Annotation of imach/src/imach.c, revision 1.304

1.304   ! brouard     1: /* $Id: imach.c,v 1.303 2021/02/11 19:50:15 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.304   ! brouard     4:   Revision 1.303  2021/02/11 19:50:15  brouard
        !             5:   *  (Module): imach.c Someone entered 'results:' instead of 'result:'. Now it is an error which is printed.
        !             6: 
1.303     brouard     7:   Revision 1.302  2020/02/22 21:00:05  brouard
                      8:   *  (Module): imach.c Update mle=-3 (for computing Life expectancy
                      9:   and life table from the data without any state)
                     10: 
1.302     brouard    11:   Revision 1.301  2019/06/04 13:51:20  brouard
                     12:   Summary: Error in 'r'parameter file backcast yearsbproj instead of yearsfproj
                     13: 
1.301     brouard    14:   Revision 1.300  2019/05/22 19:09:45  brouard
                     15:   Summary: version 0.99r19 of May 2019
                     16: 
1.300     brouard    17:   Revision 1.299  2019/05/22 18:37:08  brouard
                     18:   Summary: Cleaned 0.99r19
                     19: 
1.299     brouard    20:   Revision 1.298  2019/05/22 18:19:56  brouard
                     21:   *** empty log message ***
                     22: 
1.298     brouard    23:   Revision 1.297  2019/05/22 17:56:10  brouard
                     24:   Summary: Fix bug by moving date2dmy and nhstepm which gaefin=-1
                     25: 
1.297     brouard    26:   Revision 1.296  2019/05/20 13:03:18  brouard
                     27:   Summary: Projection syntax simplified
                     28: 
                     29: 
                     30:   We can now start projections, forward or backward, from the mean date
                     31:   of inteviews up to or down to a number of years of projection:
                     32:   prevforecast=1 yearsfproj=15.3 mobil_average=0
                     33:   or
                     34:   prevforecast=1 starting-proj-date=1/1/2007 final-proj-date=12/31/2017 mobil_average=0
                     35:   or
                     36:   prevbackcast=1 yearsbproj=12.3 mobil_average=1
                     37:   or
                     38:   prevbackcast=1 starting-back-date=1/10/1999 final-back-date=1/1/1985 mobil_average=1
                     39: 
1.296     brouard    40:   Revision 1.295  2019/05/18 09:52:50  brouard
                     41:   Summary: doxygen tex bug
                     42: 
1.295     brouard    43:   Revision 1.294  2019/05/16 14:54:33  brouard
                     44:   Summary: There was some wrong lines added
                     45: 
1.294     brouard    46:   Revision 1.293  2019/05/09 15:17:34  brouard
                     47:   *** empty log message ***
                     48: 
1.293     brouard    49:   Revision 1.292  2019/05/09 14:17:20  brouard
                     50:   Summary: Some updates
                     51: 
1.292     brouard    52:   Revision 1.291  2019/05/09 13:44:18  brouard
                     53:   Summary: Before ncovmax
                     54: 
1.291     brouard    55:   Revision 1.290  2019/05/09 13:39:37  brouard
                     56:   Summary: 0.99r18 unlimited number of individuals
                     57: 
                     58:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                     59: 
1.290     brouard    60:   Revision 1.289  2018/12/13 09:16:26  brouard
                     61:   Summary: Bug for young ages (<-30) will be in r17
                     62: 
1.289     brouard    63:   Revision 1.288  2018/05/02 20:58:27  brouard
                     64:   Summary: Some bugs fixed
                     65: 
1.288     brouard    66:   Revision 1.287  2018/05/01 17:57:25  brouard
                     67:   Summary: Bug fixed by providing frequencies only for non missing covariates
                     68: 
1.287     brouard    69:   Revision 1.286  2018/04/27 14:27:04  brouard
                     70:   Summary: some minor bugs
                     71: 
1.286     brouard    72:   Revision 1.285  2018/04/21 21:02:16  brouard
                     73:   Summary: Some bugs fixed, valgrind tested
                     74: 
1.285     brouard    75:   Revision 1.284  2018/04/20 05:22:13  brouard
                     76:   Summary: Computing mean and stdeviation of fixed quantitative variables
                     77: 
1.284     brouard    78:   Revision 1.283  2018/04/19 14:49:16  brouard
                     79:   Summary: Some minor bugs fixed
                     80: 
1.283     brouard    81:   Revision 1.282  2018/02/27 22:50:02  brouard
                     82:   *** empty log message ***
                     83: 
1.282     brouard    84:   Revision 1.281  2018/02/27 19:25:23  brouard
                     85:   Summary: Adding second argument for quitting
                     86: 
1.281     brouard    87:   Revision 1.280  2018/02/21 07:58:13  brouard
                     88:   Summary: 0.99r15
                     89: 
                     90:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                     91: 
1.280     brouard    92:   Revision 1.279  2017/07/20 13:35:01  brouard
                     93:   Summary: temporary working
                     94: 
1.279     brouard    95:   Revision 1.278  2017/07/19 14:09:02  brouard
                     96:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                     97: 
1.278     brouard    98:   Revision 1.277  2017/07/17 08:53:49  brouard
                     99:   Summary: BOM files can be read now
                    100: 
1.277     brouard   101:   Revision 1.276  2017/06/30 15:48:31  brouard
                    102:   Summary: Graphs improvements
                    103: 
1.276     brouard   104:   Revision 1.275  2017/06/30 13:39:33  brouard
                    105:   Summary: Saito's color
                    106: 
1.275     brouard   107:   Revision 1.274  2017/06/29 09:47:08  brouard
                    108:   Summary: Version 0.99r14
                    109: 
1.274     brouard   110:   Revision 1.273  2017/06/27 11:06:02  brouard
                    111:   Summary: More documentation on projections
                    112: 
1.273     brouard   113:   Revision 1.272  2017/06/27 10:22:40  brouard
                    114:   Summary: Color of backprojection changed from 6 to 5(yellow)
                    115: 
1.272     brouard   116:   Revision 1.271  2017/06/27 10:17:50  brouard
                    117:   Summary: Some bug with rint
                    118: 
1.271     brouard   119:   Revision 1.270  2017/05/24 05:45:29  brouard
                    120:   *** empty log message ***
                    121: 
1.270     brouard   122:   Revision 1.269  2017/05/23 08:39:25  brouard
                    123:   Summary: Code into subroutine, cleanings
                    124: 
1.269     brouard   125:   Revision 1.268  2017/05/18 20:09:32  brouard
                    126:   Summary: backprojection and confidence intervals of backprevalence
                    127: 
1.268     brouard   128:   Revision 1.267  2017/05/13 10:25:05  brouard
                    129:   Summary: temporary save for backprojection
                    130: 
1.267     brouard   131:   Revision 1.266  2017/05/13 07:26:12  brouard
                    132:   Summary: Version 0.99r13 (improvements and bugs fixed)
                    133: 
1.266     brouard   134:   Revision 1.265  2017/04/26 16:22:11  brouard
                    135:   Summary: imach 0.99r13 Some bugs fixed
                    136: 
1.265     brouard   137:   Revision 1.264  2017/04/26 06:01:29  brouard
                    138:   Summary: Labels in graphs
                    139: 
1.264     brouard   140:   Revision 1.263  2017/04/24 15:23:15  brouard
                    141:   Summary: to save
                    142: 
1.263     brouard   143:   Revision 1.262  2017/04/18 16:48:12  brouard
                    144:   *** empty log message ***
                    145: 
1.262     brouard   146:   Revision 1.261  2017/04/05 10:14:09  brouard
                    147:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    148: 
1.261     brouard   149:   Revision 1.260  2017/04/04 17:46:59  brouard
                    150:   Summary: Gnuplot indexations fixed (humm)
                    151: 
1.260     brouard   152:   Revision 1.259  2017/04/04 13:01:16  brouard
                    153:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    154: 
1.259     brouard   155:   Revision 1.258  2017/04/03 10:17:47  brouard
                    156:   Summary: Version 0.99r12
                    157: 
                    158:   Some cleanings, conformed with updated documentation.
                    159: 
1.258     brouard   160:   Revision 1.257  2017/03/29 16:53:30  brouard
                    161:   Summary: Temp
                    162: 
1.257     brouard   163:   Revision 1.256  2017/03/27 05:50:23  brouard
                    164:   Summary: Temporary
                    165: 
1.256     brouard   166:   Revision 1.255  2017/03/08 16:02:28  brouard
                    167:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    168: 
1.255     brouard   169:   Revision 1.254  2017/03/08 07:13:00  brouard
                    170:   Summary: Fixing data parameter line
                    171: 
1.254     brouard   172:   Revision 1.253  2016/12/15 11:59:41  brouard
                    173:   Summary: 0.99 in progress
                    174: 
1.253     brouard   175:   Revision 1.252  2016/09/15 21:15:37  brouard
                    176:   *** empty log message ***
                    177: 
1.252     brouard   178:   Revision 1.251  2016/09/15 15:01:13  brouard
                    179:   Summary: not working
                    180: 
1.251     brouard   181:   Revision 1.250  2016/09/08 16:07:27  brouard
                    182:   Summary: continue
                    183: 
1.250     brouard   184:   Revision 1.249  2016/09/07 17:14:18  brouard
                    185:   Summary: Starting values from frequencies
                    186: 
1.249     brouard   187:   Revision 1.248  2016/09/07 14:10:18  brouard
                    188:   *** empty log message ***
                    189: 
1.248     brouard   190:   Revision 1.247  2016/09/02 11:11:21  brouard
                    191:   *** empty log message ***
                    192: 
1.247     brouard   193:   Revision 1.246  2016/09/02 08:49:22  brouard
                    194:   *** empty log message ***
                    195: 
1.246     brouard   196:   Revision 1.245  2016/09/02 07:25:01  brouard
                    197:   *** empty log message ***
                    198: 
1.245     brouard   199:   Revision 1.244  2016/09/02 07:17:34  brouard
                    200:   *** empty log message ***
                    201: 
1.244     brouard   202:   Revision 1.243  2016/09/02 06:45:35  brouard
                    203:   *** empty log message ***
                    204: 
1.243     brouard   205:   Revision 1.242  2016/08/30 15:01:20  brouard
                    206:   Summary: Fixing a lots
                    207: 
1.242     brouard   208:   Revision 1.241  2016/08/29 17:17:25  brouard
                    209:   Summary: gnuplot problem in Back projection to fix
                    210: 
1.241     brouard   211:   Revision 1.240  2016/08/29 07:53:18  brouard
                    212:   Summary: Better
                    213: 
1.240     brouard   214:   Revision 1.239  2016/08/26 15:51:03  brouard
                    215:   Summary: Improvement in Powell output in order to copy and paste
                    216: 
                    217:   Author:
                    218: 
1.239     brouard   219:   Revision 1.238  2016/08/26 14:23:35  brouard
                    220:   Summary: Starting tests of 0.99
                    221: 
1.238     brouard   222:   Revision 1.237  2016/08/26 09:20:19  brouard
                    223:   Summary: to valgrind
                    224: 
1.237     brouard   225:   Revision 1.236  2016/08/25 10:50:18  brouard
                    226:   *** empty log message ***
                    227: 
1.236     brouard   228:   Revision 1.235  2016/08/25 06:59:23  brouard
                    229:   *** empty log message ***
                    230: 
1.235     brouard   231:   Revision 1.234  2016/08/23 16:51:20  brouard
                    232:   *** empty log message ***
                    233: 
1.234     brouard   234:   Revision 1.233  2016/08/23 07:40:50  brouard
                    235:   Summary: not working
                    236: 
1.233     brouard   237:   Revision 1.232  2016/08/22 14:20:21  brouard
                    238:   Summary: not working
                    239: 
1.232     brouard   240:   Revision 1.231  2016/08/22 07:17:15  brouard
                    241:   Summary: not working
                    242: 
1.231     brouard   243:   Revision 1.230  2016/08/22 06:55:53  brouard
                    244:   Summary: Not working
                    245: 
1.230     brouard   246:   Revision 1.229  2016/07/23 09:45:53  brouard
                    247:   Summary: Completing for func too
                    248: 
1.229     brouard   249:   Revision 1.228  2016/07/22 17:45:30  brouard
                    250:   Summary: Fixing some arrays, still debugging
                    251: 
1.227     brouard   252:   Revision 1.226  2016/07/12 18:42:34  brouard
                    253:   Summary: temp
                    254: 
1.226     brouard   255:   Revision 1.225  2016/07/12 08:40:03  brouard
                    256:   Summary: saving but not running
                    257: 
1.225     brouard   258:   Revision 1.224  2016/07/01 13:16:01  brouard
                    259:   Summary: Fixes
                    260: 
1.224     brouard   261:   Revision 1.223  2016/02/19 09:23:35  brouard
                    262:   Summary: temporary
                    263: 
1.223     brouard   264:   Revision 1.222  2016/02/17 08:14:50  brouard
                    265:   Summary: Probably last 0.98 stable version 0.98r6
                    266: 
1.222     brouard   267:   Revision 1.221  2016/02/15 23:35:36  brouard
                    268:   Summary: minor bug
                    269: 
1.220     brouard   270:   Revision 1.219  2016/02/15 00:48:12  brouard
                    271:   *** empty log message ***
                    272: 
1.219     brouard   273:   Revision 1.218  2016/02/12 11:29:23  brouard
                    274:   Summary: 0.99 Back projections
                    275: 
1.218     brouard   276:   Revision 1.217  2015/12/23 17:18:31  brouard
                    277:   Summary: Experimental backcast
                    278: 
1.217     brouard   279:   Revision 1.216  2015/12/18 17:32:11  brouard
                    280:   Summary: 0.98r4 Warning and status=-2
                    281: 
                    282:   Version 0.98r4 is now:
                    283:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    284:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    285:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    286: 
1.216     brouard   287:   Revision 1.215  2015/12/16 08:52:24  brouard
                    288:   Summary: 0.98r4 working
                    289: 
1.215     brouard   290:   Revision 1.214  2015/12/16 06:57:54  brouard
                    291:   Summary: temporary not working
                    292: 
1.214     brouard   293:   Revision 1.213  2015/12/11 18:22:17  brouard
                    294:   Summary: 0.98r4
                    295: 
1.213     brouard   296:   Revision 1.212  2015/11/21 12:47:24  brouard
                    297:   Summary: minor typo
                    298: 
1.212     brouard   299:   Revision 1.211  2015/11/21 12:41:11  brouard
                    300:   Summary: 0.98r3 with some graph of projected cross-sectional
                    301: 
                    302:   Author: Nicolas Brouard
                    303: 
1.211     brouard   304:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   305:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   306:   Summary: Adding ftolpl parameter
                    307:   Author: N Brouard
                    308: 
                    309:   We had difficulties to get smoothed confidence intervals. It was due
                    310:   to the period prevalence which wasn't computed accurately. The inner
                    311:   parameter ftolpl is now an outer parameter of the .imach parameter
                    312:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    313:   computation are long.
                    314: 
1.209     brouard   315:   Revision 1.208  2015/11/17 14:31:57  brouard
                    316:   Summary: temporary
                    317: 
1.208     brouard   318:   Revision 1.207  2015/10/27 17:36:57  brouard
                    319:   *** empty log message ***
                    320: 
1.207     brouard   321:   Revision 1.206  2015/10/24 07:14:11  brouard
                    322:   *** empty log message ***
                    323: 
1.206     brouard   324:   Revision 1.205  2015/10/23 15:50:53  brouard
                    325:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    326: 
1.205     brouard   327:   Revision 1.204  2015/10/01 16:20:26  brouard
                    328:   Summary: Some new graphs of contribution to likelihood
                    329: 
1.204     brouard   330:   Revision 1.203  2015/09/30 17:45:14  brouard
                    331:   Summary: looking at better estimation of the hessian
                    332: 
                    333:   Also a better criteria for convergence to the period prevalence And
                    334:   therefore adding the number of years needed to converge. (The
                    335:   prevalence in any alive state shold sum to one
                    336: 
1.203     brouard   337:   Revision 1.202  2015/09/22 19:45:16  brouard
                    338:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    339: 
1.202     brouard   340:   Revision 1.201  2015/09/15 17:34:58  brouard
                    341:   Summary: 0.98r0
                    342: 
                    343:   - Some new graphs like suvival functions
                    344:   - Some bugs fixed like model=1+age+V2.
                    345: 
1.201     brouard   346:   Revision 1.200  2015/09/09 16:53:55  brouard
                    347:   Summary: Big bug thanks to Flavia
                    348: 
                    349:   Even model=1+age+V2. did not work anymore
                    350: 
1.200     brouard   351:   Revision 1.199  2015/09/07 14:09:23  brouard
                    352:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    353: 
1.199     brouard   354:   Revision 1.198  2015/09/03 07:14:39  brouard
                    355:   Summary: 0.98q5 Flavia
                    356: 
1.198     brouard   357:   Revision 1.197  2015/09/01 18:24:39  brouard
                    358:   *** empty log message ***
                    359: 
1.197     brouard   360:   Revision 1.196  2015/08/18 23:17:52  brouard
                    361:   Summary: 0.98q5
                    362: 
1.196     brouard   363:   Revision 1.195  2015/08/18 16:28:39  brouard
                    364:   Summary: Adding a hack for testing purpose
                    365: 
                    366:   After reading the title, ftol and model lines, if the comment line has
                    367:   a q, starting with #q, the answer at the end of the run is quit. It
                    368:   permits to run test files in batch with ctest. The former workaround was
                    369:   $ echo q | imach foo.imach
                    370: 
1.195     brouard   371:   Revision 1.194  2015/08/18 13:32:00  brouard
                    372:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    373: 
1.194     brouard   374:   Revision 1.193  2015/08/04 07:17:42  brouard
                    375:   Summary: 0.98q4
                    376: 
1.193     brouard   377:   Revision 1.192  2015/07/16 16:49:02  brouard
                    378:   Summary: Fixing some outputs
                    379: 
1.192     brouard   380:   Revision 1.191  2015/07/14 10:00:33  brouard
                    381:   Summary: Some fixes
                    382: 
1.191     brouard   383:   Revision 1.190  2015/05/05 08:51:13  brouard
                    384:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    385: 
                    386:   Fix 1+age+.
                    387: 
1.190     brouard   388:   Revision 1.189  2015/04/30 14:45:16  brouard
                    389:   Summary: 0.98q2
                    390: 
1.189     brouard   391:   Revision 1.188  2015/04/30 08:27:53  brouard
                    392:   *** empty log message ***
                    393: 
1.188     brouard   394:   Revision 1.187  2015/04/29 09:11:15  brouard
                    395:   *** empty log message ***
                    396: 
1.187     brouard   397:   Revision 1.186  2015/04/23 12:01:52  brouard
                    398:   Summary: V1*age is working now, version 0.98q1
                    399: 
                    400:   Some codes had been disabled in order to simplify and Vn*age was
                    401:   working in the optimization phase, ie, giving correct MLE parameters,
                    402:   but, as usual, outputs were not correct and program core dumped.
                    403: 
1.186     brouard   404:   Revision 1.185  2015/03/11 13:26:42  brouard
                    405:   Summary: Inclusion of compile and links command line for Intel Compiler
                    406: 
1.185     brouard   407:   Revision 1.184  2015/03/11 11:52:39  brouard
                    408:   Summary: Back from Windows 8. Intel Compiler
                    409: 
1.184     brouard   410:   Revision 1.183  2015/03/10 20:34:32  brouard
                    411:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    412: 
                    413:   We use directest instead of original Powell test; probably no
                    414:   incidence on the results, but better justifications;
                    415:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    416:   wrong results.
                    417: 
1.183     brouard   418:   Revision 1.182  2015/02/12 08:19:57  brouard
                    419:   Summary: Trying to keep directest which seems simpler and more general
                    420:   Author: Nicolas Brouard
                    421: 
1.182     brouard   422:   Revision 1.181  2015/02/11 23:22:24  brouard
                    423:   Summary: Comments on Powell added
                    424: 
                    425:   Author:
                    426: 
1.181     brouard   427:   Revision 1.180  2015/02/11 17:33:45  brouard
                    428:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    429: 
1.180     brouard   430:   Revision 1.179  2015/01/04 09:57:06  brouard
                    431:   Summary: back to OS/X
                    432: 
1.179     brouard   433:   Revision 1.178  2015/01/04 09:35:48  brouard
                    434:   *** empty log message ***
                    435: 
1.178     brouard   436:   Revision 1.177  2015/01/03 18:40:56  brouard
                    437:   Summary: Still testing ilc32 on OSX
                    438: 
1.177     brouard   439:   Revision 1.176  2015/01/03 16:45:04  brouard
                    440:   *** empty log message ***
                    441: 
1.176     brouard   442:   Revision 1.175  2015/01/03 16:33:42  brouard
                    443:   *** empty log message ***
                    444: 
1.175     brouard   445:   Revision 1.174  2015/01/03 16:15:49  brouard
                    446:   Summary: Still in cross-compilation
                    447: 
1.174     brouard   448:   Revision 1.173  2015/01/03 12:06:26  brouard
                    449:   Summary: trying to detect cross-compilation
                    450: 
1.173     brouard   451:   Revision 1.172  2014/12/27 12:07:47  brouard
                    452:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    453: 
1.172     brouard   454:   Revision 1.171  2014/12/23 13:26:59  brouard
                    455:   Summary: Back from Visual C
                    456: 
                    457:   Still problem with utsname.h on Windows
                    458: 
1.171     brouard   459:   Revision 1.170  2014/12/23 11:17:12  brouard
                    460:   Summary: Cleaning some \%% back to %%
                    461: 
                    462:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    463: 
1.170     brouard   464:   Revision 1.169  2014/12/22 23:08:31  brouard
                    465:   Summary: 0.98p
                    466: 
                    467:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    468: 
1.169     brouard   469:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   470:   Summary: update
1.169     brouard   471: 
1.168     brouard   472:   Revision 1.167  2014/12/22 13:50:56  brouard
                    473:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    474: 
                    475:   Testing on Linux 64
                    476: 
1.167     brouard   477:   Revision 1.166  2014/12/22 11:40:47  brouard
                    478:   *** empty log message ***
                    479: 
1.166     brouard   480:   Revision 1.165  2014/12/16 11:20:36  brouard
                    481:   Summary: After compiling on Visual C
                    482: 
                    483:   * imach.c (Module): Merging 1.61 to 1.162
                    484: 
1.165     brouard   485:   Revision 1.164  2014/12/16 10:52:11  brouard
                    486:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    487: 
                    488:   * imach.c (Module): Merging 1.61 to 1.162
                    489: 
1.164     brouard   490:   Revision 1.163  2014/12/16 10:30:11  brouard
                    491:   * imach.c (Module): Merging 1.61 to 1.162
                    492: 
1.163     brouard   493:   Revision 1.162  2014/09/25 11:43:39  brouard
                    494:   Summary: temporary backup 0.99!
                    495: 
1.162     brouard   496:   Revision 1.1  2014/09/16 11:06:58  brouard
                    497:   Summary: With some code (wrong) for nlopt
                    498: 
                    499:   Author:
                    500: 
                    501:   Revision 1.161  2014/09/15 20:41:41  brouard
                    502:   Summary: Problem with macro SQR on Intel compiler
                    503: 
1.161     brouard   504:   Revision 1.160  2014/09/02 09:24:05  brouard
                    505:   *** empty log message ***
                    506: 
1.160     brouard   507:   Revision 1.159  2014/09/01 10:34:10  brouard
                    508:   Summary: WIN32
                    509:   Author: Brouard
                    510: 
1.159     brouard   511:   Revision 1.158  2014/08/27 17:11:51  brouard
                    512:   *** empty log message ***
                    513: 
1.158     brouard   514:   Revision 1.157  2014/08/27 16:26:55  brouard
                    515:   Summary: Preparing windows Visual studio version
                    516:   Author: Brouard
                    517: 
                    518:   In order to compile on Visual studio, time.h is now correct and time_t
                    519:   and tm struct should be used. difftime should be used but sometimes I
                    520:   just make the differences in raw time format (time(&now).
                    521:   Trying to suppress #ifdef LINUX
                    522:   Add xdg-open for __linux in order to open default browser.
                    523: 
1.157     brouard   524:   Revision 1.156  2014/08/25 20:10:10  brouard
                    525:   *** empty log message ***
                    526: 
1.156     brouard   527:   Revision 1.155  2014/08/25 18:32:34  brouard
                    528:   Summary: New compile, minor changes
                    529:   Author: Brouard
                    530: 
1.155     brouard   531:   Revision 1.154  2014/06/20 17:32:08  brouard
                    532:   Summary: Outputs now all graphs of convergence to period prevalence
                    533: 
1.154     brouard   534:   Revision 1.153  2014/06/20 16:45:46  brouard
                    535:   Summary: If 3 live state, convergence to period prevalence on same graph
                    536:   Author: Brouard
                    537: 
1.153     brouard   538:   Revision 1.152  2014/06/18 17:54:09  brouard
                    539:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    540: 
1.152     brouard   541:   Revision 1.151  2014/06/18 16:43:30  brouard
                    542:   *** empty log message ***
                    543: 
1.151     brouard   544:   Revision 1.150  2014/06/18 16:42:35  brouard
                    545:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    546:   Author: brouard
                    547: 
1.150     brouard   548:   Revision 1.149  2014/06/18 15:51:14  brouard
                    549:   Summary: Some fixes in parameter files errors
                    550:   Author: Nicolas Brouard
                    551: 
1.149     brouard   552:   Revision 1.148  2014/06/17 17:38:48  brouard
                    553:   Summary: Nothing new
                    554:   Author: Brouard
                    555: 
                    556:   Just a new packaging for OS/X version 0.98nS
                    557: 
1.148     brouard   558:   Revision 1.147  2014/06/16 10:33:11  brouard
                    559:   *** empty log message ***
                    560: 
1.147     brouard   561:   Revision 1.146  2014/06/16 10:20:28  brouard
                    562:   Summary: Merge
                    563:   Author: Brouard
                    564: 
                    565:   Merge, before building revised version.
                    566: 
1.146     brouard   567:   Revision 1.145  2014/06/10 21:23:15  brouard
                    568:   Summary: Debugging with valgrind
                    569:   Author: Nicolas Brouard
                    570: 
                    571:   Lot of changes in order to output the results with some covariates
                    572:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    573:   improve the code.
                    574:   No more memory valgrind error but a lot has to be done in order to
                    575:   continue the work of splitting the code into subroutines.
                    576:   Also, decodemodel has been improved. Tricode is still not
                    577:   optimal. nbcode should be improved. Documentation has been added in
                    578:   the source code.
                    579: 
1.144     brouard   580:   Revision 1.143  2014/01/26 09:45:38  brouard
                    581:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    582: 
                    583:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    584:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    585: 
1.143     brouard   586:   Revision 1.142  2014/01/26 03:57:36  brouard
                    587:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    588: 
                    589:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    590: 
1.142     brouard   591:   Revision 1.141  2014/01/26 02:42:01  brouard
                    592:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    593: 
1.141     brouard   594:   Revision 1.140  2011/09/02 10:37:54  brouard
                    595:   Summary: times.h is ok with mingw32 now.
                    596: 
1.140     brouard   597:   Revision 1.139  2010/06/14 07:50:17  brouard
                    598:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    599:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    600: 
1.139     brouard   601:   Revision 1.138  2010/04/30 18:19:40  brouard
                    602:   *** empty log message ***
                    603: 
1.138     brouard   604:   Revision 1.137  2010/04/29 18:11:38  brouard
                    605:   (Module): Checking covariates for more complex models
                    606:   than V1+V2. A lot of change to be done. Unstable.
                    607: 
1.137     brouard   608:   Revision 1.136  2010/04/26 20:30:53  brouard
                    609:   (Module): merging some libgsl code. Fixing computation
                    610:   of likelione (using inter/intrapolation if mle = 0) in order to
                    611:   get same likelihood as if mle=1.
                    612:   Some cleaning of code and comments added.
                    613: 
1.136     brouard   614:   Revision 1.135  2009/10/29 15:33:14  brouard
                    615:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    616: 
1.135     brouard   617:   Revision 1.134  2009/10/29 13:18:53  brouard
                    618:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    619: 
1.134     brouard   620:   Revision 1.133  2009/07/06 10:21:25  brouard
                    621:   just nforces
                    622: 
1.133     brouard   623:   Revision 1.132  2009/07/06 08:22:05  brouard
                    624:   Many tings
                    625: 
1.132     brouard   626:   Revision 1.131  2009/06/20 16:22:47  brouard
                    627:   Some dimensions resccaled
                    628: 
1.131     brouard   629:   Revision 1.130  2009/05/26 06:44:34  brouard
                    630:   (Module): Max Covariate is now set to 20 instead of 8. A
                    631:   lot of cleaning with variables initialized to 0. Trying to make
                    632:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    633: 
1.130     brouard   634:   Revision 1.129  2007/08/31 13:49:27  lievre
                    635:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    636: 
1.129     lievre    637:   Revision 1.128  2006/06/30 13:02:05  brouard
                    638:   (Module): Clarifications on computing e.j
                    639: 
1.128     brouard   640:   Revision 1.127  2006/04/28 18:11:50  brouard
                    641:   (Module): Yes the sum of survivors was wrong since
                    642:   imach-114 because nhstepm was no more computed in the age
                    643:   loop. Now we define nhstepma in the age loop.
                    644:   (Module): In order to speed up (in case of numerous covariates) we
                    645:   compute health expectancies (without variances) in a first step
                    646:   and then all the health expectancies with variances or standard
                    647:   deviation (needs data from the Hessian matrices) which slows the
                    648:   computation.
                    649:   In the future we should be able to stop the program is only health
                    650:   expectancies and graph are needed without standard deviations.
                    651: 
1.127     brouard   652:   Revision 1.126  2006/04/28 17:23:28  brouard
                    653:   (Module): Yes the sum of survivors was wrong since
                    654:   imach-114 because nhstepm was no more computed in the age
                    655:   loop. Now we define nhstepma in the age loop.
                    656:   Version 0.98h
                    657: 
1.126     brouard   658:   Revision 1.125  2006/04/04 15:20:31  lievre
                    659:   Errors in calculation of health expectancies. Age was not initialized.
                    660:   Forecasting file added.
                    661: 
                    662:   Revision 1.124  2006/03/22 17:13:53  lievre
                    663:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    664:   The log-likelihood is printed in the log file
                    665: 
                    666:   Revision 1.123  2006/03/20 10:52:43  brouard
                    667:   * imach.c (Module): <title> changed, corresponds to .htm file
                    668:   name. <head> headers where missing.
                    669: 
                    670:   * imach.c (Module): Weights can have a decimal point as for
                    671:   English (a comma might work with a correct LC_NUMERIC environment,
                    672:   otherwise the weight is truncated).
                    673:   Modification of warning when the covariates values are not 0 or
                    674:   1.
                    675:   Version 0.98g
                    676: 
                    677:   Revision 1.122  2006/03/20 09:45:41  brouard
                    678:   (Module): Weights can have a decimal point as for
                    679:   English (a comma might work with a correct LC_NUMERIC environment,
                    680:   otherwise the weight is truncated).
                    681:   Modification of warning when the covariates values are not 0 or
                    682:   1.
                    683:   Version 0.98g
                    684: 
                    685:   Revision 1.121  2006/03/16 17:45:01  lievre
                    686:   * imach.c (Module): Comments concerning covariates added
                    687: 
                    688:   * imach.c (Module): refinements in the computation of lli if
                    689:   status=-2 in order to have more reliable computation if stepm is
                    690:   not 1 month. Version 0.98f
                    691: 
                    692:   Revision 1.120  2006/03/16 15:10:38  lievre
                    693:   (Module): refinements in the computation of lli if
                    694:   status=-2 in order to have more reliable computation if stepm is
                    695:   not 1 month. Version 0.98f
                    696: 
                    697:   Revision 1.119  2006/03/15 17:42:26  brouard
                    698:   (Module): Bug if status = -2, the loglikelihood was
                    699:   computed as likelihood omitting the logarithm. Version O.98e
                    700: 
                    701:   Revision 1.118  2006/03/14 18:20:07  brouard
                    702:   (Module): varevsij Comments added explaining the second
                    703:   table of variances if popbased=1 .
                    704:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    705:   (Module): Function pstamp added
                    706:   (Module): Version 0.98d
                    707: 
                    708:   Revision 1.117  2006/03/14 17:16:22  brouard
                    709:   (Module): varevsij Comments added explaining the second
                    710:   table of variances if popbased=1 .
                    711:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    712:   (Module): Function pstamp added
                    713:   (Module): Version 0.98d
                    714: 
                    715:   Revision 1.116  2006/03/06 10:29:27  brouard
                    716:   (Module): Variance-covariance wrong links and
                    717:   varian-covariance of ej. is needed (Saito).
                    718: 
                    719:   Revision 1.115  2006/02/27 12:17:45  brouard
                    720:   (Module): One freematrix added in mlikeli! 0.98c
                    721: 
                    722:   Revision 1.114  2006/02/26 12:57:58  brouard
                    723:   (Module): Some improvements in processing parameter
                    724:   filename with strsep.
                    725: 
                    726:   Revision 1.113  2006/02/24 14:20:24  brouard
                    727:   (Module): Memory leaks checks with valgrind and:
                    728:   datafile was not closed, some imatrix were not freed and on matrix
                    729:   allocation too.
                    730: 
                    731:   Revision 1.112  2006/01/30 09:55:26  brouard
                    732:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    733: 
                    734:   Revision 1.111  2006/01/25 20:38:18  brouard
                    735:   (Module): Lots of cleaning and bugs added (Gompertz)
                    736:   (Module): Comments can be added in data file. Missing date values
                    737:   can be a simple dot '.'.
                    738: 
                    739:   Revision 1.110  2006/01/25 00:51:50  brouard
                    740:   (Module): Lots of cleaning and bugs added (Gompertz)
                    741: 
                    742:   Revision 1.109  2006/01/24 19:37:15  brouard
                    743:   (Module): Comments (lines starting with a #) are allowed in data.
                    744: 
                    745:   Revision 1.108  2006/01/19 18:05:42  lievre
                    746:   Gnuplot problem appeared...
                    747:   To be fixed
                    748: 
                    749:   Revision 1.107  2006/01/19 16:20:37  brouard
                    750:   Test existence of gnuplot in imach path
                    751: 
                    752:   Revision 1.106  2006/01/19 13:24:36  brouard
                    753:   Some cleaning and links added in html output
                    754: 
                    755:   Revision 1.105  2006/01/05 20:23:19  lievre
                    756:   *** empty log message ***
                    757: 
                    758:   Revision 1.104  2005/09/30 16:11:43  lievre
                    759:   (Module): sump fixed, loop imx fixed, and simplifications.
                    760:   (Module): If the status is missing at the last wave but we know
                    761:   that the person is alive, then we can code his/her status as -2
                    762:   (instead of missing=-1 in earlier versions) and his/her
                    763:   contributions to the likelihood is 1 - Prob of dying from last
                    764:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    765:   the healthy state at last known wave). Version is 0.98
                    766: 
                    767:   Revision 1.103  2005/09/30 15:54:49  lievre
                    768:   (Module): sump fixed, loop imx fixed, and simplifications.
                    769: 
                    770:   Revision 1.102  2004/09/15 17:31:30  brouard
                    771:   Add the possibility to read data file including tab characters.
                    772: 
                    773:   Revision 1.101  2004/09/15 10:38:38  brouard
                    774:   Fix on curr_time
                    775: 
                    776:   Revision 1.100  2004/07/12 18:29:06  brouard
                    777:   Add version for Mac OS X. Just define UNIX in Makefile
                    778: 
                    779:   Revision 1.99  2004/06/05 08:57:40  brouard
                    780:   *** empty log message ***
                    781: 
                    782:   Revision 1.98  2004/05/16 15:05:56  brouard
                    783:   New version 0.97 . First attempt to estimate force of mortality
                    784:   directly from the data i.e. without the need of knowing the health
                    785:   state at each age, but using a Gompertz model: log u =a + b*age .
                    786:   This is the basic analysis of mortality and should be done before any
                    787:   other analysis, in order to test if the mortality estimated from the
                    788:   cross-longitudinal survey is different from the mortality estimated
                    789:   from other sources like vital statistic data.
                    790: 
                    791:   The same imach parameter file can be used but the option for mle should be -3.
                    792: 
1.133     brouard   793:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   794:   former routines in order to include the new code within the former code.
                    795: 
                    796:   The output is very simple: only an estimate of the intercept and of
                    797:   the slope with 95% confident intervals.
                    798: 
                    799:   Current limitations:
                    800:   A) Even if you enter covariates, i.e. with the
                    801:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    802:   B) There is no computation of Life Expectancy nor Life Table.
                    803: 
                    804:   Revision 1.97  2004/02/20 13:25:42  lievre
                    805:   Version 0.96d. Population forecasting command line is (temporarily)
                    806:   suppressed.
                    807: 
                    808:   Revision 1.96  2003/07/15 15:38:55  brouard
                    809:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    810:   rewritten within the same printf. Workaround: many printfs.
                    811: 
                    812:   Revision 1.95  2003/07/08 07:54:34  brouard
                    813:   * imach.c (Repository):
                    814:   (Repository): Using imachwizard code to output a more meaningful covariance
                    815:   matrix (cov(a12,c31) instead of numbers.
                    816: 
                    817:   Revision 1.94  2003/06/27 13:00:02  brouard
                    818:   Just cleaning
                    819: 
                    820:   Revision 1.93  2003/06/25 16:33:55  brouard
                    821:   (Module): On windows (cygwin) function asctime_r doesn't
                    822:   exist so I changed back to asctime which exists.
                    823:   (Module): Version 0.96b
                    824: 
                    825:   Revision 1.92  2003/06/25 16:30:45  brouard
                    826:   (Module): On windows (cygwin) function asctime_r doesn't
                    827:   exist so I changed back to asctime which exists.
                    828: 
                    829:   Revision 1.91  2003/06/25 15:30:29  brouard
                    830:   * imach.c (Repository): Duplicated warning errors corrected.
                    831:   (Repository): Elapsed time after each iteration is now output. It
                    832:   helps to forecast when convergence will be reached. Elapsed time
                    833:   is stamped in powell.  We created a new html file for the graphs
                    834:   concerning matrix of covariance. It has extension -cov.htm.
                    835: 
                    836:   Revision 1.90  2003/06/24 12:34:15  brouard
                    837:   (Module): Some bugs corrected for windows. Also, when
                    838:   mle=-1 a template is output in file "or"mypar.txt with the design
                    839:   of the covariance matrix to be input.
                    840: 
                    841:   Revision 1.89  2003/06/24 12:30:52  brouard
                    842:   (Module): Some bugs corrected for windows. Also, when
                    843:   mle=-1 a template is output in file "or"mypar.txt with the design
                    844:   of the covariance matrix to be input.
                    845: 
                    846:   Revision 1.88  2003/06/23 17:54:56  brouard
                    847:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    848: 
                    849:   Revision 1.87  2003/06/18 12:26:01  brouard
                    850:   Version 0.96
                    851: 
                    852:   Revision 1.86  2003/06/17 20:04:08  brouard
                    853:   (Module): Change position of html and gnuplot routines and added
                    854:   routine fileappend.
                    855: 
                    856:   Revision 1.85  2003/06/17 13:12:43  brouard
                    857:   * imach.c (Repository): Check when date of death was earlier that
                    858:   current date of interview. It may happen when the death was just
                    859:   prior to the death. In this case, dh was negative and likelihood
                    860:   was wrong (infinity). We still send an "Error" but patch by
                    861:   assuming that the date of death was just one stepm after the
                    862:   interview.
                    863:   (Repository): Because some people have very long ID (first column)
                    864:   we changed int to long in num[] and we added a new lvector for
                    865:   memory allocation. But we also truncated to 8 characters (left
                    866:   truncation)
                    867:   (Repository): No more line truncation errors.
                    868: 
                    869:   Revision 1.84  2003/06/13 21:44:43  brouard
                    870:   * imach.c (Repository): Replace "freqsummary" at a correct
                    871:   place. It differs from routine "prevalence" which may be called
                    872:   many times. Probs is memory consuming and must be used with
                    873:   parcimony.
                    874:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    875: 
                    876:   Revision 1.83  2003/06/10 13:39:11  lievre
                    877:   *** empty log message ***
                    878: 
                    879:   Revision 1.82  2003/06/05 15:57:20  brouard
                    880:   Add log in  imach.c and  fullversion number is now printed.
                    881: 
                    882: */
                    883: /*
                    884:    Interpolated Markov Chain
                    885: 
                    886:   Short summary of the programme:
                    887:   
1.227     brouard   888:   This program computes Healthy Life Expectancies or State-specific
                    889:   (if states aren't health statuses) Expectancies from
                    890:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    891: 
                    892:   -1- a first survey ("cross") where individuals from different ages
                    893:   are interviewed on their health status or degree of disability (in
                    894:   the case of a health survey which is our main interest)
                    895: 
                    896:   -2- at least a second wave of interviews ("longitudinal") which
                    897:   measure each change (if any) in individual health status.  Health
                    898:   expectancies are computed from the time spent in each health state
                    899:   according to a model. More health states you consider, more time is
                    900:   necessary to reach the Maximum Likelihood of the parameters involved
                    901:   in the model.  The simplest model is the multinomial logistic model
                    902:   where pij is the probability to be observed in state j at the second
                    903:   wave conditional to be observed in state i at the first
                    904:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    905:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    906:   have a more complex model than "constant and age", you should modify
                    907:   the program where the markup *Covariates have to be included here
                    908:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   909:   convergence.
                    910: 
                    911:   The advantage of this computer programme, compared to a simple
                    912:   multinomial logistic model, is clear when the delay between waves is not
                    913:   identical for each individual. Also, if a individual missed an
                    914:   intermediate interview, the information is lost, but taken into
                    915:   account using an interpolation or extrapolation.  
                    916: 
                    917:   hPijx is the probability to be observed in state i at age x+h
                    918:   conditional to the observed state i at age x. The delay 'h' can be
                    919:   split into an exact number (nh*stepm) of unobserved intermediate
                    920:   states. This elementary transition (by month, quarter,
                    921:   semester or year) is modelled as a multinomial logistic.  The hPx
                    922:   matrix is simply the matrix product of nh*stepm elementary matrices
                    923:   and the contribution of each individual to the likelihood is simply
                    924:   hPijx.
                    925: 
                    926:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   927:   of the life expectancies. It also computes the period (stable) prevalence.
                    928: 
                    929: Back prevalence and projections:
1.227     brouard   930: 
                    931:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    932:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    933:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    934:    mobilavproj)
                    935: 
                    936:     Computes the back prevalence limit for any combination of
                    937:     covariate values k at any age between ageminpar and agemaxpar and
                    938:     returns it in **bprlim. In the loops,
                    939: 
                    940:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    941:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    942: 
                    943:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   944:    Computes for any combination of covariates k and any age between bage and fage 
                    945:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    946:                        oldm=oldms;savm=savms;
1.227     brouard   947: 
1.267     brouard   948:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   949:      Computes the transition matrix starting at age 'age' over
                    950:      'nhstepm*hstepm*stepm' months (i.e. until
                    951:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   952:      nhstepm*hstepm matrices. 
                    953: 
                    954:      Returns p3mat[i][j][h] after calling
                    955:      p3mat[i][j][h]=matprod2(newm,
                    956:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    957:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    958:      oldm);
1.226     brouard   959: 
                    960: Important routines
                    961: 
                    962: - func (or funcone), computes logit (pij) distinguishing
                    963:   o fixed variables (single or product dummies or quantitative);
                    964:   o varying variables by:
                    965:    (1) wave (single, product dummies, quantitative), 
                    966:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    967:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    968:        % varying dummy (not done) or quantitative (not done);
                    969: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    970:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    971: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    972:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    973:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   974: 
1.226     brouard   975: 
                    976:   
1.133     brouard   977:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    978:            Institut national d'études démographiques, Paris.
1.126     brouard   979:   This software have been partly granted by Euro-REVES, a concerted action
                    980:   from the European Union.
                    981:   It is copyrighted identically to a GNU software product, ie programme and
                    982:   software can be distributed freely for non commercial use. Latest version
                    983:   can be accessed at http://euroreves.ined.fr/imach .
                    984: 
                    985:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                    986:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                    987:   
                    988:   **********************************************************************/
                    989: /*
                    990:   main
                    991:   read parameterfile
                    992:   read datafile
                    993:   concatwav
                    994:   freqsummary
                    995:   if (mle >= 1)
                    996:     mlikeli
                    997:   print results files
                    998:   if mle==1 
                    999:      computes hessian
                   1000:   read end of parameter file: agemin, agemax, bage, fage, estepm
                   1001:       begin-prev-date,...
                   1002:   open gnuplot file
                   1003:   open html file
1.145     brouard  1004:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                   1005:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                   1006:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                   1007:     freexexit2 possible for memory heap.
                   1008: 
                   1009:   h Pij x                         | pij_nom  ficrestpij
                   1010:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                   1011:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                   1012:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                   1013: 
                   1014:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                   1015:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                   1016:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                   1017:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                   1018:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                   1019: 
1.126     brouard  1020:   forecasting if prevfcast==1 prevforecast call prevalence()
                   1021:   health expectancies
                   1022:   Variance-covariance of DFLE
                   1023:   prevalence()
                   1024:    movingaverage()
                   1025:   varevsij() 
                   1026:   if popbased==1 varevsij(,popbased)
                   1027:   total life expectancies
                   1028:   Variance of period (stable) prevalence
                   1029:  end
                   1030: */
                   1031: 
1.187     brouard  1032: /* #define DEBUG */
                   1033: /* #define DEBUGBRENT */
1.203     brouard  1034: /* #define DEBUGLINMIN */
                   1035: /* #define DEBUGHESS */
                   1036: #define DEBUGHESSIJ
1.224     brouard  1037: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard  1038: #define POWELL /* Instead of NLOPT */
1.224     brouard  1039: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard  1040: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                   1041: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard  1042: 
                   1043: #include <math.h>
                   1044: #include <stdio.h>
                   1045: #include <stdlib.h>
                   1046: #include <string.h>
1.226     brouard  1047: #include <ctype.h>
1.159     brouard  1048: 
                   1049: #ifdef _WIN32
                   1050: #include <io.h>
1.172     brouard  1051: #include <windows.h>
                   1052: #include <tchar.h>
1.159     brouard  1053: #else
1.126     brouard  1054: #include <unistd.h>
1.159     brouard  1055: #endif
1.126     brouard  1056: 
                   1057: #include <limits.h>
                   1058: #include <sys/types.h>
1.171     brouard  1059: 
                   1060: #if defined(__GNUC__)
                   1061: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1062: #endif
                   1063: 
1.126     brouard  1064: #include <sys/stat.h>
                   1065: #include <errno.h>
1.159     brouard  1066: /* extern int errno; */
1.126     brouard  1067: 
1.157     brouard  1068: /* #ifdef LINUX */
                   1069: /* #include <time.h> */
                   1070: /* #include "timeval.h" */
                   1071: /* #else */
                   1072: /* #include <sys/time.h> */
                   1073: /* #endif */
                   1074: 
1.126     brouard  1075: #include <time.h>
                   1076: 
1.136     brouard  1077: #ifdef GSL
                   1078: #include <gsl/gsl_errno.h>
                   1079: #include <gsl/gsl_multimin.h>
                   1080: #endif
                   1081: 
1.167     brouard  1082: 
1.162     brouard  1083: #ifdef NLOPT
                   1084: #include <nlopt.h>
                   1085: typedef struct {
                   1086:   double (* function)(double [] );
                   1087: } myfunc_data ;
                   1088: #endif
                   1089: 
1.126     brouard  1090: /* #include <libintl.h> */
                   1091: /* #define _(String) gettext (String) */
                   1092: 
1.251     brouard  1093: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1094: 
                   1095: #define GNUPLOTPROGRAM "gnuplot"
                   1096: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1097: #define FILENAMELENGTH 132
                   1098: 
                   1099: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1100: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1101: 
1.144     brouard  1102: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1103: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1104: 
                   1105: #define NINTERVMAX 8
1.144     brouard  1106: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1107: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.291     brouard  1108: #define NCOVMAX 20  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1109: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1110: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1111: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1112: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1113: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1114: /* #define AGESUP 130 */
1.288     brouard  1115: /* #define AGESUP 150 */
                   1116: #define AGESUP 200
1.268     brouard  1117: #define AGEINF 0
1.218     brouard  1118: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1119: #define AGEBASE 40
1.194     brouard  1120: #define AGEOVERFLOW 1.e20
1.164     brouard  1121: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1122: #ifdef _WIN32
                   1123: #define DIRSEPARATOR '\\'
                   1124: #define CHARSEPARATOR "\\"
                   1125: #define ODIRSEPARATOR '/'
                   1126: #else
1.126     brouard  1127: #define DIRSEPARATOR '/'
                   1128: #define CHARSEPARATOR "/"
                   1129: #define ODIRSEPARATOR '\\'
                   1130: #endif
                   1131: 
1.304   ! brouard  1132: /* $Id: imach.c,v 1.303 2021/02/11 19:50:15 brouard Exp $ */
1.126     brouard  1133: /* $State: Exp $ */
1.196     brouard  1134: #include "version.h"
                   1135: char version[]=__IMACH_VERSION__;
1.300     brouard  1136: char copyright[]="May 2019,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2020";
1.304   ! brouard  1137: char fullversion[]="$Revision: 1.303 $ $Date: 2021/02/11 19:50:15 $"; 
1.126     brouard  1138: char strstart[80];
                   1139: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1140: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1141: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1142: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1143: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1144: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1145: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1146: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1147: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1148: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1149: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1150: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1151: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1152: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1153: int nsd=0; /**< Total number of single dummy variables (output) */
                   1154: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1155: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1156: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1157: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1158: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1159: int cptcov=0; /* Working variable */
1.290     brouard  1160: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1161: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.302     brouard  1162: int npar=NPARMAX; /* Number of parameters (nlstate+ndeath-1)*nlstate*ncovmodel; */
1.126     brouard  1163: int nlstate=2; /* Number of live states */
                   1164: int ndeath=1; /* Number of dead states */
1.130     brouard  1165: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1166: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1167: int popbased=0;
                   1168: 
                   1169: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1170: int maxwav=0; /* Maxim number of waves */
                   1171: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1172: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1173: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1174:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1175: int mle=1, weightopt=0;
1.126     brouard  1176: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1177: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1178: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1179:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1180: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1181: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1182: 
1.130     brouard  1183: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1184: double **matprod2(); /* test */
1.126     brouard  1185: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1186: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1187: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1188: 
1.136     brouard  1189: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1190: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1191: FILE *ficlog, *ficrespow;
1.130     brouard  1192: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1193: double fretone; /* Only one call to likelihood */
1.130     brouard  1194: long ipmx=0; /* Number of contributions */
1.126     brouard  1195: double sw; /* Sum of weights */
                   1196: char filerespow[FILENAMELENGTH];
                   1197: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1198: FILE *ficresilk;
                   1199: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1200: FILE *ficresprobmorprev;
                   1201: FILE *fichtm, *fichtmcov; /* Html File */
                   1202: FILE *ficreseij;
                   1203: char filerese[FILENAMELENGTH];
                   1204: FILE *ficresstdeij;
                   1205: char fileresstde[FILENAMELENGTH];
                   1206: FILE *ficrescveij;
                   1207: char filerescve[FILENAMELENGTH];
                   1208: FILE  *ficresvij;
                   1209: char fileresv[FILENAMELENGTH];
1.269     brouard  1210: 
1.126     brouard  1211: char title[MAXLINE];
1.234     brouard  1212: char model[MAXLINE]; /**< The model line */
1.217     brouard  1213: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1214: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1215: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1216: char command[FILENAMELENGTH];
                   1217: int  outcmd=0;
                   1218: 
1.217     brouard  1219: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1220: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1221: char filelog[FILENAMELENGTH]; /* Log file */
                   1222: char filerest[FILENAMELENGTH];
                   1223: char fileregp[FILENAMELENGTH];
                   1224: char popfile[FILENAMELENGTH];
                   1225: 
                   1226: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1227: 
1.157     brouard  1228: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1229: /* struct timezone tzp; */
                   1230: /* extern int gettimeofday(); */
                   1231: struct tm tml, *gmtime(), *localtime();
                   1232: 
                   1233: extern time_t time();
                   1234: 
                   1235: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1236: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1237: struct tm tm;
                   1238: 
1.126     brouard  1239: char strcurr[80], strfor[80];
                   1240: 
                   1241: char *endptr;
                   1242: long lval;
                   1243: double dval;
                   1244: 
                   1245: #define NR_END 1
                   1246: #define FREE_ARG char*
                   1247: #define FTOL 1.0e-10
                   1248: 
                   1249: #define NRANSI 
1.240     brouard  1250: #define ITMAX 200
                   1251: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1252: 
                   1253: #define TOL 2.0e-4 
                   1254: 
                   1255: #define CGOLD 0.3819660 
                   1256: #define ZEPS 1.0e-10 
                   1257: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1258: 
                   1259: #define GOLD 1.618034 
                   1260: #define GLIMIT 100.0 
                   1261: #define TINY 1.0e-20 
                   1262: 
                   1263: static double maxarg1,maxarg2;
                   1264: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1265: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1266:   
                   1267: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1268: #define rint(a) floor(a+0.5)
1.166     brouard  1269: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1270: #define mytinydouble 1.0e-16
1.166     brouard  1271: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1272: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1273: /* static double dsqrarg; */
                   1274: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1275: static double sqrarg;
                   1276: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1277: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1278: int agegomp= AGEGOMP;
                   1279: 
                   1280: int imx; 
                   1281: int stepm=1;
                   1282: /* Stepm, step in month: minimum step interpolation*/
                   1283: 
                   1284: int estepm;
                   1285: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1286: 
                   1287: int m,nb;
                   1288: long *num;
1.197     brouard  1289: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1290: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1291:                   covariate for which somebody answered excluding 
                   1292:                   undefined. Usually 2: 0 and 1. */
                   1293: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1294:                             covariate for which somebody answered including 
                   1295:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1296: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1297: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1298: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1299: double *ageexmed,*agecens;
                   1300: double dateintmean=0;
1.296     brouard  1301:   double anprojd, mprojd, jprojd; /* For eventual projections */
                   1302:   double anprojf, mprojf, jprojf;
1.126     brouard  1303: 
1.296     brouard  1304:   double anbackd, mbackd, jbackd; /* For eventual backprojections */
                   1305:   double anbackf, mbackf, jbackf;
                   1306:   double jintmean,mintmean,aintmean;  
1.126     brouard  1307: double *weight;
                   1308: int **s; /* Status */
1.141     brouard  1309: double *agedc;
1.145     brouard  1310: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1311:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1312:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1313: double **coqvar; /* Fixed quantitative covariate nqv */
                   1314: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1315: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1316: double  idx; 
                   1317: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1318: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1319: /*k          1  2   3   4     5    6    7     8    9 */
                   1320: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1321: /* Tndvar[k]    1   2   3               4          5 */
                   1322: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1323: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1324: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1325: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1326: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1327: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1328: /* Tprod[i]=k           4               7            */
                   1329: /* Tage[i]=k                  5               8      */
                   1330: /* */
                   1331: /* Type                    */
                   1332: /* V         1  2  3  4  5 */
                   1333: /*           F  F  V  V  V */
                   1334: /*           D  Q  D  D  Q */
                   1335: /*                         */
                   1336: int *TvarsD;
                   1337: int *TvarsDind;
                   1338: int *TvarsQ;
                   1339: int *TvarsQind;
                   1340: 
1.235     brouard  1341: #define MAXRESULTLINES 10
                   1342: int nresult=0;
1.258     brouard  1343: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1344: int TKresult[MAXRESULTLINES];
1.237     brouard  1345: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1346: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1347: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1348: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1349: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1350: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1351: 
1.234     brouard  1352: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1353: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1354: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1355: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1356: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1357: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1358: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1359: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1360: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1361: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1362: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1363: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1364: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1365: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1366: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1367: 
1.230     brouard  1368: int *Tvarsel; /**< Selected covariates for output */
                   1369: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1370: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1371: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1372: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1373: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1374: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1375: int *Tage;
1.227     brouard  1376: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1377: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1378: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1379: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1380: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1381: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1382: int **Tvard;
                   1383: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1384: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1385: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1386:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1387:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1388: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1389: double *lsurv, *lpop, *tpop;
                   1390: 
1.231     brouard  1391: #define FD 1; /* Fixed dummy covariate */
                   1392: #define FQ 2; /* Fixed quantitative covariate */
                   1393: #define FP 3; /* Fixed product covariate */
                   1394: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1395: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1396: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1397: #define VD 10; /* Varying dummy covariate */
                   1398: #define VQ 11; /* Varying quantitative covariate */
                   1399: #define VP 12; /* Varying product covariate */
                   1400: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1401: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1402: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1403: #define APFD 16; /* Age product * fixed dummy covariate */
                   1404: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1405: #define APVD 18; /* Age product * varying dummy covariate */
                   1406: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1407: 
                   1408: #define FTYPE 1; /* Fixed covariate */
                   1409: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1410: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1411: 
                   1412: struct kmodel{
                   1413:        int maintype; /* main type */
                   1414:        int subtype; /* subtype */
                   1415: };
                   1416: struct kmodel modell[NCOVMAX];
                   1417: 
1.143     brouard  1418: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1419: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1420: 
                   1421: /**************** split *************************/
                   1422: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1423: {
                   1424:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1425:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1426:   */ 
                   1427:   char *ss;                            /* pointer */
1.186     brouard  1428:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1429: 
                   1430:   l1 = strlen(path );                  /* length of path */
                   1431:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1432:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1433:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1434:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1435:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1436:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1437:     /* get current working directory */
                   1438:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1439: #ifdef WIN32
                   1440:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1441: #else
                   1442:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1443: #endif
1.126     brouard  1444:       return( GLOCK_ERROR_GETCWD );
                   1445:     }
                   1446:     /* got dirc from getcwd*/
                   1447:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1448:   } else {                             /* strip directory from path */
1.126     brouard  1449:     ss++;                              /* after this, the filename */
                   1450:     l2 = strlen( ss );                 /* length of filename */
                   1451:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1452:     strcpy( name, ss );                /* save file name */
                   1453:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1454:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1455:     printf(" DIRC2 = %s \n",dirc);
                   1456:   }
                   1457:   /* We add a separator at the end of dirc if not exists */
                   1458:   l1 = strlen( dirc );                 /* length of directory */
                   1459:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1460:     dirc[l1] =  DIRSEPARATOR;
                   1461:     dirc[l1+1] = 0; 
                   1462:     printf(" DIRC3 = %s \n",dirc);
                   1463:   }
                   1464:   ss = strrchr( name, '.' );           /* find last / */
                   1465:   if (ss >0){
                   1466:     ss++;
                   1467:     strcpy(ext,ss);                    /* save extension */
                   1468:     l1= strlen( name);
                   1469:     l2= strlen(ss)+1;
                   1470:     strncpy( finame, name, l1-l2);
                   1471:     finame[l1-l2]= 0;
                   1472:   }
                   1473: 
                   1474:   return( 0 );                         /* we're done */
                   1475: }
                   1476: 
                   1477: 
                   1478: /******************************************/
                   1479: 
                   1480: void replace_back_to_slash(char *s, char*t)
                   1481: {
                   1482:   int i;
                   1483:   int lg=0;
                   1484:   i=0;
                   1485:   lg=strlen(t);
                   1486:   for(i=0; i<= lg; i++) {
                   1487:     (s[i] = t[i]);
                   1488:     if (t[i]== '\\') s[i]='/';
                   1489:   }
                   1490: }
                   1491: 
1.132     brouard  1492: char *trimbb(char *out, char *in)
1.137     brouard  1493: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1494:   char *s;
                   1495:   s=out;
                   1496:   while (*in != '\0'){
1.137     brouard  1497:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1498:       in++;
                   1499:     }
                   1500:     *out++ = *in++;
                   1501:   }
                   1502:   *out='\0';
                   1503:   return s;
                   1504: }
                   1505: 
1.187     brouard  1506: /* char *substrchaine(char *out, char *in, char *chain) */
                   1507: /* { */
                   1508: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1509: /*   char *s, *t; */
                   1510: /*   t=in;s=out; */
                   1511: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1512: /*     *out++ = *in++; */
                   1513: /*   } */
                   1514: 
                   1515: /*   /\* *in matches *chain *\/ */
                   1516: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1517: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1518: /*   } */
                   1519: /*   in--; chain--; */
                   1520: /*   while ( (*in != '\0')){ */
                   1521: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1522: /*     *out++ = *in++; */
                   1523: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1524: /*   } */
                   1525: /*   *out='\0'; */
                   1526: /*   out=s; */
                   1527: /*   return out; */
                   1528: /* } */
                   1529: char *substrchaine(char *out, char *in, char *chain)
                   1530: {
                   1531:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1532:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1533: 
                   1534:   char *strloc;
                   1535: 
                   1536:   strcpy (out, in); 
                   1537:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1538:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1539:   if(strloc != NULL){ 
                   1540:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1541:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1542:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1543:   }
                   1544:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1545:   return out;
                   1546: }
                   1547: 
                   1548: 
1.145     brouard  1549: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1550: {
1.187     brouard  1551:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1552:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1553:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1554:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1555:   */
1.160     brouard  1556:   char *s, *t;
1.145     brouard  1557:   t=in;s=in;
                   1558:   while ((*in != occ) && (*in != '\0')){
                   1559:     *alocc++ = *in++;
                   1560:   }
                   1561:   if( *in == occ){
                   1562:     *(alocc)='\0';
                   1563:     s=++in;
                   1564:   }
                   1565:  
                   1566:   if (s == t) {/* occ not found */
                   1567:     *(alocc-(in-s))='\0';
                   1568:     in=s;
                   1569:   }
                   1570:   while ( *in != '\0'){
                   1571:     *blocc++ = *in++;
                   1572:   }
                   1573: 
                   1574:   *blocc='\0';
                   1575:   return t;
                   1576: }
1.137     brouard  1577: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1578: {
1.187     brouard  1579:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1580:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1581:      gives blocc="abcdef2ghi" and alocc="j".
                   1582:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1583:   */
                   1584:   char *s, *t;
                   1585:   t=in;s=in;
                   1586:   while (*in != '\0'){
                   1587:     while( *in == occ){
                   1588:       *blocc++ = *in++;
                   1589:       s=in;
                   1590:     }
                   1591:     *blocc++ = *in++;
                   1592:   }
                   1593:   if (s == t) /* occ not found */
                   1594:     *(blocc-(in-s))='\0';
                   1595:   else
                   1596:     *(blocc-(in-s)-1)='\0';
                   1597:   in=s;
                   1598:   while ( *in != '\0'){
                   1599:     *alocc++ = *in++;
                   1600:   }
                   1601: 
                   1602:   *alocc='\0';
                   1603:   return s;
                   1604: }
                   1605: 
1.126     brouard  1606: int nbocc(char *s, char occ)
                   1607: {
                   1608:   int i,j=0;
                   1609:   int lg=20;
                   1610:   i=0;
                   1611:   lg=strlen(s);
                   1612:   for(i=0; i<= lg; i++) {
1.234     brouard  1613:     if  (s[i] == occ ) j++;
1.126     brouard  1614:   }
                   1615:   return j;
                   1616: }
                   1617: 
1.137     brouard  1618: /* void cutv(char *u,char *v, char*t, char occ) */
                   1619: /* { */
                   1620: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1621: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1622: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1623: /*   int i,lg,j,p=0; */
                   1624: /*   i=0; */
                   1625: /*   lg=strlen(t); */
                   1626: /*   for(j=0; j<=lg-1; j++) { */
                   1627: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1628: /*   } */
1.126     brouard  1629: 
1.137     brouard  1630: /*   for(j=0; j<p; j++) { */
                   1631: /*     (u[j] = t[j]); */
                   1632: /*   } */
                   1633: /*      u[p]='\0'; */
1.126     brouard  1634: 
1.137     brouard  1635: /*    for(j=0; j<= lg; j++) { */
                   1636: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1637: /*   } */
                   1638: /* } */
1.126     brouard  1639: 
1.160     brouard  1640: #ifdef _WIN32
                   1641: char * strsep(char **pp, const char *delim)
                   1642: {
                   1643:   char *p, *q;
                   1644:          
                   1645:   if ((p = *pp) == NULL)
                   1646:     return 0;
                   1647:   if ((q = strpbrk (p, delim)) != NULL)
                   1648:   {
                   1649:     *pp = q + 1;
                   1650:     *q = '\0';
                   1651:   }
                   1652:   else
                   1653:     *pp = 0;
                   1654:   return p;
                   1655: }
                   1656: #endif
                   1657: 
1.126     brouard  1658: /********************** nrerror ********************/
                   1659: 
                   1660: void nrerror(char error_text[])
                   1661: {
                   1662:   fprintf(stderr,"ERREUR ...\n");
                   1663:   fprintf(stderr,"%s\n",error_text);
                   1664:   exit(EXIT_FAILURE);
                   1665: }
                   1666: /*********************** vector *******************/
                   1667: double *vector(int nl, int nh)
                   1668: {
                   1669:   double *v;
                   1670:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1671:   if (!v) nrerror("allocation failure in vector");
                   1672:   return v-nl+NR_END;
                   1673: }
                   1674: 
                   1675: /************************ free vector ******************/
                   1676: void free_vector(double*v, int nl, int nh)
                   1677: {
                   1678:   free((FREE_ARG)(v+nl-NR_END));
                   1679: }
                   1680: 
                   1681: /************************ivector *******************************/
                   1682: int *ivector(long nl,long nh)
                   1683: {
                   1684:   int *v;
                   1685:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1686:   if (!v) nrerror("allocation failure in ivector");
                   1687:   return v-nl+NR_END;
                   1688: }
                   1689: 
                   1690: /******************free ivector **************************/
                   1691: void free_ivector(int *v, long nl, long nh)
                   1692: {
                   1693:   free((FREE_ARG)(v+nl-NR_END));
                   1694: }
                   1695: 
                   1696: /************************lvector *******************************/
                   1697: long *lvector(long nl,long nh)
                   1698: {
                   1699:   long *v;
                   1700:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1701:   if (!v) nrerror("allocation failure in ivector");
                   1702:   return v-nl+NR_END;
                   1703: }
                   1704: 
                   1705: /******************free lvector **************************/
                   1706: void free_lvector(long *v, long nl, long nh)
                   1707: {
                   1708:   free((FREE_ARG)(v+nl-NR_END));
                   1709: }
                   1710: 
                   1711: /******************* imatrix *******************************/
                   1712: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1713:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1714: { 
                   1715:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1716:   int **m; 
                   1717:   
                   1718:   /* allocate pointers to rows */ 
                   1719:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1720:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1721:   m += NR_END; 
                   1722:   m -= nrl; 
                   1723:   
                   1724:   
                   1725:   /* allocate rows and set pointers to them */ 
                   1726:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1727:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1728:   m[nrl] += NR_END; 
                   1729:   m[nrl] -= ncl; 
                   1730:   
                   1731:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1732:   
                   1733:   /* return pointer to array of pointers to rows */ 
                   1734:   return m; 
                   1735: } 
                   1736: 
                   1737: /****************** free_imatrix *************************/
                   1738: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1739:       int **m;
                   1740:       long nch,ncl,nrh,nrl; 
                   1741:      /* free an int matrix allocated by imatrix() */ 
                   1742: { 
                   1743:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1744:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1745: } 
                   1746: 
                   1747: /******************* matrix *******************************/
                   1748: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1749: {
                   1750:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1751:   double **m;
                   1752: 
                   1753:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1754:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1755:   m += NR_END;
                   1756:   m -= nrl;
                   1757: 
                   1758:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1759:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1760:   m[nrl] += NR_END;
                   1761:   m[nrl] -= ncl;
                   1762: 
                   1763:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1764:   return m;
1.145     brouard  1765:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1766: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1767: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1768:    */
                   1769: }
                   1770: 
                   1771: /*************************free matrix ************************/
                   1772: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1773: {
                   1774:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1775:   free((FREE_ARG)(m+nrl-NR_END));
                   1776: }
                   1777: 
                   1778: /******************* ma3x *******************************/
                   1779: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1780: {
                   1781:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1782:   double ***m;
                   1783: 
                   1784:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1785:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1786:   m += NR_END;
                   1787:   m -= nrl;
                   1788: 
                   1789:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1790:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1791:   m[nrl] += NR_END;
                   1792:   m[nrl] -= ncl;
                   1793: 
                   1794:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1795: 
                   1796:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1797:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1798:   m[nrl][ncl] += NR_END;
                   1799:   m[nrl][ncl] -= nll;
                   1800:   for (j=ncl+1; j<=nch; j++) 
                   1801:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1802:   
                   1803:   for (i=nrl+1; i<=nrh; i++) {
                   1804:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1805:     for (j=ncl+1; j<=nch; j++) 
                   1806:       m[i][j]=m[i][j-1]+nlay;
                   1807:   }
                   1808:   return m; 
                   1809:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1810:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1811:   */
                   1812: }
                   1813: 
                   1814: /*************************free ma3x ************************/
                   1815: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1816: {
                   1817:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1818:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1819:   free((FREE_ARG)(m+nrl-NR_END));
                   1820: }
                   1821: 
                   1822: /*************** function subdirf ***********/
                   1823: char *subdirf(char fileres[])
                   1824: {
                   1825:   /* Caution optionfilefiname is hidden */
                   1826:   strcpy(tmpout,optionfilefiname);
                   1827:   strcat(tmpout,"/"); /* Add to the right */
                   1828:   strcat(tmpout,fileres);
                   1829:   return tmpout;
                   1830: }
                   1831: 
                   1832: /*************** function subdirf2 ***********/
                   1833: char *subdirf2(char fileres[], char *preop)
                   1834: {
                   1835:   
                   1836:   /* Caution optionfilefiname is hidden */
                   1837:   strcpy(tmpout,optionfilefiname);
                   1838:   strcat(tmpout,"/");
                   1839:   strcat(tmpout,preop);
                   1840:   strcat(tmpout,fileres);
                   1841:   return tmpout;
                   1842: }
                   1843: 
                   1844: /*************** function subdirf3 ***********/
                   1845: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1846: {
                   1847:   
                   1848:   /* Caution optionfilefiname is hidden */
                   1849:   strcpy(tmpout,optionfilefiname);
                   1850:   strcat(tmpout,"/");
                   1851:   strcat(tmpout,preop);
                   1852:   strcat(tmpout,preop2);
                   1853:   strcat(tmpout,fileres);
                   1854:   return tmpout;
                   1855: }
1.213     brouard  1856:  
                   1857: /*************** function subdirfext ***********/
                   1858: char *subdirfext(char fileres[], char *preop, char *postop)
                   1859: {
                   1860:   
                   1861:   strcpy(tmpout,preop);
                   1862:   strcat(tmpout,fileres);
                   1863:   strcat(tmpout,postop);
                   1864:   return tmpout;
                   1865: }
1.126     brouard  1866: 
1.213     brouard  1867: /*************** function subdirfext3 ***********/
                   1868: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1869: {
                   1870:   
                   1871:   /* Caution optionfilefiname is hidden */
                   1872:   strcpy(tmpout,optionfilefiname);
                   1873:   strcat(tmpout,"/");
                   1874:   strcat(tmpout,preop);
                   1875:   strcat(tmpout,fileres);
                   1876:   strcat(tmpout,postop);
                   1877:   return tmpout;
                   1878: }
                   1879:  
1.162     brouard  1880: char *asc_diff_time(long time_sec, char ascdiff[])
                   1881: {
                   1882:   long sec_left, days, hours, minutes;
                   1883:   days = (time_sec) / (60*60*24);
                   1884:   sec_left = (time_sec) % (60*60*24);
                   1885:   hours = (sec_left) / (60*60) ;
                   1886:   sec_left = (sec_left) %(60*60);
                   1887:   minutes = (sec_left) /60;
                   1888:   sec_left = (sec_left) % (60);
                   1889:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1890:   return ascdiff;
                   1891: }
                   1892: 
1.126     brouard  1893: /***************** f1dim *************************/
                   1894: extern int ncom; 
                   1895: extern double *pcom,*xicom;
                   1896: extern double (*nrfunc)(double []); 
                   1897:  
                   1898: double f1dim(double x) 
                   1899: { 
                   1900:   int j; 
                   1901:   double f;
                   1902:   double *xt; 
                   1903:  
                   1904:   xt=vector(1,ncom); 
                   1905:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1906:   f=(*nrfunc)(xt); 
                   1907:   free_vector(xt,1,ncom); 
                   1908:   return f; 
                   1909: } 
                   1910: 
                   1911: /*****************brent *************************/
                   1912: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1913: {
                   1914:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1915:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1916:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1917:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1918:    * returned function value. 
                   1919:   */
1.126     brouard  1920:   int iter; 
                   1921:   double a,b,d,etemp;
1.159     brouard  1922:   double fu=0,fv,fw,fx;
1.164     brouard  1923:   double ftemp=0.;
1.126     brouard  1924:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1925:   double e=0.0; 
                   1926:  
                   1927:   a=(ax < cx ? ax : cx); 
                   1928:   b=(ax > cx ? ax : cx); 
                   1929:   x=w=v=bx; 
                   1930:   fw=fv=fx=(*f)(x); 
                   1931:   for (iter=1;iter<=ITMAX;iter++) { 
                   1932:     xm=0.5*(a+b); 
                   1933:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1934:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1935:     printf(".");fflush(stdout);
                   1936:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1937: #ifdef DEBUGBRENT
1.126     brouard  1938:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1939:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1940:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1941: #endif
                   1942:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1943:       *xmin=x; 
                   1944:       return fx; 
                   1945:     } 
                   1946:     ftemp=fu;
                   1947:     if (fabs(e) > tol1) { 
                   1948:       r=(x-w)*(fx-fv); 
                   1949:       q=(x-v)*(fx-fw); 
                   1950:       p=(x-v)*q-(x-w)*r; 
                   1951:       q=2.0*(q-r); 
                   1952:       if (q > 0.0) p = -p; 
                   1953:       q=fabs(q); 
                   1954:       etemp=e; 
                   1955:       e=d; 
                   1956:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1957:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1958:       else { 
1.224     brouard  1959:                                d=p/q; 
                   1960:                                u=x+d; 
                   1961:                                if (u-a < tol2 || b-u < tol2) 
                   1962:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1963:       } 
                   1964:     } else { 
                   1965:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1966:     } 
                   1967:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1968:     fu=(*f)(u); 
                   1969:     if (fu <= fx) { 
                   1970:       if (u >= x) a=x; else b=x; 
                   1971:       SHFT(v,w,x,u) 
1.183     brouard  1972:       SHFT(fv,fw,fx,fu) 
                   1973:     } else { 
                   1974:       if (u < x) a=u; else b=u; 
                   1975:       if (fu <= fw || w == x) { 
1.224     brouard  1976:                                v=w; 
                   1977:                                w=u; 
                   1978:                                fv=fw; 
                   1979:                                fw=fu; 
1.183     brouard  1980:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1981:                                v=u; 
                   1982:                                fv=fu; 
1.183     brouard  1983:       } 
                   1984:     } 
1.126     brouard  1985:   } 
                   1986:   nrerror("Too many iterations in brent"); 
                   1987:   *xmin=x; 
                   1988:   return fx; 
                   1989: } 
                   1990: 
                   1991: /****************** mnbrak ***********************/
                   1992: 
                   1993: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   1994:            double (*func)(double)) 
1.183     brouard  1995: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   1996: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   1997: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   1998: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   1999:    */
1.126     brouard  2000:   double ulim,u,r,q, dum;
                   2001:   double fu; 
1.187     brouard  2002: 
                   2003:   double scale=10.;
                   2004:   int iterscale=0;
                   2005: 
                   2006:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   2007:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   2008: 
                   2009: 
                   2010:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   2011:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   2012:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   2013:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   2014:   /* } */
                   2015: 
1.126     brouard  2016:   if (*fb > *fa) { 
                   2017:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  2018:     SHFT(dum,*fb,*fa,dum) 
                   2019:   } 
1.126     brouard  2020:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   2021:   *fc=(*func)(*cx); 
1.183     brouard  2022: #ifdef DEBUG
1.224     brouard  2023:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   2024:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  2025: #endif
1.224     brouard  2026:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  2027:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  2028:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  2029:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  2030:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   2031:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   2032:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  2033:       fu=(*func)(u); 
1.163     brouard  2034: #ifdef DEBUG
                   2035:       /* f(x)=A(x-u)**2+f(u) */
                   2036:       double A, fparabu; 
                   2037:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2038:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  2039:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   2040:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  2041:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   2042:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   2043:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   2044:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  2045: #endif 
1.184     brouard  2046: #ifdef MNBRAKORIGINAL
1.183     brouard  2047: #else
1.191     brouard  2048: /*       if (fu > *fc) { */
                   2049: /* #ifdef DEBUG */
                   2050: /*       printf("mnbrak4  fu > fc \n"); */
                   2051: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   2052: /* #endif */
                   2053: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2054: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2055: /*     dum=u; /\* Shifting c and u *\/ */
                   2056: /*     u = *cx; */
                   2057: /*     *cx = dum; */
                   2058: /*     dum = fu; */
                   2059: /*     fu = *fc; */
                   2060: /*     *fc =dum; */
                   2061: /*       } else { /\* end *\/ */
                   2062: /* #ifdef DEBUG */
                   2063: /*       printf("mnbrak3  fu < fc \n"); */
                   2064: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2065: /* #endif */
                   2066: /*     dum=u; /\* Shifting c and u *\/ */
                   2067: /*     u = *cx; */
                   2068: /*     *cx = dum; */
                   2069: /*     dum = fu; */
                   2070: /*     fu = *fc; */
                   2071: /*     *fc =dum; */
                   2072: /*       } */
1.224     brouard  2073: #ifdef DEBUGMNBRAK
                   2074:                 double A, fparabu; 
                   2075:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2076:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2077:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2078:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2079: #endif
1.191     brouard  2080:       dum=u; /* Shifting c and u */
                   2081:       u = *cx;
                   2082:       *cx = dum;
                   2083:       dum = fu;
                   2084:       fu = *fc;
                   2085:       *fc =dum;
1.183     brouard  2086: #endif
1.162     brouard  2087:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2088: #ifdef DEBUG
1.224     brouard  2089:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2090:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2091: #endif
1.126     brouard  2092:       fu=(*func)(u); 
                   2093:       if (fu < *fc) { 
1.183     brouard  2094: #ifdef DEBUG
1.224     brouard  2095:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2096:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2097: #endif
                   2098:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2099:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2100: #ifdef DEBUG
                   2101:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2102: #endif
                   2103:       } 
1.162     brouard  2104:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2105: #ifdef DEBUG
1.224     brouard  2106:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2107:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2108: #endif
1.126     brouard  2109:       u=ulim; 
                   2110:       fu=(*func)(u); 
1.183     brouard  2111:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2112: #ifdef DEBUG
1.224     brouard  2113:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2114:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2115: #endif
1.126     brouard  2116:       u=(*cx)+GOLD*(*cx-*bx); 
                   2117:       fu=(*func)(u); 
1.224     brouard  2118: #ifdef DEBUG
                   2119:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2120:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2121: #endif
1.183     brouard  2122:     } /* end tests */
1.126     brouard  2123:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2124:     SHFT(*fa,*fb,*fc,fu) 
                   2125: #ifdef DEBUG
1.224     brouard  2126:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2127:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2128: #endif
                   2129:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2130: } 
                   2131: 
                   2132: /*************** linmin ************************/
1.162     brouard  2133: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2134: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2135: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2136: the value of func at the returned location p . This is actually all accomplished by calling the
                   2137: routines mnbrak and brent .*/
1.126     brouard  2138: int ncom; 
                   2139: double *pcom,*xicom;
                   2140: double (*nrfunc)(double []); 
                   2141:  
1.224     brouard  2142: #ifdef LINMINORIGINAL
1.126     brouard  2143: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2144: #else
                   2145: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2146: #endif
1.126     brouard  2147: { 
                   2148:   double brent(double ax, double bx, double cx, 
                   2149:               double (*f)(double), double tol, double *xmin); 
                   2150:   double f1dim(double x); 
                   2151:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2152:              double *fc, double (*func)(double)); 
                   2153:   int j; 
                   2154:   double xx,xmin,bx,ax; 
                   2155:   double fx,fb,fa;
1.187     brouard  2156: 
1.203     brouard  2157: #ifdef LINMINORIGINAL
                   2158: #else
                   2159:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2160: #endif
                   2161:   
1.126     brouard  2162:   ncom=n; 
                   2163:   pcom=vector(1,n); 
                   2164:   xicom=vector(1,n); 
                   2165:   nrfunc=func; 
                   2166:   for (j=1;j<=n;j++) { 
                   2167:     pcom[j]=p[j]; 
1.202     brouard  2168:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2169:   } 
1.187     brouard  2170: 
1.203     brouard  2171: #ifdef LINMINORIGINAL
                   2172:   xx=1.;
                   2173: #else
                   2174:   axs=0.0;
                   2175:   xxs=1.;
                   2176:   do{
                   2177:     xx= xxs;
                   2178: #endif
1.187     brouard  2179:     ax=0.;
                   2180:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2181:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2182:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2183:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2184:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2185:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2186:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2187: #ifdef LINMINORIGINAL
                   2188: #else
                   2189:     if (fx != fx){
1.224     brouard  2190:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2191:                        printf("|");
                   2192:                        fprintf(ficlog,"|");
1.203     brouard  2193: #ifdef DEBUGLINMIN
1.224     brouard  2194:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2195: #endif
                   2196:     }
1.224     brouard  2197:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2198: #endif
                   2199:   
1.191     brouard  2200: #ifdef DEBUGLINMIN
                   2201:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2202:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2203: #endif
1.224     brouard  2204: #ifdef LINMINORIGINAL
                   2205: #else
                   2206:        if(fb == fx){ /* Flat function in the direction */
                   2207:                xmin=xx;
                   2208:     *flat=1;
                   2209:        }else{
                   2210:     *flat=0;
                   2211: #endif
                   2212:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2213:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2214:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2215:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2216:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2217:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2218: #ifdef DEBUG
1.224     brouard  2219:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2220:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2221: #endif
                   2222: #ifdef LINMINORIGINAL
                   2223: #else
                   2224:                        }
1.126     brouard  2225: #endif
1.191     brouard  2226: #ifdef DEBUGLINMIN
                   2227:   printf("linmin end ");
1.202     brouard  2228:   fprintf(ficlog,"linmin end ");
1.191     brouard  2229: #endif
1.126     brouard  2230:   for (j=1;j<=n;j++) { 
1.203     brouard  2231: #ifdef LINMINORIGINAL
                   2232:     xi[j] *= xmin; 
                   2233: #else
                   2234: #ifdef DEBUGLINMIN
                   2235:     if(xxs <1.0)
                   2236:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2237: #endif
                   2238:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2239: #ifdef DEBUGLINMIN
                   2240:     if(xxs <1.0)
                   2241:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2242: #endif
                   2243: #endif
1.187     brouard  2244:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2245:   } 
1.191     brouard  2246: #ifdef DEBUGLINMIN
1.203     brouard  2247:   printf("\n");
1.191     brouard  2248:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2249:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2250:   for (j=1;j<=n;j++) { 
1.202     brouard  2251:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2252:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2253:     if(j % ncovmodel == 0){
1.191     brouard  2254:       printf("\n");
1.202     brouard  2255:       fprintf(ficlog,"\n");
                   2256:     }
1.191     brouard  2257:   }
1.203     brouard  2258: #else
1.191     brouard  2259: #endif
1.126     brouard  2260:   free_vector(xicom,1,n); 
                   2261:   free_vector(pcom,1,n); 
                   2262: } 
                   2263: 
                   2264: 
                   2265: /*************** powell ************************/
1.162     brouard  2266: /*
                   2267: Minimization of a function func of n variables. Input consists of an initial starting point
                   2268: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2269: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2270: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2271: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2272: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2273:  */
1.224     brouard  2274: #ifdef LINMINORIGINAL
                   2275: #else
                   2276:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2277:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2278: #endif
1.126     brouard  2279: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2280:            double (*func)(double [])) 
                   2281: { 
1.224     brouard  2282: #ifdef LINMINORIGINAL
                   2283:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2284:              double (*func)(double [])); 
1.224     brouard  2285: #else 
1.241     brouard  2286:  void linmin(double p[], double xi[], int n, double *fret,
                   2287:             double (*func)(double []),int *flat); 
1.224     brouard  2288: #endif
1.239     brouard  2289:  int i,ibig,j,jk,k; 
1.126     brouard  2290:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2291:   double directest;
1.126     brouard  2292:   double fp,fptt;
                   2293:   double *xits;
                   2294:   int niterf, itmp;
1.224     brouard  2295: #ifdef LINMINORIGINAL
                   2296: #else
                   2297: 
                   2298:   flatdir=ivector(1,n); 
                   2299:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2300: #endif
1.126     brouard  2301: 
                   2302:   pt=vector(1,n); 
                   2303:   ptt=vector(1,n); 
                   2304:   xit=vector(1,n); 
                   2305:   xits=vector(1,n); 
                   2306:   *fret=(*func)(p); 
                   2307:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2308:   rcurr_time = time(NULL);  
1.126     brouard  2309:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2310:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2311:     ibig=0; 
                   2312:     del=0.0; 
1.157     brouard  2313:     rlast_time=rcurr_time;
                   2314:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2315:     rcurr_time = time(NULL);  
                   2316:     curr_time = *localtime(&rcurr_time);
                   2317:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2318:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2319: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2320:     for (i=1;i<=n;i++) {
1.126     brouard  2321:       fprintf(ficrespow," %.12lf", p[i]);
                   2322:     }
1.239     brouard  2323:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2324:     printf("\n#model=  1      +     age ");
                   2325:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2326:     if(nagesqr==1){
1.241     brouard  2327:        printf("  + age*age  ");
                   2328:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2329:     }
                   2330:     for(j=1;j <=ncovmodel-2;j++){
                   2331:       if(Typevar[j]==0) {
                   2332:        printf("  +      V%d  ",Tvar[j]);
                   2333:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2334:       }else if(Typevar[j]==1) {
                   2335:        printf("  +    V%d*age ",Tvar[j]);
                   2336:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2337:       }else if(Typevar[j]==2) {
                   2338:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2339:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2340:       }
                   2341:     }
1.126     brouard  2342:     printf("\n");
1.239     brouard  2343: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2344: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2345:     fprintf(ficlog,"\n");
1.239     brouard  2346:     for(i=1,jk=1; i <=nlstate; i++){
                   2347:       for(k=1; k <=(nlstate+ndeath); k++){
                   2348:        if (k != i) {
                   2349:          printf("%d%d ",i,k);
                   2350:          fprintf(ficlog,"%d%d ",i,k);
                   2351:          for(j=1; j <=ncovmodel; j++){
                   2352:            printf("%12.7f ",p[jk]);
                   2353:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2354:            jk++; 
                   2355:          }
                   2356:          printf("\n");
                   2357:          fprintf(ficlog,"\n");
                   2358:        }
                   2359:       }
                   2360:     }
1.241     brouard  2361:     if(*iter <=3 && *iter >1){
1.157     brouard  2362:       tml = *localtime(&rcurr_time);
                   2363:       strcpy(strcurr,asctime(&tml));
                   2364:       rforecast_time=rcurr_time; 
1.126     brouard  2365:       itmp = strlen(strcurr);
                   2366:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2367:        strcurr[itmp-1]='\0';
1.162     brouard  2368:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2369:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2370:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2371:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2372:        forecast_time = *localtime(&rforecast_time);
                   2373:        strcpy(strfor,asctime(&forecast_time));
                   2374:        itmp = strlen(strfor);
                   2375:        if(strfor[itmp-1]=='\n')
                   2376:          strfor[itmp-1]='\0';
                   2377:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2378:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2379:       }
                   2380:     }
1.187     brouard  2381:     for (i=1;i<=n;i++) { /* For each direction i */
                   2382:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2383:       fptt=(*fret); 
                   2384: #ifdef DEBUG
1.203     brouard  2385:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2386:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2387: #endif
1.203     brouard  2388:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2389:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2390: #ifdef LINMINORIGINAL
1.188     brouard  2391:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2392: #else
                   2393:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2394:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2395: #endif
                   2396:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2397:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2398:                                /* because that direction will be replaced unless the gain del is small */
                   2399:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2400:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2401:                                /* with the new direction. */
                   2402:                                del=fabs(fptt-(*fret)); 
                   2403:                                ibig=i; 
1.126     brouard  2404:       } 
                   2405: #ifdef DEBUG
                   2406:       printf("%d %.12e",i,(*fret));
                   2407:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2408:       for (j=1;j<=n;j++) {
1.224     brouard  2409:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2410:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2411:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2412:       }
                   2413:       for(j=1;j<=n;j++) {
1.225     brouard  2414:                                printf(" p(%d)=%.12e",j,p[j]);
                   2415:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2416:       }
                   2417:       printf("\n");
                   2418:       fprintf(ficlog,"\n");
                   2419: #endif
1.187     brouard  2420:     } /* end loop on each direction i */
                   2421:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2422:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2423:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2424:       for(j=1;j<=n;j++) {
1.302     brouard  2425:        if(flatdir[j] >0){
                   2426:          printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2427:          fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2428:        }
                   2429:        /* printf("\n"); */
                   2430:        /* fprintf(ficlog,"\n"); */
                   2431:       }
1.243     brouard  2432:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2433:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2434:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2435:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2436:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2437:       /* decreased of more than 3.84  */
                   2438:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2439:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2440:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2441:                        
1.188     brouard  2442:       /* Starting the program with initial values given by a former maximization will simply change */
                   2443:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2444:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2445:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2446: #ifdef DEBUG
                   2447:       int k[2],l;
                   2448:       k[0]=1;
                   2449:       k[1]=-1;
                   2450:       printf("Max: %.12e",(*func)(p));
                   2451:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2452:       for (j=1;j<=n;j++) {
                   2453:        printf(" %.12e",p[j]);
                   2454:        fprintf(ficlog," %.12e",p[j]);
                   2455:       }
                   2456:       printf("\n");
                   2457:       fprintf(ficlog,"\n");
                   2458:       for(l=0;l<=1;l++) {
                   2459:        for (j=1;j<=n;j++) {
                   2460:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2461:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2462:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2463:        }
                   2464:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2465:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2466:       }
                   2467: #endif
                   2468: 
1.224     brouard  2469: #ifdef LINMINORIGINAL
                   2470: #else
                   2471:       free_ivector(flatdir,1,n); 
                   2472: #endif
1.126     brouard  2473:       free_vector(xit,1,n); 
                   2474:       free_vector(xits,1,n); 
                   2475:       free_vector(ptt,1,n); 
                   2476:       free_vector(pt,1,n); 
                   2477:       return; 
1.192     brouard  2478:     } /* enough precision */ 
1.240     brouard  2479:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2480:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2481:       ptt[j]=2.0*p[j]-pt[j]; 
                   2482:       xit[j]=p[j]-pt[j]; 
                   2483:       pt[j]=p[j]; 
                   2484:     } 
1.181     brouard  2485:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2486: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2487:                if (*iter <=4) {
1.225     brouard  2488: #else
                   2489: #endif
1.224     brouard  2490: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2491: #else
1.161     brouard  2492:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2493: #endif
1.162     brouard  2494:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2495:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2496:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2497:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2498:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2499:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2500:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2501:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2502:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2503:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2504:       /* mu² and del² are equal when f3=f1 */
                   2505:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2506:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2507:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2508:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2509: #ifdef NRCORIGINAL
                   2510:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2511: #else
                   2512:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2513:       t= t- del*SQR(fp-fptt);
1.183     brouard  2514: #endif
1.202     brouard  2515:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2516: #ifdef DEBUG
1.181     brouard  2517:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2518:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2519:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2520:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2521:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2522:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2523:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2524:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2525: #endif
1.183     brouard  2526: #ifdef POWELLORIGINAL
                   2527:       if (t < 0.0) { /* Then we use it for new direction */
                   2528: #else
1.182     brouard  2529:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2530:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2531:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2532:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2533:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2534:       } 
1.181     brouard  2535:       if (directest < 0.0) { /* Then we use it for new direction */
                   2536: #endif
1.191     brouard  2537: #ifdef DEBUGLINMIN
1.234     brouard  2538:        printf("Before linmin in direction P%d-P0\n",n);
                   2539:        for (j=1;j<=n;j++) {
                   2540:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2541:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2542:          if(j % ncovmodel == 0){
                   2543:            printf("\n");
                   2544:            fprintf(ficlog,"\n");
                   2545:          }
                   2546:        }
1.224     brouard  2547: #endif
                   2548: #ifdef LINMINORIGINAL
1.234     brouard  2549:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2550: #else
1.234     brouard  2551:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2552:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2553: #endif
1.234     brouard  2554:        
1.191     brouard  2555: #ifdef DEBUGLINMIN
1.234     brouard  2556:        for (j=1;j<=n;j++) { 
                   2557:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2558:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2559:          if(j % ncovmodel == 0){
                   2560:            printf("\n");
                   2561:            fprintf(ficlog,"\n");
                   2562:          }
                   2563:        }
1.224     brouard  2564: #endif
1.234     brouard  2565:        for (j=1;j<=n;j++) { 
                   2566:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2567:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2568:        }
1.224     brouard  2569: #ifdef LINMINORIGINAL
                   2570: #else
1.234     brouard  2571:        for (j=1, flatd=0;j<=n;j++) {
                   2572:          if(flatdir[j]>0)
                   2573:            flatd++;
                   2574:        }
                   2575:        if(flatd >0){
1.255     brouard  2576:          printf("%d flat directions: ",flatd);
                   2577:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2578:          for (j=1;j<=n;j++) { 
                   2579:            if(flatdir[j]>0){
                   2580:              printf("%d ",j);
                   2581:              fprintf(ficlog,"%d ",j);
                   2582:            }
                   2583:          }
                   2584:          printf("\n");
                   2585:          fprintf(ficlog,"\n");
                   2586:        }
1.191     brouard  2587: #endif
1.234     brouard  2588:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2589:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2590:        
1.126     brouard  2591: #ifdef DEBUG
1.234     brouard  2592:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2593:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2594:        for(j=1;j<=n;j++){
                   2595:          printf(" %lf",xit[j]);
                   2596:          fprintf(ficlog," %lf",xit[j]);
                   2597:        }
                   2598:        printf("\n");
                   2599:        fprintf(ficlog,"\n");
1.126     brouard  2600: #endif
1.192     brouard  2601:       } /* end of t or directest negative */
1.224     brouard  2602: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2603: #else
1.234     brouard  2604:       } /* end if (fptt < fp)  */
1.192     brouard  2605: #endif
1.225     brouard  2606: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2607:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2608: #else
1.224     brouard  2609: #endif
1.234     brouard  2610:                } /* loop iteration */ 
1.126     brouard  2611: } 
1.234     brouard  2612:   
1.126     brouard  2613: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2614:   
1.235     brouard  2615:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2616:   {
1.279     brouard  2617:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2618:      *   (and selected quantitative values in nres)
                   2619:      *  by left multiplying the unit
                   2620:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2621:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2622:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2623:      * or prevalence in state 1, prevalence in state 2, 0
                   2624:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2625:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2626:      * Output is prlim.
                   2627:      * Initial matrix pimij 
                   2628:      */
1.206     brouard  2629:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2630:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2631:   /*  0,                   0                  , 1} */
                   2632:   /*
                   2633:    * and after some iteration: */
                   2634:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2635:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2636:   /*  0,                   0                  , 1} */
                   2637:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2638:   /* {0.51571254859325999, 0.4842874514067399, */
                   2639:   /*  0.51326036147820708, 0.48673963852179264} */
                   2640:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2641:     
1.126     brouard  2642:   int i, ii,j,k;
1.209     brouard  2643:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2644:   /* double **matprod2(); */ /* test */
1.218     brouard  2645:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2646:   double **newm;
1.209     brouard  2647:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2648:   int ncvloop=0;
1.288     brouard  2649:   int first=0;
1.169     brouard  2650:   
1.209     brouard  2651:   min=vector(1,nlstate);
                   2652:   max=vector(1,nlstate);
                   2653:   meandiff=vector(1,nlstate);
                   2654: 
1.218     brouard  2655:        /* Starting with matrix unity */
1.126     brouard  2656:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2657:     for (j=1;j<=nlstate+ndeath;j++){
                   2658:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2659:     }
1.169     brouard  2660:   
                   2661:   cov[1]=1.;
                   2662:   
                   2663:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2664:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2665:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2666:     ncvloop++;
1.126     brouard  2667:     newm=savm;
                   2668:     /* Covariates have to be included here again */
1.138     brouard  2669:     cov[2]=agefin;
1.187     brouard  2670:     if(nagesqr==1)
                   2671:       cov[3]= agefin*agefin;;
1.234     brouard  2672:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2673:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2674:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2675:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2676:     }
                   2677:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2678:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2679:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2680:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2681:     }
1.237     brouard  2682:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2683:       if(Dummy[Tvar[Tage[k]]]){
                   2684:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2685:       } else{
1.235     brouard  2686:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2687:       }
1.235     brouard  2688:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2689:     }
1.237     brouard  2690:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2691:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2692:       if(Dummy[Tvard[k][1]==0]){
                   2693:        if(Dummy[Tvard[k][2]==0]){
                   2694:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2695:        }else{
                   2696:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2697:        }
                   2698:       }else{
                   2699:        if(Dummy[Tvard[k][2]==0]){
                   2700:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2701:        }else{
                   2702:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2703:        }
                   2704:       }
1.234     brouard  2705:     }
1.138     brouard  2706:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2707:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2708:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2709:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2710:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2711:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2712:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2713:     
1.126     brouard  2714:     savm=oldm;
                   2715:     oldm=newm;
1.209     brouard  2716: 
                   2717:     for(j=1; j<=nlstate; j++){
                   2718:       max[j]=0.;
                   2719:       min[j]=1.;
                   2720:     }
                   2721:     for(i=1;i<=nlstate;i++){
                   2722:       sumnew=0;
                   2723:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2724:       for(j=1; j<=nlstate; j++){ 
                   2725:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2726:        max[j]=FMAX(max[j],prlim[i][j]);
                   2727:        min[j]=FMIN(min[j],prlim[i][j]);
                   2728:       }
                   2729:     }
                   2730: 
1.126     brouard  2731:     maxmax=0.;
1.209     brouard  2732:     for(j=1; j<=nlstate; j++){
                   2733:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2734:       maxmax=FMAX(maxmax,meandiff[j]);
                   2735:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2736:     } /* j loop */
1.203     brouard  2737:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2738:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2739:     if(maxmax < ftolpl){
1.209     brouard  2740:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2741:       free_vector(min,1,nlstate);
                   2742:       free_vector(max,1,nlstate);
                   2743:       free_vector(meandiff,1,nlstate);
1.126     brouard  2744:       return prlim;
                   2745:     }
1.288     brouard  2746:   } /* agefin loop */
1.208     brouard  2747:     /* After some age loop it doesn't converge */
1.288     brouard  2748:   if(!first){
                   2749:     first=1;
                   2750:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2751:   }
                   2752:   fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2753: 
1.209     brouard  2754:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2755:   free_vector(min,1,nlstate);
                   2756:   free_vector(max,1,nlstate);
                   2757:   free_vector(meandiff,1,nlstate);
1.208     brouard  2758:   
1.169     brouard  2759:   return prlim; /* should not reach here */
1.126     brouard  2760: }
                   2761: 
1.217     brouard  2762: 
                   2763:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2764: 
1.218     brouard  2765:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2766:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2767:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2768: {
1.264     brouard  2769:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2770:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2771:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2772:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2773:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2774:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2775:   /* Initial matrix pimij */
                   2776:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2777:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2778:   /*  0,                   0                  , 1} */
                   2779:   /*
                   2780:    * and after some iteration: */
                   2781:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2782:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2783:   /*  0,                   0                  , 1} */
                   2784:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2785:   /* {0.51571254859325999, 0.4842874514067399, */
                   2786:   /*  0.51326036147820708, 0.48673963852179264} */
                   2787:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2788: 
                   2789:   int i, ii,j,k;
1.247     brouard  2790:   int first=0;
1.217     brouard  2791:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2792:   /* double **matprod2(); */ /* test */
                   2793:   double **out, cov[NCOVMAX+1], **bmij();
                   2794:   double **newm;
1.218     brouard  2795:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2796:   double        **oldm, **savm;  /* for use */
                   2797: 
1.217     brouard  2798:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2799:   int ncvloop=0;
                   2800:   
                   2801:   min=vector(1,nlstate);
                   2802:   max=vector(1,nlstate);
                   2803:   meandiff=vector(1,nlstate);
                   2804: 
1.266     brouard  2805:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2806:   oldm=oldms; savm=savms;
                   2807:   
                   2808:   /* Starting with matrix unity */
                   2809:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2810:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2811:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2812:     }
                   2813:   
                   2814:   cov[1]=1.;
                   2815:   
                   2816:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2817:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2818:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2819:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2820:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2821:     ncvloop++;
1.218     brouard  2822:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2823:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2824:     /* Covariates have to be included here again */
                   2825:     cov[2]=agefin;
                   2826:     if(nagesqr==1)
                   2827:       cov[3]= agefin*agefin;;
1.242     brouard  2828:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2829:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2830:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2831:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2832:     }
                   2833:     /* for (k=1; k<=cptcovn;k++) { */
                   2834:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2835:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2836:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2837:     /* } */
                   2838:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2839:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2840:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2841:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2842:     }
                   2843:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2844:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2845:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2846:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2847:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2848:       if(Dummy[Tvar[Tage[k]]]){
                   2849:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2850:       } else{
                   2851:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2852:       }
                   2853:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2854:     }
                   2855:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2856:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2857:       if(Dummy[Tvard[k][1]==0]){
                   2858:        if(Dummy[Tvard[k][2]==0]){
                   2859:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2860:        }else{
                   2861:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2862:        }
                   2863:       }else{
                   2864:        if(Dummy[Tvard[k][2]==0]){
                   2865:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2866:        }else{
                   2867:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2868:        }
                   2869:       }
1.217     brouard  2870:     }
                   2871:     
                   2872:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2873:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2874:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2875:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2876:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2877:                /* ij should be linked to the correct index of cov */
                   2878:                /* age and covariate values ij are in 'cov', but we need to pass
                   2879:                 * ij for the observed prevalence at age and status and covariate
                   2880:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2881:                 */
                   2882:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2883:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2884:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2885:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2886:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2887:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2888:     /*         printf("%d newm= ",i); */
                   2889:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2890:     /*           printf("%f ",newm[i][j]); */
                   2891:     /*         } */
                   2892:     /*         printf("oldm * "); */
                   2893:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2894:     /*           printf("%f ",oldm[i][j]); */
                   2895:     /*         } */
1.268     brouard  2896:     /*         printf(" bmmij "); */
1.266     brouard  2897:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2898:     /*           printf("%f ",pmmij[i][j]); */
                   2899:     /*         } */
                   2900:     /*         printf("\n"); */
                   2901:     /*   } */
                   2902:     /* } */
1.217     brouard  2903:     savm=oldm;
                   2904:     oldm=newm;
1.266     brouard  2905: 
1.217     brouard  2906:     for(j=1; j<=nlstate; j++){
                   2907:       max[j]=0.;
                   2908:       min[j]=1.;
                   2909:     }
                   2910:     for(j=1; j<=nlstate; j++){ 
                   2911:       for(i=1;i<=nlstate;i++){
1.234     brouard  2912:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2913:        bprlim[i][j]= newm[i][j];
                   2914:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2915:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2916:       }
                   2917:     }
1.218     brouard  2918:                
1.217     brouard  2919:     maxmax=0.;
                   2920:     for(i=1; i<=nlstate; i++){
                   2921:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2922:       maxmax=FMAX(maxmax,meandiff[i]);
                   2923:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2924:     } /* i loop */
1.217     brouard  2925:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2926:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2927:     if(maxmax < ftolpl){
1.220     brouard  2928:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2929:       free_vector(min,1,nlstate);
                   2930:       free_vector(max,1,nlstate);
                   2931:       free_vector(meandiff,1,nlstate);
                   2932:       return bprlim;
                   2933:     }
1.288     brouard  2934:   } /* agefin loop */
1.217     brouard  2935:     /* After some age loop it doesn't converge */
1.288     brouard  2936:   if(!first){
1.247     brouard  2937:     first=1;
                   2938:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2939: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2940:   }
                   2941:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2942: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2943:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2944:   free_vector(min,1,nlstate);
                   2945:   free_vector(max,1,nlstate);
                   2946:   free_vector(meandiff,1,nlstate);
                   2947:   
                   2948:   return bprlim; /* should not reach here */
                   2949: }
                   2950: 
1.126     brouard  2951: /*************** transition probabilities ***************/ 
                   2952: 
                   2953: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2954: {
1.138     brouard  2955:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2956:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2957:      model to the ncovmodel covariates (including constant and age).
                   2958:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2959:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2960:      ncth covariate in the global vector x is given by the formula:
                   2961:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2962:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2963:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2964:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2965:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2966:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2967:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2968:   */
                   2969:   double s1, lnpijopii;
1.126     brouard  2970:   /*double t34;*/
1.164     brouard  2971:   int i,j, nc, ii, jj;
1.126     brouard  2972: 
1.223     brouard  2973:   for(i=1; i<= nlstate; i++){
                   2974:     for(j=1; j<i;j++){
                   2975:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2976:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2977:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2978:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2979:       }
                   2980:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2981:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2982:     }
                   2983:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2984:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2985:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   2986:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   2987:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   2988:       }
                   2989:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2990:     }
                   2991:   }
1.218     brouard  2992:   
1.223     brouard  2993:   for(i=1; i<= nlstate; i++){
                   2994:     s1=0;
                   2995:     for(j=1; j<i; j++){
                   2996:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   2997:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   2998:     }
                   2999:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3000:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3001:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3002:     }
                   3003:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3004:     ps[i][i]=1./(s1+1.);
                   3005:     /* Computing other pijs */
                   3006:     for(j=1; j<i; j++)
                   3007:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3008:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3009:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3010:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3011:   } /* end i */
1.218     brouard  3012:   
1.223     brouard  3013:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3014:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3015:       ps[ii][jj]=0;
                   3016:       ps[ii][ii]=1;
                   3017:     }
                   3018:   }
1.294     brouard  3019: 
                   3020: 
1.223     brouard  3021:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3022:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3023:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3024:   /*   } */
                   3025:   /*   printf("\n "); */
                   3026:   /* } */
                   3027:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3028:   /*
                   3029:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  3030:                goto end;*/
1.266     brouard  3031:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  3032: }
                   3033: 
1.218     brouard  3034: /*************** backward transition probabilities ***************/ 
                   3035: 
                   3036:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3037: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3038:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   3039: {
1.302     brouard  3040:   /* Computes the backward probability at age agefin, cov[2], and covariate combination 'ij'. In fact cov is already filled and x too.
1.266     brouard  3041:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  3042:    */
1.218     brouard  3043:   int i, ii, j,k;
1.222     brouard  3044:   
                   3045:   double **out, **pmij();
                   3046:   double sumnew=0.;
1.218     brouard  3047:   double agefin;
1.292     brouard  3048:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  3049:   double **dnewm, **dsavm, **doldm;
                   3050:   double **bbmij;
                   3051:   
1.218     brouard  3052:   doldm=ddoldms; /* global pointers */
1.222     brouard  3053:   dnewm=ddnewms;
                   3054:   dsavm=ddsavms;
                   3055:   
                   3056:   agefin=cov[2];
1.268     brouard  3057:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3058:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3059:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3060:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3061: 
                   3062:   /* P_x */
1.266     brouard  3063:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3064:   /* outputs pmmij which is a stochastic matrix in row */
                   3065: 
                   3066:   /* Diag(w_x) */
1.292     brouard  3067:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3068:   sumnew=0.;
1.269     brouard  3069:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3070:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.297     brouard  3071:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]); */
1.268     brouard  3072:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3073:   }
                   3074:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3075:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3076:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3077:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3078:     }
                   3079:   }else{
                   3080:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3081:       for (j=1;j<=nlstate+ndeath;j++)
                   3082:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3083:     }
                   3084:     /* if(sumnew <0.9){ */
                   3085:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3086:     /* } */
                   3087:   }
                   3088:   k3=0.0;  /* We put the last diagonal to 0 */
                   3089:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3090:       doldm[ii][ii]= k3;
                   3091:   }
                   3092:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3093:   
1.292     brouard  3094:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
                   3095:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3096: 
1.292     brouard  3097:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3098:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3099:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3100:     sumnew=0.;
1.222     brouard  3101:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3102:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3103:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3104:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3105:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3106:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3107:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3108:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3109:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3110:        /* }else */
1.268     brouard  3111:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3112:     } /*End ii */
                   3113:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3114: 
1.292     brouard  3115:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3116:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3117:   /* end bmij */
1.266     brouard  3118:   return ps; /*pointer is unchanged */
1.218     brouard  3119: }
1.217     brouard  3120: /*************** transition probabilities ***************/ 
                   3121: 
1.218     brouard  3122: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3123: {
                   3124:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3125:      computes the probability to be observed in state j being in state i by appying the
                   3126:      model to the ncovmodel covariates (including constant and age).
                   3127:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3128:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3129:      ncth covariate in the global vector x is given by the formula:
                   3130:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3131:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3132:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3133:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3134:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3135:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3136:   */
                   3137:   double s1, lnpijopii;
                   3138:   /*double t34;*/
                   3139:   int i,j, nc, ii, jj;
                   3140: 
1.234     brouard  3141:   for(i=1; i<= nlstate; i++){
                   3142:     for(j=1; j<i;j++){
                   3143:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3144:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3145:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3146:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3147:       }
                   3148:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3149:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3150:     }
                   3151:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3152:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3153:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3154:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3155:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3156:       }
                   3157:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3158:     }
                   3159:   }
                   3160:   
                   3161:   for(i=1; i<= nlstate; i++){
                   3162:     s1=0;
                   3163:     for(j=1; j<i; j++){
                   3164:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3165:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3166:     }
                   3167:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3168:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3169:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3170:     }
                   3171:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3172:     ps[i][i]=1./(s1+1.);
                   3173:     /* Computing other pijs */
                   3174:     for(j=1; j<i; j++)
                   3175:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3176:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3177:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3178:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3179:   } /* end i */
                   3180:   
                   3181:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3182:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3183:       ps[ii][jj]=0;
                   3184:       ps[ii][ii]=1;
                   3185:     }
                   3186:   }
1.296     brouard  3187:   /* Added for prevbcast */ /* Transposed matrix too */
1.234     brouard  3188:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3189:     s1=0.;
                   3190:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3191:       s1+=ps[ii][jj];
                   3192:     }
                   3193:     for(ii=1; ii<= nlstate; ii++){
                   3194:       ps[ii][jj]=ps[ii][jj]/s1;
                   3195:     }
                   3196:   }
                   3197:   /* Transposition */
                   3198:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3199:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3200:       s1=ps[ii][jj];
                   3201:       ps[ii][jj]=ps[jj][ii];
                   3202:       ps[jj][ii]=s1;
                   3203:     }
                   3204:   }
                   3205:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3206:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3207:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3208:   /*   } */
                   3209:   /*   printf("\n "); */
                   3210:   /* } */
                   3211:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3212:   /*
                   3213:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3214:     goto end;*/
                   3215:   return ps;
1.217     brouard  3216: }
                   3217: 
                   3218: 
1.126     brouard  3219: /**************** Product of 2 matrices ******************/
                   3220: 
1.145     brouard  3221: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3222: {
                   3223:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3224:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3225:   /* in, b, out are matrice of pointers which should have been initialized 
                   3226:      before: only the contents of out is modified. The function returns
                   3227:      a pointer to pointers identical to out */
1.145     brouard  3228:   int i, j, k;
1.126     brouard  3229:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3230:     for(k=ncolol; k<=ncoloh; k++){
                   3231:       out[i][k]=0.;
                   3232:       for(j=ncl; j<=nch; j++)
                   3233:        out[i][k] +=in[i][j]*b[j][k];
                   3234:     }
1.126     brouard  3235:   return out;
                   3236: }
                   3237: 
                   3238: 
                   3239: /************* Higher Matrix Product ***************/
                   3240: 
1.235     brouard  3241: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3242: {
1.218     brouard  3243:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3244:      'nhstepm*hstepm*stepm' months (i.e. until
                   3245:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3246:      nhstepm*hstepm matrices. 
                   3247:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3248:      (typically every 2 years instead of every month which is too big 
                   3249:      for the memory).
                   3250:      Model is determined by parameters x and covariates have to be 
                   3251:      included manually here. 
                   3252: 
                   3253:      */
                   3254: 
                   3255:   int i, j, d, h, k;
1.131     brouard  3256:   double **out, cov[NCOVMAX+1];
1.126     brouard  3257:   double **newm;
1.187     brouard  3258:   double agexact;
1.214     brouard  3259:   double agebegin, ageend;
1.126     brouard  3260: 
                   3261:   /* Hstepm could be zero and should return the unit matrix */
                   3262:   for (i=1;i<=nlstate+ndeath;i++)
                   3263:     for (j=1;j<=nlstate+ndeath;j++){
                   3264:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3265:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3266:     }
                   3267:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3268:   for(h=1; h <=nhstepm; h++){
                   3269:     for(d=1; d <=hstepm; d++){
                   3270:       newm=savm;
                   3271:       /* Covariates have to be included here again */
                   3272:       cov[1]=1.;
1.214     brouard  3273:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3274:       cov[2]=agexact;
                   3275:       if(nagesqr==1)
1.227     brouard  3276:        cov[3]= agexact*agexact;
1.235     brouard  3277:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3278:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3279:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3280:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3281:       }
                   3282:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3283:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3284:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3285:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3286:       }
                   3287:       for (k=1; k<=cptcovage;k++){
                   3288:        if(Dummy[Tvar[Tage[k]]]){
                   3289:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3290:        } else{
                   3291:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3292:        }
                   3293:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3294:       }
                   3295:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3296:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3297:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3298:       }
                   3299:       /* for (k=1; k<=cptcovn;k++)  */
                   3300:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3301:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3302:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3303:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3304:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3305:       
                   3306:       
1.126     brouard  3307:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3308:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3309:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3310:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3311:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3312:       /* if((int)age == 70){ */
                   3313:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3314:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3315:       /*         printf("%d pmmij ",i); */
                   3316:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3317:       /*           printf("%f ",pmmij[i][j]); */
                   3318:       /*         } */
                   3319:       /*         printf(" oldm "); */
                   3320:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3321:       /*           printf("%f ",oldm[i][j]); */
                   3322:       /*         } */
                   3323:       /*         printf("\n"); */
                   3324:       /*       } */
                   3325:       /* } */
1.126     brouard  3326:       savm=oldm;
                   3327:       oldm=newm;
                   3328:     }
                   3329:     for(i=1; i<=nlstate+ndeath; i++)
                   3330:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3331:        po[i][j][h]=newm[i][j];
                   3332:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3333:       }
1.128     brouard  3334:     /*printf("h=%d ",h);*/
1.126     brouard  3335:   } /* end h */
1.267     brouard  3336:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3337:   return po;
                   3338: }
                   3339: 
1.217     brouard  3340: /************* Higher Back Matrix Product ***************/
1.218     brouard  3341: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3342: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3343: {
1.266     brouard  3344:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3345:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3346:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3347:      nhstepm*hstepm matrices.
                   3348:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3349:      (typically every 2 years instead of every month which is too big
1.217     brouard  3350:      for the memory).
1.218     brouard  3351:      Model is determined by parameters x and covariates have to be
1.266     brouard  3352:      included manually here. Then we use a call to bmij(x and cov)
                   3353:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3354:   */
1.217     brouard  3355: 
                   3356:   int i, j, d, h, k;
1.266     brouard  3357:   double **out, cov[NCOVMAX+1], **bmij();
                   3358:   double **newm, ***newmm;
1.217     brouard  3359:   double agexact;
                   3360:   double agebegin, ageend;
1.222     brouard  3361:   double **oldm, **savm;
1.217     brouard  3362: 
1.266     brouard  3363:   newmm=po; /* To be saved */
                   3364:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3365:   /* Hstepm could be zero and should return the unit matrix */
                   3366:   for (i=1;i<=nlstate+ndeath;i++)
                   3367:     for (j=1;j<=nlstate+ndeath;j++){
                   3368:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3369:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3370:     }
                   3371:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3372:   for(h=1; h <=nhstepm; h++){
                   3373:     for(d=1; d <=hstepm; d++){
                   3374:       newm=savm;
                   3375:       /* Covariates have to be included here again */
                   3376:       cov[1]=1.;
1.271     brouard  3377:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3378:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3379:       cov[2]=agexact;
                   3380:       if(nagesqr==1)
1.222     brouard  3381:        cov[3]= agexact*agexact;
1.266     brouard  3382:       for (k=1; k<=cptcovn;k++){
                   3383:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3384:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3385:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3386:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3387:       }
1.267     brouard  3388:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3389:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3390:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3391:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3392:       }
                   3393:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3394:        if(Dummy[Tvar[Tage[k]]]){
                   3395:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3396:        } else{
                   3397:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3398:        }
                   3399:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3400:       }
                   3401:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3402:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3403:       }                        
1.217     brouard  3404:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3405:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3406: 
1.218     brouard  3407:       /* Careful transposed matrix */
1.266     brouard  3408:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3409:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3410:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3411:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3412:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3413:       /* if((int)age == 70){ */
                   3414:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3415:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3416:       /*         printf("%d pmmij ",i); */
                   3417:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3418:       /*           printf("%f ",pmmij[i][j]); */
                   3419:       /*         } */
                   3420:       /*         printf(" oldm "); */
                   3421:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3422:       /*           printf("%f ",oldm[i][j]); */
                   3423:       /*         } */
                   3424:       /*         printf("\n"); */
                   3425:       /*       } */
                   3426:       /* } */
                   3427:       savm=oldm;
                   3428:       oldm=newm;
                   3429:     }
                   3430:     for(i=1; i<=nlstate+ndeath; i++)
                   3431:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3432:        po[i][j][h]=newm[i][j];
1.268     brouard  3433:        /* if(h==nhstepm) */
                   3434:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3435:       }
1.268     brouard  3436:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3437:   } /* end h */
1.268     brouard  3438:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3439:   return po;
                   3440: }
                   3441: 
                   3442: 
1.162     brouard  3443: #ifdef NLOPT
                   3444:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3445:   double fret;
                   3446:   double *xt;
                   3447:   int j;
                   3448:   myfunc_data *d2 = (myfunc_data *) pd;
                   3449: /* xt = (p1-1); */
                   3450:   xt=vector(1,n); 
                   3451:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3452: 
                   3453:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3454:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3455:   printf("Function = %.12lf ",fret);
                   3456:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3457:   printf("\n");
                   3458:  free_vector(xt,1,n);
                   3459:   return fret;
                   3460: }
                   3461: #endif
1.126     brouard  3462: 
                   3463: /*************** log-likelihood *************/
                   3464: double func( double *x)
                   3465: {
1.226     brouard  3466:   int i, ii, j, k, mi, d, kk;
                   3467:   int ioffset=0;
                   3468:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3469:   double **out;
                   3470:   double lli; /* Individual log likelihood */
                   3471:   int s1, s2;
1.228     brouard  3472:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3473:   double bbh, survp;
                   3474:   long ipmx;
                   3475:   double agexact;
                   3476:   /*extern weight */
                   3477:   /* We are differentiating ll according to initial status */
                   3478:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3479:   /*for(i=1;i<imx;i++) 
                   3480:     printf(" %d\n",s[4][i]);
                   3481:   */
1.162     brouard  3482: 
1.226     brouard  3483:   ++countcallfunc;
1.162     brouard  3484: 
1.226     brouard  3485:   cov[1]=1.;
1.126     brouard  3486: 
1.226     brouard  3487:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3488:   ioffset=0;
1.226     brouard  3489:   if(mle==1){
                   3490:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3491:       /* Computes the values of the ncovmodel covariates of the model
                   3492:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3493:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3494:         to be observed in j being in i according to the model.
                   3495:       */
1.243     brouard  3496:       ioffset=2+nagesqr ;
1.233     brouard  3497:    /* Fixed */
1.234     brouard  3498:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3499:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3500:       }
1.226     brouard  3501:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3502:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3503:         has been calculated etc */
                   3504:       /* For an individual i, wav[i] gives the number of effective waves */
                   3505:       /* We compute the contribution to Likelihood of each effective transition
                   3506:         mw[mi][i] is real wave of the mi th effectve wave */
                   3507:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3508:         s2=s[mw[mi+1][i]][i];
                   3509:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3510:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3511:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3512:       */
                   3513:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3514:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3515:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3516:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3517:        }
                   3518:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3519:          for (j=1;j<=nlstate+ndeath;j++){
                   3520:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3521:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3522:          }
                   3523:        for(d=0; d<dh[mi][i]; d++){
                   3524:          newm=savm;
                   3525:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3526:          cov[2]=agexact;
                   3527:          if(nagesqr==1)
                   3528:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3529:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3530:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3531:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3532:          else
                   3533:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3534:          }
                   3535:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3536:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3537:          savm=oldm;
                   3538:          oldm=newm;
                   3539:        } /* end mult */
                   3540:        
                   3541:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3542:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3543:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3544:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3545:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3546:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3547:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3548:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3549:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3550:                                 * -stepm/2 to stepm/2 .
                   3551:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3552:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3553:                                 */
1.234     brouard  3554:        s1=s[mw[mi][i]][i];
                   3555:        s2=s[mw[mi+1][i]][i];
                   3556:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3557:        /* bias bh is positive if real duration
                   3558:         * is higher than the multiple of stepm and negative otherwise.
                   3559:         */
                   3560:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3561:        if( s2 > nlstate){ 
                   3562:          /* i.e. if s2 is a death state and if the date of death is known 
                   3563:             then the contribution to the likelihood is the probability to 
                   3564:             die between last step unit time and current  step unit time, 
                   3565:             which is also equal to probability to die before dh 
                   3566:             minus probability to die before dh-stepm . 
                   3567:             In version up to 0.92 likelihood was computed
                   3568:             as if date of death was unknown. Death was treated as any other
                   3569:             health state: the date of the interview describes the actual state
                   3570:             and not the date of a change in health state. The former idea was
                   3571:             to consider that at each interview the state was recorded
                   3572:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3573:             introduced the exact date of death then we should have modified
                   3574:             the contribution of an exact death to the likelihood. This new
                   3575:             contribution is smaller and very dependent of the step unit
                   3576:             stepm. It is no more the probability to die between last interview
                   3577:             and month of death but the probability to survive from last
                   3578:             interview up to one month before death multiplied by the
                   3579:             probability to die within a month. Thanks to Chris
                   3580:             Jackson for correcting this bug.  Former versions increased
                   3581:             mortality artificially. The bad side is that we add another loop
                   3582:             which slows down the processing. The difference can be up to 10%
                   3583:             lower mortality.
                   3584:          */
                   3585:          /* If, at the beginning of the maximization mostly, the
                   3586:             cumulative probability or probability to be dead is
                   3587:             constant (ie = 1) over time d, the difference is equal to
                   3588:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3589:             s1 at precedent wave, to be dead a month before current
                   3590:             wave is equal to probability, being at state s1 at
                   3591:             precedent wave, to be dead at mont of the current
                   3592:             wave. Then the observed probability (that this person died)
                   3593:             is null according to current estimated parameter. In fact,
                   3594:             it should be very low but not zero otherwise the log go to
                   3595:             infinity.
                   3596:          */
1.183     brouard  3597: /* #ifdef INFINITYORIGINAL */
                   3598: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3599: /* #else */
                   3600: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3601: /*         lli=log(mytinydouble); */
                   3602: /*       else */
                   3603: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3604: /* #endif */
1.226     brouard  3605:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3606:          
1.226     brouard  3607:        } else if  ( s2==-1 ) { /* alive */
                   3608:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3609:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3610:          /*survp += out[s1][j]; */
                   3611:          lli= log(survp);
                   3612:        }
                   3613:        else if  (s2==-4) { 
                   3614:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3615:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3616:          lli= log(survp); 
                   3617:        } 
                   3618:        else if  (s2==-5) { 
                   3619:          for (j=1,survp=0. ; j<=2; j++)  
                   3620:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3621:          lli= log(survp); 
                   3622:        } 
                   3623:        else{
                   3624:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3625:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3626:        } 
                   3627:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3628:        /*if(lli ==000.0)*/
                   3629:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3630:        ipmx +=1;
                   3631:        sw += weight[i];
                   3632:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3633:        /* if (lli < log(mytinydouble)){ */
                   3634:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3635:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3636:        /* } */
                   3637:       } /* end of wave */
                   3638:     } /* end of individual */
                   3639:   }  else if(mle==2){
                   3640:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3641:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3642:       for(mi=1; mi<= wav[i]-1; mi++){
                   3643:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3644:          for (j=1;j<=nlstate+ndeath;j++){
                   3645:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3646:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3647:          }
                   3648:        for(d=0; d<=dh[mi][i]; d++){
                   3649:          newm=savm;
                   3650:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3651:          cov[2]=agexact;
                   3652:          if(nagesqr==1)
                   3653:            cov[3]= agexact*agexact;
                   3654:          for (kk=1; kk<=cptcovage;kk++) {
                   3655:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3656:          }
                   3657:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3658:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3659:          savm=oldm;
                   3660:          oldm=newm;
                   3661:        } /* end mult */
                   3662:       
                   3663:        s1=s[mw[mi][i]][i];
                   3664:        s2=s[mw[mi+1][i]][i];
                   3665:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3666:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3667:        ipmx +=1;
                   3668:        sw += weight[i];
                   3669:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3670:       } /* end of wave */
                   3671:     } /* end of individual */
                   3672:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3673:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3674:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3675:       for(mi=1; mi<= wav[i]-1; mi++){
                   3676:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3677:          for (j=1;j<=nlstate+ndeath;j++){
                   3678:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3679:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3680:          }
                   3681:        for(d=0; d<dh[mi][i]; d++){
                   3682:          newm=savm;
                   3683:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3684:          cov[2]=agexact;
                   3685:          if(nagesqr==1)
                   3686:            cov[3]= agexact*agexact;
                   3687:          for (kk=1; kk<=cptcovage;kk++) {
                   3688:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3689:          }
                   3690:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3691:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3692:          savm=oldm;
                   3693:          oldm=newm;
                   3694:        } /* end mult */
                   3695:       
                   3696:        s1=s[mw[mi][i]][i];
                   3697:        s2=s[mw[mi+1][i]][i];
                   3698:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3699:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3700:        ipmx +=1;
                   3701:        sw += weight[i];
                   3702:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3703:       } /* end of wave */
                   3704:     } /* end of individual */
                   3705:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3706:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3707:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3708:       for(mi=1; mi<= wav[i]-1; mi++){
                   3709:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3710:          for (j=1;j<=nlstate+ndeath;j++){
                   3711:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3712:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3713:          }
                   3714:        for(d=0; d<dh[mi][i]; d++){
                   3715:          newm=savm;
                   3716:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3717:          cov[2]=agexact;
                   3718:          if(nagesqr==1)
                   3719:            cov[3]= agexact*agexact;
                   3720:          for (kk=1; kk<=cptcovage;kk++) {
                   3721:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3722:          }
1.126     brouard  3723:        
1.226     brouard  3724:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3725:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3726:          savm=oldm;
                   3727:          oldm=newm;
                   3728:        } /* end mult */
                   3729:       
                   3730:        s1=s[mw[mi][i]][i];
                   3731:        s2=s[mw[mi+1][i]][i];
                   3732:        if( s2 > nlstate){ 
                   3733:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3734:        } else if  ( s2==-1 ) { /* alive */
                   3735:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3736:            survp += out[s1][j];
                   3737:          lli= log(survp);
                   3738:        }else{
                   3739:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3740:        }
                   3741:        ipmx +=1;
                   3742:        sw += weight[i];
                   3743:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3744: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3745:       } /* end of wave */
                   3746:     } /* end of individual */
                   3747:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3748:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3749:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3750:       for(mi=1; mi<= wav[i]-1; mi++){
                   3751:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3752:          for (j=1;j<=nlstate+ndeath;j++){
                   3753:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3754:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3755:          }
                   3756:        for(d=0; d<dh[mi][i]; d++){
                   3757:          newm=savm;
                   3758:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3759:          cov[2]=agexact;
                   3760:          if(nagesqr==1)
                   3761:            cov[3]= agexact*agexact;
                   3762:          for (kk=1; kk<=cptcovage;kk++) {
                   3763:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3764:          }
1.126     brouard  3765:        
1.226     brouard  3766:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3767:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3768:          savm=oldm;
                   3769:          oldm=newm;
                   3770:        } /* end mult */
                   3771:       
                   3772:        s1=s[mw[mi][i]][i];
                   3773:        s2=s[mw[mi+1][i]][i];
                   3774:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3775:        ipmx +=1;
                   3776:        sw += weight[i];
                   3777:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3778:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3779:       } /* end of wave */
                   3780:     } /* end of individual */
                   3781:   } /* End of if */
                   3782:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3783:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3784:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3785:   return -l;
1.126     brouard  3786: }
                   3787: 
                   3788: /*************** log-likelihood *************/
                   3789: double funcone( double *x)
                   3790: {
1.228     brouard  3791:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3792:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3793:   int ioffset=0;
1.131     brouard  3794:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3795:   double **out;
                   3796:   double lli; /* Individual log likelihood */
                   3797:   double llt;
                   3798:   int s1, s2;
1.228     brouard  3799:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3800: 
1.126     brouard  3801:   double bbh, survp;
1.187     brouard  3802:   double agexact;
1.214     brouard  3803:   double agebegin, ageend;
1.126     brouard  3804:   /*extern weight */
                   3805:   /* We are differentiating ll according to initial status */
                   3806:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3807:   /*for(i=1;i<imx;i++) 
                   3808:     printf(" %d\n",s[4][i]);
                   3809:   */
                   3810:   cov[1]=1.;
                   3811: 
                   3812:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3813:   ioffset=0;
                   3814:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3815:     /* ioffset=2+nagesqr+cptcovage; */
                   3816:     ioffset=2+nagesqr;
1.232     brouard  3817:     /* Fixed */
1.224     brouard  3818:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3819:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3820:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3821:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3822: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3823: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3824: /*    cov[2+6]=covar[2][i]; V2  */
                   3825: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3826: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3827: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3828: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3829: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3830: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3831:     }
1.232     brouard  3832:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3833:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3834:     /* } */
1.231     brouard  3835:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3836:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3837:     /* } */
1.225     brouard  3838:     
1.233     brouard  3839: 
                   3840:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3841:     /* Wave varying (but not age varying) */
                   3842:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3843:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3844:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3845:       }
1.232     brouard  3846:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3847:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3848:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3849:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3850:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3851:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3852:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3853:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3854:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3855:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3856:       /* } */
1.126     brouard  3857:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3858:        for (j=1;j<=nlstate+ndeath;j++){
                   3859:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3860:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3861:        }
1.214     brouard  3862:       
                   3863:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3864:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3865:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3866:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3867:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3868:          and mw[mi+1][i]. dh depends on stepm.*/
                   3869:        newm=savm;
1.247     brouard  3870:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3871:        cov[2]=agexact;
                   3872:        if(nagesqr==1)
                   3873:          cov[3]= agexact*agexact;
                   3874:        for (kk=1; kk<=cptcovage;kk++) {
                   3875:          if(!FixedV[Tvar[Tage[kk]]])
                   3876:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3877:          else
                   3878:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3879:        }
                   3880:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3881:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3882:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3883:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3884:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3885:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3886:        savm=oldm;
                   3887:        oldm=newm;
1.126     brouard  3888:       } /* end mult */
                   3889:       
                   3890:       s1=s[mw[mi][i]][i];
                   3891:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3892:       /* if(s2==-1){ */
1.268     brouard  3893:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3894:       /*       /\* exit(1); *\/ */
                   3895:       /* } */
1.126     brouard  3896:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3897:       /* bias is positive if real duration
                   3898:        * is higher than the multiple of stepm and negative otherwise.
                   3899:        */
                   3900:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3901:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3902:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3903:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3904:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3905:        lli= log(survp);
1.126     brouard  3906:       }else if (mle==1){
1.242     brouard  3907:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3908:       } else if(mle==2){
1.242     brouard  3909:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3910:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3911:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3912:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3913:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3914:       } else{  /* mle=0 back to 1 */
1.242     brouard  3915:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3916:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3917:       } /* End of if */
                   3918:       ipmx +=1;
                   3919:       sw += weight[i];
                   3920:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3921:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3922:       if(globpr){
1.246     brouard  3923:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3924:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3925:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3926:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3927:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3928:          llt +=ll[k]*gipmx/gsw;
                   3929:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3930:        }
                   3931:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3932:       }
1.232     brouard  3933:        } /* end of wave */
                   3934: } /* end of individual */
                   3935: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3936: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3937: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3938: if(globpr==0){ /* First time we count the contributions and weights */
                   3939:        gipmx=ipmx;
                   3940:        gsw=sw;
                   3941: }
                   3942: return -l;
1.126     brouard  3943: }
                   3944: 
                   3945: 
                   3946: /*************** function likelione ***********/
1.292     brouard  3947: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  3948: {
                   3949:   /* This routine should help understanding what is done with 
                   3950:      the selection of individuals/waves and
                   3951:      to check the exact contribution to the likelihood.
                   3952:      Plotting could be done.
                   3953:    */
                   3954:   int k;
                   3955: 
                   3956:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3957:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3958:     strcat(fileresilk,fileresu);
1.126     brouard  3959:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3960:       printf("Problem with resultfile: %s\n", fileresilk);
                   3961:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3962:     }
1.214     brouard  3963:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3964:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3965:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3966:     for(k=1; k<=nlstate; k++) 
                   3967:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3968:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3969:   }
                   3970: 
1.292     brouard  3971:   *fretone=(*func)(p);
1.126     brouard  3972:   if(*globpri !=0){
                   3973:     fclose(ficresilk);
1.205     brouard  3974:     if (mle ==0)
                   3975:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3976:     else if(mle >=1)
                   3977:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3978:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3979:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3980:       
                   3981:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3982:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3983: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3984:     }
1.207     brouard  3985:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  3986: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3987:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  3988: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  3989:     fflush(fichtm);
1.205     brouard  3990:   }
1.126     brouard  3991:   return;
                   3992: }
                   3993: 
                   3994: 
                   3995: /*********** Maximum Likelihood Estimation ***************/
                   3996: 
                   3997: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   3998: {
1.165     brouard  3999:   int i,j, iter=0;
1.126     brouard  4000:   double **xi;
                   4001:   double fret;
                   4002:   double fretone; /* Only one call to likelihood */
                   4003:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  4004: 
                   4005: #ifdef NLOPT
                   4006:   int creturn;
                   4007:   nlopt_opt opt;
                   4008:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   4009:   double *lb;
                   4010:   double minf; /* the minimum objective value, upon return */
                   4011:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   4012:   myfunc_data dinst, *d = &dinst;
                   4013: #endif
                   4014: 
                   4015: 
1.126     brouard  4016:   xi=matrix(1,npar,1,npar);
                   4017:   for (i=1;i<=npar;i++)
                   4018:     for (j=1;j<=npar;j++)
                   4019:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   4020:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  4021:   strcpy(filerespow,"POW_"); 
1.126     brouard  4022:   strcat(filerespow,fileres);
                   4023:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   4024:     printf("Problem with resultfile: %s\n", filerespow);
                   4025:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   4026:   }
                   4027:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   4028:   for (i=1;i<=nlstate;i++)
                   4029:     for(j=1;j<=nlstate+ndeath;j++)
                   4030:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   4031:   fprintf(ficrespow,"\n");
1.162     brouard  4032: #ifdef POWELL
1.126     brouard  4033:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  4034: #endif
1.126     brouard  4035: 
1.162     brouard  4036: #ifdef NLOPT
                   4037: #ifdef NEWUOA
                   4038:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   4039: #else
                   4040:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   4041: #endif
                   4042:   lb=vector(0,npar-1);
                   4043:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   4044:   nlopt_set_lower_bounds(opt, lb);
                   4045:   nlopt_set_initial_step1(opt, 0.1);
                   4046:   
                   4047:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   4048:   d->function = func;
                   4049:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   4050:   nlopt_set_min_objective(opt, myfunc, d);
                   4051:   nlopt_set_xtol_rel(opt, ftol);
                   4052:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4053:     printf("nlopt failed! %d\n",creturn); 
                   4054:   }
                   4055:   else {
                   4056:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4057:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4058:     iter=1; /* not equal */
                   4059:   }
                   4060:   nlopt_destroy(opt);
                   4061: #endif
1.126     brouard  4062:   free_matrix(xi,1,npar,1,npar);
                   4063:   fclose(ficrespow);
1.203     brouard  4064:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4065:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4066:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4067: 
                   4068: }
                   4069: 
                   4070: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4071: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4072: {
                   4073:   double  **a,**y,*x,pd;
1.203     brouard  4074:   /* double **hess; */
1.164     brouard  4075:   int i, j;
1.126     brouard  4076:   int *indx;
                   4077: 
                   4078:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4079:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4080:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4081:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4082:   double gompertz(double p[]);
1.203     brouard  4083:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4084: 
                   4085:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4086:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4087:   for (i=1;i<=npar;i++){
1.203     brouard  4088:     printf("%d-",i);fflush(stdout);
                   4089:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4090:    
                   4091:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4092:     
                   4093:     /*  printf(" %f ",p[i]);
                   4094:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4095:   }
                   4096:   
                   4097:   for (i=1;i<=npar;i++) {
                   4098:     for (j=1;j<=npar;j++)  {
                   4099:       if (j>i) { 
1.203     brouard  4100:        printf(".%d-%d",i,j);fflush(stdout);
                   4101:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4102:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4103:        
                   4104:        hess[j][i]=hess[i][j];    
                   4105:        /*printf(" %lf ",hess[i][j]);*/
                   4106:       }
                   4107:     }
                   4108:   }
                   4109:   printf("\n");
                   4110:   fprintf(ficlog,"\n");
                   4111: 
                   4112:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4113:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4114:   
                   4115:   a=matrix(1,npar,1,npar);
                   4116:   y=matrix(1,npar,1,npar);
                   4117:   x=vector(1,npar);
                   4118:   indx=ivector(1,npar);
                   4119:   for (i=1;i<=npar;i++)
                   4120:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4121:   ludcmp(a,npar,indx,&pd);
                   4122: 
                   4123:   for (j=1;j<=npar;j++) {
                   4124:     for (i=1;i<=npar;i++) x[i]=0;
                   4125:     x[j]=1;
                   4126:     lubksb(a,npar,indx,x);
                   4127:     for (i=1;i<=npar;i++){ 
                   4128:       matcov[i][j]=x[i];
                   4129:     }
                   4130:   }
                   4131: 
                   4132:   printf("\n#Hessian matrix#\n");
                   4133:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4134:   for (i=1;i<=npar;i++) { 
                   4135:     for (j=1;j<=npar;j++) { 
1.203     brouard  4136:       printf("%.6e ",hess[i][j]);
                   4137:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4138:     }
                   4139:     printf("\n");
                   4140:     fprintf(ficlog,"\n");
                   4141:   }
                   4142: 
1.203     brouard  4143:   /* printf("\n#Covariance matrix#\n"); */
                   4144:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4145:   /* for (i=1;i<=npar;i++) {  */
                   4146:   /*   for (j=1;j<=npar;j++) {  */
                   4147:   /*     printf("%.6e ",matcov[i][j]); */
                   4148:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4149:   /*   } */
                   4150:   /*   printf("\n"); */
                   4151:   /*   fprintf(ficlog,"\n"); */
                   4152:   /* } */
                   4153: 
1.126     brouard  4154:   /* Recompute Inverse */
1.203     brouard  4155:   /* for (i=1;i<=npar;i++) */
                   4156:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4157:   /* ludcmp(a,npar,indx,&pd); */
                   4158: 
                   4159:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4160: 
                   4161:   /* for (j=1;j<=npar;j++) { */
                   4162:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4163:   /*   x[j]=1; */
                   4164:   /*   lubksb(a,npar,indx,x); */
                   4165:   /*   for (i=1;i<=npar;i++){  */
                   4166:   /*     y[i][j]=x[i]; */
                   4167:   /*     printf("%.3e ",y[i][j]); */
                   4168:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4169:   /*   } */
                   4170:   /*   printf("\n"); */
                   4171:   /*   fprintf(ficlog,"\n"); */
                   4172:   /* } */
                   4173: 
                   4174:   /* Verifying the inverse matrix */
                   4175: #ifdef DEBUGHESS
                   4176:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4177: 
1.203     brouard  4178:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4179:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4180: 
                   4181:   for (j=1;j<=npar;j++) {
                   4182:     for (i=1;i<=npar;i++){ 
1.203     brouard  4183:       printf("%.2f ",y[i][j]);
                   4184:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4185:     }
                   4186:     printf("\n");
                   4187:     fprintf(ficlog,"\n");
                   4188:   }
1.203     brouard  4189: #endif
1.126     brouard  4190: 
                   4191:   free_matrix(a,1,npar,1,npar);
                   4192:   free_matrix(y,1,npar,1,npar);
                   4193:   free_vector(x,1,npar);
                   4194:   free_ivector(indx,1,npar);
1.203     brouard  4195:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4196: 
                   4197: 
                   4198: }
                   4199: 
                   4200: /*************** hessian matrix ****************/
                   4201: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4202: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4203:   int i;
                   4204:   int l=1, lmax=20;
1.203     brouard  4205:   double k1,k2, res, fx;
1.132     brouard  4206:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4207:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4208:   int k=0,kmax=10;
                   4209:   double l1;
                   4210: 
                   4211:   fx=func(x);
                   4212:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4213:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4214:     l1=pow(10,l);
                   4215:     delts=delt;
                   4216:     for(k=1 ; k <kmax; k=k+1){
                   4217:       delt = delta*(l1*k);
                   4218:       p2[theta]=x[theta] +delt;
1.145     brouard  4219:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4220:       p2[theta]=x[theta]-delt;
                   4221:       k2=func(p2)-fx;
                   4222:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4223:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4224:       
1.203     brouard  4225: #ifdef DEBUGHESSII
1.126     brouard  4226:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4227:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4228: #endif
                   4229:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4230:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4231:        k=kmax;
                   4232:       }
                   4233:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4234:        k=kmax; l=lmax*10;
1.126     brouard  4235:       }
                   4236:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4237:        delts=delt;
                   4238:       }
1.203     brouard  4239:     } /* End loop k */
1.126     brouard  4240:   }
                   4241:   delti[theta]=delts;
                   4242:   return res; 
                   4243:   
                   4244: }
                   4245: 
1.203     brouard  4246: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4247: {
                   4248:   int i;
1.164     brouard  4249:   int l=1, lmax=20;
1.126     brouard  4250:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4251:   double p2[MAXPARM+1];
1.203     brouard  4252:   int k, kmax=1;
                   4253:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4254: 
                   4255:   int firstime=0;
1.203     brouard  4256:   
1.126     brouard  4257:   fx=func(x);
1.203     brouard  4258:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4259:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4260:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4261:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4262:     k1=func(p2)-fx;
                   4263:   
1.203     brouard  4264:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4265:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4266:     k2=func(p2)-fx;
                   4267:   
1.203     brouard  4268:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4269:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4270:     k3=func(p2)-fx;
                   4271:   
1.203     brouard  4272:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4273:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4274:     k4=func(p2)-fx;
1.203     brouard  4275:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4276:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4277:       firstime=1;
1.203     brouard  4278:       kmax=kmax+10;
1.208     brouard  4279:     }
                   4280:     if(kmax >=10 || firstime ==1){
1.246     brouard  4281:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4282:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4283:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4284:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4285:     }
                   4286: #ifdef DEBUGHESSIJ
                   4287:     v1=hess[thetai][thetai];
                   4288:     v2=hess[thetaj][thetaj];
                   4289:     cv12=res;
                   4290:     /* Computing eigen value of Hessian matrix */
                   4291:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4292:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4293:     if ((lc2 <0) || (lc1 <0) ){
                   4294:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4295:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4296:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4297:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4298:     }
1.126     brouard  4299: #endif
                   4300:   }
                   4301:   return res;
                   4302: }
                   4303: 
1.203     brouard  4304:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4305: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4306: /* { */
                   4307: /*   int i; */
                   4308: /*   int l=1, lmax=20; */
                   4309: /*   double k1,k2,k3,k4,res,fx; */
                   4310: /*   double p2[MAXPARM+1]; */
                   4311: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4312: /*   int k=0,kmax=10; */
                   4313: /*   double l1; */
                   4314:   
                   4315: /*   fx=func(x); */
                   4316: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4317: /*     l1=pow(10,l); */
                   4318: /*     delts=delt; */
                   4319: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4320: /*       delt = delti*(l1*k); */
                   4321: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4322: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4323: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4324: /*       k1=func(p2)-fx; */
                   4325:       
                   4326: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4327: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4328: /*       k2=func(p2)-fx; */
                   4329:       
                   4330: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4331: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4332: /*       k3=func(p2)-fx; */
                   4333:       
                   4334: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4335: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4336: /*       k4=func(p2)-fx; */
                   4337: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4338: /* #ifdef DEBUGHESSIJ */
                   4339: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4340: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4341: /* #endif */
                   4342: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4343: /*     k=kmax; */
                   4344: /*       } */
                   4345: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4346: /*     k=kmax; l=lmax*10; */
                   4347: /*       } */
                   4348: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4349: /*     delts=delt; */
                   4350: /*       } */
                   4351: /*     } /\* End loop k *\/ */
                   4352: /*   } */
                   4353: /*   delti[theta]=delts; */
                   4354: /*   return res;  */
                   4355: /* } */
                   4356: 
                   4357: 
1.126     brouard  4358: /************** Inverse of matrix **************/
                   4359: void ludcmp(double **a, int n, int *indx, double *d) 
                   4360: { 
                   4361:   int i,imax,j,k; 
                   4362:   double big,dum,sum,temp; 
                   4363:   double *vv; 
                   4364:  
                   4365:   vv=vector(1,n); 
                   4366:   *d=1.0; 
                   4367:   for (i=1;i<=n;i++) { 
                   4368:     big=0.0; 
                   4369:     for (j=1;j<=n;j++) 
                   4370:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4371:     if (big == 0.0){
                   4372:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4373:       for (j=1;j<=n;j++) {
                   4374:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4375:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4376:       }
                   4377:       fflush(ficlog);
                   4378:       fclose(ficlog);
                   4379:       nrerror("Singular matrix in routine ludcmp"); 
                   4380:     }
1.126     brouard  4381:     vv[i]=1.0/big; 
                   4382:   } 
                   4383:   for (j=1;j<=n;j++) { 
                   4384:     for (i=1;i<j;i++) { 
                   4385:       sum=a[i][j]; 
                   4386:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4387:       a[i][j]=sum; 
                   4388:     } 
                   4389:     big=0.0; 
                   4390:     for (i=j;i<=n;i++) { 
                   4391:       sum=a[i][j]; 
                   4392:       for (k=1;k<j;k++) 
                   4393:        sum -= a[i][k]*a[k][j]; 
                   4394:       a[i][j]=sum; 
                   4395:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4396:        big=dum; 
                   4397:        imax=i; 
                   4398:       } 
                   4399:     } 
                   4400:     if (j != imax) { 
                   4401:       for (k=1;k<=n;k++) { 
                   4402:        dum=a[imax][k]; 
                   4403:        a[imax][k]=a[j][k]; 
                   4404:        a[j][k]=dum; 
                   4405:       } 
                   4406:       *d = -(*d); 
                   4407:       vv[imax]=vv[j]; 
                   4408:     } 
                   4409:     indx[j]=imax; 
                   4410:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4411:     if (j != n) { 
                   4412:       dum=1.0/(a[j][j]); 
                   4413:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4414:     } 
                   4415:   } 
                   4416:   free_vector(vv,1,n);  /* Doesn't work */
                   4417: ;
                   4418: } 
                   4419: 
                   4420: void lubksb(double **a, int n, int *indx, double b[]) 
                   4421: { 
                   4422:   int i,ii=0,ip,j; 
                   4423:   double sum; 
                   4424:  
                   4425:   for (i=1;i<=n;i++) { 
                   4426:     ip=indx[i]; 
                   4427:     sum=b[ip]; 
                   4428:     b[ip]=b[i]; 
                   4429:     if (ii) 
                   4430:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4431:     else if (sum) ii=i; 
                   4432:     b[i]=sum; 
                   4433:   } 
                   4434:   for (i=n;i>=1;i--) { 
                   4435:     sum=b[i]; 
                   4436:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4437:     b[i]=sum/a[i][i]; 
                   4438:   } 
                   4439: } 
                   4440: 
                   4441: void pstamp(FILE *fichier)
                   4442: {
1.196     brouard  4443:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4444: }
                   4445: 
1.297     brouard  4446: void date2dmy(double date,double *day, double *month, double *year){
                   4447:   double yp=0., yp1=0., yp2=0.;
                   4448:   
                   4449:   yp1=modf(date,&yp);/* extracts integral of date in yp  and
                   4450:                        fractional in yp1 */
                   4451:   *year=yp;
                   4452:   yp2=modf((yp1*12),&yp);
                   4453:   *month=yp;
                   4454:   yp1=modf((yp2*30.5),&yp);
                   4455:   *day=yp;
                   4456:   if(*day==0) *day=1;
                   4457:   if(*month==0) *month=1;
                   4458: }
                   4459: 
1.253     brouard  4460: 
                   4461: 
1.126     brouard  4462: /************ Frequencies ********************/
1.251     brouard  4463: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4464:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4465:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4466: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4467:   
1.265     brouard  4468:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4469:   int iind=0, iage=0;
                   4470:   int mi; /* Effective wave */
                   4471:   int first;
                   4472:   double ***freq; /* Frequencies */
1.268     brouard  4473:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4474:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4475:   double *meanq, *stdq, *idq;
1.226     brouard  4476:   double **meanqt;
                   4477:   double *pp, **prop, *posprop, *pospropt;
                   4478:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4479:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4480:   double agebegin, ageend;
                   4481:     
                   4482:   pp=vector(1,nlstate);
1.251     brouard  4483:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4484:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4485:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4486:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4487:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4488:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4489:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4490:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4491:   strcpy(fileresp,"P_");
                   4492:   strcat(fileresp,fileresu);
                   4493:   /*strcat(fileresphtm,fileresu);*/
                   4494:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4495:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4496:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4497:     exit(0);
                   4498:   }
1.240     brouard  4499:   
1.226     brouard  4500:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4501:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4502:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4503:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4504:     fflush(ficlog);
                   4505:     exit(70); 
                   4506:   }
                   4507:   else{
                   4508:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4509: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4510: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4511:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4512:   }
1.237     brouard  4513:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4514:   
1.226     brouard  4515:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4516:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4517:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4518:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4519:     fflush(ficlog);
                   4520:     exit(70); 
1.240     brouard  4521:   } else{
1.226     brouard  4522:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4523: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4524: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4525:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4526:   }
1.240     brouard  4527:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4528:   
1.253     brouard  4529:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4530:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4531:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4532:   j1=0;
1.126     brouard  4533:   
1.227     brouard  4534:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4535:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4536:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4537:   
                   4538:   
1.226     brouard  4539:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4540:      reference=low_education V1=0,V2=0
                   4541:      med_educ                V1=1 V2=0, 
                   4542:      high_educ               V1=0 V2=1
                   4543:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4544:   */
1.249     brouard  4545:   dateintsum=0;
                   4546:   k2cpt=0;
                   4547: 
1.253     brouard  4548:   if(cptcoveff == 0 )
1.265     brouard  4549:     nl=1;  /* Constant and age model only */
1.253     brouard  4550:   else
                   4551:     nl=2;
1.265     brouard  4552: 
                   4553:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4554:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4555:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4556:    *     freq[s1][s2][iage] =0.
                   4557:    *     Loop on iind
                   4558:    *       ++freq[s1][s2][iage] weighted
                   4559:    *     end iind
                   4560:    *     if covariate and j!0
                   4561:    *       headers Variable on one line
                   4562:    *     endif cov j!=0
                   4563:    *     header of frequency table by age
                   4564:    *     Loop on age
                   4565:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4566:    *       pos+=freq[s1][s2][iage] weighted
                   4567:    *       Loop on s1 initial state
                   4568:    *         fprintf(ficresp
                   4569:    *       end s1
                   4570:    *     end age
                   4571:    *     if j!=0 computes starting values
                   4572:    *     end compute starting values
                   4573:    *   end j1
                   4574:    * end nl 
                   4575:    */
1.253     brouard  4576:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4577:     if(nj==1)
                   4578:       j=0;  /* First pass for the constant */
1.265     brouard  4579:     else{
1.253     brouard  4580:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4581:     }
1.251     brouard  4582:     first=1;
1.265     brouard  4583:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4584:       posproptt=0.;
                   4585:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4586:        scanf("%d", i);*/
                   4587:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4588:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4589:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4590:            freq[i][s2][m]=0;
1.251     brouard  4591:       
                   4592:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4593:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4594:          prop[i][m]=0;
                   4595:        posprop[i]=0;
                   4596:        pospropt[i]=0;
                   4597:       }
1.283     brouard  4598:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4599:         idq[z1]=0.;
                   4600:         meanq[z1]=0.;
                   4601:         stdq[z1]=0.;
1.283     brouard  4602:       }
                   4603:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4604:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4605:       /*         meanqt[m][z1]=0.; */
                   4606:       /*       } */
                   4607:       /* }       */
1.251     brouard  4608:       /* dateintsum=0; */
                   4609:       /* k2cpt=0; */
                   4610:       
1.265     brouard  4611:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4612:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4613:        bool=1;
                   4614:        if(j !=0){
                   4615:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4616:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4617:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4618:                /* if(Tvaraff[z1] ==-20){ */
                   4619:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4620:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4621:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4622:                /* }else  */
                   4623:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4624:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4625:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4626:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4627:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4628:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4629:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4630:                } /* Onlyf fixed */
                   4631:              } /* end z1 */
                   4632:            } /* cptcovn > 0 */
                   4633:          } /* end any */
                   4634:        }/* end j==0 */
1.265     brouard  4635:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4636:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4637:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4638:            m=mw[mi][iind];
                   4639:            if(j!=0){
                   4640:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4641:                for (z1=1; z1<=cptcoveff; z1++) {
                   4642:                  if( Fixed[Tmodelind[z1]]==1){
                   4643:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4644:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4645:                                                                                      value is -1, we don't select. It differs from the 
                   4646:                                                                                      constant and age model which counts them. */
                   4647:                      bool=0; /* not selected */
                   4648:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4649:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4650:                      bool=0;
                   4651:                    }
                   4652:                  }
                   4653:                }
                   4654:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4655:            } /* end j==0 */
                   4656:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4657:            if(bool==1){ /*Selected */
1.251     brouard  4658:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4659:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4660:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4661:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4662:              if(m >=firstpass && m <=lastpass){
                   4663:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4664:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4665:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4666:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4667:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4668:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4669:                if (m<lastpass) {
                   4670:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4671:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4672:                  if(s[m][iind]==-1)
                   4673:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4674:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.284     brouard  4675:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean */
                   4676:                    idq[z1]=idq[z1]+weight[iind];
                   4677:                    meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4678:                    stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4679:                  }
1.251     brouard  4680:                  /* if((int)agev[m][iind] == 55) */
                   4681:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4682:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4683:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4684:                }
1.251     brouard  4685:              } /* end if between passes */  
                   4686:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4687:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4688:                k2cpt++;
                   4689:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4690:              }
1.251     brouard  4691:            }else{
                   4692:              bool=1;
                   4693:            }/* end bool 2 */
                   4694:          } /* end m */
1.284     brouard  4695:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4696:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4697:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4698:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4699:          /* } */
1.251     brouard  4700:        } /* end bool */
                   4701:       } /* end iind = 1 to imx */
                   4702:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4703:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4704:       
                   4705:       
                   4706:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4707:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4708:         pstamp(ficresp);
1.251     brouard  4709:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4710:         pstamp(ficresp);
1.251     brouard  4711:        printf( "\n#********** Variable "); 
                   4712:        fprintf(ficresp, "\n#********** Variable "); 
                   4713:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4714:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4715:        fprintf(ficlog, "\n#********** Variable "); 
                   4716:        for (z1=1; z1<=cptcoveff; z1++){
                   4717:          if(!FixedV[Tvaraff[z1]]){
                   4718:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4719:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4720:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4721:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4722:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4723:          }else{
1.251     brouard  4724:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4725:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4726:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4727:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4728:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4729:          }
                   4730:        }
                   4731:        printf( "**********\n#");
                   4732:        fprintf(ficresp, "**********\n#");
                   4733:        fprintf(ficresphtm, "**********</h3>\n");
                   4734:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4735:        fprintf(ficlog, "**********\n");
                   4736:       }
1.284     brouard  4737:       /*
                   4738:        Printing means of quantitative variables if any
                   4739:       */
                   4740:       for (z1=1; z1<= nqfveff; z1++) {
1.285     brouard  4741:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.0f individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.284     brouard  4742:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
                   4743:        if(weightopt==1){
                   4744:          printf(" Weighted mean and standard deviation of");
                   4745:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4746:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4747:        }
1.285     brouard  4748:        printf(" fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4749:        fprintf(ficlog," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4750:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
1.284     brouard  4751:       }
                   4752:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4753:       /*       for(m=1;m<=lastpass;m++){ */
                   4754:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4755:       /*   } */
                   4756:       /* } */
1.283     brouard  4757: 
1.251     brouard  4758:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4759:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4760:         fprintf(ficresp, " Age");
                   4761:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4762:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4763:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4764:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4765:       }
1.265     brouard  4766:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4767:       fprintf(ficresphtm, "\n");
                   4768:       
                   4769:       /* Header of frequency table by age */
                   4770:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4771:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4772:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4773:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4774:          if(s2!=0 && m!=0)
                   4775:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4776:        }
1.226     brouard  4777:       }
1.251     brouard  4778:       fprintf(ficresphtmfr, "\n");
                   4779:     
                   4780:       /* For each age */
                   4781:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4782:        fprintf(ficresphtm,"<tr>");
                   4783:        if(iage==iagemax+1){
                   4784:          fprintf(ficlog,"1");
                   4785:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4786:        }else if(iage==iagemax+2){
                   4787:          fprintf(ficlog,"0");
                   4788:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4789:        }else if(iage==iagemax+3){
                   4790:          fprintf(ficlog,"Total");
                   4791:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4792:        }else{
1.240     brouard  4793:          if(first==1){
1.251     brouard  4794:            first=0;
                   4795:            printf("See log file for details...\n");
                   4796:          }
                   4797:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4798:          fprintf(ficlog,"Age %d", iage);
                   4799:        }
1.265     brouard  4800:        for(s1=1; s1 <=nlstate ; s1++){
                   4801:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4802:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4803:        }
1.265     brouard  4804:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4805:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4806:            pos += freq[s1][m][iage];
                   4807:          if(pp[s1]>=1.e-10){
1.251     brouard  4808:            if(first==1){
1.265     brouard  4809:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4810:            }
1.265     brouard  4811:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4812:          }else{
                   4813:            if(first==1)
1.265     brouard  4814:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4815:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4816:          }
                   4817:        }
                   4818:       
1.265     brouard  4819:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4820:          /* posprop[s1]=0; */
                   4821:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4822:            pp[s1] += freq[s1][m][iage];
                   4823:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4824:       
                   4825:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4826:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4827:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4828:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4829:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4830:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4831:        }
                   4832:        
                   4833:        /* Writing ficresp */
                   4834:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4835:           if( iage <= iagemax){
                   4836:            fprintf(ficresp," %d",iage);
                   4837:           }
                   4838:         }else if( nj==2){
                   4839:           if( iage <= iagemax){
                   4840:            fprintf(ficresp," %d",iage);
                   4841:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4842:           }
1.240     brouard  4843:        }
1.265     brouard  4844:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4845:          if(pos>=1.e-5){
1.251     brouard  4846:            if(first==1)
1.265     brouard  4847:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4848:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4849:          }else{
                   4850:            if(first==1)
1.265     brouard  4851:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4852:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4853:          }
                   4854:          if( iage <= iagemax){
                   4855:            if(pos>=1.e-5){
1.265     brouard  4856:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4857:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4858:               }else if( nj==2){
                   4859:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4860:               }
                   4861:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4862:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4863:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4864:            } else{
                   4865:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4866:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4867:            }
1.240     brouard  4868:          }
1.265     brouard  4869:          pospropt[s1] +=posprop[s1];
                   4870:        } /* end loop s1 */
1.251     brouard  4871:        /* pospropt=0.; */
1.265     brouard  4872:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4873:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4874:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4875:              if(first==1){
1.265     brouard  4876:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4877:              }
1.265     brouard  4878:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4879:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4880:            }
1.265     brouard  4881:            if(s1!=0 && m!=0)
                   4882:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4883:          }
1.265     brouard  4884:        } /* end loop s1 */
1.251     brouard  4885:        posproptt=0.; 
1.265     brouard  4886:        for(s1=1; s1 <=nlstate; s1++){
                   4887:          posproptt += pospropt[s1];
1.251     brouard  4888:        }
                   4889:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4890:        fprintf(ficresphtm,"</tr>\n");
                   4891:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4892:          if(iage <= iagemax)
                   4893:            fprintf(ficresp,"\n");
1.240     brouard  4894:        }
1.251     brouard  4895:        if(first==1)
                   4896:          printf("Others in log...\n");
                   4897:        fprintf(ficlog,"\n");
                   4898:       } /* end loop age iage */
1.265     brouard  4899:       
1.251     brouard  4900:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4901:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4902:        if(posproptt < 1.e-5){
1.265     brouard  4903:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4904:        }else{
1.265     brouard  4905:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4906:        }
1.226     brouard  4907:       }
1.251     brouard  4908:       fprintf(ficresphtm,"</tr>\n");
                   4909:       fprintf(ficresphtm,"</table>\n");
                   4910:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4911:       if(posproptt < 1.e-5){
1.251     brouard  4912:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4913:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4914:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4915:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4916:        invalidvarcomb[j1]=1;
1.226     brouard  4917:       }else{
1.251     brouard  4918:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4919:        invalidvarcomb[j1]=0;
1.226     brouard  4920:       }
1.251     brouard  4921:       fprintf(ficresphtmfr,"</table>\n");
                   4922:       fprintf(ficlog,"\n");
                   4923:       if(j!=0){
                   4924:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4925:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4926:          for(k=1; k <=(nlstate+ndeath); k++){
                   4927:            if (k != i) {
1.265     brouard  4928:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4929:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4930:                  if(j1==1){ /* All dummy covariates to zero */
                   4931:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4932:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4933:                    printf("%d%d ",i,k);
                   4934:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4935:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4936:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4937:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4938:                  }
1.253     brouard  4939:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4940:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4941:                    x[iage]= (double)iage;
                   4942:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4943:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4944:                  }
1.268     brouard  4945:                  /* Some are not finite, but linreg will ignore these ages */
                   4946:                  no=0;
1.253     brouard  4947:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4948:                  pstart[s1]=b;
                   4949:                  pstart[s1-1]=a;
1.252     brouard  4950:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4951:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4952:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4953:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4954:                  printf("%d%d ",i,k);
                   4955:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4956:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4957:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4958:                  ;
                   4959:                }
                   4960:                /* printf("%12.7f )", param[i][jj][k]); */
                   4961:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4962:                s1++; 
1.251     brouard  4963:              } /* end jj */
                   4964:            } /* end k!= i */
                   4965:          } /* end k */
1.265     brouard  4966:        } /* end i, s1 */
1.251     brouard  4967:       } /* end j !=0 */
                   4968:     } /* end selected combination of covariate j1 */
                   4969:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4970:       printf("#Freqsummary: Starting values for the constants:\n");
                   4971:       fprintf(ficlog,"\n");
1.265     brouard  4972:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4973:        for(k=1; k <=(nlstate+ndeath); k++){
                   4974:          if (k != i) {
                   4975:            printf("%d%d ",i,k);
                   4976:            fprintf(ficlog,"%d%d ",i,k);
                   4977:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4978:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4979:              if(jj==1){ /* Age has to be done */
1.265     brouard  4980:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4981:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4982:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4983:              }
                   4984:              /* printf("%12.7f )", param[i][jj][k]); */
                   4985:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4986:              s1++; 
1.250     brouard  4987:            }
1.251     brouard  4988:            printf("\n");
                   4989:            fprintf(ficlog,"\n");
1.250     brouard  4990:          }
                   4991:        }
1.284     brouard  4992:       } /* end of state i */
1.251     brouard  4993:       printf("#Freqsummary\n");
                   4994:       fprintf(ficlog,"\n");
1.265     brouard  4995:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   4996:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   4997:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   4998:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   4999:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5000:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   5001:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   5002:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  5003:          /* } */
                   5004:        }
1.265     brouard  5005:       } /* end loop s1 */
1.251     brouard  5006:       
                   5007:       printf("\n");
                   5008:       fprintf(ficlog,"\n");
                   5009:     } /* end j=0 */
1.249     brouard  5010:   } /* end j */
1.252     brouard  5011: 
1.253     brouard  5012:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  5013:     for(i=1, jk=1; i <=nlstate; i++){
                   5014:       for(j=1; j <=nlstate+ndeath; j++){
                   5015:        if(j!=i){
                   5016:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   5017:          printf("%1d%1d",i,j);
                   5018:          fprintf(ficparo,"%1d%1d",i,j);
                   5019:          for(k=1; k<=ncovmodel;k++){
                   5020:            /*    printf(" %lf",param[i][j][k]); */
                   5021:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   5022:            p[jk]=pstart[jk];
                   5023:            printf(" %f ",pstart[jk]);
                   5024:            fprintf(ficparo," %f ",pstart[jk]);
                   5025:            jk++;
                   5026:          }
                   5027:          printf("\n");
                   5028:          fprintf(ficparo,"\n");
                   5029:        }
                   5030:       }
                   5031:     }
                   5032:   } /* end mle=-2 */
1.226     brouard  5033:   dateintmean=dateintsum/k2cpt; 
1.296     brouard  5034:   date2dmy(dateintmean,&jintmean,&mintmean,&aintmean);
1.240     brouard  5035:   
1.226     brouard  5036:   fclose(ficresp);
                   5037:   fclose(ficresphtm);
                   5038:   fclose(ficresphtmfr);
1.283     brouard  5039:   free_vector(idq,1,nqfveff);
1.226     brouard  5040:   free_vector(meanq,1,nqfveff);
1.284     brouard  5041:   free_vector(stdq,1,nqfveff);
1.226     brouard  5042:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  5043:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   5044:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  5045:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5046:   free_vector(pospropt,1,nlstate);
                   5047:   free_vector(posprop,1,nlstate);
1.251     brouard  5048:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5049:   free_vector(pp,1,nlstate);
                   5050:   /* End of freqsummary */
                   5051: }
1.126     brouard  5052: 
1.268     brouard  5053: /* Simple linear regression */
                   5054: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   5055: 
                   5056:   /* y=a+bx regression */
                   5057:   double   sumx = 0.0;                        /* sum of x                      */
                   5058:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   5059:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   5060:   double   sumy = 0.0;                        /* sum of y                      */
                   5061:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   5062:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   5063:   double yhat;
                   5064:   
                   5065:   double denom=0;
                   5066:   int i;
                   5067:   int ne=*no;
                   5068:   
                   5069:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5070:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5071:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5072:       continue;
                   5073:     }
                   5074:     ne=ne+1;
                   5075:     sumx  += x[i];       
                   5076:     sumx2 += x[i]*x[i];  
                   5077:     sumxy += x[i] * y[i];
                   5078:     sumy  += y[i];      
                   5079:     sumy2 += y[i]*y[i]; 
                   5080:     denom = (ne * sumx2 - sumx*sumx);
                   5081:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5082:   } 
                   5083:   
                   5084:   denom = (ne * sumx2 - sumx*sumx);
                   5085:   if (denom == 0) {
                   5086:     // vertical, slope m is infinity
                   5087:     *b = INFINITY;
                   5088:     *a = 0;
                   5089:     if (r) *r = 0;
                   5090:     return 1;
                   5091:   }
                   5092:   
                   5093:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5094:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5095:   if (r!=NULL) {
                   5096:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5097:       sqrt((sumx2 - sumx*sumx/ne) *
                   5098:           (sumy2 - sumy*sumy/ne));
                   5099:   }
                   5100:   *no=ne;
                   5101:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5102:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5103:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5104:       continue;
                   5105:     }
                   5106:     ne=ne+1;
                   5107:     yhat = y[i] - *a -*b* x[i];
                   5108:     sume2  += yhat * yhat ;       
                   5109:     
                   5110:     denom = (ne * sumx2 - sumx*sumx);
                   5111:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5112:   } 
                   5113:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5114:   *sa= *sb * sqrt(sumx2/ne);
                   5115:   
                   5116:   return 0; 
                   5117: }
                   5118: 
1.126     brouard  5119: /************ Prevalence ********************/
1.227     brouard  5120: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5121: {  
                   5122:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5123:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5124:      We still use firstpass and lastpass as another selection.
                   5125:   */
1.126     brouard  5126:  
1.227     brouard  5127:   int i, m, jk, j1, bool, z1,j, iv;
                   5128:   int mi; /* Effective wave */
                   5129:   int iage;
                   5130:   double agebegin, ageend;
                   5131: 
                   5132:   double **prop;
                   5133:   double posprop; 
                   5134:   double  y2; /* in fractional years */
                   5135:   int iagemin, iagemax;
                   5136:   int first; /** to stop verbosity which is redirected to log file */
                   5137: 
                   5138:   iagemin= (int) agemin;
                   5139:   iagemax= (int) agemax;
                   5140:   /*pp=vector(1,nlstate);*/
1.251     brouard  5141:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5142:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5143:   j1=0;
1.222     brouard  5144:   
1.227     brouard  5145:   /*j=cptcoveff;*/
                   5146:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5147:   
1.288     brouard  5148:   first=0;
1.227     brouard  5149:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5150:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5151:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5152:        prop[i][iage]=0.0;
                   5153:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5154:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5155:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5156:     
                   5157:     for (i=1; i<=imx; i++) { /* Each individual */
                   5158:       bool=1;
                   5159:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5160:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5161:        m=mw[mi][i];
                   5162:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5163:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5164:        for (z1=1; z1<=cptcoveff; z1++){
                   5165:          if( Fixed[Tmodelind[z1]]==1){
                   5166:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5167:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5168:              bool=0;
                   5169:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5170:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5171:              bool=0;
                   5172:            }
                   5173:        }
                   5174:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5175:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5176:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5177:          if(m >=firstpass && m <=lastpass){
                   5178:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5179:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5180:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5181:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5182:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5183:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5184:                exit(1);
                   5185:              }
                   5186:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5187:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5188:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5189:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5190:              } /* end valid statuses */ 
                   5191:            } /* end selection of dates */
                   5192:          } /* end selection of waves */
                   5193:        } /* end bool */
                   5194:       } /* end wave */
                   5195:     } /* end individual */
                   5196:     for(i=iagemin; i <= iagemax+3; i++){  
                   5197:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5198:        posprop += prop[jk][i]; 
                   5199:       } 
                   5200:       
                   5201:       for(jk=1; jk <=nlstate ; jk++){      
                   5202:        if( i <=  iagemax){ 
                   5203:          if(posprop>=1.e-5){ 
                   5204:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5205:          } else{
1.288     brouard  5206:            if(!first){
                   5207:              first=1;
1.266     brouard  5208:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5209:            }else{
1.288     brouard  5210:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5211:            }
                   5212:          }
                   5213:        } 
                   5214:       }/* end jk */ 
                   5215:     }/* end i */ 
1.222     brouard  5216:      /*} *//* end i1 */
1.227     brouard  5217:   } /* end j1 */
1.222     brouard  5218:   
1.227     brouard  5219:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5220:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5221:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5222: }  /* End of prevalence */
1.126     brouard  5223: 
                   5224: /************* Waves Concatenation ***************/
                   5225: 
                   5226: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5227: {
1.298     brouard  5228:   /* Concatenates waves: wav[i] is the number of effective (useful waves in the sense that a non interview is useless) of individual i.
1.126     brouard  5229:      Death is a valid wave (if date is known).
                   5230:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5231:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
1.298     brouard  5232:      and mw[mi+1][i]. dh depends on stepm. s[m][i] exists for any wave from firstpass to lastpass
1.227     brouard  5233:   */
1.126     brouard  5234: 
1.224     brouard  5235:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5236:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5237:      double sum=0., jmean=0.;*/
1.224     brouard  5238:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5239:   int j, k=0,jk, ju, jl;
                   5240:   double sum=0.;
                   5241:   first=0;
1.214     brouard  5242:   firstwo=0;
1.217     brouard  5243:   firsthree=0;
1.218     brouard  5244:   firstfour=0;
1.164     brouard  5245:   jmin=100000;
1.126     brouard  5246:   jmax=-1;
                   5247:   jmean=0.;
1.224     brouard  5248: 
                   5249: /* Treating live states */
1.214     brouard  5250:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5251:     mi=0;  /* First valid wave */
1.227     brouard  5252:     mli=0; /* Last valid wave */
1.126     brouard  5253:     m=firstpass;
1.214     brouard  5254:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5255:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5256:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5257:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5258:        mw[++mi][i]=m;
                   5259:        mli=m;
1.224     brouard  5260:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5261:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5262:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5263:       }
1.227     brouard  5264:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5265: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5266:        break;
1.224     brouard  5267: #else
1.227     brouard  5268:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5269:          if(firsthree == 0){
1.302     brouard  5270:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5271:            firsthree=1;
                   5272:          }
1.302     brouard  5273:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5274:          mw[++mi][i]=m;
                   5275:          mli=m;
                   5276:        }
                   5277:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5278:          nbwarn++;
                   5279:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5280:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5281:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5282:          }
                   5283:          break;
                   5284:        }
                   5285:        break;
1.224     brouard  5286: #endif
1.227     brouard  5287:       }/* End m >= lastpass */
1.126     brouard  5288:     }/* end while */
1.224     brouard  5289: 
1.227     brouard  5290:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5291:     /* After last pass */
1.224     brouard  5292: /* Treating death states */
1.214     brouard  5293:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5294:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5295:       /* } */
1.126     brouard  5296:       mi++;    /* Death is another wave */
                   5297:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5298:       /* Only death is a correct wave */
1.126     brouard  5299:       mw[mi][i]=m;
1.257     brouard  5300:     } /* else not in a death state */
1.224     brouard  5301: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5302:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5303:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5304:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5305:          nbwarn++;
                   5306:          if(firstfiv==0){
                   5307:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5308:            firstfiv=1;
                   5309:          }else{
                   5310:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5311:          }
                   5312:        }else{ /* Death occured afer last wave potential bias */
                   5313:          nberr++;
                   5314:          if(firstwo==0){
1.257     brouard  5315:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5316:            firstwo=1;
                   5317:          }
1.257     brouard  5318:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5319:        }
1.257     brouard  5320:       }else{ /* if date of interview is unknown */
1.227     brouard  5321:        /* death is known but not confirmed by death status at any wave */
                   5322:        if(firstfour==0){
                   5323:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5324:          firstfour=1;
                   5325:        }
                   5326:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5327:       }
1.224     brouard  5328:     } /* end if date of death is known */
                   5329: #endif
                   5330:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5331:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5332:     if(mi==0){
                   5333:       nbwarn++;
                   5334:       if(first==0){
1.227     brouard  5335:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5336:        first=1;
1.126     brouard  5337:       }
                   5338:       if(first==1){
1.227     brouard  5339:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5340:       }
                   5341:     } /* end mi==0 */
                   5342:   } /* End individuals */
1.214     brouard  5343:   /* wav and mw are no more changed */
1.223     brouard  5344:        
1.214     brouard  5345:   
1.126     brouard  5346:   for(i=1; i<=imx; i++){
                   5347:     for(mi=1; mi<wav[i];mi++){
                   5348:       if (stepm <=0)
1.227     brouard  5349:        dh[mi][i]=1;
1.126     brouard  5350:       else{
1.260     brouard  5351:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5352:          if (agedc[i] < 2*AGESUP) {
                   5353:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5354:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5355:            else if(j<0){
                   5356:              nberr++;
                   5357:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5358:              j=1; /* Temporary Dangerous patch */
                   5359:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5360:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5361:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5362:            }
                   5363:            k=k+1;
                   5364:            if (j >= jmax){
                   5365:              jmax=j;
                   5366:              ijmax=i;
                   5367:            }
                   5368:            if (j <= jmin){
                   5369:              jmin=j;
                   5370:              ijmin=i;
                   5371:            }
                   5372:            sum=sum+j;
                   5373:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5374:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5375:          }
                   5376:        }
                   5377:        else{
                   5378:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5379: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5380:                                        
1.227     brouard  5381:          k=k+1;
                   5382:          if (j >= jmax) {
                   5383:            jmax=j;
                   5384:            ijmax=i;
                   5385:          }
                   5386:          else if (j <= jmin){
                   5387:            jmin=j;
                   5388:            ijmin=i;
                   5389:          }
                   5390:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5391:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5392:          if(j<0){
                   5393:            nberr++;
                   5394:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5395:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5396:          }
                   5397:          sum=sum+j;
                   5398:        }
                   5399:        jk= j/stepm;
                   5400:        jl= j -jk*stepm;
                   5401:        ju= j -(jk+1)*stepm;
                   5402:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5403:          if(jl==0){
                   5404:            dh[mi][i]=jk;
                   5405:            bh[mi][i]=0;
                   5406:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5407:                  * to avoid the price of an extra matrix product in likelihood */
                   5408:            dh[mi][i]=jk+1;
                   5409:            bh[mi][i]=ju;
                   5410:          }
                   5411:        }else{
                   5412:          if(jl <= -ju){
                   5413:            dh[mi][i]=jk;
                   5414:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5415:                                 * is higher than the multiple of stepm and negative otherwise.
                   5416:                                 */
                   5417:          }
                   5418:          else{
                   5419:            dh[mi][i]=jk+1;
                   5420:            bh[mi][i]=ju;
                   5421:          }
                   5422:          if(dh[mi][i]==0){
                   5423:            dh[mi][i]=1; /* At least one step */
                   5424:            bh[mi][i]=ju; /* At least one step */
                   5425:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5426:          }
                   5427:        } /* end if mle */
1.126     brouard  5428:       }
                   5429:     } /* end wave */
                   5430:   }
                   5431:   jmean=sum/k;
                   5432:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5433:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5434: }
1.126     brouard  5435: 
                   5436: /*********** Tricode ****************************/
1.220     brouard  5437:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5438:  {
                   5439:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5440:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5441:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5442:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5443:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5444:     */
1.130     brouard  5445: 
1.242     brouard  5446:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5447:    int modmaxcovj=0; /* Modality max of covariates j */
                   5448:    int cptcode=0; /* Modality max of covariates j */
                   5449:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5450: 
                   5451: 
1.242     brouard  5452:    /* cptcoveff=0;  */
                   5453:    /* *cptcov=0; */
1.126     brouard  5454:  
1.242     brouard  5455:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5456:    for (k=1; k <= maxncov; k++)
                   5457:      for(j=1; j<=2; j++)
                   5458:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5459: 
1.242     brouard  5460:    /* Loop on covariates without age and products and no quantitative variable */
                   5461:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5462:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5463:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5464:        switch(Fixed[k]) {
                   5465:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5466:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5467:           ij=(int)(covar[Tvar[k]][i]);
                   5468:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5469:            * If product of Vn*Vm, still boolean *:
                   5470:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5471:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5472:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5473:              modality of the nth covariate of individual i. */
                   5474:           if (ij > modmaxcovj)
                   5475:             modmaxcovj=ij; 
                   5476:           else if (ij < modmincovj) 
                   5477:             modmincovj=ij; 
1.287     brouard  5478:           if (ij <0 || ij >1 ){
                   5479:             printf("Information, IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5480:             fprintf(ficlog,"Information, currently IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5481:           }
                   5482:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5483:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5484:             exit(1);
                   5485:           }else
                   5486:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5487:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5488:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5489:           /* getting the maximum value of the modality of the covariate
                   5490:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5491:              female ies 1, then modmaxcovj=1.
                   5492:           */
                   5493:         } /* end for loop on individuals i */
                   5494:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5495:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5496:         cptcode=modmaxcovj;
                   5497:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5498:         /*for (i=0; i<=cptcode; i++) {*/
                   5499:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5500:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5501:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5502:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5503:             if( j != -1){
                   5504:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5505:                                  covariate for which somebody answered excluding 
                   5506:                                  undefined. Usually 2: 0 and 1. */
                   5507:             }
                   5508:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5509:                                     covariate for which somebody answered including 
                   5510:                                     undefined. Usually 3: -1, 0 and 1. */
                   5511:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5512:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5513:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5514:                        
1.242     brouard  5515:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5516:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5517:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5518:         /* modmincovj=3; modmaxcovj = 7; */
                   5519:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5520:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5521:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5522:         /* nbcode[Tvar[j]][ij]=k; */
                   5523:         /* nbcode[Tvar[j]][1]=0; */
                   5524:         /* nbcode[Tvar[j]][2]=1; */
                   5525:         /* nbcode[Tvar[j]][3]=2; */
                   5526:         /* To be continued (not working yet). */
                   5527:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5528: 
                   5529:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5530:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5531:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5532:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5533:         /*, could be restored in the future */
                   5534:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5535:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5536:             break;
                   5537:           }
                   5538:           ij++;
1.287     brouard  5539:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5540:           cptcode = ij; /* New max modality for covar j */
                   5541:         } /* end of loop on modality i=-1 to 1 or more */
                   5542:         break;
                   5543:        case 1: /* Testing on varying covariate, could be simple and
                   5544:                * should look at waves or product of fixed *
                   5545:                * varying. No time to test -1, assuming 0 and 1 only */
                   5546:         ij=0;
                   5547:         for(i=0; i<=1;i++){
                   5548:           nbcode[Tvar[k]][++ij]=i;
                   5549:         }
                   5550:         break;
                   5551:        default:
                   5552:         break;
                   5553:        } /* end switch */
                   5554:      } /* end dummy test */
1.287     brouard  5555:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5556:   
                   5557:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5558:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5559:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5560:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5561:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5562:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5563:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5564:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5565:   
                   5566:    ij=0;
                   5567:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5568:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5569:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5570:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5571:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5572:        /* If product not in single variable we don't print results */
                   5573:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5574:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5575:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5576:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5577:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5578:        if(Fixed[k]!=0)
                   5579:         anyvaryingduminmodel=1;
                   5580:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5581:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5582:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5583:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5584:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5585:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5586:      } 
                   5587:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5588:    /* ij--; */
                   5589:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5590:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5591:                * because they can be excluded from the model and real
                   5592:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5593:    for(j=ij+1; j<= cptcovt; j++){
                   5594:      Tvaraff[j]=0;
                   5595:      Tmodelind[j]=0;
                   5596:    }
                   5597:    for(j=ntveff+1; j<= cptcovt; j++){
                   5598:      TmodelInvind[j]=0;
                   5599:    }
                   5600:    /* To be sorted */
                   5601:    ;
                   5602:  }
1.126     brouard  5603: 
1.145     brouard  5604: 
1.126     brouard  5605: /*********** Health Expectancies ****************/
                   5606: 
1.235     brouard  5607:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5608: 
                   5609: {
                   5610:   /* Health expectancies, no variances */
1.164     brouard  5611:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5612:   int nhstepma, nstepma; /* Decreasing with age */
                   5613:   double age, agelim, hf;
                   5614:   double ***p3mat;
                   5615:   double eip;
                   5616: 
1.238     brouard  5617:   /* pstamp(ficreseij); */
1.126     brouard  5618:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5619:   fprintf(ficreseij,"# Age");
                   5620:   for(i=1; i<=nlstate;i++){
                   5621:     for(j=1; j<=nlstate;j++){
                   5622:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5623:     }
                   5624:     fprintf(ficreseij," e%1d. ",i);
                   5625:   }
                   5626:   fprintf(ficreseij,"\n");
                   5627: 
                   5628:   
                   5629:   if(estepm < stepm){
                   5630:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5631:   }
                   5632:   else  hstepm=estepm;   
                   5633:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5634:    * This is mainly to measure the difference between two models: for example
                   5635:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5636:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5637:    * progression in between and thus overestimating or underestimating according
                   5638:    * to the curvature of the survival function. If, for the same date, we 
                   5639:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5640:    * to compare the new estimate of Life expectancy with the same linear 
                   5641:    * hypothesis. A more precise result, taking into account a more precise
                   5642:    * curvature will be obtained if estepm is as small as stepm. */
                   5643: 
                   5644:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5645:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5646:      nhstepm is the number of hstepm from age to agelim 
                   5647:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5648:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5649:      and note for a fixed period like estepm months */
                   5650:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5651:      survival function given by stepm (the optimization length). Unfortunately it
                   5652:      means that if the survival funtion is printed only each two years of age and if
                   5653:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5654:      results. So we changed our mind and took the option of the best precision.
                   5655:   */
                   5656:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5657: 
                   5658:   agelim=AGESUP;
                   5659:   /* If stepm=6 months */
                   5660:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5661:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5662:     
                   5663: /* nhstepm age range expressed in number of stepm */
                   5664:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5665:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5666:   /* if (stepm >= YEARM) hstepm=1;*/
                   5667:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5668:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5669: 
                   5670:   for (age=bage; age<=fage; age ++){ 
                   5671:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5672:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5673:     /* if (stepm >= YEARM) hstepm=1;*/
                   5674:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5675: 
                   5676:     /* If stepm=6 months */
                   5677:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5678:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5679:     
1.235     brouard  5680:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5681:     
                   5682:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5683:     
                   5684:     printf("%d|",(int)age);fflush(stdout);
                   5685:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5686:     
                   5687:     /* Computing expectancies */
                   5688:     for(i=1; i<=nlstate;i++)
                   5689:       for(j=1; j<=nlstate;j++)
                   5690:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5691:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5692:          
                   5693:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5694: 
                   5695:        }
                   5696: 
                   5697:     fprintf(ficreseij,"%3.0f",age );
                   5698:     for(i=1; i<=nlstate;i++){
                   5699:       eip=0;
                   5700:       for(j=1; j<=nlstate;j++){
                   5701:        eip +=eij[i][j][(int)age];
                   5702:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5703:       }
                   5704:       fprintf(ficreseij,"%9.4f", eip );
                   5705:     }
                   5706:     fprintf(ficreseij,"\n");
                   5707:     
                   5708:   }
                   5709:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5710:   printf("\n");
                   5711:   fprintf(ficlog,"\n");
                   5712:   
                   5713: }
                   5714: 
1.235     brouard  5715:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5716: 
                   5717: {
                   5718:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5719:      to initial status i, ei. .
1.126     brouard  5720:   */
                   5721:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5722:   int nhstepma, nstepma; /* Decreasing with age */
                   5723:   double age, agelim, hf;
                   5724:   double ***p3matp, ***p3matm, ***varhe;
                   5725:   double **dnewm,**doldm;
                   5726:   double *xp, *xm;
                   5727:   double **gp, **gm;
                   5728:   double ***gradg, ***trgradg;
                   5729:   int theta;
                   5730: 
                   5731:   double eip, vip;
                   5732: 
                   5733:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5734:   xp=vector(1,npar);
                   5735:   xm=vector(1,npar);
                   5736:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5737:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5738:   
                   5739:   pstamp(ficresstdeij);
                   5740:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5741:   fprintf(ficresstdeij,"# Age");
                   5742:   for(i=1; i<=nlstate;i++){
                   5743:     for(j=1; j<=nlstate;j++)
                   5744:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5745:     fprintf(ficresstdeij," e%1d. ",i);
                   5746:   }
                   5747:   fprintf(ficresstdeij,"\n");
                   5748: 
                   5749:   pstamp(ficrescveij);
                   5750:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5751:   fprintf(ficrescveij,"# Age");
                   5752:   for(i=1; i<=nlstate;i++)
                   5753:     for(j=1; j<=nlstate;j++){
                   5754:       cptj= (j-1)*nlstate+i;
                   5755:       for(i2=1; i2<=nlstate;i2++)
                   5756:        for(j2=1; j2<=nlstate;j2++){
                   5757:          cptj2= (j2-1)*nlstate+i2;
                   5758:          if(cptj2 <= cptj)
                   5759:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5760:        }
                   5761:     }
                   5762:   fprintf(ficrescveij,"\n");
                   5763:   
                   5764:   if(estepm < stepm){
                   5765:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5766:   }
                   5767:   else  hstepm=estepm;   
                   5768:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5769:    * This is mainly to measure the difference between two models: for example
                   5770:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5771:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5772:    * progression in between and thus overestimating or underestimating according
                   5773:    * to the curvature of the survival function. If, for the same date, we 
                   5774:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5775:    * to compare the new estimate of Life expectancy with the same linear 
                   5776:    * hypothesis. A more precise result, taking into account a more precise
                   5777:    * curvature will be obtained if estepm is as small as stepm. */
                   5778: 
                   5779:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5780:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5781:      nhstepm is the number of hstepm from age to agelim 
                   5782:      nstepm is the number of stepm from age to agelin. 
                   5783:      Look at hpijx to understand the reason of that which relies in memory size
                   5784:      and note for a fixed period like estepm months */
                   5785:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5786:      survival function given by stepm (the optimization length). Unfortunately it
                   5787:      means that if the survival funtion is printed only each two years of age and if
                   5788:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5789:      results. So we changed our mind and took the option of the best precision.
                   5790:   */
                   5791:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5792: 
                   5793:   /* If stepm=6 months */
                   5794:   /* nhstepm age range expressed in number of stepm */
                   5795:   agelim=AGESUP;
                   5796:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5797:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5798:   /* if (stepm >= YEARM) hstepm=1;*/
                   5799:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5800:   
                   5801:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5802:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5803:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5804:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5805:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5806:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5807: 
                   5808:   for (age=bage; age<=fage; age ++){ 
                   5809:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5810:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5811:     /* if (stepm >= YEARM) hstepm=1;*/
                   5812:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5813:                
1.126     brouard  5814:     /* If stepm=6 months */
                   5815:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5816:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5817:     
                   5818:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5819:                
1.126     brouard  5820:     /* Computing  Variances of health expectancies */
                   5821:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5822:        decrease memory allocation */
                   5823:     for(theta=1; theta <=npar; theta++){
                   5824:       for(i=1; i<=npar; i++){ 
1.222     brouard  5825:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5826:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5827:       }
1.235     brouard  5828:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5829:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5830:                        
1.126     brouard  5831:       for(j=1; j<= nlstate; j++){
1.222     brouard  5832:        for(i=1; i<=nlstate; i++){
                   5833:          for(h=0; h<=nhstepm-1; h++){
                   5834:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5835:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5836:          }
                   5837:        }
1.126     brouard  5838:       }
1.218     brouard  5839:                        
1.126     brouard  5840:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5841:        for(h=0; h<=nhstepm-1; h++){
                   5842:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5843:        }
1.126     brouard  5844:     }/* End theta */
                   5845:     
                   5846:     
                   5847:     for(h=0; h<=nhstepm-1; h++)
                   5848:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5849:        for(theta=1; theta <=npar; theta++)
                   5850:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5851:     
1.218     brouard  5852:                
1.222     brouard  5853:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5854:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5855:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5856:                
1.222     brouard  5857:     printf("%d|",(int)age);fflush(stdout);
                   5858:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5859:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5860:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5861:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5862:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5863:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5864:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5865:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5866:       }
                   5867:     }
1.218     brouard  5868:                
1.126     brouard  5869:     /* Computing expectancies */
1.235     brouard  5870:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5871:     for(i=1; i<=nlstate;i++)
                   5872:       for(j=1; j<=nlstate;j++)
1.222     brouard  5873:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5874:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5875:                                        
1.222     brouard  5876:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5877:                                        
1.222     brouard  5878:        }
1.269     brouard  5879: 
                   5880:     /* Standard deviation of expectancies ij */                
1.126     brouard  5881:     fprintf(ficresstdeij,"%3.0f",age );
                   5882:     for(i=1; i<=nlstate;i++){
                   5883:       eip=0.;
                   5884:       vip=0.;
                   5885:       for(j=1; j<=nlstate;j++){
1.222     brouard  5886:        eip += eij[i][j][(int)age];
                   5887:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5888:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5889:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5890:       }
                   5891:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5892:     }
                   5893:     fprintf(ficresstdeij,"\n");
1.218     brouard  5894:                
1.269     brouard  5895:     /* Variance of expectancies ij */          
1.126     brouard  5896:     fprintf(ficrescveij,"%3.0f",age );
                   5897:     for(i=1; i<=nlstate;i++)
                   5898:       for(j=1; j<=nlstate;j++){
1.222     brouard  5899:        cptj= (j-1)*nlstate+i;
                   5900:        for(i2=1; i2<=nlstate;i2++)
                   5901:          for(j2=1; j2<=nlstate;j2++){
                   5902:            cptj2= (j2-1)*nlstate+i2;
                   5903:            if(cptj2 <= cptj)
                   5904:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5905:          }
1.126     brouard  5906:       }
                   5907:     fprintf(ficrescveij,"\n");
1.218     brouard  5908:                
1.126     brouard  5909:   }
                   5910:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5911:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5912:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5913:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5914:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5915:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5916:   printf("\n");
                   5917:   fprintf(ficlog,"\n");
1.218     brouard  5918:        
1.126     brouard  5919:   free_vector(xm,1,npar);
                   5920:   free_vector(xp,1,npar);
                   5921:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5922:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5923:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5924: }
1.218     brouard  5925:  
1.126     brouard  5926: /************ Variance ******************/
1.235     brouard  5927:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5928:  {
1.279     brouard  5929:    /** Variance of health expectancies 
                   5930:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5931:     * double **newm;
                   5932:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5933:     */
1.218     brouard  5934:   
                   5935:    /* int movingaverage(); */
                   5936:    double **dnewm,**doldm;
                   5937:    double **dnewmp,**doldmp;
                   5938:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  5939:    int first=0;
1.218     brouard  5940:    int k;
                   5941:    double *xp;
1.279     brouard  5942:    double **gp, **gm;  /**< for var eij */
                   5943:    double ***gradg, ***trgradg; /**< for var eij */
                   5944:    double **gradgp, **trgradgp; /**< for var p point j */
                   5945:    double *gpp, *gmp; /**< for var p point j */
                   5946:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5947:    double ***p3mat;
                   5948:    double age,agelim, hf;
                   5949:    /* double ***mobaverage; */
                   5950:    int theta;
                   5951:    char digit[4];
                   5952:    char digitp[25];
                   5953: 
                   5954:    char fileresprobmorprev[FILENAMELENGTH];
                   5955: 
                   5956:    if(popbased==1){
                   5957:      if(mobilav!=0)
                   5958:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5959:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5960:    }
                   5961:    else 
                   5962:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5963: 
1.218     brouard  5964:    /* if (mobilav!=0) { */
                   5965:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5966:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5967:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5968:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5969:    /*   } */
                   5970:    /* } */
                   5971: 
                   5972:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5973:    sprintf(digit,"%-d",ij);
                   5974:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5975:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5976:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5977:    strcat(fileresprobmorprev,fileresu);
                   5978:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5979:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5980:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5981:    }
                   5982:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5983:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5984:    pstamp(ficresprobmorprev);
                   5985:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  5986:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   5987:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   5988:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   5989:    }
                   5990:    for(j=1;j<=cptcoveff;j++) 
                   5991:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   5992:    fprintf(ficresprobmorprev,"\n");
                   5993: 
1.218     brouard  5994:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   5995:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   5996:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   5997:      for(i=1; i<=nlstate;i++)
                   5998:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   5999:    }  
                   6000:    fprintf(ficresprobmorprev,"\n");
                   6001:   
                   6002:    fprintf(ficgp,"\n# Routine varevsij");
                   6003:    fprintf(ficgp,"\nunset title \n");
                   6004:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   6005:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   6006:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  6007: 
1.218     brouard  6008:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6009:    pstamp(ficresvij);
                   6010:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   6011:    if(popbased==1)
                   6012:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   6013:    else
                   6014:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   6015:    fprintf(ficresvij,"# Age");
                   6016:    for(i=1; i<=nlstate;i++)
                   6017:      for(j=1; j<=nlstate;j++)
                   6018:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   6019:    fprintf(ficresvij,"\n");
                   6020: 
                   6021:    xp=vector(1,npar);
                   6022:    dnewm=matrix(1,nlstate,1,npar);
                   6023:    doldm=matrix(1,nlstate,1,nlstate);
                   6024:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   6025:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6026: 
                   6027:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   6028:    gpp=vector(nlstate+1,nlstate+ndeath);
                   6029:    gmp=vector(nlstate+1,nlstate+ndeath);
                   6030:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  6031:   
1.218     brouard  6032:    if(estepm < stepm){
                   6033:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   6034:    }
                   6035:    else  hstepm=estepm;   
                   6036:    /* For example we decided to compute the life expectancy with the smallest unit */
                   6037:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6038:       nhstepm is the number of hstepm from age to agelim 
                   6039:       nstepm is the number of stepm from age to agelim. 
                   6040:       Look at function hpijx to understand why because of memory size limitations, 
                   6041:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   6042:       survival function given by stepm (the optimization length). Unfortunately it
                   6043:       means that if the survival funtion is printed every two years of age and if
                   6044:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6045:       results. So we changed our mind and took the option of the best precision.
                   6046:    */
                   6047:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6048:    agelim = AGESUP;
                   6049:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6050:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6051:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6052:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6053:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   6054:      gp=matrix(0,nhstepm,1,nlstate);
                   6055:      gm=matrix(0,nhstepm,1,nlstate);
                   6056:                
                   6057:                
                   6058:      for(theta=1; theta <=npar; theta++){
                   6059:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   6060:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6061:        }
1.279     brouard  6062:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   6063:        * returns into prlim .
1.288     brouard  6064:        */
1.242     brouard  6065:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  6066: 
                   6067:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6068:        if (popbased==1) {
                   6069:         if(mobilav ==0){
                   6070:           for(i=1; i<=nlstate;i++)
                   6071:             prlim[i][i]=probs[(int)age][i][ij];
                   6072:         }else{ /* mobilav */ 
                   6073:           for(i=1; i<=nlstate;i++)
                   6074:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6075:         }
                   6076:        }
1.295     brouard  6077:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}x\f$ at horizon h.
1.279     brouard  6078:        */                      
                   6079:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292     brouard  6080:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6081:        * at horizon h in state j including mortality.
                   6082:        */
1.218     brouard  6083:        for(j=1; j<= nlstate; j++){
                   6084:         for(h=0; h<=nhstepm; h++){
                   6085:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6086:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6087:         }
                   6088:        }
1.279     brouard  6089:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6090:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6091:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6092:        */
                   6093:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6094:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6095:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6096:        }
                   6097:        
                   6098:        /* Again with minus shift */
1.218     brouard  6099:                        
                   6100:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6101:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6102: 
1.242     brouard  6103:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6104:                        
                   6105:        if (popbased==1) {
                   6106:         if(mobilav ==0){
                   6107:           for(i=1; i<=nlstate;i++)
                   6108:             prlim[i][i]=probs[(int)age][i][ij];
                   6109:         }else{ /* mobilav */ 
                   6110:           for(i=1; i<=nlstate;i++)
                   6111:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6112:         }
                   6113:        }
                   6114:                        
1.235     brouard  6115:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6116:                        
                   6117:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6118:         for(h=0; h<=nhstepm; h++){
                   6119:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6120:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6121:         }
                   6122:        }
                   6123:        /* This for computing probability of death (h=1 means
                   6124:          computed over hstepm matrices product = hstepm*stepm months) 
                   6125:          as a weighted average of prlim.
                   6126:        */
                   6127:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6128:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6129:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6130:        }    
1.279     brouard  6131:        /* end shifting computations */
                   6132: 
                   6133:        /**< Computing gradient matrix at horizon h 
                   6134:        */
1.218     brouard  6135:        for(j=1; j<= nlstate; j++) /* vareij */
                   6136:         for(h=0; h<=nhstepm; h++){
                   6137:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6138:         }
1.279     brouard  6139:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6140:        */
                   6141:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6142:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6143:        }
                   6144:                        
                   6145:      } /* End theta */
1.279     brouard  6146:      
                   6147:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6148:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6149:                
                   6150:      for(h=0; h<=nhstepm; h++) /* veij */
                   6151:        for(j=1; j<=nlstate;j++)
                   6152:         for(theta=1; theta <=npar; theta++)
                   6153:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6154:                
                   6155:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6156:        for(theta=1; theta <=npar; theta++)
                   6157:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6158:      /**< as well as its transposed matrix 
                   6159:       */               
1.218     brouard  6160:                
                   6161:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6162:      for(i=1;i<=nlstate;i++)
                   6163:        for(j=1;j<=nlstate;j++)
                   6164:         vareij[i][j][(int)age] =0.;
1.279     brouard  6165: 
                   6166:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6167:       * and k (nhstepm) formula 15 of article
                   6168:       * Lievre-Brouard-Heathcote
                   6169:       */
                   6170:      
1.218     brouard  6171:      for(h=0;h<=nhstepm;h++){
                   6172:        for(k=0;k<=nhstepm;k++){
                   6173:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6174:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6175:         for(i=1;i<=nlstate;i++)
                   6176:           for(j=1;j<=nlstate;j++)
                   6177:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6178:        }
                   6179:      }
                   6180:                
1.279     brouard  6181:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6182:       * p.j overall mortality formula 49 but computed directly because
                   6183:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6184:       * wix is independent of theta.
                   6185:       */
1.218     brouard  6186:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6187:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6188:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6189:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6190:         varppt[j][i]=doldmp[j][i];
                   6191:      /* end ppptj */
                   6192:      /*  x centered again */
                   6193:                
1.242     brouard  6194:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6195:                
                   6196:      if (popbased==1) {
                   6197:        if(mobilav ==0){
                   6198:         for(i=1; i<=nlstate;i++)
                   6199:           prlim[i][i]=probs[(int)age][i][ij];
                   6200:        }else{ /* mobilav */ 
                   6201:         for(i=1; i<=nlstate;i++)
                   6202:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6203:        }
                   6204:      }
                   6205:                
                   6206:      /* This for computing probability of death (h=1 means
                   6207:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6208:        as a weighted average of prlim.
                   6209:      */
1.235     brouard  6210:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6211:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6212:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6213:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6214:      }    
                   6215:      /* end probability of death */
                   6216:                
                   6217:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6218:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6219:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6220:        for(i=1; i<=nlstate;i++){
                   6221:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6222:        }
                   6223:      } 
                   6224:      fprintf(ficresprobmorprev,"\n");
                   6225:                
                   6226:      fprintf(ficresvij,"%.0f ",age );
                   6227:      for(i=1; i<=nlstate;i++)
                   6228:        for(j=1; j<=nlstate;j++){
                   6229:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6230:        }
                   6231:      fprintf(ficresvij,"\n");
                   6232:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6233:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6234:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6235:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6236:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6237:    } /* End age */
                   6238:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6239:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6240:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6241:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6242:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6243:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6244:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6245:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6246:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6247:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6248:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6249:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6250:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6251:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6252:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6253:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6254:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6255:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6256:     */
1.218     brouard  6257:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6258:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6259: 
1.218     brouard  6260:    free_vector(xp,1,npar);
                   6261:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6262:    free_matrix(dnewm,1,nlstate,1,npar);
                   6263:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6264:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6265:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6266:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6267:    fclose(ficresprobmorprev);
                   6268:    fflush(ficgp);
                   6269:    fflush(fichtm); 
                   6270:  }  /* end varevsij */
1.126     brouard  6271: 
                   6272: /************ Variance of prevlim ******************/
1.269     brouard  6273:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6274: {
1.205     brouard  6275:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6276:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6277: 
1.268     brouard  6278:   double **dnewmpar,**doldm;
1.126     brouard  6279:   int i, j, nhstepm, hstepm;
                   6280:   double *xp;
                   6281:   double *gp, *gm;
                   6282:   double **gradg, **trgradg;
1.208     brouard  6283:   double **mgm, **mgp;
1.126     brouard  6284:   double age,agelim;
                   6285:   int theta;
                   6286:   
                   6287:   pstamp(ficresvpl);
1.288     brouard  6288:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6289:   fprintf(ficresvpl,"# Age ");
                   6290:   if(nresult >=1)
                   6291:     fprintf(ficresvpl," Result# ");
1.126     brouard  6292:   for(i=1; i<=nlstate;i++)
                   6293:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6294:   fprintf(ficresvpl,"\n");
                   6295: 
                   6296:   xp=vector(1,npar);
1.268     brouard  6297:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6298:   doldm=matrix(1,nlstate,1,nlstate);
                   6299:   
                   6300:   hstepm=1*YEARM; /* Every year of age */
                   6301:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6302:   agelim = AGESUP;
                   6303:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6304:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6305:     if (stepm >= YEARM) hstepm=1;
                   6306:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6307:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6308:     mgp=matrix(1,npar,1,nlstate);
                   6309:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6310:     gp=vector(1,nlstate);
                   6311:     gm=vector(1,nlstate);
                   6312: 
                   6313:     for(theta=1; theta <=npar; theta++){
                   6314:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6315:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6316:       }
1.288     brouard  6317:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6318:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6319:       /* else */
                   6320:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6321:       for(i=1;i<=nlstate;i++){
1.126     brouard  6322:        gp[i] = prlim[i][i];
1.208     brouard  6323:        mgp[theta][i] = prlim[i][i];
                   6324:       }
1.126     brouard  6325:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6326:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6327:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6328:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6329:       /* else */
                   6330:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6331:       for(i=1;i<=nlstate;i++){
1.126     brouard  6332:        gm[i] = prlim[i][i];
1.208     brouard  6333:        mgm[theta][i] = prlim[i][i];
                   6334:       }
1.126     brouard  6335:       for(i=1;i<=nlstate;i++)
                   6336:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6337:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6338:     } /* End theta */
                   6339: 
                   6340:     trgradg =matrix(1,nlstate,1,npar);
                   6341: 
                   6342:     for(j=1; j<=nlstate;j++)
                   6343:       for(theta=1; theta <=npar; theta++)
                   6344:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6345:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6346:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6347:     /*   for(j=1; j<=nlstate;j++){ */
                   6348:     /*         printf(" %d ",j); */
                   6349:     /*         for(theta=1; theta <=npar; theta++) */
                   6350:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6351:     /*         printf("\n "); */
                   6352:     /*   } */
                   6353:     /* } */
                   6354:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6355:     /*   printf("\n gradg %d ",(int)age); */
                   6356:     /*   for(j=1; j<=nlstate;j++){ */
                   6357:     /*         printf("%d ",j); */
                   6358:     /*         for(theta=1; theta <=npar; theta++) */
                   6359:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6360:     /*         printf("\n "); */
                   6361:     /*   } */
                   6362:     /* } */
1.126     brouard  6363: 
                   6364:     for(i=1;i<=nlstate;i++)
                   6365:       varpl[i][(int)age] =0.;
1.209     brouard  6366:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6367:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6368:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6369:     }else{
1.268     brouard  6370:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6371:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6372:     }
1.126     brouard  6373:     for(i=1;i<=nlstate;i++)
                   6374:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6375: 
                   6376:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6377:     if(nresult >=1)
                   6378:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6379:     for(i=1; i<=nlstate;i++){
1.126     brouard  6380:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6381:       /* for(j=1;j<=nlstate;j++) */
                   6382:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6383:     }
1.126     brouard  6384:     fprintf(ficresvpl,"\n");
                   6385:     free_vector(gp,1,nlstate);
                   6386:     free_vector(gm,1,nlstate);
1.208     brouard  6387:     free_matrix(mgm,1,npar,1,nlstate);
                   6388:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6389:     free_matrix(gradg,1,npar,1,nlstate);
                   6390:     free_matrix(trgradg,1,nlstate,1,npar);
                   6391:   } /* End age */
                   6392: 
                   6393:   free_vector(xp,1,npar);
                   6394:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6395:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6396: 
                   6397: }
                   6398: 
                   6399: 
                   6400: /************ Variance of backprevalence limit ******************/
1.269     brouard  6401:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6402: {
                   6403:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6404:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6405: 
                   6406:   double **dnewmpar,**doldm;
                   6407:   int i, j, nhstepm, hstepm;
                   6408:   double *xp;
                   6409:   double *gp, *gm;
                   6410:   double **gradg, **trgradg;
                   6411:   double **mgm, **mgp;
                   6412:   double age,agelim;
                   6413:   int theta;
                   6414:   
                   6415:   pstamp(ficresvbl);
                   6416:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6417:   fprintf(ficresvbl,"# Age ");
                   6418:   if(nresult >=1)
                   6419:     fprintf(ficresvbl," Result# ");
                   6420:   for(i=1; i<=nlstate;i++)
                   6421:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6422:   fprintf(ficresvbl,"\n");
                   6423: 
                   6424:   xp=vector(1,npar);
                   6425:   dnewmpar=matrix(1,nlstate,1,npar);
                   6426:   doldm=matrix(1,nlstate,1,nlstate);
                   6427:   
                   6428:   hstepm=1*YEARM; /* Every year of age */
                   6429:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6430:   agelim = AGEINF;
                   6431:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6432:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6433:     if (stepm >= YEARM) hstepm=1;
                   6434:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6435:     gradg=matrix(1,npar,1,nlstate);
                   6436:     mgp=matrix(1,npar,1,nlstate);
                   6437:     mgm=matrix(1,npar,1,nlstate);
                   6438:     gp=vector(1,nlstate);
                   6439:     gm=vector(1,nlstate);
                   6440: 
                   6441:     for(theta=1; theta <=npar; theta++){
                   6442:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6443:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6444:       }
                   6445:       if(mobilavproj > 0 )
                   6446:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6447:       else
                   6448:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6449:       for(i=1;i<=nlstate;i++){
                   6450:        gp[i] = bprlim[i][i];
                   6451:        mgp[theta][i] = bprlim[i][i];
                   6452:       }
                   6453:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6454:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6455:        if(mobilavproj > 0 )
                   6456:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6457:        else
                   6458:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6459:       for(i=1;i<=nlstate;i++){
                   6460:        gm[i] = bprlim[i][i];
                   6461:        mgm[theta][i] = bprlim[i][i];
                   6462:       }
                   6463:       for(i=1;i<=nlstate;i++)
                   6464:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6465:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6466:     } /* End theta */
                   6467: 
                   6468:     trgradg =matrix(1,nlstate,1,npar);
                   6469: 
                   6470:     for(j=1; j<=nlstate;j++)
                   6471:       for(theta=1; theta <=npar; theta++)
                   6472:        trgradg[j][theta]=gradg[theta][j];
                   6473:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6474:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6475:     /*   for(j=1; j<=nlstate;j++){ */
                   6476:     /*         printf(" %d ",j); */
                   6477:     /*         for(theta=1; theta <=npar; theta++) */
                   6478:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6479:     /*         printf("\n "); */
                   6480:     /*   } */
                   6481:     /* } */
                   6482:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6483:     /*   printf("\n gradg %d ",(int)age); */
                   6484:     /*   for(j=1; j<=nlstate;j++){ */
                   6485:     /*         printf("%d ",j); */
                   6486:     /*         for(theta=1; theta <=npar; theta++) */
                   6487:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6488:     /*         printf("\n "); */
                   6489:     /*   } */
                   6490:     /* } */
                   6491: 
                   6492:     for(i=1;i<=nlstate;i++)
                   6493:       varbpl[i][(int)age] =0.;
                   6494:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6495:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6496:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6497:     }else{
                   6498:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6499:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6500:     }
                   6501:     for(i=1;i<=nlstate;i++)
                   6502:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6503: 
                   6504:     fprintf(ficresvbl,"%.0f ",age );
                   6505:     if(nresult >=1)
                   6506:       fprintf(ficresvbl,"%d ",nres );
                   6507:     for(i=1; i<=nlstate;i++)
                   6508:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6509:     fprintf(ficresvbl,"\n");
                   6510:     free_vector(gp,1,nlstate);
                   6511:     free_vector(gm,1,nlstate);
                   6512:     free_matrix(mgm,1,npar,1,nlstate);
                   6513:     free_matrix(mgp,1,npar,1,nlstate);
                   6514:     free_matrix(gradg,1,npar,1,nlstate);
                   6515:     free_matrix(trgradg,1,nlstate,1,npar);
                   6516:   } /* End age */
                   6517: 
                   6518:   free_vector(xp,1,npar);
                   6519:   free_matrix(doldm,1,nlstate,1,npar);
                   6520:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6521: 
                   6522: }
                   6523: 
                   6524: /************ Variance of one-step probabilities  ******************/
                   6525: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6526:  {
                   6527:    int i, j=0,  k1, l1, tj;
                   6528:    int k2, l2, j1,  z1;
                   6529:    int k=0, l;
                   6530:    int first=1, first1, first2;
                   6531:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6532:    double **dnewm,**doldm;
                   6533:    double *xp;
                   6534:    double *gp, *gm;
                   6535:    double **gradg, **trgradg;
                   6536:    double **mu;
                   6537:    double age, cov[NCOVMAX+1];
                   6538:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6539:    int theta;
                   6540:    char fileresprob[FILENAMELENGTH];
                   6541:    char fileresprobcov[FILENAMELENGTH];
                   6542:    char fileresprobcor[FILENAMELENGTH];
                   6543:    double ***varpij;
                   6544: 
                   6545:    strcpy(fileresprob,"PROB_"); 
                   6546:    strcat(fileresprob,fileres);
                   6547:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6548:      printf("Problem with resultfile: %s\n", fileresprob);
                   6549:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6550:    }
                   6551:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6552:    strcat(fileresprobcov,fileresu);
                   6553:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6554:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6555:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6556:    }
                   6557:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6558:    strcat(fileresprobcor,fileresu);
                   6559:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6560:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6561:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6562:    }
                   6563:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6564:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6565:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6566:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6567:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6568:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6569:    pstamp(ficresprob);
                   6570:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6571:    fprintf(ficresprob,"# Age");
                   6572:    pstamp(ficresprobcov);
                   6573:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6574:    fprintf(ficresprobcov,"# Age");
                   6575:    pstamp(ficresprobcor);
                   6576:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6577:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6578: 
                   6579: 
1.222     brouard  6580:    for(i=1; i<=nlstate;i++)
                   6581:      for(j=1; j<=(nlstate+ndeath);j++){
                   6582:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6583:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6584:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6585:      }  
                   6586:    /* fprintf(ficresprob,"\n");
                   6587:       fprintf(ficresprobcov,"\n");
                   6588:       fprintf(ficresprobcor,"\n");
                   6589:    */
                   6590:    xp=vector(1,npar);
                   6591:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6592:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6593:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6594:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6595:    first=1;
                   6596:    fprintf(ficgp,"\n# Routine varprob");
                   6597:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6598:    fprintf(fichtm,"\n");
                   6599: 
1.288     brouard  6600:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6601:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6602:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6603: and drawn. It helps understanding how is the covariance between two incidences.\
                   6604:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6605:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6606: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6607: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6608: standard deviations wide on each axis. <br>\
                   6609:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6610:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6611: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6612: 
1.222     brouard  6613:    cov[1]=1;
                   6614:    /* tj=cptcoveff; */
1.225     brouard  6615:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6616:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6617:    j1=0;
1.224     brouard  6618:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6619:      if  (cptcovn>0) {
                   6620:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6621:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6622:        fprintf(ficresprob, "**********\n#\n");
                   6623:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6624:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6625:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6626:                        
1.222     brouard  6627:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6628:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6629:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6630:                        
                   6631:                        
1.222     brouard  6632:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6633:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6634:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6635:                        
1.222     brouard  6636:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6637:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6638:        fprintf(ficresprobcor, "**********\n#");    
                   6639:        if(invalidvarcomb[j1]){
                   6640:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6641:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6642:         continue;
                   6643:        }
                   6644:      }
                   6645:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6646:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6647:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6648:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6649:      for (age=bage; age<=fage; age ++){ 
                   6650:        cov[2]=age;
                   6651:        if(nagesqr==1)
                   6652:         cov[3]= age*age;
                   6653:        for (k=1; k<=cptcovn;k++) {
                   6654:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6655:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6656:                                                                    * 1  1 1 1 1
                   6657:                                                                    * 2  2 1 1 1
                   6658:                                                                    * 3  1 2 1 1
                   6659:                                                                    */
                   6660:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6661:        }
                   6662:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6663:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6664:        for (k=1; k<=cptcovprod;k++)
                   6665:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6666:                        
                   6667:                        
1.222     brouard  6668:        for(theta=1; theta <=npar; theta++){
                   6669:         for(i=1; i<=npar; i++)
                   6670:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6671:                                
1.222     brouard  6672:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6673:                                
1.222     brouard  6674:         k=0;
                   6675:         for(i=1; i<= (nlstate); i++){
                   6676:           for(j=1; j<=(nlstate+ndeath);j++){
                   6677:             k=k+1;
                   6678:             gp[k]=pmmij[i][j];
                   6679:           }
                   6680:         }
1.220     brouard  6681:                                
1.222     brouard  6682:         for(i=1; i<=npar; i++)
                   6683:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6684:                                
1.222     brouard  6685:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6686:         k=0;
                   6687:         for(i=1; i<=(nlstate); i++){
                   6688:           for(j=1; j<=(nlstate+ndeath);j++){
                   6689:             k=k+1;
                   6690:             gm[k]=pmmij[i][j];
                   6691:           }
                   6692:         }
1.220     brouard  6693:                                
1.222     brouard  6694:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6695:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6696:        }
1.126     brouard  6697: 
1.222     brouard  6698:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6699:         for(theta=1; theta <=npar; theta++)
                   6700:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6701:                        
1.222     brouard  6702:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6703:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6704:                        
1.222     brouard  6705:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6706:                        
1.222     brouard  6707:        k=0;
                   6708:        for(i=1; i<=(nlstate); i++){
                   6709:         for(j=1; j<=(nlstate+ndeath);j++){
                   6710:           k=k+1;
                   6711:           mu[k][(int) age]=pmmij[i][j];
                   6712:         }
                   6713:        }
                   6714:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6715:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6716:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6717:                        
1.222     brouard  6718:        /*printf("\n%d ",(int)age);
                   6719:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6720:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6721:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6722:         }*/
1.220     brouard  6723:                        
1.222     brouard  6724:        fprintf(ficresprob,"\n%d ",(int)age);
                   6725:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6726:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6727:                        
1.222     brouard  6728:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6729:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6730:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6731:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6732:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6733:        }
                   6734:        i=0;
                   6735:        for (k=1; k<=(nlstate);k++){
                   6736:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6737:           i++;
                   6738:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6739:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6740:           for (j=1; j<=i;j++){
                   6741:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6742:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6743:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6744:           }
                   6745:         }
                   6746:        }/* end of loop for state */
                   6747:      } /* end of loop for age */
                   6748:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6749:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6750:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6751:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6752:     
                   6753:      /* Confidence intervalle of pij  */
                   6754:      /*
                   6755:        fprintf(ficgp,"\nunset parametric;unset label");
                   6756:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6757:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6758:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6759:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6760:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6761:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6762:      */
                   6763:                
                   6764:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6765:      first1=1;first2=2;
                   6766:      for (k2=1; k2<=(nlstate);k2++){
                   6767:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6768:         if(l2==k2) continue;
                   6769:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6770:         for (k1=1; k1<=(nlstate);k1++){
                   6771:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6772:             if(l1==k1) continue;
                   6773:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6774:             if(i<=j) continue;
                   6775:             for (age=bage; age<=fage; age ++){ 
                   6776:               if ((int)age %5==0){
                   6777:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6778:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6779:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6780:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6781:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6782:                 c12=cv12/sqrt(v1*v2);
                   6783:                 /* Computing eigen value of matrix of covariance */
                   6784:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6785:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6786:                 if ((lc2 <0) || (lc1 <0) ){
                   6787:                   if(first2==1){
                   6788:                     first1=0;
                   6789:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6790:                   }
                   6791:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6792:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6793:                   /* lc2=fabs(lc2); */
                   6794:                 }
1.220     brouard  6795:                                                                
1.222     brouard  6796:                 /* Eigen vectors */
1.280     brouard  6797:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6798:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6799:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6800:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6801:                 }else
                   6802:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6803:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6804:                 v21=(lc1-v1)/cv12*v11;
                   6805:                 v12=-v21;
                   6806:                 v22=v11;
                   6807:                 tnalp=v21/v11;
                   6808:                 if(first1==1){
                   6809:                   first1=0;
                   6810:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6811:                 }
                   6812:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6813:                 /*printf(fignu*/
                   6814:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6815:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6816:                 if(first==1){
                   6817:                   first=0;
                   6818:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6819:                   fprintf(ficgp,"\nset parametric;unset label");
                   6820:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6821:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6822:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6823:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6824: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6825:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6826:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6827:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6828:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6829:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6830:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6831:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6832:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6833:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6834:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6835:                 }else{
                   6836:                   first=0;
                   6837:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6838:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6839:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6840:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6841:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6842:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6843:                 }/* if first */
                   6844:               } /* age mod 5 */
                   6845:             } /* end loop age */
                   6846:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6847:             first=1;
                   6848:           } /*l12 */
                   6849:         } /* k12 */
                   6850:        } /*l1 */
                   6851:      }/* k1 */
                   6852:    }  /* loop on combination of covariates j1 */
                   6853:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6854:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6855:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6856:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6857:    free_vector(xp,1,npar);
                   6858:    fclose(ficresprob);
                   6859:    fclose(ficresprobcov);
                   6860:    fclose(ficresprobcor);
                   6861:    fflush(ficgp);
                   6862:    fflush(fichtmcov);
                   6863:  }
1.126     brouard  6864: 
                   6865: 
                   6866: /******************* Printing html file ***********/
1.201     brouard  6867: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6868:                  int lastpass, int stepm, int weightopt, char model[],\
                   6869:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.296     brouard  6870:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int prevbcast, int estepm , \
                   6871:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateprojd, double dateback1, \
                   6872:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateprojf, double dateback2){
1.237     brouard  6873:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6874: 
                   6875:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6876:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6877: </ul>");
1.237     brouard  6878:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6879: </ul>", model);
1.214     brouard  6880:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6881:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6882:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6883:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6884:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6885:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6886:    fprintf(fichtm,"\
                   6887:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6888:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6889:    fprintf(fichtm,"\
1.217     brouard  6890:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6891:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6892:    fprintf(fichtm,"\
1.288     brouard  6893:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6894:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6895:    fprintf(fichtm,"\
1.288     brouard  6896:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  6897:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6898:    fprintf(fichtm,"\
1.211     brouard  6899:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6900:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6901:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6902:    if(prevfcast==1){
                   6903:      fprintf(fichtm,"\
                   6904:  - Prevalence projections by age and states:                           \
1.201     brouard  6905:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6906:    }
1.126     brouard  6907: 
                   6908: 
1.225     brouard  6909:    m=pow(2,cptcoveff);
1.222     brouard  6910:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6911: 
1.264     brouard  6912:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6913: 
                   6914:    jj1=0;
                   6915: 
                   6916:    fprintf(fichtm," \n<ul>");
                   6917:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6918:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6919:      if(m != 1 && TKresult[nres]!= k1)
                   6920:        continue;
                   6921:      jj1++;
                   6922:      if (cptcovn > 0) {
                   6923:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6924:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6925:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6926:        }
                   6927:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6928:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6929:        }
                   6930:        fprintf(fichtm,"\">");
                   6931:        
                   6932:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6933:        fprintf(fichtm,"************ Results for covariates");
                   6934:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6935:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6936:        }
                   6937:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6938:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6939:        }
                   6940:        if(invalidvarcomb[k1]){
                   6941:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6942:         continue;
                   6943:        }
                   6944:        fprintf(fichtm,"</a></li>");
                   6945:      } /* cptcovn >0 */
                   6946:    }
                   6947:      fprintf(fichtm," \n</ul>");
                   6948: 
1.222     brouard  6949:    jj1=0;
1.237     brouard  6950: 
                   6951:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6952:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6953:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6954:        continue;
1.220     brouard  6955: 
1.222     brouard  6956:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6957:      jj1++;
                   6958:      if (cptcovn > 0) {
1.264     brouard  6959:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6960:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6961:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6962:        }
                   6963:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6964:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6965:        }
                   6966:        fprintf(fichtm,"\"</a>");
                   6967:  
1.222     brouard  6968:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6969:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6970:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6971:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6972:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6973:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6974:        }
1.237     brouard  6975:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6976:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6977:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6978:       }
                   6979:        
1.230     brouard  6980:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6981:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6982:        if(invalidvarcomb[k1]){
                   6983:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6984:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   6985:         continue;
                   6986:        }
                   6987:      }
                   6988:      /* aij, bij */
1.259     brouard  6989:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  6990: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  6991:      /* Pij */
1.241     brouard  6992:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   6993: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  6994:      /* Quasi-incidences */
                   6995:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  6996:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  6997:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  6998: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   6999: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  7000:      /* Survival functions (period) in state j */
                   7001:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7002:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7003: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  7004:      }
                   7005:      /* State specific survival functions (period) */
                   7006:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7007:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
                   7008:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  7009:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  7010:      }
1.288     brouard  7011:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  7012:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7013:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7014: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  7015:      }
1.296     brouard  7016:      if(prevbcast==1){
1.288     brouard  7017:        /* Backward prevalence in each health state */
1.222     brouard  7018:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7019:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7020: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  7021:        }
1.217     brouard  7022:      }
1.222     brouard  7023:      if(prevfcast==1){
1.288     brouard  7024:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  7025:        for(cpt=1; cpt<=nlstate;cpt++){
1.288     brouard  7026:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.296     brouard  7027: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateprojd, dateprojf, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  7028:        }
                   7029:      }
1.296     brouard  7030:      if(prevbcast==1){
1.268     brouard  7031:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   7032:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  7033:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   7034:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   7035:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   7036: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7037:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  7038:        }
                   7039:      }
1.220     brouard  7040:         
1.222     brouard  7041:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  7042:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   7043: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  7044:      }
                   7045:      /* } /\* end i1 *\/ */
                   7046:    }/* End k1 */
                   7047:    fprintf(fichtm,"</ul>");
1.126     brouard  7048: 
1.222     brouard  7049:    fprintf(fichtm,"\
1.126     brouard  7050: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  7051:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  7052:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  7053: But because parameters are usually highly correlated (a higher incidence of disability \
                   7054: and a higher incidence of recovery can give very close observed transition) it might \
                   7055: be very useful to look not only at linear confidence intervals estimated from the \
                   7056: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   7057: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   7058: covariance matrix of the one-step probabilities. \
                   7059: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  7060: 
1.222     brouard  7061:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   7062:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   7063:    fprintf(fichtm,"\
1.126     brouard  7064:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7065:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  7066: 
1.222     brouard  7067:    fprintf(fichtm,"\
1.126     brouard  7068:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7069:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7070:    fprintf(fichtm,"\
1.126     brouard  7071:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7072:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7073:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7074:    fprintf(fichtm,"\
1.126     brouard  7075:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7076:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7077:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7078:    fprintf(fichtm,"\
1.288     brouard  7079:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7080:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7081:    fprintf(fichtm,"\
1.128     brouard  7082:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7083:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7084:    fprintf(fichtm,"\
1.288     brouard  7085:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7086:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7087: 
                   7088: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7089: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7090: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7091: /*     <br>",fileres,fileres,fileres,fileres); */
                   7092: /*  else  */
                   7093: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7094:    fflush(fichtm);
                   7095:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7096: 
1.225     brouard  7097:    m=pow(2,cptcoveff);
1.222     brouard  7098:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7099: 
1.222     brouard  7100:    jj1=0;
1.237     brouard  7101: 
1.241     brouard  7102:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7103:    for(k1=1; k1<=m;k1++){
1.253     brouard  7104:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7105:        continue;
1.222     brouard  7106:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7107:      jj1++;
1.126     brouard  7108:      if (cptcovn > 0) {
                   7109:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7110:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7111:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7112:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7113:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7114:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7115:       }
                   7116: 
1.126     brouard  7117:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7118: 
1.222     brouard  7119:        if(invalidvarcomb[k1]){
                   7120:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7121:         continue;
                   7122:        }
1.126     brouard  7123:      }
                   7124:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7125:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7126: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7127: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7128:      }
                   7129:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7130: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7131: true period expectancies (those weighted with period prevalences are also\
                   7132:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7133:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7134: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7135:      /* } /\* end i1 *\/ */
                   7136:    }/* End k1 */
1.241     brouard  7137:   }/* End nres */
1.222     brouard  7138:    fprintf(fichtm,"</ul>");
                   7139:    fflush(fichtm);
1.126     brouard  7140: }
                   7141: 
                   7142: /******************* Gnuplot file **************/
1.296     brouard  7143: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int prevbcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7144: 
                   7145:   char dirfileres[132],optfileres[132];
1.264     brouard  7146:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7147:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7148:   int lv=0, vlv=0, kl=0;
1.130     brouard  7149:   int ng=0;
1.201     brouard  7150:   int vpopbased;
1.223     brouard  7151:   int ioffset; /* variable offset for columns */
1.270     brouard  7152:   int iyearc=1; /* variable column for year of projection  */
                   7153:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7154:   int nres=0; /* Index of resultline */
1.266     brouard  7155:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7156: 
1.126     brouard  7157: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7158: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7159: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7160: /*   } */
                   7161: 
                   7162:   /*#ifdef windows */
                   7163:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7164:   /*#endif */
1.225     brouard  7165:   m=pow(2,cptcoveff);
1.126     brouard  7166: 
1.274     brouard  7167:   /* diagram of the model */
                   7168:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7169:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7170:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7171:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7172: 
                   7173:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7174:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7175:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7176:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7177:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7178:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7179:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7180: 
1.202     brouard  7181:   /* Contribution to likelihood */
                   7182:   /* Plot the probability implied in the likelihood */
1.223     brouard  7183:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7184:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7185:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7186:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7187: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7188:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7189: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7190:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7191:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7192:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7193:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7194:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7195:   for (i=1; i<= nlstate ; i ++) {
                   7196:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7197:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7198:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7199:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7200:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7201:     }
                   7202:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7203:   }
                   7204:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7205:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7206:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7207:   fprintf(ficgp,"\nset out;unset log\n");
                   7208:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7209: 
1.126     brouard  7210:   strcpy(dirfileres,optionfilefiname);
                   7211:   strcpy(optfileres,"vpl");
1.223     brouard  7212:   /* 1eme*/
1.238     brouard  7213:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7214:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7215:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7216:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7217:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7218:          continue;
                   7219:        /* We are interested in selected combination by the resultline */
1.246     brouard  7220:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7221:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7222:        strcpy(gplotlabel,"(");
1.238     brouard  7223:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7224:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7225:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7226:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7227:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7228:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7229:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7230:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7231:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7232:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7233:        }
                   7234:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7235:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7236:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7237:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7238:        }
                   7239:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7240:        /* printf("\n#\n"); */
1.238     brouard  7241:        fprintf(ficgp,"\n#\n");
                   7242:        if(invalidvarcomb[k1]){
1.260     brouard  7243:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7244:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7245:          continue;
                   7246:        }
1.235     brouard  7247:       
1.241     brouard  7248:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7249:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7250:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7251:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7252:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7253:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7254:       /* k1-1 error should be nres-1*/
1.238     brouard  7255:        for (i=1; i<= nlstate ; i ++) {
                   7256:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7257:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7258:        }
1.288     brouard  7259:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7260:        for (i=1; i<= nlstate ; i ++) {
                   7261:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7262:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7263:        } 
1.260     brouard  7264:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7265:        for (i=1; i<= nlstate ; i ++) {
                   7266:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7267:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7268:        }  
1.265     brouard  7269:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7270:        
                   7271:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7272:         if(cptcoveff ==0){
1.271     brouard  7273:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7274:        }else{
                   7275:          kl=0;
                   7276:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7277:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7278:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7279:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7280:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7281:            vlv= nbcode[Tvaraff[k]][lv];
                   7282:            kl++;
                   7283:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7284:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7285:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7286:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7287:            if(k==cptcoveff){
                   7288:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7289:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7290:            }else{
                   7291:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7292:              kl++;
                   7293:            }
                   7294:          } /* end covariate */
                   7295:        } /* end if no covariate */
                   7296: 
1.296     brouard  7297:        if(prevbcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
1.238     brouard  7298:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7299:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7300:          if(cptcoveff ==0){
1.245     brouard  7301:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7302:          }else{
                   7303:            kl=0;
                   7304:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7305:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7306:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7307:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7308:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7309:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7310:              kl++;
1.238     brouard  7311:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7312:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7313:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7314:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7315:              if(k==cptcoveff){
1.245     brouard  7316:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7317:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7318:              }else{
                   7319:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7320:                kl++;
                   7321:              }
                   7322:            } /* end covariate */
                   7323:          } /* end if no covariate */
1.296     brouard  7324:          if(prevbcast == 1){
1.268     brouard  7325:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7326:            /* k1-1 error should be nres-1*/
                   7327:            for (i=1; i<= nlstate ; i ++) {
                   7328:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7329:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7330:            }
1.271     brouard  7331:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7332:            for (i=1; i<= nlstate ; i ++) {
                   7333:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7334:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7335:            } 
1.276     brouard  7336:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7337:            for (i=1; i<= nlstate ; i ++) {
                   7338:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7339:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7340:            } 
1.274     brouard  7341:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7342:          } /* end if backprojcast */
1.296     brouard  7343:        } /* end if prevbcast */
1.276     brouard  7344:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7345:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7346:       } /* nres */
1.201     brouard  7347:     } /* k1 */
                   7348:   } /* cpt */
1.235     brouard  7349: 
                   7350:   
1.126     brouard  7351:   /*2 eme*/
1.238     brouard  7352:   for (k1=1; k1<= m ; k1 ++){  
                   7353:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7354:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7355:        continue;
                   7356:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7357:       strcpy(gplotlabel,"(");
1.238     brouard  7358:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7359:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7360:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7361:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7362:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7363:        vlv= nbcode[Tvaraff[k]][lv];
                   7364:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7365:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7366:       }
1.237     brouard  7367:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7368:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7369:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7370:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7371:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7372:       }
1.264     brouard  7373:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7374:       fprintf(ficgp,"\n#\n");
1.223     brouard  7375:       if(invalidvarcomb[k1]){
                   7376:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7377:        continue;
                   7378:       }
1.219     brouard  7379:                        
1.241     brouard  7380:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7381:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7382:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7383:        if(vpopbased==0){
1.238     brouard  7384:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7385:        }else
1.238     brouard  7386:          fprintf(ficgp,"\nreplot ");
                   7387:        for (i=1; i<= nlstate+1 ; i ++) {
                   7388:          k=2*i;
1.261     brouard  7389:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7390:          for (j=1; j<= nlstate+1 ; j ++) {
                   7391:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7392:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7393:          }   
                   7394:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7395:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7396:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7397:          for (j=1; j<= nlstate+1 ; j ++) {
                   7398:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7399:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7400:          }   
                   7401:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7402:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7403:          for (j=1; j<= nlstate+1 ; j ++) {
                   7404:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7405:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7406:          }   
                   7407:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7408:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7409:        } /* state */
                   7410:       } /* vpopbased */
1.264     brouard  7411:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7412:     } /* end nres */
                   7413:   } /* k1 end 2 eme*/
                   7414:        
                   7415:        
                   7416:   /*3eme*/
                   7417:   for (k1=1; k1<= m ; k1 ++){
                   7418:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7419:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7420:        continue;
                   7421: 
                   7422:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7423:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7424:        strcpy(gplotlabel,"(");
1.238     brouard  7425:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7426:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7427:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7428:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7429:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7430:          vlv= nbcode[Tvaraff[k]][lv];
                   7431:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7432:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7433:        }
                   7434:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7435:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7436:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7437:        }       
1.264     brouard  7438:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7439:        fprintf(ficgp,"\n#\n");
                   7440:        if(invalidvarcomb[k1]){
                   7441:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7442:          continue;
                   7443:        }
                   7444:                        
                   7445:        /*       k=2+nlstate*(2*cpt-2); */
                   7446:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7447:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7448:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7449:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7450: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7451:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7452:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7453:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7454:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7455:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7456:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7457:                                
1.238     brouard  7458:        */
                   7459:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7460:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7461:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7462:                                
1.238     brouard  7463:        } 
1.261     brouard  7464:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7465:       }
1.264     brouard  7466:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7467:     } /* end nres */
                   7468:   } /* end kl 3eme */
1.126     brouard  7469:   
1.223     brouard  7470:   /* 4eme */
1.201     brouard  7471:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7472:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7473:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7474:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7475:        continue;
1.238     brouard  7476:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7477:        strcpy(gplotlabel,"(");
1.238     brouard  7478:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7479:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7480:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7481:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7482:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7483:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7484:          vlv= nbcode[Tvaraff[k]][lv];
                   7485:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7486:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7487:        }
                   7488:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7489:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7490:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7491:        }       
1.264     brouard  7492:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7493:        fprintf(ficgp,"\n#\n");
                   7494:        if(invalidvarcomb[k1]){
                   7495:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7496:          continue;
1.223     brouard  7497:        }
1.238     brouard  7498:       
1.241     brouard  7499:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7500:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7501:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7502: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7503:        k=3;
                   7504:        for (i=1; i<= nlstate ; i ++){
                   7505:          if(i==1){
                   7506:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7507:          }else{
                   7508:            fprintf(ficgp,", '' ");
                   7509:          }
                   7510:          l=(nlstate+ndeath)*(i-1)+1;
                   7511:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7512:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7513:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7514:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7515:        } /* nlstate */
1.264     brouard  7516:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7517:       } /* end cpt state*/ 
                   7518:     } /* end nres */
                   7519:   } /* end covariate k1 */  
                   7520: 
1.220     brouard  7521: /* 5eme */
1.201     brouard  7522:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7523:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7524:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7525:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7526:        continue;
1.238     brouard  7527:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7528:        strcpy(gplotlabel,"(");
1.238     brouard  7529:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7530:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7531:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7532:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7533:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7534:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7535:          vlv= nbcode[Tvaraff[k]][lv];
                   7536:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7537:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7538:        }
                   7539:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7540:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7541:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7542:        }       
1.264     brouard  7543:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7544:        fprintf(ficgp,"\n#\n");
                   7545:        if(invalidvarcomb[k1]){
                   7546:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7547:          continue;
                   7548:        }
1.227     brouard  7549:       
1.241     brouard  7550:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7551:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7552:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7553: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7554:        k=3;
                   7555:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7556:          if(j==1)
                   7557:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7558:          else
                   7559:            fprintf(ficgp,", '' ");
                   7560:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7561:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7562:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7563:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7564:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7565:        } /* nlstate */
                   7566:        fprintf(ficgp,", '' ");
                   7567:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7568:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7569:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7570:          if(j < nlstate)
                   7571:            fprintf(ficgp,"$%d +",k+l);
                   7572:          else
                   7573:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7574:        }
1.264     brouard  7575:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7576:       } /* end cpt state*/ 
                   7577:     } /* end covariate */  
                   7578:   } /* end nres */
1.227     brouard  7579:   
1.220     brouard  7580: /* 6eme */
1.202     brouard  7581:   /* CV preval stable (period) for each covariate */
1.237     brouard  7582:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7583:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7584:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7585:       continue;
1.255     brouard  7586:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7587:       strcpy(gplotlabel,"(");      
1.288     brouard  7588:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7589:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7590:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7591:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7592:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7593:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7594:        vlv= nbcode[Tvaraff[k]][lv];
                   7595:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7596:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7597:       }
1.237     brouard  7598:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7599:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7600:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7601:       }        
1.264     brouard  7602:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7603:       fprintf(ficgp,"\n#\n");
1.223     brouard  7604:       if(invalidvarcomb[k1]){
1.227     brouard  7605:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7606:        continue;
1.223     brouard  7607:       }
1.227     brouard  7608:       
1.241     brouard  7609:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7610:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7611:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7612: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7613:       k=3; /* Offset */
1.255     brouard  7614:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7615:        if(i==1)
                   7616:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7617:        else
                   7618:          fprintf(ficgp,", '' ");
1.255     brouard  7619:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7620:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7621:        for (j=2; j<= nlstate ; j ++)
                   7622:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7623:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7624:       } /* nlstate */
1.264     brouard  7625:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7626:     } /* end cpt state*/ 
                   7627:   } /* end covariate */  
1.227     brouard  7628:   
                   7629:   
1.220     brouard  7630: /* 7eme */
1.296     brouard  7631:   if(prevbcast == 1){
1.288     brouard  7632:     /* CV backward prevalence  for each covariate */
1.237     brouard  7633:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7634:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7635:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7636:        continue;
1.268     brouard  7637:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7638:        strcpy(gplotlabel,"(");      
1.288     brouard  7639:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7640:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7641:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7642:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7643:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7644:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7645:          vlv= nbcode[Tvaraff[k]][lv];
                   7646:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7647:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7648:        }
1.237     brouard  7649:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7650:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7651:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7652:        }       
1.264     brouard  7653:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7654:        fprintf(ficgp,"\n#\n");
                   7655:        if(invalidvarcomb[k1]){
                   7656:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7657:          continue;
                   7658:        }
                   7659:        
1.241     brouard  7660:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7661:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7662:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7663: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7664:        k=3; /* Offset */
1.268     brouard  7665:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7666:          if(i==1)
                   7667:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7668:          else
                   7669:            fprintf(ficgp,", '' ");
                   7670:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7671:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7672:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7673:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7674:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7675:          /* for (j=2; j<= nlstate ; j ++) */
                   7676:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7677:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7678:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7679:        } /* nlstate */
1.264     brouard  7680:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7681:       } /* end cpt state*/ 
                   7682:     } /* end covariate */  
1.296     brouard  7683:   } /* End if prevbcast */
1.218     brouard  7684:   
1.223     brouard  7685:   /* 8eme */
1.218     brouard  7686:   if(prevfcast==1){
1.288     brouard  7687:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7688:     
1.237     brouard  7689:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7690:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7691:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7692:        continue;
1.211     brouard  7693:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7694:        strcpy(gplotlabel,"(");      
1.288     brouard  7695:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7696:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7697:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7698:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7699:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7700:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7701:          vlv= nbcode[Tvaraff[k]][lv];
                   7702:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7703:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7704:        }
1.237     brouard  7705:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7706:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7707:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7708:        }       
1.264     brouard  7709:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7710:        fprintf(ficgp,"\n#\n");
                   7711:        if(invalidvarcomb[k1]){
                   7712:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7713:          continue;
                   7714:        }
                   7715:        
                   7716:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7717:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7718:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7719:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7720: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7721: 
                   7722:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7723:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7724:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7725:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7726:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7727:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7728:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7729:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7730:          if(i==istart){
1.227     brouard  7731:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7732:          }else{
                   7733:            fprintf(ficgp,",\\\n '' ");
                   7734:          }
                   7735:          if(cptcoveff ==0){ /* No covariate */
                   7736:            ioffset=2; /* Age is in 2 */
                   7737:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7738:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7739:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7740:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7741:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7742:            if(i==nlstate+1){
1.270     brouard  7743:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7744:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7745:              fprintf(ficgp,",\\\n '' ");
                   7746:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7747:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7748:                     offyear,                           \
1.268     brouard  7749:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7750:            }else
1.227     brouard  7751:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7752:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7753:          }else{ /* more than 2 covariates */
1.270     brouard  7754:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7755:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7756:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7757:            iyearc=ioffset-1;
                   7758:            iagec=ioffset;
1.227     brouard  7759:            fprintf(ficgp," u %d:(",ioffset); 
                   7760:            kl=0;
                   7761:            strcpy(gplotcondition,"(");
                   7762:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7763:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7764:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7765:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7766:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7767:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7768:              kl++;
                   7769:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7770:              kl++;
                   7771:              if(k <cptcoveff && cptcoveff>1)
                   7772:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7773:            }
                   7774:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7775:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7776:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7777:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7778:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7779:            if(i==nlstate+1){
1.270     brouard  7780:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7781:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7782:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7783:              fprintf(ficgp," u %d:(",iagec); 
                   7784:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7785:                      iyearc, iagec, offyear,                           \
                   7786:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7787: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7788:            }else{
                   7789:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7790:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7791:            }
                   7792:          } /* end if covariate */
                   7793:        } /* nlstate */
1.264     brouard  7794:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7795:       } /* end cpt state*/
                   7796:     } /* end covariate */
                   7797:   } /* End if prevfcast */
1.227     brouard  7798:   
1.296     brouard  7799:   if(prevbcast==1){
1.268     brouard  7800:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7801:     
                   7802:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7803:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7804:       if(m != 1 && TKresult[nres]!= k1)
                   7805:        continue;
                   7806:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7807:        strcpy(gplotlabel,"(");      
                   7808:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7809:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7810:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7811:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7812:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7813:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7814:          vlv= nbcode[Tvaraff[k]][lv];
                   7815:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7816:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7817:        }
                   7818:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7819:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7820:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7821:        }       
                   7822:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7823:        fprintf(ficgp,"\n#\n");
                   7824:        if(invalidvarcomb[k1]){
                   7825:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7826:          continue;
                   7827:        }
                   7828:        
                   7829:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7830:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7831:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7832:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7833: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7834: 
                   7835:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7836:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7837:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7838:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7839:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7840:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7841:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7842:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7843:          if(i==istart){
                   7844:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7845:          }else{
                   7846:            fprintf(ficgp,",\\\n '' ");
                   7847:          }
                   7848:          if(cptcoveff ==0){ /* No covariate */
                   7849:            ioffset=2; /* Age is in 2 */
                   7850:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7851:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7852:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7853:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7854:            fprintf(ficgp," u %d:(", ioffset); 
                   7855:            if(i==nlstate+1){
1.270     brouard  7856:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7857:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7858:              fprintf(ficgp,",\\\n '' ");
                   7859:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7860:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7861:                     offbyear,                          \
                   7862:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7863:            }else
                   7864:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7865:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7866:          }else{ /* more than 2 covariates */
1.270     brouard  7867:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7868:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7869:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7870:            iyearc=ioffset-1;
                   7871:            iagec=ioffset;
1.268     brouard  7872:            fprintf(ficgp," u %d:(",ioffset); 
                   7873:            kl=0;
                   7874:            strcpy(gplotcondition,"(");
                   7875:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7876:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7877:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7878:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7879:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7880:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7881:              kl++;
                   7882:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7883:              kl++;
                   7884:              if(k <cptcoveff && cptcoveff>1)
                   7885:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7886:            }
                   7887:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7888:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7889:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7890:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7891:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7892:            if(i==nlstate+1){
1.270     brouard  7893:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7894:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7895:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7896:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7897:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7898:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7899:                      iyearc,iagec,offbyear,                            \
                   7900:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7901: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7902:            }else{
                   7903:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7904:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7905:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7906:            }
                   7907:          } /* end if covariate */
                   7908:        } /* nlstate */
                   7909:        fprintf(ficgp,"\nset out; unset label;\n");
                   7910:       } /* end cpt state*/
                   7911:     } /* end covariate */
1.296     brouard  7912:   } /* End if prevbcast */
1.268     brouard  7913:   
1.227     brouard  7914:   
1.238     brouard  7915:   /* 9eme writing MLE parameters */
                   7916:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7917:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7918:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7919:     for(k=1; k <=(nlstate+ndeath); k++){
                   7920:       if (k != i) {
1.227     brouard  7921:        fprintf(ficgp,"#   current state %d\n",k);
                   7922:        for(j=1; j <=ncovmodel; j++){
                   7923:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7924:          jk++; 
                   7925:        }
                   7926:        fprintf(ficgp,"\n");
1.126     brouard  7927:       }
                   7928:     }
1.223     brouard  7929:   }
1.187     brouard  7930:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7931:   
1.145     brouard  7932:   /*goto avoid;*/
1.238     brouard  7933:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7934:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7935:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7936:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7937:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7938:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7939:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7940:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7941:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7942:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7943:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7944:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7945:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7946:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7947:   fprintf(ficgp,"#\n");
1.223     brouard  7948:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7949:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7950:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7951:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7952:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7953:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7954:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7955:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7956:        continue;
1.264     brouard  7957:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7958:       strcpy(gplotlabel,"(");
1.276     brouard  7959:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  7960:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7961:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7962:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7963:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7964:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7965:        vlv= nbcode[Tvaraff[k]][lv];
                   7966:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7967:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7968:       }
1.237     brouard  7969:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7970:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7971:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7972:       }        
1.264     brouard  7973:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7974:       fprintf(ficgp,"\n#\n");
1.264     brouard  7975:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  7976:       fprintf(ficgp,"\nset key outside ");
                   7977:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   7978:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7979:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7980:       if (ng==1){
                   7981:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7982:        fprintf(ficgp,"\nunset log y");
                   7983:       }else if (ng==2){
                   7984:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   7985:        fprintf(ficgp,"\nset log y");
                   7986:       }else if (ng==3){
                   7987:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   7988:        fprintf(ficgp,"\nset log y");
                   7989:       }else
                   7990:        fprintf(ficgp,"\nunset title ");
                   7991:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   7992:       i=1;
                   7993:       for(k2=1; k2<=nlstate; k2++) {
                   7994:        k3=i;
                   7995:        for(k=1; k<=(nlstate+ndeath); k++) {
                   7996:          if (k != k2){
                   7997:            switch( ng) {
                   7998:            case 1:
                   7999:              if(nagesqr==0)
                   8000:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   8001:              else /* nagesqr =1 */
                   8002:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8003:              break;
                   8004:            case 2: /* ng=2 */
                   8005:              if(nagesqr==0)
                   8006:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   8007:              else /* nagesqr =1 */
                   8008:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8009:              break;
                   8010:            case 3:
                   8011:              if(nagesqr==0)
                   8012:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   8013:              else /* nagesqr =1 */
                   8014:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   8015:              break;
                   8016:            }
                   8017:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  8018:            ijp=1; /* product no age */
                   8019:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   8020:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  8021:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  8022:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8023:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   8024:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8025:                    if(DummyV[j]==0){
                   8026:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   8027:                    }else{ /* quantitative */
                   8028:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   8029:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8030:                    }
                   8031:                    ij++;
1.237     brouard  8032:                  }
1.268     brouard  8033:                } 
                   8034:              }else if(cptcovprod >0){
                   8035:                if(j==Tprod[ijp]) { /* */ 
                   8036:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   8037:                  if(ijp <=cptcovprod) { /* Product */
                   8038:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   8039:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   8040:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   8041:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   8042:                      }else{ /* Vn is dummy and Vm is quanti */
                   8043:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   8044:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8045:                      }
                   8046:                    }else{ /* Vn*Vm Vn is quanti */
                   8047:                      if(DummyV[Tvard[ijp][2]]==0){
                   8048:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   8049:                      }else{ /* Both quanti */
                   8050:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8051:                      }
1.237     brouard  8052:                    }
1.268     brouard  8053:                    ijp++;
1.237     brouard  8054:                  }
1.268     brouard  8055:                } /* end Tprod */
1.237     brouard  8056:              } else{  /* simple covariate */
1.264     brouard  8057:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  8058:                if(Dummy[j]==0){
                   8059:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   8060:                }else{ /* quantitative */
                   8061:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  8062:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  8063:                }
1.237     brouard  8064:              } /* end simple */
                   8065:            } /* end j */
1.223     brouard  8066:          }else{
                   8067:            i=i-ncovmodel;
                   8068:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8069:              fprintf(ficgp," (1.");
                   8070:          }
1.227     brouard  8071:          
1.223     brouard  8072:          if(ng != 1){
                   8073:            fprintf(ficgp,")/(1");
1.227     brouard  8074:            
1.264     brouard  8075:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8076:              if(nagesqr==0)
1.264     brouard  8077:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8078:              else /* nagesqr =1 */
1.264     brouard  8079:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8080:               
1.223     brouard  8081:              ij=1;
                   8082:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8083:                 if(cptcovage >0){ 
                   8084:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8085:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8086:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8087:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8088:                       ij++;
                   8089:                     }
                   8090:                   }
                   8091:                 }else
                   8092:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8093:              }
                   8094:              fprintf(ficgp,")");
                   8095:            }
                   8096:            fprintf(ficgp,")");
                   8097:            if(ng ==2)
1.276     brouard  8098:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8099:            else /* ng= 3 */
1.276     brouard  8100:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8101:          }else{ /* end ng <> 1 */
                   8102:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8103:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8104:          }
                   8105:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8106:            fprintf(ficgp,",");
                   8107:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8108:            fprintf(ficgp,",");
                   8109:          i=i+ncovmodel;
                   8110:        } /* end k */
                   8111:       } /* end k2 */
1.276     brouard  8112:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8113:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8114:     } /* end k1 */
1.223     brouard  8115:   } /* end ng */
                   8116:   /* avoid: */
                   8117:   fflush(ficgp); 
1.126     brouard  8118: }  /* end gnuplot */
                   8119: 
                   8120: 
                   8121: /*************** Moving average **************/
1.219     brouard  8122: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8123:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8124:    
1.222     brouard  8125:    int i, cpt, cptcod;
                   8126:    int modcovmax =1;
                   8127:    int mobilavrange, mob;
                   8128:    int iage=0;
1.288     brouard  8129:    int firstA1=0, firstA2=0;
1.222     brouard  8130: 
1.266     brouard  8131:    double sum=0., sumr=0.;
1.222     brouard  8132:    double age;
1.266     brouard  8133:    double *sumnewp, *sumnewm, *sumnewmr;
                   8134:    double *agemingood, *agemaxgood; 
                   8135:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8136:   
                   8137:   
1.278     brouard  8138:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8139:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8140: 
                   8141:    sumnewp = vector(1,ncovcombmax);
                   8142:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8143:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8144:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8145:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8146:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8147:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8148: 
                   8149:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8150:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8151:      sumnewp[cptcod]=0.;
1.266     brouard  8152:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8153:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8154:    }
                   8155:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8156:   
1.266     brouard  8157:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8158:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8159:      else mobilavrange=mobilav;
                   8160:      for (age=bage; age<=fage; age++)
                   8161:        for (i=1; i<=nlstate;i++)
                   8162:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8163:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8164:      /* We keep the original values on the extreme ages bage, fage and for 
                   8165:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8166:        we use a 5 terms etc. until the borders are no more concerned. 
                   8167:      */ 
                   8168:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8169:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8170:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8171:           sumnewm[cptcod]=0.;
                   8172:           for (i=1; i<=nlstate;i++){
1.222     brouard  8173:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8174:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8175:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8176:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8177:             }
                   8178:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8179:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8180:           } /* end i */
                   8181:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8182:         } /* end cptcod */
1.222     brouard  8183:        }/* end age */
                   8184:      }/* end mob */
1.266     brouard  8185:    }else{
                   8186:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8187:      return -1;
1.266     brouard  8188:    }
                   8189: 
                   8190:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8191:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8192:      if(invalidvarcomb[cptcod]){
                   8193:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8194:        continue;
                   8195:      }
1.219     brouard  8196: 
1.266     brouard  8197:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8198:        sumnewm[cptcod]=0.;
                   8199:        sumnewmr[cptcod]=0.;
                   8200:        for (i=1; i<=nlstate;i++){
                   8201:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8202:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8203:        }
                   8204:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8205:         agemingoodr[cptcod]=age;
                   8206:        }
                   8207:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8208:           agemingood[cptcod]=age;
                   8209:        }
                   8210:      } /* age */
                   8211:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8212:        sumnewm[cptcod]=0.;
1.266     brouard  8213:        sumnewmr[cptcod]=0.;
1.222     brouard  8214:        for (i=1; i<=nlstate;i++){
                   8215:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8216:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8217:        }
                   8218:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8219:         agemaxgoodr[cptcod]=age;
1.222     brouard  8220:        }
                   8221:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8222:         agemaxgood[cptcod]=age;
                   8223:        }
                   8224:      } /* age */
                   8225:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8226:      /* but they will change */
1.288     brouard  8227:      firstA1=0;firstA2=0;
1.266     brouard  8228:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8229:        sumnewm[cptcod]=0.;
                   8230:        sumnewmr[cptcod]=0.;
                   8231:        for (i=1; i<=nlstate;i++){
                   8232:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8233:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8234:        }
                   8235:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8236:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8237:           agemaxgoodr[cptcod]=age;  /* age min */
                   8238:           for (i=1; i<=nlstate;i++)
                   8239:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8240:         }else{ /* bad we change the value with the values of good ages */
                   8241:           for (i=1; i<=nlstate;i++){
                   8242:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8243:           } /* i */
                   8244:         } /* end bad */
                   8245:        }else{
                   8246:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8247:           agemaxgood[cptcod]=age;
                   8248:         }else{ /* bad we change the value with the values of good ages */
                   8249:           for (i=1; i<=nlstate;i++){
                   8250:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8251:           } /* i */
                   8252:         } /* end bad */
                   8253:        }/* end else */
                   8254:        sum=0.;sumr=0.;
                   8255:        for (i=1; i<=nlstate;i++){
                   8256:         sum+=mobaverage[(int)age][i][cptcod];
                   8257:         sumr+=probs[(int)age][i][cptcod];
                   8258:        }
                   8259:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8260:         if(!firstA1){
                   8261:           firstA1=1;
                   8262:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8263:         }
                   8264:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8265:        } /* end bad */
                   8266:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8267:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8268:         if(!firstA2){
                   8269:           firstA2=1;
                   8270:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8271:         }
                   8272:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8273:        } /* end bad */
                   8274:      }/* age */
1.266     brouard  8275: 
                   8276:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8277:        sumnewm[cptcod]=0.;
1.266     brouard  8278:        sumnewmr[cptcod]=0.;
1.222     brouard  8279:        for (i=1; i<=nlstate;i++){
                   8280:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8281:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8282:        } 
                   8283:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8284:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8285:           agemingoodr[cptcod]=age;
                   8286:           for (i=1; i<=nlstate;i++)
                   8287:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8288:         }else{ /* bad we change the value with the values of good ages */
                   8289:           for (i=1; i<=nlstate;i++){
                   8290:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8291:           } /* i */
                   8292:         } /* end bad */
                   8293:        }else{
                   8294:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8295:           agemingood[cptcod]=age;
                   8296:         }else{ /* bad */
                   8297:           for (i=1; i<=nlstate;i++){
                   8298:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8299:           } /* i */
                   8300:         } /* end bad */
                   8301:        }/* end else */
                   8302:        sum=0.;sumr=0.;
                   8303:        for (i=1; i<=nlstate;i++){
                   8304:         sum+=mobaverage[(int)age][i][cptcod];
                   8305:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8306:        }
1.266     brouard  8307:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8308:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8309:        } /* end bad */
                   8310:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8311:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8312:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8313:        } /* end bad */
                   8314:      }/* age */
1.266     brouard  8315: 
1.222     brouard  8316:                
                   8317:      for (age=bage; age<=fage; age++){
1.235     brouard  8318:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8319:        sumnewp[cptcod]=0.;
                   8320:        sumnewm[cptcod]=0.;
                   8321:        for (i=1; i<=nlstate;i++){
                   8322:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8323:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8324:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8325:        }
                   8326:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8327:      }
                   8328:      /* printf("\n"); */
                   8329:      /* } */
1.266     brouard  8330: 
1.222     brouard  8331:      /* brutal averaging */
1.266     brouard  8332:      /* for (i=1; i<=nlstate;i++){ */
                   8333:      /*   for (age=1; age<=bage; age++){ */
                   8334:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8335:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8336:      /*   }     */
                   8337:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8338:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8339:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8340:      /*   } */
                   8341:      /* } /\* end i status *\/ */
                   8342:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8343:      /*   for (age=1; age<=AGESUP; age++){ */
                   8344:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8345:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8346:      /*   } */
                   8347:      /* } */
1.222     brouard  8348:    }/* end cptcod */
1.266     brouard  8349:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8350:    free_vector(agemaxgood,1, ncovcombmax);
                   8351:    free_vector(agemingood,1, ncovcombmax);
                   8352:    free_vector(agemingoodr,1, ncovcombmax);
                   8353:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8354:    free_vector(sumnewm,1, ncovcombmax);
                   8355:    free_vector(sumnewp,1, ncovcombmax);
                   8356:    return 0;
                   8357:  }/* End movingaverage */
1.218     brouard  8358:  
1.126     brouard  8359: 
1.296     brouard  8360:  
1.126     brouard  8361: /************** Forecasting ******************/
1.296     brouard  8362: /* void prevforecast(char fileres[], double dateintmean, double anprojd, double mprojd, double jprojd, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anprojf, double p[], int cptcoveff)*/
                   8363: void prevforecast(char fileres[], double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8364:   /* dateintemean, mean date of interviews
                   8365:      dateprojd, year, month, day of starting projection 
                   8366:      dateprojf date of end of projection;year of end of projection (same day and month as proj1).
1.126     brouard  8367:      agemin, agemax range of age
                   8368:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8369:   */
1.296     brouard  8370:   /* double anprojd, mprojd, jprojd; */
                   8371:   /* double anprojf, mprojf, jprojf; */
1.267     brouard  8372:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8373:   double agec; /* generic age */
1.296     brouard  8374:   double agelim, ppij, yp,yp1,yp2;
1.126     brouard  8375:   double *popeffectif,*popcount;
                   8376:   double ***p3mat;
1.218     brouard  8377:   /* double ***mobaverage; */
1.126     brouard  8378:   char fileresf[FILENAMELENGTH];
                   8379: 
                   8380:   agelim=AGESUP;
1.211     brouard  8381:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8382:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8383:      We still use firstpass and lastpass as another selection.
                   8384:   */
1.214     brouard  8385:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8386:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8387:  
1.201     brouard  8388:   strcpy(fileresf,"F_"); 
                   8389:   strcat(fileresf,fileresu);
1.126     brouard  8390:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8391:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8392:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8393:   }
1.235     brouard  8394:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8395:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8396: 
1.225     brouard  8397:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8398: 
                   8399: 
                   8400:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8401:   if (stepm<=12) stepsize=1;
                   8402:   if(estepm < stepm){
                   8403:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8404:   }
1.270     brouard  8405:   else{
                   8406:     hstepm=estepm;   
                   8407:   }
                   8408:   if(estepm > stepm){ /* Yes every two year */
                   8409:     stepsize=2;
                   8410:   }
1.296     brouard  8411:   hstepm=hstepm/stepm;
1.126     brouard  8412: 
1.296     brouard  8413:   
                   8414:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8415:   /*                              fractional in yp1 *\/ */
                   8416:   /* aintmean=yp; */
                   8417:   /* yp2=modf((yp1*12),&yp); */
                   8418:   /* mintmean=yp; */
                   8419:   /* yp1=modf((yp2*30.5),&yp); */
                   8420:   /* jintmean=yp; */
                   8421:   /* if(jintmean==0) jintmean=1; */
                   8422:   /* if(mintmean==0) mintmean=1; */
1.126     brouard  8423: 
1.296     brouard  8424: 
                   8425:   /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */
                   8426:   /* date2dmy(dateprojd,&jprojd, &mprojd, &anprojd); */
                   8427:   /* date2dmy(dateprojf,&jprojf, &mprojf, &anprojf); */
1.227     brouard  8428:   i1=pow(2,cptcoveff);
1.126     brouard  8429:   if (cptcovn < 1){i1=1;}
                   8430:   
1.296     brouard  8431:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2); 
1.126     brouard  8432:   
                   8433:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8434:   
1.126     brouard  8435: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8436:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8437:   for(k=1; k<=i1;k++){
1.253     brouard  8438:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8439:       continue;
1.227     brouard  8440:     if(invalidvarcomb[k]){
                   8441:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8442:       continue;
                   8443:     }
                   8444:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8445:     for(j=1;j<=cptcoveff;j++) {
                   8446:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8447:     }
1.235     brouard  8448:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8449:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8450:     }
1.227     brouard  8451:     fprintf(ficresf," yearproj age");
                   8452:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8453:       for(i=1; i<=nlstate;i++)               
                   8454:        fprintf(ficresf," p%d%d",i,j);
                   8455:       fprintf(ficresf," wp.%d",j);
                   8456:     }
1.296     brouard  8457:     for (yearp=0; yearp<=(anprojf-anprojd);yearp +=stepsize) {
1.227     brouard  8458:       fprintf(ficresf,"\n");
1.296     brouard  8459:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jprojd,mprojd,anprojd+yearp);   
1.270     brouard  8460:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8461:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8462:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8463:        nhstepm = nhstepm/hstepm; 
                   8464:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8465:        oldm=oldms;savm=savms;
1.268     brouard  8466:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8467:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8468:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8469:        for (h=0; h<=nhstepm; h++){
                   8470:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8471:            break;
                   8472:          }
                   8473:        }
                   8474:        fprintf(ficresf,"\n");
                   8475:        for(j=1;j<=cptcoveff;j++) 
                   8476:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8477:        fprintf(ficresf,"%.f %.f ",anprojd+yearp,agec+h*hstepm/YEARM*stepm);
1.268     brouard  8478:        
                   8479:        for(j=1; j<=nlstate+ndeath;j++) {
                   8480:          ppij=0.;
                   8481:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8482:            if (mobilav>=1)
                   8483:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8484:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8485:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8486:            }
1.268     brouard  8487:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8488:          } /* end i */
                   8489:          fprintf(ficresf," %.3f", ppij);
                   8490:        }/* end j */
1.227     brouard  8491:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8492:       } /* end agec */
1.266     brouard  8493:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8494:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8495:     } /* end yearp */
                   8496:   } /* end  k */
1.219     brouard  8497:        
1.126     brouard  8498:   fclose(ficresf);
1.215     brouard  8499:   printf("End of Computing forecasting \n");
                   8500:   fprintf(ficlog,"End of Computing forecasting\n");
                   8501: 
1.126     brouard  8502: }
                   8503: 
1.269     brouard  8504: /************** Back Forecasting ******************/
1.296     brouard  8505:  /* void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
                   8506:  void prevbackforecast(char fileres[], double ***prevacurrent, double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8507:   /* back1, year, month, day of starting backprojection
1.267     brouard  8508:      agemin, agemax range of age
                   8509:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8510:      anback2 year of end of backprojection (same day and month as back1).
                   8511:      prevacurrent and prev are prevalences.
1.267     brouard  8512:   */
                   8513:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8514:   double agec; /* generic age */
1.302     brouard  8515:   double agelim, ppij, ppi, yp,yp1,yp2; /* ,jintmean,mintmean,aintmean;*/
1.267     brouard  8516:   double *popeffectif,*popcount;
                   8517:   double ***p3mat;
                   8518:   /* double ***mobaverage; */
                   8519:   char fileresfb[FILENAMELENGTH];
                   8520:  
1.268     brouard  8521:   agelim=AGEINF;
1.267     brouard  8522:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8523:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8524:      We still use firstpass and lastpass as another selection.
                   8525:   */
                   8526:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8527:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8528: 
                   8529:   /*Do we need to compute prevalence again?*/
                   8530: 
                   8531:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8532:   
                   8533:   strcpy(fileresfb,"FB_");
                   8534:   strcat(fileresfb,fileresu);
                   8535:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8536:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8537:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8538:   }
                   8539:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8540:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8541:   
                   8542:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8543:   
                   8544:    
                   8545:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8546:   if (stepm<=12) stepsize=1;
                   8547:   if(estepm < stepm){
                   8548:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8549:   }
1.270     brouard  8550:   else{
                   8551:     hstepm=estepm;   
                   8552:   }
                   8553:   if(estepm >= stepm){ /* Yes every two year */
                   8554:     stepsize=2;
                   8555:   }
1.267     brouard  8556:   
                   8557:   hstepm=hstepm/stepm;
1.296     brouard  8558:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8559:   /*                              fractional in yp1 *\/ */
                   8560:   /* aintmean=yp; */
                   8561:   /* yp2=modf((yp1*12),&yp); */
                   8562:   /* mintmean=yp; */
                   8563:   /* yp1=modf((yp2*30.5),&yp); */
                   8564:   /* jintmean=yp; */
                   8565:   /* if(jintmean==0) jintmean=1; */
                   8566:   /* if(mintmean==0) jintmean=1; */
1.267     brouard  8567:   
                   8568:   i1=pow(2,cptcoveff);
                   8569:   if (cptcovn < 1){i1=1;}
                   8570:   
1.296     brouard  8571:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
                   8572:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8573:   
                   8574:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8575:   
                   8576:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8577:   for(k=1; k<=i1;k++){
                   8578:     if(i1 != 1 && TKresult[nres]!= k)
                   8579:       continue;
                   8580:     if(invalidvarcomb[k]){
                   8581:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8582:       continue;
                   8583:     }
1.268     brouard  8584:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8585:     for(j=1;j<=cptcoveff;j++) {
                   8586:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8587:     }
                   8588:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8589:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8590:     }
                   8591:     fprintf(ficresfb," yearbproj age");
                   8592:     for(j=1; j<=nlstate+ndeath;j++){
                   8593:       for(i=1; i<=nlstate;i++)
1.268     brouard  8594:        fprintf(ficresfb," b%d%d",i,j);
                   8595:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8596:     }
1.296     brouard  8597:     for (yearp=0; yearp>=(anbackf-anbackd);yearp -=stepsize) {
1.267     brouard  8598:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8599:       fprintf(ficresfb,"\n");
1.296     brouard  8600:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jbackd,mbackd,anbackd+yearp);
1.273     brouard  8601:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8602:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8603:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8604:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8605:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8606:        nhstepm = nhstepm/hstepm;
                   8607:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8608:        oldm=oldms;savm=savms;
1.268     brouard  8609:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8610:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8611:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8612:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8613:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8614:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8615:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8616:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8617:            break;
                   8618:          }
                   8619:        }
                   8620:        fprintf(ficresfb,"\n");
                   8621:        for(j=1;j<=cptcoveff;j++)
                   8622:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8623:        fprintf(ficresfb,"%.f %.f ",anbackd+yearp,agec-h*hstepm/YEARM*stepm);
1.268     brouard  8624:        for(i=1; i<=nlstate+ndeath;i++) {
                   8625:          ppij=0.;ppi=0.;
                   8626:          for(j=1; j<=nlstate;j++) {
                   8627:            /* if (mobilav==1) */
1.269     brouard  8628:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8629:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8630:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8631:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8632:              /* else { */
                   8633:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8634:              /* } */
1.268     brouard  8635:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8636:          } /* end j */
                   8637:          if(ppi <0.99){
                   8638:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8639:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8640:          }
                   8641:          fprintf(ficresfb," %.3f", ppij);
                   8642:        }/* end j */
1.267     brouard  8643:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8644:       } /* end agec */
                   8645:     } /* end yearp */
                   8646:   } /* end k */
1.217     brouard  8647:   
1.267     brouard  8648:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8649:   
1.267     brouard  8650:   fclose(ficresfb);
                   8651:   printf("End of Computing Back forecasting \n");
                   8652:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8653:        
1.267     brouard  8654: }
1.217     brouard  8655: 
1.269     brouard  8656: /* Variance of prevalence limit: varprlim */
                   8657:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8658:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8659:  
                   8660:    char fileresvpl[FILENAMELENGTH];  
                   8661:    FILE *ficresvpl;
                   8662:    double **oldm, **savm;
                   8663:    double **varpl; /* Variances of prevalence limits by age */   
                   8664:    int i1, k, nres, j ;
                   8665:    
                   8666:     strcpy(fileresvpl,"VPL_");
                   8667:     strcat(fileresvpl,fileresu);
                   8668:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8669:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8670:       exit(0);
                   8671:     }
1.288     brouard  8672:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8673:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8674:     
                   8675:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8676:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8677:     
                   8678:     i1=pow(2,cptcoveff);
                   8679:     if (cptcovn < 1){i1=1;}
                   8680: 
                   8681:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8682:     for(k=1; k<=i1;k++){
                   8683:       if(i1 != 1 && TKresult[nres]!= k)
                   8684:        continue;
                   8685:       fprintf(ficresvpl,"\n#****** ");
                   8686:       printf("\n#****** ");
                   8687:       fprintf(ficlog,"\n#****** ");
                   8688:       for(j=1;j<=cptcoveff;j++) {
                   8689:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8690:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8691:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8692:       }
                   8693:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8694:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8695:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8696:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8697:       }        
                   8698:       fprintf(ficresvpl,"******\n");
                   8699:       printf("******\n");
                   8700:       fprintf(ficlog,"******\n");
                   8701:       
                   8702:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8703:       oldm=oldms;savm=savms;
                   8704:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8705:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8706:       /*}*/
                   8707:     }
                   8708:     
                   8709:     fclose(ficresvpl);
1.288     brouard  8710:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   8711:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  8712: 
                   8713:  }
                   8714: /* Variance of back prevalence: varbprlim */
                   8715:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8716:       /*------- Variance of back (stable) prevalence------*/
                   8717: 
                   8718:    char fileresvbl[FILENAMELENGTH];  
                   8719:    FILE  *ficresvbl;
                   8720: 
                   8721:    double **oldm, **savm;
                   8722:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8723:    int i1, k, nres, j ;
                   8724: 
                   8725:    strcpy(fileresvbl,"VBL_");
                   8726:    strcat(fileresvbl,fileresu);
                   8727:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8728:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8729:      exit(0);
                   8730:    }
                   8731:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8732:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8733:    
                   8734:    
                   8735:    i1=pow(2,cptcoveff);
                   8736:    if (cptcovn < 1){i1=1;}
                   8737:    
                   8738:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8739:      for(k=1; k<=i1;k++){
                   8740:        if(i1 != 1 && TKresult[nres]!= k)
                   8741:         continue;
                   8742:        fprintf(ficresvbl,"\n#****** ");
                   8743:        printf("\n#****** ");
                   8744:        fprintf(ficlog,"\n#****** ");
                   8745:        for(j=1;j<=cptcoveff;j++) {
                   8746:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8747:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8748:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8749:        }
                   8750:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8751:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8752:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8753:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8754:        }
                   8755:        fprintf(ficresvbl,"******\n");
                   8756:        printf("******\n");
                   8757:        fprintf(ficlog,"******\n");
                   8758:        
                   8759:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8760:        oldm=oldms;savm=savms;
                   8761:        
                   8762:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8763:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8764:        /*}*/
                   8765:      }
                   8766:    
                   8767:    fclose(ficresvbl);
                   8768:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8769:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8770: 
                   8771:  } /* End of varbprlim */
                   8772: 
1.126     brouard  8773: /************** Forecasting *****not tested NB*************/
1.227     brouard  8774: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8775:   
1.227     brouard  8776: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8777: /*   int *popage; */
                   8778: /*   double calagedatem, agelim, kk1, kk2; */
                   8779: /*   double *popeffectif,*popcount; */
                   8780: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8781: /*   /\* double ***mobaverage; *\/ */
                   8782: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8783: 
1.227     brouard  8784: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8785: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8786: /*   agelim=AGESUP; */
                   8787: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8788:   
1.227     brouard  8789: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8790:   
                   8791:   
1.227     brouard  8792: /*   strcpy(filerespop,"POP_");  */
                   8793: /*   strcat(filerespop,fileresu); */
                   8794: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8795: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8796: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8797: /*   } */
                   8798: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8799: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8800: 
1.227     brouard  8801: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8802: 
1.227     brouard  8803: /*   /\* if (mobilav!=0) { *\/ */
                   8804: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8805: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8806: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8807: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8808: /*   /\*   } *\/ */
                   8809: /*   /\* } *\/ */
1.126     brouard  8810: 
1.227     brouard  8811: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8812: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8813:   
1.227     brouard  8814: /*   agelim=AGESUP; */
1.126     brouard  8815:   
1.227     brouard  8816: /*   hstepm=1; */
                   8817: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8818:        
1.227     brouard  8819: /*   if (popforecast==1) { */
                   8820: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8821: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8822: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8823: /*     }  */
                   8824: /*     popage=ivector(0,AGESUP); */
                   8825: /*     popeffectif=vector(0,AGESUP); */
                   8826: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8827:     
1.227     brouard  8828: /*     i=1;    */
                   8829: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8830:     
1.227     brouard  8831: /*     imx=i; */
                   8832: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8833: /*   } */
1.218     brouard  8834:   
1.227     brouard  8835: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8836: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8837: /*       k=k+1; */
                   8838: /*       fprintf(ficrespop,"\n#******"); */
                   8839: /*       for(j=1;j<=cptcoveff;j++) { */
                   8840: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8841: /*       } */
                   8842: /*       fprintf(ficrespop,"******\n"); */
                   8843: /*       fprintf(ficrespop,"# Age"); */
                   8844: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8845: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8846:       
1.227     brouard  8847: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8848: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8849:        
1.227     brouard  8850: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8851: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8852: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8853:          
1.227     brouard  8854: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8855: /*       oldm=oldms;savm=savms; */
                   8856: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8857:          
1.227     brouard  8858: /*       for (h=0; h<=nhstepm; h++){ */
                   8859: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8860: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8861: /*         }  */
                   8862: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8863: /*           kk1=0.;kk2=0; */
                   8864: /*           for(i=1; i<=nlstate;i++) {               */
                   8865: /*             if (mobilav==1)  */
                   8866: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8867: /*             else { */
                   8868: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8869: /*             } */
                   8870: /*           } */
                   8871: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8872: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8873: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8874: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8875: /*           } */
                   8876: /*         } */
                   8877: /*         for(i=1; i<=nlstate;i++){ */
                   8878: /*           kk1=0.; */
                   8879: /*           for(j=1; j<=nlstate;j++){ */
                   8880: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8881: /*           } */
                   8882: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8883: /*         } */
1.218     brouard  8884:            
1.227     brouard  8885: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8886: /*           for(j=1; j<=nlstate;j++)  */
                   8887: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8888: /*       } */
                   8889: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8890: /*     } */
                   8891: /*       } */
1.218     brouard  8892:       
1.227     brouard  8893: /*       /\******\/ */
1.218     brouard  8894:       
1.227     brouard  8895: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8896: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8897: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8898: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8899: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8900:          
1.227     brouard  8901: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8902: /*       oldm=oldms;savm=savms; */
                   8903: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8904: /*       for (h=0; h<=nhstepm; h++){ */
                   8905: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8906: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8907: /*         }  */
                   8908: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8909: /*           kk1=0.;kk2=0; */
                   8910: /*           for(i=1; i<=nlstate;i++) {               */
                   8911: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8912: /*           } */
                   8913: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8914: /*         } */
                   8915: /*       } */
                   8916: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8917: /*     } */
                   8918: /*       } */
                   8919: /*     }  */
                   8920: /*   } */
1.218     brouard  8921:   
1.227     brouard  8922: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8923:   
1.227     brouard  8924: /*   if (popforecast==1) { */
                   8925: /*     free_ivector(popage,0,AGESUP); */
                   8926: /*     free_vector(popeffectif,0,AGESUP); */
                   8927: /*     free_vector(popcount,0,AGESUP); */
                   8928: /*   } */
                   8929: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8930: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8931: /*   fclose(ficrespop); */
                   8932: /* } /\* End of popforecast *\/ */
1.218     brouard  8933:  
1.126     brouard  8934: int fileappend(FILE *fichier, char *optionfich)
                   8935: {
                   8936:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8937:     printf("Problem with file: %s\n", optionfich);
                   8938:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8939:     return (0);
                   8940:   }
                   8941:   fflush(fichier);
                   8942:   return (1);
                   8943: }
                   8944: 
                   8945: 
                   8946: /**************** function prwizard **********************/
                   8947: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8948: {
                   8949: 
                   8950:   /* Wizard to print covariance matrix template */
                   8951: 
1.164     brouard  8952:   char ca[32], cb[32];
                   8953:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8954:   int numlinepar;
                   8955: 
                   8956:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8957:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8958:   for(i=1; i <=nlstate; i++){
                   8959:     jj=0;
                   8960:     for(j=1; j <=nlstate+ndeath; j++){
                   8961:       if(j==i) continue;
                   8962:       jj++;
                   8963:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8964:       printf("%1d%1d",i,j);
                   8965:       fprintf(ficparo,"%1d%1d",i,j);
                   8966:       for(k=1; k<=ncovmodel;k++){
                   8967:        /*        printf(" %lf",param[i][j][k]); */
                   8968:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8969:        printf(" 0.");
                   8970:        fprintf(ficparo," 0.");
                   8971:       }
                   8972:       printf("\n");
                   8973:       fprintf(ficparo,"\n");
                   8974:     }
                   8975:   }
                   8976:   printf("# Scales (for hessian or gradient estimation)\n");
                   8977:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8978:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8979:   for(i=1; i <=nlstate; i++){
                   8980:     jj=0;
                   8981:     for(j=1; j <=nlstate+ndeath; j++){
                   8982:       if(j==i) continue;
                   8983:       jj++;
                   8984:       fprintf(ficparo,"%1d%1d",i,j);
                   8985:       printf("%1d%1d",i,j);
                   8986:       fflush(stdout);
                   8987:       for(k=1; k<=ncovmodel;k++){
                   8988:        /*      printf(" %le",delti3[i][j][k]); */
                   8989:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   8990:        printf(" 0.");
                   8991:        fprintf(ficparo," 0.");
                   8992:       }
                   8993:       numlinepar++;
                   8994:       printf("\n");
                   8995:       fprintf(ficparo,"\n");
                   8996:     }
                   8997:   }
                   8998:   printf("# Covariance matrix\n");
                   8999: /* # 121 Var(a12)\n\ */
                   9000: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9001: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   9002: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   9003: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   9004: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   9005: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   9006: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   9007:   fflush(stdout);
                   9008:   fprintf(ficparo,"# Covariance matrix\n");
                   9009:   /* # 121 Var(a12)\n\ */
                   9010:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9011:   /* #   ...\n\ */
                   9012:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   9013:   
                   9014:   for(itimes=1;itimes<=2;itimes++){
                   9015:     jj=0;
                   9016:     for(i=1; i <=nlstate; i++){
                   9017:       for(j=1; j <=nlstate+ndeath; j++){
                   9018:        if(j==i) continue;
                   9019:        for(k=1; k<=ncovmodel;k++){
                   9020:          jj++;
                   9021:          ca[0]= k+'a'-1;ca[1]='\0';
                   9022:          if(itimes==1){
                   9023:            printf("#%1d%1d%d",i,j,k);
                   9024:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   9025:          }else{
                   9026:            printf("%1d%1d%d",i,j,k);
                   9027:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   9028:            /*  printf(" %.5le",matcov[i][j]); */
                   9029:          }
                   9030:          ll=0;
                   9031:          for(li=1;li <=nlstate; li++){
                   9032:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   9033:              if(lj==li) continue;
                   9034:              for(lk=1;lk<=ncovmodel;lk++){
                   9035:                ll++;
                   9036:                if(ll<=jj){
                   9037:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   9038:                  if(ll<jj){
                   9039:                    if(itimes==1){
                   9040:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9041:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9042:                    }else{
                   9043:                      printf(" 0.");
                   9044:                      fprintf(ficparo," 0.");
                   9045:                    }
                   9046:                  }else{
                   9047:                    if(itimes==1){
                   9048:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   9049:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   9050:                    }else{
                   9051:                      printf(" 0.");
                   9052:                      fprintf(ficparo," 0.");
                   9053:                    }
                   9054:                  }
                   9055:                }
                   9056:              } /* end lk */
                   9057:            } /* end lj */
                   9058:          } /* end li */
                   9059:          printf("\n");
                   9060:          fprintf(ficparo,"\n");
                   9061:          numlinepar++;
                   9062:        } /* end k*/
                   9063:       } /*end j */
                   9064:     } /* end i */
                   9065:   } /* end itimes */
                   9066: 
                   9067: } /* end of prwizard */
                   9068: /******************* Gompertz Likelihood ******************************/
                   9069: double gompertz(double x[])
                   9070: { 
1.302     brouard  9071:   double A=0.0,B=0.,L=0.0,sump=0.,num=0.;
1.126     brouard  9072:   int i,n=0; /* n is the size of the sample */
                   9073: 
1.220     brouard  9074:   for (i=1;i<=imx ; i++) {
1.126     brouard  9075:     sump=sump+weight[i];
                   9076:     /*    sump=sump+1;*/
                   9077:     num=num+1;
                   9078:   }
1.302     brouard  9079:   L=0.0;
                   9080:   /* agegomp=AGEGOMP; */
1.126     brouard  9081:   /* for (i=0; i<=imx; i++) 
                   9082:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9083: 
1.302     brouard  9084:   for (i=1;i<=imx ; i++) {
                   9085:     /* mu(a)=mu(agecomp)*exp(teta*(age-agegomp))
                   9086:        mu(a)=x[1]*exp(x[2]*(age-agegomp)); x[1] and x[2] are per year.
                   9087:      * L= Product mu(agedeces)exp(-\int_ageexam^agedc mu(u) du ) for a death between agedc (in month) 
                   9088:      *   and agedc +1 month, cens[i]=0: log(x[1]/YEARM)
                   9089:      * +
                   9090:      * exp(-\int_ageexam^agecens mu(u) du ) when censored, cens[i]=1
                   9091:      */
                   9092:      if (wav[i] > 1 || agedc[i] < AGESUP) {
                   9093:        if (cens[i] == 1){
                   9094:         A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9095:        } else if (cens[i] == 0){
1.126     brouard  9096:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
1.302     brouard  9097:          +log(x[1]/YEARM) +x[2]*(agedc[i]-agegomp)+log(YEARM);
                   9098:       } else
                   9099:         printf("Gompertz cens[%d] neither 1 nor 0\n",i);
1.126     brouard  9100:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
1.302     brouard  9101:        L=L+A*weight[i];
1.126     brouard  9102:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
1.302     brouard  9103:      }
                   9104:   }
1.126     brouard  9105: 
1.302     brouard  9106:   /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
1.126     brouard  9107:  
                   9108:   return -2*L*num/sump;
                   9109: }
                   9110: 
1.136     brouard  9111: #ifdef GSL
                   9112: /******************* Gompertz_f Likelihood ******************************/
                   9113: double gompertz_f(const gsl_vector *v, void *params)
                   9114: { 
1.302     brouard  9115:   double A=0.,B=0.,LL=0.0,sump=0.,num=0.;
1.136     brouard  9116:   double *x= (double *) v->data;
                   9117:   int i,n=0; /* n is the size of the sample */
                   9118: 
                   9119:   for (i=0;i<=imx-1 ; i++) {
                   9120:     sump=sump+weight[i];
                   9121:     /*    sump=sump+1;*/
                   9122:     num=num+1;
                   9123:   }
                   9124:  
                   9125:  
                   9126:   /* for (i=0; i<=imx; i++) 
                   9127:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9128:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9129:   for (i=1;i<=imx ; i++)
                   9130:     {
                   9131:       if (cens[i] == 1 && wav[i]>1)
                   9132:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9133:       
                   9134:       if (cens[i] == 0 && wav[i]>1)
                   9135:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9136:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9137:       
                   9138:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9139:       if (wav[i] > 1 ) { /* ??? */
                   9140:        LL=LL+A*weight[i];
                   9141:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9142:       }
                   9143:     }
                   9144: 
                   9145:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9146:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9147:  
                   9148:   return -2*LL*num/sump;
                   9149: }
                   9150: #endif
                   9151: 
1.126     brouard  9152: /******************* Printing html file ***********/
1.201     brouard  9153: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9154:                  int lastpass, int stepm, int weightopt, char model[],\
                   9155:                  int imx,  double p[],double **matcov,double agemortsup){
                   9156:   int i,k;
                   9157: 
                   9158:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9159:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9160:   for (i=1;i<=2;i++) 
                   9161:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9162:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9163:   fprintf(fichtm,"</ul>");
                   9164: 
                   9165: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9166: 
                   9167:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9168: 
                   9169:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9170:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9171: 
                   9172:  
                   9173:   fflush(fichtm);
                   9174: }
                   9175: 
                   9176: /******************* Gnuplot file **************/
1.201     brouard  9177: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9178: 
                   9179:   char dirfileres[132],optfileres[132];
1.164     brouard  9180: 
1.126     brouard  9181:   int ng;
                   9182: 
                   9183: 
                   9184:   /*#ifdef windows */
                   9185:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9186:     /*#endif */
                   9187: 
                   9188: 
                   9189:   strcpy(dirfileres,optionfilefiname);
                   9190:   strcpy(optfileres,"vpl");
1.199     brouard  9191:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9192:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9193:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9194:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9195:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9196: 
                   9197: } 
                   9198: 
1.136     brouard  9199: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9200: {
1.126     brouard  9201: 
1.136     brouard  9202:   /*-------- data file ----------*/
                   9203:   FILE *fic;
                   9204:   char dummy[]="                         ";
1.240     brouard  9205:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9206:   int lstra;
1.136     brouard  9207:   int linei, month, year,iout;
1.302     brouard  9208:   int noffset=0; /* This is the offset if BOM data file */
1.136     brouard  9209:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9210:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9211:   char *stratrunc;
1.223     brouard  9212: 
1.240     brouard  9213:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9214:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9215: 
1.240     brouard  9216:   for(v=1; v <=ncovcol;v++){
                   9217:     DummyV[v]=0;
                   9218:     FixedV[v]=0;
                   9219:   }
                   9220:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9221:     DummyV[v]=1;
                   9222:     FixedV[v]=0;
                   9223:   }
                   9224:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9225:     DummyV[v]=0;
                   9226:     FixedV[v]=1;
                   9227:   }
                   9228:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9229:     DummyV[v]=1;
                   9230:     FixedV[v]=1;
                   9231:   }
                   9232:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9233:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9234:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9235:   }
1.126     brouard  9236: 
1.136     brouard  9237:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9238:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9239:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9240:   }
1.126     brouard  9241: 
1.302     brouard  9242:     /* Is it a BOM UTF-8 Windows file? */
                   9243:   /* First data line */
                   9244:   linei=0;
                   9245:   while(fgets(line, MAXLINE, fic)) {
                   9246:     noffset=0;
                   9247:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   9248:     {
                   9249:       noffset=noffset+3;
                   9250:       printf("# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);fflush(stdout);
                   9251:       fprintf(ficlog,"# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);
                   9252:       fflush(ficlog); return 1;
                   9253:     }
                   9254:     /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   9255:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
                   9256:     {
                   9257:       noffset=noffset+2;
1.304   ! brouard  9258:       printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
        !          9259:       fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9260:       fflush(ficlog); return 1;
                   9261:     }
                   9262:     else if( line[0] == 0 && line[1] == 0)
                   9263:     {
                   9264:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   9265:        noffset=noffset+4;
1.304   ! brouard  9266:        printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
        !          9267:        fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9268:        fflush(ficlog); return 1;
                   9269:       }
                   9270:     } else{
                   9271:       ;/*printf(" Not a BOM file\n");*/
                   9272:     }
                   9273:         /* If line starts with a # it is a comment */
                   9274:     if (line[noffset] == '#') {
                   9275:       linei=linei+1;
                   9276:       break;
                   9277:     }else{
                   9278:       break;
                   9279:     }
                   9280:   }
                   9281:   fclose(fic);
                   9282:   if((fic=fopen(datafile,"r"))==NULL)    {
                   9283:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9284:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
                   9285:   }
                   9286:   /* Not a Bom file */
                   9287:   
1.136     brouard  9288:   i=1;
                   9289:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9290:     linei=linei+1;
                   9291:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9292:       if(line[j] == '\t')
                   9293:        line[j] = ' ';
                   9294:     }
                   9295:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9296:       ;
                   9297:     };
                   9298:     line[j+1]=0;  /* Trims blanks at end of line */
                   9299:     if(line[0]=='#'){
                   9300:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9301:       printf("Comment line\n%s\n",line);
                   9302:       continue;
                   9303:     }
                   9304:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9305:     strcpy(line, linetmp);
1.223     brouard  9306:     
                   9307:     /* Loops on waves */
                   9308:     for (j=maxwav;j>=1;j--){
                   9309:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9310:        cutv(stra, strb, line, ' '); 
                   9311:        if(strb[0]=='.') { /* Missing value */
                   9312:          lval=-1;
                   9313:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9314:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9315:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9316:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9317:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9318:            return 1;
                   9319:          }
                   9320:        }else{
                   9321:          errno=0;
                   9322:          /* what_kind_of_number(strb); */
                   9323:          dval=strtod(strb,&endptr); 
                   9324:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9325:          /* if(strb != endptr && *endptr == '\0') */
                   9326:          /*    dval=dlval; */
                   9327:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9328:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9329:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9330:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9331:            return 1;
                   9332:          }
                   9333:          cotqvar[j][iv][i]=dval; 
                   9334:          cotvar[j][ntv+iv][i]=dval; 
                   9335:        }
                   9336:        strcpy(line,stra);
1.223     brouard  9337:       }/* end loop ntqv */
1.225     brouard  9338:       
1.223     brouard  9339:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9340:        cutv(stra, strb, line, ' '); 
                   9341:        if(strb[0]=='.') { /* Missing value */
                   9342:          lval=-1;
                   9343:        }else{
                   9344:          errno=0;
                   9345:          lval=strtol(strb,&endptr,10); 
                   9346:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9347:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9348:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9349:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9350:            return 1;
                   9351:          }
                   9352:        }
                   9353:        if(lval <-1 || lval >1){
                   9354:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9355:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9356:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9357:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9358:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9359:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9360:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9361:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9362:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9363:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9364:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9365:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9366:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9367:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9368:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9369:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9370:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9371:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9372:          return 1;
                   9373:        }
                   9374:        cotvar[j][iv][i]=(double)(lval);
                   9375:        strcpy(line,stra);
1.223     brouard  9376:       }/* end loop ntv */
1.225     brouard  9377:       
1.223     brouard  9378:       /* Statuses  at wave */
1.137     brouard  9379:       cutv(stra, strb, line, ' '); 
1.223     brouard  9380:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9381:        lval=-1;
1.136     brouard  9382:       }else{
1.238     brouard  9383:        errno=0;
                   9384:        lval=strtol(strb,&endptr,10); 
                   9385:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9386:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9387:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9388:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9389:          return 1;
                   9390:        }
1.136     brouard  9391:       }
1.225     brouard  9392:       
1.136     brouard  9393:       s[j][i]=lval;
1.225     brouard  9394:       
1.223     brouard  9395:       /* Date of Interview */
1.136     brouard  9396:       strcpy(line,stra);
                   9397:       cutv(stra, strb,line,' ');
1.169     brouard  9398:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9399:       }
1.169     brouard  9400:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9401:        month=99;
                   9402:        year=9999;
1.136     brouard  9403:       }else{
1.225     brouard  9404:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9405:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9406:        return 1;
1.136     brouard  9407:       }
                   9408:       anint[j][i]= (double) year; 
1.302     brouard  9409:       mint[j][i]= (double)month;
                   9410:       /* if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){ */
                   9411:       /*       printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9412:       /*       fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9413:       /* } */
1.136     brouard  9414:       strcpy(line,stra);
1.223     brouard  9415:     } /* End loop on waves */
1.225     brouard  9416:     
1.223     brouard  9417:     /* Date of death */
1.136     brouard  9418:     cutv(stra, strb,line,' '); 
1.169     brouard  9419:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9420:     }
1.169     brouard  9421:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9422:       month=99;
                   9423:       year=9999;
                   9424:     }else{
1.141     brouard  9425:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9426:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9427:       return 1;
1.136     brouard  9428:     }
                   9429:     andc[i]=(double) year; 
                   9430:     moisdc[i]=(double) month; 
                   9431:     strcpy(line,stra);
                   9432:     
1.223     brouard  9433:     /* Date of birth */
1.136     brouard  9434:     cutv(stra, strb,line,' '); 
1.169     brouard  9435:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9436:     }
1.169     brouard  9437:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9438:       month=99;
                   9439:       year=9999;
                   9440:     }else{
1.141     brouard  9441:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9442:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9443:       return 1;
1.136     brouard  9444:     }
                   9445:     if (year==9999) {
1.141     brouard  9446:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9447:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9448:       return 1;
                   9449:       
1.136     brouard  9450:     }
                   9451:     annais[i]=(double)(year);
1.302     brouard  9452:     moisnais[i]=(double)(month);
                   9453:     for (j=1;j<=maxwav;j++){
                   9454:       if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){
                   9455:        printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j,(int)moisnais[i],(int)annais[i]);
                   9456:        fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j, (int)moisnais[i],(int)annais[i]);
                   9457:       }
                   9458:     }
                   9459: 
1.136     brouard  9460:     strcpy(line,stra);
1.225     brouard  9461:     
1.223     brouard  9462:     /* Sample weight */
1.136     brouard  9463:     cutv(stra, strb,line,' '); 
                   9464:     errno=0;
                   9465:     dval=strtod(strb,&endptr); 
                   9466:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9467:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9468:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9469:       fflush(ficlog);
                   9470:       return 1;
                   9471:     }
                   9472:     weight[i]=dval; 
                   9473:     strcpy(line,stra);
1.225     brouard  9474:     
1.223     brouard  9475:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9476:       cutv(stra, strb, line, ' '); 
                   9477:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9478:        lval=-1;
1.223     brouard  9479:       }else{
1.225     brouard  9480:        errno=0;
                   9481:        /* what_kind_of_number(strb); */
                   9482:        dval=strtod(strb,&endptr);
                   9483:        /* if(strb != endptr && *endptr == '\0') */
                   9484:        /*   dval=dlval; */
                   9485:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9486:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9487:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9488:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9489:          return 1;
                   9490:        }
                   9491:        coqvar[iv][i]=dval; 
1.226     brouard  9492:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9493:       }
                   9494:       strcpy(line,stra);
                   9495:     }/* end loop nqv */
1.136     brouard  9496:     
1.223     brouard  9497:     /* Covariate values */
1.136     brouard  9498:     for (j=ncovcol;j>=1;j--){
                   9499:       cutv(stra, strb,line,' '); 
1.223     brouard  9500:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9501:        lval=-1;
1.136     brouard  9502:       }else{
1.225     brouard  9503:        errno=0;
                   9504:        lval=strtol(strb,&endptr,10); 
                   9505:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9506:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9507:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9508:          return 1;
                   9509:        }
1.136     brouard  9510:       }
                   9511:       if(lval <-1 || lval >1){
1.225     brouard  9512:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9513:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9514:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9515:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9516:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9517:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9518:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9519:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9520:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9521:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9522:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9523:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9524:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9525:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9526:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9527:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9528:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9529:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9530:        return 1;
1.136     brouard  9531:       }
                   9532:       covar[j][i]=(double)(lval);
                   9533:       strcpy(line,stra);
                   9534:     }  
                   9535:     lstra=strlen(stra);
1.225     brouard  9536:     
1.136     brouard  9537:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9538:       stratrunc = &(stra[lstra-9]);
                   9539:       num[i]=atol(stratrunc);
                   9540:     }
                   9541:     else
                   9542:       num[i]=atol(stra);
                   9543:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9544:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9545:     
                   9546:     i=i+1;
                   9547:   } /* End loop reading  data */
1.225     brouard  9548:   
1.136     brouard  9549:   *imax=i-1; /* Number of individuals */
                   9550:   fclose(fic);
1.225     brouard  9551:   
1.136     brouard  9552:   return (0);
1.164     brouard  9553:   /* endread: */
1.225     brouard  9554:   printf("Exiting readdata: ");
                   9555:   fclose(fic);
                   9556:   return (1);
1.223     brouard  9557: }
1.126     brouard  9558: 
1.234     brouard  9559: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9560:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9561:   while (*p2 == ' ')
1.234     brouard  9562:     p2++; 
                   9563:   /* while ((*p1++ = *p2++) !=0) */
                   9564:   /*   ; */
                   9565:   /* do */
                   9566:   /*   while (*p2 == ' ') */
                   9567:   /*     p2++; */
                   9568:   /* while (*p1++ == *p2++); */
                   9569:   *stri=p2; 
1.145     brouard  9570: }
                   9571: 
1.235     brouard  9572: int decoderesult ( char resultline[], int nres)
1.230     brouard  9573: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9574: {
1.235     brouard  9575:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9576:   char resultsav[MAXLINE];
1.234     brouard  9577:   int resultmodel[MAXLINE];
                   9578:   int modelresult[MAXLINE];
1.230     brouard  9579:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9580: 
1.234     brouard  9581:   removefirstspace(&resultline);
1.233     brouard  9582:   printf("decoderesult:%s\n",resultline);
1.230     brouard  9583: 
                   9584:   if (strstr(resultline,"v") !=0){
                   9585:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9586:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9587:     return 1;
                   9588:   }
                   9589:   trimbb(resultsav, resultline);
                   9590:   if (strlen(resultsav) >1){
                   9591:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9592:   }
1.253     brouard  9593:   if(j == 0){ /* Resultline but no = */
                   9594:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9595:     return (0);
                   9596:   }
                   9597:     
1.234     brouard  9598:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9599:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9600:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9601:   }
                   9602:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9603:     if(nbocc(resultsav,'=') >1){
                   9604:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9605:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9606:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9607:     }else
                   9608:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9609:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9610:     
1.230     brouard  9611:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9612:     Tvarsel[k]=atoi(strc);
                   9613:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9614:     /* cptcovsel++;     */
                   9615:     if (nbocc(stra,'=') >0)
                   9616:       strcpy(resultsav,stra); /* and analyzes it */
                   9617:   }
1.235     brouard  9618:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9619:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9620:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9621:       match=0;
1.236     brouard  9622:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9623:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9624:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9625:          match=1;
                   9626:          break;
                   9627:        }
                   9628:       }
                   9629:       if(match == 0){
                   9630:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9631:       }
                   9632:     }
                   9633:   }
1.235     brouard  9634:   /* Checking for missing or useless values in comparison of current model needs */
                   9635:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9636:     match=0;
1.235     brouard  9637:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9638:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9639:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9640:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9641:          ++match;
                   9642:        }
                   9643:       }
                   9644:     }
                   9645:     if(match == 0){
                   9646:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9647:     }else if(match > 1){
                   9648:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9649:     }
                   9650:   }
1.235     brouard  9651:       
1.234     brouard  9652:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9653:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9654:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9655:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9656:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9657:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9658:   /*    1 0 0 0 */
                   9659:   /*    2 1 0 0 */
                   9660:   /*    3 0 1 0 */ 
                   9661:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9662:   /*    5 0 0 1 */
                   9663:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9664:   /*    7 0 1 1 */
                   9665:   /*    8 1 1 1 */
1.237     brouard  9666:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9667:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9668:   /* V5*age V5 known which value for nres?  */
                   9669:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9670:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9671:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9672:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9673:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9674:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9675:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9676:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9677:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9678:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9679:       k4++;;
                   9680:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9681:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9682:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9683:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9684:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9685:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9686:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9687:       k4q++;;
                   9688:     }
                   9689:   }
1.234     brouard  9690:   
1.235     brouard  9691:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9692:   return (0);
                   9693: }
1.235     brouard  9694: 
1.230     brouard  9695: int decodemodel( char model[], int lastobs)
                   9696:  /**< This routine decodes the model and returns:
1.224     brouard  9697:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9698:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9699:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9700:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9701:        * - cptcovage number of covariates with age*products =2
                   9702:        * - cptcovs number of simple covariates
                   9703:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9704:        *     which is a new column after the 9 (ncovcol) variables. 
                   9705:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9706:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9707:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9708:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9709:        */
1.136     brouard  9710: {
1.238     brouard  9711:   int i, j, k, ks, v;
1.227     brouard  9712:   int  j1, k1, k2, k3, k4;
1.136     brouard  9713:   char modelsav[80];
1.145     brouard  9714:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9715:   char *strpt;
1.136     brouard  9716: 
1.145     brouard  9717:   /*removespace(model);*/
1.136     brouard  9718:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9719:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9720:     if (strstr(model,"AGE") !=0){
1.192     brouard  9721:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9722:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9723:       return 1;
                   9724:     }
1.141     brouard  9725:     if (strstr(model,"v") !=0){
                   9726:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9727:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9728:       return 1;
                   9729:     }
1.187     brouard  9730:     strcpy(modelsav,model); 
                   9731:     if ((strpt=strstr(model,"age*age")) !=0){
                   9732:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9733:       if(strpt != model){
1.234     brouard  9734:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9735:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9736:  corresponding column of parameters.\n",model);
1.234     brouard  9737:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9738:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9739:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9740:        return 1;
1.225     brouard  9741:       }
1.187     brouard  9742:       nagesqr=1;
                   9743:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9744:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9745:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9746:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9747:       else 
1.234     brouard  9748:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9749:     }else
                   9750:       nagesqr=0;
                   9751:     if (strlen(modelsav) >1){
                   9752:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9753:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9754:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9755:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9756:                     * cst, age and age*age 
                   9757:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9758:       /* including age products which are counted in cptcovage.
                   9759:        * but the covariates which are products must be treated 
                   9760:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9761:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9762:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9763:       
                   9764:       
1.187     brouard  9765:       /*   Design
                   9766:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9767:        *  <          ncovcol=8                >
                   9768:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9769:        *   k=  1    2      3       4     5       6      7        8
                   9770:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9771:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9772:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9773:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9774:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9775:        *  Tage[++cptcovage]=k
                   9776:        *       if products, new covar are created after ncovcol with k1
                   9777:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9778:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9779:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9780:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9781:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9782:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9783:        *  <          ncovcol=8                >
                   9784:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9785:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9786:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9787:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9788:        * p Tprod[1]@2={                         6, 5}
                   9789:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9790:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9791:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9792:        *How to reorganize?
                   9793:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9794:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9795:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9796:        * Struct []
                   9797:        */
1.225     brouard  9798:       
1.187     brouard  9799:       /* This loop fills the array Tvar from the string 'model'.*/
                   9800:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9801:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9802:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9803:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9804:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9805:       /*       k=1 Tvar[1]=2 (from V2) */
                   9806:       /*       k=5 Tvar[5] */
                   9807:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9808:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9809:       /*       } */
1.198     brouard  9810:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9811:       /*
                   9812:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9813:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9814:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9815:       }
1.187     brouard  9816:       cptcovage=0;
                   9817:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9818:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9819:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9820:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9821:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9822:        /*scanf("%d",i);*/
                   9823:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9824:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9825:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9826:            /* covar is not filled and then is empty */
                   9827:            cptcovprod--;
                   9828:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9829:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9830:            Typevar[k]=1;  /* 1 for age product */
                   9831:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9832:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9833:            /*printf("stre=%s ", stre);*/
                   9834:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9835:            cptcovprod--;
                   9836:            cutl(stre,strb,strc,'V');
                   9837:            Tvar[k]=atoi(stre);
                   9838:            Typevar[k]=1;  /* 1 for age product */
                   9839:            cptcovage++;
                   9840:            Tage[cptcovage]=k;
                   9841:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9842:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9843:            cptcovn++;
                   9844:            cptcovprodnoage++;k1++;
                   9845:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9846:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9847:                                                because this model-covariate is a construction we invent a new column
                   9848:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9849:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9850:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9851:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9852:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9853:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9854:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9855:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9856:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9857:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9858:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9859:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9860:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9861:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9862:            for (i=1; i<=lastobs;i++){
                   9863:              /* Computes the new covariate which is a product of
                   9864:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9865:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9866:            }
                   9867:          } /* End age is not in the model */
                   9868:        } /* End if model includes a product */
                   9869:        else { /* no more sum */
                   9870:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9871:          /*  scanf("%d",i);*/
                   9872:          cutl(strd,strc,strb,'V');
                   9873:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9874:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9875:          Tvar[k]=atoi(strd);
                   9876:          Typevar[k]=0;  /* 0 for simple covariates */
                   9877:        }
                   9878:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9879:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9880:                                  scanf("%d",i);*/
1.187     brouard  9881:       } /* end of loop + on total covariates */
                   9882:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9883:   } /* end if strlen(model == 0) */
1.136     brouard  9884:   
                   9885:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9886:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9887:   
1.136     brouard  9888:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9889:      printf("cptcovprod=%d ", cptcovprod);
                   9890:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9891:      scanf("%d ",i);*/
                   9892: 
                   9893: 
1.230     brouard  9894: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9895:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9896: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9897:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9898:    k =           1    2   3     4       5       6      7      8        9
                   9899:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9900:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9901:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9902:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9903:          Tmodelind[combination of covar]=k;
1.225     brouard  9904: */  
                   9905: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9906:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9907:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9908:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9909:   printf("Model=%s\n\
                   9910: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9911: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9912: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9913:   fprintf(ficlog,"Model=%s\n\
                   9914: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9915: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9916: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  9917:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9918:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9919:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9920:       Fixed[k]= 0;
                   9921:       Dummy[k]= 0;
1.225     brouard  9922:       ncoveff++;
1.232     brouard  9923:       ncovf++;
1.234     brouard  9924:       nsd++;
                   9925:       modell[k].maintype= FTYPE;
                   9926:       TvarsD[nsd]=Tvar[k];
                   9927:       TvarsDind[nsd]=k;
                   9928:       TvarF[ncovf]=Tvar[k];
                   9929:       TvarFind[ncovf]=k;
                   9930:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9931:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9932:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9933:       Fixed[k]= 0;
                   9934:       Dummy[k]= 0;
                   9935:       ncoveff++;
                   9936:       ncovf++;
                   9937:       modell[k].maintype= FTYPE;
                   9938:       TvarF[ncovf]=Tvar[k];
                   9939:       TvarFind[ncovf]=k;
1.230     brouard  9940:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9941:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9942:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9943:       Fixed[k]= 0;
                   9944:       Dummy[k]= 1;
1.230     brouard  9945:       nqfveff++;
1.234     brouard  9946:       modell[k].maintype= FTYPE;
                   9947:       modell[k].subtype= FQ;
                   9948:       nsq++;
                   9949:       TvarsQ[nsq]=Tvar[k];
                   9950:       TvarsQind[nsq]=k;
1.232     brouard  9951:       ncovf++;
1.234     brouard  9952:       TvarF[ncovf]=Tvar[k];
                   9953:       TvarFind[ncovf]=k;
1.231     brouard  9954:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9955:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9956:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9957:       Fixed[k]= 1;
                   9958:       Dummy[k]= 0;
1.225     brouard  9959:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9960:       modell[k].maintype= VTYPE;
                   9961:       modell[k].subtype= VD;
                   9962:       nsd++;
                   9963:       TvarsD[nsd]=Tvar[k];
                   9964:       TvarsDind[nsd]=k;
                   9965:       ncovv++; /* Only simple time varying variables */
                   9966:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9967:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9968:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9969:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9970:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9971:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9972:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9973:       Fixed[k]= 1;
                   9974:       Dummy[k]= 1;
                   9975:       nqtveff++;
                   9976:       modell[k].maintype= VTYPE;
                   9977:       modell[k].subtype= VQ;
                   9978:       ncovv++; /* Only simple time varying variables */
                   9979:       nsq++;
                   9980:       TvarsQ[nsq]=Tvar[k];
                   9981:       TvarsQind[nsq]=k;
                   9982:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9983:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9984:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9985:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9986:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   9987:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   9988:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  9989:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  9990:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  9991:       ncova++;
                   9992:       TvarA[ncova]=Tvar[k];
                   9993:       TvarAind[ncova]=k;
1.231     brouard  9994:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  9995:        Fixed[k]= 2;
                   9996:        Dummy[k]= 2;
                   9997:        modell[k].maintype= ATYPE;
                   9998:        modell[k].subtype= APFD;
                   9999:        /* ncoveff++; */
1.227     brouard  10000:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  10001:        Fixed[k]= 2;
                   10002:        Dummy[k]= 3;
                   10003:        modell[k].maintype= ATYPE;
                   10004:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   10005:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  10006:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  10007:        Fixed[k]= 3;
                   10008:        Dummy[k]= 2;
                   10009:        modell[k].maintype= ATYPE;
                   10010:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   10011:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  10012:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10013:        Fixed[k]= 3;
                   10014:        Dummy[k]= 3;
                   10015:        modell[k].maintype= ATYPE;
                   10016:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   10017:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  10018:       }
                   10019:     }else if (Typevar[k] == 2) {  /* product without age */
                   10020:       k1=Tposprod[k];
                   10021:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  10022:        if(Tvard[k1][2] <=ncovcol){
                   10023:          Fixed[k]= 1;
                   10024:          Dummy[k]= 0;
                   10025:          modell[k].maintype= FTYPE;
                   10026:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   10027:          ncovf++; /* Fixed variables without age */
                   10028:          TvarF[ncovf]=Tvar[k];
                   10029:          TvarFind[ncovf]=k;
                   10030:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10031:          Fixed[k]= 0;  /* or 2 ?*/
                   10032:          Dummy[k]= 1;
                   10033:          modell[k].maintype= FTYPE;
                   10034:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   10035:          ncovf++; /* Varying variables without age */
                   10036:          TvarF[ncovf]=Tvar[k];
                   10037:          TvarFind[ncovf]=k;
                   10038:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10039:          Fixed[k]= 1;
                   10040:          Dummy[k]= 0;
                   10041:          modell[k].maintype= VTYPE;
                   10042:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   10043:          ncovv++; /* Varying variables without age */
                   10044:          TvarV[ncovv]=Tvar[k];
                   10045:          TvarVind[ncovv]=k;
                   10046:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10047:          Fixed[k]= 1;
                   10048:          Dummy[k]= 1;
                   10049:          modell[k].maintype= VTYPE;
                   10050:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   10051:          ncovv++; /* Varying variables without age */
                   10052:          TvarV[ncovv]=Tvar[k];
                   10053:          TvarVind[ncovv]=k;
                   10054:        }
1.227     brouard  10055:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  10056:        if(Tvard[k1][2] <=ncovcol){
                   10057:          Fixed[k]= 0;  /* or 2 ?*/
                   10058:          Dummy[k]= 1;
                   10059:          modell[k].maintype= FTYPE;
                   10060:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   10061:          ncovf++; /* Fixed variables without age */
                   10062:          TvarF[ncovf]=Tvar[k];
                   10063:          TvarFind[ncovf]=k;
                   10064:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10065:          Fixed[k]= 1;
                   10066:          Dummy[k]= 1;
                   10067:          modell[k].maintype= VTYPE;
                   10068:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   10069:          ncovv++; /* Varying variables without age */
                   10070:          TvarV[ncovv]=Tvar[k];
                   10071:          TvarVind[ncovv]=k;
                   10072:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10073:          Fixed[k]= 1;
                   10074:          Dummy[k]= 1;
                   10075:          modell[k].maintype= VTYPE;
                   10076:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   10077:          ncovv++; /* Varying variables without age */
                   10078:          TvarV[ncovv]=Tvar[k];
                   10079:          TvarVind[ncovv]=k;
                   10080:          ncovv++; /* Varying variables without age */
                   10081:          TvarV[ncovv]=Tvar[k];
                   10082:          TvarVind[ncovv]=k;
                   10083:        }
1.227     brouard  10084:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  10085:        if(Tvard[k1][2] <=ncovcol){
                   10086:          Fixed[k]= 1;
                   10087:          Dummy[k]= 1;
                   10088:          modell[k].maintype= VTYPE;
                   10089:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   10090:          ncovv++; /* Varying variables without age */
                   10091:          TvarV[ncovv]=Tvar[k];
                   10092:          TvarVind[ncovv]=k;
                   10093:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10094:          Fixed[k]= 1;
                   10095:          Dummy[k]= 1;
                   10096:          modell[k].maintype= VTYPE;
                   10097:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   10098:          ncovv++; /* Varying variables without age */
                   10099:          TvarV[ncovv]=Tvar[k];
                   10100:          TvarVind[ncovv]=k;
                   10101:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10102:          Fixed[k]= 1;
                   10103:          Dummy[k]= 0;
                   10104:          modell[k].maintype= VTYPE;
                   10105:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   10106:          ncovv++; /* Varying variables without age */
                   10107:          TvarV[ncovv]=Tvar[k];
                   10108:          TvarVind[ncovv]=k;
                   10109:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10110:          Fixed[k]= 1;
                   10111:          Dummy[k]= 1;
                   10112:          modell[k].maintype= VTYPE;
                   10113:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   10114:          ncovv++; /* Varying variables without age */
                   10115:          TvarV[ncovv]=Tvar[k];
                   10116:          TvarVind[ncovv]=k;
                   10117:        }
1.227     brouard  10118:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10119:        if(Tvard[k1][2] <=ncovcol){
                   10120:          Fixed[k]= 1;
                   10121:          Dummy[k]= 1;
                   10122:          modell[k].maintype= VTYPE;
                   10123:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   10124:          ncovv++; /* Varying variables without age */
                   10125:          TvarV[ncovv]=Tvar[k];
                   10126:          TvarVind[ncovv]=k;
                   10127:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10128:          Fixed[k]= 1;
                   10129:          Dummy[k]= 1;
                   10130:          modell[k].maintype= VTYPE;
                   10131:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   10132:          ncovv++; /* Varying variables without age */
                   10133:          TvarV[ncovv]=Tvar[k];
                   10134:          TvarVind[ncovv]=k;
                   10135:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10136:          Fixed[k]= 1;
                   10137:          Dummy[k]= 1;
                   10138:          modell[k].maintype= VTYPE;
                   10139:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   10140:          ncovv++; /* Varying variables without age */
                   10141:          TvarV[ncovv]=Tvar[k];
                   10142:          TvarVind[ncovv]=k;
                   10143:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10144:          Fixed[k]= 1;
                   10145:          Dummy[k]= 1;
                   10146:          modell[k].maintype= VTYPE;
                   10147:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10148:          ncovv++; /* Varying variables without age */
                   10149:          TvarV[ncovv]=Tvar[k];
                   10150:          TvarVind[ncovv]=k;
                   10151:        }
1.227     brouard  10152:       }else{
1.240     brouard  10153:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10154:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10155:       } /*end k1*/
1.225     brouard  10156:     }else{
1.226     brouard  10157:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10158:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10159:     }
1.227     brouard  10160:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10161:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10162:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10163:   }
                   10164:   /* Searching for doublons in the model */
                   10165:   for(k1=1; k1<= cptcovt;k1++){
                   10166:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10167:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10168:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10169:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10170:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10171:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10172:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10173:            return(1);
                   10174:          }
                   10175:        }else if (Typevar[k1] ==2){
                   10176:          k3=Tposprod[k1];
                   10177:          k4=Tposprod[k2];
                   10178:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10179:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10180:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10181:            return(1);
                   10182:          }
                   10183:        }
1.227     brouard  10184:       }
                   10185:     }
1.225     brouard  10186:   }
                   10187:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10188:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10189:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10190:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10191:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10192:   /*endread:*/
1.225     brouard  10193:   printf("Exiting decodemodel: ");
                   10194:   return (1);
1.136     brouard  10195: }
                   10196: 
1.169     brouard  10197: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10198: {/* Check ages at death */
1.136     brouard  10199:   int i, m;
1.218     brouard  10200:   int firstone=0;
                   10201:   
1.136     brouard  10202:   for (i=1; i<=imx; i++) {
                   10203:     for(m=2; (m<= maxwav); m++) {
                   10204:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10205:        anint[m][i]=9999;
1.216     brouard  10206:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10207:          s[m][i]=-1;
1.136     brouard  10208:       }
                   10209:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10210:        *nberr = *nberr + 1;
1.218     brouard  10211:        if(firstone == 0){
                   10212:          firstone=1;
1.260     brouard  10213:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10214:        }
1.262     brouard  10215:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10216:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10217:       }
                   10218:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10219:        (*nberr)++;
1.259     brouard  10220:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10221:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10222:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10223:       }
                   10224:     }
                   10225:   }
                   10226: 
                   10227:   for (i=1; i<=imx; i++)  {
                   10228:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10229:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10230:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10231:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10232:          if(agedc[i]>0){
                   10233:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10234:              agev[m][i]=agedc[i];
1.214     brouard  10235:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10236:            }else {
1.136     brouard  10237:              if ((int)andc[i]!=9999){
                   10238:                nbwarn++;
                   10239:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10240:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10241:                agev[m][i]=-1;
                   10242:              }
                   10243:            }
1.169     brouard  10244:          } /* agedc > 0 */
1.214     brouard  10245:        } /* end if */
1.136     brouard  10246:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10247:                                 years but with the precision of a month */
                   10248:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10249:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10250:            agev[m][i]=1;
                   10251:          else if(agev[m][i] < *agemin){ 
                   10252:            *agemin=agev[m][i];
                   10253:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10254:          }
                   10255:          else if(agev[m][i] >*agemax){
                   10256:            *agemax=agev[m][i];
1.156     brouard  10257:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10258:          }
                   10259:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10260:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10261:        } /* en if 9*/
1.136     brouard  10262:        else { /* =9 */
1.214     brouard  10263:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10264:          agev[m][i]=1;
                   10265:          s[m][i]=-1;
                   10266:        }
                   10267:       }
1.214     brouard  10268:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10269:        agev[m][i]=1;
1.214     brouard  10270:       else{
                   10271:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10272:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10273:        agev[m][i]=0;
                   10274:       }
                   10275:     } /* End for lastpass */
                   10276:   }
1.136     brouard  10277:     
                   10278:   for (i=1; i<=imx; i++)  {
                   10279:     for(m=firstpass; (m<=lastpass); m++){
                   10280:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10281:        (*nberr)++;
1.136     brouard  10282:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10283:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10284:        return 1;
                   10285:       }
                   10286:     }
                   10287:   }
                   10288: 
                   10289:   /*for (i=1; i<=imx; i++){
                   10290:   for (m=firstpass; (m<lastpass); m++){
                   10291:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10292: }
                   10293: 
                   10294: }*/
                   10295: 
                   10296: 
1.139     brouard  10297:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10298:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10299: 
                   10300:   return (0);
1.164     brouard  10301:  /* endread:*/
1.136     brouard  10302:     printf("Exiting calandcheckages: ");
                   10303:     return (1);
                   10304: }
                   10305: 
1.172     brouard  10306: #if defined(_MSC_VER)
                   10307: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10308: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10309: //#include "stdafx.h"
                   10310: //#include <stdio.h>
                   10311: //#include <tchar.h>
                   10312: //#include <windows.h>
                   10313: //#include <iostream>
                   10314: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10315: 
                   10316: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10317: 
                   10318: BOOL IsWow64()
                   10319: {
                   10320:        BOOL bIsWow64 = FALSE;
                   10321: 
                   10322:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10323:        //  (HANDLE, PBOOL);
                   10324: 
                   10325:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10326: 
                   10327:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10328:        const char funcName[] = "IsWow64Process";
                   10329:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10330:                GetProcAddress(module, funcName);
                   10331: 
                   10332:        if (NULL != fnIsWow64Process)
                   10333:        {
                   10334:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10335:                        &bIsWow64))
                   10336:                        //throw std::exception("Unknown error");
                   10337:                        printf("Unknown error\n");
                   10338:        }
                   10339:        return bIsWow64 != FALSE;
                   10340: }
                   10341: #endif
1.177     brouard  10342: 
1.191     brouard  10343: void syscompilerinfo(int logged)
1.292     brouard  10344: {
                   10345: #include <stdint.h>
                   10346: 
                   10347:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10348:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10349:    /* /GS /W3 /Gy
                   10350:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10351:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10352:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10353:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10354:    */ 
                   10355:    /* 64 bits */
1.185     brouard  10356:    /*
                   10357:      /GS /W3 /Gy
                   10358:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10359:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10360:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10361:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10362:    /* Optimization are useless and O3 is slower than O2 */
                   10363:    /*
                   10364:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10365:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10366:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10367:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10368:    */
1.186     brouard  10369:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10370:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10371:       /PDB:"visual studio
                   10372:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10373:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10374:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10375:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10376:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10377:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10378:       uiAccess='false'"
                   10379:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10380:       /NOLOGO /TLBID:1
                   10381:    */
1.292     brouard  10382: 
                   10383: 
1.177     brouard  10384: #if defined __INTEL_COMPILER
1.178     brouard  10385: #if defined(__GNUC__)
                   10386:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10387: #endif
1.177     brouard  10388: #elif defined(__GNUC__) 
1.179     brouard  10389: #ifndef  __APPLE__
1.174     brouard  10390: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10391: #endif
1.177     brouard  10392:    struct utsname sysInfo;
1.178     brouard  10393:    int cross = CROSS;
                   10394:    if (cross){
                   10395:           printf("Cross-");
1.191     brouard  10396:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10397:    }
1.174     brouard  10398: #endif
                   10399: 
1.191     brouard  10400:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10401: #if defined(__clang__)
1.191     brouard  10402:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10403: #endif
                   10404: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10405:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10406: #endif
                   10407: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10408:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10409: #endif
                   10410: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10411:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10412: #endif
                   10413: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10414:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10415: #endif
                   10416: #if defined(_MSC_VER)
1.191     brouard  10417:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10418: #endif
                   10419: #if defined(__PGI)
1.191     brouard  10420:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10421: #endif
                   10422: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10423:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10424: #endif
1.191     brouard  10425:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10426:    
1.167     brouard  10427: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10428: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10429:     // Windows (x64 and x86)
1.191     brouard  10430:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10431: #elif __unix__ // all unices, not all compilers
                   10432:     // Unix
1.191     brouard  10433:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10434: #elif __linux__
                   10435:     // linux
1.191     brouard  10436:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10437: #elif __APPLE__
1.174     brouard  10438:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10439:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10440: #endif
                   10441: 
                   10442: /*  __MINGW32__          */
                   10443: /*  __CYGWIN__  */
                   10444: /* __MINGW64__  */
                   10445: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10446: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10447: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10448: /* _WIN64  // Defined for applications for Win64. */
                   10449: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10450: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10451: 
1.167     brouard  10452: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10453:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10454: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10455:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10456: #else
1.191     brouard  10457:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10458: #endif
                   10459: 
1.169     brouard  10460: #if defined(__GNUC__)
                   10461: # if defined(__GNUC_PATCHLEVEL__)
                   10462: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10463:                             + __GNUC_MINOR__ * 100 \
                   10464:                             + __GNUC_PATCHLEVEL__)
                   10465: # else
                   10466: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10467:                             + __GNUC_MINOR__ * 100)
                   10468: # endif
1.174     brouard  10469:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10470:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10471: 
                   10472:    if (uname(&sysInfo) != -1) {
                   10473:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10474:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10475:    }
                   10476:    else
                   10477:       perror("uname() error");
1.179     brouard  10478:    //#ifndef __INTEL_COMPILER 
                   10479: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10480:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10481:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10482: #endif
1.169     brouard  10483: #endif
1.172     brouard  10484: 
1.286     brouard  10485:    //   void main ()
1.172     brouard  10486:    //   {
1.169     brouard  10487: #if defined(_MSC_VER)
1.174     brouard  10488:    if (IsWow64()){
1.191     brouard  10489:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10490:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10491:    }
                   10492:    else{
1.191     brouard  10493:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10494:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10495:    }
1.172     brouard  10496:    //     printf("\nPress Enter to continue...");
                   10497:    //     getchar();
                   10498:    //   }
                   10499: 
1.169     brouard  10500: #endif
                   10501:    
1.167     brouard  10502: 
1.219     brouard  10503: }
1.136     brouard  10504: 
1.219     brouard  10505: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10506:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10507:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10508:   /* double ftolpl = 1.e-10; */
1.180     brouard  10509:   double age, agebase, agelim;
1.203     brouard  10510:   double tot;
1.180     brouard  10511: 
1.202     brouard  10512:   strcpy(filerespl,"PL_");
                   10513:   strcat(filerespl,fileresu);
                   10514:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10515:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10516:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10517:   }
1.288     brouard  10518:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10519:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10520:   pstamp(ficrespl);
1.288     brouard  10521:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10522:   fprintf(ficrespl,"#Age ");
                   10523:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10524:   fprintf(ficrespl,"\n");
1.180     brouard  10525:   
1.219     brouard  10526:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10527: 
1.219     brouard  10528:   agebase=ageminpar;
                   10529:   agelim=agemaxpar;
1.180     brouard  10530: 
1.227     brouard  10531:   /* i1=pow(2,ncoveff); */
1.234     brouard  10532:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10533:   if (cptcovn < 1){i1=1;}
1.180     brouard  10534: 
1.238     brouard  10535:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10536:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10537:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10538:        continue;
1.235     brouard  10539: 
1.238     brouard  10540:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10541:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10542:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10543:       /* k=k+1; */
                   10544:       /* to clean */
                   10545:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10546:       fprintf(ficrespl,"#******");
                   10547:       printf("#******");
                   10548:       fprintf(ficlog,"#******");
                   10549:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10550:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10551:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10552:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10553:       }
                   10554:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10555:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10556:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10557:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10558:       }
                   10559:       fprintf(ficrespl,"******\n");
                   10560:       printf("******\n");
                   10561:       fprintf(ficlog,"******\n");
                   10562:       if(invalidvarcomb[k]){
                   10563:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10564:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10565:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10566:        continue;
                   10567:       }
1.219     brouard  10568: 
1.238     brouard  10569:       fprintf(ficrespl,"#Age ");
                   10570:       for(j=1;j<=cptcoveff;j++) {
                   10571:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10572:       }
                   10573:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10574:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10575:     
1.238     brouard  10576:       for (age=agebase; age<=agelim; age++){
                   10577:        /* for (age=agebase; age<=agebase; age++){ */
                   10578:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10579:        fprintf(ficrespl,"%.0f ",age );
                   10580:        for(j=1;j<=cptcoveff;j++)
                   10581:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10582:        tot=0.;
                   10583:        for(i=1; i<=nlstate;i++){
                   10584:          tot +=  prlim[i][i];
                   10585:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10586:        }
                   10587:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10588:       } /* Age */
                   10589:       /* was end of cptcod */
                   10590:     } /* cptcov */
                   10591:   } /* nres */
1.219     brouard  10592:   return 0;
1.180     brouard  10593: }
                   10594: 
1.218     brouard  10595: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10596:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10597:        
                   10598:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10599:    * at any age between ageminpar and agemaxpar
                   10600:         */
1.235     brouard  10601:   int i, j, k, i1, nres=0 ;
1.217     brouard  10602:   /* double ftolpl = 1.e-10; */
                   10603:   double age, agebase, agelim;
                   10604:   double tot;
1.218     brouard  10605:   /* double ***mobaverage; */
                   10606:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10607: 
                   10608:   strcpy(fileresplb,"PLB_");
                   10609:   strcat(fileresplb,fileresu);
                   10610:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10611:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10612:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10613:   }
1.288     brouard  10614:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10615:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10616:   pstamp(ficresplb);
1.288     brouard  10617:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10618:   fprintf(ficresplb,"#Age ");
                   10619:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10620:   fprintf(ficresplb,"\n");
                   10621:   
1.218     brouard  10622:   
                   10623:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10624:   
                   10625:   agebase=ageminpar;
                   10626:   agelim=agemaxpar;
                   10627:   
                   10628:   
1.227     brouard  10629:   i1=pow(2,cptcoveff);
1.218     brouard  10630:   if (cptcovn < 1){i1=1;}
1.227     brouard  10631:   
1.238     brouard  10632:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10633:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10634:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10635:        continue;
                   10636:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10637:       fprintf(ficresplb,"#******");
                   10638:       printf("#******");
                   10639:       fprintf(ficlog,"#******");
                   10640:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10641:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10642:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10643:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10644:       }
                   10645:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10646:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10647:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10648:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10649:       }
                   10650:       fprintf(ficresplb,"******\n");
                   10651:       printf("******\n");
                   10652:       fprintf(ficlog,"******\n");
                   10653:       if(invalidvarcomb[k]){
                   10654:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10655:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10656:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10657:        continue;
                   10658:       }
1.218     brouard  10659:     
1.238     brouard  10660:       fprintf(ficresplb,"#Age ");
                   10661:       for(j=1;j<=cptcoveff;j++) {
                   10662:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10663:       }
                   10664:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10665:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10666:     
                   10667:     
1.238     brouard  10668:       for (age=agebase; age<=agelim; age++){
                   10669:        /* for (age=agebase; age<=agebase; age++){ */
                   10670:        if(mobilavproj > 0){
                   10671:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10672:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10673:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10674:        }else if (mobilavproj == 0){
                   10675:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10676:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10677:          exit(1);
                   10678:        }else{
                   10679:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10680:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10681:          /* printf("TOTOT\n"); */
                   10682:           /* exit(1); */
1.238     brouard  10683:        }
                   10684:        fprintf(ficresplb,"%.0f ",age );
                   10685:        for(j=1;j<=cptcoveff;j++)
                   10686:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10687:        tot=0.;
                   10688:        for(i=1; i<=nlstate;i++){
                   10689:          tot +=  bprlim[i][i];
                   10690:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10691:        }
                   10692:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10693:       } /* Age */
                   10694:       /* was end of cptcod */
1.255     brouard  10695:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10696:     } /* end of any combination */
                   10697:   } /* end of nres */  
1.218     brouard  10698:   /* hBijx(p, bage, fage); */
                   10699:   /* fclose(ficrespijb); */
                   10700:   
                   10701:   return 0;
1.217     brouard  10702: }
1.218     brouard  10703:  
1.180     brouard  10704: int hPijx(double *p, int bage, int fage){
                   10705:     /*------------- h Pij x at various ages ------------*/
                   10706: 
                   10707:   int stepsize;
                   10708:   int agelim;
                   10709:   int hstepm;
                   10710:   int nhstepm;
1.235     brouard  10711:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10712: 
                   10713:   double agedeb;
                   10714:   double ***p3mat;
                   10715: 
1.201     brouard  10716:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10717:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10718:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10719:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10720:     }
                   10721:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10722:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10723:   
                   10724:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10725:     /*if (stepm<=24) stepsize=2;*/
                   10726: 
                   10727:     agelim=AGESUP;
                   10728:     hstepm=stepsize*YEARM; /* Every year of age */
                   10729:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10730:                
1.180     brouard  10731:     /* hstepm=1;   aff par mois*/
                   10732:     pstamp(ficrespij);
                   10733:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10734:     i1= pow(2,cptcoveff);
1.218     brouard  10735:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10736:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10737:                /*      k=k+1;  */
1.235     brouard  10738:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10739:     for(k=1; k<=i1;k++){
1.253     brouard  10740:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10741:        continue;
1.183     brouard  10742:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10743:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10744:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10745:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10746:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10747:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10748:       }
1.183     brouard  10749:       fprintf(ficrespij,"******\n");
                   10750:       
                   10751:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10752:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10753:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10754:        
                   10755:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10756:        
1.183     brouard  10757:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10758:        oldm=oldms;savm=savms;
1.235     brouard  10759:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10760:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10761:        for(i=1; i<=nlstate;i++)
                   10762:          for(j=1; j<=nlstate+ndeath;j++)
                   10763:            fprintf(ficrespij," %1d-%1d",i,j);
                   10764:        fprintf(ficrespij,"\n");
                   10765:        for (h=0; h<=nhstepm; h++){
                   10766:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10767:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10768:          for(i=1; i<=nlstate;i++)
                   10769:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10770:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10771:          fprintf(ficrespij,"\n");
                   10772:        }
1.183     brouard  10773:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10774:        fprintf(ficrespij,"\n");
                   10775:       }
1.180     brouard  10776:       /*}*/
                   10777:     }
1.218     brouard  10778:     return 0;
1.180     brouard  10779: }
1.218     brouard  10780:  
                   10781:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10782:     /*------------- h Bij x at various ages ------------*/
                   10783: 
                   10784:   int stepsize;
1.218     brouard  10785:   /* int agelim; */
                   10786:        int ageminl;
1.217     brouard  10787:   int hstepm;
                   10788:   int nhstepm;
1.238     brouard  10789:   int h, i, i1, j, k, nres;
1.218     brouard  10790:        
1.217     brouard  10791:   double agedeb;
                   10792:   double ***p3mat;
1.218     brouard  10793:        
                   10794:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10795:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10796:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10797:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10798:   }
                   10799:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10800:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10801:   
                   10802:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10803:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10804:   
1.218     brouard  10805:   /* agelim=AGESUP; */
1.289     brouard  10806:   ageminl=AGEINF; /* was 30 */
1.218     brouard  10807:   hstepm=stepsize*YEARM; /* Every year of age */
                   10808:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10809:   
                   10810:   /* hstepm=1;   aff par mois*/
                   10811:   pstamp(ficrespijb);
1.255     brouard  10812:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10813:   i1= pow(2,cptcoveff);
1.218     brouard  10814:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10815:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10816:   /*   k=k+1;  */
1.238     brouard  10817:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10818:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10819:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10820:        continue;
                   10821:       fprintf(ficrespijb,"\n#****** ");
                   10822:       for(j=1;j<=cptcoveff;j++)
                   10823:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10824:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10825:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10826:       }
                   10827:       fprintf(ficrespijb,"******\n");
1.264     brouard  10828:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10829:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10830:        continue;
                   10831:       }
                   10832:       
                   10833:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10834:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10835:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
1.297     brouard  10836:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm+0.1)-1; /* Typically 20 years = 20*12/6=40 or 55*12/24=27.5-1.1=>27 */
                   10837:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 or 28*/
1.238     brouard  10838:        
                   10839:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10840:        
1.266     brouard  10841:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10842:        /* and memory limitations if stepm is small */
                   10843: 
1.238     brouard  10844:        /* oldm=oldms;savm=savms; */
                   10845:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10846:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10847:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10848:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10849:        for(i=1; i<=nlstate;i++)
                   10850:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10851:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10852:        fprintf(ficrespijb,"\n");
1.238     brouard  10853:        for (h=0; h<=nhstepm; h++){
                   10854:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10855:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10856:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10857:          for(i=1; i<=nlstate;i++)
                   10858:            for(j=1; j<=nlstate+ndeath;j++)
                   10859:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10860:          fprintf(ficrespijb,"\n");
                   10861:        }
                   10862:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10863:        fprintf(ficrespijb,"\n");
                   10864:       } /* end age deb */
                   10865:     } /* end combination */
                   10866:   } /* end nres */
1.218     brouard  10867:   return 0;
                   10868:  } /*  hBijx */
1.217     brouard  10869: 
1.180     brouard  10870: 
1.136     brouard  10871: /***********************************************/
                   10872: /**************** Main Program *****************/
                   10873: /***********************************************/
                   10874: 
                   10875: int main(int argc, char *argv[])
                   10876: {
                   10877: #ifdef GSL
                   10878:   const gsl_multimin_fminimizer_type *T;
                   10879:   size_t iteri = 0, it;
                   10880:   int rval = GSL_CONTINUE;
                   10881:   int status = GSL_SUCCESS;
                   10882:   double ssval;
                   10883: #endif
                   10884:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  10885:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   10886:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  10887:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10888:   int jj, ll, li, lj, lk;
1.136     brouard  10889:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10890:   int num_filled;
1.136     brouard  10891:   int itimes;
                   10892:   int NDIM=2;
                   10893:   int vpopbased=0;
1.235     brouard  10894:   int nres=0;
1.258     brouard  10895:   int endishere=0;
1.277     brouard  10896:   int noffset=0;
1.274     brouard  10897:   int ncurrv=0; /* Temporary variable */
                   10898:   
1.164     brouard  10899:   char ca[32], cb[32];
1.136     brouard  10900:   /*  FILE *fichtm; *//* Html File */
                   10901:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10902:   struct stat info;
1.191     brouard  10903:   double agedeb=0.;
1.194     brouard  10904: 
                   10905:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10906:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10907: 
1.165     brouard  10908:   double fret;
1.191     brouard  10909:   double dum=0.; /* Dummy variable */
1.136     brouard  10910:   double ***p3mat;
1.218     brouard  10911:   /* double ***mobaverage; */
1.164     brouard  10912: 
                   10913:   char line[MAXLINE];
1.197     brouard  10914:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10915: 
1.234     brouard  10916:   char  modeltemp[MAXLINE];
1.230     brouard  10917:   char resultline[MAXLINE];
                   10918:   
1.136     brouard  10919:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10920:   char *tok, *val; /* pathtot */
1.290     brouard  10921:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  10922:   int c,  h , cpt, c2;
1.191     brouard  10923:   int jl=0;
                   10924:   int i1, j1, jk, stepsize=0;
1.194     brouard  10925:   int count=0;
                   10926: 
1.164     brouard  10927:   int *tab; 
1.136     brouard  10928:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.296     brouard  10929:   /* double anprojd, mprojd, jprojd; /\* For eventual projections *\/ */
                   10930:   /* double anprojf, mprojf, jprojf; */
                   10931:   /* double jintmean,mintmean,aintmean;   */
                   10932:   int prvforecast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   10933:   int prvbackcast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   10934:   double yrfproj= 10.0; /* Number of years of forward projections */
                   10935:   double yrbproj= 10.0; /* Number of years of backward projections */
                   10936:   int prevbcast=0; /* defined as global for mlikeli and mle, replacing backcast */
1.136     brouard  10937:   int mobilav=0,popforecast=0;
1.191     brouard  10938:   int hstepm=0, nhstepm=0;
1.136     brouard  10939:   int agemortsup;
                   10940:   float  sumlpop=0.;
                   10941:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10942:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10943: 
1.191     brouard  10944:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10945:   double ftolpl=FTOL;
                   10946:   double **prlim;
1.217     brouard  10947:   double **bprlim;
1.136     brouard  10948:   double ***param; /* Matrix of parameters */
1.251     brouard  10949:   double ***paramstart; /* Matrix of starting parameter values */
                   10950:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10951:   double **matcov; /* Matrix of covariance */
1.203     brouard  10952:   double **hess; /* Hessian matrix */
1.136     brouard  10953:   double ***delti3; /* Scale */
                   10954:   double *delti; /* Scale */
                   10955:   double ***eij, ***vareij;
                   10956:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10957: 
1.136     brouard  10958:   double *epj, vepp;
1.164     brouard  10959: 
1.273     brouard  10960:   double dateprev1, dateprev2;
1.296     brouard  10961:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0, dateprojd=0, dateprojf=0;
                   10962:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0, datebackd=0, datebackf=0;
                   10963: 
1.217     brouard  10964: 
1.136     brouard  10965:   double **ximort;
1.145     brouard  10966:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10967:   int *dcwave;
                   10968: 
1.164     brouard  10969:   char z[1]="c";
1.136     brouard  10970: 
                   10971:   /*char  *strt;*/
                   10972:   char strtend[80];
1.126     brouard  10973: 
1.164     brouard  10974: 
1.126     brouard  10975: /*   setlocale (LC_ALL, ""); */
                   10976: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10977: /*   textdomain (PACKAGE); */
                   10978: /*   setlocale (LC_CTYPE, ""); */
                   10979: /*   setlocale (LC_MESSAGES, ""); */
                   10980: 
                   10981:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10982:   rstart_time = time(NULL);  
                   10983:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10984:   start_time = *localtime(&rstart_time);
1.126     brouard  10985:   curr_time=start_time;
1.157     brouard  10986:   /*tml = *localtime(&start_time.tm_sec);*/
                   10987:   /* strcpy(strstart,asctime(&tml)); */
                   10988:   strcpy(strstart,asctime(&start_time));
1.126     brouard  10989: 
                   10990: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  10991: /*  tp.tm_sec = tp.tm_sec +86400; */
                   10992: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  10993: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   10994: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   10995: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  10996: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  10997: /*   strt=asctime(&tmg); */
                   10998: /*   printf("Time(after) =%s",strstart);  */
                   10999: /*  (void) time (&time_value);
                   11000: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   11001: *  tm = *localtime(&time_value);
                   11002: *  strstart=asctime(&tm);
                   11003: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   11004: */
                   11005: 
                   11006:   nberr=0; /* Number of errors and warnings */
                   11007:   nbwarn=0;
1.184     brouard  11008: #ifdef WIN32
                   11009:   _getcwd(pathcd, size);
                   11010: #else
1.126     brouard  11011:   getcwd(pathcd, size);
1.184     brouard  11012: #endif
1.191     brouard  11013:   syscompilerinfo(0);
1.196     brouard  11014:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  11015:   if(argc <=1){
                   11016:     printf("\nEnter the parameter file name: ");
1.205     brouard  11017:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   11018:       printf("ERROR Empty parameter file name\n");
                   11019:       goto end;
                   11020:     }
1.126     brouard  11021:     i=strlen(pathr);
                   11022:     if(pathr[i-1]=='\n')
                   11023:       pathr[i-1]='\0';
1.156     brouard  11024:     i=strlen(pathr);
1.205     brouard  11025:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  11026:       pathr[i-1]='\0';
1.205     brouard  11027:     }
                   11028:     i=strlen(pathr);
                   11029:     if( i==0 ){
                   11030:       printf("ERROR Empty parameter file name\n");
                   11031:       goto end;
                   11032:     }
                   11033:     for (tok = pathr; tok != NULL; ){
1.126     brouard  11034:       printf("Pathr |%s|\n",pathr);
                   11035:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   11036:       printf("val= |%s| pathr=%s\n",val,pathr);
                   11037:       strcpy (pathtot, val);
                   11038:       if(pathr[0] == '\0') break; /* Dirty */
                   11039:     }
                   11040:   }
1.281     brouard  11041:   else if (argc<=2){
                   11042:     strcpy(pathtot,argv[1]);
                   11043:   }
1.126     brouard  11044:   else{
                   11045:     strcpy(pathtot,argv[1]);
1.281     brouard  11046:     strcpy(z,argv[2]);
                   11047:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  11048:   }
                   11049:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   11050:   /*cygwin_split_path(pathtot,path,optionfile);
                   11051:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   11052:   /* cutv(path,optionfile,pathtot,'\\');*/
                   11053: 
                   11054:   /* Split argv[0], imach program to get pathimach */
                   11055:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   11056:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11057:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11058:  /*   strcpy(pathimach,argv[0]); */
                   11059:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   11060:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   11061:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  11062: #ifdef WIN32
                   11063:   _chdir(path); /* Can be a relative path */
                   11064:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   11065: #else
1.126     brouard  11066:   chdir(path); /* Can be a relative path */
1.184     brouard  11067:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   11068: #endif
                   11069:   printf("Current directory %s!\n",pathcd);
1.126     brouard  11070:   strcpy(command,"mkdir ");
                   11071:   strcat(command,optionfilefiname);
                   11072:   if((outcmd=system(command)) != 0){
1.169     brouard  11073:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  11074:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   11075:     /* fclose(ficlog); */
                   11076: /*     exit(1); */
                   11077:   }
                   11078: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   11079: /*     perror("mkdir"); */
                   11080: /*   } */
                   11081: 
                   11082:   /*-------- arguments in the command line --------*/
                   11083: 
1.186     brouard  11084:   /* Main Log file */
1.126     brouard  11085:   strcat(filelog, optionfilefiname);
                   11086:   strcat(filelog,".log");    /* */
                   11087:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   11088:     printf("Problem with logfile %s\n",filelog);
                   11089:     goto end;
                   11090:   }
                   11091:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  11092:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  11093:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   11094:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   11095:  path=%s \n\
                   11096:  optionfile=%s\n\
                   11097:  optionfilext=%s\n\
1.156     brouard  11098:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  11099: 
1.197     brouard  11100:   syscompilerinfo(1);
1.167     brouard  11101: 
1.126     brouard  11102:   printf("Local time (at start):%s",strstart);
                   11103:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   11104:   fflush(ficlog);
                   11105: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  11106: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  11107: 
                   11108:   /* */
                   11109:   strcpy(fileres,"r");
                   11110:   strcat(fileres, optionfilefiname);
1.201     brouard  11111:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  11112:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  11113:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  11114: 
1.186     brouard  11115:   /* Main ---------arguments file --------*/
1.126     brouard  11116: 
                   11117:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  11118:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   11119:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  11120:     fflush(ficlog);
1.149     brouard  11121:     /* goto end; */
                   11122:     exit(70); 
1.126     brouard  11123:   }
                   11124: 
                   11125:   strcpy(filereso,"o");
1.201     brouard  11126:   strcat(filereso,fileresu);
1.126     brouard  11127:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   11128:     printf("Problem with Output resultfile: %s\n", filereso);
                   11129:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   11130:     fflush(ficlog);
                   11131:     goto end;
                   11132:   }
1.278     brouard  11133:       /*-------- Rewriting parameter file ----------*/
                   11134:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   11135:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   11136:   strcat(rfileres,".");    /* */
                   11137:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11138:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   11139:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11140:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   11141:     fflush(ficlog);
                   11142:     goto end;
                   11143:   }
                   11144:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  11145: 
1.278     brouard  11146:                                      
1.126     brouard  11147:   /* Reads comments: lines beginning with '#' */
                   11148:   numlinepar=0;
1.277     brouard  11149:   /* Is it a BOM UTF-8 Windows file? */
                   11150:   /* First parameter line */
1.197     brouard  11151:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11152:     noffset=0;
                   11153:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11154:     {
                   11155:       noffset=noffset+3;
                   11156:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11157:     }
1.302     brouard  11158: /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   11159:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
1.277     brouard  11160:     {
                   11161:       noffset=noffset+2;
                   11162:       printf("# File is an UTF16BE BOM file\n");
                   11163:     }
                   11164:     else if( line[0] == 0 && line[1] == 0)
                   11165:     {
                   11166:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11167:        noffset=noffset+4;
                   11168:        printf("# File is an UTF16BE BOM file\n");
                   11169:       }
                   11170:     } else{
                   11171:       ;/*printf(" Not a BOM file\n");*/
                   11172:     }
                   11173:   
1.197     brouard  11174:     /* If line starts with a # it is a comment */
1.277     brouard  11175:     if (line[noffset] == '#') {
1.197     brouard  11176:       numlinepar++;
                   11177:       fputs(line,stdout);
                   11178:       fputs(line,ficparo);
1.278     brouard  11179:       fputs(line,ficres);
1.197     brouard  11180:       fputs(line,ficlog);
                   11181:       continue;
                   11182:     }else
                   11183:       break;
                   11184:   }
                   11185:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11186:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11187:     if (num_filled != 5) {
                   11188:       printf("Should be 5 parameters\n");
1.283     brouard  11189:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11190:     }
1.126     brouard  11191:     numlinepar++;
1.197     brouard  11192:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11193:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11194:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11195:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11196:   }
                   11197:   /* Second parameter line */
                   11198:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11199:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11200:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11201:     if (line[0] == '#') {
                   11202:       numlinepar++;
1.283     brouard  11203:       printf("%s",line);
                   11204:       fprintf(ficres,"%s",line);
                   11205:       fprintf(ficparo,"%s",line);
                   11206:       fprintf(ficlog,"%s",line);
1.197     brouard  11207:       continue;
                   11208:     }else
                   11209:       break;
                   11210:   }
1.223     brouard  11211:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11212:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11213:     if (num_filled != 11) {
                   11214:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11215:       printf("but line=%s\n",line);
1.283     brouard  11216:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11217:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11218:     }
1.286     brouard  11219:     if( lastpass > maxwav){
                   11220:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11221:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11222:       fflush(ficlog);
                   11223:       goto end;
                   11224:     }
                   11225:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11226:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11227:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11228:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11229:   }
1.203     brouard  11230:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11231:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11232:   /* Third parameter line */
                   11233:   while(fgets(line, MAXLINE, ficpar)) {
                   11234:     /* If line starts with a # it is a comment */
                   11235:     if (line[0] == '#') {
                   11236:       numlinepar++;
1.283     brouard  11237:       printf("%s",line);
                   11238:       fprintf(ficres,"%s",line);
                   11239:       fprintf(ficparo,"%s",line);
                   11240:       fprintf(ficlog,"%s",line);
1.197     brouard  11241:       continue;
                   11242:     }else
                   11243:       break;
                   11244:   }
1.201     brouard  11245:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11246:     if (num_filled != 1){
1.302     brouard  11247:       printf("ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
                   11248:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
1.197     brouard  11249:       model[0]='\0';
                   11250:       goto end;
                   11251:     }
                   11252:     else{
                   11253:       if (model[0]=='+'){
                   11254:        for(i=1; i<=strlen(model);i++)
                   11255:          modeltemp[i-1]=model[i];
1.201     brouard  11256:        strcpy(model,modeltemp); 
1.197     brouard  11257:       }
                   11258:     }
1.199     brouard  11259:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11260:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11261:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11262:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11263:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11264:   }
                   11265:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11266:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11267:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11268:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11269:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11270:   fflush(ficlog);
1.190     brouard  11271:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11272:   if(model[0]=='#'){
1.279     brouard  11273:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11274:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11275:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11276:     if(mle != -1){
1.279     brouard  11277:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11278:       exit(1);
                   11279:     }
                   11280:   }
1.126     brouard  11281:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11282:     ungetc(c,ficpar);
                   11283:     fgets(line, MAXLINE, ficpar);
                   11284:     numlinepar++;
1.195     brouard  11285:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11286:       z[0]=line[1];
                   11287:     }
                   11288:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11289:     fputs(line, stdout);
                   11290:     //puts(line);
1.126     brouard  11291:     fputs(line,ficparo);
                   11292:     fputs(line,ficlog);
                   11293:   }
                   11294:   ungetc(c,ficpar);
                   11295: 
                   11296:    
1.290     brouard  11297:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11298:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11299:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11300:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11301:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11302:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11303:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11304:   */
                   11305:   if (strlen(model)>1) 
1.187     brouard  11306:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11307:   else
1.187     brouard  11308:     ncovmodel=2; /* Constant and age */
1.133     brouard  11309:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11310:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11311:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11312:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11313:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11314:     fflush(stdout);
                   11315:     fclose (ficlog);
                   11316:     goto end;
                   11317:   }
1.126     brouard  11318:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11319:   delti=delti3[1][1];
                   11320:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11321:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11322: /* We could also provide initial parameters values giving by simple logistic regression 
                   11323:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11324:       /* for(i=1;i<nlstate;i++){ */
                   11325:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11326:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11327:       /* } */
1.126     brouard  11328:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11329:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11330:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11331:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11332:     fclose (ficparo);
                   11333:     fclose (ficlog);
                   11334:     goto end;
                   11335:     exit(0);
1.220     brouard  11336:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11337:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11338:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11339:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11340:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11341:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11342:     hess=matrix(1,npar,1,npar);
1.220     brouard  11343:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11344:     /* Read guessed parameters */
1.126     brouard  11345:     /* Reads comments: lines beginning with '#' */
                   11346:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11347:       ungetc(c,ficpar);
                   11348:       fgets(line, MAXLINE, ficpar);
                   11349:       numlinepar++;
1.141     brouard  11350:       fputs(line,stdout);
1.126     brouard  11351:       fputs(line,ficparo);
                   11352:       fputs(line,ficlog);
                   11353:     }
                   11354:     ungetc(c,ficpar);
                   11355:     
                   11356:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11357:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11358:     for(i=1; i <=nlstate; i++){
1.234     brouard  11359:       j=0;
1.126     brouard  11360:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11361:        if(jj==i) continue;
                   11362:        j++;
1.292     brouard  11363:        while((c=getc(ficpar))=='#' && c!= EOF){
                   11364:          ungetc(c,ficpar);
                   11365:          fgets(line, MAXLINE, ficpar);
                   11366:          numlinepar++;
                   11367:          fputs(line,stdout);
                   11368:          fputs(line,ficparo);
                   11369:          fputs(line,ficlog);
                   11370:        }
                   11371:        ungetc(c,ficpar);
1.234     brouard  11372:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11373:        if ((i1 != i) || (j1 != jj)){
                   11374:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11375: It might be a problem of design; if ncovcol and the model are correct\n \
                   11376: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11377:          exit(1);
                   11378:        }
                   11379:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11380:        if(mle==1)
                   11381:          printf("%1d%1d",i,jj);
                   11382:        fprintf(ficlog,"%1d%1d",i,jj);
                   11383:        for(k=1; k<=ncovmodel;k++){
                   11384:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11385:          if(mle==1){
                   11386:            printf(" %lf",param[i][j][k]);
                   11387:            fprintf(ficlog," %lf",param[i][j][k]);
                   11388:          }
                   11389:          else
                   11390:            fprintf(ficlog," %lf",param[i][j][k]);
                   11391:          fprintf(ficparo," %lf",param[i][j][k]);
                   11392:        }
                   11393:        fscanf(ficpar,"\n");
                   11394:        numlinepar++;
                   11395:        if(mle==1)
                   11396:          printf("\n");
                   11397:        fprintf(ficlog,"\n");
                   11398:        fprintf(ficparo,"\n");
1.126     brouard  11399:       }
                   11400:     }  
                   11401:     fflush(ficlog);
1.234     brouard  11402:     
1.251     brouard  11403:     /* Reads parameters values */
1.126     brouard  11404:     p=param[1][1];
1.251     brouard  11405:     pstart=paramstart[1][1];
1.126     brouard  11406:     
                   11407:     /* Reads comments: lines beginning with '#' */
                   11408:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11409:       ungetc(c,ficpar);
                   11410:       fgets(line, MAXLINE, ficpar);
                   11411:       numlinepar++;
1.141     brouard  11412:       fputs(line,stdout);
1.126     brouard  11413:       fputs(line,ficparo);
                   11414:       fputs(line,ficlog);
                   11415:     }
                   11416:     ungetc(c,ficpar);
                   11417: 
                   11418:     for(i=1; i <=nlstate; i++){
                   11419:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11420:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11421:        if ( (i1-i) * (j1-j) != 0){
                   11422:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11423:          exit(1);
                   11424:        }
                   11425:        printf("%1d%1d",i,j);
                   11426:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11427:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11428:        for(k=1; k<=ncovmodel;k++){
                   11429:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11430:          printf(" %le",delti3[i][j][k]);
                   11431:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11432:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11433:        }
                   11434:        fscanf(ficpar,"\n");
                   11435:        numlinepar++;
                   11436:        printf("\n");
                   11437:        fprintf(ficparo,"\n");
                   11438:        fprintf(ficlog,"\n");
1.126     brouard  11439:       }
                   11440:     }
                   11441:     fflush(ficlog);
1.234     brouard  11442:     
1.145     brouard  11443:     /* Reads covariance matrix */
1.126     brouard  11444:     delti=delti3[1][1];
1.220     brouard  11445:                
                   11446:                
1.126     brouard  11447:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11448:                
1.126     brouard  11449:     /* Reads comments: lines beginning with '#' */
                   11450:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11451:       ungetc(c,ficpar);
                   11452:       fgets(line, MAXLINE, ficpar);
                   11453:       numlinepar++;
1.141     brouard  11454:       fputs(line,stdout);
1.126     brouard  11455:       fputs(line,ficparo);
                   11456:       fputs(line,ficlog);
                   11457:     }
                   11458:     ungetc(c,ficpar);
1.220     brouard  11459:                
1.126     brouard  11460:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11461:     hess=matrix(1,npar,1,npar);
1.131     brouard  11462:     for(i=1; i <=npar; i++)
                   11463:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11464:                
1.194     brouard  11465:     /* Scans npar lines */
1.126     brouard  11466:     for(i=1; i <=npar; i++){
1.226     brouard  11467:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11468:       if(count != 3){
1.226     brouard  11469:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11470: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11471: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11472:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11473: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11474: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11475:        exit(1);
1.220     brouard  11476:       }else{
1.226     brouard  11477:        if(mle==1)
                   11478:          printf("%1d%1d%d",i1,j1,jk);
                   11479:       }
                   11480:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11481:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11482:       for(j=1; j <=i; j++){
1.226     brouard  11483:        fscanf(ficpar," %le",&matcov[i][j]);
                   11484:        if(mle==1){
                   11485:          printf(" %.5le",matcov[i][j]);
                   11486:        }
                   11487:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11488:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11489:       }
                   11490:       fscanf(ficpar,"\n");
                   11491:       numlinepar++;
                   11492:       if(mle==1)
1.220     brouard  11493:                                printf("\n");
1.126     brouard  11494:       fprintf(ficlog,"\n");
                   11495:       fprintf(ficparo,"\n");
                   11496:     }
1.194     brouard  11497:     /* End of read covariance matrix npar lines */
1.126     brouard  11498:     for(i=1; i <=npar; i++)
                   11499:       for(j=i+1;j<=npar;j++)
1.226     brouard  11500:        matcov[i][j]=matcov[j][i];
1.126     brouard  11501:     
                   11502:     if(mle==1)
                   11503:       printf("\n");
                   11504:     fprintf(ficlog,"\n");
                   11505:     
                   11506:     fflush(ficlog);
                   11507:     
                   11508:   }    /* End of mle != -3 */
1.218     brouard  11509:   
1.186     brouard  11510:   /*  Main data
                   11511:    */
1.290     brouard  11512:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11513:   /* num=lvector(1,n); */
                   11514:   /* moisnais=vector(1,n); */
                   11515:   /* annais=vector(1,n); */
                   11516:   /* moisdc=vector(1,n); */
                   11517:   /* andc=vector(1,n); */
                   11518:   /* weight=vector(1,n); */
                   11519:   /* agedc=vector(1,n); */
                   11520:   /* cod=ivector(1,n); */
                   11521:   /* for(i=1;i<=n;i++){ */
                   11522:   num=lvector(firstobs,lastobs);
                   11523:   moisnais=vector(firstobs,lastobs);
                   11524:   annais=vector(firstobs,lastobs);
                   11525:   moisdc=vector(firstobs,lastobs);
                   11526:   andc=vector(firstobs,lastobs);
                   11527:   weight=vector(firstobs,lastobs);
                   11528:   agedc=vector(firstobs,lastobs);
                   11529:   cod=ivector(firstobs,lastobs);
                   11530:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11531:     num[i]=0;
                   11532:     moisnais[i]=0;
                   11533:     annais[i]=0;
                   11534:     moisdc[i]=0;
                   11535:     andc[i]=0;
                   11536:     agedc[i]=0;
                   11537:     cod[i]=0;
                   11538:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11539:   }
1.290     brouard  11540:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11541:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11542:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11543:   tab=ivector(1,NCOVMAX);
1.144     brouard  11544:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11545:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11546: 
1.136     brouard  11547:   /* Reads data from file datafile */
                   11548:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11549:     goto end;
                   11550: 
                   11551:   /* Calculation of the number of parameters from char model */
1.234     brouard  11552:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11553:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11554:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11555:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11556:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11557:   */
                   11558:   
                   11559:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11560:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11561:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11562:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11563:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11564:   TvarF=ivector(1,NCOVMAX); /*  */
                   11565:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11566:   TvarV=ivector(1,NCOVMAX); /*  */
                   11567:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11568:   TvarA=ivector(1,NCOVMAX); /*  */
                   11569:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11570:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11571:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11572:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11573:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11574:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11575:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11576:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11577:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11578: 
1.230     brouard  11579:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11580:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11581:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11582:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11583:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11584:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11585:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11586:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11587:   */
                   11588:   /* For model-covariate k tells which data-covariate to use but
                   11589:     because this model-covariate is a construction we invent a new column
                   11590:     ncovcol + k1
                   11591:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11592:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11593:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11594:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11595:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11596:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11597:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11598:   */
1.145     brouard  11599:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11600:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11601:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11602:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11603:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11604:                         4 covariates (3 plus signs)
                   11605:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11606:                      */  
1.230     brouard  11607:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11608:                                * individual dummy, fixed or varying:
                   11609:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11610:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11611:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11612:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11613:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11614:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11615:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11616:                                * individual quantitative, fixed or varying:
                   11617:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11618:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11619:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11620: /* Main decodemodel */
                   11621: 
1.187     brouard  11622: 
1.223     brouard  11623:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11624:     goto end;
                   11625: 
1.137     brouard  11626:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11627:     nbwarn++;
                   11628:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11629:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11630:   }
1.136     brouard  11631:     /*  if(mle==1){*/
1.137     brouard  11632:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11633:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11634:   }
                   11635: 
                   11636:     /*-calculation of age at interview from date of interview and age at death -*/
                   11637:   agev=matrix(1,maxwav,1,imx);
                   11638: 
                   11639:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11640:     goto end;
                   11641: 
1.126     brouard  11642: 
1.136     brouard  11643:   agegomp=(int)agemin;
1.290     brouard  11644:   free_vector(moisnais,firstobs,lastobs);
                   11645:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11646:   /* free_matrix(mint,1,maxwav,1,n);
                   11647:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11648:   /* free_vector(moisdc,1,n); */
                   11649:   /* free_vector(andc,1,n); */
1.145     brouard  11650:   /* */
                   11651:   
1.126     brouard  11652:   wav=ivector(1,imx);
1.214     brouard  11653:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11654:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11655:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11656:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11657:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11658:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11659:    
                   11660:   /* Concatenates waves */
1.214     brouard  11661:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11662:      Death is a valid wave (if date is known).
                   11663:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11664:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11665:      and mw[mi+1][i]. dh depends on stepm.
                   11666:   */
                   11667: 
1.126     brouard  11668:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11669:   /* Concatenates waves */
1.145     brouard  11670:  
1.290     brouard  11671:   free_vector(moisdc,firstobs,lastobs);
                   11672:   free_vector(andc,firstobs,lastobs);
1.215     brouard  11673: 
1.126     brouard  11674:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11675:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11676:   ncodemax[1]=1;
1.145     brouard  11677:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11678:   cptcoveff=0;
1.220     brouard  11679:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11680:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11681:   }
                   11682:   
                   11683:   ncovcombmax=pow(2,cptcoveff);
                   11684:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11685:   for(i=1;i<ncovcombmax;i++)
                   11686:     invalidvarcomb[i]=0;
                   11687:   
1.211     brouard  11688:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11689:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11690:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11691:   
1.200     brouard  11692:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11693:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11694:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11695:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11696:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11697:    * (currently 0 or 1) in the data.
                   11698:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11699:    * corresponding modality (h,j).
                   11700:    */
                   11701: 
1.145     brouard  11702:   h=0;
                   11703:   /*if (cptcovn > 0) */
1.126     brouard  11704:   m=pow(2,cptcoveff);
                   11705:  
1.144     brouard  11706:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11707:           * For k=4 covariates, h goes from 1 to m=2**k
                   11708:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11709:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11710:           *     h\k   1     2     3     4
1.143     brouard  11711:           *______________________________  
                   11712:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11713:           *     2     2     1     1     1
                   11714:           *     3 i=2 1     2     1     1
                   11715:           *     4     2     2     1     1
                   11716:           *     5 i=3 1 i=2 1     2     1
                   11717:           *     6     2     1     2     1
                   11718:           *     7 i=4 1     2     2     1
                   11719:           *     8     2     2     2     1
1.197     brouard  11720:           *     9 i=5 1 i=3 1 i=2 1     2
                   11721:           *    10     2     1     1     2
                   11722:           *    11 i=6 1     2     1     2
                   11723:           *    12     2     2     1     2
                   11724:           *    13 i=7 1 i=4 1     2     2    
                   11725:           *    14     2     1     2     2
                   11726:           *    15 i=8 1     2     2     2
                   11727:           *    16     2     2     2     2
1.143     brouard  11728:           */
1.212     brouard  11729:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11730:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11731:      * and the value of each covariate?
                   11732:      * V1=1, V2=1, V3=2, V4=1 ?
                   11733:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11734:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11735:      * In order to get the real value in the data, we use nbcode
                   11736:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11737:      * We are keeping this crazy system in order to be able (in the future?) 
                   11738:      * to have more than 2 values (0 or 1) for a covariate.
                   11739:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11740:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11741:      *              bbbbbbbb
                   11742:      *              76543210     
                   11743:      *   h-1        00000101 (6-1=5)
1.219     brouard  11744:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11745:      *           &
                   11746:      *     1        00000001 (1)
1.219     brouard  11747:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11748:      *          +1= 00000001 =1 
1.211     brouard  11749:      *
                   11750:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11751:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11752:      *    >>k'            11
                   11753:      *          &   00000001
                   11754:      *            = 00000001
                   11755:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11756:      * Reverse h=6 and m=16?
                   11757:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11758:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11759:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11760:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11761:      * V3=decodtabm(14,3,2**4)=2
                   11762:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11763:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11764:      *          &1 000000001
                   11765:      *           = 000000001
                   11766:      *         +1= 000000010 =2
                   11767:      *                  2211
                   11768:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11769:      *                  V3=2
1.220     brouard  11770:                 * codtabm and decodtabm are identical
1.211     brouard  11771:      */
                   11772: 
1.145     brouard  11773: 
                   11774:  free_ivector(Ndum,-1,NCOVMAX);
                   11775: 
                   11776: 
1.126     brouard  11777:     
1.186     brouard  11778:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11779:   strcpy(optionfilegnuplot,optionfilefiname);
                   11780:   if(mle==-3)
1.201     brouard  11781:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11782:   strcat(optionfilegnuplot,".gp");
                   11783: 
                   11784:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11785:     printf("Problem with file %s",optionfilegnuplot);
                   11786:   }
                   11787:   else{
1.204     brouard  11788:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11789:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11790:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11791:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11792:   }
                   11793:   /*  fclose(ficgp);*/
1.186     brouard  11794: 
                   11795: 
                   11796:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11797: 
                   11798:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11799:   if(mle==-3)
1.201     brouard  11800:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11801:   strcat(optionfilehtm,".htm");
                   11802:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11803:     printf("Problem with %s \n",optionfilehtm);
                   11804:     exit(0);
1.126     brouard  11805:   }
                   11806: 
                   11807:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11808:   strcat(optionfilehtmcov,"-cov.htm");
                   11809:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11810:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11811:   }
                   11812:   else{
                   11813:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11814: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11815: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11816:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11817:   }
                   11818: 
1.213     brouard  11819:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11820: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11821: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11822: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11823: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11824: \n\
                   11825: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11826:  <ul><li><h4>Parameter files</h4>\n\
                   11827:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11828:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11829:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11830:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11831:  - Date and time at start: %s</ul>\n",\
                   11832:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11833:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11834:          fileres,fileres,\
                   11835:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11836:   fflush(fichtm);
                   11837: 
                   11838:   strcpy(pathr,path);
                   11839:   strcat(pathr,optionfilefiname);
1.184     brouard  11840: #ifdef WIN32
                   11841:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11842: #else
1.126     brouard  11843:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11844: #endif
                   11845:          
1.126     brouard  11846:   
1.220     brouard  11847:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11848:                 and for any valid combination of covariates
1.126     brouard  11849:      and prints on file fileres'p'. */
1.251     brouard  11850:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11851:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11852: 
                   11853:   fprintf(fichtm,"\n");
1.286     brouard  11854:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11855:          ftol, stepm);
                   11856:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11857:   ncurrv=1;
                   11858:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11859:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11860:   ncurrv=i;
                   11861:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11862:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  11863:   ncurrv=i;
                   11864:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11865:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  11866:   ncurrv=i;
                   11867:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11868:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11869:           nlstate, ndeath, maxwav, mle, weightopt);
                   11870: 
                   11871:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11872: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11873: 
                   11874:   
                   11875:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11876: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11877: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11878:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11879:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11880:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11881:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11882:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11883:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11884: 
1.126     brouard  11885:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11886:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11887:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11888: 
                   11889:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11890:   /* For mortality only */
1.126     brouard  11891:   if (mle==-3){
1.136     brouard  11892:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11893:     for(i=1;i<=NDIM;i++)
                   11894:       for(j=1;j<=NDIM;j++)
                   11895:        ximort[i][j]=0.;
1.186     brouard  11896:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  11897:     cens=ivector(firstobs,lastobs);
                   11898:     ageexmed=vector(firstobs,lastobs);
                   11899:     agecens=vector(firstobs,lastobs);
                   11900:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  11901:                
1.126     brouard  11902:     for (i=1; i<=imx; i++){
                   11903:       dcwave[i]=-1;
                   11904:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11905:        if (s[m][i]>nlstate) {
                   11906:          dcwave[i]=m;
                   11907:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11908:          break;
                   11909:        }
1.126     brouard  11910:     }
1.226     brouard  11911:     
1.126     brouard  11912:     for (i=1; i<=imx; i++) {
                   11913:       if (wav[i]>0){
1.226     brouard  11914:        ageexmed[i]=agev[mw[1][i]][i];
                   11915:        j=wav[i];
                   11916:        agecens[i]=1.; 
                   11917:        
                   11918:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11919:          agecens[i]=agev[mw[j][i]][i];
                   11920:          cens[i]= 1;
                   11921:        }else if (ageexmed[i]< 1) 
                   11922:          cens[i]= -1;
                   11923:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11924:          cens[i]=0 ;
1.126     brouard  11925:       }
                   11926:       else cens[i]=-1;
                   11927:     }
                   11928:     
                   11929:     for (i=1;i<=NDIM;i++) {
                   11930:       for (j=1;j<=NDIM;j++)
1.226     brouard  11931:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11932:     }
                   11933:     
1.302     brouard  11934:     p[1]=0.0268; p[NDIM]=0.083;
                   11935:     /* printf("%lf %lf", p[1], p[2]); */
1.126     brouard  11936:     
                   11937:     
1.136     brouard  11938: #ifdef GSL
                   11939:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11940: #else
1.126     brouard  11941:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11942: #endif
1.201     brouard  11943:     strcpy(filerespow,"POW-MORT_"); 
                   11944:     strcat(filerespow,fileresu);
1.126     brouard  11945:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11946:       printf("Problem with resultfile: %s\n", filerespow);
                   11947:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11948:     }
1.136     brouard  11949: #ifdef GSL
                   11950:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11951: #else
1.126     brouard  11952:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11953: #endif
1.126     brouard  11954:     /*  for (i=1;i<=nlstate;i++)
                   11955:        for(j=1;j<=nlstate+ndeath;j++)
                   11956:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11957:     */
                   11958:     fprintf(ficrespow,"\n");
1.136     brouard  11959: #ifdef GSL
                   11960:     /* gsl starts here */ 
                   11961:     T = gsl_multimin_fminimizer_nmsimplex;
                   11962:     gsl_multimin_fminimizer *sfm = NULL;
                   11963:     gsl_vector *ss, *x;
                   11964:     gsl_multimin_function minex_func;
                   11965: 
                   11966:     /* Initial vertex size vector */
                   11967:     ss = gsl_vector_alloc (NDIM);
                   11968:     
                   11969:     if (ss == NULL){
                   11970:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11971:     }
                   11972:     /* Set all step sizes to 1 */
                   11973:     gsl_vector_set_all (ss, 0.001);
                   11974: 
                   11975:     /* Starting point */
1.126     brouard  11976:     
1.136     brouard  11977:     x = gsl_vector_alloc (NDIM);
                   11978:     
                   11979:     if (x == NULL){
                   11980:       gsl_vector_free(ss);
                   11981:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11982:     }
                   11983:   
                   11984:     /* Initialize method and iterate */
                   11985:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11986:     /*     gsl_vector_set(x, 0, 0.0268); */
                   11987:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  11988:     gsl_vector_set(x, 0, p[1]);
                   11989:     gsl_vector_set(x, 1, p[2]);
                   11990: 
                   11991:     minex_func.f = &gompertz_f;
                   11992:     minex_func.n = NDIM;
                   11993:     minex_func.params = (void *)&p; /* ??? */
                   11994:     
                   11995:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   11996:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   11997:     
                   11998:     printf("Iterations beginning .....\n\n");
                   11999:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   12000: 
                   12001:     iteri=0;
                   12002:     while (rval == GSL_CONTINUE){
                   12003:       iteri++;
                   12004:       status = gsl_multimin_fminimizer_iterate(sfm);
                   12005:       
                   12006:       if (status) printf("error: %s\n", gsl_strerror (status));
                   12007:       fflush(0);
                   12008:       
                   12009:       if (status) 
                   12010:         break;
                   12011:       
                   12012:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   12013:       ssval = gsl_multimin_fminimizer_size (sfm);
                   12014:       
                   12015:       if (rval == GSL_SUCCESS)
                   12016:         printf ("converged to a local maximum at\n");
                   12017:       
                   12018:       printf("%5d ", iteri);
                   12019:       for (it = 0; it < NDIM; it++){
                   12020:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   12021:       }
                   12022:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   12023:     }
                   12024:     
                   12025:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   12026:     
                   12027:     gsl_vector_free(x); /* initial values */
                   12028:     gsl_vector_free(ss); /* inital step size */
                   12029:     for (it=0; it<NDIM; it++){
                   12030:       p[it+1]=gsl_vector_get(sfm->x,it);
                   12031:       fprintf(ficrespow," %.12lf", p[it]);
                   12032:     }
                   12033:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   12034: #endif
                   12035: #ifdef POWELL
                   12036:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   12037: #endif  
1.126     brouard  12038:     fclose(ficrespow);
                   12039:     
1.203     brouard  12040:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  12041: 
                   12042:     for(i=1; i <=NDIM; i++)
                   12043:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  12044:                                matcov[i][j]=matcov[j][i];
1.126     brouard  12045:     
                   12046:     printf("\nCovariance matrix\n ");
1.203     brouard  12047:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  12048:     for(i=1; i <=NDIM; i++) {
                   12049:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  12050:                                printf("%f ",matcov[i][j]);
                   12051:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  12052:       }
1.203     brouard  12053:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  12054:     }
                   12055:     
                   12056:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  12057:     for (i=1;i<=NDIM;i++) {
1.126     brouard  12058:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  12059:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   12060:     }
1.302     brouard  12061:     lsurv=vector(agegomp,AGESUP);
                   12062:     lpop=vector(agegomp,AGESUP);
                   12063:     tpop=vector(agegomp,AGESUP);
1.126     brouard  12064:     lsurv[agegomp]=100000;
                   12065:     
                   12066:     for (k=agegomp;k<=AGESUP;k++) {
                   12067:       agemortsup=k;
                   12068:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   12069:     }
                   12070:     
                   12071:     for (k=agegomp;k<agemortsup;k++)
                   12072:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   12073:     
                   12074:     for (k=agegomp;k<agemortsup;k++){
                   12075:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   12076:       sumlpop=sumlpop+lpop[k];
                   12077:     }
                   12078:     
                   12079:     tpop[agegomp]=sumlpop;
                   12080:     for (k=agegomp;k<(agemortsup-3);k++){
                   12081:       /*  tpop[k+1]=2;*/
                   12082:       tpop[k+1]=tpop[k]-lpop[k];
                   12083:     }
                   12084:     
                   12085:     
                   12086:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   12087:     for (k=agegomp;k<(agemortsup-2);k++) 
                   12088:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   12089:     
                   12090:     
                   12091:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  12092:                ageminpar=50;
                   12093:                agemaxpar=100;
1.194     brouard  12094:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   12095:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12096: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12097: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   12098:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12099: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12100: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12101:     }else{
                   12102:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   12103:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  12104:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  12105:                }
1.201     brouard  12106:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  12107:                     stepm, weightopt,\
                   12108:                     model,imx,p,matcov,agemortsup);
                   12109:     
1.302     brouard  12110:     free_vector(lsurv,agegomp,AGESUP);
                   12111:     free_vector(lpop,agegomp,AGESUP);
                   12112:     free_vector(tpop,agegomp,AGESUP);
1.220     brouard  12113:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  12114:     free_ivector(dcwave,firstobs,lastobs);
                   12115:     free_vector(agecens,firstobs,lastobs);
                   12116:     free_vector(ageexmed,firstobs,lastobs);
                   12117:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  12118: #ifdef GSL
1.136     brouard  12119: #endif
1.186     brouard  12120:   } /* Endof if mle==-3 mortality only */
1.205     brouard  12121:   /* Standard  */
                   12122:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   12123:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12124:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  12125:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  12126:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12127:     for (k=1; k<=npar;k++)
                   12128:       printf(" %d %8.5f",k,p[k]);
                   12129:     printf("\n");
1.205     brouard  12130:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   12131:       /* mlikeli uses func not funcone */
1.247     brouard  12132:       /* for(i=1;i<nlstate;i++){ */
                   12133:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   12134:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   12135:       /* } */
1.205     brouard  12136:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   12137:     }
                   12138:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   12139:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12140:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   12141:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12142:     }
                   12143:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  12144:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12145:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12146:     for (k=1; k<=npar;k++)
                   12147:       printf(" %d %8.5f",k,p[k]);
                   12148:     printf("\n");
                   12149:     
                   12150:     /*--------- results files --------------*/
1.283     brouard  12151:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12152:     
                   12153:     
                   12154:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12155:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12156:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12157:     for(i=1,jk=1; i <=nlstate; i++){
                   12158:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12159:        if (k != i) {
                   12160:          printf("%d%d ",i,k);
                   12161:          fprintf(ficlog,"%d%d ",i,k);
                   12162:          fprintf(ficres,"%1d%1d ",i,k);
                   12163:          for(j=1; j <=ncovmodel; j++){
                   12164:            printf("%12.7f ",p[jk]);
                   12165:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12166:            fprintf(ficres,"%12.7f ",p[jk]);
                   12167:            jk++; 
                   12168:          }
                   12169:          printf("\n");
                   12170:          fprintf(ficlog,"\n");
                   12171:          fprintf(ficres,"\n");
                   12172:        }
1.126     brouard  12173:       }
                   12174:     }
1.203     brouard  12175:     if(mle != 0){
                   12176:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12177:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12178:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12179:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12180:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12181:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12182:        for(k=1; k <=(nlstate+ndeath); k++){
                   12183:          if (k != i) {
                   12184:            printf("%d%d ",i,k);
                   12185:            fprintf(ficlog,"%d%d ",i,k);
                   12186:            for(j=1; j <=ncovmodel; j++){
                   12187:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12188:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12189:              jk++; 
                   12190:            }
                   12191:            printf("\n");
                   12192:            fprintf(ficlog,"\n");
                   12193:          }
                   12194:        }
1.193     brouard  12195:       }
1.203     brouard  12196:     } /* end of hesscov and Wald tests */
1.225     brouard  12197:     
1.203     brouard  12198:     /*  */
1.126     brouard  12199:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12200:     printf("# Scales (for hessian or gradient estimation)\n");
                   12201:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12202:     for(i=1,jk=1; i <=nlstate; i++){
                   12203:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12204:        if (j!=i) {
                   12205:          fprintf(ficres,"%1d%1d",i,j);
                   12206:          printf("%1d%1d",i,j);
                   12207:          fprintf(ficlog,"%1d%1d",i,j);
                   12208:          for(k=1; k<=ncovmodel;k++){
                   12209:            printf(" %.5e",delti[jk]);
                   12210:            fprintf(ficlog," %.5e",delti[jk]);
                   12211:            fprintf(ficres," %.5e",delti[jk]);
                   12212:            jk++;
                   12213:          }
                   12214:          printf("\n");
                   12215:          fprintf(ficlog,"\n");
                   12216:          fprintf(ficres,"\n");
                   12217:        }
1.126     brouard  12218:       }
                   12219:     }
                   12220:     
                   12221:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12222:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12223:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12224:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12225:     /* # 121 Var(a12)\n\ */
                   12226:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12227:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12228:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12229:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12230:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12231:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12232:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12233:     
                   12234:     
                   12235:     /* Just to have a covariance matrix which will be more understandable
                   12236:        even is we still don't want to manage dictionary of variables
                   12237:     */
                   12238:     for(itimes=1;itimes<=2;itimes++){
                   12239:       jj=0;
                   12240:       for(i=1; i <=nlstate; i++){
1.225     brouard  12241:        for(j=1; j <=nlstate+ndeath; j++){
                   12242:          if(j==i) continue;
                   12243:          for(k=1; k<=ncovmodel;k++){
                   12244:            jj++;
                   12245:            ca[0]= k+'a'-1;ca[1]='\0';
                   12246:            if(itimes==1){
                   12247:              if(mle>=1)
                   12248:                printf("#%1d%1d%d",i,j,k);
                   12249:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12250:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12251:            }else{
                   12252:              if(mle>=1)
                   12253:                printf("%1d%1d%d",i,j,k);
                   12254:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12255:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12256:            }
                   12257:            ll=0;
                   12258:            for(li=1;li <=nlstate; li++){
                   12259:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12260:                if(lj==li) continue;
                   12261:                for(lk=1;lk<=ncovmodel;lk++){
                   12262:                  ll++;
                   12263:                  if(ll<=jj){
                   12264:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12265:                    if(ll<jj){
                   12266:                      if(itimes==1){
                   12267:                        if(mle>=1)
                   12268:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12269:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12270:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12271:                      }else{
                   12272:                        if(mle>=1)
                   12273:                          printf(" %.5e",matcov[jj][ll]); 
                   12274:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12275:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12276:                      }
                   12277:                    }else{
                   12278:                      if(itimes==1){
                   12279:                        if(mle>=1)
                   12280:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12281:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12282:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12283:                      }else{
                   12284:                        if(mle>=1)
                   12285:                          printf(" %.7e",matcov[jj][ll]); 
                   12286:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12287:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12288:                      }
                   12289:                    }
                   12290:                  }
                   12291:                } /* end lk */
                   12292:              } /* end lj */
                   12293:            } /* end li */
                   12294:            if(mle>=1)
                   12295:              printf("\n");
                   12296:            fprintf(ficlog,"\n");
                   12297:            fprintf(ficres,"\n");
                   12298:            numlinepar++;
                   12299:          } /* end k*/
                   12300:        } /*end j */
1.126     brouard  12301:       } /* end i */
                   12302:     } /* end itimes */
                   12303:     
                   12304:     fflush(ficlog);
                   12305:     fflush(ficres);
1.225     brouard  12306:     while(fgets(line, MAXLINE, ficpar)) {
                   12307:       /* If line starts with a # it is a comment */
                   12308:       if (line[0] == '#') {
                   12309:        numlinepar++;
                   12310:        fputs(line,stdout);
                   12311:        fputs(line,ficparo);
                   12312:        fputs(line,ficlog);
1.299     brouard  12313:        fputs(line,ficres);
1.225     brouard  12314:        continue;
                   12315:       }else
                   12316:        break;
                   12317:     }
                   12318:     
1.209     brouard  12319:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12320:     /*   ungetc(c,ficpar); */
                   12321:     /*   fgets(line, MAXLINE, ficpar); */
                   12322:     /*   fputs(line,stdout); */
                   12323:     /*   fputs(line,ficparo); */
                   12324:     /* } */
                   12325:     /* ungetc(c,ficpar); */
1.126     brouard  12326:     
                   12327:     estepm=0;
1.209     brouard  12328:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12329:       
                   12330:       if (num_filled != 6) {
                   12331:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12332:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12333:        goto end;
                   12334:       }
                   12335:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12336:     }
                   12337:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12338:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12339:     
1.209     brouard  12340:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12341:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12342:     if (fage <= 2) {
                   12343:       bage = ageminpar;
                   12344:       fage = agemaxpar;
                   12345:     }
                   12346:     
                   12347:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12348:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12349:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12350:                
1.186     brouard  12351:     /* Other stuffs, more or less useful */    
1.254     brouard  12352:     while(fgets(line, MAXLINE, ficpar)) {
                   12353:       /* If line starts with a # it is a comment */
                   12354:       if (line[0] == '#') {
                   12355:        numlinepar++;
                   12356:        fputs(line,stdout);
                   12357:        fputs(line,ficparo);
                   12358:        fputs(line,ficlog);
1.299     brouard  12359:        fputs(line,ficres);
1.254     brouard  12360:        continue;
                   12361:       }else
                   12362:        break;
                   12363:     }
                   12364: 
                   12365:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12366:       
                   12367:       if (num_filled != 7) {
                   12368:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12369:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12370:        goto end;
                   12371:       }
                   12372:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12373:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12374:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12375:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12376:     }
1.254     brouard  12377: 
                   12378:     while(fgets(line, MAXLINE, ficpar)) {
                   12379:       /* If line starts with a # it is a comment */
                   12380:       if (line[0] == '#') {
                   12381:        numlinepar++;
                   12382:        fputs(line,stdout);
                   12383:        fputs(line,ficparo);
                   12384:        fputs(line,ficlog);
1.299     brouard  12385:        fputs(line,ficres);
1.254     brouard  12386:        continue;
                   12387:       }else
                   12388:        break;
1.126     brouard  12389:     }
                   12390:     
                   12391:     
                   12392:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12393:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12394:     
1.254     brouard  12395:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12396:       if (num_filled != 1) {
                   12397:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12398:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12399:        goto end;
                   12400:       }
                   12401:       printf("pop_based=%d\n",popbased);
                   12402:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12403:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12404:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12405:     }
                   12406:      
1.258     brouard  12407:     /* Results */
                   12408:     nresult=0;
                   12409:     do{
                   12410:       if(!fgets(line, MAXLINE, ficpar)){
                   12411:        endishere=1;
                   12412:        parameterline=14;
                   12413:       }else if (line[0] == '#') {
                   12414:        /* If line starts with a # it is a comment */
1.254     brouard  12415:        numlinepar++;
                   12416:        fputs(line,stdout);
                   12417:        fputs(line,ficparo);
                   12418:        fputs(line,ficlog);
1.299     brouard  12419:        fputs(line,ficres);
1.254     brouard  12420:        continue;
1.258     brouard  12421:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12422:        parameterline=11;
1.296     brouard  12423:       else if(sscanf(line,"prevbackcast=%[^\n]\n",modeltemp))
1.258     brouard  12424:        parameterline=12;
                   12425:       else if(sscanf(line,"result:%[^\n]\n",modeltemp))
                   12426:        parameterline=13;
                   12427:       else{
                   12428:        parameterline=14;
1.254     brouard  12429:       }
1.258     brouard  12430:       switch (parameterline){ 
                   12431:       case 11:
1.296     brouard  12432:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12433:                  fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.258     brouard  12434:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12435:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12436:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12437:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12438:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12439:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
1.296     brouard  12440:           prvforecast = 1;
                   12441:        } 
                   12442:        else if((num_filled=sscanf(line,"prevforecast=%d yearsfproj=%lf mobil_average=%d\n",&prevfcast,&yrfproj,&mobilavproj)) !=EOF){/* && (num_filled == 3))*/
1.302     brouard  12443:          printf("prevforecast=%d yearsfproj=%lf.2 mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12444:          fprintf(ficlog,"prevforecast=%d yearsfproj=%lf.2 mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12445:          fprintf(ficres,"prevforecast=%d yearsfproj=%lf.2 mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
1.296     brouard  12446:           prvforecast = 2;
                   12447:        }
                   12448:        else {
                   12449:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearsfproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12450:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12451:          goto end;
1.258     brouard  12452:        }
1.254     brouard  12453:        break;
1.258     brouard  12454:       case 12:
1.296     brouard  12455:        if((num_filled=sscanf(line,"prevbackcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&prevbcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12456:           fprintf(ficparo,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12457:          printf("prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12458:          fprintf(ficlog,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12459:          fprintf(ficres,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12460:          /* day and month of back2 are not used but only year anback2.*/
1.273     brouard  12461:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12462:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.296     brouard  12463:           prvbackcast = 1;
                   12464:        } 
                   12465:        else if((num_filled=sscanf(line,"prevbackcast=%d yearsbproj=%lf mobil_average=%d\n",&prevbcast,&yrbproj,&mobilavproj)) ==3){/* && (num_filled == 3))*/
1.302     brouard  12466:          printf("prevbackcast=%d yearsbproj=%lf.2 mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12467:          fprintf(ficlog,"prevbackcast=%d yearsbproj=%lf.2 mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12468:          fprintf(ficres,"prevbackcast=%d yearsbproj=%lf.2 mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
1.296     brouard  12469:           prvbackcast = 2;
                   12470:        }
                   12471:        else {
                   12472:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearsbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12473:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12474:          goto end;
1.258     brouard  12475:        }
1.230     brouard  12476:        break;
1.258     brouard  12477:       case 13:
                   12478:        if((num_filled=sscanf(line,"result:%[^\n]\n",resultline)) !=EOF){
                   12479:          if (num_filled == 0){
                   12480:            resultline[0]='\0';
                   12481:            printf("Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12482:            fprintf(ficlog,"Warning %d: no result line! It should be at minimum 'result: V2=0 V1=1 or result:.\n%s\n", num_filled, line);
                   12483:            break;
                   12484:          } else if (num_filled != 1){
                   12485:            printf("ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12486:            fprintf(ficlog,"ERROR %d: result line! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",num_filled, line);
                   12487:          }
                   12488:          nresult++; /* Sum of resultlines */
                   12489:          printf("Result %d: result=%s\n",nresult, resultline);
                   12490:          if(nresult > MAXRESULTLINES){
                   12491:            printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12492:            fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\n",MAXRESULTLINES,nresult);
                   12493:            goto end;
                   12494:          }
                   12495:          decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12496:          fprintf(ficparo,"result: %s\n",resultline);
                   12497:          fprintf(ficres,"result: %s\n",resultline);
                   12498:          fprintf(ficlog,"result: %s\n",resultline);
1.230     brouard  12499:          break;
1.303     brouard  12500:        case 14:
                   12501:          printf("Error: Unknown command '%s'\n",line);
                   12502:          fprintf(ficlog,"Error: Unknown command '%s'\n",line);
                   12503:          if(ncovmodel >=2 && nresult==0 ){
1.259     brouard  12504:            printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.303     brouard  12505:            fprintf(ficlog,"ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12506:          }
1.303     brouard  12507:          goto end;
1.259     brouard  12508:          break;
1.258     brouard  12509:        default:
                   12510:          nresult=1;
                   12511:          decoderesult(".",nresult ); /* No covariate */
                   12512:        }
                   12513:       } /* End switch parameterline */
                   12514:     }while(endishere==0); /* End do */
1.126     brouard  12515:     
1.230     brouard  12516:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12517:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12518:     
                   12519:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12520:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12521:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12522: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12523: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12524:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12525: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12526: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12527:     }else{
1.270     brouard  12528:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
1.296     brouard  12529:       /* It seems that anprojd which is computed from the mean year at interview which is known yet because of freqsummary */
                   12530:       /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */ /* Done in freqsummary */
                   12531:       if(prvforecast==1){
                   12532:         dateprojd=(jproj1+12*mproj1+365*anproj1)/365;
                   12533:         jprojd=jproj1;
                   12534:         mprojd=mproj1;
                   12535:         anprojd=anproj1;
                   12536:         dateprojf=(jproj2+12*mproj2+365*anproj2)/365;
                   12537:         jprojf=jproj2;
                   12538:         mprojf=mproj2;
                   12539:         anprojf=anproj2;
                   12540:       } else if(prvforecast == 2){
                   12541:         dateprojd=dateintmean;
                   12542:         date2dmy(dateprojd,&jprojd, &mprojd, &anprojd);
                   12543:         dateprojf=dateintmean+yrfproj;
                   12544:         date2dmy(dateprojf,&jprojf, &mprojf, &anprojf);
                   12545:       }
                   12546:       if(prvbackcast==1){
                   12547:         datebackd=(jback1+12*mback1+365*anback1)/365;
                   12548:         jbackd=jback1;
                   12549:         mbackd=mback1;
                   12550:         anbackd=anback1;
                   12551:         datebackf=(jback2+12*mback2+365*anback2)/365;
                   12552:         jbackf=jback2;
                   12553:         mbackf=mback2;
                   12554:         anbackf=anback2;
                   12555:       } else if(prvbackcast == 2){
                   12556:         datebackd=dateintmean;
                   12557:         date2dmy(datebackd,&jbackd, &mbackd, &anbackd);
                   12558:         datebackf=dateintmean-yrbproj;
                   12559:         date2dmy(datebackf,&jbackf, &mbackf, &anbackf);
                   12560:       }
                   12561:       
                   12562:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, prevbcast, pathc,p, (int)anprojd-bage, (int)anbackd-fage);
1.220     brouard  12563:     }
                   12564:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.296     brouard  12565:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,prevbcast, estepm, \
                   12566:                 jprev1,mprev1,anprev1,dateprev1, dateprojd, datebackd,jprev2,mprev2,anprev2,dateprev2,dateprojf, datebackf);
1.220     brouard  12567:                
1.225     brouard  12568:     /*------------ free_vector  -------------*/
                   12569:     /*  chdir(path); */
1.220     brouard  12570:                
1.215     brouard  12571:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12572:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12573:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12574:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12575:     free_lvector(num,firstobs,lastobs);
                   12576:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12577:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12578:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12579:     fclose(ficparo);
                   12580:     fclose(ficres);
1.220     brouard  12581:                
                   12582:                
1.186     brouard  12583:     /* Other results (useful)*/
1.220     brouard  12584:                
                   12585:                
1.126     brouard  12586:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12587:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12588:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12589:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12590:     fclose(ficrespl);
                   12591: 
                   12592:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12593:     /*#include "hpijx.h"*/
                   12594:     hPijx(p, bage, fage);
1.145     brouard  12595:     fclose(ficrespij);
1.227     brouard  12596:     
1.220     brouard  12597:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12598:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12599:     k=1;
1.126     brouard  12600:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12601:     
1.269     brouard  12602:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12603:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12604:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12605:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12606:        for(k=1;k<=ncovcombmax;k++)
                   12607:          probs[i][j][k]=0.;
1.269     brouard  12608:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12609:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12610:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12611:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12612:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12613:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12614:          for(k=1;k<=ncovcombmax;k++)
                   12615:            mobaverages[i][j][k]=0.;
1.219     brouard  12616:       mobaverage=mobaverages;
                   12617:       if (mobilav!=0) {
1.235     brouard  12618:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12619:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12620:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12621:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12622:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12623:        }
1.269     brouard  12624:       } else if (mobilavproj !=0) {
1.235     brouard  12625:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12626:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12627:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12628:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12629:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12630:        }
1.269     brouard  12631:       }else{
                   12632:        printf("Internal error moving average\n");
                   12633:        fflush(stdout);
                   12634:        exit(1);
1.219     brouard  12635:       }
                   12636:     }/* end if moving average */
1.227     brouard  12637:     
1.126     brouard  12638:     /*---------- Forecasting ------------------*/
1.296     brouard  12639:     if(prevfcast==1){ 
                   12640:       /*   /\*    if(stepm ==1){*\/ */
                   12641:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12642:       /*This done previously after freqsummary.*/
                   12643:       /*   dateprojd=(jproj1+12*mproj1+365*anproj1)/365; */
                   12644:       /*   dateprojf=(jproj2+12*mproj2+365*anproj2)/365; */
                   12645:       
                   12646:       /* } else if (prvforecast==2){ */
                   12647:       /*   /\*    if(stepm ==1){*\/ */
                   12648:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12649:       /* } */
                   12650:       /*prevforecast(fileresu, dateintmean, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);*/
                   12651:       prevforecast(fileresu,dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, p, cptcoveff);
1.126     brouard  12652:     }
1.269     brouard  12653: 
1.296     brouard  12654:     /* Prevbcasting */
                   12655:     if(prevbcast==1){
1.219     brouard  12656:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12657:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12658:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12659: 
                   12660:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12661: 
                   12662:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12663: 
1.219     brouard  12664:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12665:       fclose(ficresplb);
                   12666: 
1.222     brouard  12667:       hBijx(p, bage, fage, mobaverage);
                   12668:       fclose(ficrespijb);
1.219     brouard  12669: 
1.296     brouard  12670:       /* /\* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, *\/ */
                   12671:       /* /\*                  mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); *\/ */
                   12672:       /* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, */
                   12673:       /*                      mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
                   12674:       prevbackforecast(fileresu, mobaverage, dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2,
                   12675:                       mobilavproj, bage, fage, firstpass, lastpass, p, cptcoveff);
                   12676: 
                   12677:       
1.269     brouard  12678:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12679: 
                   12680:       
1.269     brouard  12681:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12682:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12683:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12684:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.296     brouard  12685:     }    /* end  Prevbcasting */
1.268     brouard  12686:  
1.186     brouard  12687:  
                   12688:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12689: 
1.215     brouard  12690:     free_ivector(wav,1,imx);
                   12691:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12692:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12693:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12694:                
                   12695:                
1.127     brouard  12696:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12697:                
1.201     brouard  12698:     strcpy(filerese,"E_");
                   12699:     strcat(filerese,fileresu);
1.126     brouard  12700:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12701:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12702:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12703:     }
1.208     brouard  12704:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12705:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12706: 
                   12707:     pstamp(ficreseij);
1.219     brouard  12708:                
1.235     brouard  12709:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12710:     if (cptcovn < 1){i1=1;}
                   12711:     
                   12712:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12713:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12714:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12715:        continue;
1.219     brouard  12716:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12717:       printf("\n#****** ");
1.225     brouard  12718:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12719:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12720:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12721:       }
                   12722:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12723:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12724:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12725:       }
                   12726:       fprintf(ficreseij,"******\n");
1.235     brouard  12727:       printf("******\n");
1.219     brouard  12728:       
                   12729:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12730:       oldm=oldms;savm=savms;
1.235     brouard  12731:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12732:       
1.219     brouard  12733:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12734:     }
                   12735:     fclose(ficreseij);
1.208     brouard  12736:     printf("done evsij\n");fflush(stdout);
                   12737:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12738: 
1.218     brouard  12739:                
1.227     brouard  12740:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12741:                
1.201     brouard  12742:     strcpy(filerest,"T_");
                   12743:     strcat(filerest,fileresu);
1.127     brouard  12744:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12745:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12746:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12747:     }
1.208     brouard  12748:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12749:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12750:     strcpy(fileresstde,"STDE_");
                   12751:     strcat(fileresstde,fileresu);
1.126     brouard  12752:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12753:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12754:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12755:     }
1.227     brouard  12756:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12757:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12758: 
1.201     brouard  12759:     strcpy(filerescve,"CVE_");
                   12760:     strcat(filerescve,fileresu);
1.126     brouard  12761:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12762:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12763:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12764:     }
1.227     brouard  12765:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12766:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12767: 
1.201     brouard  12768:     strcpy(fileresv,"V_");
                   12769:     strcat(fileresv,fileresu);
1.126     brouard  12770:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12771:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12772:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12773:     }
1.227     brouard  12774:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12775:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12776: 
1.235     brouard  12777:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12778:     if (cptcovn < 1){i1=1;}
                   12779:     
                   12780:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12781:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12782:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12783:        continue;
1.242     brouard  12784:       printf("\n#****** Result for:");
                   12785:       fprintf(ficrest,"\n#****** Result for:");
                   12786:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12787:       for(j=1;j<=cptcoveff;j++){ 
                   12788:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12789:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12790:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12791:       }
1.235     brouard  12792:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12793:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12794:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12795:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12796:       }        
1.208     brouard  12797:       fprintf(ficrest,"******\n");
1.227     brouard  12798:       fprintf(ficlog,"******\n");
                   12799:       printf("******\n");
1.208     brouard  12800:       
                   12801:       fprintf(ficresstdeij,"\n#****** ");
                   12802:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12803:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12804:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12805:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12806:       }
1.235     brouard  12807:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12808:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12809:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12810:       }        
1.208     brouard  12811:       fprintf(ficresstdeij,"******\n");
                   12812:       fprintf(ficrescveij,"******\n");
                   12813:       
                   12814:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12815:       /* pstamp(ficresvij); */
1.225     brouard  12816:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12817:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12818:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12819:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12820:       }        
1.208     brouard  12821:       fprintf(ficresvij,"******\n");
                   12822:       
                   12823:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12824:       oldm=oldms;savm=savms;
1.235     brouard  12825:       printf(" cvevsij ");
                   12826:       fprintf(ficlog, " cvevsij ");
                   12827:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12828:       printf(" end cvevsij \n ");
                   12829:       fprintf(ficlog, " end cvevsij \n ");
                   12830:       
                   12831:       /*
                   12832:        */
                   12833:       /* goto endfree; */
                   12834:       
                   12835:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12836:       pstamp(ficrest);
                   12837:       
1.269     brouard  12838:       epj=vector(1,nlstate+1);
1.208     brouard  12839:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12840:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12841:        cptcod= 0; /* To be deleted */
                   12842:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12843:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12844:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12845:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12846:        if(vpopbased==1)
                   12847:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12848:        else
1.288     brouard  12849:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12850:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12851:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12852:        fprintf(ficrest,"\n");
                   12853:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  12854:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   12855:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12856:        for(age=bage; age <=fage ;age++){
1.235     brouard  12857:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12858:          if (vpopbased==1) {
                   12859:            if(mobilav ==0){
                   12860:              for(i=1; i<=nlstate;i++)
                   12861:                prlim[i][i]=probs[(int)age][i][k];
                   12862:            }else{ /* mobilav */ 
                   12863:              for(i=1; i<=nlstate;i++)
                   12864:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12865:            }
                   12866:          }
1.219     brouard  12867:          
1.227     brouard  12868:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12869:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12870:          /* printf(" age %4.0f ",age); */
                   12871:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12872:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12873:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12874:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12875:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12876:            }
                   12877:            epj[nlstate+1] +=epj[j];
                   12878:          }
                   12879:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12880:          
1.227     brouard  12881:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12882:            for(j=1;j <=nlstate;j++)
                   12883:              vepp += vareij[i][j][(int)age];
                   12884:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12885:          for(j=1;j <=nlstate;j++){
                   12886:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12887:          }
                   12888:          fprintf(ficrest,"\n");
                   12889:        }
1.208     brouard  12890:       } /* End vpopbased */
1.269     brouard  12891:       free_vector(epj,1,nlstate+1);
1.208     brouard  12892:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12893:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12894:       printf("done selection\n");fflush(stdout);
                   12895:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12896:       
1.235     brouard  12897:     } /* End k selection */
1.227     brouard  12898: 
                   12899:     printf("done State-specific expectancies\n");fflush(stdout);
                   12900:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12901: 
1.288     brouard  12902:     /* variance-covariance of forward period prevalence*/
1.269     brouard  12903:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12904: 
1.227     brouard  12905:     
1.290     brouard  12906:     free_vector(weight,firstobs,lastobs);
1.227     brouard  12907:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  12908:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   12909:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   12910:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   12911:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  12912:     free_ivector(tab,1,NCOVMAX);
                   12913:     fclose(ficresstdeij);
                   12914:     fclose(ficrescveij);
                   12915:     fclose(ficresvij);
                   12916:     fclose(ficrest);
                   12917:     fclose(ficpar);
                   12918:     
                   12919:     
1.126     brouard  12920:     /*---------- End : free ----------------*/
1.219     brouard  12921:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12922:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12923:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12924:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12925:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12926:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12927:   /* endfree:*/
                   12928:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12929:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12930:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  12931:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   12932:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   12933:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   12934:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  12935:   free_matrix(matcov,1,npar,1,npar);
                   12936:   free_matrix(hess,1,npar,1,npar);
                   12937:   /*free_vector(delti,1,npar);*/
                   12938:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12939:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12940:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12941:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12942:   
                   12943:   free_ivector(ncodemax,1,NCOVMAX);
                   12944:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12945:   free_ivector(Dummy,-1,NCOVMAX);
                   12946:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12947:   free_ivector(DummyV,1,NCOVMAX);
                   12948:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12949:   free_ivector(Typevar,-1,NCOVMAX);
                   12950:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12951:   free_ivector(TvarsQ,1,NCOVMAX);
                   12952:   free_ivector(TvarsQind,1,NCOVMAX);
                   12953:   free_ivector(TvarsD,1,NCOVMAX);
                   12954:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12955:   free_ivector(TvarFD,1,NCOVMAX);
                   12956:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12957:   free_ivector(TvarF,1,NCOVMAX);
                   12958:   free_ivector(TvarFind,1,NCOVMAX);
                   12959:   free_ivector(TvarV,1,NCOVMAX);
                   12960:   free_ivector(TvarVind,1,NCOVMAX);
                   12961:   free_ivector(TvarA,1,NCOVMAX);
                   12962:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12963:   free_ivector(TvarFQ,1,NCOVMAX);
                   12964:   free_ivector(TvarFQind,1,NCOVMAX);
                   12965:   free_ivector(TvarVD,1,NCOVMAX);
                   12966:   free_ivector(TvarVDind,1,NCOVMAX);
                   12967:   free_ivector(TvarVQ,1,NCOVMAX);
                   12968:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12969:   free_ivector(Tvarsel,1,NCOVMAX);
                   12970:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12971:   free_ivector(Tposprod,1,NCOVMAX);
                   12972:   free_ivector(Tprod,1,NCOVMAX);
                   12973:   free_ivector(Tvaraff,1,NCOVMAX);
                   12974:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12975:   free_ivector(Tage,1,NCOVMAX);
                   12976:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12977:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12978:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12979:   
                   12980:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12981:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12982:   fflush(fichtm);
                   12983:   fflush(ficgp);
                   12984:   
1.227     brouard  12985:   
1.126     brouard  12986:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12987:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12988:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12989:   }else{
                   12990:     printf("End of Imach\n");
                   12991:     fprintf(ficlog,"End of Imach\n");
                   12992:   }
                   12993:   printf("See log file on %s\n",filelog);
                   12994:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  12995:   /*(void) gettimeofday(&end_time,&tzp);*/
                   12996:   rend_time = time(NULL);  
                   12997:   end_time = *localtime(&rend_time);
                   12998:   /* tml = *localtime(&end_time.tm_sec); */
                   12999:   strcpy(strtend,asctime(&end_time));
1.126     brouard  13000:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   13001:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  13002:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  13003:   
1.157     brouard  13004:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   13005:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   13006:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  13007:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   13008: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   13009:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13010:   fclose(fichtm);
                   13011:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13012:   fclose(fichtmcov);
                   13013:   fclose(ficgp);
                   13014:   fclose(ficlog);
                   13015:   /*------ End -----------*/
1.227     brouard  13016:   
1.281     brouard  13017: 
                   13018: /* Executes gnuplot */
1.227     brouard  13019:   
                   13020:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  13021: #ifdef WIN32
1.227     brouard  13022:   if (_chdir(pathcd) != 0)
                   13023:     printf("Can't move to directory %s!\n",path);
                   13024:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  13025: #else
1.227     brouard  13026:     if(chdir(pathcd) != 0)
                   13027:       printf("Can't move to directory %s!\n", path);
                   13028:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  13029: #endif 
1.126     brouard  13030:     printf("Current directory %s!\n",pathcd);
                   13031:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   13032:   sprintf(plotcmd,"gnuplot");
1.157     brouard  13033: #ifdef _WIN32
1.126     brouard  13034:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   13035: #endif
                   13036:   if(!stat(plotcmd,&info)){
1.158     brouard  13037:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13038:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  13039:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  13040:     }else
                   13041:       strcpy(pplotcmd,plotcmd);
1.157     brouard  13042: #ifdef __unix
1.126     brouard  13043:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   13044:     if(!stat(plotcmd,&info)){
1.158     brouard  13045:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13046:     }else
                   13047:       strcpy(pplotcmd,plotcmd);
                   13048: #endif
                   13049:   }else
                   13050:     strcpy(pplotcmd,plotcmd);
                   13051:   
                   13052:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  13053:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292     brouard  13054:   strcpy(pplotcmd,plotcmd);
1.227     brouard  13055:   
1.126     brouard  13056:   if((outcmd=system(plotcmd)) != 0){
1.292     brouard  13057:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  13058:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  13059:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292     brouard  13060:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  13061:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292     brouard  13062:       strcpy(plotcmd,pplotcmd);
                   13063:     }
1.126     brouard  13064:   }
1.158     brouard  13065:   printf(" Successful, please wait...");
1.126     brouard  13066:   while (z[0] != 'q') {
                   13067:     /* chdir(path); */
1.154     brouard  13068:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  13069:     scanf("%s",z);
                   13070: /*     if (z[0] == 'c') system("./imach"); */
                   13071:     if (z[0] == 'e') {
1.158     brouard  13072: #ifdef __APPLE__
1.152     brouard  13073:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  13074: #elif __linux
                   13075:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  13076: #else
1.152     brouard  13077:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  13078: #endif
                   13079:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   13080:       system(pplotcmd);
1.126     brouard  13081:     }
                   13082:     else if (z[0] == 'g') system(plotcmd);
                   13083:     else if (z[0] == 'q') exit(0);
                   13084:   }
1.227     brouard  13085: end:
1.126     brouard  13086:   while (z[0] != 'q') {
1.195     brouard  13087:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  13088:     scanf("%s",z);
                   13089:   }
1.283     brouard  13090:   printf("End\n");
1.282     brouard  13091:   exit(0);
1.126     brouard  13092: }

FreeBSD-CVSweb <freebsd-cvsweb@FreeBSD.org>