[jk]=pstart[jk];
                   4965:            printf(" %f ",pstart[jk]);
                   4966:            fprintf(ficparo," %f ",pstart[jk]);
                   4967:            jk++;
                   4968:          }
                   4969:          printf("\n");
                   4970:          fprintf(ficparo,"\n");
                   4971:        }
                   4972:       }
                   4973:     }
                   4974:   } /* end mle=-2 */
1.226     brouard  4975:   dateintmean=dateintsum/k2cpt; 
1.240     brouard  4976:   
1.226     brouard  4977:   fclose(ficresp);
                   4978:   fclose(ficresphtm);
                   4979:   fclose(ficresphtmfr);
1.283     brouard  4980:   free_vector(idq,1,nqfveff);
1.226     brouard  4981:   free_vector(meanq,1,nqfveff);
1.284     brouard  4982:   free_vector(stdq,1,nqfveff);
1.226     brouard  4983:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  4984:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   4985:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  4986:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4987:   free_vector(pospropt,1,nlstate);
                   4988:   free_vector(posprop,1,nlstate);
1.251     brouard  4989:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  4990:   free_vector(pp,1,nlstate);
                   4991:   /* End of freqsummary */
                   4992: }
1.126     brouard  4993: 
1.268     brouard  4994: /* Simple linear regression */
                   4995: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   4996: 
                   4997:   /* y=a+bx regression */
                   4998:   double   sumx = 0.0;                        /* sum of x                      */
                   4999:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   5000:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   5001:   double   sumy = 0.0;                        /* sum of y                      */
                   5002:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   5003:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   5004:   double yhat;
                   5005:   
                   5006:   double denom=0;
                   5007:   int i;
                   5008:   int ne=*no;
                   5009:   
                   5010:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5011:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5012:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5013:       continue;
                   5014:     }
                   5015:     ne=ne+1;
                   5016:     sumx  += x[i];       
                   5017:     sumx2 += x[i]*x[i];  
                   5018:     sumxy += x[i] * y[i];
                   5019:     sumy  += y[i];      
                   5020:     sumy2 += y[i]*y[i]; 
                   5021:     denom = (ne * sumx2 - sumx*sumx);
                   5022:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5023:   } 
                   5024:   
                   5025:   denom = (ne * sumx2 - sumx*sumx);
                   5026:   if (denom == 0) {
                   5027:     // vertical, slope m is infinity
                   5028:     *b = INFINITY;
                   5029:     *a = 0;
                   5030:     if (r) *r = 0;
                   5031:     return 1;
                   5032:   }
                   5033:   
                   5034:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5035:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5036:   if (r!=NULL) {
                   5037:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5038:       sqrt((sumx2 - sumx*sumx/ne) *
                   5039:           (sumy2 - sumy*sumy/ne));
                   5040:   }
                   5041:   *no=ne;
                   5042:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5043:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5044:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5045:       continue;
                   5046:     }
                   5047:     ne=ne+1;
                   5048:     yhat = y[i] - *a -*b* x[i];
                   5049:     sume2  += yhat * yhat ;       
                   5050:     
                   5051:     denom = (ne * sumx2 - sumx*sumx);
                   5052:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5053:   } 
                   5054:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5055:   *sa= *sb * sqrt(sumx2/ne);
                   5056:   
                   5057:   return 0; 
                   5058: }
                   5059: 
1.126     brouard  5060: /************ Prevalence ********************/
1.227     brouard  5061: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5062: {  
                   5063:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5064:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5065:      We still use firstpass and lastpass as another selection.
                   5066:   */
1.126     brouard  5067:  
1.227     brouard  5068:   int i, m, jk, j1, bool, z1,j, iv;
                   5069:   int mi; /* Effective wave */
                   5070:   int iage;
                   5071:   double agebegin, ageend;
                   5072: 
                   5073:   double **prop;
                   5074:   double posprop; 
                   5075:   double  y2; /* in fractional years */
                   5076:   int iagemin, iagemax;
                   5077:   int first; /** to stop verbosity which is redirected to log file */
                   5078: 
                   5079:   iagemin= (int) agemin;
                   5080:   iagemax= (int) agemax;
                   5081:   /*pp=vector(1,nlstate);*/
1.251     brouard  5082:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5083:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5084:   j1=0;
1.222     brouard  5085:   
1.227     brouard  5086:   /*j=cptcoveff;*/
                   5087:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5088:   
1.288     brouard  5089:   first=0;
1.227     brouard  5090:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5091:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5092:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5093:        prop[i][iage]=0.0;
                   5094:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5095:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5096:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5097:     
                   5098:     for (i=1; i<=imx; i++) { /* Each individual */
                   5099:       bool=1;
                   5100:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5101:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5102:        m=mw[mi][i];
                   5103:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5104:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5105:        for (z1=1; z1<=cptcoveff; z1++){
                   5106:          if( Fixed[Tmodelind[z1]]==1){
                   5107:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5108:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5109:              bool=0;
                   5110:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5111:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5112:              bool=0;
                   5113:            }
                   5114:        }
                   5115:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5116:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5117:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5118:          if(m >=firstpass && m <=lastpass){
                   5119:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5120:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5121:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5122:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5123:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5124:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5125:                exit(1);
                   5126:              }
                   5127:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5128:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5129:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5130:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5131:              } /* end valid statuses */ 
                   5132:            } /* end selection of dates */
                   5133:          } /* end selection of waves */
                   5134:        } /* end bool */
                   5135:       } /* end wave */
                   5136:     } /* end individual */
                   5137:     for(i=iagemin; i <= iagemax+3; i++){  
                   5138:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5139:        posprop += prop[jk][i]; 
                   5140:       } 
                   5141:       
                   5142:       for(jk=1; jk <=nlstate ; jk++){      
                   5143:        if( i <=  iagemax){ 
                   5144:          if(posprop>=1.e-5){ 
                   5145:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5146:          } else{
1.288     brouard  5147:            if(!first){
                   5148:              first=1;
1.266     brouard  5149:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5150:            }else{
1.288     brouard  5151:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5152:            }
                   5153:          }
                   5154:        } 
                   5155:       }/* end jk */ 
                   5156:     }/* end i */ 
1.222     brouard  5157:      /*} *//* end i1 */
1.227     brouard  5158:   } /* end j1 */
1.222     brouard  5159:   
1.227     brouard  5160:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5161:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5162:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5163: }  /* End of prevalence */
1.126     brouard  5164: 
                   5165: /************* Waves Concatenation ***************/
                   5166: 
                   5167: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5168: {
                   5169:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   5170:      Death is a valid wave (if date is known).
                   5171:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5172:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   5173:      and mw[mi+1][i]. dh depends on stepm.
1.227     brouard  5174:   */
1.126     brouard  5175: 
1.224     brouard  5176:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5177:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5178:      double sum=0., jmean=0.;*/
1.224     brouard  5179:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5180:   int j, k=0,jk, ju, jl;
                   5181:   double sum=0.;
                   5182:   first=0;
1.214     brouard  5183:   firstwo=0;
1.217     brouard  5184:   firsthree=0;
1.218     brouard  5185:   firstfour=0;
1.164     brouard  5186:   jmin=100000;
1.126     brouard  5187:   jmax=-1;
                   5188:   jmean=0.;
1.224     brouard  5189: 
                   5190: /* Treating live states */
1.214     brouard  5191:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5192:     mi=0;  /* First valid wave */
1.227     brouard  5193:     mli=0; /* Last valid wave */
1.126     brouard  5194:     m=firstpass;
1.214     brouard  5195:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5196:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5197:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5198:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5199:        mw[++mi][i]=m;
                   5200:        mli=m;
1.224     brouard  5201:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5202:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5203:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5204:       }
1.227     brouard  5205:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5206: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5207:        break;
1.224     brouard  5208: #else
1.227     brouard  5209:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5210:          if(firsthree == 0){
1.262     brouard  5211:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5212:            firsthree=1;
                   5213:          }
1.262     brouard  5214:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p%d%d .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5215:          mw[++mi][i]=m;
                   5216:          mli=m;
                   5217:        }
                   5218:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5219:          nbwarn++;
                   5220:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5221:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5222:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5223:          }
                   5224:          break;
                   5225:        }
                   5226:        break;
1.224     brouard  5227: #endif
1.227     brouard  5228:       }/* End m >= lastpass */
1.126     brouard  5229:     }/* end while */
1.224     brouard  5230: 
1.227     brouard  5231:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5232:     /* After last pass */
1.224     brouard  5233: /* Treating death states */
1.214     brouard  5234:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5235:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5236:       /* } */
1.126     brouard  5237:       mi++;    /* Death is another wave */
                   5238:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5239:       /* Only death is a correct wave */
1.126     brouard  5240:       mw[mi][i]=m;
1.257     brouard  5241:     } /* else not in a death state */
1.224     brouard  5242: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5243:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5244:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5245:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5246:          nbwarn++;
                   5247:          if(firstfiv==0){
                   5248:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5249:            firstfiv=1;
                   5250:          }else{
                   5251:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5252:          }
                   5253:        }else{ /* Death occured afer last wave potential bias */
                   5254:          nberr++;
                   5255:          if(firstwo==0){
1.257     brouard  5256:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5257:            firstwo=1;
                   5258:          }
1.257     brouard  5259:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5260:        }
1.257     brouard  5261:       }else{ /* if date of interview is unknown */
1.227     brouard  5262:        /* death is known but not confirmed by death status at any wave */
                   5263:        if(firstfour==0){
                   5264:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5265:          firstfour=1;
                   5266:        }
                   5267:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5268:       }
1.224     brouard  5269:     } /* end if date of death is known */
                   5270: #endif
                   5271:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5272:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5273:     if(mi==0){
                   5274:       nbwarn++;
                   5275:       if(first==0){
1.227     brouard  5276:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5277:        first=1;
1.126     brouard  5278:       }
                   5279:       if(first==1){
1.227     brouard  5280:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5281:       }
                   5282:     } /* end mi==0 */
                   5283:   } /* End individuals */
1.214     brouard  5284:   /* wav and mw are no more changed */
1.223     brouard  5285:        
1.214     brouard  5286:   
1.126     brouard  5287:   for(i=1; i<=imx; i++){
                   5288:     for(mi=1; mi<wav[i];mi++){
                   5289:       if (stepm <=0)
1.227     brouard  5290:        dh[mi][i]=1;
1.126     brouard  5291:       else{
1.260     brouard  5292:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5293:          if (agedc[i] < 2*AGESUP) {
                   5294:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5295:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5296:            else if(j<0){
                   5297:              nberr++;
                   5298:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5299:              j=1; /* Temporary Dangerous patch */
                   5300:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5301:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5302:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5303:            }
                   5304:            k=k+1;
                   5305:            if (j >= jmax){
                   5306:              jmax=j;
                   5307:              ijmax=i;
                   5308:            }
                   5309:            if (j <= jmin){
                   5310:              jmin=j;
                   5311:              ijmin=i;
                   5312:            }
                   5313:            sum=sum+j;
                   5314:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5315:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5316:          }
                   5317:        }
                   5318:        else{
                   5319:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5320: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5321:                                        
1.227     brouard  5322:          k=k+1;
                   5323:          if (j >= jmax) {
                   5324:            jmax=j;
                   5325:            ijmax=i;
                   5326:          }
                   5327:          else if (j <= jmin){
                   5328:            jmin=j;
                   5329:            ijmin=i;
                   5330:          }
                   5331:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5332:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5333:          if(j<0){
                   5334:            nberr++;
                   5335:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5336:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5337:          }
                   5338:          sum=sum+j;
                   5339:        }
                   5340:        jk= j/stepm;
                   5341:        jl= j -jk*stepm;
                   5342:        ju= j -(jk+1)*stepm;
                   5343:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5344:          if(jl==0){
                   5345:            dh[mi][i]=jk;
                   5346:            bh[mi][i]=0;
                   5347:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5348:                  * to avoid the price of an extra matrix product in likelihood */
                   5349:            dh[mi][i]=jk+1;
                   5350:            bh[mi][i]=ju;
                   5351:          }
                   5352:        }else{
                   5353:          if(jl <= -ju){
                   5354:            dh[mi][i]=jk;
                   5355:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5356:                                 * is higher than the multiple of stepm and negative otherwise.
                   5357:                                 */
                   5358:          }
                   5359:          else{
                   5360:            dh[mi][i]=jk+1;
                   5361:            bh[mi][i]=ju;
                   5362:          }
                   5363:          if(dh[mi][i]==0){
                   5364:            dh[mi][i]=1; /* At least one step */
                   5365:            bh[mi][i]=ju; /* At least one step */
                   5366:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5367:          }
                   5368:        } /* end if mle */
1.126     brouard  5369:       }
                   5370:     } /* end wave */
                   5371:   }
                   5372:   jmean=sum/k;
                   5373:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5374:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5375: }
1.126     brouard  5376: 
                   5377: /*********** Tricode ****************************/
1.220     brouard  5378:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5379:  {
                   5380:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5381:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5382:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5383:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5384:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5385:     */
1.130     brouard  5386: 
1.242     brouard  5387:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5388:    int modmaxcovj=0; /* Modality max of covariates j */
                   5389:    int cptcode=0; /* Modality max of covariates j */
                   5390:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5391: 
                   5392: 
1.242     brouard  5393:    /* cptcoveff=0;  */
                   5394:    /* *cptcov=0; */
1.126     brouard  5395:  
1.242     brouard  5396:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5397:    for (k=1; k <= maxncov; k++)
                   5398:      for(j=1; j<=2; j++)
                   5399:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5400: 
1.242     brouard  5401:    /* Loop on covariates without age and products and no quantitative variable */
                   5402:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5403:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5404:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5405:        switch(Fixed[k]) {
                   5406:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5407:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5408:           ij=(int)(covar[Tvar[k]][i]);
                   5409:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5410:            * If product of Vn*Vm, still boolean *:
                   5411:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5412:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5413:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5414:              modality of the nth covariate of individual i. */
                   5415:           if (ij > modmaxcovj)
                   5416:             modmaxcovj=ij; 
                   5417:           else if (ij < modmincovj) 
                   5418:             modmincovj=ij; 
1.287     brouard  5419:           if (ij <0 || ij >1 ){
                   5420:             printf("Information, IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5421:             fprintf(ficlog,"Information, currently IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5422:           }
                   5423:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5424:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5425:             exit(1);
                   5426:           }else
                   5427:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5428:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5429:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5430:           /* getting the maximum value of the modality of the covariate
                   5431:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5432:              female ies 1, then modmaxcovj=1.
                   5433:           */
                   5434:         } /* end for loop on individuals i */
                   5435:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5436:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5437:         cptcode=modmaxcovj;
                   5438:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5439:         /*for (i=0; i<=cptcode; i++) {*/
                   5440:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5441:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5442:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5443:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5444:             if( j != -1){
                   5445:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5446:                                  covariate for which somebody answered excluding 
                   5447:                                  undefined. Usually 2: 0 and 1. */
                   5448:             }
                   5449:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5450:                                     covariate for which somebody answered including 
                   5451:                                     undefined. Usually 3: -1, 0 and 1. */
                   5452:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5453:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5454:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5455:                        
1.242     brouard  5456:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5457:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5458:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5459:         /* modmincovj=3; modmaxcovj = 7; */
                   5460:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5461:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5462:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5463:         /* nbcode[Tvar[j]][ij]=k; */
                   5464:         /* nbcode[Tvar[j]][1]=0; */
                   5465:         /* nbcode[Tvar[j]][2]=1; */
                   5466:         /* nbcode[Tvar[j]][3]=2; */
                   5467:         /* To be continued (not working yet). */
                   5468:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5469: 
                   5470:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5471:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5472:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5473:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5474:         /*, could be restored in the future */
                   5475:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5476:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5477:             break;
                   5478:           }
                   5479:           ij++;
1.287     brouard  5480:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5481:           cptcode = ij; /* New max modality for covar j */
                   5482:         } /* end of loop on modality i=-1 to 1 or more */
                   5483:         break;
                   5484:        case 1: /* Testing on varying covariate, could be simple and
                   5485:                * should look at waves or product of fixed *
                   5486:                * varying. No time to test -1, assuming 0 and 1 only */
                   5487:         ij=0;
                   5488:         for(i=0; i<=1;i++){
                   5489:           nbcode[Tvar[k]][++ij]=i;
                   5490:         }
                   5491:         break;
                   5492:        default:
                   5493:         break;
                   5494:        } /* end switch */
                   5495:      } /* end dummy test */
1.287     brouard  5496:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5497:   
                   5498:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5499:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5500:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5501:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5502:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5503:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5504:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5505:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5506:   
                   5507:    ij=0;
                   5508:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5509:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5510:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5511:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5512:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5513:        /* If product not in single variable we don't print results */
                   5514:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5515:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5516:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5517:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5518:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5519:        if(Fixed[k]!=0)
                   5520:         anyvaryingduminmodel=1;
                   5521:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5522:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5523:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5524:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5525:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5526:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5527:      } 
                   5528:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5529:    /* ij--; */
                   5530:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5531:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5532:                * because they can be excluded from the model and real
                   5533:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5534:    for(j=ij+1; j<= cptcovt; j++){
                   5535:      Tvaraff[j]=0;
                   5536:      Tmodelind[j]=0;
                   5537:    }
                   5538:    for(j=ntveff+1; j<= cptcovt; j++){
                   5539:      TmodelInvind[j]=0;
                   5540:    }
                   5541:    /* To be sorted */
                   5542:    ;
                   5543:  }
1.126     brouard  5544: 
1.145     brouard  5545: 
1.126     brouard  5546: /*********** Health Expectancies ****************/
                   5547: 
1.235     brouard  5548:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5549: 
                   5550: {
                   5551:   /* Health expectancies, no variances */
1.164     brouard  5552:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5553:   int nhstepma, nstepma; /* Decreasing with age */
                   5554:   double age, agelim, hf;
                   5555:   double ***p3mat;
                   5556:   double eip;
                   5557: 
1.238     brouard  5558:   /* pstamp(ficreseij); */
1.126     brouard  5559:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5560:   fprintf(ficreseij,"# Age");
                   5561:   for(i=1; i<=nlstate;i++){
                   5562:     for(j=1; j<=nlstate;j++){
                   5563:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5564:     }
                   5565:     fprintf(ficreseij," e%1d. ",i);
                   5566:   }
                   5567:   fprintf(ficreseij,"\n");
                   5568: 
                   5569:   
                   5570:   if(estepm < stepm){
                   5571:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5572:   }
                   5573:   else  hstepm=estepm;   
                   5574:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5575:    * This is mainly to measure the difference between two models: for example
                   5576:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5577:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5578:    * progression in between and thus overestimating or underestimating according
                   5579:    * to the curvature of the survival function. If, for the same date, we 
                   5580:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5581:    * to compare the new estimate of Life expectancy with the same linear 
                   5582:    * hypothesis. A more precise result, taking into account a more precise
                   5583:    * curvature will be obtained if estepm is as small as stepm. */
                   5584: 
                   5585:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5586:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5587:      nhstepm is the number of hstepm from age to agelim 
                   5588:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5589:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5590:      and note for a fixed period like estepm months */
                   5591:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5592:      survival function given by stepm (the optimization length). Unfortunately it
                   5593:      means that if the survival funtion is printed only each two years of age and if
                   5594:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5595:      results. So we changed our mind and took the option of the best precision.
                   5596:   */
                   5597:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5598: 
                   5599:   agelim=AGESUP;
                   5600:   /* If stepm=6 months */
                   5601:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5602:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5603:     
                   5604: /* nhstepm age range expressed in number of stepm */
                   5605:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5606:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5607:   /* if (stepm >= YEARM) hstepm=1;*/
                   5608:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5609:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5610: 
                   5611:   for (age=bage; age<=fage; age ++){ 
                   5612:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5613:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5614:     /* if (stepm >= YEARM) hstepm=1;*/
                   5615:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5616: 
                   5617:     /* If stepm=6 months */
                   5618:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5619:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5620:     
1.235     brouard  5621:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5622:     
                   5623:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5624:     
                   5625:     printf("%d|",(int)age);fflush(stdout);
                   5626:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5627:     
                   5628:     /* Computing expectancies */
                   5629:     for(i=1; i<=nlstate;i++)
                   5630:       for(j=1; j<=nlstate;j++)
                   5631:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5632:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5633:          
                   5634:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5635: 
                   5636:        }
                   5637: 
                   5638:     fprintf(ficreseij,"%3.0f",age );
                   5639:     for(i=1; i<=nlstate;i++){
                   5640:       eip=0;
                   5641:       for(j=1; j<=nlstate;j++){
                   5642:        eip +=eij[i][j][(int)age];
                   5643:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5644:       }
                   5645:       fprintf(ficreseij,"%9.4f", eip );
                   5646:     }
                   5647:     fprintf(ficreseij,"\n");
                   5648:     
                   5649:   }
                   5650:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5651:   printf("\n");
                   5652:   fprintf(ficlog,"\n");
                   5653:   
                   5654: }
                   5655: 
1.235     brouard  5656:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5657: 
                   5658: {
                   5659:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5660:      to initial status i, ei. .
1.126     brouard  5661:   */
                   5662:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5663:   int nhstepma, nstepma; /* Decreasing with age */
                   5664:   double age, agelim, hf;
                   5665:   double ***p3matp, ***p3matm, ***varhe;
                   5666:   double **dnewm,**doldm;
                   5667:   double *xp, *xm;
                   5668:   double **gp, **gm;
                   5669:   double ***gradg, ***trgradg;
                   5670:   int theta;
                   5671: 
                   5672:   double eip, vip;
                   5673: 
                   5674:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5675:   xp=vector(1,npar);
                   5676:   xm=vector(1,npar);
                   5677:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5678:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5679:   
                   5680:   pstamp(ficresstdeij);
                   5681:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5682:   fprintf(ficresstdeij,"# Age");
                   5683:   for(i=1; i<=nlstate;i++){
                   5684:     for(j=1; j<=nlstate;j++)
                   5685:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5686:     fprintf(ficresstdeij," e%1d. ",i);
                   5687:   }
                   5688:   fprintf(ficresstdeij,"\n");
                   5689: 
                   5690:   pstamp(ficrescveij);
                   5691:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5692:   fprintf(ficrescveij,"# Age");
                   5693:   for(i=1; i<=nlstate;i++)
                   5694:     for(j=1; j<=nlstate;j++){
                   5695:       cptj= (j-1)*nlstate+i;
                   5696:       for(i2=1; i2<=nlstate;i2++)
                   5697:        for(j2=1; j2<=nlstate;j2++){
                   5698:          cptj2= (j2-1)*nlstate+i2;
                   5699:          if(cptj2 <= cptj)
                   5700:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5701:        }
                   5702:     }
                   5703:   fprintf(ficrescveij,"\n");
                   5704:   
                   5705:   if(estepm < stepm){
                   5706:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5707:   }
                   5708:   else  hstepm=estepm;   
                   5709:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5710:    * This is mainly to measure the difference between two models: for example
                   5711:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5712:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5713:    * progression in between and thus overestimating or underestimating according
                   5714:    * to the curvature of the survival function. If, for the same date, we 
                   5715:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5716:    * to compare the new estimate of Life expectancy with the same linear 
                   5717:    * hypothesis. A more precise result, taking into account a more precise
                   5718:    * curvature will be obtained if estepm is as small as stepm. */
                   5719: 
                   5720:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5721:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5722:      nhstepm is the number of hstepm from age to agelim 
                   5723:      nstepm is the number of stepm from age to agelin. 
                   5724:      Look at hpijx to understand the reason of that which relies in memory size
                   5725:      and note for a fixed period like estepm months */
                   5726:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5727:      survival function given by stepm (the optimization length). Unfortunately it
                   5728:      means that if the survival funtion is printed only each two years of age and if
                   5729:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5730:      results. So we changed our mind and took the option of the best precision.
                   5731:   */
                   5732:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5733: 
                   5734:   /* If stepm=6 months */
                   5735:   /* nhstepm age range expressed in number of stepm */
                   5736:   agelim=AGESUP;
                   5737:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5738:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5739:   /* if (stepm >= YEARM) hstepm=1;*/
                   5740:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5741:   
                   5742:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5743:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5744:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5745:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5746:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5747:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5748: 
                   5749:   for (age=bage; age<=fage; age ++){ 
                   5750:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5751:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5752:     /* if (stepm >= YEARM) hstepm=1;*/
                   5753:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5754:                
1.126     brouard  5755:     /* If stepm=6 months */
                   5756:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5757:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5758:     
                   5759:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5760:                
1.126     brouard  5761:     /* Computing  Variances of health expectancies */
                   5762:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5763:        decrease memory allocation */
                   5764:     for(theta=1; theta <=npar; theta++){
                   5765:       for(i=1; i<=npar; i++){ 
1.222     brouard  5766:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5767:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5768:       }
1.235     brouard  5769:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5770:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5771:                        
1.126     brouard  5772:       for(j=1; j<= nlstate; j++){
1.222     brouard  5773:        for(i=1; i<=nlstate; i++){
                   5774:          for(h=0; h<=nhstepm-1; h++){
                   5775:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5776:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5777:          }
                   5778:        }
1.126     brouard  5779:       }
1.218     brouard  5780:                        
1.126     brouard  5781:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5782:        for(h=0; h<=nhstepm-1; h++){
                   5783:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5784:        }
1.126     brouard  5785:     }/* End theta */
                   5786:     
                   5787:     
                   5788:     for(h=0; h<=nhstepm-1; h++)
                   5789:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5790:        for(theta=1; theta <=npar; theta++)
                   5791:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5792:     
1.218     brouard  5793:                
1.222     brouard  5794:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5795:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5796:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5797:                
1.222     brouard  5798:     printf("%d|",(int)age);fflush(stdout);
                   5799:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5800:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5801:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5802:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5803:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5804:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5805:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5806:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5807:       }
                   5808:     }
1.218     brouard  5809:                
1.126     brouard  5810:     /* Computing expectancies */
1.235     brouard  5811:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5812:     for(i=1; i<=nlstate;i++)
                   5813:       for(j=1; j<=nlstate;j++)
1.222     brouard  5814:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5815:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5816:                                        
1.222     brouard  5817:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5818:                                        
1.222     brouard  5819:        }
1.269     brouard  5820: 
                   5821:     /* Standard deviation of expectancies ij */                
1.126     brouard  5822:     fprintf(ficresstdeij,"%3.0f",age );
                   5823:     for(i=1; i<=nlstate;i++){
                   5824:       eip=0.;
                   5825:       vip=0.;
                   5826:       for(j=1; j<=nlstate;j++){
1.222     brouard  5827:        eip += eij[i][j][(int)age];
                   5828:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5829:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5830:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5831:       }
                   5832:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5833:     }
                   5834:     fprintf(ficresstdeij,"\n");
1.218     brouard  5835:                
1.269     brouard  5836:     /* Variance of expectancies ij */          
1.126     brouard  5837:     fprintf(ficrescveij,"%3.0f",age );
                   5838:     for(i=1; i<=nlstate;i++)
                   5839:       for(j=1; j<=nlstate;j++){
1.222     brouard  5840:        cptj= (j-1)*nlstate+i;
                   5841:        for(i2=1; i2<=nlstate;i2++)
                   5842:          for(j2=1; j2<=nlstate;j2++){
                   5843:            cptj2= (j2-1)*nlstate+i2;
                   5844:            if(cptj2 <= cptj)
                   5845:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5846:          }
1.126     brouard  5847:       }
                   5848:     fprintf(ficrescveij,"\n");
1.218     brouard  5849:                
1.126     brouard  5850:   }
                   5851:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5852:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5853:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5854:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5855:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5856:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5857:   printf("\n");
                   5858:   fprintf(ficlog,"\n");
1.218     brouard  5859:        
1.126     brouard  5860:   free_vector(xm,1,npar);
                   5861:   free_vector(xp,1,npar);
                   5862:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5863:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5864:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5865: }
1.218     brouard  5866:  
1.126     brouard  5867: /************ Variance ******************/
1.235     brouard  5868:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5869:  {
1.279     brouard  5870:    /** Variance of health expectancies 
                   5871:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5872:     * double **newm;
                   5873:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5874:     */
1.218     brouard  5875:   
                   5876:    /* int movingaverage(); */
                   5877:    double **dnewm,**doldm;
                   5878:    double **dnewmp,**doldmp;
                   5879:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  5880:    int first=0;
1.218     brouard  5881:    int k;
                   5882:    double *xp;
1.279     brouard  5883:    double **gp, **gm;  /**< for var eij */
                   5884:    double ***gradg, ***trgradg; /**< for var eij */
                   5885:    double **gradgp, **trgradgp; /**< for var p point j */
                   5886:    double *gpp, *gmp; /**< for var p point j */
                   5887:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5888:    double ***p3mat;
                   5889:    double age,agelim, hf;
                   5890:    /* double ***mobaverage; */
                   5891:    int theta;
                   5892:    char digit[4];
                   5893:    char digitp[25];
                   5894: 
                   5895:    char fileresprobmorprev[FILENAMELENGTH];
                   5896: 
                   5897:    if(popbased==1){
                   5898:      if(mobilav!=0)
                   5899:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5900:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5901:    }
                   5902:    else 
                   5903:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5904: 
1.218     brouard  5905:    /* if (mobilav!=0) { */
                   5906:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5907:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5908:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5909:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5910:    /*   } */
                   5911:    /* } */
                   5912: 
                   5913:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5914:    sprintf(digit,"%-d",ij);
                   5915:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5916:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5917:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5918:    strcat(fileresprobmorprev,fileresu);
                   5919:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5920:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5921:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5922:    }
                   5923:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5924:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5925:    pstamp(ficresprobmorprev);
                   5926:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5927:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5928:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5929:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5930:    }
                   5931:    for(j=1;j<=cptcoveff;j++) 
                   5932:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5933:    fprintf(ficresprobmorprev,"\n");
                   5934: 
1.218     brouard  5935:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5936:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5937:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5938:      for(i=1; i<=nlstate;i++)
                   5939:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5940:    }  
                   5941:    fprintf(ficresprobmorprev,"\n");
                   5942:   
                   5943:    fprintf(ficgp,"\n# Routine varevsij");
                   5944:    fprintf(ficgp,"\nunset title \n");
                   5945:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   5946:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   5947:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  5948: 
1.218     brouard  5949:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5950:    pstamp(ficresvij);
                   5951:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   5952:    if(popbased==1)
                   5953:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   5954:    else
                   5955:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   5956:    fprintf(ficresvij,"# Age");
                   5957:    for(i=1; i<=nlstate;i++)
                   5958:      for(j=1; j<=nlstate;j++)
                   5959:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   5960:    fprintf(ficresvij,"\n");
                   5961: 
                   5962:    xp=vector(1,npar);
                   5963:    dnewm=matrix(1,nlstate,1,npar);
                   5964:    doldm=matrix(1,nlstate,1,nlstate);
                   5965:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   5966:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   5967: 
                   5968:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   5969:    gpp=vector(nlstate+1,nlstate+ndeath);
                   5970:    gmp=vector(nlstate+1,nlstate+ndeath);
                   5971:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  5972:   
1.218     brouard  5973:    if(estepm < stepm){
                   5974:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   5975:    }
                   5976:    else  hstepm=estepm;   
                   5977:    /* For example we decided to compute the life expectancy with the smallest unit */
                   5978:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5979:       nhstepm is the number of hstepm from age to agelim 
                   5980:       nstepm is the number of stepm from age to agelim. 
                   5981:       Look at function hpijx to understand why because of memory size limitations, 
                   5982:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   5983:       survival function given by stepm (the optimization length). Unfortunately it
                   5984:       means that if the survival funtion is printed every two years of age and if
                   5985:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5986:       results. So we changed our mind and took the option of the best precision.
                   5987:    */
                   5988:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5989:    agelim = AGESUP;
                   5990:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   5991:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   5992:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5993:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5994:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   5995:      gp=matrix(0,nhstepm,1,nlstate);
                   5996:      gm=matrix(0,nhstepm,1,nlstate);
                   5997:                
                   5998:                
                   5999:      for(theta=1; theta <=npar; theta++){
                   6000:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   6001:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6002:        }
1.279     brouard  6003:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   6004:        * returns into prlim .
1.288     brouard  6005:        */
1.242     brouard  6006:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  6007: 
                   6008:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6009:        if (popbased==1) {
                   6010:         if(mobilav ==0){
                   6011:           for(i=1; i<=nlstate;i++)
                   6012:             prlim[i][i]=probs[(int)age][i][ij];
                   6013:         }else{ /* mobilav */ 
                   6014:           for(i=1; i<=nlstate;i++)
                   6015:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6016:         }
                   6017:        }
1.295   ! brouard  6018:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}x\f$ at horizon h.
1.279     brouard  6019:        */                      
                   6020:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292     brouard  6021:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6022:        * at horizon h in state j including mortality.
                   6023:        */
1.218     brouard  6024:        for(j=1; j<= nlstate; j++){
                   6025:         for(h=0; h<=nhstepm; h++){
                   6026:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6027:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6028:         }
                   6029:        }
1.279     brouard  6030:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6031:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6032:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6033:        */
                   6034:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6035:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6036:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6037:        }
                   6038:        
                   6039:        /* Again with minus shift */
1.218     brouard  6040:                        
                   6041:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6042:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6043: 
1.242     brouard  6044:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6045:                        
                   6046:        if (popbased==1) {
                   6047:         if(mobilav ==0){
                   6048:           for(i=1; i<=nlstate;i++)
                   6049:             prlim[i][i]=probs[(int)age][i][ij];
                   6050:         }else{ /* mobilav */ 
                   6051:           for(i=1; i<=nlstate;i++)
                   6052:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6053:         }
                   6054:        }
                   6055:                        
1.235     brouard  6056:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6057:                        
                   6058:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6059:         for(h=0; h<=nhstepm; h++){
                   6060:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6061:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6062:         }
                   6063:        }
                   6064:        /* This for computing probability of death (h=1 means
                   6065:          computed over hstepm matrices product = hstepm*stepm months) 
                   6066:          as a weighted average of prlim.
                   6067:        */
                   6068:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6069:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6070:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6071:        }    
1.279     brouard  6072:        /* end shifting computations */
                   6073: 
                   6074:        /**< Computing gradient matrix at horizon h 
                   6075:        */
1.218     brouard  6076:        for(j=1; j<= nlstate; j++) /* vareij */
                   6077:         for(h=0; h<=nhstepm; h++){
                   6078:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6079:         }
1.279     brouard  6080:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6081:        */
                   6082:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6083:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6084:        }
                   6085:                        
                   6086:      } /* End theta */
1.279     brouard  6087:      
                   6088:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6089:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6090:                
                   6091:      for(h=0; h<=nhstepm; h++) /* veij */
                   6092:        for(j=1; j<=nlstate;j++)
                   6093:         for(theta=1; theta <=npar; theta++)
                   6094:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6095:                
                   6096:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6097:        for(theta=1; theta <=npar; theta++)
                   6098:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6099:      /**< as well as its transposed matrix 
                   6100:       */               
1.218     brouard  6101:                
                   6102:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6103:      for(i=1;i<=nlstate;i++)
                   6104:        for(j=1;j<=nlstate;j++)
                   6105:         vareij[i][j][(int)age] =0.;
1.279     brouard  6106: 
                   6107:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6108:       * and k (nhstepm) formula 15 of article
                   6109:       * Lievre-Brouard-Heathcote
                   6110:       */
                   6111:      
1.218     brouard  6112:      for(h=0;h<=nhstepm;h++){
                   6113:        for(k=0;k<=nhstepm;k++){
                   6114:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6115:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6116:         for(i=1;i<=nlstate;i++)
                   6117:           for(j=1;j<=nlstate;j++)
                   6118:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6119:        }
                   6120:      }
                   6121:                
1.279     brouard  6122:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6123:       * p.j overall mortality formula 49 but computed directly because
                   6124:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6125:       * wix is independent of theta.
                   6126:       */
1.218     brouard  6127:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6128:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6129:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6130:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6131:         varppt[j][i]=doldmp[j][i];
                   6132:      /* end ppptj */
                   6133:      /*  x centered again */
                   6134:                
1.242     brouard  6135:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6136:                
                   6137:      if (popbased==1) {
                   6138:        if(mobilav ==0){
                   6139:         for(i=1; i<=nlstate;i++)
                   6140:           prlim[i][i]=probs[(int)age][i][ij];
                   6141:        }else{ /* mobilav */ 
                   6142:         for(i=1; i<=nlstate;i++)
                   6143:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6144:        }
                   6145:      }
                   6146:                
                   6147:      /* This for computing probability of death (h=1 means
                   6148:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6149:        as a weighted average of prlim.
                   6150:      */
1.235     brouard  6151:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6152:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6153:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6154:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6155:      }    
                   6156:      /* end probability of death */
                   6157:                
                   6158:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6159:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6160:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6161:        for(i=1; i<=nlstate;i++){
                   6162:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6163:        }
                   6164:      } 
                   6165:      fprintf(ficresprobmorprev,"\n");
                   6166:                
                   6167:      fprintf(ficresvij,"%.0f ",age );
                   6168:      for(i=1; i<=nlstate;i++)
                   6169:        for(j=1; j<=nlstate;j++){
                   6170:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6171:        }
                   6172:      fprintf(ficresvij,"\n");
                   6173:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6174:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6175:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6176:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6177:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6178:    } /* End age */
                   6179:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6180:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6181:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6182:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6183:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6184:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6185:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6186:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6187:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6188:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6189:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6190:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6191:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6192:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6193:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6194:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6195:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6196:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6197:     */
1.218     brouard  6198:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6199:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6200: 
1.218     brouard  6201:    free_vector(xp,1,npar);
                   6202:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6203:    free_matrix(dnewm,1,nlstate,1,npar);
                   6204:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6205:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6206:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6207:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6208:    fclose(ficresprobmorprev);
                   6209:    fflush(ficgp);
                   6210:    fflush(fichtm); 
                   6211:  }  /* end varevsij */
1.126     brouard  6212: 
                   6213: /************ Variance of prevlim ******************/
1.269     brouard  6214:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6215: {
1.205     brouard  6216:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6217:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6218: 
1.268     brouard  6219:   double **dnewmpar,**doldm;
1.126     brouard  6220:   int i, j, nhstepm, hstepm;
                   6221:   double *xp;
                   6222:   double *gp, *gm;
                   6223:   double **gradg, **trgradg;
1.208     brouard  6224:   double **mgm, **mgp;
1.126     brouard  6225:   double age,agelim;
                   6226:   int theta;
                   6227:   
                   6228:   pstamp(ficresvpl);
1.288     brouard  6229:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6230:   fprintf(ficresvpl,"# Age ");
                   6231:   if(nresult >=1)
                   6232:     fprintf(ficresvpl," Result# ");
1.126     brouard  6233:   for(i=1; i<=nlstate;i++)
                   6234:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6235:   fprintf(ficresvpl,"\n");
                   6236: 
                   6237:   xp=vector(1,npar);
1.268     brouard  6238:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6239:   doldm=matrix(1,nlstate,1,nlstate);
                   6240:   
                   6241:   hstepm=1*YEARM; /* Every year of age */
                   6242:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6243:   agelim = AGESUP;
                   6244:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6245:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6246:     if (stepm >= YEARM) hstepm=1;
                   6247:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6248:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6249:     mgp=matrix(1,npar,1,nlstate);
                   6250:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6251:     gp=vector(1,nlstate);
                   6252:     gm=vector(1,nlstate);
                   6253: 
                   6254:     for(theta=1; theta <=npar; theta++){
                   6255:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6256:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6257:       }
1.288     brouard  6258:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6259:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6260:       /* else */
                   6261:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6262:       for(i=1;i<=nlstate;i++){
1.126     brouard  6263:        gp[i] = prlim[i][i];
1.208     brouard  6264:        mgp[theta][i] = prlim[i][i];
                   6265:       }
1.126     brouard  6266:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6267:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6268:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6269:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6270:       /* else */
                   6271:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6272:       for(i=1;i<=nlstate;i++){
1.126     brouard  6273:        gm[i] = prlim[i][i];
1.208     brouard  6274:        mgm[theta][i] = prlim[i][i];
                   6275:       }
1.126     brouard  6276:       for(i=1;i<=nlstate;i++)
                   6277:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6278:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6279:     } /* End theta */
                   6280: 
                   6281:     trgradg =matrix(1,nlstate,1,npar);
                   6282: 
                   6283:     for(j=1; j<=nlstate;j++)
                   6284:       for(theta=1; theta <=npar; theta++)
                   6285:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6286:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6287:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6288:     /*   for(j=1; j<=nlstate;j++){ */
                   6289:     /*         printf(" %d ",j); */
                   6290:     /*         for(theta=1; theta <=npar; theta++) */
                   6291:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6292:     /*         printf("\n "); */
                   6293:     /*   } */
                   6294:     /* } */
                   6295:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6296:     /*   printf("\n gradg %d ",(int)age); */
                   6297:     /*   for(j=1; j<=nlstate;j++){ */
                   6298:     /*         printf("%d ",j); */
                   6299:     /*         for(theta=1; theta <=npar; theta++) */
                   6300:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6301:     /*         printf("\n "); */
                   6302:     /*   } */
                   6303:     /* } */
1.126     brouard  6304: 
                   6305:     for(i=1;i<=nlstate;i++)
                   6306:       varpl[i][(int)age] =0.;
1.209     brouard  6307:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6308:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6309:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6310:     }else{
1.268     brouard  6311:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6312:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6313:     }
1.126     brouard  6314:     for(i=1;i<=nlstate;i++)
                   6315:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6316: 
                   6317:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6318:     if(nresult >=1)
                   6319:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6320:     for(i=1; i<=nlstate;i++){
1.126     brouard  6321:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6322:       /* for(j=1;j<=nlstate;j++) */
                   6323:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6324:     }
1.126     brouard  6325:     fprintf(ficresvpl,"\n");
                   6326:     free_vector(gp,1,nlstate);
                   6327:     free_vector(gm,1,nlstate);
1.208     brouard  6328:     free_matrix(mgm,1,npar,1,nlstate);
                   6329:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6330:     free_matrix(gradg,1,npar,1,nlstate);
                   6331:     free_matrix(trgradg,1,nlstate,1,npar);
                   6332:   } /* End age */
                   6333: 
                   6334:   free_vector(xp,1,npar);
                   6335:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6336:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6337: 
                   6338: }
                   6339: 
                   6340: 
                   6341: /************ Variance of backprevalence limit ******************/
1.269     brouard  6342:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6343: {
                   6344:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6345:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6346: 
                   6347:   double **dnewmpar,**doldm;
                   6348:   int i, j, nhstepm, hstepm;
                   6349:   double *xp;
                   6350:   double *gp, *gm;
                   6351:   double **gradg, **trgradg;
                   6352:   double **mgm, **mgp;
                   6353:   double age,agelim;
                   6354:   int theta;
                   6355:   
                   6356:   pstamp(ficresvbl);
                   6357:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6358:   fprintf(ficresvbl,"# Age ");
                   6359:   if(nresult >=1)
                   6360:     fprintf(ficresvbl," Result# ");
                   6361:   for(i=1; i<=nlstate;i++)
                   6362:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6363:   fprintf(ficresvbl,"\n");
                   6364: 
                   6365:   xp=vector(1,npar);
                   6366:   dnewmpar=matrix(1,nlstate,1,npar);
                   6367:   doldm=matrix(1,nlstate,1,nlstate);
                   6368:   
                   6369:   hstepm=1*YEARM; /* Every year of age */
                   6370:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6371:   agelim = AGEINF;
                   6372:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6373:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6374:     if (stepm >= YEARM) hstepm=1;
                   6375:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6376:     gradg=matrix(1,npar,1,nlstate);
                   6377:     mgp=matrix(1,npar,1,nlstate);
                   6378:     mgm=matrix(1,npar,1,nlstate);
                   6379:     gp=vector(1,nlstate);
                   6380:     gm=vector(1,nlstate);
                   6381: 
                   6382:     for(theta=1; theta <=npar; theta++){
                   6383:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6384:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6385:       }
                   6386:       if(mobilavproj > 0 )
                   6387:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6388:       else
                   6389:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6390:       for(i=1;i<=nlstate;i++){
                   6391:        gp[i] = bprlim[i][i];
                   6392:        mgp[theta][i] = bprlim[i][i];
                   6393:       }
                   6394:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6395:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6396:        if(mobilavproj > 0 )
                   6397:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6398:        else
                   6399:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6400:       for(i=1;i<=nlstate;i++){
                   6401:        gm[i] = bprlim[i][i];
                   6402:        mgm[theta][i] = bprlim[i][i];
                   6403:       }
                   6404:       for(i=1;i<=nlstate;i++)
                   6405:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6406:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6407:     } /* End theta */
                   6408: 
                   6409:     trgradg =matrix(1,nlstate,1,npar);
                   6410: 
                   6411:     for(j=1; j<=nlstate;j++)
                   6412:       for(theta=1; theta <=npar; theta++)
                   6413:        trgradg[j][theta]=gradg[theta][j];
                   6414:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6415:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6416:     /*   for(j=1; j<=nlstate;j++){ */
                   6417:     /*         printf(" %d ",j); */
                   6418:     /*         for(theta=1; theta <=npar; theta++) */
                   6419:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6420:     /*         printf("\n "); */
                   6421:     /*   } */
                   6422:     /* } */
                   6423:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6424:     /*   printf("\n gradg %d ",(int)age); */
                   6425:     /*   for(j=1; j<=nlstate;j++){ */
                   6426:     /*         printf("%d ",j); */
                   6427:     /*         for(theta=1; theta <=npar; theta++) */
                   6428:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6429:     /*         printf("\n "); */
                   6430:     /*   } */
                   6431:     /* } */
                   6432: 
                   6433:     for(i=1;i<=nlstate;i++)
                   6434:       varbpl[i][(int)age] =0.;
                   6435:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6436:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6437:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6438:     }else{
                   6439:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6440:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6441:     }
                   6442:     for(i=1;i<=nlstate;i++)
                   6443:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6444: 
                   6445:     fprintf(ficresvbl,"%.0f ",age );
                   6446:     if(nresult >=1)
                   6447:       fprintf(ficresvbl,"%d ",nres );
                   6448:     for(i=1; i<=nlstate;i++)
                   6449:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6450:     fprintf(ficresvbl,"\n");
                   6451:     free_vector(gp,1,nlstate);
                   6452:     free_vector(gm,1,nlstate);
                   6453:     free_matrix(mgm,1,npar,1,nlstate);
                   6454:     free_matrix(mgp,1,npar,1,nlstate);
                   6455:     free_matrix(gradg,1,npar,1,nlstate);
                   6456:     free_matrix(trgradg,1,nlstate,1,npar);
                   6457:   } /* End age */
                   6458: 
                   6459:   free_vector(xp,1,npar);
                   6460:   free_matrix(doldm,1,nlstate,1,npar);
                   6461:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6462: 
                   6463: }
                   6464: 
                   6465: /************ Variance of one-step probabilities  ******************/
                   6466: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6467:  {
                   6468:    int i, j=0,  k1, l1, tj;
                   6469:    int k2, l2, j1,  z1;
                   6470:    int k=0, l;
                   6471:    int first=1, first1, first2;
                   6472:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6473:    double **dnewm,**doldm;
                   6474:    double *xp;
                   6475:    double *gp, *gm;
                   6476:    double **gradg, **trgradg;
                   6477:    double **mu;
                   6478:    double age, cov[NCOVMAX+1];
                   6479:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6480:    int theta;
                   6481:    char fileresprob[FILENAMELENGTH];
                   6482:    char fileresprobcov[FILENAMELENGTH];
                   6483:    char fileresprobcor[FILENAMELENGTH];
                   6484:    double ***varpij;
                   6485: 
                   6486:    strcpy(fileresprob,"PROB_"); 
                   6487:    strcat(fileresprob,fileres);
                   6488:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6489:      printf("Problem with resultfile: %s\n", fileresprob);
                   6490:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6491:    }
                   6492:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6493:    strcat(fileresprobcov,fileresu);
                   6494:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6495:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6496:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6497:    }
                   6498:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6499:    strcat(fileresprobcor,fileresu);
                   6500:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6501:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6502:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6503:    }
                   6504:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6505:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6506:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6507:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6508:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6509:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6510:    pstamp(ficresprob);
                   6511:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6512:    fprintf(ficresprob,"# Age");
                   6513:    pstamp(ficresprobcov);
                   6514:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6515:    fprintf(ficresprobcov,"# Age");
                   6516:    pstamp(ficresprobcor);
                   6517:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6518:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6519: 
                   6520: 
1.222     brouard  6521:    for(i=1; i<=nlstate;i++)
                   6522:      for(j=1; j<=(nlstate+ndeath);j++){
                   6523:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6524:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6525:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6526:      }  
                   6527:    /* fprintf(ficresprob,"\n");
                   6528:       fprintf(ficresprobcov,"\n");
                   6529:       fprintf(ficresprobcor,"\n");
                   6530:    */
                   6531:    xp=vector(1,npar);
                   6532:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6533:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6534:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6535:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6536:    first=1;
                   6537:    fprintf(ficgp,"\n# Routine varprob");
                   6538:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6539:    fprintf(fichtm,"\n");
                   6540: 
1.288     brouard  6541:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6542:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6543:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6544: and drawn. It helps understanding how is the covariance between two incidences.\
                   6545:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6546:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6547: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6548: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6549: standard deviations wide on each axis. <br>\
                   6550:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6551:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6552: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6553: 
1.222     brouard  6554:    cov[1]=1;
                   6555:    /* tj=cptcoveff; */
1.225     brouard  6556:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6557:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6558:    j1=0;
1.224     brouard  6559:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6560:      if  (cptcovn>0) {
                   6561:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6562:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6563:        fprintf(ficresprob, "**********\n#\n");
                   6564:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6565:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6566:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6567:                        
1.222     brouard  6568:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6569:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6570:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6571:                        
                   6572:                        
1.222     brouard  6573:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6574:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6575:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6576:                        
1.222     brouard  6577:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6578:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6579:        fprintf(ficresprobcor, "**********\n#");    
                   6580:        if(invalidvarcomb[j1]){
                   6581:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6582:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6583:         continue;
                   6584:        }
                   6585:      }
                   6586:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6587:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6588:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6589:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6590:      for (age=bage; age<=fage; age ++){ 
                   6591:        cov[2]=age;
                   6592:        if(nagesqr==1)
                   6593:         cov[3]= age*age;
                   6594:        for (k=1; k<=cptcovn;k++) {
                   6595:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6596:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6597:                                                                    * 1  1 1 1 1
                   6598:                                                                    * 2  2 1 1 1
                   6599:                                                                    * 3  1 2 1 1
                   6600:                                                                    */
                   6601:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6602:        }
                   6603:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6604:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6605:        for (k=1; k<=cptcovprod;k++)
                   6606:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6607:                        
                   6608:                        
1.222     brouard  6609:        for(theta=1; theta <=npar; theta++){
                   6610:         for(i=1; i<=npar; i++)
                   6611:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6612:                                
1.222     brouard  6613:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6614:                                
1.222     brouard  6615:         k=0;
                   6616:         for(i=1; i<= (nlstate); i++){
                   6617:           for(j=1; j<=(nlstate+ndeath);j++){
                   6618:             k=k+1;
                   6619:             gp[k]=pmmij[i][j];
                   6620:           }
                   6621:         }
1.220     brouard  6622:                                
1.222     brouard  6623:         for(i=1; i<=npar; i++)
                   6624:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6625:                                
1.222     brouard  6626:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6627:         k=0;
                   6628:         for(i=1; i<=(nlstate); i++){
                   6629:           for(j=1; j<=(nlstate+ndeath);j++){
                   6630:             k=k+1;
                   6631:             gm[k]=pmmij[i][j];
                   6632:           }
                   6633:         }
1.220     brouard  6634:                                
1.222     brouard  6635:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6636:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6637:        }
1.126     brouard  6638: 
1.222     brouard  6639:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6640:         for(theta=1; theta <=npar; theta++)
                   6641:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6642:                        
1.222     brouard  6643:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6644:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6645:                        
1.222     brouard  6646:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6647:                        
1.222     brouard  6648:        k=0;
                   6649:        for(i=1; i<=(nlstate); i++){
                   6650:         for(j=1; j<=(nlstate+ndeath);j++){
                   6651:           k=k+1;
                   6652:           mu[k][(int) age]=pmmij[i][j];
                   6653:         }
                   6654:        }
                   6655:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6656:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6657:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6658:                        
1.222     brouard  6659:        /*printf("\n%d ",(int)age);
                   6660:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6661:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6662:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6663:         }*/
1.220     brouard  6664:                        
1.222     brouard  6665:        fprintf(ficresprob,"\n%d ",(int)age);
                   6666:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6667:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6668:                        
1.222     brouard  6669:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6670:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6671:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6672:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6673:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6674:        }
                   6675:        i=0;
                   6676:        for (k=1; k<=(nlstate);k++){
                   6677:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6678:           i++;
                   6679:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6680:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6681:           for (j=1; j<=i;j++){
                   6682:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6683:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6684:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6685:           }
                   6686:         }
                   6687:        }/* end of loop for state */
                   6688:      } /* end of loop for age */
                   6689:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6690:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6691:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6692:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6693:     
                   6694:      /* Confidence intervalle of pij  */
                   6695:      /*
                   6696:        fprintf(ficgp,"\nunset parametric;unset label");
                   6697:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6698:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6699:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6700:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6701:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6702:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6703:      */
                   6704:                
                   6705:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6706:      first1=1;first2=2;
                   6707:      for (k2=1; k2<=(nlstate);k2++){
                   6708:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6709:         if(l2==k2) continue;
                   6710:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6711:         for (k1=1; k1<=(nlstate);k1++){
                   6712:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6713:             if(l1==k1) continue;
                   6714:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6715:             if(i<=j) continue;
                   6716:             for (age=bage; age<=fage; age ++){ 
                   6717:               if ((int)age %5==0){
                   6718:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6719:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6720:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6721:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6722:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6723:                 c12=cv12/sqrt(v1*v2);
                   6724:                 /* Computing eigen value of matrix of covariance */
                   6725:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6726:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6727:                 if ((lc2 <0) || (lc1 <0) ){
                   6728:                   if(first2==1){
                   6729:                     first1=0;
                   6730:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6731:                   }
                   6732:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6733:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6734:                   /* lc2=fabs(lc2); */
                   6735:                 }
1.220     brouard  6736:                                                                
1.222     brouard  6737:                 /* Eigen vectors */
1.280     brouard  6738:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6739:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6740:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6741:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6742:                 }else
                   6743:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6744:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6745:                 v21=(lc1-v1)/cv12*v11;
                   6746:                 v12=-v21;
                   6747:                 v22=v11;
                   6748:                 tnalp=v21/v11;
                   6749:                 if(first1==1){
                   6750:                   first1=0;
                   6751:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6752:                 }
                   6753:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6754:                 /*printf(fignu*/
                   6755:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6756:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6757:                 if(first==1){
                   6758:                   first=0;
                   6759:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6760:                   fprintf(ficgp,"\nset parametric;unset label");
                   6761:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6762:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6763:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6764:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6765: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6766:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6767:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6768:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6769:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6770:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6771:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6772:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6773:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6774:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6775:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6776:                 }else{
                   6777:                   first=0;
                   6778:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6779:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6780:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6781:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6782:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6783:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6784:                 }/* if first */
                   6785:               } /* age mod 5 */
                   6786:             } /* end loop age */
                   6787:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6788:             first=1;
                   6789:           } /*l12 */
                   6790:         } /* k12 */
                   6791:        } /*l1 */
                   6792:      }/* k1 */
                   6793:    }  /* loop on combination of covariates j1 */
                   6794:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6795:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6796:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6797:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6798:    free_vector(xp,1,npar);
                   6799:    fclose(ficresprob);
                   6800:    fclose(ficresprobcov);
                   6801:    fclose(ficresprobcor);
                   6802:    fflush(ficgp);
                   6803:    fflush(fichtmcov);
                   6804:  }
1.126     brouard  6805: 
                   6806: 
                   6807: /******************* Printing html file ***********/
1.201     brouard  6808: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6809:                  int lastpass, int stepm, int weightopt, char model[],\
                   6810:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.258     brouard  6811:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int backcast, int estepm , \
1.273     brouard  6812:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateproj1, double dateback1, \
                   6813:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateproj2, double dateback2){
1.237     brouard  6814:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6815: 
                   6816:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6817:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6818: </ul>");
1.237     brouard  6819:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6820: </ul>", model);
1.214     brouard  6821:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6822:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6823:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6824:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6825:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6826:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6827:    fprintf(fichtm,"\
                   6828:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6829:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6830:    fprintf(fichtm,"\
1.217     brouard  6831:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6832:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6833:    fprintf(fichtm,"\
1.288     brouard  6834:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6835:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6836:    fprintf(fichtm,"\
1.288     brouard  6837:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  6838:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6839:    fprintf(fichtm,"\
1.211     brouard  6840:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6841:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6842:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6843:    if(prevfcast==1){
                   6844:      fprintf(fichtm,"\
                   6845:  - Prevalence projections by age and states:                           \
1.201     brouard  6846:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6847:    }
1.126     brouard  6848: 
                   6849: 
1.225     brouard  6850:    m=pow(2,cptcoveff);
1.222     brouard  6851:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6852: 
1.264     brouard  6853:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6854: 
                   6855:    jj1=0;
                   6856: 
                   6857:    fprintf(fichtm," \n<ul>");
                   6858:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6859:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6860:      if(m != 1 && TKresult[nres]!= k1)
                   6861:        continue;
                   6862:      jj1++;
                   6863:      if (cptcovn > 0) {
                   6864:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6865:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6866:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6867:        }
                   6868:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6869:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6870:        }
                   6871:        fprintf(fichtm,"\">");
                   6872:        
                   6873:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6874:        fprintf(fichtm,"************ Results for covariates");
                   6875:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6876:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6877:        }
                   6878:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6879:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6880:        }
                   6881:        if(invalidvarcomb[k1]){
                   6882:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6883:         continue;
                   6884:        }
                   6885:        fprintf(fichtm,"</a></li>");
                   6886:      } /* cptcovn >0 */
                   6887:    }
                   6888:      fprintf(fichtm," \n</ul>");
                   6889: 
1.222     brouard  6890:    jj1=0;
1.237     brouard  6891: 
                   6892:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6893:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6894:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6895:        continue;
1.220     brouard  6896: 
1.222     brouard  6897:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6898:      jj1++;
                   6899:      if (cptcovn > 0) {
1.264     brouard  6900:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6901:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6902:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6903:        }
                   6904:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6905:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6906:        }
                   6907:        fprintf(fichtm,"\"</a>");
                   6908:  
1.222     brouard  6909:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6910:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6911:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6912:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6913:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6914:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6915:        }
1.237     brouard  6916:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6917:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6918:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6919:       }
                   6920:        
1.230     brouard  6921:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6922:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6923:        if(invalidvarcomb[k1]){
                   6924:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6925:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6926:         continue;
                   6927:        }
                   6928:      }
                   6929:      /* aij, bij */
1.259     brouard  6930:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6931: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6932:      /* Pij */
1.241     brouard  6933:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6934: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6935:      /* Quasi-incidences */
                   6936:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6937:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6938:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6939: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6940: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  6941:      /* Survival functions (period) in state j */
                   6942:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  6943:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6944: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  6945:      }
                   6946:      /* State specific survival functions (period) */
                   6947:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  6948:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
                   6949:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  6950:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  6951:      }
1.288     brouard  6952:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  6953:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6954:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6955: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  6956:      }
                   6957:      if(backcast==1){
1.288     brouard  6958:        /* Backward prevalence in each health state */
1.222     brouard  6959:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  6960:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  6961: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  6962:        }
1.217     brouard  6963:      }
1.222     brouard  6964:      if(prevfcast==1){
1.288     brouard  6965:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  6966:        for(cpt=1; cpt<=nlstate;cpt++){
1.288     brouard  6967:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.273     brouard  6968: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateproj1, dateproj2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  6969:        }
                   6970:      }
1.268     brouard  6971:      if(backcast==1){
                   6972:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   6973:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  6974:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   6975:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   6976:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   6977: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   6978:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  6979:        }
                   6980:      }
1.220     brouard  6981:         
1.222     brouard  6982:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  6983:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   6984: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  6985:      }
                   6986:      /* } /\* end i1 *\/ */
                   6987:    }/* End k1 */
                   6988:    fprintf(fichtm,"</ul>");
1.126     brouard  6989: 
1.222     brouard  6990:    fprintf(fichtm,"\
1.126     brouard  6991: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  6992:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  6993:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  6994: But because parameters are usually highly correlated (a higher incidence of disability \
                   6995: and a higher incidence of recovery can give very close observed transition) it might \
                   6996: be very useful to look not only at linear confidence intervals estimated from the \
                   6997: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   6998: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   6999: covariance matrix of the one-step probabilities. \
                   7000: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  7001: 
1.222     brouard  7002:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   7003:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   7004:    fprintf(fichtm,"\
1.126     brouard  7005:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7006:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  7007: 
1.222     brouard  7008:    fprintf(fichtm,"\
1.126     brouard  7009:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7010:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7011:    fprintf(fichtm,"\
1.126     brouard  7012:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7013:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7014:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7015:    fprintf(fichtm,"\
1.126     brouard  7016:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7017:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7018:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7019:    fprintf(fichtm,"\
1.288     brouard  7020:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7021:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7022:    fprintf(fichtm,"\
1.128     brouard  7023:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7024:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7025:    fprintf(fichtm,"\
1.288     brouard  7026:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7027:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7028: 
                   7029: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7030: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7031: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7032: /*     <br>",fileres,fileres,fileres,fileres); */
                   7033: /*  else  */
                   7034: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7035:    fflush(fichtm);
                   7036:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7037: 
1.225     brouard  7038:    m=pow(2,cptcoveff);
1.222     brouard  7039:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7040: 
1.222     brouard  7041:    jj1=0;
1.237     brouard  7042: 
1.241     brouard  7043:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7044:    for(k1=1; k1<=m;k1++){
1.253     brouard  7045:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7046:        continue;
1.222     brouard  7047:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7048:      jj1++;
1.126     brouard  7049:      if (cptcovn > 0) {
                   7050:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7051:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7052:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7053:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7054:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7055:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7056:       }
                   7057: 
1.126     brouard  7058:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7059: 
1.222     brouard  7060:        if(invalidvarcomb[k1]){
                   7061:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7062:         continue;
                   7063:        }
1.126     brouard  7064:      }
                   7065:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7066:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7067: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7068: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7069:      }
                   7070:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7071: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7072: true period expectancies (those weighted with period prevalences are also\
                   7073:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7074:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7075: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7076:      /* } /\* end i1 *\/ */
                   7077:    }/* End k1 */
1.241     brouard  7078:   }/* End nres */
1.222     brouard  7079:    fprintf(fichtm,"</ul>");
                   7080:    fflush(fichtm);
1.126     brouard  7081: }
                   7082: 
                   7083: /******************* Gnuplot file **************/
1.270     brouard  7084: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int backcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7085: 
                   7086:   char dirfileres[132],optfileres[132];
1.264     brouard  7087:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7088:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7089:   int lv=0, vlv=0, kl=0;
1.130     brouard  7090:   int ng=0;
1.201     brouard  7091:   int vpopbased;
1.223     brouard  7092:   int ioffset; /* variable offset for columns */
1.270     brouard  7093:   int iyearc=1; /* variable column for year of projection  */
                   7094:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7095:   int nres=0; /* Index of resultline */
1.266     brouard  7096:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7097: 
1.126     brouard  7098: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7099: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7100: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7101: /*   } */
                   7102: 
                   7103:   /*#ifdef windows */
                   7104:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7105:   /*#endif */
1.225     brouard  7106:   m=pow(2,cptcoveff);
1.126     brouard  7107: 
1.274     brouard  7108:   /* diagram of the model */
                   7109:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7110:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7111:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7112:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7113: 
                   7114:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7115:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7116:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7117:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7118:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7119:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7120:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7121: 
1.202     brouard  7122:   /* Contribution to likelihood */
                   7123:   /* Plot the probability implied in the likelihood */
1.223     brouard  7124:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7125:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7126:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7127:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7128: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7129:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7130: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7131:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7132:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7133:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7134:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7135:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7136:   for (i=1; i<= nlstate ; i ++) {
                   7137:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7138:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7139:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7140:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7141:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7142:     }
                   7143:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7144:   }
                   7145:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7146:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7147:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7148:   fprintf(ficgp,"\nset out;unset log\n");
                   7149:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7150: 
1.126     brouard  7151:   strcpy(dirfileres,optionfilefiname);
                   7152:   strcpy(optfileres,"vpl");
1.223     brouard  7153:   /* 1eme*/
1.238     brouard  7154:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7155:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7156:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7157:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7158:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7159:          continue;
                   7160:        /* We are interested in selected combination by the resultline */
1.246     brouard  7161:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7162:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7163:        strcpy(gplotlabel,"(");
1.238     brouard  7164:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7165:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7166:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7167:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7168:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7169:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7170:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7171:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7172:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7173:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7174:        }
                   7175:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7176:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7177:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7178:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7179:        }
                   7180:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7181:        /* printf("\n#\n"); */
1.238     brouard  7182:        fprintf(ficgp,"\n#\n");
                   7183:        if(invalidvarcomb[k1]){
1.260     brouard  7184:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7185:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7186:          continue;
                   7187:        }
1.235     brouard  7188:       
1.241     brouard  7189:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7190:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7191:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7192:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7193:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7194:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7195:       /* k1-1 error should be nres-1*/
1.238     brouard  7196:        for (i=1; i<= nlstate ; i ++) {
                   7197:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7198:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7199:        }
1.288     brouard  7200:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7201:        for (i=1; i<= nlstate ; i ++) {
                   7202:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7203:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7204:        } 
1.260     brouard  7205:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7206:        for (i=1; i<= nlstate ; i ++) {
                   7207:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7208:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7209:        }  
1.265     brouard  7210:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7211:        
                   7212:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7213:         if(cptcoveff ==0){
1.271     brouard  7214:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7215:        }else{
                   7216:          kl=0;
                   7217:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7218:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7219:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7220:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7221:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7222:            vlv= nbcode[Tvaraff[k]][lv];
                   7223:            kl++;
                   7224:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7225:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7226:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7227:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7228:            if(k==cptcoveff){
                   7229:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7230:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7231:            }else{
                   7232:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7233:              kl++;
                   7234:            }
                   7235:          } /* end covariate */
                   7236:        } /* end if no covariate */
                   7237: 
1.238     brouard  7238:        if(backcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
                   7239:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7240:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7241:          if(cptcoveff ==0){
1.245     brouard  7242:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7243:          }else{
                   7244:            kl=0;
                   7245:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7246:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7247:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7248:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7249:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7250:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7251:              kl++;
1.238     brouard  7252:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7253:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7254:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7255:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7256:              if(k==cptcoveff){
1.245     brouard  7257:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7258:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7259:              }else{
                   7260:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7261:                kl++;
                   7262:              }
                   7263:            } /* end covariate */
                   7264:          } /* end if no covariate */
1.268     brouard  7265:          if(backcast == 1){
                   7266:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7267:            /* k1-1 error should be nres-1*/
                   7268:            for (i=1; i<= nlstate ; i ++) {
                   7269:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7270:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7271:            }
1.271     brouard  7272:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7273:            for (i=1; i<= nlstate ; i ++) {
                   7274:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7275:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7276:            } 
1.276     brouard  7277:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7278:            for (i=1; i<= nlstate ; i ++) {
                   7279:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7280:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7281:            } 
1.274     brouard  7282:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7283:          } /* end if backprojcast */
1.238     brouard  7284:        } /* end if backcast */
1.276     brouard  7285:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7286:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7287:       } /* nres */
1.201     brouard  7288:     } /* k1 */
                   7289:   } /* cpt */
1.235     brouard  7290: 
                   7291:   
1.126     brouard  7292:   /*2 eme*/
1.238     brouard  7293:   for (k1=1; k1<= m ; k1 ++){  
                   7294:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7295:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7296:        continue;
                   7297:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7298:       strcpy(gplotlabel,"(");
1.238     brouard  7299:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7300:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7301:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7302:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7303:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7304:        vlv= nbcode[Tvaraff[k]][lv];
                   7305:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7306:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7307:       }
1.237     brouard  7308:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7309:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7310:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7311:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7312:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7313:       }
1.264     brouard  7314:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7315:       fprintf(ficgp,"\n#\n");
1.223     brouard  7316:       if(invalidvarcomb[k1]){
                   7317:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7318:        continue;
                   7319:       }
1.219     brouard  7320:                        
1.241     brouard  7321:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7322:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7323:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7324:        if(vpopbased==0){
1.238     brouard  7325:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7326:        }else
1.238     brouard  7327:          fprintf(ficgp,"\nreplot ");
                   7328:        for (i=1; i<= nlstate+1 ; i ++) {
                   7329:          k=2*i;
1.261     brouard  7330:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7331:          for (j=1; j<= nlstate+1 ; j ++) {
                   7332:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7333:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7334:          }   
                   7335:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7336:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7337:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7338:          for (j=1; j<= nlstate+1 ; j ++) {
                   7339:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7340:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7341:          }   
                   7342:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7343:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7344:          for (j=1; j<= nlstate+1 ; j ++) {
                   7345:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7346:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7347:          }   
                   7348:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7349:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7350:        } /* state */
                   7351:       } /* vpopbased */
1.264     brouard  7352:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7353:     } /* end nres */
                   7354:   } /* k1 end 2 eme*/
                   7355:        
                   7356:        
                   7357:   /*3eme*/
                   7358:   for (k1=1; k1<= m ; k1 ++){
                   7359:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7360:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7361:        continue;
                   7362: 
                   7363:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7364:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7365:        strcpy(gplotlabel,"(");
1.238     brouard  7366:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7367:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7368:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7369:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7370:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7371:          vlv= nbcode[Tvaraff[k]][lv];
                   7372:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7373:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7374:        }
                   7375:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7376:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7377:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7378:        }       
1.264     brouard  7379:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7380:        fprintf(ficgp,"\n#\n");
                   7381:        if(invalidvarcomb[k1]){
                   7382:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7383:          continue;
                   7384:        }
                   7385:                        
                   7386:        /*       k=2+nlstate*(2*cpt-2); */
                   7387:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7388:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7389:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7390:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7391: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7392:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7393:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7394:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7395:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7396:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7397:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7398:                                
1.238     brouard  7399:        */
                   7400:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7401:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7402:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7403:                                
1.238     brouard  7404:        } 
1.261     brouard  7405:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7406:       }
1.264     brouard  7407:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7408:     } /* end nres */
                   7409:   } /* end kl 3eme */
1.126     brouard  7410:   
1.223     brouard  7411:   /* 4eme */
1.201     brouard  7412:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7413:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7414:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7415:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7416:        continue;
1.238     brouard  7417:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7418:        strcpy(gplotlabel,"(");
1.238     brouard  7419:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7420:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7421:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7422:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7423:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7424:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7425:          vlv= nbcode[Tvaraff[k]][lv];
                   7426:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7427:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7428:        }
                   7429:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7430:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7431:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7432:        }       
1.264     brouard  7433:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7434:        fprintf(ficgp,"\n#\n");
                   7435:        if(invalidvarcomb[k1]){
                   7436:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7437:          continue;
1.223     brouard  7438:        }
1.238     brouard  7439:       
1.241     brouard  7440:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7441:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7442:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7443: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7444:        k=3;
                   7445:        for (i=1; i<= nlstate ; i ++){
                   7446:          if(i==1){
                   7447:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7448:          }else{
                   7449:            fprintf(ficgp,", '' ");
                   7450:          }
                   7451:          l=(nlstate+ndeath)*(i-1)+1;
                   7452:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7453:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7454:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7455:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7456:        } /* nlstate */
1.264     brouard  7457:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7458:       } /* end cpt state*/ 
                   7459:     } /* end nres */
                   7460:   } /* end covariate k1 */  
                   7461: 
1.220     brouard  7462: /* 5eme */
1.201     brouard  7463:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7464:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7465:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7466:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7467:        continue;
1.238     brouard  7468:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7469:        strcpy(gplotlabel,"(");
1.238     brouard  7470:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7471:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7472:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7473:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7474:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7475:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7476:          vlv= nbcode[Tvaraff[k]][lv];
                   7477:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7478:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7479:        }
                   7480:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7481:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7482:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7483:        }       
1.264     brouard  7484:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7485:        fprintf(ficgp,"\n#\n");
                   7486:        if(invalidvarcomb[k1]){
                   7487:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7488:          continue;
                   7489:        }
1.227     brouard  7490:       
1.241     brouard  7491:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7492:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7493:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7494: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7495:        k=3;
                   7496:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7497:          if(j==1)
                   7498:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7499:          else
                   7500:            fprintf(ficgp,", '' ");
                   7501:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7502:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7503:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7504:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7505:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7506:        } /* nlstate */
                   7507:        fprintf(ficgp,", '' ");
                   7508:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7509:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7510:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7511:          if(j < nlstate)
                   7512:            fprintf(ficgp,"$%d +",k+l);
                   7513:          else
                   7514:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7515:        }
1.264     brouard  7516:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7517:       } /* end cpt state*/ 
                   7518:     } /* end covariate */  
                   7519:   } /* end nres */
1.227     brouard  7520:   
1.220     brouard  7521: /* 6eme */
1.202     brouard  7522:   /* CV preval stable (period) for each covariate */
1.237     brouard  7523:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7524:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7525:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7526:       continue;
1.255     brouard  7527:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7528:       strcpy(gplotlabel,"(");      
1.288     brouard  7529:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7530:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7531:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7532:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7533:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7534:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7535:        vlv= nbcode[Tvaraff[k]][lv];
                   7536:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7537:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7538:       }
1.237     brouard  7539:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7540:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7541:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7542:       }        
1.264     brouard  7543:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7544:       fprintf(ficgp,"\n#\n");
1.223     brouard  7545:       if(invalidvarcomb[k1]){
1.227     brouard  7546:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7547:        continue;
1.223     brouard  7548:       }
1.227     brouard  7549:       
1.241     brouard  7550:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7551:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7552:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7553: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7554:       k=3; /* Offset */
1.255     brouard  7555:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7556:        if(i==1)
                   7557:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7558:        else
                   7559:          fprintf(ficgp,", '' ");
1.255     brouard  7560:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7561:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7562:        for (j=2; j<= nlstate ; j ++)
                   7563:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7564:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7565:       } /* nlstate */
1.264     brouard  7566:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7567:     } /* end cpt state*/ 
                   7568:   } /* end covariate */  
1.227     brouard  7569:   
                   7570:   
1.220     brouard  7571: /* 7eme */
1.218     brouard  7572:   if(backcast == 1){
1.288     brouard  7573:     /* CV backward prevalence  for each covariate */
1.237     brouard  7574:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7575:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7576:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7577:        continue;
1.268     brouard  7578:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7579:        strcpy(gplotlabel,"(");      
1.288     brouard  7580:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7581:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7582:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7583:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7584:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7585:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7586:          vlv= nbcode[Tvaraff[k]][lv];
                   7587:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7588:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7589:        }
1.237     brouard  7590:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7591:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7592:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7593:        }       
1.264     brouard  7594:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7595:        fprintf(ficgp,"\n#\n");
                   7596:        if(invalidvarcomb[k1]){
                   7597:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7598:          continue;
                   7599:        }
                   7600:        
1.241     brouard  7601:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7602:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7603:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7604: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7605:        k=3; /* Offset */
1.268     brouard  7606:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7607:          if(i==1)
                   7608:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7609:          else
                   7610:            fprintf(ficgp,", '' ");
                   7611:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7612:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7613:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7614:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7615:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7616:          /* for (j=2; j<= nlstate ; j ++) */
                   7617:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7618:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7619:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7620:        } /* nlstate */
1.264     brouard  7621:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7622:       } /* end cpt state*/ 
                   7623:     } /* end covariate */  
                   7624:   } /* End if backcast */
                   7625:   
1.223     brouard  7626:   /* 8eme */
1.218     brouard  7627:   if(prevfcast==1){
1.288     brouard  7628:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7629:     
1.237     brouard  7630:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7631:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7632:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7633:        continue;
1.211     brouard  7634:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7635:        strcpy(gplotlabel,"(");      
1.288     brouard  7636:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7637:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7638:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7639:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7640:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7641:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7642:          vlv= nbcode[Tvaraff[k]][lv];
                   7643:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7644:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7645:        }
1.237     brouard  7646:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7647:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7648:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7649:        }       
1.264     brouard  7650:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7651:        fprintf(ficgp,"\n#\n");
                   7652:        if(invalidvarcomb[k1]){
                   7653:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7654:          continue;
                   7655:        }
                   7656:        
                   7657:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7658:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7659:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7660:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7661: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7662: 
                   7663:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7664:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7665:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7666:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7667:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7668:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7669:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7670:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7671:          if(i==istart){
1.227     brouard  7672:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7673:          }else{
                   7674:            fprintf(ficgp,",\\\n '' ");
                   7675:          }
                   7676:          if(cptcoveff ==0){ /* No covariate */
                   7677:            ioffset=2; /* Age is in 2 */
                   7678:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7679:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7680:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7681:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7682:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7683:            if(i==nlstate+1){
1.270     brouard  7684:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7685:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7686:              fprintf(ficgp,",\\\n '' ");
                   7687:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7688:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7689:                     offyear,                           \
1.268     brouard  7690:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7691:            }else
1.227     brouard  7692:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7693:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7694:          }else{ /* more than 2 covariates */
1.270     brouard  7695:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7696:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7697:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7698:            iyearc=ioffset-1;
                   7699:            iagec=ioffset;
1.227     brouard  7700:            fprintf(ficgp," u %d:(",ioffset); 
                   7701:            kl=0;
                   7702:            strcpy(gplotcondition,"(");
                   7703:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7704:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7705:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7706:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7707:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7708:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7709:              kl++;
                   7710:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7711:              kl++;
                   7712:              if(k <cptcoveff && cptcoveff>1)
                   7713:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7714:            }
                   7715:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7716:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7717:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7718:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7719:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7720:            if(i==nlstate+1){
1.270     brouard  7721:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7722:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7723:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7724:              fprintf(ficgp," u %d:(",iagec); 
                   7725:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7726:                      iyearc, iagec, offyear,                           \
                   7727:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7728: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7729:            }else{
                   7730:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7731:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7732:            }
                   7733:          } /* end if covariate */
                   7734:        } /* nlstate */
1.264     brouard  7735:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7736:       } /* end cpt state*/
                   7737:     } /* end covariate */
                   7738:   } /* End if prevfcast */
1.227     brouard  7739:   
1.268     brouard  7740:   if(backcast==1){
                   7741:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7742:     
                   7743:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7744:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7745:       if(m != 1 && TKresult[nres]!= k1)
                   7746:        continue;
                   7747:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7748:        strcpy(gplotlabel,"(");      
                   7749:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7750:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7751:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7752:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7753:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7754:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7755:          vlv= nbcode[Tvaraff[k]][lv];
                   7756:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7757:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7758:        }
                   7759:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7760:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7761:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7762:        }       
                   7763:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7764:        fprintf(ficgp,"\n#\n");
                   7765:        if(invalidvarcomb[k1]){
                   7766:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7767:          continue;
                   7768:        }
                   7769:        
                   7770:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7771:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7772:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7773:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7774: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7775: 
                   7776:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7777:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7778:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7779:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7780:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7781:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7782:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7783:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7784:          if(i==istart){
                   7785:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7786:          }else{
                   7787:            fprintf(ficgp,",\\\n '' ");
                   7788:          }
                   7789:          if(cptcoveff ==0){ /* No covariate */
                   7790:            ioffset=2; /* Age is in 2 */
                   7791:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7792:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7793:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7794:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7795:            fprintf(ficgp," u %d:(", ioffset); 
                   7796:            if(i==nlstate+1){
1.270     brouard  7797:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7798:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7799:              fprintf(ficgp,",\\\n '' ");
                   7800:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7801:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7802:                     offbyear,                          \
                   7803:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7804:            }else
                   7805:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7806:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7807:          }else{ /* more than 2 covariates */
1.270     brouard  7808:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7809:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7810:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7811:            iyearc=ioffset-1;
                   7812:            iagec=ioffset;
1.268     brouard  7813:            fprintf(ficgp," u %d:(",ioffset); 
                   7814:            kl=0;
                   7815:            strcpy(gplotcondition,"(");
                   7816:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7817:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7818:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7819:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7820:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7821:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7822:              kl++;
                   7823:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7824:              kl++;
                   7825:              if(k <cptcoveff && cptcoveff>1)
                   7826:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7827:            }
                   7828:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7829:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7830:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7831:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7832:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7833:            if(i==nlstate+1){
1.270     brouard  7834:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7835:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7836:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7837:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7838:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7839:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7840:                      iyearc,iagec,offbyear,                            \
                   7841:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7842: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7843:            }else{
                   7844:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7845:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7846:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7847:            }
                   7848:          } /* end if covariate */
                   7849:        } /* nlstate */
                   7850:        fprintf(ficgp,"\nset out; unset label;\n");
                   7851:       } /* end cpt state*/
                   7852:     } /* end covariate */
                   7853:   } /* End if backcast */
                   7854:   
1.227     brouard  7855:   
1.238     brouard  7856:   /* 9eme writing MLE parameters */
                   7857:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7858:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7859:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7860:     for(k=1; k <=(nlstate+ndeath); k++){
                   7861:       if (k != i) {
1.227     brouard  7862:        fprintf(ficgp,"#   current state %d\n",k);
                   7863:        for(j=1; j <=ncovmodel; j++){
                   7864:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7865:          jk++; 
                   7866:        }
                   7867:        fprintf(ficgp,"\n");
1.126     brouard  7868:       }
                   7869:     }
1.223     brouard  7870:   }
1.187     brouard  7871:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7872:   
1.145     brouard  7873:   /*goto avoid;*/
1.238     brouard  7874:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7875:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7876:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7877:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7878:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7879:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7880:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7881:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7882:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7883:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7884:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7885:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7886:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7887:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7888:   fprintf(ficgp,"#\n");
1.223     brouard  7889:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7890:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7891:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7892:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7893:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7894:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7895:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7896:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7897:        continue;
1.264     brouard  7898:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7899:       strcpy(gplotlabel,"(");
1.276     brouard  7900:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  7901:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7902:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7903:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7904:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7905:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7906:        vlv= nbcode[Tvaraff[k]][lv];
                   7907:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7908:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7909:       }
1.237     brouard  7910:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7911:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7912:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7913:       }        
1.264     brouard  7914:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7915:       fprintf(ficgp,"\n#\n");
1.264     brouard  7916:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  7917:       fprintf(ficgp,"\nset key outside ");
                   7918:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   7919:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7920:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7921:       if (ng==1){
                   7922:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7923:        fprintf(ficgp,"\nunset log y");
                   7924:       }else if (ng==2){
                   7925:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7926:        fprintf(ficgp,"\nset log y");
                   7927:       }else if (ng==3){
                   7928:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7929:        fprintf(ficgp,"\nset log y");
                   7930:       }else
                   7931:        fprintf(ficgp,"\nunset title ");
                   7932:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7933:       i=1;
                   7934:       for(k2=1; k2<=nlstate; k2++) {
                   7935:        k3=i;
                   7936:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7937:          if (k != k2){
                   7938:            switch( ng) {
                   7939:            case 1:
                   7940:              if(nagesqr==0)
                   7941:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   7942:              else /* nagesqr =1 */
                   7943:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7944:              break;
                   7945:            case 2: /* ng=2 */
                   7946:              if(nagesqr==0)
                   7947:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   7948:              else /* nagesqr =1 */
                   7949:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   7950:              break;
                   7951:            case 3:
                   7952:              if(nagesqr==0)
                   7953:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   7954:              else /* nagesqr =1 */
                   7955:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   7956:              break;
                   7957:            }
                   7958:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  7959:            ijp=1; /* product no age */
                   7960:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   7961:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  7962:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  7963:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7964:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   7965:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   7966:                    if(DummyV[j]==0){
                   7967:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   7968:                    }else{ /* quantitative */
                   7969:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   7970:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   7971:                    }
                   7972:                    ij++;
1.237     brouard  7973:                  }
1.268     brouard  7974:                } 
                   7975:              }else if(cptcovprod >0){
                   7976:                if(j==Tprod[ijp]) { /* */ 
                   7977:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   7978:                  if(ijp <=cptcovprod) { /* Product */
                   7979:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   7980:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   7981:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   7982:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   7983:                      }else{ /* Vn is dummy and Vm is quanti */
                   7984:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   7985:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7986:                      }
                   7987:                    }else{ /* Vn*Vm Vn is quanti */
                   7988:                      if(DummyV[Tvard[ijp][2]]==0){
                   7989:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   7990:                      }else{ /* Both quanti */
                   7991:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   7992:                      }
1.237     brouard  7993:                    }
1.268     brouard  7994:                    ijp++;
1.237     brouard  7995:                  }
1.268     brouard  7996:                } /* end Tprod */
1.237     brouard  7997:              } else{  /* simple covariate */
1.264     brouard  7998:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  7999:                if(Dummy[j]==0){
                   8000:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   8001:                }else{ /* quantitative */
                   8002:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  8003:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  8004:                }
1.237     brouard  8005:              } /* end simple */
                   8006:            } /* end j */
1.223     brouard  8007:          }else{
                   8008:            i=i-ncovmodel;
                   8009:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8010:              fprintf(ficgp," (1.");
                   8011:          }
1.227     brouard  8012:          
1.223     brouard  8013:          if(ng != 1){
                   8014:            fprintf(ficgp,")/(1");
1.227     brouard  8015:            
1.264     brouard  8016:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8017:              if(nagesqr==0)
1.264     brouard  8018:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8019:              else /* nagesqr =1 */
1.264     brouard  8020:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8021:               
1.223     brouard  8022:              ij=1;
                   8023:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8024:                 if(cptcovage >0){ 
                   8025:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8026:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8027:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8028:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8029:                       ij++;
                   8030:                     }
                   8031:                   }
                   8032:                 }else
                   8033:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8034:              }
                   8035:              fprintf(ficgp,")");
                   8036:            }
                   8037:            fprintf(ficgp,")");
                   8038:            if(ng ==2)
1.276     brouard  8039:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8040:            else /* ng= 3 */
1.276     brouard  8041:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8042:          }else{ /* end ng <> 1 */
                   8043:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8044:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8045:          }
                   8046:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8047:            fprintf(ficgp,",");
                   8048:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8049:            fprintf(ficgp,",");
                   8050:          i=i+ncovmodel;
                   8051:        } /* end k */
                   8052:       } /* end k2 */
1.276     brouard  8053:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8054:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8055:     } /* end k1 */
1.223     brouard  8056:   } /* end ng */
                   8057:   /* avoid: */
                   8058:   fflush(ficgp); 
1.126     brouard  8059: }  /* end gnuplot */
                   8060: 
                   8061: 
                   8062: /*************** Moving average **************/
1.219     brouard  8063: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8064:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8065:    
1.222     brouard  8066:    int i, cpt, cptcod;
                   8067:    int modcovmax =1;
                   8068:    int mobilavrange, mob;
                   8069:    int iage=0;
1.288     brouard  8070:    int firstA1=0, firstA2=0;
1.222     brouard  8071: 
1.266     brouard  8072:    double sum=0., sumr=0.;
1.222     brouard  8073:    double age;
1.266     brouard  8074:    double *sumnewp, *sumnewm, *sumnewmr;
                   8075:    double *agemingood, *agemaxgood; 
                   8076:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8077:   
                   8078:   
1.278     brouard  8079:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8080:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8081: 
                   8082:    sumnewp = vector(1,ncovcombmax);
                   8083:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8084:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8085:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8086:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8087:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8088:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8089: 
                   8090:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8091:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8092:      sumnewp[cptcod]=0.;
1.266     brouard  8093:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8094:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8095:    }
                   8096:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8097:   
1.266     brouard  8098:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8099:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8100:      else mobilavrange=mobilav;
                   8101:      for (age=bage; age<=fage; age++)
                   8102:        for (i=1; i<=nlstate;i++)
                   8103:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8104:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8105:      /* We keep the original values on the extreme ages bage, fage and for 
                   8106:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8107:        we use a 5 terms etc. until the borders are no more concerned. 
                   8108:      */ 
                   8109:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8110:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8111:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8112:           sumnewm[cptcod]=0.;
                   8113:           for (i=1; i<=nlstate;i++){
1.222     brouard  8114:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8115:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8116:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8117:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8118:             }
                   8119:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8120:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8121:           } /* end i */
                   8122:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8123:         } /* end cptcod */
1.222     brouard  8124:        }/* end age */
                   8125:      }/* end mob */
1.266     brouard  8126:    }else{
                   8127:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8128:      return -1;
1.266     brouard  8129:    }
                   8130: 
                   8131:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8132:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8133:      if(invalidvarcomb[cptcod]){
                   8134:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8135:        continue;
                   8136:      }
1.219     brouard  8137: 
1.266     brouard  8138:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8139:        sumnewm[cptcod]=0.;
                   8140:        sumnewmr[cptcod]=0.;
                   8141:        for (i=1; i<=nlstate;i++){
                   8142:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8143:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8144:        }
                   8145:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8146:         agemingoodr[cptcod]=age;
                   8147:        }
                   8148:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8149:           agemingood[cptcod]=age;
                   8150:        }
                   8151:      } /* age */
                   8152:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8153:        sumnewm[cptcod]=0.;
1.266     brouard  8154:        sumnewmr[cptcod]=0.;
1.222     brouard  8155:        for (i=1; i<=nlstate;i++){
                   8156:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8157:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8158:        }
                   8159:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8160:         agemaxgoodr[cptcod]=age;
1.222     brouard  8161:        }
                   8162:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8163:         agemaxgood[cptcod]=age;
                   8164:        }
                   8165:      } /* age */
                   8166:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8167:      /* but they will change */
1.288     brouard  8168:      firstA1=0;firstA2=0;
1.266     brouard  8169:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8170:        sumnewm[cptcod]=0.;
                   8171:        sumnewmr[cptcod]=0.;
                   8172:        for (i=1; i<=nlstate;i++){
                   8173:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8174:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8175:        }
                   8176:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8177:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8178:           agemaxgoodr[cptcod]=age;  /* age min */
                   8179:           for (i=1; i<=nlstate;i++)
                   8180:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8181:         }else{ /* bad we change the value with the values of good ages */
                   8182:           for (i=1; i<=nlstate;i++){
                   8183:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8184:           } /* i */
                   8185:         } /* end bad */
                   8186:        }else{
                   8187:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8188:           agemaxgood[cptcod]=age;
                   8189:         }else{ /* bad we change the value with the values of good ages */
                   8190:           for (i=1; i<=nlstate;i++){
                   8191:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8192:           } /* i */
                   8193:         } /* end bad */
                   8194:        }/* end else */
                   8195:        sum=0.;sumr=0.;
                   8196:        for (i=1; i<=nlstate;i++){
                   8197:         sum+=mobaverage[(int)age][i][cptcod];
                   8198:         sumr+=probs[(int)age][i][cptcod];
                   8199:        }
                   8200:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8201:         if(!firstA1){
                   8202:           firstA1=1;
                   8203:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8204:         }
                   8205:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8206:        } /* end bad */
                   8207:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8208:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8209:         if(!firstA2){
                   8210:           firstA2=1;
                   8211:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8212:         }
                   8213:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8214:        } /* end bad */
                   8215:      }/* age */
1.266     brouard  8216: 
                   8217:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8218:        sumnewm[cptcod]=0.;
1.266     brouard  8219:        sumnewmr[cptcod]=0.;
1.222     brouard  8220:        for (i=1; i<=nlstate;i++){
                   8221:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8222:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8223:        } 
                   8224:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8225:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8226:           agemingoodr[cptcod]=age;
                   8227:           for (i=1; i<=nlstate;i++)
                   8228:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8229:         }else{ /* bad we change the value with the values of good ages */
                   8230:           for (i=1; i<=nlstate;i++){
                   8231:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8232:           } /* i */
                   8233:         } /* end bad */
                   8234:        }else{
                   8235:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8236:           agemingood[cptcod]=age;
                   8237:         }else{ /* bad */
                   8238:           for (i=1; i<=nlstate;i++){
                   8239:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8240:           } /* i */
                   8241:         } /* end bad */
                   8242:        }/* end else */
                   8243:        sum=0.;sumr=0.;
                   8244:        for (i=1; i<=nlstate;i++){
                   8245:         sum+=mobaverage[(int)age][i][cptcod];
                   8246:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8247:        }
1.266     brouard  8248:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8249:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8250:        } /* end bad */
                   8251:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8252:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8253:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8254:        } /* end bad */
                   8255:      }/* age */
1.266     brouard  8256: 
1.222     brouard  8257:                
                   8258:      for (age=bage; age<=fage; age++){
1.235     brouard  8259:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8260:        sumnewp[cptcod]=0.;
                   8261:        sumnewm[cptcod]=0.;
                   8262:        for (i=1; i<=nlstate;i++){
                   8263:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8264:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8265:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8266:        }
                   8267:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8268:      }
                   8269:      /* printf("\n"); */
                   8270:      /* } */
1.266     brouard  8271: 
1.222     brouard  8272:      /* brutal averaging */
1.266     brouard  8273:      /* for (i=1; i<=nlstate;i++){ */
                   8274:      /*   for (age=1; age<=bage; age++){ */
                   8275:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8276:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8277:      /*   }     */
                   8278:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8279:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8280:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8281:      /*   } */
                   8282:      /* } /\* end i status *\/ */
                   8283:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8284:      /*   for (age=1; age<=AGESUP; age++){ */
                   8285:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8286:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8287:      /*   } */
                   8288:      /* } */
1.222     brouard  8289:    }/* end cptcod */
1.266     brouard  8290:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8291:    free_vector(agemaxgood,1, ncovcombmax);
                   8292:    free_vector(agemingood,1, ncovcombmax);
                   8293:    free_vector(agemingoodr,1, ncovcombmax);
                   8294:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8295:    free_vector(sumnewm,1, ncovcombmax);
                   8296:    free_vector(sumnewp,1, ncovcombmax);
                   8297:    return 0;
                   8298:  }/* End movingaverage */
1.218     brouard  8299:  
1.126     brouard  8300: 
                   8301: /************** Forecasting ******************/
1.269     brouard  8302:  void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
1.126     brouard  8303:   /* proj1, year, month, day of starting projection 
                   8304:      agemin, agemax range of age
                   8305:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8306:      anproj2 year of en of projection (same day and month as proj1).
                   8307:   */
1.267     brouard  8308:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8309:   double agec; /* generic age */
                   8310:   double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
                   8311:   double *popeffectif,*popcount;
                   8312:   double ***p3mat;
1.218     brouard  8313:   /* double ***mobaverage; */
1.126     brouard  8314:   char fileresf[FILENAMELENGTH];
                   8315: 
                   8316:   agelim=AGESUP;
1.211     brouard  8317:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8318:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8319:      We still use firstpass and lastpass as another selection.
                   8320:   */
1.214     brouard  8321:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8322:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8323:  
1.201     brouard  8324:   strcpy(fileresf,"F_"); 
                   8325:   strcat(fileresf,fileresu);
1.126     brouard  8326:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8327:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8328:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8329:   }
1.235     brouard  8330:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8331:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8332: 
1.225     brouard  8333:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8334: 
                   8335: 
                   8336:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8337:   if (stepm<=12) stepsize=1;
                   8338:   if(estepm < stepm){
                   8339:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8340:   }
1.270     brouard  8341:   else{
                   8342:     hstepm=estepm;   
                   8343:   }
                   8344:   if(estepm > stepm){ /* Yes every two year */
                   8345:     stepsize=2;
                   8346:   }
1.126     brouard  8347: 
                   8348:   hstepm=hstepm/stepm; 
                   8349:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8350:                                fractional in yp1 */
                   8351:   anprojmean=yp;
                   8352:   yp2=modf((yp1*12),&yp);
                   8353:   mprojmean=yp;
                   8354:   yp1=modf((yp2*30.5),&yp);
                   8355:   jprojmean=yp;
                   8356:   if(jprojmean==0) jprojmean=1;
                   8357:   if(mprojmean==0) jprojmean=1;
                   8358: 
1.227     brouard  8359:   i1=pow(2,cptcoveff);
1.126     brouard  8360:   if (cptcovn < 1){i1=1;}
                   8361:   
                   8362:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
                   8363:   
                   8364:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8365:   
1.126     brouard  8366: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8367:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8368:   for(k=1; k<=i1;k++){
1.253     brouard  8369:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8370:       continue;
1.227     brouard  8371:     if(invalidvarcomb[k]){
                   8372:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8373:       continue;
                   8374:     }
                   8375:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8376:     for(j=1;j<=cptcoveff;j++) {
                   8377:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8378:     }
1.235     brouard  8379:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8380:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8381:     }
1.227     brouard  8382:     fprintf(ficresf," yearproj age");
                   8383:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8384:       for(i=1; i<=nlstate;i++)               
                   8385:        fprintf(ficresf," p%d%d",i,j);
                   8386:       fprintf(ficresf," wp.%d",j);
                   8387:     }
                   8388:     for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {
                   8389:       fprintf(ficresf,"\n");
                   8390:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
1.270     brouard  8391:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8392:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8393:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8394:        nhstepm = nhstepm/hstepm; 
                   8395:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8396:        oldm=oldms;savm=savms;
1.268     brouard  8397:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8398:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8399:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8400:        for (h=0; h<=nhstepm; h++){
                   8401:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8402:            break;
                   8403:          }
                   8404:        }
                   8405:        fprintf(ficresf,"\n");
                   8406:        for(j=1;j<=cptcoveff;j++) 
                   8407:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8408:        fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
                   8409:        
                   8410:        for(j=1; j<=nlstate+ndeath;j++) {
                   8411:          ppij=0.;
                   8412:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8413:            if (mobilav>=1)
                   8414:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8415:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8416:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8417:            }
1.268     brouard  8418:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8419:          } /* end i */
                   8420:          fprintf(ficresf," %.3f", ppij);
                   8421:        }/* end j */
1.227     brouard  8422:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8423:       } /* end agec */
1.266     brouard  8424:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8425:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8426:     } /* end yearp */
                   8427:   } /* end  k */
1.219     brouard  8428:        
1.126     brouard  8429:   fclose(ficresf);
1.215     brouard  8430:   printf("End of Computing forecasting \n");
                   8431:   fprintf(ficlog,"End of Computing forecasting\n");
                   8432: 
1.126     brouard  8433: }
                   8434: 
1.269     brouard  8435: /************** Back Forecasting ******************/
                   8436:  void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){
1.267     brouard  8437:   /* back1, year, month, day of starting backection
                   8438:      agemin, agemax range of age
                   8439:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8440:      anback2 year of end of backprojection (same day and month as back1).
                   8441:      prevacurrent and prev are prevalences.
1.267     brouard  8442:   */
                   8443:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8444:   double agec; /* generic age */
1.268     brouard  8445:   double agelim, ppij, ppi, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
1.267     brouard  8446:   double *popeffectif,*popcount;
                   8447:   double ***p3mat;
                   8448:   /* double ***mobaverage; */
                   8449:   char fileresfb[FILENAMELENGTH];
                   8450:  
1.268     brouard  8451:   agelim=AGEINF;
1.267     brouard  8452:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8453:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8454:      We still use firstpass and lastpass as another selection.
                   8455:   */
                   8456:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8457:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8458: 
                   8459:   /*Do we need to compute prevalence again?*/
                   8460: 
                   8461:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8462:   
                   8463:   strcpy(fileresfb,"FB_");
                   8464:   strcat(fileresfb,fileresu);
                   8465:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8466:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8467:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8468:   }
                   8469:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8470:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8471:   
                   8472:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8473:   
                   8474:    
                   8475:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8476:   if (stepm<=12) stepsize=1;
                   8477:   if(estepm < stepm){
                   8478:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8479:   }
1.270     brouard  8480:   else{
                   8481:     hstepm=estepm;   
                   8482:   }
                   8483:   if(estepm >= stepm){ /* Yes every two year */
                   8484:     stepsize=2;
                   8485:   }
1.267     brouard  8486:   
                   8487:   hstepm=hstepm/stepm;
                   8488:   yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                   8489:                                fractional in yp1 */
                   8490:   anprojmean=yp;
                   8491:   yp2=modf((yp1*12),&yp);
                   8492:   mprojmean=yp;
                   8493:   yp1=modf((yp2*30.5),&yp);
                   8494:   jprojmean=yp;
                   8495:   if(jprojmean==0) jprojmean=1;
                   8496:   if(mprojmean==0) jprojmean=1;
                   8497:   
                   8498:   i1=pow(2,cptcoveff);
                   8499:   if (cptcovn < 1){i1=1;}
                   8500:   
                   8501:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.268     brouard  8502:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8503:   
                   8504:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8505:   
                   8506:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8507:   for(k=1; k<=i1;k++){
                   8508:     if(i1 != 1 && TKresult[nres]!= k)
                   8509:       continue;
                   8510:     if(invalidvarcomb[k]){
                   8511:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8512:       continue;
                   8513:     }
1.268     brouard  8514:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8515:     for(j=1;j<=cptcoveff;j++) {
                   8516:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8517:     }
                   8518:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8519:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8520:     }
                   8521:     fprintf(ficresfb," yearbproj age");
                   8522:     for(j=1; j<=nlstate+ndeath;j++){
                   8523:       for(i=1; i<=nlstate;i++)
1.268     brouard  8524:        fprintf(ficresfb," b%d%d",i,j);
                   8525:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8526:     }
                   8527:     for (yearp=0; yearp>=(anback2-anback1);yearp -=stepsize) {
                   8528:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8529:       fprintf(ficresfb,"\n");
                   8530:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp);
1.273     brouard  8531:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8532:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8533:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8534:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8535:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8536:        nhstepm = nhstepm/hstepm;
                   8537:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8538:        oldm=oldms;savm=savms;
1.268     brouard  8539:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8540:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8541:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8542:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8543:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8544:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8545:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8546:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8547:            break;
                   8548:          }
                   8549:        }
                   8550:        fprintf(ficresfb,"\n");
                   8551:        for(j=1;j<=cptcoveff;j++)
                   8552:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8553:        fprintf(ficresfb,"%.f %.f ",anback1+yearp,agec-h*hstepm/YEARM*stepm);
                   8554:        for(i=1; i<=nlstate+ndeath;i++) {
                   8555:          ppij=0.;ppi=0.;
                   8556:          for(j=1; j<=nlstate;j++) {
                   8557:            /* if (mobilav==1) */
1.269     brouard  8558:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8559:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8560:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8561:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8562:              /* else { */
                   8563:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8564:              /* } */
1.268     brouard  8565:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8566:          } /* end j */
                   8567:          if(ppi <0.99){
                   8568:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8569:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8570:          }
                   8571:          fprintf(ficresfb," %.3f", ppij);
                   8572:        }/* end j */
1.267     brouard  8573:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8574:       } /* end agec */
                   8575:     } /* end yearp */
                   8576:   } /* end k */
1.217     brouard  8577:   
1.267     brouard  8578:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8579:   
1.267     brouard  8580:   fclose(ficresfb);
                   8581:   printf("End of Computing Back forecasting \n");
                   8582:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8583:        
1.267     brouard  8584: }
1.217     brouard  8585: 
1.269     brouard  8586: /* Variance of prevalence limit: varprlim */
                   8587:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8588:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8589:  
                   8590:    char fileresvpl[FILENAMELENGTH];  
                   8591:    FILE *ficresvpl;
                   8592:    double **oldm, **savm;
                   8593:    double **varpl; /* Variances of prevalence limits by age */   
                   8594:    int i1, k, nres, j ;
                   8595:    
                   8596:     strcpy(fileresvpl,"VPL_");
                   8597:     strcat(fileresvpl,fileresu);
                   8598:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8599:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8600:       exit(0);
                   8601:     }
1.288     brouard  8602:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8603:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8604:     
                   8605:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8606:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8607:     
                   8608:     i1=pow(2,cptcoveff);
                   8609:     if (cptcovn < 1){i1=1;}
                   8610: 
                   8611:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8612:     for(k=1; k<=i1;k++){
                   8613:       if(i1 != 1 && TKresult[nres]!= k)
                   8614:        continue;
                   8615:       fprintf(ficresvpl,"\n#****** ");
                   8616:       printf("\n#****** ");
                   8617:       fprintf(ficlog,"\n#****** ");
                   8618:       for(j=1;j<=cptcoveff;j++) {
                   8619:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8620:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8621:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8622:       }
                   8623:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8624:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8625:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8626:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8627:       }        
                   8628:       fprintf(ficresvpl,"******\n");
                   8629:       printf("******\n");
                   8630:       fprintf(ficlog,"******\n");
                   8631:       
                   8632:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8633:       oldm=oldms;savm=savms;
                   8634:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8635:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8636:       /*}*/
                   8637:     }
                   8638:     
                   8639:     fclose(ficresvpl);
1.288     brouard  8640:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   8641:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  8642: 
                   8643:  }
                   8644: /* Variance of back prevalence: varbprlim */
                   8645:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8646:       /*------- Variance of back (stable) prevalence------*/
                   8647: 
                   8648:    char fileresvbl[FILENAMELENGTH];  
                   8649:    FILE  *ficresvbl;
                   8650: 
                   8651:    double **oldm, **savm;
                   8652:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8653:    int i1, k, nres, j ;
                   8654: 
                   8655:    strcpy(fileresvbl,"VBL_");
                   8656:    strcat(fileresvbl,fileresu);
                   8657:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8658:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8659:      exit(0);
                   8660:    }
                   8661:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8662:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8663:    
                   8664:    
                   8665:    i1=pow(2,cptcoveff);
                   8666:    if (cptcovn < 1){i1=1;}
                   8667:    
                   8668:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8669:      for(k=1; k<=i1;k++){
                   8670:        if(i1 != 1 && TKresult[nres]!= k)
                   8671:         continue;
                   8672:        fprintf(ficresvbl,"\n#****** ");
                   8673:        printf("\n#****** ");
                   8674:        fprintf(ficlog,"\n#****** ");
                   8675:        for(j=1;j<=cptcoveff;j++) {
                   8676:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8677:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8678:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8679:        }
                   8680:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8681:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8682:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8683:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8684:        }
                   8685:        fprintf(ficresvbl,"******\n");
                   8686:        printf("******\n");
                   8687:        fprintf(ficlog,"******\n");
                   8688:        
                   8689:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8690:        oldm=oldms;savm=savms;
                   8691:        
                   8692:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8693:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8694:        /*}*/
                   8695:      }
                   8696:    
                   8697:    fclose(ficresvbl);
                   8698:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8699:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8700: 
                   8701:  } /* End of varbprlim */
                   8702: 
1.126     brouard  8703: /************** Forecasting *****not tested NB*************/
1.227     brouard  8704: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8705:   
1.227     brouard  8706: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8707: /*   int *popage; */
                   8708: /*   double calagedatem, agelim, kk1, kk2; */
                   8709: /*   double *popeffectif,*popcount; */
                   8710: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8711: /*   /\* double ***mobaverage; *\/ */
                   8712: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8713: 
1.227     brouard  8714: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8715: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8716: /*   agelim=AGESUP; */
                   8717: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8718:   
1.227     brouard  8719: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8720:   
                   8721:   
1.227     brouard  8722: /*   strcpy(filerespop,"POP_");  */
                   8723: /*   strcat(filerespop,fileresu); */
                   8724: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8725: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8726: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8727: /*   } */
                   8728: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8729: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8730: 
1.227     brouard  8731: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8732: 
1.227     brouard  8733: /*   /\* if (mobilav!=0) { *\/ */
                   8734: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8735: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8736: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8737: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8738: /*   /\*   } *\/ */
                   8739: /*   /\* } *\/ */
1.126     brouard  8740: 
1.227     brouard  8741: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8742: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8743:   
1.227     brouard  8744: /*   agelim=AGESUP; */
1.126     brouard  8745:   
1.227     brouard  8746: /*   hstepm=1; */
                   8747: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8748:        
1.227     brouard  8749: /*   if (popforecast==1) { */
                   8750: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8751: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8752: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8753: /*     }  */
                   8754: /*     popage=ivector(0,AGESUP); */
                   8755: /*     popeffectif=vector(0,AGESUP); */
                   8756: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8757:     
1.227     brouard  8758: /*     i=1;    */
                   8759: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8760:     
1.227     brouard  8761: /*     imx=i; */
                   8762: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8763: /*   } */
1.218     brouard  8764:   
1.227     brouard  8765: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8766: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8767: /*       k=k+1; */
                   8768: /*       fprintf(ficrespop,"\n#******"); */
                   8769: /*       for(j=1;j<=cptcoveff;j++) { */
                   8770: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8771: /*       } */
                   8772: /*       fprintf(ficrespop,"******\n"); */
                   8773: /*       fprintf(ficrespop,"# Age"); */
                   8774: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8775: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8776:       
1.227     brouard  8777: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8778: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8779:        
1.227     brouard  8780: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8781: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8782: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8783:          
1.227     brouard  8784: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8785: /*       oldm=oldms;savm=savms; */
                   8786: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8787:          
1.227     brouard  8788: /*       for (h=0; h<=nhstepm; h++){ */
                   8789: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8790: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8791: /*         }  */
                   8792: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8793: /*           kk1=0.;kk2=0; */
                   8794: /*           for(i=1; i<=nlstate;i++) {               */
                   8795: /*             if (mobilav==1)  */
                   8796: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8797: /*             else { */
                   8798: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8799: /*             } */
                   8800: /*           } */
                   8801: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8802: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8803: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8804: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8805: /*           } */
                   8806: /*         } */
                   8807: /*         for(i=1; i<=nlstate;i++){ */
                   8808: /*           kk1=0.; */
                   8809: /*           for(j=1; j<=nlstate;j++){ */
                   8810: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8811: /*           } */
                   8812: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8813: /*         } */
1.218     brouard  8814:            
1.227     brouard  8815: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8816: /*           for(j=1; j<=nlstate;j++)  */
                   8817: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8818: /*       } */
                   8819: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8820: /*     } */
                   8821: /*       } */
1.218     brouard  8822:       
1.227     brouard  8823: /*       /\******\/ */
1.218     brouard  8824:       
1.227     brouard  8825: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8826: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8827: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8828: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8829: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8830:          
1.227     brouard  8831: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8832: /*       oldm=oldms;savm=savms; */
                   8833: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8834: /*       for (h=0; h<=nhstepm; h++){ */
                   8835: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8836: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8837: /*         }  */
                   8838: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8839: /*           kk1=0.;kk2=0; */
                   8840: /*           for(i=1; i<=nlstate;i++) {               */
                   8841: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8842: /*           } */
                   8843: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8844: /*         } */
                   8845: /*       } */
                   8846: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8847: /*     } */
                   8848: /*       } */
                   8849: /*     }  */
                   8850: /*   } */
1.218     brouard  8851:   
1.227     brouard  8852: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8853:   
1.227     brouard  8854: /*   if (popforecast==1) { */
                   8855: /*     free_ivector(popage,0,AGESUP); */
                   8856: /*     free_vector(popeffectif,0,AGESUP); */
                   8857: /*     free_vector(popcount,0,AGESUP); */
                   8858: /*   } */
                   8859: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8860: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8861: /*   fclose(ficrespop); */
                   8862: /* } /\* End of popforecast *\/ */
1.218     brouard  8863:  
1.126     brouard  8864: int fileappend(FILE *fichier, char *optionfich)
                   8865: {
                   8866:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8867:     printf("Problem with file: %s\n", optionfich);
                   8868:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8869:     return (0);
                   8870:   }
                   8871:   fflush(fichier);
                   8872:   return (1);
                   8873: }
                   8874: 
                   8875: 
                   8876: /**************** function prwizard **********************/
                   8877: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8878: {
                   8879: 
                   8880:   /* Wizard to print covariance matrix template */
                   8881: 
1.164     brouard  8882:   char ca[32], cb[32];
                   8883:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8884:   int numlinepar;
                   8885: 
                   8886:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8887:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8888:   for(i=1; i <=nlstate; i++){
                   8889:     jj=0;
                   8890:     for(j=1; j <=nlstate+ndeath; j++){
                   8891:       if(j==i) continue;
                   8892:       jj++;
                   8893:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8894:       printf("%1d%1d",i,j);
                   8895:       fprintf(ficparo,"%1d%1d",i,j);
                   8896:       for(k=1; k<=ncovmodel;k++){
                   8897:        /*        printf(" %lf",param[i][j][k]); */
                   8898:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8899:        printf(" 0.");
                   8900:        fprintf(ficparo," 0.");
                   8901:       }
                   8902:       printf("\n");
                   8903:       fprintf(ficparo,"\n");
                   8904:     }
                   8905:   }
                   8906:   printf("# Scales (for hessian or gradient estimation)\n");
                   8907:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8908:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8909:   for(i=1; i <=nlstate; i++){
                   8910:     jj=0;
                   8911:     for(j=1; j <=nlstate+ndeath; j++){
                   8912:       if(j==i) continue;
                   8913:       jj++;
                   8914:       fprintf(ficparo,"%1d%1d",i,j);
                   8915:       printf("%1d%1d",i,j);
                   8916:       fflush(stdout);
                   8917:       for(k=1; k<=ncovmodel;k++){
                   8918:        /*      printf(" %le",delti3[i][j][k]); */
                   8919:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8920:        printf(" 0.");
                   8921:        fprintf(ficparo," 0.");
                   8922:       }
                   8923:       numlinepar++;
                   8924:       printf("\n");
                   8925:       fprintf(ficparo,"\n");
                   8926:     }
                   8927:   }
                   8928:   printf("# Covariance matrix\n");
                   8929: /* # 121 Var(a12)\n\ */
                   8930: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8931: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   8932: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   8933: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   8934: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   8935: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   8936: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   8937:   fflush(stdout);
                   8938:   fprintf(ficparo,"# Covariance matrix\n");
                   8939:   /* # 121 Var(a12)\n\ */
                   8940:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   8941:   /* #   ...\n\ */
                   8942:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   8943:   
                   8944:   for(itimes=1;itimes<=2;itimes++){
                   8945:     jj=0;
                   8946:     for(i=1; i <=nlstate; i++){
                   8947:       for(j=1; j <=nlstate+ndeath; j++){
                   8948:        if(j==i) continue;
                   8949:        for(k=1; k<=ncovmodel;k++){
                   8950:          jj++;
                   8951:          ca[0]= k+'a'-1;ca[1]='\0';
                   8952:          if(itimes==1){
                   8953:            printf("#%1d%1d%d",i,j,k);
                   8954:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   8955:          }else{
                   8956:            printf("%1d%1d%d",i,j,k);
                   8957:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   8958:            /*  printf(" %.5le",matcov[i][j]); */
                   8959:          }
                   8960:          ll=0;
                   8961:          for(li=1;li <=nlstate; li++){
                   8962:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   8963:              if(lj==li) continue;
                   8964:              for(lk=1;lk<=ncovmodel;lk++){
                   8965:                ll++;
                   8966:                if(ll<=jj){
                   8967:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   8968:                  if(ll<jj){
                   8969:                    if(itimes==1){
                   8970:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8971:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   8972:                    }else{
                   8973:                      printf(" 0.");
                   8974:                      fprintf(ficparo," 0.");
                   8975:                    }
                   8976:                  }else{
                   8977:                    if(itimes==1){
                   8978:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   8979:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   8980:                    }else{
                   8981:                      printf(" 0.");
                   8982:                      fprintf(ficparo," 0.");
                   8983:                    }
                   8984:                  }
                   8985:                }
                   8986:              } /* end lk */
                   8987:            } /* end lj */
                   8988:          } /* end li */
                   8989:          printf("\n");
                   8990:          fprintf(ficparo,"\n");
                   8991:          numlinepar++;
                   8992:        } /* end k*/
                   8993:       } /*end j */
                   8994:     } /* end i */
                   8995:   } /* end itimes */
                   8996: 
                   8997: } /* end of prwizard */
                   8998: /******************* Gompertz Likelihood ******************************/
                   8999: double gompertz(double x[])
                   9000: { 
                   9001:   double A,B,L=0.0,sump=0.,num=0.;
                   9002:   int i,n=0; /* n is the size of the sample */
                   9003: 
1.220     brouard  9004:   for (i=1;i<=imx ; i++) {
1.126     brouard  9005:     sump=sump+weight[i];
                   9006:     /*    sump=sump+1;*/
                   9007:     num=num+1;
                   9008:   }
                   9009:  
                   9010:  
                   9011:   /* for (i=0; i<=imx; i++) 
                   9012:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9013: 
                   9014:   for (i=1;i<=imx ; i++)
                   9015:     {
                   9016:       if (cens[i] == 1 && wav[i]>1)
                   9017:        A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9018:       
                   9019:       if (cens[i] == 0 && wav[i]>1)
                   9020:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                   9021:             +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
                   9022:       
                   9023:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9024:       if (wav[i] > 1 ) { /* ??? */
                   9025:        L=L+A*weight[i];
                   9026:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9027:       }
                   9028:     }
                   9029: 
                   9030:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9031:  
                   9032:   return -2*L*num/sump;
                   9033: }
                   9034: 
1.136     brouard  9035: #ifdef GSL
                   9036: /******************* Gompertz_f Likelihood ******************************/
                   9037: double gompertz_f(const gsl_vector *v, void *params)
                   9038: { 
                   9039:   double A,B,LL=0.0,sump=0.,num=0.;
                   9040:   double *x= (double *) v->data;
                   9041:   int i,n=0; /* n is the size of the sample */
                   9042: 
                   9043:   for (i=0;i<=imx-1 ; i++) {
                   9044:     sump=sump+weight[i];
                   9045:     /*    sump=sump+1;*/
                   9046:     num=num+1;
                   9047:   }
                   9048:  
                   9049:  
                   9050:   /* for (i=0; i<=imx; i++) 
                   9051:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9052:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9053:   for (i=1;i<=imx ; i++)
                   9054:     {
                   9055:       if (cens[i] == 1 && wav[i]>1)
                   9056:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9057:       
                   9058:       if (cens[i] == 0 && wav[i]>1)
                   9059:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9060:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9061:       
                   9062:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9063:       if (wav[i] > 1 ) { /* ??? */
                   9064:        LL=LL+A*weight[i];
                   9065:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9066:       }
                   9067:     }
                   9068: 
                   9069:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9070:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9071:  
                   9072:   return -2*LL*num/sump;
                   9073: }
                   9074: #endif
                   9075: 
1.126     brouard  9076: /******************* Printing html file ***********/
1.201     brouard  9077: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9078:                  int lastpass, int stepm, int weightopt, char model[],\
                   9079:                  int imx,  double p[],double **matcov,double agemortsup){
                   9080:   int i,k;
                   9081: 
                   9082:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9083:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9084:   for (i=1;i<=2;i++) 
                   9085:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9086:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9087:   fprintf(fichtm,"</ul>");
                   9088: 
                   9089: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9090: 
                   9091:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9092: 
                   9093:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9094:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9095: 
                   9096:  
                   9097:   fflush(fichtm);
                   9098: }
                   9099: 
                   9100: /******************* Gnuplot file **************/
1.201     brouard  9101: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9102: 
                   9103:   char dirfileres[132],optfileres[132];
1.164     brouard  9104: 
1.126     brouard  9105:   int ng;
                   9106: 
                   9107: 
                   9108:   /*#ifdef windows */
                   9109:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9110:     /*#endif */
                   9111: 
                   9112: 
                   9113:   strcpy(dirfileres,optionfilefiname);
                   9114:   strcpy(optfileres,"vpl");
1.199     brouard  9115:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9116:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9117:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9118:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9119:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9120: 
                   9121: } 
                   9122: 
1.136     brouard  9123: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9124: {
1.126     brouard  9125: 
1.136     brouard  9126:   /*-------- data file ----------*/
                   9127:   FILE *fic;
                   9128:   char dummy[]="                         ";
1.240     brouard  9129:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9130:   int lstra;
1.136     brouard  9131:   int linei, month, year,iout;
                   9132:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9133:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9134:   char *stratrunc;
1.223     brouard  9135: 
1.240     brouard  9136:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9137:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9138: 
1.240     brouard  9139:   for(v=1; v <=ncovcol;v++){
                   9140:     DummyV[v]=0;
                   9141:     FixedV[v]=0;
                   9142:   }
                   9143:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9144:     DummyV[v]=1;
                   9145:     FixedV[v]=0;
                   9146:   }
                   9147:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9148:     DummyV[v]=0;
                   9149:     FixedV[v]=1;
                   9150:   }
                   9151:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9152:     DummyV[v]=1;
                   9153:     FixedV[v]=1;
                   9154:   }
                   9155:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9156:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9157:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9158:   }
1.126     brouard  9159: 
1.136     brouard  9160:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9161:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9162:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9163:   }
1.126     brouard  9164: 
1.136     brouard  9165:   i=1;
                   9166:   linei=0;
                   9167:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9168:     linei=linei+1;
                   9169:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9170:       if(line[j] == '\t')
                   9171:        line[j] = ' ';
                   9172:     }
                   9173:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9174:       ;
                   9175:     };
                   9176:     line[j+1]=0;  /* Trims blanks at end of line */
                   9177:     if(line[0]=='#'){
                   9178:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9179:       printf("Comment line\n%s\n",line);
                   9180:       continue;
                   9181:     }
                   9182:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9183:     strcpy(line, linetmp);
1.223     brouard  9184:     
                   9185:     /* Loops on waves */
                   9186:     for (j=maxwav;j>=1;j--){
                   9187:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9188:        cutv(stra, strb, line, ' '); 
                   9189:        if(strb[0]=='.') { /* Missing value */
                   9190:          lval=-1;
                   9191:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9192:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9193:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9194:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9195:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9196:            return 1;
                   9197:          }
                   9198:        }else{
                   9199:          errno=0;
                   9200:          /* what_kind_of_number(strb); */
                   9201:          dval=strtod(strb,&endptr); 
                   9202:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9203:          /* if(strb != endptr && *endptr == '\0') */
                   9204:          /*    dval=dlval; */
                   9205:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9206:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9207:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9208:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9209:            return 1;
                   9210:          }
                   9211:          cotqvar[j][iv][i]=dval; 
                   9212:          cotvar[j][ntv+iv][i]=dval; 
                   9213:        }
                   9214:        strcpy(line,stra);
1.223     brouard  9215:       }/* end loop ntqv */
1.225     brouard  9216:       
1.223     brouard  9217:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9218:        cutv(stra, strb, line, ' '); 
                   9219:        if(strb[0]=='.') { /* Missing value */
                   9220:          lval=-1;
                   9221:        }else{
                   9222:          errno=0;
                   9223:          lval=strtol(strb,&endptr,10); 
                   9224:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9225:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9226:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9227:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9228:            return 1;
                   9229:          }
                   9230:        }
                   9231:        if(lval <-1 || lval >1){
                   9232:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9233:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9234:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9235:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9236:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9237:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9238:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9239:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9240:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9241:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9242:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9243:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9244:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9245:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9246:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9247:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9248:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9249:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9250:          return 1;
                   9251:        }
                   9252:        cotvar[j][iv][i]=(double)(lval);
                   9253:        strcpy(line,stra);
1.223     brouard  9254:       }/* end loop ntv */
1.225     brouard  9255:       
1.223     brouard  9256:       /* Statuses  at wave */
1.137     brouard  9257:       cutv(stra, strb, line, ' '); 
1.223     brouard  9258:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9259:        lval=-1;
1.136     brouard  9260:       }else{
1.238     brouard  9261:        errno=0;
                   9262:        lval=strtol(strb,&endptr,10); 
                   9263:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9264:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9265:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9266:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9267:          return 1;
                   9268:        }
1.136     brouard  9269:       }
1.225     brouard  9270:       
1.136     brouard  9271:       s[j][i]=lval;
1.225     brouard  9272:       
1.223     brouard  9273:       /* Date of Interview */
1.136     brouard  9274:       strcpy(line,stra);
                   9275:       cutv(stra, strb,line,' ');
1.169     brouard  9276:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9277:       }
1.169     brouard  9278:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9279:        month=99;
                   9280:        year=9999;
1.136     brouard  9281:       }else{
1.225     brouard  9282:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9283:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9284:        return 1;
1.136     brouard  9285:       }
                   9286:       anint[j][i]= (double) year; 
                   9287:       mint[j][i]= (double)month; 
                   9288:       strcpy(line,stra);
1.223     brouard  9289:     } /* End loop on waves */
1.225     brouard  9290:     
1.223     brouard  9291:     /* Date of death */
1.136     brouard  9292:     cutv(stra, strb,line,' '); 
1.169     brouard  9293:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9294:     }
1.169     brouard  9295:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9296:       month=99;
                   9297:       year=9999;
                   9298:     }else{
1.141     brouard  9299:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9300:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9301:       return 1;
1.136     brouard  9302:     }
                   9303:     andc[i]=(double) year; 
                   9304:     moisdc[i]=(double) month; 
                   9305:     strcpy(line,stra);
                   9306:     
1.223     brouard  9307:     /* Date of birth */
1.136     brouard  9308:     cutv(stra, strb,line,' '); 
1.169     brouard  9309:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9310:     }
1.169     brouard  9311:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9312:       month=99;
                   9313:       year=9999;
                   9314:     }else{
1.141     brouard  9315:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9316:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9317:       return 1;
1.136     brouard  9318:     }
                   9319:     if (year==9999) {
1.141     brouard  9320:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9321:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9322:       return 1;
                   9323:       
1.136     brouard  9324:     }
                   9325:     annais[i]=(double)(year);
                   9326:     moisnais[i]=(double)(month); 
                   9327:     strcpy(line,stra);
1.225     brouard  9328:     
1.223     brouard  9329:     /* Sample weight */
1.136     brouard  9330:     cutv(stra, strb,line,' '); 
                   9331:     errno=0;
                   9332:     dval=strtod(strb,&endptr); 
                   9333:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9334:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9335:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9336:       fflush(ficlog);
                   9337:       return 1;
                   9338:     }
                   9339:     weight[i]=dval; 
                   9340:     strcpy(line,stra);
1.225     brouard  9341:     
1.223     brouard  9342:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9343:       cutv(stra, strb, line, ' '); 
                   9344:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9345:        lval=-1;
1.223     brouard  9346:       }else{
1.225     brouard  9347:        errno=0;
                   9348:        /* what_kind_of_number(strb); */
                   9349:        dval=strtod(strb,&endptr);
                   9350:        /* if(strb != endptr && *endptr == '\0') */
                   9351:        /*   dval=dlval; */
                   9352:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9353:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9354:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9355:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9356:          return 1;
                   9357:        }
                   9358:        coqvar[iv][i]=dval; 
1.226     brouard  9359:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9360:       }
                   9361:       strcpy(line,stra);
                   9362:     }/* end loop nqv */
1.136     brouard  9363:     
1.223     brouard  9364:     /* Covariate values */
1.136     brouard  9365:     for (j=ncovcol;j>=1;j--){
                   9366:       cutv(stra, strb,line,' '); 
1.223     brouard  9367:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9368:        lval=-1;
1.136     brouard  9369:       }else{
1.225     brouard  9370:        errno=0;
                   9371:        lval=strtol(strb,&endptr,10); 
                   9372:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9373:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9374:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9375:          return 1;
                   9376:        }
1.136     brouard  9377:       }
                   9378:       if(lval <-1 || lval >1){
1.225     brouard  9379:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9380:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9381:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9382:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9383:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9384:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9385:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9386:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9387:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9388:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9389:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9390:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9391:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9392:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9393:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9394:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9395:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9396:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9397:        return 1;
1.136     brouard  9398:       }
                   9399:       covar[j][i]=(double)(lval);
                   9400:       strcpy(line,stra);
                   9401:     }  
                   9402:     lstra=strlen(stra);
1.225     brouard  9403:     
1.136     brouard  9404:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9405:       stratrunc = &(stra[lstra-9]);
                   9406:       num[i]=atol(stratrunc);
                   9407:     }
                   9408:     else
                   9409:       num[i]=atol(stra);
                   9410:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9411:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9412:     
                   9413:     i=i+1;
                   9414:   } /* End loop reading  data */
1.225     brouard  9415:   
1.136     brouard  9416:   *imax=i-1; /* Number of individuals */
                   9417:   fclose(fic);
1.225     brouard  9418:   
1.136     brouard  9419:   return (0);
1.164     brouard  9420:   /* endread: */
1.225     brouard  9421:   printf("Exiting readdata: ");
                   9422:   fclose(fic);
                   9423:   return (1);
1.223     brouard  9424: }
1.126     brouard  9425: 
1.234     brouard  9426: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9427:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9428:   while (*p2 == ' ')
1.234     brouard  9429:     p2++; 
                   9430:   /* while ((*p1++ = *p2++) !=0) */
                   9431:   /*   ; */
                   9432:   /* do */
                   9433:   /*   while (*p2 == ' ') */
                   9434:   /*     p2++; */
                   9435:   /* while (*p1++ == *p2++); */
                   9436:   *stri=p2; 
1.145     brouard  9437: }
                   9438: 
1.235     brouard  9439: int decoderesult ( char resultline[], int nres)
1.230     brouard  9440: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9441: {
1.235     brouard  9442:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9443:   char resultsav[MAXLINE];
1.234     brouard  9444:   int resultmodel[MAXLINE];
                   9445:   int modelresult[MAXLINE];
1.230     brouard  9446:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9447: 
1.234     brouard  9448:   removefirstspace(&resultline);
1.233     brouard  9449:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9450: 
                   9451:   if (strstr(resultline,"v") !=0){
                   9452:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9453:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9454:     return 1;
                   9455:   }
                   9456:   trimbb(resultsav, resultline);
                   9457:   if (strlen(resultsav) >1){
                   9458:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9459:   }
1.253     brouard  9460:   if(j == 0){ /* Resultline but no = */
                   9461:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9462:     return (0);
                   9463:   }
                   9464:     
1.234     brouard  9465:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9466:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9467:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9468:   }
                   9469:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9470:     if(nbocc(resultsav,'=') >1){
                   9471:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9472:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9473:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9474:     }else
                   9475:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9476:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9477:     
1.230     brouard  9478:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9479:     Tvarsel[k]=atoi(strc);
                   9480:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9481:     /* cptcovsel++;     */
                   9482:     if (nbocc(stra,'=') >0)
                   9483:       strcpy(resultsav,stra); /* and analyzes it */
                   9484:   }
1.235     brouard  9485:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9486:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9487:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9488:       match=0;
1.236     brouard  9489:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9490:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9491:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9492:          match=1;
                   9493:          break;
                   9494:        }
                   9495:       }
                   9496:       if(match == 0){
                   9497:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9498:       }
                   9499:     }
                   9500:   }
1.235     brouard  9501:   /* Checking for missing or useless values in comparison of current model needs */
                   9502:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9503:     match=0;
1.235     brouard  9504:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9505:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9506:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9507:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9508:          ++match;
                   9509:        }
                   9510:       }
                   9511:     }
                   9512:     if(match == 0){
                   9513:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9514:     }else if(match > 1){
                   9515:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9516:     }
                   9517:   }
1.235     brouard  9518:       
1.234     brouard  9519:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9520:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9521:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9522:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9523:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9524:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9525:   /*    1 0 0 0 */
                   9526:   /*    2 1 0 0 */
                   9527:   /*    3 0 1 0 */ 
                   9528:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9529:   /*    5 0 0 1 */
                   9530:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9531:   /*    7 0 1 1 */
                   9532:   /*    8 1 1 1 */
1.237     brouard  9533:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9534:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9535:   /* V5*age V5 known which value for nres?  */
                   9536:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9537:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9538:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9539:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9540:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9541:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9542:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9543:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9544:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9545:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9546:       k4++;;
                   9547:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9548:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9549:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9550:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9551:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9552:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9553:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9554:       k4q++;;
                   9555:     }
                   9556:   }
1.234     brouard  9557:   
1.235     brouard  9558:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9559:   return (0);
                   9560: }
1.235     brouard  9561: 
1.230     brouard  9562: int decodemodel( char model[], int lastobs)
                   9563:  /**< This routine decodes the model and returns:
1.224     brouard  9564:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9565:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9566:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9567:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9568:        * - cptcovage number of covariates with age*products =2
                   9569:        * - cptcovs number of simple covariates
                   9570:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9571:        *     which is a new column after the 9 (ncovcol) variables. 
                   9572:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9573:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9574:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9575:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9576:        */
1.136     brouard  9577: {
1.238     brouard  9578:   int i, j, k, ks, v;
1.227     brouard  9579:   int  j1, k1, k2, k3, k4;
1.136     brouard  9580:   char modelsav[80];
1.145     brouard  9581:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9582:   char *strpt;
1.136     brouard  9583: 
1.145     brouard  9584:   /*removespace(model);*/
1.136     brouard  9585:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9586:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9587:     if (strstr(model,"AGE") !=0){
1.192     brouard  9588:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9589:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9590:       return 1;
                   9591:     }
1.141     brouard  9592:     if (strstr(model,"v") !=0){
                   9593:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9594:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9595:       return 1;
                   9596:     }
1.187     brouard  9597:     strcpy(modelsav,model); 
                   9598:     if ((strpt=strstr(model,"age*age")) !=0){
                   9599:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9600:       if(strpt != model){
1.234     brouard  9601:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9602:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9603:  corresponding column of parameters.\n",model);
1.234     brouard  9604:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9605:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9606:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9607:        return 1;
1.225     brouard  9608:       }
1.187     brouard  9609:       nagesqr=1;
                   9610:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9611:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9612:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9613:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9614:       else 
1.234     brouard  9615:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9616:     }else
                   9617:       nagesqr=0;
                   9618:     if (strlen(modelsav) >1){
                   9619:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9620:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9621:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9622:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9623:                     * cst, age and age*age 
                   9624:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9625:       /* including age products which are counted in cptcovage.
                   9626:        * but the covariates which are products must be treated 
                   9627:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9628:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9629:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9630:       
                   9631:       
1.187     brouard  9632:       /*   Design
                   9633:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9634:        *  <          ncovcol=8                >
                   9635:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9636:        *   k=  1    2      3       4     5       6      7        8
                   9637:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9638:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9639:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9640:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9641:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9642:        *  Tage[++cptcovage]=k
                   9643:        *       if products, new covar are created after ncovcol with k1
                   9644:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9645:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9646:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9647:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9648:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9649:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9650:        *  <          ncovcol=8                >
                   9651:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9652:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9653:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9654:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9655:        * p Tprod[1]@2={                         6, 5}
                   9656:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9657:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9658:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9659:        *How to reorganize?
                   9660:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9661:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9662:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9663:        * Struct []
                   9664:        */
1.225     brouard  9665:       
1.187     brouard  9666:       /* This loop fills the array Tvar from the string 'model'.*/
                   9667:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9668:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9669:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9670:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9671:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9672:       /*       k=1 Tvar[1]=2 (from V2) */
                   9673:       /*       k=5 Tvar[5] */
                   9674:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9675:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9676:       /*       } */
1.198     brouard  9677:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9678:       /*
                   9679:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9680:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9681:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9682:       }
1.187     brouard  9683:       cptcovage=0;
                   9684:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9685:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9686:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9687:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9688:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9689:        /*scanf("%d",i);*/
                   9690:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9691:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9692:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9693:            /* covar is not filled and then is empty */
                   9694:            cptcovprod--;
                   9695:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9696:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9697:            Typevar[k]=1;  /* 1 for age product */
                   9698:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9699:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9700:            /*printf("stre=%s ", stre);*/
                   9701:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9702:            cptcovprod--;
                   9703:            cutl(stre,strb,strc,'V');
                   9704:            Tvar[k]=atoi(stre);
                   9705:            Typevar[k]=1;  /* 1 for age product */
                   9706:            cptcovage++;
                   9707:            Tage[cptcovage]=k;
                   9708:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9709:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9710:            cptcovn++;
                   9711:            cptcovprodnoage++;k1++;
                   9712:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9713:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9714:                                                because this model-covariate is a construction we invent a new column
                   9715:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9716:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9717:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9718:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9719:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9720:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9721:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9722:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9723:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9724:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9725:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9726:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9727:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9728:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9729:            for (i=1; i<=lastobs;i++){
                   9730:              /* Computes the new covariate which is a product of
                   9731:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9732:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9733:            }
                   9734:          } /* End age is not in the model */
                   9735:        } /* End if model includes a product */
                   9736:        else { /* no more sum */
                   9737:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9738:          /*  scanf("%d",i);*/
                   9739:          cutl(strd,strc,strb,'V');
                   9740:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9741:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9742:          Tvar[k]=atoi(strd);
                   9743:          Typevar[k]=0;  /* 0 for simple covariates */
                   9744:        }
                   9745:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9746:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9747:                                  scanf("%d",i);*/
1.187     brouard  9748:       } /* end of loop + on total covariates */
                   9749:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9750:   } /* end if strlen(model == 0) */
1.136     brouard  9751:   
                   9752:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9753:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9754:   
1.136     brouard  9755:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9756:      printf("cptcovprod=%d ", cptcovprod);
                   9757:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9758:      scanf("%d ",i);*/
                   9759: 
                   9760: 
1.230     brouard  9761: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9762:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9763: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9764:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9765:    k =           1    2   3     4       5       6      7      8        9
                   9766:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9767:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9768:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9769:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9770:          Tmodelind[combination of covar]=k;
1.225     brouard  9771: */  
                   9772: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9773:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9774:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9775:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9776:   printf("Model=%s\n\
                   9777: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9778: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9779: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9780:   fprintf(ficlog,"Model=%s\n\
                   9781: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9782: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9783: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  9784:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9785:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9786:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9787:       Fixed[k]= 0;
                   9788:       Dummy[k]= 0;
1.225     brouard  9789:       ncoveff++;
1.232     brouard  9790:       ncovf++;
1.234     brouard  9791:       nsd++;
                   9792:       modell[k].maintype= FTYPE;
                   9793:       TvarsD[nsd]=Tvar[k];
                   9794:       TvarsDind[nsd]=k;
                   9795:       TvarF[ncovf]=Tvar[k];
                   9796:       TvarFind[ncovf]=k;
                   9797:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9798:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9799:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9800:       Fixed[k]= 0;
                   9801:       Dummy[k]= 0;
                   9802:       ncoveff++;
                   9803:       ncovf++;
                   9804:       modell[k].maintype= FTYPE;
                   9805:       TvarF[ncovf]=Tvar[k];
                   9806:       TvarFind[ncovf]=k;
1.230     brouard  9807:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9808:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9809:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9810:       Fixed[k]= 0;
                   9811:       Dummy[k]= 1;
1.230     brouard  9812:       nqfveff++;
1.234     brouard  9813:       modell[k].maintype= FTYPE;
                   9814:       modell[k].subtype= FQ;
                   9815:       nsq++;
                   9816:       TvarsQ[nsq]=Tvar[k];
                   9817:       TvarsQind[nsq]=k;
1.232     brouard  9818:       ncovf++;
1.234     brouard  9819:       TvarF[ncovf]=Tvar[k];
                   9820:       TvarFind[ncovf]=k;
1.231     brouard  9821:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9822:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9823:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9824:       Fixed[k]= 1;
                   9825:       Dummy[k]= 0;
1.225     brouard  9826:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9827:       modell[k].maintype= VTYPE;
                   9828:       modell[k].subtype= VD;
                   9829:       nsd++;
                   9830:       TvarsD[nsd]=Tvar[k];
                   9831:       TvarsDind[nsd]=k;
                   9832:       ncovv++; /* Only simple time varying variables */
                   9833:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9834:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9835:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9836:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9837:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9838:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9839:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9840:       Fixed[k]= 1;
                   9841:       Dummy[k]= 1;
                   9842:       nqtveff++;
                   9843:       modell[k].maintype= VTYPE;
                   9844:       modell[k].subtype= VQ;
                   9845:       ncovv++; /* Only simple time varying variables */
                   9846:       nsq++;
                   9847:       TvarsQ[nsq]=Tvar[k];
                   9848:       TvarsQind[nsq]=k;
                   9849:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9850:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9851:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9852:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9853:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9854:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9855:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9856:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9857:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9858:       ncova++;
                   9859:       TvarA[ncova]=Tvar[k];
                   9860:       TvarAind[ncova]=k;
1.231     brouard  9861:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9862:        Fixed[k]= 2;
                   9863:        Dummy[k]= 2;
                   9864:        modell[k].maintype= ATYPE;
                   9865:        modell[k].subtype= APFD;
                   9866:        /* ncoveff++; */
1.227     brouard  9867:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  9868:        Fixed[k]= 2;
                   9869:        Dummy[k]= 3;
                   9870:        modell[k].maintype= ATYPE;
                   9871:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   9872:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  9873:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  9874:        Fixed[k]= 3;
                   9875:        Dummy[k]= 2;
                   9876:        modell[k].maintype= ATYPE;
                   9877:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   9878:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  9879:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9880:        Fixed[k]= 3;
                   9881:        Dummy[k]= 3;
                   9882:        modell[k].maintype= ATYPE;
                   9883:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   9884:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  9885:       }
                   9886:     }else if (Typevar[k] == 2) {  /* product without age */
                   9887:       k1=Tposprod[k];
                   9888:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  9889:        if(Tvard[k1][2] <=ncovcol){
                   9890:          Fixed[k]= 1;
                   9891:          Dummy[k]= 0;
                   9892:          modell[k].maintype= FTYPE;
                   9893:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   9894:          ncovf++; /* Fixed variables without age */
                   9895:          TvarF[ncovf]=Tvar[k];
                   9896:          TvarFind[ncovf]=k;
                   9897:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9898:          Fixed[k]= 0;  /* or 2 ?*/
                   9899:          Dummy[k]= 1;
                   9900:          modell[k].maintype= FTYPE;
                   9901:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   9902:          ncovf++; /* Varying variables without age */
                   9903:          TvarF[ncovf]=Tvar[k];
                   9904:          TvarFind[ncovf]=k;
                   9905:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9906:          Fixed[k]= 1;
                   9907:          Dummy[k]= 0;
                   9908:          modell[k].maintype= VTYPE;
                   9909:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   9910:          ncovv++; /* Varying variables without age */
                   9911:          TvarV[ncovv]=Tvar[k];
                   9912:          TvarVind[ncovv]=k;
                   9913:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9914:          Fixed[k]= 1;
                   9915:          Dummy[k]= 1;
                   9916:          modell[k].maintype= VTYPE;
                   9917:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   9918:          ncovv++; /* Varying variables without age */
                   9919:          TvarV[ncovv]=Tvar[k];
                   9920:          TvarVind[ncovv]=k;
                   9921:        }
1.227     brouard  9922:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  9923:        if(Tvard[k1][2] <=ncovcol){
                   9924:          Fixed[k]= 0;  /* or 2 ?*/
                   9925:          Dummy[k]= 1;
                   9926:          modell[k].maintype= FTYPE;
                   9927:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   9928:          ncovf++; /* Fixed variables without age */
                   9929:          TvarF[ncovf]=Tvar[k];
                   9930:          TvarFind[ncovf]=k;
                   9931:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9932:          Fixed[k]= 1;
                   9933:          Dummy[k]= 1;
                   9934:          modell[k].maintype= VTYPE;
                   9935:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   9936:          ncovv++; /* Varying variables without age */
                   9937:          TvarV[ncovv]=Tvar[k];
                   9938:          TvarVind[ncovv]=k;
                   9939:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9940:          Fixed[k]= 1;
                   9941:          Dummy[k]= 1;
                   9942:          modell[k].maintype= VTYPE;
                   9943:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   9944:          ncovv++; /* Varying variables without age */
                   9945:          TvarV[ncovv]=Tvar[k];
                   9946:          TvarVind[ncovv]=k;
                   9947:          ncovv++; /* Varying variables without age */
                   9948:          TvarV[ncovv]=Tvar[k];
                   9949:          TvarVind[ncovv]=k;
                   9950:        }
1.227     brouard  9951:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  9952:        if(Tvard[k1][2] <=ncovcol){
                   9953:          Fixed[k]= 1;
                   9954:          Dummy[k]= 1;
                   9955:          modell[k].maintype= VTYPE;
                   9956:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   9957:          ncovv++; /* Varying variables without age */
                   9958:          TvarV[ncovv]=Tvar[k];
                   9959:          TvarVind[ncovv]=k;
                   9960:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9961:          Fixed[k]= 1;
                   9962:          Dummy[k]= 1;
                   9963:          modell[k].maintype= VTYPE;
                   9964:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   9965:          ncovv++; /* Varying variables without age */
                   9966:          TvarV[ncovv]=Tvar[k];
                   9967:          TvarVind[ncovv]=k;
                   9968:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   9969:          Fixed[k]= 1;
                   9970:          Dummy[k]= 0;
                   9971:          modell[k].maintype= VTYPE;
                   9972:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   9973:          ncovv++; /* Varying variables without age */
                   9974:          TvarV[ncovv]=Tvar[k];
                   9975:          TvarVind[ncovv]=k;
                   9976:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   9977:          Fixed[k]= 1;
                   9978:          Dummy[k]= 1;
                   9979:          modell[k].maintype= VTYPE;
                   9980:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   9981:          ncovv++; /* Varying variables without age */
                   9982:          TvarV[ncovv]=Tvar[k];
                   9983:          TvarVind[ncovv]=k;
                   9984:        }
1.227     brouard  9985:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  9986:        if(Tvard[k1][2] <=ncovcol){
                   9987:          Fixed[k]= 1;
                   9988:          Dummy[k]= 1;
                   9989:          modell[k].maintype= VTYPE;
                   9990:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   9991:          ncovv++; /* Varying variables without age */
                   9992:          TvarV[ncovv]=Tvar[k];
                   9993:          TvarVind[ncovv]=k;
                   9994:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   9995:          Fixed[k]= 1;
                   9996:          Dummy[k]= 1;
                   9997:          modell[k].maintype= VTYPE;
                   9998:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   9999:          ncovv++; /* Varying variables without age */
                   10000:          TvarV[ncovv]=Tvar[k];
                   10001:          TvarVind[ncovv]=k;
                   10002:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10003:          Fixed[k]= 1;
                   10004:          Dummy[k]= 1;
                   10005:          modell[k].maintype= VTYPE;
                   10006:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   10007:          ncovv++; /* Varying variables without age */
                   10008:          TvarV[ncovv]=Tvar[k];
                   10009:          TvarVind[ncovv]=k;
                   10010:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10011:          Fixed[k]= 1;
                   10012:          Dummy[k]= 1;
                   10013:          modell[k].maintype= VTYPE;
                   10014:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10015:          ncovv++; /* Varying variables without age */
                   10016:          TvarV[ncovv]=Tvar[k];
                   10017:          TvarVind[ncovv]=k;
                   10018:        }
1.227     brouard  10019:       }else{
1.240     brouard  10020:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10021:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10022:       } /*end k1*/
1.225     brouard  10023:     }else{
1.226     brouard  10024:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10025:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10026:     }
1.227     brouard  10027:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10028:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10029:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10030:   }
                   10031:   /* Searching for doublons in the model */
                   10032:   for(k1=1; k1<= cptcovt;k1++){
                   10033:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10034:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10035:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10036:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10037:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10038:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10039:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10040:            return(1);
                   10041:          }
                   10042:        }else if (Typevar[k1] ==2){
                   10043:          k3=Tposprod[k1];
                   10044:          k4=Tposprod[k2];
                   10045:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10046:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10047:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10048:            return(1);
                   10049:          }
                   10050:        }
1.227     brouard  10051:       }
                   10052:     }
1.225     brouard  10053:   }
                   10054:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10055:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10056:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10057:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10058:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10059:   /*endread:*/
1.225     brouard  10060:   printf("Exiting decodemodel: ");
                   10061:   return (1);
1.136     brouard  10062: }
                   10063: 
1.169     brouard  10064: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10065: {/* Check ages at death */
1.136     brouard  10066:   int i, m;
1.218     brouard  10067:   int firstone=0;
                   10068:   
1.136     brouard  10069:   for (i=1; i<=imx; i++) {
                   10070:     for(m=2; (m<= maxwav); m++) {
                   10071:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10072:        anint[m][i]=9999;
1.216     brouard  10073:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10074:          s[m][i]=-1;
1.136     brouard  10075:       }
                   10076:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10077:        *nberr = *nberr + 1;
1.218     brouard  10078:        if(firstone == 0){
                   10079:          firstone=1;
1.260     brouard  10080:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10081:        }
1.262     brouard  10082:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10083:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10084:       }
                   10085:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10086:        (*nberr)++;
1.259     brouard  10087:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10088:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10089:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10090:       }
                   10091:     }
                   10092:   }
                   10093: 
                   10094:   for (i=1; i<=imx; i++)  {
                   10095:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10096:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10097:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10098:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10099:          if(agedc[i]>0){
                   10100:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10101:              agev[m][i]=agedc[i];
1.214     brouard  10102:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10103:            }else {
1.136     brouard  10104:              if ((int)andc[i]!=9999){
                   10105:                nbwarn++;
                   10106:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10107:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10108:                agev[m][i]=-1;
                   10109:              }
                   10110:            }
1.169     brouard  10111:          } /* agedc > 0 */
1.214     brouard  10112:        } /* end if */
1.136     brouard  10113:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10114:                                 years but with the precision of a month */
                   10115:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10116:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10117:            agev[m][i]=1;
                   10118:          else if(agev[m][i] < *agemin){ 
                   10119:            *agemin=agev[m][i];
                   10120:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10121:          }
                   10122:          else if(agev[m][i] >*agemax){
                   10123:            *agemax=agev[m][i];
1.156     brouard  10124:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10125:          }
                   10126:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10127:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10128:        } /* en if 9*/
1.136     brouard  10129:        else { /* =9 */
1.214     brouard  10130:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10131:          agev[m][i]=1;
                   10132:          s[m][i]=-1;
                   10133:        }
                   10134:       }
1.214     brouard  10135:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10136:        agev[m][i]=1;
1.214     brouard  10137:       else{
                   10138:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10139:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10140:        agev[m][i]=0;
                   10141:       }
                   10142:     } /* End for lastpass */
                   10143:   }
1.136     brouard  10144:     
                   10145:   for (i=1; i<=imx; i++)  {
                   10146:     for(m=firstpass; (m<=lastpass); m++){
                   10147:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10148:        (*nberr)++;
1.136     brouard  10149:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10150:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10151:        return 1;
                   10152:       }
                   10153:     }
                   10154:   }
                   10155: 
                   10156:   /*for (i=1; i<=imx; i++){
                   10157:   for (m=firstpass; (m<lastpass); m++){
                   10158:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10159: }
                   10160: 
                   10161: }*/
                   10162: 
                   10163: 
1.139     brouard  10164:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10165:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10166: 
                   10167:   return (0);
1.164     brouard  10168:  /* endread:*/
1.136     brouard  10169:     printf("Exiting calandcheckages: ");
                   10170:     return (1);
                   10171: }
                   10172: 
1.172     brouard  10173: #if defined(_MSC_VER)
                   10174: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10175: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10176: //#include "stdafx.h"
                   10177: //#include <stdio.h>
                   10178: //#include <tchar.h>
                   10179: //#include <windows.h>
                   10180: //#include <iostream>
                   10181: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10182: 
                   10183: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10184: 
                   10185: BOOL IsWow64()
                   10186: {
                   10187:        BOOL bIsWow64 = FALSE;
                   10188: 
                   10189:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10190:        //  (HANDLE, PBOOL);
                   10191: 
                   10192:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10193: 
                   10194:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10195:        const char funcName[] = "IsWow64Process";
                   10196:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10197:                GetProcAddress(module, funcName);
                   10198: 
                   10199:        if (NULL != fnIsWow64Process)
                   10200:        {
                   10201:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10202:                        &bIsWow64))
                   10203:                        //throw std::exception("Unknown error");
                   10204:                        printf("Unknown error\n");
                   10205:        }
                   10206:        return bIsWow64 != FALSE;
                   10207: }
                   10208: #endif
1.177     brouard  10209: 
1.191     brouard  10210: void syscompilerinfo(int logged)
1.292     brouard  10211: {
                   10212: #include <stdint.h>
                   10213: 
                   10214:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10215:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10216:    /* /GS /W3 /Gy
                   10217:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10218:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10219:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10220:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10221:    */ 
                   10222:    /* 64 bits */
1.185     brouard  10223:    /*
                   10224:      /GS /W3 /Gy
                   10225:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10226:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10227:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10228:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10229:    /* Optimization are useless and O3 is slower than O2 */
                   10230:    /*
                   10231:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10232:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10233:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10234:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10235:    */
1.186     brouard  10236:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10237:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10238:       /PDB:"visual studio
                   10239:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10240:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10241:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10242:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10243:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10244:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10245:       uiAccess='false'"
                   10246:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10247:       /NOLOGO /TLBID:1
                   10248:    */
1.292     brouard  10249: 
                   10250: 
1.177     brouard  10251: #if defined __INTEL_COMPILER
1.178     brouard  10252: #if defined(__GNUC__)
                   10253:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10254: #endif
1.177     brouard  10255: #elif defined(__GNUC__) 
1.179     brouard  10256: #ifndef  __APPLE__
1.174     brouard  10257: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10258: #endif
1.177     brouard  10259:    struct utsname sysInfo;
1.178     brouard  10260:    int cross = CROSS;
                   10261:    if (cross){
                   10262:           printf("Cross-");
1.191     brouard  10263:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10264:    }
1.174     brouard  10265: #endif
                   10266: 
1.191     brouard  10267:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10268: #if defined(__clang__)
1.191     brouard  10269:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10270: #endif
                   10271: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10272:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10273: #endif
                   10274: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10275:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10276: #endif
                   10277: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10278:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10279: #endif
                   10280: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10281:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10282: #endif
                   10283: #if defined(_MSC_VER)
1.191     brouard  10284:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10285: #endif
                   10286: #if defined(__PGI)
1.191     brouard  10287:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10288: #endif
                   10289: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10290:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10291: #endif
1.191     brouard  10292:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10293:    
1.167     brouard  10294: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10295: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10296:     // Windows (x64 and x86)
1.191     brouard  10297:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10298: #elif __unix__ // all unices, not all compilers
                   10299:     // Unix
1.191     brouard  10300:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10301: #elif __linux__
                   10302:     // linux
1.191     brouard  10303:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10304: #elif __APPLE__
1.174     brouard  10305:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10306:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10307: #endif
                   10308: 
                   10309: /*  __MINGW32__          */
                   10310: /*  __CYGWIN__  */
                   10311: /* __MINGW64__  */
                   10312: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10313: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10314: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10315: /* _WIN64  // Defined for applications for Win64. */
                   10316: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10317: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10318: 
1.167     brouard  10319: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10320:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10321: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10322:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10323: #else
1.191     brouard  10324:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10325: #endif
                   10326: 
1.169     brouard  10327: #if defined(__GNUC__)
                   10328: # if defined(__GNUC_PATCHLEVEL__)
                   10329: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10330:                             + __GNUC_MINOR__ * 100 \
                   10331:                             + __GNUC_PATCHLEVEL__)
                   10332: # else
                   10333: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10334:                             + __GNUC_MINOR__ * 100)
                   10335: # endif
1.174     brouard  10336:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10337:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10338: 
                   10339:    if (uname(&sysInfo) != -1) {
                   10340:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10341:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10342:    }
                   10343:    else
                   10344:       perror("uname() error");
1.179     brouard  10345:    //#ifndef __INTEL_COMPILER 
                   10346: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10347:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10348:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10349: #endif
1.169     brouard  10350: #endif
1.172     brouard  10351: 
1.286     brouard  10352:    //   void main ()
1.172     brouard  10353:    //   {
1.169     brouard  10354: #if defined(_MSC_VER)
1.174     brouard  10355:    if (IsWow64()){
1.191     brouard  10356:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10357:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10358:    }
                   10359:    else{
1.191     brouard  10360:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10361:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10362:    }
1.172     brouard  10363:    //     printf("\nPress Enter to continue...");
                   10364:    //     getchar();
                   10365:    //   }
                   10366: 
1.169     brouard  10367: #endif
                   10368:    
1.167     brouard  10369: 
1.219     brouard  10370: }
1.136     brouard  10371: 
1.219     brouard  10372: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10373:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10374:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10375:   /* double ftolpl = 1.e-10; */
1.180     brouard  10376:   double age, agebase, agelim;
1.203     brouard  10377:   double tot;
1.180     brouard  10378: 
1.202     brouard  10379:   strcpy(filerespl,"PL_");
                   10380:   strcat(filerespl,fileresu);
                   10381:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10382:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10383:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10384:   }
1.288     brouard  10385:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10386:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10387:   pstamp(ficrespl);
1.288     brouard  10388:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10389:   fprintf(ficrespl,"#Age ");
                   10390:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10391:   fprintf(ficrespl,"\n");
1.180     brouard  10392:   
1.219     brouard  10393:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10394: 
1.219     brouard  10395:   agebase=ageminpar;
                   10396:   agelim=agemaxpar;
1.180     brouard  10397: 
1.227     brouard  10398:   /* i1=pow(2,ncoveff); */
1.234     brouard  10399:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10400:   if (cptcovn < 1){i1=1;}
1.180     brouard  10401: 
1.238     brouard  10402:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10403:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10404:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10405:        continue;
1.235     brouard  10406: 
1.238     brouard  10407:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10408:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10409:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10410:       /* k=k+1; */
                   10411:       /* to clean */
                   10412:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10413:       fprintf(ficrespl,"#******");
                   10414:       printf("#******");
                   10415:       fprintf(ficlog,"#******");
                   10416:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10417:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10418:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10419:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10420:       }
                   10421:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10422:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10423:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10424:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10425:       }
                   10426:       fprintf(ficrespl,"******\n");
                   10427:       printf("******\n");
                   10428:       fprintf(ficlog,"******\n");
                   10429:       if(invalidvarcomb[k]){
                   10430:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10431:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10432:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10433:        continue;
                   10434:       }
1.219     brouard  10435: 
1.238     brouard  10436:       fprintf(ficrespl,"#Age ");
                   10437:       for(j=1;j<=cptcoveff;j++) {
                   10438:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10439:       }
                   10440:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10441:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10442:     
1.238     brouard  10443:       for (age=agebase; age<=agelim; age++){
                   10444:        /* for (age=agebase; age<=agebase; age++){ */
                   10445:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10446:        fprintf(ficrespl,"%.0f ",age );
                   10447:        for(j=1;j<=cptcoveff;j++)
                   10448:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10449:        tot=0.;
                   10450:        for(i=1; i<=nlstate;i++){
                   10451:          tot +=  prlim[i][i];
                   10452:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10453:        }
                   10454:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10455:       } /* Age */
                   10456:       /* was end of cptcod */
                   10457:     } /* cptcov */
                   10458:   } /* nres */
1.219     brouard  10459:   return 0;
1.180     brouard  10460: }
                   10461: 
1.218     brouard  10462: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10463:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10464:        
                   10465:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10466:    * at any age between ageminpar and agemaxpar
                   10467:         */
1.235     brouard  10468:   int i, j, k, i1, nres=0 ;
1.217     brouard  10469:   /* double ftolpl = 1.e-10; */
                   10470:   double age, agebase, agelim;
                   10471:   double tot;
1.218     brouard  10472:   /* double ***mobaverage; */
                   10473:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10474: 
                   10475:   strcpy(fileresplb,"PLB_");
                   10476:   strcat(fileresplb,fileresu);
                   10477:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10478:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10479:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10480:   }
1.288     brouard  10481:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10482:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10483:   pstamp(ficresplb);
1.288     brouard  10484:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10485:   fprintf(ficresplb,"#Age ");
                   10486:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10487:   fprintf(ficresplb,"\n");
                   10488:   
1.218     brouard  10489:   
                   10490:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10491:   
                   10492:   agebase=ageminpar;
                   10493:   agelim=agemaxpar;
                   10494:   
                   10495:   
1.227     brouard  10496:   i1=pow(2,cptcoveff);
1.218     brouard  10497:   if (cptcovn < 1){i1=1;}
1.227     brouard  10498:   
1.238     brouard  10499:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10500:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10501:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10502:        continue;
                   10503:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10504:       fprintf(ficresplb,"#******");
                   10505:       printf("#******");
                   10506:       fprintf(ficlog,"#******");
                   10507:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10508:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10509:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10510:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10511:       }
                   10512:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10513:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10514:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10515:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10516:       }
                   10517:       fprintf(ficresplb,"******\n");
                   10518:       printf("******\n");
                   10519:       fprintf(ficlog,"******\n");
                   10520:       if(invalidvarcomb[k]){
                   10521:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10522:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10523:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10524:        continue;
                   10525:       }
1.218     brouard  10526:     
1.238     brouard  10527:       fprintf(ficresplb,"#Age ");
                   10528:       for(j=1;j<=cptcoveff;j++) {
                   10529:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10530:       }
                   10531:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10532:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10533:     
                   10534:     
1.238     brouard  10535:       for (age=agebase; age<=agelim; age++){
                   10536:        /* for (age=agebase; age<=agebase; age++){ */
                   10537:        if(mobilavproj > 0){
                   10538:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10539:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10540:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10541:        }else if (mobilavproj == 0){
                   10542:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10543:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10544:          exit(1);
                   10545:        }else{
                   10546:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10547:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10548:          /* printf("TOTOT\n"); */
                   10549:           /* exit(1); */
1.238     brouard  10550:        }
                   10551:        fprintf(ficresplb,"%.0f ",age );
                   10552:        for(j=1;j<=cptcoveff;j++)
                   10553:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10554:        tot=0.;
                   10555:        for(i=1; i<=nlstate;i++){
                   10556:          tot +=  bprlim[i][i];
                   10557:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10558:        }
                   10559:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10560:       } /* Age */
                   10561:       /* was end of cptcod */
1.255     brouard  10562:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10563:     } /* end of any combination */
                   10564:   } /* end of nres */  
1.218     brouard  10565:   /* hBijx(p, bage, fage); */
                   10566:   /* fclose(ficrespijb); */
                   10567:   
                   10568:   return 0;
1.217     brouard  10569: }
1.218     brouard  10570:  
1.180     brouard  10571: int hPijx(double *p, int bage, int fage){
                   10572:     /*------------- h Pij x at various ages ------------*/
                   10573: 
                   10574:   int stepsize;
                   10575:   int agelim;
                   10576:   int hstepm;
                   10577:   int nhstepm;
1.235     brouard  10578:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10579: 
                   10580:   double agedeb;
                   10581:   double ***p3mat;
                   10582: 
1.201     brouard  10583:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10584:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10585:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10586:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10587:     }
                   10588:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10589:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10590:   
                   10591:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10592:     /*if (stepm<=24) stepsize=2;*/
                   10593: 
                   10594:     agelim=AGESUP;
                   10595:     hstepm=stepsize*YEARM; /* Every year of age */
                   10596:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10597:                
1.180     brouard  10598:     /* hstepm=1;   aff par mois*/
                   10599:     pstamp(ficrespij);
                   10600:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10601:     i1= pow(2,cptcoveff);
1.218     brouard  10602:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10603:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10604:                /*      k=k+1;  */
1.235     brouard  10605:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10606:     for(k=1; k<=i1;k++){
1.253     brouard  10607:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10608:        continue;
1.183     brouard  10609:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10610:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10611:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10612:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10613:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10614:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10615:       }
1.183     brouard  10616:       fprintf(ficrespij,"******\n");
                   10617:       
                   10618:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10619:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10620:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10621:        
                   10622:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10623:        
1.183     brouard  10624:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10625:        oldm=oldms;savm=savms;
1.235     brouard  10626:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10627:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10628:        for(i=1; i<=nlstate;i++)
                   10629:          for(j=1; j<=nlstate+ndeath;j++)
                   10630:            fprintf(ficrespij," %1d-%1d",i,j);
                   10631:        fprintf(ficrespij,"\n");
                   10632:        for (h=0; h<=nhstepm; h++){
                   10633:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10634:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10635:          for(i=1; i<=nlstate;i++)
                   10636:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10637:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10638:          fprintf(ficrespij,"\n");
                   10639:        }
1.183     brouard  10640:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10641:        fprintf(ficrespij,"\n");
                   10642:       }
1.180     brouard  10643:       /*}*/
                   10644:     }
1.218     brouard  10645:     return 0;
1.180     brouard  10646: }
1.218     brouard  10647:  
                   10648:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10649:     /*------------- h Bij x at various ages ------------*/
                   10650: 
                   10651:   int stepsize;
1.218     brouard  10652:   /* int agelim; */
                   10653:        int ageminl;
1.217     brouard  10654:   int hstepm;
                   10655:   int nhstepm;
1.238     brouard  10656:   int h, i, i1, j, k, nres;
1.218     brouard  10657:        
1.217     brouard  10658:   double agedeb;
                   10659:   double ***p3mat;
1.218     brouard  10660:        
                   10661:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10662:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10663:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10664:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10665:   }
                   10666:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10667:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10668:   
                   10669:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10670:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10671:   
1.218     brouard  10672:   /* agelim=AGESUP; */
1.289     brouard  10673:   ageminl=AGEINF; /* was 30 */
1.218     brouard  10674:   hstepm=stepsize*YEARM; /* Every year of age */
                   10675:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10676:   
                   10677:   /* hstepm=1;   aff par mois*/
                   10678:   pstamp(ficrespijb);
1.255     brouard  10679:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10680:   i1= pow(2,cptcoveff);
1.218     brouard  10681:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10682:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10683:   /*   k=k+1;  */
1.238     brouard  10684:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10685:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10686:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10687:        continue;
                   10688:       fprintf(ficrespijb,"\n#****** ");
                   10689:       for(j=1;j<=cptcoveff;j++)
                   10690:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10691:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10692:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10693:       }
                   10694:       fprintf(ficrespijb,"******\n");
1.264     brouard  10695:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10696:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10697:        continue;
                   10698:       }
                   10699:       
                   10700:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10701:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10702:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
                   10703:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */
                   10704:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 */
                   10705:        
                   10706:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10707:        
1.266     brouard  10708:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10709:        /* and memory limitations if stepm is small */
                   10710: 
1.238     brouard  10711:        /* oldm=oldms;savm=savms; */
                   10712:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10713:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10714:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10715:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10716:        for(i=1; i<=nlstate;i++)
                   10717:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10718:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10719:        fprintf(ficrespijb,"\n");
1.238     brouard  10720:        for (h=0; h<=nhstepm; h++){
                   10721:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10722:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10723:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10724:          for(i=1; i<=nlstate;i++)
                   10725:            for(j=1; j<=nlstate+ndeath;j++)
                   10726:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10727:          fprintf(ficrespijb,"\n");
                   10728:        }
                   10729:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10730:        fprintf(ficrespijb,"\n");
                   10731:       } /* end age deb */
                   10732:     } /* end combination */
                   10733:   } /* end nres */
1.218     brouard  10734:   return 0;
                   10735:  } /*  hBijx */
1.217     brouard  10736: 
1.180     brouard  10737: 
1.136     brouard  10738: /***********************************************/
                   10739: /**************** Main Program *****************/
                   10740: /***********************************************/
                   10741: 
                   10742: int main(int argc, char *argv[])
                   10743: {
                   10744: #ifdef GSL
                   10745:   const gsl_multimin_fminimizer_type *T;
                   10746:   size_t iteri = 0, it;
                   10747:   int rval = GSL_CONTINUE;
                   10748:   int status = GSL_SUCCESS;
                   10749:   double ssval;
                   10750: #endif
                   10751:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  10752:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   10753:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  10754:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10755:   int jj, ll, li, lj, lk;
1.136     brouard  10756:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10757:   int num_filled;
1.136     brouard  10758:   int itimes;
                   10759:   int NDIM=2;
                   10760:   int vpopbased=0;
1.235     brouard  10761:   int nres=0;
1.258     brouard  10762:   int endishere=0;
1.277     brouard  10763:   int noffset=0;
1.274     brouard  10764:   int ncurrv=0; /* Temporary variable */
                   10765:   
1.164     brouard  10766:   char ca[32], cb[32];
1.136     brouard  10767:   /*  FILE *fichtm; *//* Html File */
                   10768:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10769:   struct stat info;
1.191     brouard  10770:   double agedeb=0.;
1.194     brouard  10771: 
                   10772:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10773:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10774: 
1.165     brouard  10775:   double fret;
1.191     brouard  10776:   double dum=0.; /* Dummy variable */
1.136     brouard  10777:   double ***p3mat;
1.218     brouard  10778:   /* double ***mobaverage; */
1.164     brouard  10779: 
                   10780:   char line[MAXLINE];
1.197     brouard  10781:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10782: 
1.234     brouard  10783:   char  modeltemp[MAXLINE];
1.230     brouard  10784:   char resultline[MAXLINE];
                   10785:   
1.136     brouard  10786:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10787:   char *tok, *val; /* pathtot */
1.290     brouard  10788:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  10789:   int c,  h , cpt, c2;
1.191     brouard  10790:   int jl=0;
                   10791:   int i1, j1, jk, stepsize=0;
1.194     brouard  10792:   int count=0;
                   10793: 
1.164     brouard  10794:   int *tab; 
1.136     brouard  10795:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.293     brouard  10796:   int backcast=0; /* defined as global for mlikeli and mle*/
1.136     brouard  10797:   int mobilav=0,popforecast=0;
1.191     brouard  10798:   int hstepm=0, nhstepm=0;
1.136     brouard  10799:   int agemortsup;
                   10800:   float  sumlpop=0.;
                   10801:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10802:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10803: 
1.191     brouard  10804:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10805:   double ftolpl=FTOL;
                   10806:   double **prlim;
1.217     brouard  10807:   double **bprlim;
1.136     brouard  10808:   double ***param; /* Matrix of parameters */
1.251     brouard  10809:   double ***paramstart; /* Matrix of starting parameter values */
                   10810:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10811:   double **matcov; /* Matrix of covariance */
1.203     brouard  10812:   double **hess; /* Hessian matrix */
1.136     brouard  10813:   double ***delti3; /* Scale */
                   10814:   double *delti; /* Scale */
                   10815:   double ***eij, ***vareij;
                   10816:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10817: 
1.136     brouard  10818:   double *epj, vepp;
1.164     brouard  10819: 
1.273     brouard  10820:   double dateprev1, dateprev2;
                   10821:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0;
                   10822:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0;
1.217     brouard  10823: 
1.136     brouard  10824:   double **ximort;
1.145     brouard  10825:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10826:   int *dcwave;
                   10827: 
1.164     brouard  10828:   char z[1]="c";
1.136     brouard  10829: 
                   10830:   /*char  *strt;*/
                   10831:   char strtend[80];
1.126     brouard  10832: 
1.164     brouard  10833: 
1.126     brouard  10834: /*   setlocale (LC_ALL, ""); */
                   10835: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10836: /*   textdomain (PACKAGE); */
                   10837: /*   setlocale (LC_CTYPE, ""); */
                   10838: /*   setlocale (LC_MESSAGES, ""); */
                   10839: 
                   10840:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10841:   rstart_time = time(NULL);  
                   10842:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10843:   start_time = *localtime(&rstart_time);
1.126     brouard  10844:   curr_time=start_time;
1.157     brouard  10845:   /*tml = *localtime(&start_time.tm_sec);*/
                   10846:   /* strcpy(strstart,asctime(&tml)); */
                   10847:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10848: 
                   10849: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10850: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10851: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10852: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10853: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10854: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10855: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10856: /*   strt=asctime(&tmg); */
                   10857: /*   printf("Time(after) =%s",strstart);  */
                   10858: /*  (void) time (&time_value);
                   10859: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   10860: *  tm = *localtime(&time_value);
                   10861: *  strstart=asctime(&tm);
                   10862: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   10863: */
                   10864: 
                   10865:   nberr=0; /* Number of errors and warnings */
                   10866:   nbwarn=0;
1.184     brouard  10867: #ifdef WIN32
                   10868:   _getcwd(pathcd, size);
                   10869: #else
1.126     brouard  10870:   getcwd(pathcd, size);
1.184     brouard  10871: #endif
1.191     brouard  10872:   syscompilerinfo(0);
1.196     brouard  10873:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  10874:   if(argc <=1){
                   10875:     printf("\nEnter the parameter file name: ");
1.205     brouard  10876:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   10877:       printf("ERROR Empty parameter file name\n");
                   10878:       goto end;
                   10879:     }
1.126     brouard  10880:     i=strlen(pathr);
                   10881:     if(pathr[i-1]=='\n')
                   10882:       pathr[i-1]='\0';
1.156     brouard  10883:     i=strlen(pathr);
1.205     brouard  10884:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  10885:       pathr[i-1]='\0';
1.205     brouard  10886:     }
                   10887:     i=strlen(pathr);
                   10888:     if( i==0 ){
                   10889:       printf("ERROR Empty parameter file name\n");
                   10890:       goto end;
                   10891:     }
                   10892:     for (tok = pathr; tok != NULL; ){
1.126     brouard  10893:       printf("Pathr |%s|\n",pathr);
                   10894:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   10895:       printf("val= |%s| pathr=%s\n",val,pathr);
                   10896:       strcpy (pathtot, val);
                   10897:       if(pathr[0] == '\0') break; /* Dirty */
                   10898:     }
                   10899:   }
1.281     brouard  10900:   else if (argc<=2){
                   10901:     strcpy(pathtot,argv[1]);
                   10902:   }
1.126     brouard  10903:   else{
                   10904:     strcpy(pathtot,argv[1]);
1.281     brouard  10905:     strcpy(z,argv[2]);
                   10906:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  10907:   }
                   10908:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   10909:   /*cygwin_split_path(pathtot,path,optionfile);
                   10910:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   10911:   /* cutv(path,optionfile,pathtot,'\\');*/
                   10912: 
                   10913:   /* Split argv[0], imach program to get pathimach */
                   10914:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   10915:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10916:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   10917:  /*   strcpy(pathimach,argv[0]); */
                   10918:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   10919:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   10920:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  10921: #ifdef WIN32
                   10922:   _chdir(path); /* Can be a relative path */
                   10923:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   10924: #else
1.126     brouard  10925:   chdir(path); /* Can be a relative path */
1.184     brouard  10926:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   10927: #endif
                   10928:   printf("Current directory %s!\n",pathcd);
1.126     brouard  10929:   strcpy(command,"mkdir ");
                   10930:   strcat(command,optionfilefiname);
                   10931:   if((outcmd=system(command)) != 0){
1.169     brouard  10932:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  10933:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   10934:     /* fclose(ficlog); */
                   10935: /*     exit(1); */
                   10936:   }
                   10937: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   10938: /*     perror("mkdir"); */
                   10939: /*   } */
                   10940: 
                   10941:   /*-------- arguments in the command line --------*/
                   10942: 
1.186     brouard  10943:   /* Main Log file */
1.126     brouard  10944:   strcat(filelog, optionfilefiname);
                   10945:   strcat(filelog,".log");    /* */
                   10946:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   10947:     printf("Problem with logfile %s\n",filelog);
                   10948:     goto end;
                   10949:   }
                   10950:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  10951:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  10952:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   10953:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   10954:  path=%s \n\
                   10955:  optionfile=%s\n\
                   10956:  optionfilext=%s\n\
1.156     brouard  10957:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  10958: 
1.197     brouard  10959:   syscompilerinfo(1);
1.167     brouard  10960: 
1.126     brouard  10961:   printf("Local time (at start):%s",strstart);
                   10962:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   10963:   fflush(ficlog);
                   10964: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  10965: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  10966: 
                   10967:   /* */
                   10968:   strcpy(fileres,"r");
                   10969:   strcat(fileres, optionfilefiname);
1.201     brouard  10970:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  10971:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  10972:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  10973: 
1.186     brouard  10974:   /* Main ---------arguments file --------*/
1.126     brouard  10975: 
                   10976:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  10977:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   10978:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  10979:     fflush(ficlog);
1.149     brouard  10980:     /* goto end; */
                   10981:     exit(70); 
1.126     brouard  10982:   }
                   10983: 
                   10984:   strcpy(filereso,"o");
1.201     brouard  10985:   strcat(filereso,fileresu);
1.126     brouard  10986:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   10987:     printf("Problem with Output resultfile: %s\n", filereso);
                   10988:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   10989:     fflush(ficlog);
                   10990:     goto end;
                   10991:   }
1.278     brouard  10992:       /*-------- Rewriting parameter file ----------*/
                   10993:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   10994:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   10995:   strcat(rfileres,".");    /* */
                   10996:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   10997:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   10998:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   10999:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   11000:     fflush(ficlog);
                   11001:     goto end;
                   11002:   }
                   11003:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  11004: 
1.278     brouard  11005:                                      
1.126     brouard  11006:   /* Reads comments: lines beginning with '#' */
                   11007:   numlinepar=0;
1.277     brouard  11008:   /* Is it a BOM UTF-8 Windows file? */
                   11009:   /* First parameter line */
1.197     brouard  11010:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11011:     noffset=0;
                   11012:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11013:     {
                   11014:       noffset=noffset+3;
                   11015:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11016:     }
                   11017:     else if( line[0] == (char)0xFE && line[1] == (char)0xFF)
                   11018:     {
                   11019:       noffset=noffset+2;
                   11020:       printf("# File is an UTF16BE BOM file\n");
                   11021:     }
                   11022:     else if( line[0] == 0 && line[1] == 0)
                   11023:     {
                   11024:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11025:        noffset=noffset+4;
                   11026:        printf("# File is an UTF16BE BOM file\n");
                   11027:       }
                   11028:     } else{
                   11029:       ;/*printf(" Not a BOM file\n");*/
                   11030:     }
                   11031:   
1.197     brouard  11032:     /* If line starts with a # it is a comment */
1.277     brouard  11033:     if (line[noffset] == '#') {
1.197     brouard  11034:       numlinepar++;
                   11035:       fputs(line,stdout);
                   11036:       fputs(line,ficparo);
1.278     brouard  11037:       fputs(line,ficres);
1.197     brouard  11038:       fputs(line,ficlog);
                   11039:       continue;
                   11040:     }else
                   11041:       break;
                   11042:   }
                   11043:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11044:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11045:     if (num_filled != 5) {
                   11046:       printf("Should be 5 parameters\n");
1.283     brouard  11047:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11048:     }
1.126     brouard  11049:     numlinepar++;
1.197     brouard  11050:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11051:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11052:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11053:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11054:   }
                   11055:   /* Second parameter line */
                   11056:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11057:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11058:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11059:     if (line[0] == '#') {
                   11060:       numlinepar++;
1.283     brouard  11061:       printf("%s",line);
                   11062:       fprintf(ficres,"%s",line);
                   11063:       fprintf(ficparo,"%s",line);
                   11064:       fprintf(ficlog,"%s",line);
1.197     brouard  11065:       continue;
                   11066:     }else
                   11067:       break;
                   11068:   }
1.223     brouard  11069:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11070:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11071:     if (num_filled != 11) {
                   11072:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11073:       printf("but line=%s\n",line);
1.283     brouard  11074:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11075:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11076:     }
1.286     brouard  11077:     if( lastpass > maxwav){
                   11078:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11079:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11080:       fflush(ficlog);
                   11081:       goto end;
                   11082:     }
                   11083:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11084:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11085:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11086:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11087:   }
1.203     brouard  11088:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11089:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11090:   /* Third parameter line */
                   11091:   while(fgets(line, MAXLINE, ficpar)) {
                   11092:     /* If line starts with a # it is a comment */
                   11093:     if (line[0] == '#') {
                   11094:       numlinepar++;
1.283     brouard  11095:       printf("%s",line);
                   11096:       fprintf(ficres,"%s",line);
                   11097:       fprintf(ficparo,"%s",line);
                   11098:       fprintf(ficlog,"%s",line);
1.197     brouard  11099:       continue;
                   11100:     }else
                   11101:       break;
                   11102:   }
1.201     brouard  11103:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11104:     if (num_filled != 1){
                   11105:       printf("ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
                   11106:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age' %s\n",num_filled, line);
1.197     brouard  11107:       model[0]='\0';
                   11108:       goto end;
                   11109:     }
                   11110:     else{
                   11111:       if (model[0]=='+'){
                   11112:        for(i=1; i<=strlen(model);i++)
                   11113:          modeltemp[i-1]=model[i];
1.201     brouard  11114:        strcpy(model,modeltemp); 
1.197     brouard  11115:       }
                   11116:     }
1.199     brouard  11117:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11118:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11119:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11120:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11121:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11122:   }
                   11123:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11124:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11125:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11126:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11127:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11128:   fflush(ficlog);
1.190     brouard  11129:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11130:   if(model[0]=='#'){
1.279     brouard  11131:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11132:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11133:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11134:     if(mle != -1){
1.279     brouard  11135:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11136:       exit(1);
                   11137:     }
                   11138:   }
1.126     brouard  11139:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11140:     ungetc(c,ficpar);
                   11141:     fgets(line, MAXLINE, ficpar);
                   11142:     numlinepar++;
1.195     brouard  11143:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11144:       z[0]=line[1];
                   11145:     }
                   11146:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11147:     fputs(line, stdout);
                   11148:     //puts(line);
1.126     brouard  11149:     fputs(line,ficparo);
                   11150:     fputs(line,ficlog);
                   11151:   }
                   11152:   ungetc(c,ficpar);
                   11153: 
                   11154:    
1.290     brouard  11155:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11156:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11157:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11158:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11159:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11160:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11161:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11162:   */
                   11163:   if (strlen(model)>1) 
1.187     brouard  11164:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11165:   else
1.187     brouard  11166:     ncovmodel=2; /* Constant and age */
1.133     brouard  11167:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11168:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11169:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11170:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11171:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11172:     fflush(stdout);
                   11173:     fclose (ficlog);
                   11174:     goto end;
                   11175:   }
1.126     brouard  11176:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11177:   delti=delti3[1][1];
                   11178:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11179:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11180: /* We could also provide initial parameters values giving by simple logistic regression 
                   11181:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11182:       /* for(i=1;i<nlstate;i++){ */
                   11183:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11184:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11185:       /* } */
1.126     brouard  11186:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11187:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11188:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11189:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11190:     fclose (ficparo);
                   11191:     fclose (ficlog);
                   11192:     goto end;
                   11193:     exit(0);
1.220     brouard  11194:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11195:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11196:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11197:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11198:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11199:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11200:     hess=matrix(1,npar,1,npar);
1.220     brouard  11201:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11202:     /* Read guessed parameters */
1.126     brouard  11203:     /* Reads comments: lines beginning with '#' */
                   11204:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11205:       ungetc(c,ficpar);
                   11206:       fgets(line, MAXLINE, ficpar);
                   11207:       numlinepar++;
1.141     brouard  11208:       fputs(line,stdout);
1.126     brouard  11209:       fputs(line,ficparo);
                   11210:       fputs(line,ficlog);
                   11211:     }
                   11212:     ungetc(c,ficpar);
                   11213:     
                   11214:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11215:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11216:     for(i=1; i <=nlstate; i++){
1.234     brouard  11217:       j=0;
1.126     brouard  11218:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11219:        if(jj==i) continue;
                   11220:        j++;
1.292     brouard  11221:        while((c=getc(ficpar))=='#' && c!= EOF){
                   11222:          ungetc(c,ficpar);
                   11223:          fgets(line, MAXLINE, ficpar);
                   11224:          numlinepar++;
                   11225:          fputs(line,stdout);
                   11226:          fputs(line,ficparo);
                   11227:          fputs(line,ficlog);
                   11228:        }
                   11229:        ungetc(c,ficpar);
1.234     brouard  11230:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11231:        if ((i1 != i) || (j1 != jj)){
                   11232:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11233: It might be a problem of design; if ncovcol and the model are correct\n \
                   11234: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11235:          exit(1);
                   11236:        }
                   11237:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11238:        if(mle==1)
                   11239:          printf("%1d%1d",i,jj);
                   11240:        fprintf(ficlog,"%1d%1d",i,jj);
                   11241:        for(k=1; k<=ncovmodel;k++){
                   11242:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11243:          if(mle==1){
                   11244:            printf(" %lf",param[i][j][k]);
                   11245:            fprintf(ficlog," %lf",param[i][j][k]);
                   11246:          }
                   11247:          else
                   11248:            fprintf(ficlog," %lf",param[i][j][k]);
                   11249:          fprintf(ficparo," %lf",param[i][j][k]);
                   11250:        }
                   11251:        fscanf(ficpar,"\n");
                   11252:        numlinepar++;
                   11253:        if(mle==1)
                   11254:          printf("\n");
                   11255:        fprintf(ficlog,"\n");
                   11256:        fprintf(ficparo,"\n");
1.126     brouard  11257:       }
                   11258:     }  
                   11259:     fflush(ficlog);
1.234     brouard  11260:     
1.251     brouard  11261:     /* Reads parameters values */
1.126     brouard  11262:     p=param[1][1];
1.251     brouard  11263:     pstart=paramstart[1][1];
1.126     brouard  11264:     
                   11265:     /* Reads comments: lines beginning with '#' */
                   11266:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11267:       ungetc(c,ficpar);
                   11268:       fgets(line, MAXLINE, ficpar);
                   11269:       numlinepar++;
1.141     brouard  11270:       fputs(line,stdout);
1.126     brouard  11271:       fputs(line,ficparo);
                   11272:       fputs(line,ficlog);
                   11273:     }
                   11274:     ungetc(c,ficpar);
                   11275: 
                   11276:     for(i=1; i <=nlstate; i++){
                   11277:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11278:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11279:        if ( (i1-i) * (j1-j) != 0){
                   11280:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11281:          exit(1);
                   11282:        }
                   11283:        printf("%1d%1d",i,j);
                   11284:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11285:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11286:        for(k=1; k<=ncovmodel;k++){
                   11287:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11288:          printf(" %le",delti3[i][j][k]);
                   11289:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11290:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11291:        }
                   11292:        fscanf(ficpar,"\n");
                   11293:        numlinepar++;
                   11294:        printf("\n");
                   11295:        fprintf(ficparo,"\n");
                   11296:        fprintf(ficlog,"\n");
1.126     brouard  11297:       }
                   11298:     }
                   11299:     fflush(ficlog);
1.234     brouard  11300:     
1.145     brouard  11301:     /* Reads covariance matrix */
1.126     brouard  11302:     delti=delti3[1][1];
1.220     brouard  11303:                
                   11304:                
1.126     brouard  11305:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11306:                
1.126     brouard  11307:     /* Reads comments: lines beginning with '#' */
                   11308:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11309:       ungetc(c,ficpar);
                   11310:       fgets(line, MAXLINE, ficpar);
                   11311:       numlinepar++;
1.141     brouard  11312:       fputs(line,stdout);
1.126     brouard  11313:       fputs(line,ficparo);
                   11314:       fputs(line,ficlog);
                   11315:     }
                   11316:     ungetc(c,ficpar);
1.220     brouard  11317:                
1.126     brouard  11318:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11319:     hess=matrix(1,npar,1,npar);
1.131     brouard  11320:     for(i=1; i <=npar; i++)
                   11321:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11322:                
1.194     brouard  11323:     /* Scans npar lines */
1.126     brouard  11324:     for(i=1; i <=npar; i++){
1.226     brouard  11325:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11326:       if(count != 3){
1.226     brouard  11327:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11328: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11329: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11330:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11331: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11332: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11333:        exit(1);
1.220     brouard  11334:       }else{
1.226     brouard  11335:        if(mle==1)
                   11336:          printf("%1d%1d%d",i1,j1,jk);
                   11337:       }
                   11338:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11339:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11340:       for(j=1; j <=i; j++){
1.226     brouard  11341:        fscanf(ficpar," %le",&matcov[i][j]);
                   11342:        if(mle==1){
                   11343:          printf(" %.5le",matcov[i][j]);
                   11344:        }
                   11345:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11346:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11347:       }
                   11348:       fscanf(ficpar,"\n");
                   11349:       numlinepar++;
                   11350:       if(mle==1)
1.220     brouard  11351:                                printf("\n");
1.126     brouard  11352:       fprintf(ficlog,"\n");
                   11353:       fprintf(ficparo,"\n");
                   11354:     }
1.194     brouard  11355:     /* End of read covariance matrix npar lines */
1.126     brouard  11356:     for(i=1; i <=npar; i++)
                   11357:       for(j=i+1;j<=npar;j++)
1.226     brouard  11358:        matcov[i][j]=matcov[j][i];
1.126     brouard  11359:     
                   11360:     if(mle==1)
                   11361:       printf("\n");
                   11362:     fprintf(ficlog,"\n");
                   11363:     
                   11364:     fflush(ficlog);
                   11365:     
                   11366:   }    /* End of mle != -3 */
1.218     brouard  11367:   
1.186     brouard  11368:   /*  Main data
                   11369:    */
1.290     brouard  11370:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11371:   /* num=lvector(1,n); */
                   11372:   /* moisnais=vector(1,n); */
                   11373:   /* annais=vector(1,n); */
                   11374:   /* moisdc=vector(1,n); */
                   11375:   /* andc=vector(1,n); */
                   11376:   /* weight=vector(1,n); */
                   11377:   /* agedc=vector(1,n); */
                   11378:   /* cod=ivector(1,n); */
                   11379:   /* for(i=1;i<=n;i++){ */
                   11380:   num=lvector(firstobs,lastobs);
                   11381:   moisnais=vector(firstobs,lastobs);
                   11382:   annais=vector(firstobs,lastobs);
                   11383:   moisdc=vector(firstobs,lastobs);
                   11384:   andc=vector(firstobs,lastobs);
                   11385:   weight=vector(firstobs,lastobs);
                   11386:   agedc=vector(firstobs,lastobs);
                   11387:   cod=ivector(firstobs,lastobs);
                   11388:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11389:     num[i]=0;
                   11390:     moisnais[i]=0;
                   11391:     annais[i]=0;
                   11392:     moisdc[i]=0;
                   11393:     andc[i]=0;
                   11394:     agedc[i]=0;
                   11395:     cod[i]=0;
                   11396:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11397:   }
1.290     brouard  11398:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11399:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11400:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11401:   tab=ivector(1,NCOVMAX);
1.144     brouard  11402:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11403:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11404: 
1.136     brouard  11405:   /* Reads data from file datafile */
                   11406:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11407:     goto end;
                   11408: 
                   11409:   /* Calculation of the number of parameters from char model */
1.234     brouard  11410:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11411:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11412:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11413:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11414:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11415:   */
                   11416:   
                   11417:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11418:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11419:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11420:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11421:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11422:   TvarF=ivector(1,NCOVMAX); /*  */
                   11423:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11424:   TvarV=ivector(1,NCOVMAX); /*  */
                   11425:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11426:   TvarA=ivector(1,NCOVMAX); /*  */
                   11427:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11428:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11429:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11430:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11431:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11432:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11433:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11434:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11435:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11436: 
1.230     brouard  11437:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11438:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11439:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11440:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11441:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11442:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11443:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11444:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11445:   */
                   11446:   /* For model-covariate k tells which data-covariate to use but
                   11447:     because this model-covariate is a construction we invent a new column
                   11448:     ncovcol + k1
                   11449:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11450:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11451:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11452:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11453:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11454:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11455:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11456:   */
1.145     brouard  11457:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11458:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11459:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11460:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11461:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11462:                         4 covariates (3 plus signs)
                   11463:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11464:                      */  
1.230     brouard  11465:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11466:                                * individual dummy, fixed or varying:
                   11467:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11468:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11469:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11470:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11471:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11472:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11473:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11474:                                * individual quantitative, fixed or varying:
                   11475:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11476:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11477:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11478: /* Main decodemodel */
                   11479: 
1.187     brouard  11480: 
1.223     brouard  11481:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11482:     goto end;
                   11483: 
1.137     brouard  11484:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11485:     nbwarn++;
                   11486:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11487:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11488:   }
1.136     brouard  11489:     /*  if(mle==1){*/
1.137     brouard  11490:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11491:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11492:   }
                   11493: 
                   11494:     /*-calculation of age at interview from date of interview and age at death -*/
                   11495:   agev=matrix(1,maxwav,1,imx);
                   11496: 
                   11497:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11498:     goto end;
                   11499: 
1.126     brouard  11500: 
1.136     brouard  11501:   agegomp=(int)agemin;
1.290     brouard  11502:   free_vector(moisnais,firstobs,lastobs);
                   11503:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11504:   /* free_matrix(mint,1,maxwav,1,n);
                   11505:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11506:   /* free_vector(moisdc,1,n); */
                   11507:   /* free_vector(andc,1,n); */
1.145     brouard  11508:   /* */
                   11509:   
1.126     brouard  11510:   wav=ivector(1,imx);
1.214     brouard  11511:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11512:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11513:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11514:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11515:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11516:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11517:    
                   11518:   /* Concatenates waves */
1.214     brouard  11519:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11520:      Death is a valid wave (if date is known).
                   11521:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11522:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11523:      and mw[mi+1][i]. dh depends on stepm.
                   11524:   */
                   11525: 
1.126     brouard  11526:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11527:   /* Concatenates waves */
1.145     brouard  11528:  
1.290     brouard  11529:   free_vector(moisdc,firstobs,lastobs);
                   11530:   free_vector(andc,firstobs,lastobs);
1.215     brouard  11531: 
1.126     brouard  11532:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11533:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11534:   ncodemax[1]=1;
1.145     brouard  11535:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11536:   cptcoveff=0;
1.220     brouard  11537:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11538:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11539:   }
                   11540:   
                   11541:   ncovcombmax=pow(2,cptcoveff);
                   11542:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11543:   for(i=1;i<ncovcombmax;i++)
                   11544:     invalidvarcomb[i]=0;
                   11545:   
1.211     brouard  11546:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11547:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11548:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11549:   
1.200     brouard  11550:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11551:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11552:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11553:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11554:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11555:    * (currently 0 or 1) in the data.
                   11556:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11557:    * corresponding modality (h,j).
                   11558:    */
                   11559: 
1.145     brouard  11560:   h=0;
                   11561:   /*if (cptcovn > 0) */
1.126     brouard  11562:   m=pow(2,cptcoveff);
                   11563:  
1.144     brouard  11564:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11565:           * For k=4 covariates, h goes from 1 to m=2**k
                   11566:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11567:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11568:           *     h\k   1     2     3     4
1.143     brouard  11569:           *______________________________  
                   11570:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11571:           *     2     2     1     1     1
                   11572:           *     3 i=2 1     2     1     1
                   11573:           *     4     2     2     1     1
                   11574:           *     5 i=3 1 i=2 1     2     1
                   11575:           *     6     2     1     2     1
                   11576:           *     7 i=4 1     2     2     1
                   11577:           *     8     2     2     2     1
1.197     brouard  11578:           *     9 i=5 1 i=3 1 i=2 1     2
                   11579:           *    10     2     1     1     2
                   11580:           *    11 i=6 1     2     1     2
                   11581:           *    12     2     2     1     2
                   11582:           *    13 i=7 1 i=4 1     2     2    
                   11583:           *    14     2     1     2     2
                   11584:           *    15 i=8 1     2     2     2
                   11585:           *    16     2     2     2     2
1.143     brouard  11586:           */
1.212     brouard  11587:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11588:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11589:      * and the value of each covariate?
                   11590:      * V1=1, V2=1, V3=2, V4=1 ?
                   11591:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11592:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11593:      * In order to get the real value in the data, we use nbcode
                   11594:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11595:      * We are keeping this crazy system in order to be able (in the future?) 
                   11596:      * to have more than 2 values (0 or 1) for a covariate.
                   11597:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11598:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11599:      *              bbbbbbbb
                   11600:      *              76543210     
                   11601:      *   h-1        00000101 (6-1=5)
1.219     brouard  11602:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11603:      *           &
                   11604:      *     1        00000001 (1)
1.219     brouard  11605:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11606:      *          +1= 00000001 =1 
1.211     brouard  11607:      *
                   11608:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11609:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11610:      *    >>k'            11
                   11611:      *          &   00000001
                   11612:      *            = 00000001
                   11613:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11614:      * Reverse h=6 and m=16?
                   11615:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11616:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11617:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11618:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11619:      * V3=decodtabm(14,3,2**4)=2
                   11620:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11621:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11622:      *          &1 000000001
                   11623:      *           = 000000001
                   11624:      *         +1= 000000010 =2
                   11625:      *                  2211
                   11626:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11627:      *                  V3=2
1.220     brouard  11628:                 * codtabm and decodtabm are identical
1.211     brouard  11629:      */
                   11630: 
1.145     brouard  11631: 
                   11632:  free_ivector(Ndum,-1,NCOVMAX);
                   11633: 
                   11634: 
1.126     brouard  11635:     
1.186     brouard  11636:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11637:   strcpy(optionfilegnuplot,optionfilefiname);
                   11638:   if(mle==-3)
1.201     brouard  11639:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11640:   strcat(optionfilegnuplot,".gp");
                   11641: 
                   11642:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11643:     printf("Problem with file %s",optionfilegnuplot);
                   11644:   }
                   11645:   else{
1.204     brouard  11646:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11647:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11648:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11649:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11650:   }
                   11651:   /*  fclose(ficgp);*/
1.186     brouard  11652: 
                   11653: 
                   11654:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11655: 
                   11656:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11657:   if(mle==-3)
1.201     brouard  11658:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11659:   strcat(optionfilehtm,".htm");
                   11660:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11661:     printf("Problem with %s \n",optionfilehtm);
                   11662:     exit(0);
1.126     brouard  11663:   }
                   11664: 
                   11665:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11666:   strcat(optionfilehtmcov,"-cov.htm");
                   11667:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11668:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11669:   }
                   11670:   else{
                   11671:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11672: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11673: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11674:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11675:   }
                   11676: 
1.213     brouard  11677:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11678: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11679: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11680: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11681: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11682: \n\
                   11683: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11684:  <ul><li><h4>Parameter files</h4>\n\
                   11685:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11686:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11687:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11688:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11689:  - Date and time at start: %s</ul>\n",\
                   11690:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11691:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11692:          fileres,fileres,\
                   11693:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11694:   fflush(fichtm);
                   11695: 
                   11696:   strcpy(pathr,path);
                   11697:   strcat(pathr,optionfilefiname);
1.184     brouard  11698: #ifdef WIN32
                   11699:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11700: #else
1.126     brouard  11701:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11702: #endif
                   11703:          
1.126     brouard  11704:   
1.220     brouard  11705:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11706:                 and for any valid combination of covariates
1.126     brouard  11707:      and prints on file fileres'p'. */
1.251     brouard  11708:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11709:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11710: 
                   11711:   fprintf(fichtm,"\n");
1.286     brouard  11712:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11713:          ftol, stepm);
                   11714:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11715:   ncurrv=1;
                   11716:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11717:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11718:   ncurrv=i;
                   11719:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11720:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  11721:   ncurrv=i;
                   11722:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11723:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  11724:   ncurrv=i;
                   11725:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11726:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11727:           nlstate, ndeath, maxwav, mle, weightopt);
                   11728: 
                   11729:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11730: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11731: 
                   11732:   
                   11733:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11734: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11735: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11736:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11737:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11738:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11739:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11740:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11741:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11742: 
1.126     brouard  11743:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11744:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11745:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11746: 
                   11747:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11748:   /* For mortality only */
1.126     brouard  11749:   if (mle==-3){
1.136     brouard  11750:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11751:     for(i=1;i<=NDIM;i++)
                   11752:       for(j=1;j<=NDIM;j++)
                   11753:        ximort[i][j]=0.;
1.186     brouard  11754:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  11755:     cens=ivector(firstobs,lastobs);
                   11756:     ageexmed=vector(firstobs,lastobs);
                   11757:     agecens=vector(firstobs,lastobs);
                   11758:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  11759:                
1.126     brouard  11760:     for (i=1; i<=imx; i++){
                   11761:       dcwave[i]=-1;
                   11762:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11763:        if (s[m][i]>nlstate) {
                   11764:          dcwave[i]=m;
                   11765:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11766:          break;
                   11767:        }
1.126     brouard  11768:     }
1.226     brouard  11769:     
1.126     brouard  11770:     for (i=1; i<=imx; i++) {
                   11771:       if (wav[i]>0){
1.226     brouard  11772:        ageexmed[i]=agev[mw[1][i]][i];
                   11773:        j=wav[i];
                   11774:        agecens[i]=1.; 
                   11775:        
                   11776:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11777:          agecens[i]=agev[mw[j][i]][i];
                   11778:          cens[i]= 1;
                   11779:        }else if (ageexmed[i]< 1) 
                   11780:          cens[i]= -1;
                   11781:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11782:          cens[i]=0 ;
1.126     brouard  11783:       }
                   11784:       else cens[i]=-1;
                   11785:     }
                   11786:     
                   11787:     for (i=1;i<=NDIM;i++) {
                   11788:       for (j=1;j<=NDIM;j++)
1.226     brouard  11789:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11790:     }
                   11791:     
1.145     brouard  11792:     /*p[1]=0.0268; p[NDIM]=0.083;*/
1.126     brouard  11793:     /*printf("%lf %lf", p[1], p[2]);*/
                   11794:     
                   11795:     
1.136     brouard  11796: #ifdef GSL
                   11797:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11798: #else
1.126     brouard  11799:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11800: #endif
1.201     brouard  11801:     strcpy(filerespow,"POW-MORT_"); 
                   11802:     strcat(filerespow,fileresu);
1.126     brouard  11803:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11804:       printf("Problem with resultfile: %s\n", filerespow);
                   11805:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11806:     }
1.136     brouard  11807: #ifdef GSL
                   11808:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11809: #else
1.126     brouard  11810:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11811: #endif
1.126     brouard  11812:     /*  for (i=1;i<=nlstate;i++)
                   11813:        for(j=1;j<=nlstate+ndeath;j++)
                   11814:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11815:     */
                   11816:     fprintf(ficrespow,"\n");
1.136     brouard  11817: #ifdef GSL
                   11818:     /* gsl starts here */ 
                   11819:     T = gsl_multimin_fminimizer_nmsimplex;
                   11820:     gsl_multimin_fminimizer *sfm = NULL;
                   11821:     gsl_vector *ss, *x;
                   11822:     gsl_multimin_function minex_func;
                   11823: 
                   11824:     /* Initial vertex size vector */
                   11825:     ss = gsl_vector_alloc (NDIM);
                   11826:     
                   11827:     if (ss == NULL){
                   11828:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11829:     }
                   11830:     /* Set all step sizes to 1 */
                   11831:     gsl_vector_set_all (ss, 0.001);
                   11832: 
                   11833:     /* Starting point */
1.126     brouard  11834:     
1.136     brouard  11835:     x = gsl_vector_alloc (NDIM);
                   11836:     
                   11837:     if (x == NULL){
                   11838:       gsl_vector_free(ss);
                   11839:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11840:     }
                   11841:   
                   11842:     /* Initialize method and iterate */
                   11843:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11844:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11845:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11846:     gsl_vector_set(x, 0, p[1]);
                   11847:     gsl_vector_set(x, 1, p[2]);
                   11848: 
                   11849:     minex_func.f = &gompertz_f;
                   11850:     minex_func.n = NDIM;
                   11851:     minex_func.params = (void *)&p; /* ??? */
                   11852:     
                   11853:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11854:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11855:     
                   11856:     printf("Iterations beginning .....\n\n");
                   11857:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   11858: 
                   11859:     iteri=0;
                   11860:     while (rval == GSL_CONTINUE){
                   11861:       iteri++;
                   11862:       status = gsl_multimin_fminimizer_iterate(sfm);
                   11863:       
                   11864:       if (status) printf("error: %s\n", gsl_strerror (status));
                   11865:       fflush(0);
                   11866:       
                   11867:       if (status) 
                   11868:         break;
                   11869:       
                   11870:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   11871:       ssval = gsl_multimin_fminimizer_size (sfm);
                   11872:       
                   11873:       if (rval == GSL_SUCCESS)
                   11874:         printf ("converged to a local maximum at\n");
                   11875:       
                   11876:       printf("%5d ", iteri);
                   11877:       for (it = 0; it < NDIM; it++){
                   11878:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   11879:       }
                   11880:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   11881:     }
                   11882:     
                   11883:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   11884:     
                   11885:     gsl_vector_free(x); /* initial values */
                   11886:     gsl_vector_free(ss); /* inital step size */
                   11887:     for (it=0; it<NDIM; it++){
                   11888:       p[it+1]=gsl_vector_get(sfm->x,it);
                   11889:       fprintf(ficrespow," %.12lf", p[it]);
                   11890:     }
                   11891:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   11892: #endif
                   11893: #ifdef POWELL
                   11894:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   11895: #endif  
1.126     brouard  11896:     fclose(ficrespow);
                   11897:     
1.203     brouard  11898:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  11899: 
                   11900:     for(i=1; i <=NDIM; i++)
                   11901:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  11902:                                matcov[i][j]=matcov[j][i];
1.126     brouard  11903:     
                   11904:     printf("\nCovariance matrix\n ");
1.203     brouard  11905:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  11906:     for(i=1; i <=NDIM; i++) {
                   11907:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  11908:                                printf("%f ",matcov[i][j]);
                   11909:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  11910:       }
1.203     brouard  11911:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  11912:     }
                   11913:     
                   11914:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  11915:     for (i=1;i<=NDIM;i++) {
1.126     brouard  11916:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  11917:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   11918:     }
1.126     brouard  11919:     lsurv=vector(1,AGESUP);
                   11920:     lpop=vector(1,AGESUP);
                   11921:     tpop=vector(1,AGESUP);
                   11922:     lsurv[agegomp]=100000;
                   11923:     
                   11924:     for (k=agegomp;k<=AGESUP;k++) {
                   11925:       agemortsup=k;
                   11926:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   11927:     }
                   11928:     
                   11929:     for (k=agegomp;k<agemortsup;k++)
                   11930:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   11931:     
                   11932:     for (k=agegomp;k<agemortsup;k++){
                   11933:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   11934:       sumlpop=sumlpop+lpop[k];
                   11935:     }
                   11936:     
                   11937:     tpop[agegomp]=sumlpop;
                   11938:     for (k=agegomp;k<(agemortsup-3);k++){
                   11939:       /*  tpop[k+1]=2;*/
                   11940:       tpop[k+1]=tpop[k]-lpop[k];
                   11941:     }
                   11942:     
                   11943:     
                   11944:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   11945:     for (k=agegomp;k<(agemortsup-2);k++) 
                   11946:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   11947:     
                   11948:     
                   11949:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  11950:                ageminpar=50;
                   11951:                agemaxpar=100;
1.194     brouard  11952:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   11953:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11954: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11955: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   11956:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   11957: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   11958: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  11959:     }else{
                   11960:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   11961:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  11962:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  11963:                }
1.201     brouard  11964:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  11965:                     stepm, weightopt,\
                   11966:                     model,imx,p,matcov,agemortsup);
                   11967:     
                   11968:     free_vector(lsurv,1,AGESUP);
                   11969:     free_vector(lpop,1,AGESUP);
                   11970:     free_vector(tpop,1,AGESUP);
1.220     brouard  11971:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  11972:     free_ivector(dcwave,firstobs,lastobs);
                   11973:     free_vector(agecens,firstobs,lastobs);
                   11974:     free_vector(ageexmed,firstobs,lastobs);
                   11975:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  11976: #ifdef GSL
1.136     brouard  11977: #endif
1.186     brouard  11978:   } /* Endof if mle==-3 mortality only */
1.205     brouard  11979:   /* Standard  */
                   11980:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   11981:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11982:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  11983:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  11984:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   11985:     for (k=1; k<=npar;k++)
                   11986:       printf(" %d %8.5f",k,p[k]);
                   11987:     printf("\n");
1.205     brouard  11988:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   11989:       /* mlikeli uses func not funcone */
1.247     brouard  11990:       /* for(i=1;i<nlstate;i++){ */
                   11991:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11992:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11993:       /* } */
1.205     brouard  11994:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   11995:     }
                   11996:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   11997:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   11998:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   11999:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12000:     }
                   12001:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  12002:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12003:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12004:     for (k=1; k<=npar;k++)
                   12005:       printf(" %d %8.5f",k,p[k]);
                   12006:     printf("\n");
                   12007:     
                   12008:     /*--------- results files --------------*/
1.283     brouard  12009:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12010:     
                   12011:     
                   12012:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12013:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12014:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12015:     for(i=1,jk=1; i <=nlstate; i++){
                   12016:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12017:        if (k != i) {
                   12018:          printf("%d%d ",i,k);
                   12019:          fprintf(ficlog,"%d%d ",i,k);
                   12020:          fprintf(ficres,"%1d%1d ",i,k);
                   12021:          for(j=1; j <=ncovmodel; j++){
                   12022:            printf("%12.7f ",p[jk]);
                   12023:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12024:            fprintf(ficres,"%12.7f ",p[jk]);
                   12025:            jk++; 
                   12026:          }
                   12027:          printf("\n");
                   12028:          fprintf(ficlog,"\n");
                   12029:          fprintf(ficres,"\n");
                   12030:        }
1.126     brouard  12031:       }
                   12032:     }
1.203     brouard  12033:     if(mle != 0){
                   12034:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12035:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12036:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12037:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12038:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12039:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12040:        for(k=1; k <=(nlstate+ndeath); k++){
                   12041:          if (k != i) {
                   12042:            printf("%d%d ",i,k);
                   12043:            fprintf(ficlog,"%d%d ",i,k);
                   12044:            for(j=1; j <=ncovmodel; j++){
                   12045:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12046:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12047:              jk++; 
                   12048:            }
                   12049:            printf("\n");
                   12050:            fprintf(ficlog,"\n");
                   12051:          }
                   12052:        }
1.193     brouard  12053:       }
1.203     brouard  12054:     } /* end of hesscov and Wald tests */
1.225     brouard  12055:     
1.203     brouard  12056:     /*  */
1.126     brouard  12057:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12058:     printf("# Scales (for hessian or gradient estimation)\n");
                   12059:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12060:     for(i=1,jk=1; i <=nlstate; i++){
                   12061:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12062:        if (j!=i) {
                   12063:          fprintf(ficres,"%1d%1d",i,j);
                   12064:          printf("%1d%1d",i,j);
                   12065:          fprintf(ficlog,"%1d%1d",i,j);
                   12066:          for(k=1; k<=ncovmodel;k++){
                   12067:            printf(" %.5e",delti[jk]);
                   12068:            fprintf(ficlog," %.5e",delti[jk]);
                   12069:            fprintf(ficres," %.5e",delti[jk]);
                   12070:            jk++;
                   12071:          }
                   12072:          printf("\n");
                   12073:          fprintf(ficlog,"\n");
                   12074:          fprintf(ficres,"\n");
                   12075:        }
1.126     brouard  12076:       }
                   12077:     }
                   12078:     
                   12079:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12080:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12081:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12082:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12083:     /* # 121 Var(a12)\n\ */
                   12084:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12085:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12086:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12087:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12088:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12089:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12090:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12091:     
                   12092:     
                   12093:     /* Just to have a covariance matrix which will be more understandable
                   12094:        even is we still don't want to manage dictionary of variables
                   12095:     */
                   12096:     for(itimes=1;itimes<=2;itimes++){
                   12097:       jj=0;
                   12098:       for(i=1; i <=nlstate; i++){
1.225     brouard  12099:        for(j=1; j <=nlstate+ndeath; j++){
                   12100:          if(j==i) continue;
                   12101:          for(k=1; k<=ncovmodel;k++){
                   12102:            jj++;
                   12103:            ca[0]= k+'a'-1;ca[1]='\0';
                   12104:            if(itimes==1){
                   12105:              if(mle>=1)
                   12106:                printf("#%1d%1d%d",i,j,k);
                   12107:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12108:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12109:            }else{
                   12110:              if(mle>=1)
                   12111:                printf("%1d%1d%d",i,j,k);
                   12112:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12113:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12114:            }
                   12115:            ll=0;
                   12116:            for(li=1;li <=nlstate; li++){
                   12117:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12118:                if(lj==li) continue;
                   12119:                for(lk=1;lk<=ncovmodel;lk++){
                   12120:                  ll++;
                   12121:                  if(ll<=jj){
                   12122:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12123:                    if(ll<jj){
                   12124:                      if(itimes==1){
                   12125:                        if(mle>=1)
                   12126:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12127:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12128:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12129:                      }else{
                   12130:                        if(mle>=1)
                   12131:                          printf(" %.5e",matcov[jj][ll]); 
                   12132:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12133:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12134:                      }
                   12135:                    }else{
                   12136:                      if(itimes==1){
                   12137:                        if(mle>=1)
                   12138:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12139:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12140:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12141:                      }else{
                   12142:                        if(mle>=1)
                   12143:                          printf(" %.7e",matcov[jj][ll]); 
                   12144:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12145:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12146:                      }
                   12147:                    }
                   12148:                  }
                   12149:                } /* end lk */
                   12150:              } /* end lj */
                   12151:            } /* end li */
                   12152:            if(mle>=1)
                   12153:              printf("\n");
                   12154:            fprintf(ficlog,"\n");
                   12155:            fprintf(ficres,"\n");
                   12156:            numlinepar++;
                   12157:          } /* end k*/
                   12158:        } /*end j */
1.126     brouard  12159:       } /* end i */
                   12160:     } /* end itimes */
                   12161:     
                   12162:     fflush(ficlog);
                   12163:     fflush(ficres);
1.225     brouard  12164:     while(fgets(line, MAXLINE, ficpar)) {
                   12165:       /* If line starts with a # it is a comment */
                   12166:       if (line[0] == '#') {
                   12167:        numlinepar++;
                   12168:        fputs(line,stdout);
                   12169:        fputs(line,ficparo);
                   12170:        fputs(line,ficlog);
                   12171:        continue;
                   12172:       }else
                   12173:        break;
                   12174:     }
                   12175:     
1.209     brouard  12176:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12177:     /*   ungetc(c,ficpar); */
                   12178:     /*   fgets(line, MAXLINE, ficpar); */
                   12179:     /*   fputs(line,stdout); */
                   12180:     /*   fputs(line,ficparo); */
                   12181:     /* } */
                   12182:     /* ungetc(c,ficpar); */
1.126     brouard  12183:     
                   12184:     estepm=0;
1.209     brouard  12185:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12186:       
                   12187:       if (num_filled != 6) {
                   12188:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12189:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12190:        goto end;
                   12191:       }
                   12192:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12193:     }
                   12194:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12195:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12196:     
1.209     brouard  12197:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12198:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12199:     if (fage <= 2) {
                   12200:       bage = ageminpar;
                   12201:       fage = agemaxpar;
                   12202:     }
                   12203:     
                   12204:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12205:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12206:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12207:                
1.186     brouard  12208:     /* Other stuffs, more or less useful */    
1.254     brouard  12209:     while(fgets(line, MAXLINE, ficpar)) {
                   12210:       /* If line starts with a # it is a comment */
                   12211:       if (line[0] == '#') {
                   12212:        numlinepar++;
                   12213:        fputs(line,stdout);
                   12214:        fputs(line,ficparo);
                   12215:        fputs(line,ficlog);
                   12216:        continue;
                   12217:       }else
                   12218:        break;
                   12219:     }
                   12220: 
                   12221:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12222:       
                   12223:       if (num_filled != 7) {
                   12224:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12225:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12226:        goto end;
                   12227:       }
                   12228:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12229:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12230:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12231:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12232:     }
1.254     brouard  12233: 
                   12234:     while(fgets(line, MAXLINE, ficpar)) {
                   12235:       /* If line starts with a # it is a comment */
                   12236:       if (line[0] == '#') {
                   12237:        numlinepar++;
                   12238:        fputs(line,stdout);
                   12239:        fputs(line,ficparo);
                   12240:        fputs(line,ficlog);
                   12241:        continue;
                   12242:       }else
                   12243:        break;
1.126     brouard  12244:     }
                   12245:     
                   12246:     
                   12247:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12248:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12249:     
1.254     brouard  12250:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12251:       if (num_filled != 1) {
                   12252:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12253:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12254:        goto end;
                   12255:       }
                   12256:       printf("pop_based=%d\n",popbased);
                   12257:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12258:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12259:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12260:     }
                   12261:      
1.258     brouard  12262:     /* Results */
                   12263:     nresult=0;
                   12264:     do{
                   12265:       if(!fgets(line, MAXLINE, ficpar)){
                   12266:        endishere=1;
                   12267:        parameterline=14;
                   12268:       }else if (line[0] == '#') {
                   12269:        /* If line starts with a # it is a comment */
1.254     brouard  12270:        numlinepar++;
                   12271:        fputs(line,stdout);
                   12272:        fputs(line,ficparo);
                   12273:        fputs(line,ficlog);
                   12274:        continue;
1.258     brouard  12275:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12276:        parameterline=11;
                   12277:       else if(sscanf(line,"backcast=%[^\n]\n",modeltemp))
                   12278:        parameterline=12;
                   12279:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12280:        parameterline=13;
                   12281:       else{
                   12282:        parameterline=14;
1.254     brouard  12283:       }
1.258     brouard  12284:       switch (parameterline){ 
                   12285:       case 11:
                   12286:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF){
                   12287:          if (num_filled != 8) {
                   12288:            printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12289:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12290:            goto end;
                   12291:          }
                   12292:          fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12293:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12294:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12295:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12296:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12297:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12298:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
                   12299: 
1.258     brouard  12300:        }
1.254     brouard  12301:        break;
1.258     brouard  12302:       case 12:
                   12303:        /*fscanf(ficpar,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj);*/
                   12304:        if((num_filled=sscanf(line,"backcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&backcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF){
                   12305:          if (num_filled != 8) {
1.262     brouard  12306:            printf("Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12307:            fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:backcast=1 starting-back-date=1/1/1990 final-back-date=1/1/1970 mobil_average=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
1.258     brouard  12308:            goto end;
                   12309:          }
                   12310:          printf("backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12311:          fprintf(ficparo,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12312:          fprintf(ficlog,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12313:          fprintf(ficres,"backcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",backcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12314:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12315:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12316:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.258     brouard  12317:        }
1.230     brouard  12318:        break;
1.258     brouard  12319:       case 13:
                   12320:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12321:          if (num_filled == 0){
                   12322:            resultline[0]='\0';
                   12323:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12324:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12325:            break;
                   12326:          } else if (num_filled != 1){
                   12327:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12328:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12329:          }
                   12330:          nresult++; /* Sum of resultlines */
                   12331:          printf("Result %d: result=%s\n",nresult, resultline);
                   12332:          if(nresult > MAXRESULTLINES){
                   12333:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12334:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12335:            goto end;
                   12336:          }
                   12337:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12338:          fprintf(ficparo,"result: %s\n",resultline);
                   12339:          fprintf(ficres,"result: %s\n",resultline);
                   12340:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12341:          break;
1.258     brouard  12342:        case 14: 
1.259     brouard  12343:          if(ncovmodel >2 && nresult==0 ){
                   12344:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12345:            goto end;
                   12346:          }
1.259     brouard  12347:          break;
1.258     brouard  12348:        default:
                   12349:          nresult=1;
                   12350:          decoderesult(".",nresult ); /* No covariate */
                   12351:        }
                   12352:       } /* End switch parameterline */
                   12353:     }while(endishere==0); /* End do */
1.126     brouard  12354:     
1.230     brouard  12355:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12356:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12357:     
                   12358:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12359:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12360:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12361: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12362: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12363:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12364: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12365: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12366:     }else{
1.270     brouard  12367:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
                   12368:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, backcast, pathc,p, (int)anproj1-bage, (int)anback1-fage);
1.220     brouard  12369:     }
                   12370:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.258     brouard  12371:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,backcast, estepm, \
1.273     brouard  12372:                 jprev1,mprev1,anprev1,dateprev1, dateproj1, dateback1,jprev2,mprev2,anprev2,dateprev2,dateproj2, dateback2);
1.220     brouard  12373:                
1.225     brouard  12374:     /*------------ free_vector  -------------*/
                   12375:     /*  chdir(path); */
1.220     brouard  12376:                
1.215     brouard  12377:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12378:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12379:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12380:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12381:     free_lvector(num,firstobs,lastobs);
                   12382:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12383:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12384:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12385:     fclose(ficparo);
                   12386:     fclose(ficres);
1.220     brouard  12387:                
                   12388:                
1.186     brouard  12389:     /* Other results (useful)*/
1.220     brouard  12390:                
                   12391:                
1.126     brouard  12392:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12393:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12394:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12395:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12396:     fclose(ficrespl);
                   12397: 
                   12398:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12399:     /*#include "hpijx.h"*/
                   12400:     hPijx(p, bage, fage);
1.145     brouard  12401:     fclose(ficrespij);
1.227     brouard  12402:     
1.220     brouard  12403:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12404:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12405:     k=1;
1.126     brouard  12406:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12407:     
1.269     brouard  12408:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12409:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12410:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12411:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12412:        for(k=1;k<=ncovcombmax;k++)
                   12413:          probs[i][j][k]=0.;
1.269     brouard  12414:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12415:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12416:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12417:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12418:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12419:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12420:          for(k=1;k<=ncovcombmax;k++)
                   12421:            mobaverages[i][j][k]=0.;
1.219     brouard  12422:       mobaverage=mobaverages;
                   12423:       if (mobilav!=0) {
1.235     brouard  12424:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12425:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12426:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12427:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12428:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12429:        }
1.269     brouard  12430:       } else if (mobilavproj !=0) {
1.235     brouard  12431:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12432:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12433:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12434:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12435:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12436:        }
1.269     brouard  12437:       }else{
                   12438:        printf("Internal error moving average\n");
                   12439:        fflush(stdout);
                   12440:        exit(1);
1.219     brouard  12441:       }
                   12442:     }/* end if moving average */
1.227     brouard  12443:     
1.126     brouard  12444:     /*---------- Forecasting ------------------*/
                   12445:     if(prevfcast==1){
                   12446:       /*    if(stepm ==1){*/
1.269     brouard  12447:       prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
1.126     brouard  12448:     }
1.269     brouard  12449: 
                   12450:     /* Backcasting */
1.217     brouard  12451:     if(backcast==1){
1.219     brouard  12452:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12453:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12454:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12455: 
                   12456:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12457: 
                   12458:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12459: 
1.219     brouard  12460:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12461:       fclose(ficresplb);
                   12462: 
1.222     brouard  12463:       hBijx(p, bage, fage, mobaverage);
                   12464:       fclose(ficrespijb);
1.219     brouard  12465: 
1.269     brouard  12466:       prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2,
                   12467:                       mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff);
                   12468:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12469: 
                   12470:       
1.269     brouard  12471:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12472:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12473:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12474:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.269     brouard  12475:     }    /* end  Backcasting */
1.268     brouard  12476:  
1.186     brouard  12477:  
                   12478:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12479: 
1.215     brouard  12480:     free_ivector(wav,1,imx);
                   12481:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12482:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12483:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12484:                
                   12485:                
1.127     brouard  12486:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12487:                
1.201     brouard  12488:     strcpy(filerese,"E_");
                   12489:     strcat(filerese,fileresu);
1.126     brouard  12490:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12491:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12492:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12493:     }
1.208     brouard  12494:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12495:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12496: 
                   12497:     pstamp(ficreseij);
1.219     brouard  12498:                
1.235     brouard  12499:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12500:     if (cptcovn < 1){i1=1;}
                   12501:     
                   12502:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12503:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12504:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12505:        continue;
1.219     brouard  12506:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12507:       printf("\n#****** ");
1.225     brouard  12508:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12509:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12510:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12511:       }
                   12512:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12513:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12514:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12515:       }
                   12516:       fprintf(ficreseij,"******\n");
1.235     brouard  12517:       printf("******\n");
1.219     brouard  12518:       
                   12519:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12520:       oldm=oldms;savm=savms;
1.235     brouard  12521:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12522:       
1.219     brouard  12523:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12524:     }
                   12525:     fclose(ficreseij);
1.208     brouard  12526:     printf("done evsij\n");fflush(stdout);
                   12527:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12528: 
1.218     brouard  12529:                
1.227     brouard  12530:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12531:                
1.201     brouard  12532:     strcpy(filerest,"T_");
                   12533:     strcat(filerest,fileresu);
1.127     brouard  12534:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12535:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12536:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12537:     }
1.208     brouard  12538:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12539:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12540:     strcpy(fileresstde,"STDE_");
                   12541:     strcat(fileresstde,fileresu);
1.126     brouard  12542:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12543:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12544:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12545:     }
1.227     brouard  12546:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12547:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12548: 
1.201     brouard  12549:     strcpy(filerescve,"CVE_");
                   12550:     strcat(filerescve,fileresu);
1.126     brouard  12551:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12552:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12553:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12554:     }
1.227     brouard  12555:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12556:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12557: 
1.201     brouard  12558:     strcpy(fileresv,"V_");
                   12559:     strcat(fileresv,fileresu);
1.126     brouard  12560:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12561:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12562:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12563:     }
1.227     brouard  12564:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12565:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12566: 
1.235     brouard  12567:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12568:     if (cptcovn < 1){i1=1;}
                   12569:     
                   12570:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12571:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12572:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12573:        continue;
1.242     brouard  12574:       printf("\n#****** Result for:");
                   12575:       fprintf(ficrest,"\n#****** Result for:");
                   12576:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12577:       for(j=1;j<=cptcoveff;j++){ 
                   12578:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12579:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12580:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12581:       }
1.235     brouard  12582:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12583:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12584:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12585:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12586:       }        
1.208     brouard  12587:       fprintf(ficrest,"******\n");
1.227     brouard  12588:       fprintf(ficlog,"******\n");
                   12589:       printf("******\n");
1.208     brouard  12590:       
                   12591:       fprintf(ficresstdeij,"\n#****** ");
                   12592:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12593:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12594:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12595:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12596:       }
1.235     brouard  12597:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12598:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12599:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12600:       }        
1.208     brouard  12601:       fprintf(ficresstdeij,"******\n");
                   12602:       fprintf(ficrescveij,"******\n");
                   12603:       
                   12604:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12605:       /* pstamp(ficresvij); */
1.225     brouard  12606:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12607:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12608:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12609:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12610:       }        
1.208     brouard  12611:       fprintf(ficresvij,"******\n");
                   12612:       
                   12613:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12614:       oldm=oldms;savm=savms;
1.235     brouard  12615:       printf(" cvevsij ");
                   12616:       fprintf(ficlog, " cvevsij ");
                   12617:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12618:       printf(" end cvevsij \n ");
                   12619:       fprintf(ficlog, " end cvevsij \n ");
                   12620:       
                   12621:       /*
                   12622:        */
                   12623:       /* goto endfree; */
                   12624:       
                   12625:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12626:       pstamp(ficrest);
                   12627:       
1.269     brouard  12628:       epj=vector(1,nlstate+1);
1.208     brouard  12629:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12630:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12631:        cptcod= 0; /* To be deleted */
                   12632:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12633:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12634:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12635:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12636:        if(vpopbased==1)
                   12637:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12638:        else
1.288     brouard  12639:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12640:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12641:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12642:        fprintf(ficrest,"\n");
                   12643:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  12644:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   12645:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12646:        for(age=bage; age <=fage ;age++){
1.235     brouard  12647:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12648:          if (vpopbased==1) {
                   12649:            if(mobilav ==0){
                   12650:              for(i=1; i<=nlstate;i++)
                   12651:                prlim[i][i]=probs[(int)age][i][k];
                   12652:            }else{ /* mobilav */ 
                   12653:              for(i=1; i<=nlstate;i++)
                   12654:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12655:            }
                   12656:          }
1.219     brouard  12657:          
1.227     brouard  12658:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12659:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12660:          /* printf(" age %4.0f ",age); */
                   12661:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12662:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12663:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12664:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12665:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12666:            }
                   12667:            epj[nlstate+1] +=epj[j];
                   12668:          }
                   12669:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12670:          
1.227     brouard  12671:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12672:            for(j=1;j <=nlstate;j++)
                   12673:              vepp += vareij[i][j][(int)age];
                   12674:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12675:          for(j=1;j <=nlstate;j++){
                   12676:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12677:          }
                   12678:          fprintf(ficrest,"\n");
                   12679:        }
1.208     brouard  12680:       } /* End vpopbased */
1.269     brouard  12681:       free_vector(epj,1,nlstate+1);
1.208     brouard  12682:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12683:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12684:       printf("done selection\n");fflush(stdout);
                   12685:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12686:       
1.235     brouard  12687:     } /* End k selection */
1.227     brouard  12688: 
                   12689:     printf("done State-specific expectancies\n");fflush(stdout);
                   12690:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12691: 
1.288     brouard  12692:     /* variance-covariance of forward period prevalence*/
1.269     brouard  12693:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12694: 
1.227     brouard  12695:     
1.290     brouard  12696:     free_vector(weight,firstobs,lastobs);
1.227     brouard  12697:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  12698:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   12699:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   12700:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   12701:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  12702:     free_ivector(tab,1,NCOVMAX);
                   12703:     fclose(ficresstdeij);
                   12704:     fclose(ficrescveij);
                   12705:     fclose(ficresvij);
                   12706:     fclose(ficrest);
                   12707:     fclose(ficpar);
                   12708:     
                   12709:     
1.126     brouard  12710:     /*---------- End : free ----------------*/
1.219     brouard  12711:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12712:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12713:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12714:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12715:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12716:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12717:   /* endfree:*/
                   12718:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12719:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12720:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  12721:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   12722:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   12723:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   12724:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  12725:   free_matrix(matcov,1,npar,1,npar);
                   12726:   free_matrix(hess,1,npar,1,npar);
                   12727:   /*free_vector(delti,1,npar);*/
                   12728:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12729:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12730:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12731:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12732:   
                   12733:   free_ivector(ncodemax,1,NCOVMAX);
                   12734:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12735:   free_ivector(Dummy,-1,NCOVMAX);
                   12736:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12737:   free_ivector(DummyV,1,NCOVMAX);
                   12738:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12739:   free_ivector(Typevar,-1,NCOVMAX);
                   12740:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12741:   free_ivector(TvarsQ,1,NCOVMAX);
                   12742:   free_ivector(TvarsQind,1,NCOVMAX);
                   12743:   free_ivector(TvarsD,1,NCOVMAX);
                   12744:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12745:   free_ivector(TvarFD,1,NCOVMAX);
                   12746:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12747:   free_ivector(TvarF,1,NCOVMAX);
                   12748:   free_ivector(TvarFind,1,NCOVMAX);
                   12749:   free_ivector(TvarV,1,NCOVMAX);
                   12750:   free_ivector(TvarVind,1,NCOVMAX);
                   12751:   free_ivector(TvarA,1,NCOVMAX);
                   12752:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12753:   free_ivector(TvarFQ,1,NCOVMAX);
                   12754:   free_ivector(TvarFQind,1,NCOVMAX);
                   12755:   free_ivector(TvarVD,1,NCOVMAX);
                   12756:   free_ivector(TvarVDind,1,NCOVMAX);
                   12757:   free_ivector(TvarVQ,1,NCOVMAX);
                   12758:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12759:   free_ivector(Tvarsel,1,NCOVMAX);
                   12760:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12761:   free_ivector(Tposprod,1,NCOVMAX);
                   12762:   free_ivector(Tprod,1,NCOVMAX);
                   12763:   free_ivector(Tvaraff,1,NCOVMAX);
                   12764:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12765:   free_ivector(Tage,1,NCOVMAX);
                   12766:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12767:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12768:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12769:   
                   12770:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12771:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12772:   fflush(fichtm);
                   12773:   fflush(ficgp);
                   12774:   
1.227     brouard  12775:   
1.126     brouard  12776:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12777:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12778:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12779:   }else{
                   12780:     printf("End of Imach\n");
                   12781:     fprintf(ficlog,"End of Imach\n");
                   12782:   }
                   12783:   printf("See log file on %s\n",filelog);
                   12784:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12785:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12786:   rend_time = time(NULL);  
                   12787:   end_time = *localtime(&rend_time);
                   12788:   /* tml = *localtime(&end_time.tm_sec); */
                   12789:   strcpy(strtend,asctime(&end_time));
1.126     brouard  12790:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   12791:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  12792:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  12793:   
1.157     brouard  12794:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   12795:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   12796:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  12797:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   12798: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   12799:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12800:   fclose(fichtm);
                   12801:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   12802:   fclose(fichtmcov);
                   12803:   fclose(ficgp);
                   12804:   fclose(ficlog);
                   12805:   /*------ End -----------*/
1.227     brouard  12806:   
1.281     brouard  12807: 
                   12808: /* Executes gnuplot */
1.227     brouard  12809:   
                   12810:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  12811: #ifdef WIN32
1.227     brouard  12812:   if (_chdir(pathcd) != 0)
                   12813:     printf("Can't move to directory %s!\n",path);
                   12814:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  12815: #else
1.227     brouard  12816:     if(chdir(pathcd) != 0)
                   12817:       printf("Can't move to directory %s!\n", path);
                   12818:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  12819: #endif 
1.126     brouard  12820:     printf("Current directory %s!\n",pathcd);
                   12821:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   12822:   sprintf(plotcmd,"gnuplot");
1.157     brouard  12823: #ifdef _WIN32
1.126     brouard  12824:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   12825: #endif
                   12826:   if(!stat(plotcmd,&info)){
1.158     brouard  12827:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12828:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  12829:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  12830:     }else
                   12831:       strcpy(pplotcmd,plotcmd);
1.157     brouard  12832: #ifdef __unix
1.126     brouard  12833:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   12834:     if(!stat(plotcmd,&info)){
1.158     brouard  12835:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  12836:     }else
                   12837:       strcpy(pplotcmd,plotcmd);
                   12838: #endif
                   12839:   }else
                   12840:     strcpy(pplotcmd,plotcmd);
                   12841:   
                   12842:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  12843:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292     brouard  12844:   strcpy(pplotcmd,plotcmd);
1.227     brouard  12845:   
1.126     brouard  12846:   if((outcmd=system(plotcmd)) != 0){
1.292     brouard  12847:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  12848:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  12849:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292     brouard  12850:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  12851:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292     brouard  12852:       strcpy(plotcmd,pplotcmd);
                   12853:     }
1.126     brouard  12854:   }
1.158     brouard  12855:   printf(" Successful, please wait...");
1.126     brouard  12856:   while (z[0] != 'q') {
                   12857:     /* chdir(path); */
1.154     brouard  12858:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  12859:     scanf("%s",z);
                   12860: /*     if (z[0] == 'c') system("./imach"); */
                   12861:     if (z[0] == 'e') {
1.158     brouard  12862: #ifdef __APPLE__
1.152     brouard  12863:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  12864: #elif __linux
                   12865:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  12866: #else
1.152     brouard  12867:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  12868: #endif
                   12869:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   12870:       system(pplotcmd);
1.126     brouard  12871:     }
                   12872:     else if (z[0] == 'g') system(plotcmd);
                   12873:     else if (z[0] == 'q') exit(0);
                   12874:   }
1.227     brouard  12875: end:
1.126     brouard  12876:   while (z[0] != 'q') {
1.195     brouard  12877:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  12878:     scanf("%s",z);
                   12879:   }
1.283     brouard  12880:   printf("End\n");
1.282     brouard  12881:   exit(0);
1.126     brouard  12882: }

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