Annotation of imach/src/imach.c, revision 1.308

1.308   ! brouard     1: /* $Id: imach.c,v 1.307 2021/03/08 18:11:32 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.308   ! brouard     4:   Revision 1.307  2021/03/08 18:11:32  brouard
        !             5:   Summary: 0.99r22 fixed bug on result:
        !             6: 
1.307     brouard     7:   Revision 1.306  2021/02/20 15:44:02  brouard
                      8:   Summary: Version 0.99r21
                      9: 
                     10:   * imach.c (Module): Fix bug on quitting after result lines!
                     11:   (Module): Version 0.99r21
                     12: 
1.306     brouard    13:   Revision 1.305  2021/02/20 15:28:30  brouard
                     14:   * imach.c (Module): Fix bug on quitting after result lines!
                     15: 
1.305     brouard    16:   Revision 1.304  2021/02/12 11:34:20  brouard
                     17:   * imach.c (Module): The use of a Windows BOM (huge) file is now an error
                     18: 
1.304     brouard    19:   Revision 1.303  2021/02/11 19:50:15  brouard
                     20:   *  (Module): imach.c Someone entered 'results:' instead of 'result:'. Now it is an error which is printed.
                     21: 
1.303     brouard    22:   Revision 1.302  2020/02/22 21:00:05  brouard
                     23:   *  (Module): imach.c Update mle=-3 (for computing Life expectancy
                     24:   and life table from the data without any state)
                     25: 
1.302     brouard    26:   Revision 1.301  2019/06/04 13:51:20  brouard
                     27:   Summary: Error in 'r'parameter file backcast yearsbproj instead of yearsfproj
                     28: 
1.301     brouard    29:   Revision 1.300  2019/05/22 19:09:45  brouard
                     30:   Summary: version 0.99r19 of May 2019
                     31: 
1.300     brouard    32:   Revision 1.299  2019/05/22 18:37:08  brouard
                     33:   Summary: Cleaned 0.99r19
                     34: 
1.299     brouard    35:   Revision 1.298  2019/05/22 18:19:56  brouard
                     36:   *** empty log message ***
                     37: 
1.298     brouard    38:   Revision 1.297  2019/05/22 17:56:10  brouard
                     39:   Summary: Fix bug by moving date2dmy and nhstepm which gaefin=-1
                     40: 
1.297     brouard    41:   Revision 1.296  2019/05/20 13:03:18  brouard
                     42:   Summary: Projection syntax simplified
                     43: 
                     44: 
                     45:   We can now start projections, forward or backward, from the mean date
                     46:   of inteviews up to or down to a number of years of projection:
                     47:   prevforecast=1 yearsfproj=15.3 mobil_average=0
                     48:   or
                     49:   prevforecast=1 starting-proj-date=1/1/2007 final-proj-date=12/31/2017 mobil_average=0
                     50:   or
                     51:   prevbackcast=1 yearsbproj=12.3 mobil_average=1
                     52:   or
                     53:   prevbackcast=1 starting-back-date=1/10/1999 final-back-date=1/1/1985 mobil_average=1
                     54: 
1.296     brouard    55:   Revision 1.295  2019/05/18 09:52:50  brouard
                     56:   Summary: doxygen tex bug
                     57: 
1.295     brouard    58:   Revision 1.294  2019/05/16 14:54:33  brouard
                     59:   Summary: There was some wrong lines added
                     60: 
1.294     brouard    61:   Revision 1.293  2019/05/09 15:17:34  brouard
                     62:   *** empty log message ***
                     63: 
1.293     brouard    64:   Revision 1.292  2019/05/09 14:17:20  brouard
                     65:   Summary: Some updates
                     66: 
1.292     brouard    67:   Revision 1.291  2019/05/09 13:44:18  brouard
                     68:   Summary: Before ncovmax
                     69: 
1.291     brouard    70:   Revision 1.290  2019/05/09 13:39:37  brouard
                     71:   Summary: 0.99r18 unlimited number of individuals
                     72: 
                     73:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                     74: 
1.290     brouard    75:   Revision 1.289  2018/12/13 09:16:26  brouard
                     76:   Summary: Bug for young ages (<-30) will be in r17
                     77: 
1.289     brouard    78:   Revision 1.288  2018/05/02 20:58:27  brouard
                     79:   Summary: Some bugs fixed
                     80: 
1.288     brouard    81:   Revision 1.287  2018/05/01 17:57:25  brouard
                     82:   Summary: Bug fixed by providing frequencies only for non missing covariates
                     83: 
1.287     brouard    84:   Revision 1.286  2018/04/27 14:27:04  brouard
                     85:   Summary: some minor bugs
                     86: 
1.286     brouard    87:   Revision 1.285  2018/04/21 21:02:16  brouard
                     88:   Summary: Some bugs fixed, valgrind tested
                     89: 
1.285     brouard    90:   Revision 1.284  2018/04/20 05:22:13  brouard
                     91:   Summary: Computing mean and stdeviation of fixed quantitative variables
                     92: 
1.284     brouard    93:   Revision 1.283  2018/04/19 14:49:16  brouard
                     94:   Summary: Some minor bugs fixed
                     95: 
1.283     brouard    96:   Revision 1.282  2018/02/27 22:50:02  brouard
                     97:   *** empty log message ***
                     98: 
1.282     brouard    99:   Revision 1.281  2018/02/27 19:25:23  brouard
                    100:   Summary: Adding second argument for quitting
                    101: 
1.281     brouard   102:   Revision 1.280  2018/02/21 07:58:13  brouard
                    103:   Summary: 0.99r15
                    104: 
                    105:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                    106: 
1.280     brouard   107:   Revision 1.279  2017/07/20 13:35:01  brouard
                    108:   Summary: temporary working
                    109: 
1.279     brouard   110:   Revision 1.278  2017/07/19 14:09:02  brouard
                    111:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                    112: 
1.278     brouard   113:   Revision 1.277  2017/07/17 08:53:49  brouard
                    114:   Summary: BOM files can be read now
                    115: 
1.277     brouard   116:   Revision 1.276  2017/06/30 15:48:31  brouard
                    117:   Summary: Graphs improvements
                    118: 
1.276     brouard   119:   Revision 1.275  2017/06/30 13:39:33  brouard
                    120:   Summary: Saito's color
                    121: 
1.275     brouard   122:   Revision 1.274  2017/06/29 09:47:08  brouard
                    123:   Summary: Version 0.99r14
                    124: 
1.274     brouard   125:   Revision 1.273  2017/06/27 11:06:02  brouard
                    126:   Summary: More documentation on projections
                    127: 
1.273     brouard   128:   Revision 1.272  2017/06/27 10:22:40  brouard
                    129:   Summary: Color of backprojection changed from 6 to 5(yellow)
                    130: 
1.272     brouard   131:   Revision 1.271  2017/06/27 10:17:50  brouard
                    132:   Summary: Some bug with rint
                    133: 
1.271     brouard   134:   Revision 1.270  2017/05/24 05:45:29  brouard
                    135:   *** empty log message ***
                    136: 
1.270     brouard   137:   Revision 1.269  2017/05/23 08:39:25  brouard
                    138:   Summary: Code into subroutine, cleanings
                    139: 
1.269     brouard   140:   Revision 1.268  2017/05/18 20:09:32  brouard
                    141:   Summary: backprojection and confidence intervals of backprevalence
                    142: 
1.268     brouard   143:   Revision 1.267  2017/05/13 10:25:05  brouard
                    144:   Summary: temporary save for backprojection
                    145: 
1.267     brouard   146:   Revision 1.266  2017/05/13 07:26:12  brouard
                    147:   Summary: Version 0.99r13 (improvements and bugs fixed)
                    148: 
1.266     brouard   149:   Revision 1.265  2017/04/26 16:22:11  brouard
                    150:   Summary: imach 0.99r13 Some bugs fixed
                    151: 
1.265     brouard   152:   Revision 1.264  2017/04/26 06:01:29  brouard
                    153:   Summary: Labels in graphs
                    154: 
1.264     brouard   155:   Revision 1.263  2017/04/24 15:23:15  brouard
                    156:   Summary: to save
                    157: 
1.263     brouard   158:   Revision 1.262  2017/04/18 16:48:12  brouard
                    159:   *** empty log message ***
                    160: 
1.262     brouard   161:   Revision 1.261  2017/04/05 10:14:09  brouard
                    162:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    163: 
1.261     brouard   164:   Revision 1.260  2017/04/04 17:46:59  brouard
                    165:   Summary: Gnuplot indexations fixed (humm)
                    166: 
1.260     brouard   167:   Revision 1.259  2017/04/04 13:01:16  brouard
                    168:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    169: 
1.259     brouard   170:   Revision 1.258  2017/04/03 10:17:47  brouard
                    171:   Summary: Version 0.99r12
                    172: 
                    173:   Some cleanings, conformed with updated documentation.
                    174: 
1.258     brouard   175:   Revision 1.257  2017/03/29 16:53:30  brouard
                    176:   Summary: Temp
                    177: 
1.257     brouard   178:   Revision 1.256  2017/03/27 05:50:23  brouard
                    179:   Summary: Temporary
                    180: 
1.256     brouard   181:   Revision 1.255  2017/03/08 16:02:28  brouard
                    182:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    183: 
1.255     brouard   184:   Revision 1.254  2017/03/08 07:13:00  brouard
                    185:   Summary: Fixing data parameter line
                    186: 
1.254     brouard   187:   Revision 1.253  2016/12/15 11:59:41  brouard
                    188:   Summary: 0.99 in progress
                    189: 
1.253     brouard   190:   Revision 1.252  2016/09/15 21:15:37  brouard
                    191:   *** empty log message ***
                    192: 
1.252     brouard   193:   Revision 1.251  2016/09/15 15:01:13  brouard
                    194:   Summary: not working
                    195: 
1.251     brouard   196:   Revision 1.250  2016/09/08 16:07:27  brouard
                    197:   Summary: continue
                    198: 
1.250     brouard   199:   Revision 1.249  2016/09/07 17:14:18  brouard
                    200:   Summary: Starting values from frequencies
                    201: 
1.249     brouard   202:   Revision 1.248  2016/09/07 14:10:18  brouard
                    203:   *** empty log message ***
                    204: 
1.248     brouard   205:   Revision 1.247  2016/09/02 11:11:21  brouard
                    206:   *** empty log message ***
                    207: 
1.247     brouard   208:   Revision 1.246  2016/09/02 08:49:22  brouard
                    209:   *** empty log message ***
                    210: 
1.246     brouard   211:   Revision 1.245  2016/09/02 07:25:01  brouard
                    212:   *** empty log message ***
                    213: 
1.245     brouard   214:   Revision 1.244  2016/09/02 07:17:34  brouard
                    215:   *** empty log message ***
                    216: 
1.244     brouard   217:   Revision 1.243  2016/09/02 06:45:35  brouard
                    218:   *** empty log message ***
                    219: 
1.243     brouard   220:   Revision 1.242  2016/08/30 15:01:20  brouard
                    221:   Summary: Fixing a lots
                    222: 
1.242     brouard   223:   Revision 1.241  2016/08/29 17:17:25  brouard
                    224:   Summary: gnuplot problem in Back projection to fix
                    225: 
1.241     brouard   226:   Revision 1.240  2016/08/29 07:53:18  brouard
                    227:   Summary: Better
                    228: 
1.240     brouard   229:   Revision 1.239  2016/08/26 15:51:03  brouard
                    230:   Summary: Improvement in Powell output in order to copy and paste
                    231: 
                    232:   Author:
                    233: 
1.239     brouard   234:   Revision 1.238  2016/08/26 14:23:35  brouard
                    235:   Summary: Starting tests of 0.99
                    236: 
1.238     brouard   237:   Revision 1.237  2016/08/26 09:20:19  brouard
                    238:   Summary: to valgrind
                    239: 
1.237     brouard   240:   Revision 1.236  2016/08/25 10:50:18  brouard
                    241:   *** empty log message ***
                    242: 
1.236     brouard   243:   Revision 1.235  2016/08/25 06:59:23  brouard
                    244:   *** empty log message ***
                    245: 
1.235     brouard   246:   Revision 1.234  2016/08/23 16:51:20  brouard
                    247:   *** empty log message ***
                    248: 
1.234     brouard   249:   Revision 1.233  2016/08/23 07:40:50  brouard
                    250:   Summary: not working
                    251: 
1.233     brouard   252:   Revision 1.232  2016/08/22 14:20:21  brouard
                    253:   Summary: not working
                    254: 
1.232     brouard   255:   Revision 1.231  2016/08/22 07:17:15  brouard
                    256:   Summary: not working
                    257: 
1.231     brouard   258:   Revision 1.230  2016/08/22 06:55:53  brouard
                    259:   Summary: Not working
                    260: 
1.230     brouard   261:   Revision 1.229  2016/07/23 09:45:53  brouard
                    262:   Summary: Completing for func too
                    263: 
1.229     brouard   264:   Revision 1.228  2016/07/22 17:45:30  brouard
                    265:   Summary: Fixing some arrays, still debugging
                    266: 
1.227     brouard   267:   Revision 1.226  2016/07/12 18:42:34  brouard
                    268:   Summary: temp
                    269: 
1.226     brouard   270:   Revision 1.225  2016/07/12 08:40:03  brouard
                    271:   Summary: saving but not running
                    272: 
1.225     brouard   273:   Revision 1.224  2016/07/01 13:16:01  brouard
                    274:   Summary: Fixes
                    275: 
1.224     brouard   276:   Revision 1.223  2016/02/19 09:23:35  brouard
                    277:   Summary: temporary
                    278: 
1.223     brouard   279:   Revision 1.222  2016/02/17 08:14:50  brouard
                    280:   Summary: Probably last 0.98 stable version 0.98r6
                    281: 
1.222     brouard   282:   Revision 1.221  2016/02/15 23:35:36  brouard
                    283:   Summary: minor bug
                    284: 
1.220     brouard   285:   Revision 1.219  2016/02/15 00:48:12  brouard
                    286:   *** empty log message ***
                    287: 
1.219     brouard   288:   Revision 1.218  2016/02/12 11:29:23  brouard
                    289:   Summary: 0.99 Back projections
                    290: 
1.218     brouard   291:   Revision 1.217  2015/12/23 17:18:31  brouard
                    292:   Summary: Experimental backcast
                    293: 
1.217     brouard   294:   Revision 1.216  2015/12/18 17:32:11  brouard
                    295:   Summary: 0.98r4 Warning and status=-2
                    296: 
                    297:   Version 0.98r4 is now:
                    298:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    299:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    300:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    301: 
1.216     brouard   302:   Revision 1.215  2015/12/16 08:52:24  brouard
                    303:   Summary: 0.98r4 working
                    304: 
1.215     brouard   305:   Revision 1.214  2015/12/16 06:57:54  brouard
                    306:   Summary: temporary not working
                    307: 
1.214     brouard   308:   Revision 1.213  2015/12/11 18:22:17  brouard
                    309:   Summary: 0.98r4
                    310: 
1.213     brouard   311:   Revision 1.212  2015/11/21 12:47:24  brouard
                    312:   Summary: minor typo
                    313: 
1.212     brouard   314:   Revision 1.211  2015/11/21 12:41:11  brouard
                    315:   Summary: 0.98r3 with some graph of projected cross-sectional
                    316: 
                    317:   Author: Nicolas Brouard
                    318: 
1.211     brouard   319:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   320:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   321:   Summary: Adding ftolpl parameter
                    322:   Author: N Brouard
                    323: 
                    324:   We had difficulties to get smoothed confidence intervals. It was due
                    325:   to the period prevalence which wasn't computed accurately. The inner
                    326:   parameter ftolpl is now an outer parameter of the .imach parameter
                    327:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    328:   computation are long.
                    329: 
1.209     brouard   330:   Revision 1.208  2015/11/17 14:31:57  brouard
                    331:   Summary: temporary
                    332: 
1.208     brouard   333:   Revision 1.207  2015/10/27 17:36:57  brouard
                    334:   *** empty log message ***
                    335: 
1.207     brouard   336:   Revision 1.206  2015/10/24 07:14:11  brouard
                    337:   *** empty log message ***
                    338: 
1.206     brouard   339:   Revision 1.205  2015/10/23 15:50:53  brouard
                    340:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    341: 
1.205     brouard   342:   Revision 1.204  2015/10/01 16:20:26  brouard
                    343:   Summary: Some new graphs of contribution to likelihood
                    344: 
1.204     brouard   345:   Revision 1.203  2015/09/30 17:45:14  brouard
                    346:   Summary: looking at better estimation of the hessian
                    347: 
                    348:   Also a better criteria for convergence to the period prevalence And
                    349:   therefore adding the number of years needed to converge. (The
                    350:   prevalence in any alive state shold sum to one
                    351: 
1.203     brouard   352:   Revision 1.202  2015/09/22 19:45:16  brouard
                    353:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    354: 
1.202     brouard   355:   Revision 1.201  2015/09/15 17:34:58  brouard
                    356:   Summary: 0.98r0
                    357: 
                    358:   - Some new graphs like suvival functions
                    359:   - Some bugs fixed like model=1+age+V2.
                    360: 
1.201     brouard   361:   Revision 1.200  2015/09/09 16:53:55  brouard
                    362:   Summary: Big bug thanks to Flavia
                    363: 
                    364:   Even model=1+age+V2. did not work anymore
                    365: 
1.200     brouard   366:   Revision 1.199  2015/09/07 14:09:23  brouard
                    367:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    368: 
1.199     brouard   369:   Revision 1.198  2015/09/03 07:14:39  brouard
                    370:   Summary: 0.98q5 Flavia
                    371: 
1.198     brouard   372:   Revision 1.197  2015/09/01 18:24:39  brouard
                    373:   *** empty log message ***
                    374: 
1.197     brouard   375:   Revision 1.196  2015/08/18 23:17:52  brouard
                    376:   Summary: 0.98q5
                    377: 
1.196     brouard   378:   Revision 1.195  2015/08/18 16:28:39  brouard
                    379:   Summary: Adding a hack for testing purpose
                    380: 
                    381:   After reading the title, ftol and model lines, if the comment line has
                    382:   a q, starting with #q, the answer at the end of the run is quit. It
                    383:   permits to run test files in batch with ctest. The former workaround was
                    384:   $ echo q | imach foo.imach
                    385: 
1.195     brouard   386:   Revision 1.194  2015/08/18 13:32:00  brouard
                    387:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    388: 
1.194     brouard   389:   Revision 1.193  2015/08/04 07:17:42  brouard
                    390:   Summary: 0.98q4
                    391: 
1.193     brouard   392:   Revision 1.192  2015/07/16 16:49:02  brouard
                    393:   Summary: Fixing some outputs
                    394: 
1.192     brouard   395:   Revision 1.191  2015/07/14 10:00:33  brouard
                    396:   Summary: Some fixes
                    397: 
1.191     brouard   398:   Revision 1.190  2015/05/05 08:51:13  brouard
                    399:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    400: 
                    401:   Fix 1+age+.
                    402: 
1.190     brouard   403:   Revision 1.189  2015/04/30 14:45:16  brouard
                    404:   Summary: 0.98q2
                    405: 
1.189     brouard   406:   Revision 1.188  2015/04/30 08:27:53  brouard
                    407:   *** empty log message ***
                    408: 
1.188     brouard   409:   Revision 1.187  2015/04/29 09:11:15  brouard
                    410:   *** empty log message ***
                    411: 
1.187     brouard   412:   Revision 1.186  2015/04/23 12:01:52  brouard
                    413:   Summary: V1*age is working now, version 0.98q1
                    414: 
                    415:   Some codes had been disabled in order to simplify and Vn*age was
                    416:   working in the optimization phase, ie, giving correct MLE parameters,
                    417:   but, as usual, outputs were not correct and program core dumped.
                    418: 
1.186     brouard   419:   Revision 1.185  2015/03/11 13:26:42  brouard
                    420:   Summary: Inclusion of compile and links command line for Intel Compiler
                    421: 
1.185     brouard   422:   Revision 1.184  2015/03/11 11:52:39  brouard
                    423:   Summary: Back from Windows 8. Intel Compiler
                    424: 
1.184     brouard   425:   Revision 1.183  2015/03/10 20:34:32  brouard
                    426:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    427: 
                    428:   We use directest instead of original Powell test; probably no
                    429:   incidence on the results, but better justifications;
                    430:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    431:   wrong results.
                    432: 
1.183     brouard   433:   Revision 1.182  2015/02/12 08:19:57  brouard
                    434:   Summary: Trying to keep directest which seems simpler and more general
                    435:   Author: Nicolas Brouard
                    436: 
1.182     brouard   437:   Revision 1.181  2015/02/11 23:22:24  brouard
                    438:   Summary: Comments on Powell added
                    439: 
                    440:   Author:
                    441: 
1.181     brouard   442:   Revision 1.180  2015/02/11 17:33:45  brouard
                    443:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    444: 
1.180     brouard   445:   Revision 1.179  2015/01/04 09:57:06  brouard
                    446:   Summary: back to OS/X
                    447: 
1.179     brouard   448:   Revision 1.178  2015/01/04 09:35:48  brouard
                    449:   *** empty log message ***
                    450: 
1.178     brouard   451:   Revision 1.177  2015/01/03 18:40:56  brouard
                    452:   Summary: Still testing ilc32 on OSX
                    453: 
1.177     brouard   454:   Revision 1.176  2015/01/03 16:45:04  brouard
                    455:   *** empty log message ***
                    456: 
1.176     brouard   457:   Revision 1.175  2015/01/03 16:33:42  brouard
                    458:   *** empty log message ***
                    459: 
1.175     brouard   460:   Revision 1.174  2015/01/03 16:15:49  brouard
                    461:   Summary: Still in cross-compilation
                    462: 
1.174     brouard   463:   Revision 1.173  2015/01/03 12:06:26  brouard
                    464:   Summary: trying to detect cross-compilation
                    465: 
1.173     brouard   466:   Revision 1.172  2014/12/27 12:07:47  brouard
                    467:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    468: 
1.172     brouard   469:   Revision 1.171  2014/12/23 13:26:59  brouard
                    470:   Summary: Back from Visual C
                    471: 
                    472:   Still problem with utsname.h on Windows
                    473: 
1.171     brouard   474:   Revision 1.170  2014/12/23 11:17:12  brouard
                    475:   Summary: Cleaning some \%% back to %%
                    476: 
                    477:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    478: 
1.170     brouard   479:   Revision 1.169  2014/12/22 23:08:31  brouard
                    480:   Summary: 0.98p
                    481: 
                    482:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    483: 
1.169     brouard   484:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   485:   Summary: update
1.169     brouard   486: 
1.168     brouard   487:   Revision 1.167  2014/12/22 13:50:56  brouard
                    488:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    489: 
                    490:   Testing on Linux 64
                    491: 
1.167     brouard   492:   Revision 1.166  2014/12/22 11:40:47  brouard
                    493:   *** empty log message ***
                    494: 
1.166     brouard   495:   Revision 1.165  2014/12/16 11:20:36  brouard
                    496:   Summary: After compiling on Visual C
                    497: 
                    498:   * imach.c (Module): Merging 1.61 to 1.162
                    499: 
1.165     brouard   500:   Revision 1.164  2014/12/16 10:52:11  brouard
                    501:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    502: 
                    503:   * imach.c (Module): Merging 1.61 to 1.162
                    504: 
1.164     brouard   505:   Revision 1.163  2014/12/16 10:30:11  brouard
                    506:   * imach.c (Module): Merging 1.61 to 1.162
                    507: 
1.163     brouard   508:   Revision 1.162  2014/09/25 11:43:39  brouard
                    509:   Summary: temporary backup 0.99!
                    510: 
1.162     brouard   511:   Revision 1.1  2014/09/16 11:06:58  brouard
                    512:   Summary: With some code (wrong) for nlopt
                    513: 
                    514:   Author:
                    515: 
                    516:   Revision 1.161  2014/09/15 20:41:41  brouard
                    517:   Summary: Problem with macro SQR on Intel compiler
                    518: 
1.161     brouard   519:   Revision 1.160  2014/09/02 09:24:05  brouard
                    520:   *** empty log message ***
                    521: 
1.160     brouard   522:   Revision 1.159  2014/09/01 10:34:10  brouard
                    523:   Summary: WIN32
                    524:   Author: Brouard
                    525: 
1.159     brouard   526:   Revision 1.158  2014/08/27 17:11:51  brouard
                    527:   *** empty log message ***
                    528: 
1.158     brouard   529:   Revision 1.157  2014/08/27 16:26:55  brouard
                    530:   Summary: Preparing windows Visual studio version
                    531:   Author: Brouard
                    532: 
                    533:   In order to compile on Visual studio, time.h is now correct and time_t
                    534:   and tm struct should be used. difftime should be used but sometimes I
                    535:   just make the differences in raw time format (time(&now).
                    536:   Trying to suppress #ifdef LINUX
                    537:   Add xdg-open for __linux in order to open default browser.
                    538: 
1.157     brouard   539:   Revision 1.156  2014/08/25 20:10:10  brouard
                    540:   *** empty log message ***
                    541: 
1.156     brouard   542:   Revision 1.155  2014/08/25 18:32:34  brouard
                    543:   Summary: New compile, minor changes
                    544:   Author: Brouard
                    545: 
1.155     brouard   546:   Revision 1.154  2014/06/20 17:32:08  brouard
                    547:   Summary: Outputs now all graphs of convergence to period prevalence
                    548: 
1.154     brouard   549:   Revision 1.153  2014/06/20 16:45:46  brouard
                    550:   Summary: If 3 live state, convergence to period prevalence on same graph
                    551:   Author: Brouard
                    552: 
1.153     brouard   553:   Revision 1.152  2014/06/18 17:54:09  brouard
                    554:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    555: 
1.152     brouard   556:   Revision 1.151  2014/06/18 16:43:30  brouard
                    557:   *** empty log message ***
                    558: 
1.151     brouard   559:   Revision 1.150  2014/06/18 16:42:35  brouard
                    560:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    561:   Author: brouard
                    562: 
1.150     brouard   563:   Revision 1.149  2014/06/18 15:51:14  brouard
                    564:   Summary: Some fixes in parameter files errors
                    565:   Author: Nicolas Brouard
                    566: 
1.149     brouard   567:   Revision 1.148  2014/06/17 17:38:48  brouard
                    568:   Summary: Nothing new
                    569:   Author: Brouard
                    570: 
                    571:   Just a new packaging for OS/X version 0.98nS
                    572: 
1.148     brouard   573:   Revision 1.147  2014/06/16 10:33:11  brouard
                    574:   *** empty log message ***
                    575: 
1.147     brouard   576:   Revision 1.146  2014/06/16 10:20:28  brouard
                    577:   Summary: Merge
                    578:   Author: Brouard
                    579: 
                    580:   Merge, before building revised version.
                    581: 
1.146     brouard   582:   Revision 1.145  2014/06/10 21:23:15  brouard
                    583:   Summary: Debugging with valgrind
                    584:   Author: Nicolas Brouard
                    585: 
                    586:   Lot of changes in order to output the results with some covariates
                    587:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    588:   improve the code.
                    589:   No more memory valgrind error but a lot has to be done in order to
                    590:   continue the work of splitting the code into subroutines.
                    591:   Also, decodemodel has been improved. Tricode is still not
                    592:   optimal. nbcode should be improved. Documentation has been added in
                    593:   the source code.
                    594: 
1.144     brouard   595:   Revision 1.143  2014/01/26 09:45:38  brouard
                    596:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    597: 
                    598:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    599:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    600: 
1.143     brouard   601:   Revision 1.142  2014/01/26 03:57:36  brouard
                    602:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    603: 
                    604:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    605: 
1.142     brouard   606:   Revision 1.141  2014/01/26 02:42:01  brouard
                    607:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    608: 
1.141     brouard   609:   Revision 1.140  2011/09/02 10:37:54  brouard
                    610:   Summary: times.h is ok with mingw32 now.
                    611: 
1.140     brouard   612:   Revision 1.139  2010/06/14 07:50:17  brouard
                    613:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    614:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    615: 
1.139     brouard   616:   Revision 1.138  2010/04/30 18:19:40  brouard
                    617:   *** empty log message ***
                    618: 
1.138     brouard   619:   Revision 1.137  2010/04/29 18:11:38  brouard
                    620:   (Module): Checking covariates for more complex models
                    621:   than V1+V2. A lot of change to be done. Unstable.
                    622: 
1.137     brouard   623:   Revision 1.136  2010/04/26 20:30:53  brouard
                    624:   (Module): merging some libgsl code. Fixing computation
                    625:   of likelione (using inter/intrapolation if mle = 0) in order to
                    626:   get same likelihood as if mle=1.
                    627:   Some cleaning of code and comments added.
                    628: 
1.136     brouard   629:   Revision 1.135  2009/10/29 15:33:14  brouard
                    630:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    631: 
1.135     brouard   632:   Revision 1.134  2009/10/29 13:18:53  brouard
                    633:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    634: 
1.134     brouard   635:   Revision 1.133  2009/07/06 10:21:25  brouard
                    636:   just nforces
                    637: 
1.133     brouard   638:   Revision 1.132  2009/07/06 08:22:05  brouard
                    639:   Many tings
                    640: 
1.132     brouard   641:   Revision 1.131  2009/06/20 16:22:47  brouard
                    642:   Some dimensions resccaled
                    643: 
1.131     brouard   644:   Revision 1.130  2009/05/26 06:44:34  brouard
                    645:   (Module): Max Covariate is now set to 20 instead of 8. A
                    646:   lot of cleaning with variables initialized to 0. Trying to make
                    647:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    648: 
1.130     brouard   649:   Revision 1.129  2007/08/31 13:49:27  lievre
                    650:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    651: 
1.129     lievre    652:   Revision 1.128  2006/06/30 13:02:05  brouard
                    653:   (Module): Clarifications on computing e.j
                    654: 
1.128     brouard   655:   Revision 1.127  2006/04/28 18:11:50  brouard
                    656:   (Module): Yes the sum of survivors was wrong since
                    657:   imach-114 because nhstepm was no more computed in the age
                    658:   loop. Now we define nhstepma in the age loop.
                    659:   (Module): In order to speed up (in case of numerous covariates) we
                    660:   compute health expectancies (without variances) in a first step
                    661:   and then all the health expectancies with variances or standard
                    662:   deviation (needs data from the Hessian matrices) which slows the
                    663:   computation.
                    664:   In the future we should be able to stop the program is only health
                    665:   expectancies and graph are needed without standard deviations.
                    666: 
1.127     brouard   667:   Revision 1.126  2006/04/28 17:23:28  brouard
                    668:   (Module): Yes the sum of survivors was wrong since
                    669:   imach-114 because nhstepm was no more computed in the age
                    670:   loop. Now we define nhstepma in the age loop.
                    671:   Version 0.98h
                    672: 
1.126     brouard   673:   Revision 1.125  2006/04/04 15:20:31  lievre
                    674:   Errors in calculation of health expectancies. Age was not initialized.
                    675:   Forecasting file added.
                    676: 
                    677:   Revision 1.124  2006/03/22 17:13:53  lievre
                    678:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    679:   The log-likelihood is printed in the log file
                    680: 
                    681:   Revision 1.123  2006/03/20 10:52:43  brouard
                    682:   * imach.c (Module): <title> changed, corresponds to .htm file
                    683:   name. <head> headers where missing.
                    684: 
                    685:   * imach.c (Module): Weights can have a decimal point as for
                    686:   English (a comma might work with a correct LC_NUMERIC environment,
                    687:   otherwise the weight is truncated).
                    688:   Modification of warning when the covariates values are not 0 or
                    689:   1.
                    690:   Version 0.98g
                    691: 
                    692:   Revision 1.122  2006/03/20 09:45:41  brouard
                    693:   (Module): Weights can have a decimal point as for
                    694:   English (a comma might work with a correct LC_NUMERIC environment,
                    695:   otherwise the weight is truncated).
                    696:   Modification of warning when the covariates values are not 0 or
                    697:   1.
                    698:   Version 0.98g
                    699: 
                    700:   Revision 1.121  2006/03/16 17:45:01  lievre
                    701:   * imach.c (Module): Comments concerning covariates added
                    702: 
                    703:   * imach.c (Module): refinements in the computation of lli if
                    704:   status=-2 in order to have more reliable computation if stepm is
                    705:   not 1 month. Version 0.98f
                    706: 
                    707:   Revision 1.120  2006/03/16 15:10:38  lievre
                    708:   (Module): refinements in the computation of lli if
                    709:   status=-2 in order to have more reliable computation if stepm is
                    710:   not 1 month. Version 0.98f
                    711: 
                    712:   Revision 1.119  2006/03/15 17:42:26  brouard
                    713:   (Module): Bug if status = -2, the loglikelihood was
                    714:   computed as likelihood omitting the logarithm. Version O.98e
                    715: 
                    716:   Revision 1.118  2006/03/14 18:20:07  brouard
                    717:   (Module): varevsij Comments added explaining the second
                    718:   table of variances if popbased=1 .
                    719:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    720:   (Module): Function pstamp added
                    721:   (Module): Version 0.98d
                    722: 
                    723:   Revision 1.117  2006/03/14 17:16:22  brouard
                    724:   (Module): varevsij Comments added explaining the second
                    725:   table of variances if popbased=1 .
                    726:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    727:   (Module): Function pstamp added
                    728:   (Module): Version 0.98d
                    729: 
                    730:   Revision 1.116  2006/03/06 10:29:27  brouard
                    731:   (Module): Variance-covariance wrong links and
                    732:   varian-covariance of ej. is needed (Saito).
                    733: 
                    734:   Revision 1.115  2006/02/27 12:17:45  brouard
                    735:   (Module): One freematrix added in mlikeli! 0.98c
                    736: 
                    737:   Revision 1.114  2006/02/26 12:57:58  brouard
                    738:   (Module): Some improvements in processing parameter
                    739:   filename with strsep.
                    740: 
                    741:   Revision 1.113  2006/02/24 14:20:24  brouard
                    742:   (Module): Memory leaks checks with valgrind and:
                    743:   datafile was not closed, some imatrix were not freed and on matrix
                    744:   allocation too.
                    745: 
                    746:   Revision 1.112  2006/01/30 09:55:26  brouard
                    747:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    748: 
                    749:   Revision 1.111  2006/01/25 20:38:18  brouard
                    750:   (Module): Lots of cleaning and bugs added (Gompertz)
                    751:   (Module): Comments can be added in data file. Missing date values
                    752:   can be a simple dot '.'.
                    753: 
                    754:   Revision 1.110  2006/01/25 00:51:50  brouard
                    755:   (Module): Lots of cleaning and bugs added (Gompertz)
                    756: 
                    757:   Revision 1.109  2006/01/24 19:37:15  brouard
                    758:   (Module): Comments (lines starting with a #) are allowed in data.
                    759: 
                    760:   Revision 1.108  2006/01/19 18:05:42  lievre
                    761:   Gnuplot problem appeared...
                    762:   To be fixed
                    763: 
                    764:   Revision 1.107  2006/01/19 16:20:37  brouard
                    765:   Test existence of gnuplot in imach path
                    766: 
                    767:   Revision 1.106  2006/01/19 13:24:36  brouard
                    768:   Some cleaning and links added in html output
                    769: 
                    770:   Revision 1.105  2006/01/05 20:23:19  lievre
                    771:   *** empty log message ***
                    772: 
                    773:   Revision 1.104  2005/09/30 16:11:43  lievre
                    774:   (Module): sump fixed, loop imx fixed, and simplifications.
                    775:   (Module): If the status is missing at the last wave but we know
                    776:   that the person is alive, then we can code his/her status as -2
                    777:   (instead of missing=-1 in earlier versions) and his/her
                    778:   contributions to the likelihood is 1 - Prob of dying from last
                    779:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    780:   the healthy state at last known wave). Version is 0.98
                    781: 
                    782:   Revision 1.103  2005/09/30 15:54:49  lievre
                    783:   (Module): sump fixed, loop imx fixed, and simplifications.
                    784: 
                    785:   Revision 1.102  2004/09/15 17:31:30  brouard
                    786:   Add the possibility to read data file including tab characters.
                    787: 
                    788:   Revision 1.101  2004/09/15 10:38:38  brouard
                    789:   Fix on curr_time
                    790: 
                    791:   Revision 1.100  2004/07/12 18:29:06  brouard
                    792:   Add version for Mac OS X. Just define UNIX in Makefile
                    793: 
                    794:   Revision 1.99  2004/06/05 08:57:40  brouard
                    795:   *** empty log message ***
                    796: 
                    797:   Revision 1.98  2004/05/16 15:05:56  brouard
                    798:   New version 0.97 . First attempt to estimate force of mortality
                    799:   directly from the data i.e. without the need of knowing the health
                    800:   state at each age, but using a Gompertz model: log u =a + b*age .
                    801:   This is the basic analysis of mortality and should be done before any
                    802:   other analysis, in order to test if the mortality estimated from the
                    803:   cross-longitudinal survey is different from the mortality estimated
                    804:   from other sources like vital statistic data.
                    805: 
                    806:   The same imach parameter file can be used but the option for mle should be -3.
                    807: 
1.133     brouard   808:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   809:   former routines in order to include the new code within the former code.
                    810: 
                    811:   The output is very simple: only an estimate of the intercept and of
                    812:   the slope with 95% confident intervals.
                    813: 
                    814:   Current limitations:
                    815:   A) Even if you enter covariates, i.e. with the
                    816:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    817:   B) There is no computation of Life Expectancy nor Life Table.
                    818: 
                    819:   Revision 1.97  2004/02/20 13:25:42  lievre
                    820:   Version 0.96d. Population forecasting command line is (temporarily)
                    821:   suppressed.
                    822: 
                    823:   Revision 1.96  2003/07/15 15:38:55  brouard
                    824:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    825:   rewritten within the same printf. Workaround: many printfs.
                    826: 
                    827:   Revision 1.95  2003/07/08 07:54:34  brouard
                    828:   * imach.c (Repository):
                    829:   (Repository): Using imachwizard code to output a more meaningful covariance
                    830:   matrix (cov(a12,c31) instead of numbers.
                    831: 
                    832:   Revision 1.94  2003/06/27 13:00:02  brouard
                    833:   Just cleaning
                    834: 
                    835:   Revision 1.93  2003/06/25 16:33:55  brouard
                    836:   (Module): On windows (cygwin) function asctime_r doesn't
                    837:   exist so I changed back to asctime which exists.
                    838:   (Module): Version 0.96b
                    839: 
                    840:   Revision 1.92  2003/06/25 16:30:45  brouard
                    841:   (Module): On windows (cygwin) function asctime_r doesn't
                    842:   exist so I changed back to asctime which exists.
                    843: 
                    844:   Revision 1.91  2003/06/25 15:30:29  brouard
                    845:   * imach.c (Repository): Duplicated warning errors corrected.
                    846:   (Repository): Elapsed time after each iteration is now output. It
                    847:   helps to forecast when convergence will be reached. Elapsed time
                    848:   is stamped in powell.  We created a new html file for the graphs
                    849:   concerning matrix of covariance. It has extension -cov.htm.
                    850: 
                    851:   Revision 1.90  2003/06/24 12:34:15  brouard
                    852:   (Module): Some bugs corrected for windows. Also, when
                    853:   mle=-1 a template is output in file "or"mypar.txt with the design
                    854:   of the covariance matrix to be input.
                    855: 
                    856:   Revision 1.89  2003/06/24 12:30:52  brouard
                    857:   (Module): Some bugs corrected for windows. Also, when
                    858:   mle=-1 a template is output in file "or"mypar.txt with the design
                    859:   of the covariance matrix to be input.
                    860: 
                    861:   Revision 1.88  2003/06/23 17:54:56  brouard
                    862:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    863: 
                    864:   Revision 1.87  2003/06/18 12:26:01  brouard
                    865:   Version 0.96
                    866: 
                    867:   Revision 1.86  2003/06/17 20:04:08  brouard
                    868:   (Module): Change position of html and gnuplot routines and added
                    869:   routine fileappend.
                    870: 
                    871:   Revision 1.85  2003/06/17 13:12:43  brouard
                    872:   * imach.c (Repository): Check when date of death was earlier that
                    873:   current date of interview. It may happen when the death was just
                    874:   prior to the death. In this case, dh was negative and likelihood
                    875:   was wrong (infinity). We still send an "Error" but patch by
                    876:   assuming that the date of death was just one stepm after the
                    877:   interview.
                    878:   (Repository): Because some people have very long ID (first column)
                    879:   we changed int to long in num[] and we added a new lvector for
                    880:   memory allocation. But we also truncated to 8 characters (left
                    881:   truncation)
                    882:   (Repository): No more line truncation errors.
                    883: 
                    884:   Revision 1.84  2003/06/13 21:44:43  brouard
                    885:   * imach.c (Repository): Replace "freqsummary" at a correct
                    886:   place. It differs from routine "prevalence" which may be called
                    887:   many times. Probs is memory consuming and must be used with
                    888:   parcimony.
                    889:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    890: 
                    891:   Revision 1.83  2003/06/10 13:39:11  lievre
                    892:   *** empty log message ***
                    893: 
                    894:   Revision 1.82  2003/06/05 15:57:20  brouard
                    895:   Add log in  imach.c and  fullversion number is now printed.
                    896: 
                    897: */
                    898: /*
                    899:    Interpolated Markov Chain
                    900: 
                    901:   Short summary of the programme:
                    902:   
1.227     brouard   903:   This program computes Healthy Life Expectancies or State-specific
                    904:   (if states aren't health statuses) Expectancies from
                    905:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    906: 
                    907:   -1- a first survey ("cross") where individuals from different ages
                    908:   are interviewed on their health status or degree of disability (in
                    909:   the case of a health survey which is our main interest)
                    910: 
                    911:   -2- at least a second wave of interviews ("longitudinal") which
                    912:   measure each change (if any) in individual health status.  Health
                    913:   expectancies are computed from the time spent in each health state
                    914:   according to a model. More health states you consider, more time is
                    915:   necessary to reach the Maximum Likelihood of the parameters involved
                    916:   in the model.  The simplest model is the multinomial logistic model
                    917:   where pij is the probability to be observed in state j at the second
                    918:   wave conditional to be observed in state i at the first
                    919:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    920:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    921:   have a more complex model than "constant and age", you should modify
                    922:   the program where the markup *Covariates have to be included here
                    923:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   924:   convergence.
                    925: 
                    926:   The advantage of this computer programme, compared to a simple
                    927:   multinomial logistic model, is clear when the delay between waves is not
                    928:   identical for each individual. Also, if a individual missed an
                    929:   intermediate interview, the information is lost, but taken into
                    930:   account using an interpolation or extrapolation.  
                    931: 
                    932:   hPijx is the probability to be observed in state i at age x+h
                    933:   conditional to the observed state i at age x. The delay 'h' can be
                    934:   split into an exact number (nh*stepm) of unobserved intermediate
                    935:   states. This elementary transition (by month, quarter,
                    936:   semester or year) is modelled as a multinomial logistic.  The hPx
                    937:   matrix is simply the matrix product of nh*stepm elementary matrices
                    938:   and the contribution of each individual to the likelihood is simply
                    939:   hPijx.
                    940: 
                    941:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   942:   of the life expectancies. It also computes the period (stable) prevalence.
                    943: 
                    944: Back prevalence and projections:
1.227     brouard   945: 
                    946:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    947:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    948:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    949:    mobilavproj)
                    950: 
                    951:     Computes the back prevalence limit for any combination of
                    952:     covariate values k at any age between ageminpar and agemaxpar and
                    953:     returns it in **bprlim. In the loops,
                    954: 
                    955:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    956:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    957: 
                    958:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   959:    Computes for any combination of covariates k and any age between bage and fage 
                    960:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    961:                        oldm=oldms;savm=savms;
1.227     brouard   962: 
1.267     brouard   963:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   964:      Computes the transition matrix starting at age 'age' over
                    965:      'nhstepm*hstepm*stepm' months (i.e. until
                    966:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   967:      nhstepm*hstepm matrices. 
                    968: 
                    969:      Returns p3mat[i][j][h] after calling
                    970:      p3mat[i][j][h]=matprod2(newm,
                    971:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    972:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    973:      oldm);
1.226     brouard   974: 
                    975: Important routines
                    976: 
                    977: - func (or funcone), computes logit (pij) distinguishing
                    978:   o fixed variables (single or product dummies or quantitative);
                    979:   o varying variables by:
                    980:    (1) wave (single, product dummies, quantitative), 
                    981:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    982:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    983:        % varying dummy (not done) or quantitative (not done);
                    984: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                    985:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                    986: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                    987:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                    988:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard   989: 
1.226     brouard   990: 
                    991:   
1.133     brouard   992:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                    993:            Institut national d'études démographiques, Paris.
1.126     brouard   994:   This software have been partly granted by Euro-REVES, a concerted action
                    995:   from the European Union.
                    996:   It is copyrighted identically to a GNU software product, ie programme and
                    997:   software can be distributed freely for non commercial use. Latest version
                    998:   can be accessed at http://euroreves.ined.fr/imach .
                    999: 
                   1000:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                   1001:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                   1002:   
                   1003:   **********************************************************************/
                   1004: /*
                   1005:   main
                   1006:   read parameterfile
                   1007:   read datafile
                   1008:   concatwav
                   1009:   freqsummary
                   1010:   if (mle >= 1)
                   1011:     mlikeli
                   1012:   print results files
                   1013:   if mle==1 
                   1014:      computes hessian
                   1015:   read end of parameter file: agemin, agemax, bage, fage, estepm
                   1016:       begin-prev-date,...
                   1017:   open gnuplot file
                   1018:   open html file
1.145     brouard  1019:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                   1020:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                   1021:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                   1022:     freexexit2 possible for memory heap.
                   1023: 
                   1024:   h Pij x                         | pij_nom  ficrestpij
                   1025:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                   1026:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                   1027:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                   1028: 
                   1029:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                   1030:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                   1031:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                   1032:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                   1033:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                   1034: 
1.126     brouard  1035:   forecasting if prevfcast==1 prevforecast call prevalence()
                   1036:   health expectancies
                   1037:   Variance-covariance of DFLE
                   1038:   prevalence()
                   1039:    movingaverage()
                   1040:   varevsij() 
                   1041:   if popbased==1 varevsij(,popbased)
                   1042:   total life expectancies
                   1043:   Variance of period (stable) prevalence
                   1044:  end
                   1045: */
                   1046: 
1.187     brouard  1047: /* #define DEBUG */
                   1048: /* #define DEBUGBRENT */
1.203     brouard  1049: /* #define DEBUGLINMIN */
                   1050: /* #define DEBUGHESS */
                   1051: #define DEBUGHESSIJ
1.224     brouard  1052: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard  1053: #define POWELL /* Instead of NLOPT */
1.224     brouard  1054: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard  1055: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                   1056: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard  1057: 
                   1058: #include <math.h>
                   1059: #include <stdio.h>
                   1060: #include <stdlib.h>
                   1061: #include <string.h>
1.226     brouard  1062: #include <ctype.h>
1.159     brouard  1063: 
                   1064: #ifdef _WIN32
                   1065: #include <io.h>
1.172     brouard  1066: #include <windows.h>
                   1067: #include <tchar.h>
1.159     brouard  1068: #else
1.126     brouard  1069: #include <unistd.h>
1.159     brouard  1070: #endif
1.126     brouard  1071: 
                   1072: #include <limits.h>
                   1073: #include <sys/types.h>
1.171     brouard  1074: 
                   1075: #if defined(__GNUC__)
                   1076: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1077: #endif
                   1078: 
1.126     brouard  1079: #include <sys/stat.h>
                   1080: #include <errno.h>
1.159     brouard  1081: /* extern int errno; */
1.126     brouard  1082: 
1.157     brouard  1083: /* #ifdef LINUX */
                   1084: /* #include <time.h> */
                   1085: /* #include "timeval.h" */
                   1086: /* #else */
                   1087: /* #include <sys/time.h> */
                   1088: /* #endif */
                   1089: 
1.126     brouard  1090: #include <time.h>
                   1091: 
1.136     brouard  1092: #ifdef GSL
                   1093: #include <gsl/gsl_errno.h>
                   1094: #include <gsl/gsl_multimin.h>
                   1095: #endif
                   1096: 
1.167     brouard  1097: 
1.162     brouard  1098: #ifdef NLOPT
                   1099: #include <nlopt.h>
                   1100: typedef struct {
                   1101:   double (* function)(double [] );
                   1102: } myfunc_data ;
                   1103: #endif
                   1104: 
1.126     brouard  1105: /* #include <libintl.h> */
                   1106: /* #define _(String) gettext (String) */
                   1107: 
1.251     brouard  1108: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1109: 
                   1110: #define GNUPLOTPROGRAM "gnuplot"
                   1111: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1112: #define FILENAMELENGTH 132
                   1113: 
                   1114: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1115: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1116: 
1.144     brouard  1117: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1118: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1119: 
                   1120: #define NINTERVMAX 8
1.144     brouard  1121: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1122: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.291     brouard  1123: #define NCOVMAX 20  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1124: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1125: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1126: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1127: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1128: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1129: /* #define AGESUP 130 */
1.288     brouard  1130: /* #define AGESUP 150 */
                   1131: #define AGESUP 200
1.268     brouard  1132: #define AGEINF 0
1.218     brouard  1133: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1134: #define AGEBASE 40
1.194     brouard  1135: #define AGEOVERFLOW 1.e20
1.164     brouard  1136: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1137: #ifdef _WIN32
                   1138: #define DIRSEPARATOR '\\'
                   1139: #define CHARSEPARATOR "\\"
                   1140: #define ODIRSEPARATOR '/'
                   1141: #else
1.126     brouard  1142: #define DIRSEPARATOR '/'
                   1143: #define CHARSEPARATOR "/"
                   1144: #define ODIRSEPARATOR '\\'
                   1145: #endif
                   1146: 
1.308   ! brouard  1147: /* $Id: imach.c,v 1.307 2021/03/08 18:11:32 brouard Exp $ */
1.126     brouard  1148: /* $State: Exp $ */
1.196     brouard  1149: #include "version.h"
                   1150: char version[]=__IMACH_VERSION__;
1.308   ! brouard  1151: char copyright[]="March 2021,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2020, Nihon University 2021, INED 2000-2021";
        !          1152: char fullversion[]="$Revision: 1.307 $ $Date: 2021/03/08 18:11:32 $"; 
1.126     brouard  1153: char strstart[80];
                   1154: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1155: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1156: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1157: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1158: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1159: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1160: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1161: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1162: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1163: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1164: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1165: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1166: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1167: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1168: int nsd=0; /**< Total number of single dummy variables (output) */
                   1169: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1170: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1171: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1172: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1173: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1174: int cptcov=0; /* Working variable */
1.290     brouard  1175: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1176: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.302     brouard  1177: int npar=NPARMAX; /* Number of parameters (nlstate+ndeath-1)*nlstate*ncovmodel; */
1.126     brouard  1178: int nlstate=2; /* Number of live states */
                   1179: int ndeath=1; /* Number of dead states */
1.130     brouard  1180: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1181: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1182: int popbased=0;
                   1183: 
                   1184: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1185: int maxwav=0; /* Maxim number of waves */
                   1186: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1187: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1188: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1189:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1190: int mle=1, weightopt=0;
1.126     brouard  1191: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1192: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1193: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1194:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1195: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1196: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1197: 
1.130     brouard  1198: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1199: double **matprod2(); /* test */
1.126     brouard  1200: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1201: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1202: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1203: 
1.136     brouard  1204: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1205: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1206: FILE *ficlog, *ficrespow;
1.130     brouard  1207: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1208: double fretone; /* Only one call to likelihood */
1.130     brouard  1209: long ipmx=0; /* Number of contributions */
1.126     brouard  1210: double sw; /* Sum of weights */
                   1211: char filerespow[FILENAMELENGTH];
                   1212: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1213: FILE *ficresilk;
                   1214: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1215: FILE *ficresprobmorprev;
                   1216: FILE *fichtm, *fichtmcov; /* Html File */
                   1217: FILE *ficreseij;
                   1218: char filerese[FILENAMELENGTH];
                   1219: FILE *ficresstdeij;
                   1220: char fileresstde[FILENAMELENGTH];
                   1221: FILE *ficrescveij;
                   1222: char filerescve[FILENAMELENGTH];
                   1223: FILE  *ficresvij;
                   1224: char fileresv[FILENAMELENGTH];
1.269     brouard  1225: 
1.126     brouard  1226: char title[MAXLINE];
1.234     brouard  1227: char model[MAXLINE]; /**< The model line */
1.217     brouard  1228: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1229: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1230: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1231: char command[FILENAMELENGTH];
                   1232: int  outcmd=0;
                   1233: 
1.217     brouard  1234: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1235: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1236: char filelog[FILENAMELENGTH]; /* Log file */
                   1237: char filerest[FILENAMELENGTH];
                   1238: char fileregp[FILENAMELENGTH];
                   1239: char popfile[FILENAMELENGTH];
                   1240: 
                   1241: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1242: 
1.157     brouard  1243: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1244: /* struct timezone tzp; */
                   1245: /* extern int gettimeofday(); */
                   1246: struct tm tml, *gmtime(), *localtime();
                   1247: 
                   1248: extern time_t time();
                   1249: 
                   1250: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1251: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1252: struct tm tm;
                   1253: 
1.126     brouard  1254: char strcurr[80], strfor[80];
                   1255: 
                   1256: char *endptr;
                   1257: long lval;
                   1258: double dval;
                   1259: 
                   1260: #define NR_END 1
                   1261: #define FREE_ARG char*
                   1262: #define FTOL 1.0e-10
                   1263: 
                   1264: #define NRANSI 
1.240     brouard  1265: #define ITMAX 200
                   1266: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1267: 
                   1268: #define TOL 2.0e-4 
                   1269: 
                   1270: #define CGOLD 0.3819660 
                   1271: #define ZEPS 1.0e-10 
                   1272: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1273: 
                   1274: #define GOLD 1.618034 
                   1275: #define GLIMIT 100.0 
                   1276: #define TINY 1.0e-20 
                   1277: 
                   1278: static double maxarg1,maxarg2;
                   1279: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1280: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1281:   
                   1282: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1283: #define rint(a) floor(a+0.5)
1.166     brouard  1284: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1285: #define mytinydouble 1.0e-16
1.166     brouard  1286: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1287: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1288: /* static double dsqrarg; */
                   1289: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1290: static double sqrarg;
                   1291: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1292: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1293: int agegomp= AGEGOMP;
                   1294: 
                   1295: int imx; 
                   1296: int stepm=1;
                   1297: /* Stepm, step in month: minimum step interpolation*/
                   1298: 
                   1299: int estepm;
                   1300: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1301: 
                   1302: int m,nb;
                   1303: long *num;
1.197     brouard  1304: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1305: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1306:                   covariate for which somebody answered excluding 
                   1307:                   undefined. Usually 2: 0 and 1. */
                   1308: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1309:                             covariate for which somebody answered including 
                   1310:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1311: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1312: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1313: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1314: double *ageexmed,*agecens;
                   1315: double dateintmean=0;
1.296     brouard  1316:   double anprojd, mprojd, jprojd; /* For eventual projections */
                   1317:   double anprojf, mprojf, jprojf;
1.126     brouard  1318: 
1.296     brouard  1319:   double anbackd, mbackd, jbackd; /* For eventual backprojections */
                   1320:   double anbackf, mbackf, jbackf;
                   1321:   double jintmean,mintmean,aintmean;  
1.126     brouard  1322: double *weight;
                   1323: int **s; /* Status */
1.141     brouard  1324: double *agedc;
1.145     brouard  1325: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1326:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1327:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1328: double **coqvar; /* Fixed quantitative covariate nqv */
                   1329: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1330: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1331: double  idx; 
                   1332: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1333: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1334: /*k          1  2   3   4     5    6    7     8    9 */
                   1335: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1336: /* Tndvar[k]    1   2   3               4          5 */
                   1337: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1338: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1339: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1340: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1341: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1342: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1343: /* Tprod[i]=k           4               7            */
                   1344: /* Tage[i]=k                  5               8      */
                   1345: /* */
                   1346: /* Type                    */
                   1347: /* V         1  2  3  4  5 */
                   1348: /*           F  F  V  V  V */
                   1349: /*           D  Q  D  D  Q */
                   1350: /*                         */
                   1351: int *TvarsD;
                   1352: int *TvarsDind;
                   1353: int *TvarsQ;
                   1354: int *TvarsQind;
                   1355: 
1.235     brouard  1356: #define MAXRESULTLINES 10
                   1357: int nresult=0;
1.258     brouard  1358: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1359: int TKresult[MAXRESULTLINES];
1.237     brouard  1360: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1361: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1362: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1363: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1364: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1365: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1366: 
1.234     brouard  1367: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1368: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1369: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1370: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1371: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1372: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1373: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1374: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1375: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1376: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1377: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1378: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1379: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1380: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1381: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1382: 
1.230     brouard  1383: int *Tvarsel; /**< Selected covariates for output */
                   1384: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1385: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1386: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1387: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1388: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1389: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1390: int *Tage;
1.227     brouard  1391: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1392: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1393: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1394: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1395: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1396: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1397: int **Tvard;
                   1398: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1399: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1400: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1401:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1402:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1403: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1404: double *lsurv, *lpop, *tpop;
                   1405: 
1.231     brouard  1406: #define FD 1; /* Fixed dummy covariate */
                   1407: #define FQ 2; /* Fixed quantitative covariate */
                   1408: #define FP 3; /* Fixed product covariate */
                   1409: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1410: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1411: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1412: #define VD 10; /* Varying dummy covariate */
                   1413: #define VQ 11; /* Varying quantitative covariate */
                   1414: #define VP 12; /* Varying product covariate */
                   1415: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1416: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1417: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1418: #define APFD 16; /* Age product * fixed dummy covariate */
                   1419: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1420: #define APVD 18; /* Age product * varying dummy covariate */
                   1421: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1422: 
                   1423: #define FTYPE 1; /* Fixed covariate */
                   1424: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1425: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1426: 
                   1427: struct kmodel{
                   1428:        int maintype; /* main type */
                   1429:        int subtype; /* subtype */
                   1430: };
                   1431: struct kmodel modell[NCOVMAX];
                   1432: 
1.143     brouard  1433: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1434: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1435: 
                   1436: /**************** split *************************/
                   1437: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1438: {
                   1439:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1440:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1441:   */ 
                   1442:   char *ss;                            /* pointer */
1.186     brouard  1443:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1444: 
                   1445:   l1 = strlen(path );                  /* length of path */
                   1446:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1447:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1448:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1449:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1450:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1451:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1452:     /* get current working directory */
                   1453:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1454: #ifdef WIN32
                   1455:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1456: #else
                   1457:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1458: #endif
1.126     brouard  1459:       return( GLOCK_ERROR_GETCWD );
                   1460:     }
                   1461:     /* got dirc from getcwd*/
                   1462:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1463:   } else {                             /* strip directory from path */
1.126     brouard  1464:     ss++;                              /* after this, the filename */
                   1465:     l2 = strlen( ss );                 /* length of filename */
                   1466:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1467:     strcpy( name, ss );                /* save file name */
                   1468:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1469:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1470:     printf(" DIRC2 = %s \n",dirc);
                   1471:   }
                   1472:   /* We add a separator at the end of dirc if not exists */
                   1473:   l1 = strlen( dirc );                 /* length of directory */
                   1474:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1475:     dirc[l1] =  DIRSEPARATOR;
                   1476:     dirc[l1+1] = 0; 
                   1477:     printf(" DIRC3 = %s \n",dirc);
                   1478:   }
                   1479:   ss = strrchr( name, '.' );           /* find last / */
                   1480:   if (ss >0){
                   1481:     ss++;
                   1482:     strcpy(ext,ss);                    /* save extension */
                   1483:     l1= strlen( name);
                   1484:     l2= strlen(ss)+1;
                   1485:     strncpy( finame, name, l1-l2);
                   1486:     finame[l1-l2]= 0;
                   1487:   }
                   1488: 
                   1489:   return( 0 );                         /* we're done */
                   1490: }
                   1491: 
                   1492: 
                   1493: /******************************************/
                   1494: 
                   1495: void replace_back_to_slash(char *s, char*t)
                   1496: {
                   1497:   int i;
                   1498:   int lg=0;
                   1499:   i=0;
                   1500:   lg=strlen(t);
                   1501:   for(i=0; i<= lg; i++) {
                   1502:     (s[i] = t[i]);
                   1503:     if (t[i]== '\\') s[i]='/';
                   1504:   }
                   1505: }
                   1506: 
1.132     brouard  1507: char *trimbb(char *out, char *in)
1.137     brouard  1508: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1509:   char *s;
                   1510:   s=out;
                   1511:   while (*in != '\0'){
1.137     brouard  1512:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1513:       in++;
                   1514:     }
                   1515:     *out++ = *in++;
                   1516:   }
                   1517:   *out='\0';
                   1518:   return s;
                   1519: }
                   1520: 
1.187     brouard  1521: /* char *substrchaine(char *out, char *in, char *chain) */
                   1522: /* { */
                   1523: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1524: /*   char *s, *t; */
                   1525: /*   t=in;s=out; */
                   1526: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1527: /*     *out++ = *in++; */
                   1528: /*   } */
                   1529: 
                   1530: /*   /\* *in matches *chain *\/ */
                   1531: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1532: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1533: /*   } */
                   1534: /*   in--; chain--; */
                   1535: /*   while ( (*in != '\0')){ */
                   1536: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1537: /*     *out++ = *in++; */
                   1538: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1539: /*   } */
                   1540: /*   *out='\0'; */
                   1541: /*   out=s; */
                   1542: /*   return out; */
                   1543: /* } */
                   1544: char *substrchaine(char *out, char *in, char *chain)
                   1545: {
                   1546:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1547:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1548: 
                   1549:   char *strloc;
                   1550: 
                   1551:   strcpy (out, in); 
                   1552:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1553:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1554:   if(strloc != NULL){ 
                   1555:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1556:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1557:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1558:   }
                   1559:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1560:   return out;
                   1561: }
                   1562: 
                   1563: 
1.145     brouard  1564: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1565: {
1.187     brouard  1566:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1567:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.187     brouard  1568:      gives blocc="abcdef" and alocc="ghi2j".
1.145     brouard  1569:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1570:   */
1.160     brouard  1571:   char *s, *t;
1.145     brouard  1572:   t=in;s=in;
                   1573:   while ((*in != occ) && (*in != '\0')){
                   1574:     *alocc++ = *in++;
                   1575:   }
                   1576:   if( *in == occ){
                   1577:     *(alocc)='\0';
                   1578:     s=++in;
                   1579:   }
                   1580:  
                   1581:   if (s == t) {/* occ not found */
                   1582:     *(alocc-(in-s))='\0';
                   1583:     in=s;
                   1584:   }
                   1585:   while ( *in != '\0'){
                   1586:     *blocc++ = *in++;
                   1587:   }
                   1588: 
                   1589:   *blocc='\0';
                   1590:   return t;
                   1591: }
1.137     brouard  1592: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1593: {
1.187     brouard  1594:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1595:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1596:      gives blocc="abcdef2ghi" and alocc="j".
                   1597:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1598:   */
                   1599:   char *s, *t;
                   1600:   t=in;s=in;
                   1601:   while (*in != '\0'){
                   1602:     while( *in == occ){
                   1603:       *blocc++ = *in++;
                   1604:       s=in;
                   1605:     }
                   1606:     *blocc++ = *in++;
                   1607:   }
                   1608:   if (s == t) /* occ not found */
                   1609:     *(blocc-(in-s))='\0';
                   1610:   else
                   1611:     *(blocc-(in-s)-1)='\0';
                   1612:   in=s;
                   1613:   while ( *in != '\0'){
                   1614:     *alocc++ = *in++;
                   1615:   }
                   1616: 
                   1617:   *alocc='\0';
                   1618:   return s;
                   1619: }
                   1620: 
1.126     brouard  1621: int nbocc(char *s, char occ)
                   1622: {
                   1623:   int i,j=0;
                   1624:   int lg=20;
                   1625:   i=0;
                   1626:   lg=strlen(s);
                   1627:   for(i=0; i<= lg; i++) {
1.234     brouard  1628:     if  (s[i] == occ ) j++;
1.126     brouard  1629:   }
                   1630:   return j;
                   1631: }
                   1632: 
1.137     brouard  1633: /* void cutv(char *u,char *v, char*t, char occ) */
                   1634: /* { */
                   1635: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1636: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1637: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1638: /*   int i,lg,j,p=0; */
                   1639: /*   i=0; */
                   1640: /*   lg=strlen(t); */
                   1641: /*   for(j=0; j<=lg-1; j++) { */
                   1642: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1643: /*   } */
1.126     brouard  1644: 
1.137     brouard  1645: /*   for(j=0; j<p; j++) { */
                   1646: /*     (u[j] = t[j]); */
                   1647: /*   } */
                   1648: /*      u[p]='\0'; */
1.126     brouard  1649: 
1.137     brouard  1650: /*    for(j=0; j<= lg; j++) { */
                   1651: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1652: /*   } */
                   1653: /* } */
1.126     brouard  1654: 
1.160     brouard  1655: #ifdef _WIN32
                   1656: char * strsep(char **pp, const char *delim)
                   1657: {
                   1658:   char *p, *q;
                   1659:          
                   1660:   if ((p = *pp) == NULL)
                   1661:     return 0;
                   1662:   if ((q = strpbrk (p, delim)) != NULL)
                   1663:   {
                   1664:     *pp = q + 1;
                   1665:     *q = '\0';
                   1666:   }
                   1667:   else
                   1668:     *pp = 0;
                   1669:   return p;
                   1670: }
                   1671: #endif
                   1672: 
1.126     brouard  1673: /********************** nrerror ********************/
                   1674: 
                   1675: void nrerror(char error_text[])
                   1676: {
                   1677:   fprintf(stderr,"ERREUR ...\n");
                   1678:   fprintf(stderr,"%s\n",error_text);
                   1679:   exit(EXIT_FAILURE);
                   1680: }
                   1681: /*********************** vector *******************/
                   1682: double *vector(int nl, int nh)
                   1683: {
                   1684:   double *v;
                   1685:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1686:   if (!v) nrerror("allocation failure in vector");
                   1687:   return v-nl+NR_END;
                   1688: }
                   1689: 
                   1690: /************************ free vector ******************/
                   1691: void free_vector(double*v, int nl, int nh)
                   1692: {
                   1693:   free((FREE_ARG)(v+nl-NR_END));
                   1694: }
                   1695: 
                   1696: /************************ivector *******************************/
                   1697: int *ivector(long nl,long nh)
                   1698: {
                   1699:   int *v;
                   1700:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1701:   if (!v) nrerror("allocation failure in ivector");
                   1702:   return v-nl+NR_END;
                   1703: }
                   1704: 
                   1705: /******************free ivector **************************/
                   1706: void free_ivector(int *v, long nl, long nh)
                   1707: {
                   1708:   free((FREE_ARG)(v+nl-NR_END));
                   1709: }
                   1710: 
                   1711: /************************lvector *******************************/
                   1712: long *lvector(long nl,long nh)
                   1713: {
                   1714:   long *v;
                   1715:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1716:   if (!v) nrerror("allocation failure in ivector");
                   1717:   return v-nl+NR_END;
                   1718: }
                   1719: 
                   1720: /******************free lvector **************************/
                   1721: void free_lvector(long *v, long nl, long nh)
                   1722: {
                   1723:   free((FREE_ARG)(v+nl-NR_END));
                   1724: }
                   1725: 
                   1726: /******************* imatrix *******************************/
                   1727: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1728:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1729: { 
                   1730:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1731:   int **m; 
                   1732:   
                   1733:   /* allocate pointers to rows */ 
                   1734:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1735:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1736:   m += NR_END; 
                   1737:   m -= nrl; 
                   1738:   
                   1739:   
                   1740:   /* allocate rows and set pointers to them */ 
                   1741:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1742:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1743:   m[nrl] += NR_END; 
                   1744:   m[nrl] -= ncl; 
                   1745:   
                   1746:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1747:   
                   1748:   /* return pointer to array of pointers to rows */ 
                   1749:   return m; 
                   1750: } 
                   1751: 
                   1752: /****************** free_imatrix *************************/
                   1753: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1754:       int **m;
                   1755:       long nch,ncl,nrh,nrl; 
                   1756:      /* free an int matrix allocated by imatrix() */ 
                   1757: { 
                   1758:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1759:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1760: } 
                   1761: 
                   1762: /******************* matrix *******************************/
                   1763: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1764: {
                   1765:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1766:   double **m;
                   1767: 
                   1768:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1769:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1770:   m += NR_END;
                   1771:   m -= nrl;
                   1772: 
                   1773:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1774:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1775:   m[nrl] += NR_END;
                   1776:   m[nrl] -= ncl;
                   1777: 
                   1778:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1779:   return m;
1.145     brouard  1780:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1781: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1782: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1783:    */
                   1784: }
                   1785: 
                   1786: /*************************free matrix ************************/
                   1787: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1788: {
                   1789:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1790:   free((FREE_ARG)(m+nrl-NR_END));
                   1791: }
                   1792: 
                   1793: /******************* ma3x *******************************/
                   1794: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1795: {
                   1796:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1797:   double ***m;
                   1798: 
                   1799:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1800:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1801:   m += NR_END;
                   1802:   m -= nrl;
                   1803: 
                   1804:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1805:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1806:   m[nrl] += NR_END;
                   1807:   m[nrl] -= ncl;
                   1808: 
                   1809:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1810: 
                   1811:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1812:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1813:   m[nrl][ncl] += NR_END;
                   1814:   m[nrl][ncl] -= nll;
                   1815:   for (j=ncl+1; j<=nch; j++) 
                   1816:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1817:   
                   1818:   for (i=nrl+1; i<=nrh; i++) {
                   1819:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1820:     for (j=ncl+1; j<=nch; j++) 
                   1821:       m[i][j]=m[i][j-1]+nlay;
                   1822:   }
                   1823:   return m; 
                   1824:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1825:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1826:   */
                   1827: }
                   1828: 
                   1829: /*************************free ma3x ************************/
                   1830: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1831: {
                   1832:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1833:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1834:   free((FREE_ARG)(m+nrl-NR_END));
                   1835: }
                   1836: 
                   1837: /*************** function subdirf ***********/
                   1838: char *subdirf(char fileres[])
                   1839: {
                   1840:   /* Caution optionfilefiname is hidden */
                   1841:   strcpy(tmpout,optionfilefiname);
                   1842:   strcat(tmpout,"/"); /* Add to the right */
                   1843:   strcat(tmpout,fileres);
                   1844:   return tmpout;
                   1845: }
                   1846: 
                   1847: /*************** function subdirf2 ***********/
                   1848: char *subdirf2(char fileres[], char *preop)
                   1849: {
                   1850:   
                   1851:   /* Caution optionfilefiname is hidden */
                   1852:   strcpy(tmpout,optionfilefiname);
                   1853:   strcat(tmpout,"/");
                   1854:   strcat(tmpout,preop);
                   1855:   strcat(tmpout,fileres);
                   1856:   return tmpout;
                   1857: }
                   1858: 
                   1859: /*************** function subdirf3 ***********/
                   1860: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1861: {
                   1862:   
                   1863:   /* Caution optionfilefiname is hidden */
                   1864:   strcpy(tmpout,optionfilefiname);
                   1865:   strcat(tmpout,"/");
                   1866:   strcat(tmpout,preop);
                   1867:   strcat(tmpout,preop2);
                   1868:   strcat(tmpout,fileres);
                   1869:   return tmpout;
                   1870: }
1.213     brouard  1871:  
                   1872: /*************** function subdirfext ***********/
                   1873: char *subdirfext(char fileres[], char *preop, char *postop)
                   1874: {
                   1875:   
                   1876:   strcpy(tmpout,preop);
                   1877:   strcat(tmpout,fileres);
                   1878:   strcat(tmpout,postop);
                   1879:   return tmpout;
                   1880: }
1.126     brouard  1881: 
1.213     brouard  1882: /*************** function subdirfext3 ***********/
                   1883: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1884: {
                   1885:   
                   1886:   /* Caution optionfilefiname is hidden */
                   1887:   strcpy(tmpout,optionfilefiname);
                   1888:   strcat(tmpout,"/");
                   1889:   strcat(tmpout,preop);
                   1890:   strcat(tmpout,fileres);
                   1891:   strcat(tmpout,postop);
                   1892:   return tmpout;
                   1893: }
                   1894:  
1.162     brouard  1895: char *asc_diff_time(long time_sec, char ascdiff[])
                   1896: {
                   1897:   long sec_left, days, hours, minutes;
                   1898:   days = (time_sec) / (60*60*24);
                   1899:   sec_left = (time_sec) % (60*60*24);
                   1900:   hours = (sec_left) / (60*60) ;
                   1901:   sec_left = (sec_left) %(60*60);
                   1902:   minutes = (sec_left) /60;
                   1903:   sec_left = (sec_left) % (60);
                   1904:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1905:   return ascdiff;
                   1906: }
                   1907: 
1.126     brouard  1908: /***************** f1dim *************************/
                   1909: extern int ncom; 
                   1910: extern double *pcom,*xicom;
                   1911: extern double (*nrfunc)(double []); 
                   1912:  
                   1913: double f1dim(double x) 
                   1914: { 
                   1915:   int j; 
                   1916:   double f;
                   1917:   double *xt; 
                   1918:  
                   1919:   xt=vector(1,ncom); 
                   1920:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1921:   f=(*nrfunc)(xt); 
                   1922:   free_vector(xt,1,ncom); 
                   1923:   return f; 
                   1924: } 
                   1925: 
                   1926: /*****************brent *************************/
                   1927: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1928: {
                   1929:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1930:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1931:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1932:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1933:    * returned function value. 
                   1934:   */
1.126     brouard  1935:   int iter; 
                   1936:   double a,b,d,etemp;
1.159     brouard  1937:   double fu=0,fv,fw,fx;
1.164     brouard  1938:   double ftemp=0.;
1.126     brouard  1939:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1940:   double e=0.0; 
                   1941:  
                   1942:   a=(ax < cx ? ax : cx); 
                   1943:   b=(ax > cx ? ax : cx); 
                   1944:   x=w=v=bx; 
                   1945:   fw=fv=fx=(*f)(x); 
                   1946:   for (iter=1;iter<=ITMAX;iter++) { 
                   1947:     xm=0.5*(a+b); 
                   1948:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1949:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1950:     printf(".");fflush(stdout);
                   1951:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1952: #ifdef DEBUGBRENT
1.126     brouard  1953:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1954:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1955:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1956: #endif
                   1957:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1958:       *xmin=x; 
                   1959:       return fx; 
                   1960:     } 
                   1961:     ftemp=fu;
                   1962:     if (fabs(e) > tol1) { 
                   1963:       r=(x-w)*(fx-fv); 
                   1964:       q=(x-v)*(fx-fw); 
                   1965:       p=(x-v)*q-(x-w)*r; 
                   1966:       q=2.0*(q-r); 
                   1967:       if (q > 0.0) p = -p; 
                   1968:       q=fabs(q); 
                   1969:       etemp=e; 
                   1970:       e=d; 
                   1971:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1972:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1973:       else { 
1.224     brouard  1974:                                d=p/q; 
                   1975:                                u=x+d; 
                   1976:                                if (u-a < tol2 || b-u < tol2) 
                   1977:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1978:       } 
                   1979:     } else { 
                   1980:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1981:     } 
                   1982:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1983:     fu=(*f)(u); 
                   1984:     if (fu <= fx) { 
                   1985:       if (u >= x) a=x; else b=x; 
                   1986:       SHFT(v,w,x,u) 
1.183     brouard  1987:       SHFT(fv,fw,fx,fu) 
                   1988:     } else { 
                   1989:       if (u < x) a=u; else b=u; 
                   1990:       if (fu <= fw || w == x) { 
1.224     brouard  1991:                                v=w; 
                   1992:                                w=u; 
                   1993:                                fv=fw; 
                   1994:                                fw=fu; 
1.183     brouard  1995:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  1996:                                v=u; 
                   1997:                                fv=fu; 
1.183     brouard  1998:       } 
                   1999:     } 
1.126     brouard  2000:   } 
                   2001:   nrerror("Too many iterations in brent"); 
                   2002:   *xmin=x; 
                   2003:   return fx; 
                   2004: } 
                   2005: 
                   2006: /****************** mnbrak ***********************/
                   2007: 
                   2008: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   2009:            double (*func)(double)) 
1.183     brouard  2010: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   2011: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   2012: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   2013: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   2014:    */
1.126     brouard  2015:   double ulim,u,r,q, dum;
                   2016:   double fu; 
1.187     brouard  2017: 
                   2018:   double scale=10.;
                   2019:   int iterscale=0;
                   2020: 
                   2021:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   2022:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   2023: 
                   2024: 
                   2025:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   2026:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   2027:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   2028:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   2029:   /* } */
                   2030: 
1.126     brouard  2031:   if (*fb > *fa) { 
                   2032:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  2033:     SHFT(dum,*fb,*fa,dum) 
                   2034:   } 
1.126     brouard  2035:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   2036:   *fc=(*func)(*cx); 
1.183     brouard  2037: #ifdef DEBUG
1.224     brouard  2038:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   2039:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  2040: #endif
1.224     brouard  2041:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  2042:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  2043:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  2044:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  2045:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   2046:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   2047:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  2048:       fu=(*func)(u); 
1.163     brouard  2049: #ifdef DEBUG
                   2050:       /* f(x)=A(x-u)**2+f(u) */
                   2051:       double A, fparabu; 
                   2052:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2053:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  2054:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   2055:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  2056:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   2057:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   2058:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   2059:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  2060: #endif 
1.184     brouard  2061: #ifdef MNBRAKORIGINAL
1.183     brouard  2062: #else
1.191     brouard  2063: /*       if (fu > *fc) { */
                   2064: /* #ifdef DEBUG */
                   2065: /*       printf("mnbrak4  fu > fc \n"); */
                   2066: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   2067: /* #endif */
                   2068: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2069: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2070: /*     dum=u; /\* Shifting c and u *\/ */
                   2071: /*     u = *cx; */
                   2072: /*     *cx = dum; */
                   2073: /*     dum = fu; */
                   2074: /*     fu = *fc; */
                   2075: /*     *fc =dum; */
                   2076: /*       } else { /\* end *\/ */
                   2077: /* #ifdef DEBUG */
                   2078: /*       printf("mnbrak3  fu < fc \n"); */
                   2079: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2080: /* #endif */
                   2081: /*     dum=u; /\* Shifting c and u *\/ */
                   2082: /*     u = *cx; */
                   2083: /*     *cx = dum; */
                   2084: /*     dum = fu; */
                   2085: /*     fu = *fc; */
                   2086: /*     *fc =dum; */
                   2087: /*       } */
1.224     brouard  2088: #ifdef DEBUGMNBRAK
                   2089:                 double A, fparabu; 
                   2090:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2091:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2092:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2093:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2094: #endif
1.191     brouard  2095:       dum=u; /* Shifting c and u */
                   2096:       u = *cx;
                   2097:       *cx = dum;
                   2098:       dum = fu;
                   2099:       fu = *fc;
                   2100:       *fc =dum;
1.183     brouard  2101: #endif
1.162     brouard  2102:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2103: #ifdef DEBUG
1.224     brouard  2104:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2105:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2106: #endif
1.126     brouard  2107:       fu=(*func)(u); 
                   2108:       if (fu < *fc) { 
1.183     brouard  2109: #ifdef DEBUG
1.224     brouard  2110:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2111:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2112: #endif
                   2113:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2114:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2115: #ifdef DEBUG
                   2116:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2117: #endif
                   2118:       } 
1.162     brouard  2119:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2120: #ifdef DEBUG
1.224     brouard  2121:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2122:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2123: #endif
1.126     brouard  2124:       u=ulim; 
                   2125:       fu=(*func)(u); 
1.183     brouard  2126:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2127: #ifdef DEBUG
1.224     brouard  2128:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2129:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2130: #endif
1.126     brouard  2131:       u=(*cx)+GOLD*(*cx-*bx); 
                   2132:       fu=(*func)(u); 
1.224     brouard  2133: #ifdef DEBUG
                   2134:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2135:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2136: #endif
1.183     brouard  2137:     } /* end tests */
1.126     brouard  2138:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2139:     SHFT(*fa,*fb,*fc,fu) 
                   2140: #ifdef DEBUG
1.224     brouard  2141:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2142:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2143: #endif
                   2144:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2145: } 
                   2146: 
                   2147: /*************** linmin ************************/
1.162     brouard  2148: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2149: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2150: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2151: the value of func at the returned location p . This is actually all accomplished by calling the
                   2152: routines mnbrak and brent .*/
1.126     brouard  2153: int ncom; 
                   2154: double *pcom,*xicom;
                   2155: double (*nrfunc)(double []); 
                   2156:  
1.224     brouard  2157: #ifdef LINMINORIGINAL
1.126     brouard  2158: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2159: #else
                   2160: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2161: #endif
1.126     brouard  2162: { 
                   2163:   double brent(double ax, double bx, double cx, 
                   2164:               double (*f)(double), double tol, double *xmin); 
                   2165:   double f1dim(double x); 
                   2166:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2167:              double *fc, double (*func)(double)); 
                   2168:   int j; 
                   2169:   double xx,xmin,bx,ax; 
                   2170:   double fx,fb,fa;
1.187     brouard  2171: 
1.203     brouard  2172: #ifdef LINMINORIGINAL
                   2173: #else
                   2174:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2175: #endif
                   2176:   
1.126     brouard  2177:   ncom=n; 
                   2178:   pcom=vector(1,n); 
                   2179:   xicom=vector(1,n); 
                   2180:   nrfunc=func; 
                   2181:   for (j=1;j<=n;j++) { 
                   2182:     pcom[j]=p[j]; 
1.202     brouard  2183:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2184:   } 
1.187     brouard  2185: 
1.203     brouard  2186: #ifdef LINMINORIGINAL
                   2187:   xx=1.;
                   2188: #else
                   2189:   axs=0.0;
                   2190:   xxs=1.;
                   2191:   do{
                   2192:     xx= xxs;
                   2193: #endif
1.187     brouard  2194:     ax=0.;
                   2195:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2196:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2197:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2198:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2199:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2200:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2201:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2202: #ifdef LINMINORIGINAL
                   2203: #else
                   2204:     if (fx != fx){
1.224     brouard  2205:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2206:                        printf("|");
                   2207:                        fprintf(ficlog,"|");
1.203     brouard  2208: #ifdef DEBUGLINMIN
1.224     brouard  2209:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2210: #endif
                   2211:     }
1.224     brouard  2212:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2213: #endif
                   2214:   
1.191     brouard  2215: #ifdef DEBUGLINMIN
                   2216:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2217:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2218: #endif
1.224     brouard  2219: #ifdef LINMINORIGINAL
                   2220: #else
                   2221:        if(fb == fx){ /* Flat function in the direction */
                   2222:                xmin=xx;
                   2223:     *flat=1;
                   2224:        }else{
                   2225:     *flat=0;
                   2226: #endif
                   2227:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2228:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2229:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2230:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2231:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2232:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2233: #ifdef DEBUG
1.224     brouard  2234:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2235:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2236: #endif
                   2237: #ifdef LINMINORIGINAL
                   2238: #else
                   2239:                        }
1.126     brouard  2240: #endif
1.191     brouard  2241: #ifdef DEBUGLINMIN
                   2242:   printf("linmin end ");
1.202     brouard  2243:   fprintf(ficlog,"linmin end ");
1.191     brouard  2244: #endif
1.126     brouard  2245:   for (j=1;j<=n;j++) { 
1.203     brouard  2246: #ifdef LINMINORIGINAL
                   2247:     xi[j] *= xmin; 
                   2248: #else
                   2249: #ifdef DEBUGLINMIN
                   2250:     if(xxs <1.0)
                   2251:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2252: #endif
                   2253:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2254: #ifdef DEBUGLINMIN
                   2255:     if(xxs <1.0)
                   2256:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2257: #endif
                   2258: #endif
1.187     brouard  2259:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2260:   } 
1.191     brouard  2261: #ifdef DEBUGLINMIN
1.203     brouard  2262:   printf("\n");
1.191     brouard  2263:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2264:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2265:   for (j=1;j<=n;j++) { 
1.202     brouard  2266:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2267:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2268:     if(j % ncovmodel == 0){
1.191     brouard  2269:       printf("\n");
1.202     brouard  2270:       fprintf(ficlog,"\n");
                   2271:     }
1.191     brouard  2272:   }
1.203     brouard  2273: #else
1.191     brouard  2274: #endif
1.126     brouard  2275:   free_vector(xicom,1,n); 
                   2276:   free_vector(pcom,1,n); 
                   2277: } 
                   2278: 
                   2279: 
                   2280: /*************** powell ************************/
1.162     brouard  2281: /*
                   2282: Minimization of a function func of n variables. Input consists of an initial starting point
                   2283: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2284: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2285: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2286: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2287: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2288:  */
1.224     brouard  2289: #ifdef LINMINORIGINAL
                   2290: #else
                   2291:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2292:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2293: #endif
1.126     brouard  2294: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2295:            double (*func)(double [])) 
                   2296: { 
1.224     brouard  2297: #ifdef LINMINORIGINAL
                   2298:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2299:              double (*func)(double [])); 
1.224     brouard  2300: #else 
1.241     brouard  2301:  void linmin(double p[], double xi[], int n, double *fret,
                   2302:             double (*func)(double []),int *flat); 
1.224     brouard  2303: #endif
1.239     brouard  2304:  int i,ibig,j,jk,k; 
1.126     brouard  2305:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2306:   double directest;
1.126     brouard  2307:   double fp,fptt;
                   2308:   double *xits;
                   2309:   int niterf, itmp;
1.224     brouard  2310: #ifdef LINMINORIGINAL
                   2311: #else
                   2312: 
                   2313:   flatdir=ivector(1,n); 
                   2314:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2315: #endif
1.126     brouard  2316: 
                   2317:   pt=vector(1,n); 
                   2318:   ptt=vector(1,n); 
                   2319:   xit=vector(1,n); 
                   2320:   xits=vector(1,n); 
                   2321:   *fret=(*func)(p); 
                   2322:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2323:   rcurr_time = time(NULL);  
1.126     brouard  2324:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2325:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2326:     ibig=0; 
                   2327:     del=0.0; 
1.157     brouard  2328:     rlast_time=rcurr_time;
                   2329:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2330:     rcurr_time = time(NULL);  
                   2331:     curr_time = *localtime(&rcurr_time);
                   2332:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2333:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2334: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2335:     for (i=1;i<=n;i++) {
1.126     brouard  2336:       fprintf(ficrespow," %.12lf", p[i]);
                   2337:     }
1.239     brouard  2338:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2339:     printf("\n#model=  1      +     age ");
                   2340:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2341:     if(nagesqr==1){
1.241     brouard  2342:        printf("  + age*age  ");
                   2343:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2344:     }
                   2345:     for(j=1;j <=ncovmodel-2;j++){
                   2346:       if(Typevar[j]==0) {
                   2347:        printf("  +      V%d  ",Tvar[j]);
                   2348:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2349:       }else if(Typevar[j]==1) {
                   2350:        printf("  +    V%d*age ",Tvar[j]);
                   2351:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2352:       }else if(Typevar[j]==2) {
                   2353:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2354:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2355:       }
                   2356:     }
1.126     brouard  2357:     printf("\n");
1.239     brouard  2358: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2359: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2360:     fprintf(ficlog,"\n");
1.239     brouard  2361:     for(i=1,jk=1; i <=nlstate; i++){
                   2362:       for(k=1; k <=(nlstate+ndeath); k++){
                   2363:        if (k != i) {
                   2364:          printf("%d%d ",i,k);
                   2365:          fprintf(ficlog,"%d%d ",i,k);
                   2366:          for(j=1; j <=ncovmodel; j++){
                   2367:            printf("%12.7f ",p[jk]);
                   2368:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2369:            jk++; 
                   2370:          }
                   2371:          printf("\n");
                   2372:          fprintf(ficlog,"\n");
                   2373:        }
                   2374:       }
                   2375:     }
1.241     brouard  2376:     if(*iter <=3 && *iter >1){
1.157     brouard  2377:       tml = *localtime(&rcurr_time);
                   2378:       strcpy(strcurr,asctime(&tml));
                   2379:       rforecast_time=rcurr_time; 
1.126     brouard  2380:       itmp = strlen(strcurr);
                   2381:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2382:        strcurr[itmp-1]='\0';
1.162     brouard  2383:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2384:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2385:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2386:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2387:        forecast_time = *localtime(&rforecast_time);
                   2388:        strcpy(strfor,asctime(&forecast_time));
                   2389:        itmp = strlen(strfor);
                   2390:        if(strfor[itmp-1]=='\n')
                   2391:          strfor[itmp-1]='\0';
                   2392:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2393:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2394:       }
                   2395:     }
1.187     brouard  2396:     for (i=1;i<=n;i++) { /* For each direction i */
                   2397:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2398:       fptt=(*fret); 
                   2399: #ifdef DEBUG
1.203     brouard  2400:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2401:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2402: #endif
1.203     brouard  2403:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2404:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2405: #ifdef LINMINORIGINAL
1.188     brouard  2406:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2407: #else
                   2408:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2409:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2410: #endif
                   2411:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2412:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2413:                                /* because that direction will be replaced unless the gain del is small */
                   2414:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2415:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2416:                                /* with the new direction. */
                   2417:                                del=fabs(fptt-(*fret)); 
                   2418:                                ibig=i; 
1.126     brouard  2419:       } 
                   2420: #ifdef DEBUG
                   2421:       printf("%d %.12e",i,(*fret));
                   2422:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2423:       for (j=1;j<=n;j++) {
1.224     brouard  2424:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2425:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2426:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2427:       }
                   2428:       for(j=1;j<=n;j++) {
1.225     brouard  2429:                                printf(" p(%d)=%.12e",j,p[j]);
                   2430:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2431:       }
                   2432:       printf("\n");
                   2433:       fprintf(ficlog,"\n");
                   2434: #endif
1.187     brouard  2435:     } /* end loop on each direction i */
                   2436:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2437:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2438:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2439:       for(j=1;j<=n;j++) {
1.302     brouard  2440:        if(flatdir[j] >0){
                   2441:          printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2442:          fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2443:        }
                   2444:        /* printf("\n"); */
                   2445:        /* fprintf(ficlog,"\n"); */
                   2446:       }
1.243     brouard  2447:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2448:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2449:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2450:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2451:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2452:       /* decreased of more than 3.84  */
                   2453:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2454:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2455:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2456:                        
1.188     brouard  2457:       /* Starting the program with initial values given by a former maximization will simply change */
                   2458:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2459:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2460:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2461: #ifdef DEBUG
                   2462:       int k[2],l;
                   2463:       k[0]=1;
                   2464:       k[1]=-1;
                   2465:       printf("Max: %.12e",(*func)(p));
                   2466:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2467:       for (j=1;j<=n;j++) {
                   2468:        printf(" %.12e",p[j]);
                   2469:        fprintf(ficlog," %.12e",p[j]);
                   2470:       }
                   2471:       printf("\n");
                   2472:       fprintf(ficlog,"\n");
                   2473:       for(l=0;l<=1;l++) {
                   2474:        for (j=1;j<=n;j++) {
                   2475:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2476:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2477:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2478:        }
                   2479:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2480:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2481:       }
                   2482: #endif
                   2483: 
1.224     brouard  2484: #ifdef LINMINORIGINAL
                   2485: #else
                   2486:       free_ivector(flatdir,1,n); 
                   2487: #endif
1.126     brouard  2488:       free_vector(xit,1,n); 
                   2489:       free_vector(xits,1,n); 
                   2490:       free_vector(ptt,1,n); 
                   2491:       free_vector(pt,1,n); 
                   2492:       return; 
1.192     brouard  2493:     } /* enough precision */ 
1.240     brouard  2494:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2495:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2496:       ptt[j]=2.0*p[j]-pt[j]; 
                   2497:       xit[j]=p[j]-pt[j]; 
                   2498:       pt[j]=p[j]; 
                   2499:     } 
1.181     brouard  2500:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2501: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2502:                if (*iter <=4) {
1.225     brouard  2503: #else
                   2504: #endif
1.224     brouard  2505: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2506: #else
1.161     brouard  2507:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2508: #endif
1.162     brouard  2509:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2510:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2511:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2512:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2513:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2514:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2515:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2516:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2517:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2518:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2519:       /* mu² and del² are equal when f3=f1 */
                   2520:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2521:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2522:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2523:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2524: #ifdef NRCORIGINAL
                   2525:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2526: #else
                   2527:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2528:       t= t- del*SQR(fp-fptt);
1.183     brouard  2529: #endif
1.202     brouard  2530:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2531: #ifdef DEBUG
1.181     brouard  2532:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2533:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2534:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2535:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2536:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2537:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2538:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2539:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2540: #endif
1.183     brouard  2541: #ifdef POWELLORIGINAL
                   2542:       if (t < 0.0) { /* Then we use it for new direction */
                   2543: #else
1.182     brouard  2544:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2545:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2546:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2547:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2548:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2549:       } 
1.181     brouard  2550:       if (directest < 0.0) { /* Then we use it for new direction */
                   2551: #endif
1.191     brouard  2552: #ifdef DEBUGLINMIN
1.234     brouard  2553:        printf("Before linmin in direction P%d-P0\n",n);
                   2554:        for (j=1;j<=n;j++) {
                   2555:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2556:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2557:          if(j % ncovmodel == 0){
                   2558:            printf("\n");
                   2559:            fprintf(ficlog,"\n");
                   2560:          }
                   2561:        }
1.224     brouard  2562: #endif
                   2563: #ifdef LINMINORIGINAL
1.234     brouard  2564:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2565: #else
1.234     brouard  2566:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2567:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2568: #endif
1.234     brouard  2569:        
1.191     brouard  2570: #ifdef DEBUGLINMIN
1.234     brouard  2571:        for (j=1;j<=n;j++) { 
                   2572:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2573:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2574:          if(j % ncovmodel == 0){
                   2575:            printf("\n");
                   2576:            fprintf(ficlog,"\n");
                   2577:          }
                   2578:        }
1.224     brouard  2579: #endif
1.234     brouard  2580:        for (j=1;j<=n;j++) { 
                   2581:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2582:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2583:        }
1.224     brouard  2584: #ifdef LINMINORIGINAL
                   2585: #else
1.234     brouard  2586:        for (j=1, flatd=0;j<=n;j++) {
                   2587:          if(flatdir[j]>0)
                   2588:            flatd++;
                   2589:        }
                   2590:        if(flatd >0){
1.255     brouard  2591:          printf("%d flat directions: ",flatd);
                   2592:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2593:          for (j=1;j<=n;j++) { 
                   2594:            if(flatdir[j]>0){
                   2595:              printf("%d ",j);
                   2596:              fprintf(ficlog,"%d ",j);
                   2597:            }
                   2598:          }
                   2599:          printf("\n");
                   2600:          fprintf(ficlog,"\n");
                   2601:        }
1.191     brouard  2602: #endif
1.234     brouard  2603:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2604:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2605:        
1.126     brouard  2606: #ifdef DEBUG
1.234     brouard  2607:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2608:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2609:        for(j=1;j<=n;j++){
                   2610:          printf(" %lf",xit[j]);
                   2611:          fprintf(ficlog," %lf",xit[j]);
                   2612:        }
                   2613:        printf("\n");
                   2614:        fprintf(ficlog,"\n");
1.126     brouard  2615: #endif
1.192     brouard  2616:       } /* end of t or directest negative */
1.224     brouard  2617: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2618: #else
1.234     brouard  2619:       } /* end if (fptt < fp)  */
1.192     brouard  2620: #endif
1.225     brouard  2621: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2622:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2623: #else
1.224     brouard  2624: #endif
1.234     brouard  2625:                } /* loop iteration */ 
1.126     brouard  2626: } 
1.234     brouard  2627:   
1.126     brouard  2628: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2629:   
1.235     brouard  2630:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2631:   {
1.279     brouard  2632:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2633:      *   (and selected quantitative values in nres)
                   2634:      *  by left multiplying the unit
                   2635:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2636:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2637:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2638:      * or prevalence in state 1, prevalence in state 2, 0
                   2639:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2640:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2641:      * Output is prlim.
                   2642:      * Initial matrix pimij 
                   2643:      */
1.206     brouard  2644:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2645:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2646:   /*  0,                   0                  , 1} */
                   2647:   /*
                   2648:    * and after some iteration: */
                   2649:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2650:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2651:   /*  0,                   0                  , 1} */
                   2652:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2653:   /* {0.51571254859325999, 0.4842874514067399, */
                   2654:   /*  0.51326036147820708, 0.48673963852179264} */
                   2655:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2656:     
1.126     brouard  2657:   int i, ii,j,k;
1.209     brouard  2658:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2659:   /* double **matprod2(); */ /* test */
1.218     brouard  2660:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2661:   double **newm;
1.209     brouard  2662:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2663:   int ncvloop=0;
1.288     brouard  2664:   int first=0;
1.169     brouard  2665:   
1.209     brouard  2666:   min=vector(1,nlstate);
                   2667:   max=vector(1,nlstate);
                   2668:   meandiff=vector(1,nlstate);
                   2669: 
1.218     brouard  2670:        /* Starting with matrix unity */
1.126     brouard  2671:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2672:     for (j=1;j<=nlstate+ndeath;j++){
                   2673:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2674:     }
1.169     brouard  2675:   
                   2676:   cov[1]=1.;
                   2677:   
                   2678:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2679:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2680:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2681:     ncvloop++;
1.126     brouard  2682:     newm=savm;
                   2683:     /* Covariates have to be included here again */
1.138     brouard  2684:     cov[2]=agefin;
1.187     brouard  2685:     if(nagesqr==1)
                   2686:       cov[3]= agefin*agefin;;
1.234     brouard  2687:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2688:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2689:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2690:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2691:     }
                   2692:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2693:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2694:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2695:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2696:     }
1.237     brouard  2697:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2698:       if(Dummy[Tvar[Tage[k]]]){
                   2699:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2700:       } else{
1.235     brouard  2701:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2702:       }
1.235     brouard  2703:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2704:     }
1.237     brouard  2705:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2706:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2707:       if(Dummy[Tvard[k][1]==0]){
                   2708:        if(Dummy[Tvard[k][2]==0]){
                   2709:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2710:        }else{
                   2711:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2712:        }
                   2713:       }else{
                   2714:        if(Dummy[Tvard[k][2]==0]){
                   2715:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2716:        }else{
                   2717:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2718:        }
                   2719:       }
1.234     brouard  2720:     }
1.138     brouard  2721:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2722:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2723:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2724:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2725:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2726:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2727:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2728:     
1.126     brouard  2729:     savm=oldm;
                   2730:     oldm=newm;
1.209     brouard  2731: 
                   2732:     for(j=1; j<=nlstate; j++){
                   2733:       max[j]=0.;
                   2734:       min[j]=1.;
                   2735:     }
                   2736:     for(i=1;i<=nlstate;i++){
                   2737:       sumnew=0;
                   2738:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2739:       for(j=1; j<=nlstate; j++){ 
                   2740:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2741:        max[j]=FMAX(max[j],prlim[i][j]);
                   2742:        min[j]=FMIN(min[j],prlim[i][j]);
                   2743:       }
                   2744:     }
                   2745: 
1.126     brouard  2746:     maxmax=0.;
1.209     brouard  2747:     for(j=1; j<=nlstate; j++){
                   2748:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2749:       maxmax=FMAX(maxmax,meandiff[j]);
                   2750:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2751:     } /* j loop */
1.203     brouard  2752:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2753:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2754:     if(maxmax < ftolpl){
1.209     brouard  2755:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2756:       free_vector(min,1,nlstate);
                   2757:       free_vector(max,1,nlstate);
                   2758:       free_vector(meandiff,1,nlstate);
1.126     brouard  2759:       return prlim;
                   2760:     }
1.288     brouard  2761:   } /* agefin loop */
1.208     brouard  2762:     /* After some age loop it doesn't converge */
1.288     brouard  2763:   if(!first){
                   2764:     first=1;
                   2765:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2766:   }
                   2767:   fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2768: 
1.209     brouard  2769:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2770:   free_vector(min,1,nlstate);
                   2771:   free_vector(max,1,nlstate);
                   2772:   free_vector(meandiff,1,nlstate);
1.208     brouard  2773:   
1.169     brouard  2774:   return prlim; /* should not reach here */
1.126     brouard  2775: }
                   2776: 
1.217     brouard  2777: 
                   2778:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2779: 
1.218     brouard  2780:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2781:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2782:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2783: {
1.264     brouard  2784:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2785:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2786:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2787:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2788:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2789:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2790:   /* Initial matrix pimij */
                   2791:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2792:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2793:   /*  0,                   0                  , 1} */
                   2794:   /*
                   2795:    * and after some iteration: */
                   2796:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2797:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2798:   /*  0,                   0                  , 1} */
                   2799:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2800:   /* {0.51571254859325999, 0.4842874514067399, */
                   2801:   /*  0.51326036147820708, 0.48673963852179264} */
                   2802:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2803: 
                   2804:   int i, ii,j,k;
1.247     brouard  2805:   int first=0;
1.217     brouard  2806:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2807:   /* double **matprod2(); */ /* test */
                   2808:   double **out, cov[NCOVMAX+1], **bmij();
                   2809:   double **newm;
1.218     brouard  2810:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2811:   double        **oldm, **savm;  /* for use */
                   2812: 
1.217     brouard  2813:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2814:   int ncvloop=0;
                   2815:   
                   2816:   min=vector(1,nlstate);
                   2817:   max=vector(1,nlstate);
                   2818:   meandiff=vector(1,nlstate);
                   2819: 
1.266     brouard  2820:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2821:   oldm=oldms; savm=savms;
                   2822:   
                   2823:   /* Starting with matrix unity */
                   2824:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2825:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2826:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2827:     }
                   2828:   
                   2829:   cov[1]=1.;
                   2830:   
                   2831:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2832:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2833:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2834:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2835:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2836:     ncvloop++;
1.218     brouard  2837:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2838:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2839:     /* Covariates have to be included here again */
                   2840:     cov[2]=agefin;
                   2841:     if(nagesqr==1)
                   2842:       cov[3]= agefin*agefin;;
1.242     brouard  2843:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2844:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2845:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2846:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2847:     }
                   2848:     /* for (k=1; k<=cptcovn;k++) { */
                   2849:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2850:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2851:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2852:     /* } */
                   2853:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2854:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2855:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2856:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2857:     }
                   2858:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2859:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2860:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2861:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2862:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2863:       if(Dummy[Tvar[Tage[k]]]){
                   2864:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2865:       } else{
                   2866:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2867:       }
                   2868:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2869:     }
                   2870:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2871:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2872:       if(Dummy[Tvard[k][1]==0]){
                   2873:        if(Dummy[Tvard[k][2]==0]){
                   2874:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2875:        }else{
                   2876:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2877:        }
                   2878:       }else{
                   2879:        if(Dummy[Tvard[k][2]==0]){
                   2880:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2881:        }else{
                   2882:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2883:        }
                   2884:       }
1.217     brouard  2885:     }
                   2886:     
                   2887:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2888:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2889:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2890:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2891:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2892:                /* ij should be linked to the correct index of cov */
                   2893:                /* age and covariate values ij are in 'cov', but we need to pass
                   2894:                 * ij for the observed prevalence at age and status and covariate
                   2895:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2896:                 */
                   2897:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2898:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2899:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2900:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2901:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2902:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2903:     /*         printf("%d newm= ",i); */
                   2904:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2905:     /*           printf("%f ",newm[i][j]); */
                   2906:     /*         } */
                   2907:     /*         printf("oldm * "); */
                   2908:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2909:     /*           printf("%f ",oldm[i][j]); */
                   2910:     /*         } */
1.268     brouard  2911:     /*         printf(" bmmij "); */
1.266     brouard  2912:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2913:     /*           printf("%f ",pmmij[i][j]); */
                   2914:     /*         } */
                   2915:     /*         printf("\n"); */
                   2916:     /*   } */
                   2917:     /* } */
1.217     brouard  2918:     savm=oldm;
                   2919:     oldm=newm;
1.266     brouard  2920: 
1.217     brouard  2921:     for(j=1; j<=nlstate; j++){
                   2922:       max[j]=0.;
                   2923:       min[j]=1.;
                   2924:     }
                   2925:     for(j=1; j<=nlstate; j++){ 
                   2926:       for(i=1;i<=nlstate;i++){
1.234     brouard  2927:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2928:        bprlim[i][j]= newm[i][j];
                   2929:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2930:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2931:       }
                   2932:     }
1.218     brouard  2933:                
1.217     brouard  2934:     maxmax=0.;
                   2935:     for(i=1; i<=nlstate; i++){
                   2936:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2937:       maxmax=FMAX(maxmax,meandiff[i]);
                   2938:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2939:     } /* i loop */
1.217     brouard  2940:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2941:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2942:     if(maxmax < ftolpl){
1.220     brouard  2943:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2944:       free_vector(min,1,nlstate);
                   2945:       free_vector(max,1,nlstate);
                   2946:       free_vector(meandiff,1,nlstate);
                   2947:       return bprlim;
                   2948:     }
1.288     brouard  2949:   } /* agefin loop */
1.217     brouard  2950:     /* After some age loop it doesn't converge */
1.288     brouard  2951:   if(!first){
1.247     brouard  2952:     first=1;
                   2953:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2954: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2955:   }
                   2956:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2957: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2958:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2959:   free_vector(min,1,nlstate);
                   2960:   free_vector(max,1,nlstate);
                   2961:   free_vector(meandiff,1,nlstate);
                   2962:   
                   2963:   return bprlim; /* should not reach here */
                   2964: }
                   2965: 
1.126     brouard  2966: /*************** transition probabilities ***************/ 
                   2967: 
                   2968: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2969: {
1.138     brouard  2970:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2971:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2972:      model to the ncovmodel covariates (including constant and age).
                   2973:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2974:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2975:      ncth covariate in the global vector x is given by the formula:
                   2976:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2977:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2978:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2979:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2980:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2981:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2982:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2983:   */
                   2984:   double s1, lnpijopii;
1.126     brouard  2985:   /*double t34;*/
1.164     brouard  2986:   int i,j, nc, ii, jj;
1.126     brouard  2987: 
1.223     brouard  2988:   for(i=1; i<= nlstate; i++){
                   2989:     for(j=1; j<i;j++){
                   2990:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   2991:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   2992:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   2993:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2994:       }
                   2995:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   2996:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   2997:     }
                   2998:     for(j=i+1; j<=nlstate+ndeath;j++){
                   2999:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3000:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3001:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3002:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3003:       }
                   3004:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3005:     }
                   3006:   }
1.218     brouard  3007:   
1.223     brouard  3008:   for(i=1; i<= nlstate; i++){
                   3009:     s1=0;
                   3010:     for(j=1; j<i; j++){
                   3011:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3012:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3013:     }
                   3014:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3015:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3016:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3017:     }
                   3018:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3019:     ps[i][i]=1./(s1+1.);
                   3020:     /* Computing other pijs */
                   3021:     for(j=1; j<i; j++)
                   3022:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3023:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3024:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3025:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3026:   } /* end i */
1.218     brouard  3027:   
1.223     brouard  3028:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3029:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3030:       ps[ii][jj]=0;
                   3031:       ps[ii][ii]=1;
                   3032:     }
                   3033:   }
1.294     brouard  3034: 
                   3035: 
1.223     brouard  3036:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3037:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3038:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3039:   /*   } */
                   3040:   /*   printf("\n "); */
                   3041:   /* } */
                   3042:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3043:   /*
                   3044:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  3045:                goto end;*/
1.266     brouard  3046:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  3047: }
                   3048: 
1.218     brouard  3049: /*************** backward transition probabilities ***************/ 
                   3050: 
                   3051:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3052: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3053:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   3054: {
1.302     brouard  3055:   /* Computes the backward probability at age agefin, cov[2], and covariate combination 'ij'. In fact cov is already filled and x too.
1.266     brouard  3056:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  3057:    */
1.218     brouard  3058:   int i, ii, j,k;
1.222     brouard  3059:   
                   3060:   double **out, **pmij();
                   3061:   double sumnew=0.;
1.218     brouard  3062:   double agefin;
1.292     brouard  3063:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  3064:   double **dnewm, **dsavm, **doldm;
                   3065:   double **bbmij;
                   3066:   
1.218     brouard  3067:   doldm=ddoldms; /* global pointers */
1.222     brouard  3068:   dnewm=ddnewms;
                   3069:   dsavm=ddsavms;
                   3070:   
                   3071:   agefin=cov[2];
1.268     brouard  3072:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3073:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3074:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3075:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3076: 
                   3077:   /* P_x */
1.266     brouard  3078:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3079:   /* outputs pmmij which is a stochastic matrix in row */
                   3080: 
                   3081:   /* Diag(w_x) */
1.292     brouard  3082:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3083:   sumnew=0.;
1.269     brouard  3084:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3085:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.297     brouard  3086:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]); */
1.268     brouard  3087:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3088:   }
                   3089:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3090:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3091:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3092:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3093:     }
                   3094:   }else{
                   3095:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3096:       for (j=1;j<=nlstate+ndeath;j++)
                   3097:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3098:     }
                   3099:     /* if(sumnew <0.9){ */
                   3100:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3101:     /* } */
                   3102:   }
                   3103:   k3=0.0;  /* We put the last diagonal to 0 */
                   3104:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3105:       doldm[ii][ii]= k3;
                   3106:   }
                   3107:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3108:   
1.292     brouard  3109:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
                   3110:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3111: 
1.292     brouard  3112:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3113:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3114:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3115:     sumnew=0.;
1.222     brouard  3116:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3117:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3118:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3119:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3120:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3121:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3122:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3123:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3124:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3125:        /* }else */
1.268     brouard  3126:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3127:     } /*End ii */
                   3128:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3129: 
1.292     brouard  3130:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3131:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3132:   /* end bmij */
1.266     brouard  3133:   return ps; /*pointer is unchanged */
1.218     brouard  3134: }
1.217     brouard  3135: /*************** transition probabilities ***************/ 
                   3136: 
1.218     brouard  3137: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3138: {
                   3139:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3140:      computes the probability to be observed in state j being in state i by appying the
                   3141:      model to the ncovmodel covariates (including constant and age).
                   3142:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3143:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3144:      ncth covariate in the global vector x is given by the formula:
                   3145:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3146:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3147:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3148:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3149:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3150:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3151:   */
                   3152:   double s1, lnpijopii;
                   3153:   /*double t34;*/
                   3154:   int i,j, nc, ii, jj;
                   3155: 
1.234     brouard  3156:   for(i=1; i<= nlstate; i++){
                   3157:     for(j=1; j<i;j++){
                   3158:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3159:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3160:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3161:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3162:       }
                   3163:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3164:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3165:     }
                   3166:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3167:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3168:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3169:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3170:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3171:       }
                   3172:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3173:     }
                   3174:   }
                   3175:   
                   3176:   for(i=1; i<= nlstate; i++){
                   3177:     s1=0;
                   3178:     for(j=1; j<i; j++){
                   3179:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3180:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3181:     }
                   3182:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3183:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3184:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3185:     }
                   3186:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3187:     ps[i][i]=1./(s1+1.);
                   3188:     /* Computing other pijs */
                   3189:     for(j=1; j<i; j++)
                   3190:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3191:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3192:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3193:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3194:   } /* end i */
                   3195:   
                   3196:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3197:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3198:       ps[ii][jj]=0;
                   3199:       ps[ii][ii]=1;
                   3200:     }
                   3201:   }
1.296     brouard  3202:   /* Added for prevbcast */ /* Transposed matrix too */
1.234     brouard  3203:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3204:     s1=0.;
                   3205:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3206:       s1+=ps[ii][jj];
                   3207:     }
                   3208:     for(ii=1; ii<= nlstate; ii++){
                   3209:       ps[ii][jj]=ps[ii][jj]/s1;
                   3210:     }
                   3211:   }
                   3212:   /* Transposition */
                   3213:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3214:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3215:       s1=ps[ii][jj];
                   3216:       ps[ii][jj]=ps[jj][ii];
                   3217:       ps[jj][ii]=s1;
                   3218:     }
                   3219:   }
                   3220:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3221:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3222:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3223:   /*   } */
                   3224:   /*   printf("\n "); */
                   3225:   /* } */
                   3226:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3227:   /*
                   3228:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3229:     goto end;*/
                   3230:   return ps;
1.217     brouard  3231: }
                   3232: 
                   3233: 
1.126     brouard  3234: /**************** Product of 2 matrices ******************/
                   3235: 
1.145     brouard  3236: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3237: {
                   3238:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3239:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3240:   /* in, b, out are matrice of pointers which should have been initialized 
                   3241:      before: only the contents of out is modified. The function returns
                   3242:      a pointer to pointers identical to out */
1.145     brouard  3243:   int i, j, k;
1.126     brouard  3244:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3245:     for(k=ncolol; k<=ncoloh; k++){
                   3246:       out[i][k]=0.;
                   3247:       for(j=ncl; j<=nch; j++)
                   3248:        out[i][k] +=in[i][j]*b[j][k];
                   3249:     }
1.126     brouard  3250:   return out;
                   3251: }
                   3252: 
                   3253: 
                   3254: /************* Higher Matrix Product ***************/
                   3255: 
1.235     brouard  3256: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3257: {
1.218     brouard  3258:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3259:      'nhstepm*hstepm*stepm' months (i.e. until
                   3260:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3261:      nhstepm*hstepm matrices. 
                   3262:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3263:      (typically every 2 years instead of every month which is too big 
                   3264:      for the memory).
                   3265:      Model is determined by parameters x and covariates have to be 
                   3266:      included manually here. 
                   3267: 
                   3268:      */
                   3269: 
                   3270:   int i, j, d, h, k;
1.131     brouard  3271:   double **out, cov[NCOVMAX+1];
1.126     brouard  3272:   double **newm;
1.187     brouard  3273:   double agexact;
1.214     brouard  3274:   double agebegin, ageend;
1.126     brouard  3275: 
                   3276:   /* Hstepm could be zero and should return the unit matrix */
                   3277:   for (i=1;i<=nlstate+ndeath;i++)
                   3278:     for (j=1;j<=nlstate+ndeath;j++){
                   3279:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3280:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3281:     }
                   3282:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3283:   for(h=1; h <=nhstepm; h++){
                   3284:     for(d=1; d <=hstepm; d++){
                   3285:       newm=savm;
                   3286:       /* Covariates have to be included here again */
                   3287:       cov[1]=1.;
1.214     brouard  3288:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3289:       cov[2]=agexact;
                   3290:       if(nagesqr==1)
1.227     brouard  3291:        cov[3]= agexact*agexact;
1.235     brouard  3292:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3293:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3294:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3295:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3296:       }
                   3297:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3298:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3299:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3300:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3301:       }
                   3302:       for (k=1; k<=cptcovage;k++){
                   3303:        if(Dummy[Tvar[Tage[k]]]){
                   3304:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3305:        } else{
                   3306:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3307:        }
                   3308:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3309:       }
                   3310:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3311:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3312:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3313:       }
                   3314:       /* for (k=1; k<=cptcovn;k++)  */
                   3315:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3316:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3317:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3318:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3319:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3320:       
                   3321:       
1.126     brouard  3322:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3323:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3324:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3325:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3326:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3327:       /* if((int)age == 70){ */
                   3328:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3329:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3330:       /*         printf("%d pmmij ",i); */
                   3331:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3332:       /*           printf("%f ",pmmij[i][j]); */
                   3333:       /*         } */
                   3334:       /*         printf(" oldm "); */
                   3335:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3336:       /*           printf("%f ",oldm[i][j]); */
                   3337:       /*         } */
                   3338:       /*         printf("\n"); */
                   3339:       /*       } */
                   3340:       /* } */
1.126     brouard  3341:       savm=oldm;
                   3342:       oldm=newm;
                   3343:     }
                   3344:     for(i=1; i<=nlstate+ndeath; i++)
                   3345:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3346:        po[i][j][h]=newm[i][j];
                   3347:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3348:       }
1.128     brouard  3349:     /*printf("h=%d ",h);*/
1.126     brouard  3350:   } /* end h */
1.267     brouard  3351:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3352:   return po;
                   3353: }
                   3354: 
1.217     brouard  3355: /************* Higher Back Matrix Product ***************/
1.218     brouard  3356: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3357: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3358: {
1.266     brouard  3359:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3360:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3361:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3362:      nhstepm*hstepm matrices.
                   3363:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3364:      (typically every 2 years instead of every month which is too big
1.217     brouard  3365:      for the memory).
1.218     brouard  3366:      Model is determined by parameters x and covariates have to be
1.266     brouard  3367:      included manually here. Then we use a call to bmij(x and cov)
                   3368:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3369:   */
1.217     brouard  3370: 
                   3371:   int i, j, d, h, k;
1.266     brouard  3372:   double **out, cov[NCOVMAX+1], **bmij();
                   3373:   double **newm, ***newmm;
1.217     brouard  3374:   double agexact;
                   3375:   double agebegin, ageend;
1.222     brouard  3376:   double **oldm, **savm;
1.217     brouard  3377: 
1.266     brouard  3378:   newmm=po; /* To be saved */
                   3379:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3380:   /* Hstepm could be zero and should return the unit matrix */
                   3381:   for (i=1;i<=nlstate+ndeath;i++)
                   3382:     for (j=1;j<=nlstate+ndeath;j++){
                   3383:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3384:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3385:     }
                   3386:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3387:   for(h=1; h <=nhstepm; h++){
                   3388:     for(d=1; d <=hstepm; d++){
                   3389:       newm=savm;
                   3390:       /* Covariates have to be included here again */
                   3391:       cov[1]=1.;
1.271     brouard  3392:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3393:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3394:       cov[2]=agexact;
                   3395:       if(nagesqr==1)
1.222     brouard  3396:        cov[3]= agexact*agexact;
1.266     brouard  3397:       for (k=1; k<=cptcovn;k++){
                   3398:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3399:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3400:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3401:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3402:       }
1.267     brouard  3403:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3404:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3405:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3406:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3407:       }
                   3408:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3409:        if(Dummy[Tvar[Tage[k]]]){
                   3410:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3411:        } else{
                   3412:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3413:        }
                   3414:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3415:       }
                   3416:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3417:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3418:       }                        
1.217     brouard  3419:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3420:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3421: 
1.218     brouard  3422:       /* Careful transposed matrix */
1.266     brouard  3423:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3424:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3425:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3426:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3427:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3428:       /* if((int)age == 70){ */
                   3429:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3430:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3431:       /*         printf("%d pmmij ",i); */
                   3432:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3433:       /*           printf("%f ",pmmij[i][j]); */
                   3434:       /*         } */
                   3435:       /*         printf(" oldm "); */
                   3436:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3437:       /*           printf("%f ",oldm[i][j]); */
                   3438:       /*         } */
                   3439:       /*         printf("\n"); */
                   3440:       /*       } */
                   3441:       /* } */
                   3442:       savm=oldm;
                   3443:       oldm=newm;
                   3444:     }
                   3445:     for(i=1; i<=nlstate+ndeath; i++)
                   3446:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3447:        po[i][j][h]=newm[i][j];
1.268     brouard  3448:        /* if(h==nhstepm) */
                   3449:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3450:       }
1.268     brouard  3451:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3452:   } /* end h */
1.268     brouard  3453:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3454:   return po;
                   3455: }
                   3456: 
                   3457: 
1.162     brouard  3458: #ifdef NLOPT
                   3459:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3460:   double fret;
                   3461:   double *xt;
                   3462:   int j;
                   3463:   myfunc_data *d2 = (myfunc_data *) pd;
                   3464: /* xt = (p1-1); */
                   3465:   xt=vector(1,n); 
                   3466:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3467: 
                   3468:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3469:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3470:   printf("Function = %.12lf ",fret);
                   3471:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3472:   printf("\n");
                   3473:  free_vector(xt,1,n);
                   3474:   return fret;
                   3475: }
                   3476: #endif
1.126     brouard  3477: 
                   3478: /*************** log-likelihood *************/
                   3479: double func( double *x)
                   3480: {
1.226     brouard  3481:   int i, ii, j, k, mi, d, kk;
                   3482:   int ioffset=0;
                   3483:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3484:   double **out;
                   3485:   double lli; /* Individual log likelihood */
                   3486:   int s1, s2;
1.228     brouard  3487:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3488:   double bbh, survp;
                   3489:   long ipmx;
                   3490:   double agexact;
                   3491:   /*extern weight */
                   3492:   /* We are differentiating ll according to initial status */
                   3493:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3494:   /*for(i=1;i<imx;i++) 
                   3495:     printf(" %d\n",s[4][i]);
                   3496:   */
1.162     brouard  3497: 
1.226     brouard  3498:   ++countcallfunc;
1.162     brouard  3499: 
1.226     brouard  3500:   cov[1]=1.;
1.126     brouard  3501: 
1.226     brouard  3502:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3503:   ioffset=0;
1.226     brouard  3504:   if(mle==1){
                   3505:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3506:       /* Computes the values of the ncovmodel covariates of the model
                   3507:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3508:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3509:         to be observed in j being in i according to the model.
                   3510:       */
1.243     brouard  3511:       ioffset=2+nagesqr ;
1.233     brouard  3512:    /* Fixed */
1.234     brouard  3513:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3514:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3515:       }
1.226     brouard  3516:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3517:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3518:         has been calculated etc */
                   3519:       /* For an individual i, wav[i] gives the number of effective waves */
                   3520:       /* We compute the contribution to Likelihood of each effective transition
                   3521:         mw[mi][i] is real wave of the mi th effectve wave */
                   3522:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3523:         s2=s[mw[mi+1][i]][i];
                   3524:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3525:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3526:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3527:       */
                   3528:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3529:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3530:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3531:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3532:        }
                   3533:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3534:          for (j=1;j<=nlstate+ndeath;j++){
                   3535:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3536:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3537:          }
                   3538:        for(d=0; d<dh[mi][i]; d++){
                   3539:          newm=savm;
                   3540:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3541:          cov[2]=agexact;
                   3542:          if(nagesqr==1)
                   3543:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3544:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3545:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3546:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3547:          else
                   3548:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3549:          }
                   3550:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3551:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3552:          savm=oldm;
                   3553:          oldm=newm;
                   3554:        } /* end mult */
                   3555:        
                   3556:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3557:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3558:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3559:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3560:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3561:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3562:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3563:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3564:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3565:                                 * -stepm/2 to stepm/2 .
                   3566:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3567:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3568:                                 */
1.234     brouard  3569:        s1=s[mw[mi][i]][i];
                   3570:        s2=s[mw[mi+1][i]][i];
                   3571:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3572:        /* bias bh is positive if real duration
                   3573:         * is higher than the multiple of stepm and negative otherwise.
                   3574:         */
                   3575:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3576:        if( s2 > nlstate){ 
                   3577:          /* i.e. if s2 is a death state and if the date of death is known 
                   3578:             then the contribution to the likelihood is the probability to 
                   3579:             die between last step unit time and current  step unit time, 
                   3580:             which is also equal to probability to die before dh 
                   3581:             minus probability to die before dh-stepm . 
                   3582:             In version up to 0.92 likelihood was computed
                   3583:             as if date of death was unknown. Death was treated as any other
                   3584:             health state: the date of the interview describes the actual state
                   3585:             and not the date of a change in health state. The former idea was
                   3586:             to consider that at each interview the state was recorded
                   3587:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3588:             introduced the exact date of death then we should have modified
                   3589:             the contribution of an exact death to the likelihood. This new
                   3590:             contribution is smaller and very dependent of the step unit
                   3591:             stepm. It is no more the probability to die between last interview
                   3592:             and month of death but the probability to survive from last
                   3593:             interview up to one month before death multiplied by the
                   3594:             probability to die within a month. Thanks to Chris
                   3595:             Jackson for correcting this bug.  Former versions increased
                   3596:             mortality artificially. The bad side is that we add another loop
                   3597:             which slows down the processing. The difference can be up to 10%
                   3598:             lower mortality.
                   3599:          */
                   3600:          /* If, at the beginning of the maximization mostly, the
                   3601:             cumulative probability or probability to be dead is
                   3602:             constant (ie = 1) over time d, the difference is equal to
                   3603:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3604:             s1 at precedent wave, to be dead a month before current
                   3605:             wave is equal to probability, being at state s1 at
                   3606:             precedent wave, to be dead at mont of the current
                   3607:             wave. Then the observed probability (that this person died)
                   3608:             is null according to current estimated parameter. In fact,
                   3609:             it should be very low but not zero otherwise the log go to
                   3610:             infinity.
                   3611:          */
1.183     brouard  3612: /* #ifdef INFINITYORIGINAL */
                   3613: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3614: /* #else */
                   3615: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3616: /*         lli=log(mytinydouble); */
                   3617: /*       else */
                   3618: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3619: /* #endif */
1.226     brouard  3620:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3621:          
1.226     brouard  3622:        } else if  ( s2==-1 ) { /* alive */
                   3623:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3624:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3625:          /*survp += out[s1][j]; */
                   3626:          lli= log(survp);
                   3627:        }
                   3628:        else if  (s2==-4) { 
                   3629:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3630:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3631:          lli= log(survp); 
                   3632:        } 
                   3633:        else if  (s2==-5) { 
                   3634:          for (j=1,survp=0. ; j<=2; j++)  
                   3635:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3636:          lli= log(survp); 
                   3637:        } 
                   3638:        else{
                   3639:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3640:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3641:        } 
                   3642:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3643:        /*if(lli ==000.0)*/
                   3644:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3645:        ipmx +=1;
                   3646:        sw += weight[i];
                   3647:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3648:        /* if (lli < log(mytinydouble)){ */
                   3649:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3650:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3651:        /* } */
                   3652:       } /* end of wave */
                   3653:     } /* end of individual */
                   3654:   }  else if(mle==2){
                   3655:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3656:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3657:       for(mi=1; mi<= wav[i]-1; mi++){
                   3658:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3659:          for (j=1;j<=nlstate+ndeath;j++){
                   3660:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3661:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3662:          }
                   3663:        for(d=0; d<=dh[mi][i]; d++){
                   3664:          newm=savm;
                   3665:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3666:          cov[2]=agexact;
                   3667:          if(nagesqr==1)
                   3668:            cov[3]= agexact*agexact;
                   3669:          for (kk=1; kk<=cptcovage;kk++) {
                   3670:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3671:          }
                   3672:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3673:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3674:          savm=oldm;
                   3675:          oldm=newm;
                   3676:        } /* end mult */
                   3677:       
                   3678:        s1=s[mw[mi][i]][i];
                   3679:        s2=s[mw[mi+1][i]][i];
                   3680:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3681:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3682:        ipmx +=1;
                   3683:        sw += weight[i];
                   3684:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3685:       } /* end of wave */
                   3686:     } /* end of individual */
                   3687:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3688:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3689:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3690:       for(mi=1; mi<= wav[i]-1; mi++){
                   3691:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3692:          for (j=1;j<=nlstate+ndeath;j++){
                   3693:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3694:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3695:          }
                   3696:        for(d=0; d<dh[mi][i]; d++){
                   3697:          newm=savm;
                   3698:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3699:          cov[2]=agexact;
                   3700:          if(nagesqr==1)
                   3701:            cov[3]= agexact*agexact;
                   3702:          for (kk=1; kk<=cptcovage;kk++) {
                   3703:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3704:          }
                   3705:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3706:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3707:          savm=oldm;
                   3708:          oldm=newm;
                   3709:        } /* end mult */
                   3710:       
                   3711:        s1=s[mw[mi][i]][i];
                   3712:        s2=s[mw[mi+1][i]][i];
                   3713:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3714:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3715:        ipmx +=1;
                   3716:        sw += weight[i];
                   3717:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3718:       } /* end of wave */
                   3719:     } /* end of individual */
                   3720:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3721:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3722:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3723:       for(mi=1; mi<= wav[i]-1; mi++){
                   3724:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3725:          for (j=1;j<=nlstate+ndeath;j++){
                   3726:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3727:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3728:          }
                   3729:        for(d=0; d<dh[mi][i]; d++){
                   3730:          newm=savm;
                   3731:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3732:          cov[2]=agexact;
                   3733:          if(nagesqr==1)
                   3734:            cov[3]= agexact*agexact;
                   3735:          for (kk=1; kk<=cptcovage;kk++) {
                   3736:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3737:          }
1.126     brouard  3738:        
1.226     brouard  3739:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3740:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3741:          savm=oldm;
                   3742:          oldm=newm;
                   3743:        } /* end mult */
                   3744:       
                   3745:        s1=s[mw[mi][i]][i];
                   3746:        s2=s[mw[mi+1][i]][i];
                   3747:        if( s2 > nlstate){ 
                   3748:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3749:        } else if  ( s2==-1 ) { /* alive */
                   3750:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3751:            survp += out[s1][j];
                   3752:          lli= log(survp);
                   3753:        }else{
                   3754:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3755:        }
                   3756:        ipmx +=1;
                   3757:        sw += weight[i];
                   3758:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3759: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3760:       } /* end of wave */
                   3761:     } /* end of individual */
                   3762:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3763:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3764:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3765:       for(mi=1; mi<= wav[i]-1; mi++){
                   3766:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3767:          for (j=1;j<=nlstate+ndeath;j++){
                   3768:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3769:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3770:          }
                   3771:        for(d=0; d<dh[mi][i]; d++){
                   3772:          newm=savm;
                   3773:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3774:          cov[2]=agexact;
                   3775:          if(nagesqr==1)
                   3776:            cov[3]= agexact*agexact;
                   3777:          for (kk=1; kk<=cptcovage;kk++) {
                   3778:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3779:          }
1.126     brouard  3780:        
1.226     brouard  3781:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3782:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3783:          savm=oldm;
                   3784:          oldm=newm;
                   3785:        } /* end mult */
                   3786:       
                   3787:        s1=s[mw[mi][i]][i];
                   3788:        s2=s[mw[mi+1][i]][i];
                   3789:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3790:        ipmx +=1;
                   3791:        sw += weight[i];
                   3792:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3793:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3794:       } /* end of wave */
                   3795:     } /* end of individual */
                   3796:   } /* End of if */
                   3797:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3798:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3799:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3800:   return -l;
1.126     brouard  3801: }
                   3802: 
                   3803: /*************** log-likelihood *************/
                   3804: double funcone( double *x)
                   3805: {
1.228     brouard  3806:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3807:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3808:   int ioffset=0;
1.131     brouard  3809:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3810:   double **out;
                   3811:   double lli; /* Individual log likelihood */
                   3812:   double llt;
                   3813:   int s1, s2;
1.228     brouard  3814:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3815: 
1.126     brouard  3816:   double bbh, survp;
1.187     brouard  3817:   double agexact;
1.214     brouard  3818:   double agebegin, ageend;
1.126     brouard  3819:   /*extern weight */
                   3820:   /* We are differentiating ll according to initial status */
                   3821:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3822:   /*for(i=1;i<imx;i++) 
                   3823:     printf(" %d\n",s[4][i]);
                   3824:   */
                   3825:   cov[1]=1.;
                   3826: 
                   3827:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3828:   ioffset=0;
                   3829:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3830:     /* ioffset=2+nagesqr+cptcovage; */
                   3831:     ioffset=2+nagesqr;
1.232     brouard  3832:     /* Fixed */
1.224     brouard  3833:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3834:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
                   3835:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3836:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3837: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3838: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3839: /*    cov[2+6]=covar[2][i]; V2  */
                   3840: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3841: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3842: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3843: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3844: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3845: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3846:     }
1.232     brouard  3847:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3848:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3849:     /* } */
1.231     brouard  3850:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3851:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3852:     /* } */
1.225     brouard  3853:     
1.233     brouard  3854: 
                   3855:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3856:     /* Wave varying (but not age varying) */
                   3857:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3858:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3859:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3860:       }
1.232     brouard  3861:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3862:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3863:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3864:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3865:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3866:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3867:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3868:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3869:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3870:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3871:       /* } */
1.126     brouard  3872:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3873:        for (j=1;j<=nlstate+ndeath;j++){
                   3874:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3875:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3876:        }
1.214     brouard  3877:       
                   3878:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3879:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3880:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3881:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3882:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3883:          and mw[mi+1][i]. dh depends on stepm.*/
                   3884:        newm=savm;
1.247     brouard  3885:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3886:        cov[2]=agexact;
                   3887:        if(nagesqr==1)
                   3888:          cov[3]= agexact*agexact;
                   3889:        for (kk=1; kk<=cptcovage;kk++) {
                   3890:          if(!FixedV[Tvar[Tage[kk]]])
                   3891:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3892:          else
                   3893:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3894:        }
                   3895:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3896:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3897:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3898:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3899:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3900:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3901:        savm=oldm;
                   3902:        oldm=newm;
1.126     brouard  3903:       } /* end mult */
                   3904:       
                   3905:       s1=s[mw[mi][i]][i];
                   3906:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3907:       /* if(s2==-1){ */
1.268     brouard  3908:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3909:       /*       /\* exit(1); *\/ */
                   3910:       /* } */
1.126     brouard  3911:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3912:       /* bias is positive if real duration
                   3913:        * is higher than the multiple of stepm and negative otherwise.
                   3914:        */
                   3915:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3916:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3917:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3918:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3919:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3920:        lli= log(survp);
1.126     brouard  3921:       }else if (mle==1){
1.242     brouard  3922:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3923:       } else if(mle==2){
1.242     brouard  3924:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3925:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3926:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3927:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3928:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3929:       } else{  /* mle=0 back to 1 */
1.242     brouard  3930:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3931:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3932:       } /* End of if */
                   3933:       ipmx +=1;
                   3934:       sw += weight[i];
                   3935:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3936:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3937:       if(globpr){
1.246     brouard  3938:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3939:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3940:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3941:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3942:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3943:          llt +=ll[k]*gipmx/gsw;
                   3944:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3945:        }
                   3946:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3947:       }
1.232     brouard  3948:        } /* end of wave */
                   3949: } /* end of individual */
                   3950: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3951: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3952: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3953: if(globpr==0){ /* First time we count the contributions and weights */
                   3954:        gipmx=ipmx;
                   3955:        gsw=sw;
                   3956: }
                   3957: return -l;
1.126     brouard  3958: }
                   3959: 
                   3960: 
                   3961: /*************** function likelione ***********/
1.292     brouard  3962: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  3963: {
                   3964:   /* This routine should help understanding what is done with 
                   3965:      the selection of individuals/waves and
                   3966:      to check the exact contribution to the likelihood.
                   3967:      Plotting could be done.
                   3968:    */
                   3969:   int k;
                   3970: 
                   3971:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3972:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3973:     strcat(fileresilk,fileresu);
1.126     brouard  3974:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3975:       printf("Problem with resultfile: %s\n", fileresilk);
                   3976:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3977:     }
1.214     brouard  3978:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3979:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3980:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3981:     for(k=1; k<=nlstate; k++) 
                   3982:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3983:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3984:   }
                   3985: 
1.292     brouard  3986:   *fretone=(*func)(p);
1.126     brouard  3987:   if(*globpri !=0){
                   3988:     fclose(ficresilk);
1.205     brouard  3989:     if (mle ==0)
                   3990:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   3991:     else if(mle >=1)
                   3992:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   3993:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  3994:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  3995:       
                   3996:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  3997:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  3998: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   3999:     }
1.207     brouard  4000:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  4001: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4002:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  4003: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4004:     fflush(fichtm);
1.205     brouard  4005:   }
1.126     brouard  4006:   return;
                   4007: }
                   4008: 
                   4009: 
                   4010: /*********** Maximum Likelihood Estimation ***************/
                   4011: 
                   4012: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   4013: {
1.165     brouard  4014:   int i,j, iter=0;
1.126     brouard  4015:   double **xi;
                   4016:   double fret;
                   4017:   double fretone; /* Only one call to likelihood */
                   4018:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  4019: 
                   4020: #ifdef NLOPT
                   4021:   int creturn;
                   4022:   nlopt_opt opt;
                   4023:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   4024:   double *lb;
                   4025:   double minf; /* the minimum objective value, upon return */
                   4026:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   4027:   myfunc_data dinst, *d = &dinst;
                   4028: #endif
                   4029: 
                   4030: 
1.126     brouard  4031:   xi=matrix(1,npar,1,npar);
                   4032:   for (i=1;i<=npar;i++)
                   4033:     for (j=1;j<=npar;j++)
                   4034:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   4035:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  4036:   strcpy(filerespow,"POW_"); 
1.126     brouard  4037:   strcat(filerespow,fileres);
                   4038:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   4039:     printf("Problem with resultfile: %s\n", filerespow);
                   4040:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   4041:   }
                   4042:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   4043:   for (i=1;i<=nlstate;i++)
                   4044:     for(j=1;j<=nlstate+ndeath;j++)
                   4045:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   4046:   fprintf(ficrespow,"\n");
1.162     brouard  4047: #ifdef POWELL
1.126     brouard  4048:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  4049: #endif
1.126     brouard  4050: 
1.162     brouard  4051: #ifdef NLOPT
                   4052: #ifdef NEWUOA
                   4053:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   4054: #else
                   4055:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   4056: #endif
                   4057:   lb=vector(0,npar-1);
                   4058:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   4059:   nlopt_set_lower_bounds(opt, lb);
                   4060:   nlopt_set_initial_step1(opt, 0.1);
                   4061:   
                   4062:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   4063:   d->function = func;
                   4064:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   4065:   nlopt_set_min_objective(opt, myfunc, d);
                   4066:   nlopt_set_xtol_rel(opt, ftol);
                   4067:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4068:     printf("nlopt failed! %d\n",creturn); 
                   4069:   }
                   4070:   else {
                   4071:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4072:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4073:     iter=1; /* not equal */
                   4074:   }
                   4075:   nlopt_destroy(opt);
                   4076: #endif
1.126     brouard  4077:   free_matrix(xi,1,npar,1,npar);
                   4078:   fclose(ficrespow);
1.203     brouard  4079:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4080:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4081:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4082: 
                   4083: }
                   4084: 
                   4085: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4086: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4087: {
                   4088:   double  **a,**y,*x,pd;
1.203     brouard  4089:   /* double **hess; */
1.164     brouard  4090:   int i, j;
1.126     brouard  4091:   int *indx;
                   4092: 
                   4093:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4094:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4095:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4096:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4097:   double gompertz(double p[]);
1.203     brouard  4098:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4099: 
                   4100:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4101:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4102:   for (i=1;i<=npar;i++){
1.203     brouard  4103:     printf("%d-",i);fflush(stdout);
                   4104:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4105:    
                   4106:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4107:     
                   4108:     /*  printf(" %f ",p[i]);
                   4109:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4110:   }
                   4111:   
                   4112:   for (i=1;i<=npar;i++) {
                   4113:     for (j=1;j<=npar;j++)  {
                   4114:       if (j>i) { 
1.203     brouard  4115:        printf(".%d-%d",i,j);fflush(stdout);
                   4116:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4117:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4118:        
                   4119:        hess[j][i]=hess[i][j];    
                   4120:        /*printf(" %lf ",hess[i][j]);*/
                   4121:       }
                   4122:     }
                   4123:   }
                   4124:   printf("\n");
                   4125:   fprintf(ficlog,"\n");
                   4126: 
                   4127:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4128:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4129:   
                   4130:   a=matrix(1,npar,1,npar);
                   4131:   y=matrix(1,npar,1,npar);
                   4132:   x=vector(1,npar);
                   4133:   indx=ivector(1,npar);
                   4134:   for (i=1;i<=npar;i++)
                   4135:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4136:   ludcmp(a,npar,indx,&pd);
                   4137: 
                   4138:   for (j=1;j<=npar;j++) {
                   4139:     for (i=1;i<=npar;i++) x[i]=0;
                   4140:     x[j]=1;
                   4141:     lubksb(a,npar,indx,x);
                   4142:     for (i=1;i<=npar;i++){ 
                   4143:       matcov[i][j]=x[i];
                   4144:     }
                   4145:   }
                   4146: 
                   4147:   printf("\n#Hessian matrix#\n");
                   4148:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4149:   for (i=1;i<=npar;i++) { 
                   4150:     for (j=1;j<=npar;j++) { 
1.203     brouard  4151:       printf("%.6e ",hess[i][j]);
                   4152:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4153:     }
                   4154:     printf("\n");
                   4155:     fprintf(ficlog,"\n");
                   4156:   }
                   4157: 
1.203     brouard  4158:   /* printf("\n#Covariance matrix#\n"); */
                   4159:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4160:   /* for (i=1;i<=npar;i++) {  */
                   4161:   /*   for (j=1;j<=npar;j++) {  */
                   4162:   /*     printf("%.6e ",matcov[i][j]); */
                   4163:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4164:   /*   } */
                   4165:   /*   printf("\n"); */
                   4166:   /*   fprintf(ficlog,"\n"); */
                   4167:   /* } */
                   4168: 
1.126     brouard  4169:   /* Recompute Inverse */
1.203     brouard  4170:   /* for (i=1;i<=npar;i++) */
                   4171:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4172:   /* ludcmp(a,npar,indx,&pd); */
                   4173: 
                   4174:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4175: 
                   4176:   /* for (j=1;j<=npar;j++) { */
                   4177:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4178:   /*   x[j]=1; */
                   4179:   /*   lubksb(a,npar,indx,x); */
                   4180:   /*   for (i=1;i<=npar;i++){  */
                   4181:   /*     y[i][j]=x[i]; */
                   4182:   /*     printf("%.3e ",y[i][j]); */
                   4183:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4184:   /*   } */
                   4185:   /*   printf("\n"); */
                   4186:   /*   fprintf(ficlog,"\n"); */
                   4187:   /* } */
                   4188: 
                   4189:   /* Verifying the inverse matrix */
                   4190: #ifdef DEBUGHESS
                   4191:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4192: 
1.203     brouard  4193:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4194:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4195: 
                   4196:   for (j=1;j<=npar;j++) {
                   4197:     for (i=1;i<=npar;i++){ 
1.203     brouard  4198:       printf("%.2f ",y[i][j]);
                   4199:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4200:     }
                   4201:     printf("\n");
                   4202:     fprintf(ficlog,"\n");
                   4203:   }
1.203     brouard  4204: #endif
1.126     brouard  4205: 
                   4206:   free_matrix(a,1,npar,1,npar);
                   4207:   free_matrix(y,1,npar,1,npar);
                   4208:   free_vector(x,1,npar);
                   4209:   free_ivector(indx,1,npar);
1.203     brouard  4210:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4211: 
                   4212: 
                   4213: }
                   4214: 
                   4215: /*************** hessian matrix ****************/
                   4216: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4217: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4218:   int i;
                   4219:   int l=1, lmax=20;
1.203     brouard  4220:   double k1,k2, res, fx;
1.132     brouard  4221:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4222:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4223:   int k=0,kmax=10;
                   4224:   double l1;
                   4225: 
                   4226:   fx=func(x);
                   4227:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4228:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4229:     l1=pow(10,l);
                   4230:     delts=delt;
                   4231:     for(k=1 ; k <kmax; k=k+1){
                   4232:       delt = delta*(l1*k);
                   4233:       p2[theta]=x[theta] +delt;
1.145     brouard  4234:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4235:       p2[theta]=x[theta]-delt;
                   4236:       k2=func(p2)-fx;
                   4237:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4238:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4239:       
1.203     brouard  4240: #ifdef DEBUGHESSII
1.126     brouard  4241:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4242:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4243: #endif
                   4244:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4245:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4246:        k=kmax;
                   4247:       }
                   4248:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4249:        k=kmax; l=lmax*10;
1.126     brouard  4250:       }
                   4251:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4252:        delts=delt;
                   4253:       }
1.203     brouard  4254:     } /* End loop k */
1.126     brouard  4255:   }
                   4256:   delti[theta]=delts;
                   4257:   return res; 
                   4258:   
                   4259: }
                   4260: 
1.203     brouard  4261: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4262: {
                   4263:   int i;
1.164     brouard  4264:   int l=1, lmax=20;
1.126     brouard  4265:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4266:   double p2[MAXPARM+1];
1.203     brouard  4267:   int k, kmax=1;
                   4268:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4269: 
                   4270:   int firstime=0;
1.203     brouard  4271:   
1.126     brouard  4272:   fx=func(x);
1.203     brouard  4273:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4274:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4275:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4276:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4277:     k1=func(p2)-fx;
                   4278:   
1.203     brouard  4279:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4280:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4281:     k2=func(p2)-fx;
                   4282:   
1.203     brouard  4283:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4284:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4285:     k3=func(p2)-fx;
                   4286:   
1.203     brouard  4287:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4288:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4289:     k4=func(p2)-fx;
1.203     brouard  4290:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4291:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4292:       firstime=1;
1.203     brouard  4293:       kmax=kmax+10;
1.208     brouard  4294:     }
                   4295:     if(kmax >=10 || firstime ==1){
1.246     brouard  4296:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4297:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4298:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4299:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4300:     }
                   4301: #ifdef DEBUGHESSIJ
                   4302:     v1=hess[thetai][thetai];
                   4303:     v2=hess[thetaj][thetaj];
                   4304:     cv12=res;
                   4305:     /* Computing eigen value of Hessian matrix */
                   4306:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4307:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4308:     if ((lc2 <0) || (lc1 <0) ){
                   4309:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4310:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4311:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4312:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4313:     }
1.126     brouard  4314: #endif
                   4315:   }
                   4316:   return res;
                   4317: }
                   4318: 
1.203     brouard  4319:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4320: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4321: /* { */
                   4322: /*   int i; */
                   4323: /*   int l=1, lmax=20; */
                   4324: /*   double k1,k2,k3,k4,res,fx; */
                   4325: /*   double p2[MAXPARM+1]; */
                   4326: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4327: /*   int k=0,kmax=10; */
                   4328: /*   double l1; */
                   4329:   
                   4330: /*   fx=func(x); */
                   4331: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4332: /*     l1=pow(10,l); */
                   4333: /*     delts=delt; */
                   4334: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4335: /*       delt = delti*(l1*k); */
                   4336: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4337: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4338: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4339: /*       k1=func(p2)-fx; */
                   4340:       
                   4341: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4342: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4343: /*       k2=func(p2)-fx; */
                   4344:       
                   4345: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4346: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4347: /*       k3=func(p2)-fx; */
                   4348:       
                   4349: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4350: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4351: /*       k4=func(p2)-fx; */
                   4352: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4353: /* #ifdef DEBUGHESSIJ */
                   4354: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4355: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4356: /* #endif */
                   4357: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4358: /*     k=kmax; */
                   4359: /*       } */
                   4360: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4361: /*     k=kmax; l=lmax*10; */
                   4362: /*       } */
                   4363: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4364: /*     delts=delt; */
                   4365: /*       } */
                   4366: /*     } /\* End loop k *\/ */
                   4367: /*   } */
                   4368: /*   delti[theta]=delts; */
                   4369: /*   return res;  */
                   4370: /* } */
                   4371: 
                   4372: 
1.126     brouard  4373: /************** Inverse of matrix **************/
                   4374: void ludcmp(double **a, int n, int *indx, double *d) 
                   4375: { 
                   4376:   int i,imax,j,k; 
                   4377:   double big,dum,sum,temp; 
                   4378:   double *vv; 
                   4379:  
                   4380:   vv=vector(1,n); 
                   4381:   *d=1.0; 
                   4382:   for (i=1;i<=n;i++) { 
                   4383:     big=0.0; 
                   4384:     for (j=1;j<=n;j++) 
                   4385:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4386:     if (big == 0.0){
                   4387:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4388:       for (j=1;j<=n;j++) {
                   4389:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4390:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4391:       }
                   4392:       fflush(ficlog);
                   4393:       fclose(ficlog);
                   4394:       nrerror("Singular matrix in routine ludcmp"); 
                   4395:     }
1.126     brouard  4396:     vv[i]=1.0/big; 
                   4397:   } 
                   4398:   for (j=1;j<=n;j++) { 
                   4399:     for (i=1;i<j;i++) { 
                   4400:       sum=a[i][j]; 
                   4401:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4402:       a[i][j]=sum; 
                   4403:     } 
                   4404:     big=0.0; 
                   4405:     for (i=j;i<=n;i++) { 
                   4406:       sum=a[i][j]; 
                   4407:       for (k=1;k<j;k++) 
                   4408:        sum -= a[i][k]*a[k][j]; 
                   4409:       a[i][j]=sum; 
                   4410:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4411:        big=dum; 
                   4412:        imax=i; 
                   4413:       } 
                   4414:     } 
                   4415:     if (j != imax) { 
                   4416:       for (k=1;k<=n;k++) { 
                   4417:        dum=a[imax][k]; 
                   4418:        a[imax][k]=a[j][k]; 
                   4419:        a[j][k]=dum; 
                   4420:       } 
                   4421:       *d = -(*d); 
                   4422:       vv[imax]=vv[j]; 
                   4423:     } 
                   4424:     indx[j]=imax; 
                   4425:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4426:     if (j != n) { 
                   4427:       dum=1.0/(a[j][j]); 
                   4428:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4429:     } 
                   4430:   } 
                   4431:   free_vector(vv,1,n);  /* Doesn't work */
                   4432: ;
                   4433: } 
                   4434: 
                   4435: void lubksb(double **a, int n, int *indx, double b[]) 
                   4436: { 
                   4437:   int i,ii=0,ip,j; 
                   4438:   double sum; 
                   4439:  
                   4440:   for (i=1;i<=n;i++) { 
                   4441:     ip=indx[i]; 
                   4442:     sum=b[ip]; 
                   4443:     b[ip]=b[i]; 
                   4444:     if (ii) 
                   4445:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4446:     else if (sum) ii=i; 
                   4447:     b[i]=sum; 
                   4448:   } 
                   4449:   for (i=n;i>=1;i--) { 
                   4450:     sum=b[i]; 
                   4451:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4452:     b[i]=sum/a[i][i]; 
                   4453:   } 
                   4454: } 
                   4455: 
                   4456: void pstamp(FILE *fichier)
                   4457: {
1.196     brouard  4458:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4459: }
                   4460: 
1.297     brouard  4461: void date2dmy(double date,double *day, double *month, double *year){
                   4462:   double yp=0., yp1=0., yp2=0.;
                   4463:   
                   4464:   yp1=modf(date,&yp);/* extracts integral of date in yp  and
                   4465:                        fractional in yp1 */
                   4466:   *year=yp;
                   4467:   yp2=modf((yp1*12),&yp);
                   4468:   *month=yp;
                   4469:   yp1=modf((yp2*30.5),&yp);
                   4470:   *day=yp;
                   4471:   if(*day==0) *day=1;
                   4472:   if(*month==0) *month=1;
                   4473: }
                   4474: 
1.253     brouard  4475: 
                   4476: 
1.126     brouard  4477: /************ Frequencies ********************/
1.251     brouard  4478: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4479:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4480:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4481: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4482:   
1.265     brouard  4483:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4484:   int iind=0, iage=0;
                   4485:   int mi; /* Effective wave */
                   4486:   int first;
                   4487:   double ***freq; /* Frequencies */
1.268     brouard  4488:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4489:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4490:   double *meanq, *stdq, *idq;
1.226     brouard  4491:   double **meanqt;
                   4492:   double *pp, **prop, *posprop, *pospropt;
                   4493:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4494:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4495:   double agebegin, ageend;
                   4496:     
                   4497:   pp=vector(1,nlstate);
1.251     brouard  4498:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4499:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4500:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4501:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4502:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4503:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4504:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4505:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4506:   strcpy(fileresp,"P_");
                   4507:   strcat(fileresp,fileresu);
                   4508:   /*strcat(fileresphtm,fileresu);*/
                   4509:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4510:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4511:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4512:     exit(0);
                   4513:   }
1.240     brouard  4514:   
1.226     brouard  4515:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4516:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4517:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4518:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4519:     fflush(ficlog);
                   4520:     exit(70); 
                   4521:   }
                   4522:   else{
                   4523:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4524: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4525: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4526:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4527:   }
1.237     brouard  4528:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4529:   
1.226     brouard  4530:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4531:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4532:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4533:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4534:     fflush(ficlog);
                   4535:     exit(70); 
1.240     brouard  4536:   } else{
1.226     brouard  4537:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4538: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4539: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4540:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4541:   }
1.240     brouard  4542:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4543:   
1.253     brouard  4544:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4545:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4546:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4547:   j1=0;
1.126     brouard  4548:   
1.227     brouard  4549:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4550:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4551:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4552:   
                   4553:   
1.226     brouard  4554:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4555:      reference=low_education V1=0,V2=0
                   4556:      med_educ                V1=1 V2=0, 
                   4557:      high_educ               V1=0 V2=1
                   4558:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4559:   */
1.249     brouard  4560:   dateintsum=0;
                   4561:   k2cpt=0;
                   4562: 
1.253     brouard  4563:   if(cptcoveff == 0 )
1.265     brouard  4564:     nl=1;  /* Constant and age model only */
1.253     brouard  4565:   else
                   4566:     nl=2;
1.265     brouard  4567: 
                   4568:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4569:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4570:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4571:    *     freq[s1][s2][iage] =0.
                   4572:    *     Loop on iind
                   4573:    *       ++freq[s1][s2][iage] weighted
                   4574:    *     end iind
                   4575:    *     if covariate and j!0
                   4576:    *       headers Variable on one line
                   4577:    *     endif cov j!=0
                   4578:    *     header of frequency table by age
                   4579:    *     Loop on age
                   4580:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4581:    *       pos+=freq[s1][s2][iage] weighted
                   4582:    *       Loop on s1 initial state
                   4583:    *         fprintf(ficresp
                   4584:    *       end s1
                   4585:    *     end age
                   4586:    *     if j!=0 computes starting values
                   4587:    *     end compute starting values
                   4588:    *   end j1
                   4589:    * end nl 
                   4590:    */
1.253     brouard  4591:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4592:     if(nj==1)
                   4593:       j=0;  /* First pass for the constant */
1.265     brouard  4594:     else{
1.253     brouard  4595:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4596:     }
1.251     brouard  4597:     first=1;
1.265     brouard  4598:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4599:       posproptt=0.;
                   4600:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4601:        scanf("%d", i);*/
                   4602:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4603:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4604:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4605:            freq[i][s2][m]=0;
1.251     brouard  4606:       
                   4607:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4608:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4609:          prop[i][m]=0;
                   4610:        posprop[i]=0;
                   4611:        pospropt[i]=0;
                   4612:       }
1.283     brouard  4613:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4614:         idq[z1]=0.;
                   4615:         meanq[z1]=0.;
                   4616:         stdq[z1]=0.;
1.283     brouard  4617:       }
                   4618:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4619:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4620:       /*         meanqt[m][z1]=0.; */
                   4621:       /*       } */
                   4622:       /* }       */
1.251     brouard  4623:       /* dateintsum=0; */
                   4624:       /* k2cpt=0; */
                   4625:       
1.265     brouard  4626:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4627:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4628:        bool=1;
                   4629:        if(j !=0){
                   4630:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4631:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4632:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4633:                /* if(Tvaraff[z1] ==-20){ */
                   4634:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4635:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4636:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4637:                /* }else  */
                   4638:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4639:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4640:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4641:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4642:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4643:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4644:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4645:                } /* Onlyf fixed */
                   4646:              } /* end z1 */
                   4647:            } /* cptcovn > 0 */
                   4648:          } /* end any */
                   4649:        }/* end j==0 */
1.265     brouard  4650:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4651:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4652:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4653:            m=mw[mi][iind];
                   4654:            if(j!=0){
                   4655:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4656:                for (z1=1; z1<=cptcoveff; z1++) {
                   4657:                  if( Fixed[Tmodelind[z1]]==1){
                   4658:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4659:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4660:                                                                                      value is -1, we don't select. It differs from the 
                   4661:                                                                                      constant and age model which counts them. */
                   4662:                      bool=0; /* not selected */
                   4663:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4664:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4665:                      bool=0;
                   4666:                    }
                   4667:                  }
                   4668:                }
                   4669:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4670:            } /* end j==0 */
                   4671:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4672:            if(bool==1){ /*Selected */
1.251     brouard  4673:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4674:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4675:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4676:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4677:              if(m >=firstpass && m <=lastpass){
                   4678:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4679:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4680:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4681:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4682:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4683:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4684:                if (m<lastpass) {
                   4685:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4686:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4687:                  if(s[m][iind]==-1)
                   4688:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4689:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.284     brouard  4690:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean */
                   4691:                    idq[z1]=idq[z1]+weight[iind];
                   4692:                    meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4693:                    stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4694:                  }
1.251     brouard  4695:                  /* if((int)agev[m][iind] == 55) */
                   4696:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4697:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4698:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4699:                }
1.251     brouard  4700:              } /* end if between passes */  
                   4701:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4702:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4703:                k2cpt++;
                   4704:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4705:              }
1.251     brouard  4706:            }else{
                   4707:              bool=1;
                   4708:            }/* end bool 2 */
                   4709:          } /* end m */
1.284     brouard  4710:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4711:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4712:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4713:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4714:          /* } */
1.251     brouard  4715:        } /* end bool */
                   4716:       } /* end iind = 1 to imx */
                   4717:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4718:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4719:       
                   4720:       
                   4721:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4722:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4723:         pstamp(ficresp);
1.251     brouard  4724:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4725:         pstamp(ficresp);
1.251     brouard  4726:        printf( "\n#********** Variable "); 
                   4727:        fprintf(ficresp, "\n#********** Variable "); 
                   4728:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4729:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4730:        fprintf(ficlog, "\n#********** Variable "); 
                   4731:        for (z1=1; z1<=cptcoveff; z1++){
                   4732:          if(!FixedV[Tvaraff[z1]]){
                   4733:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4734:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4735:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4736:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4737:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4738:          }else{
1.251     brouard  4739:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4740:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4741:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4742:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4743:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4744:          }
                   4745:        }
                   4746:        printf( "**********\n#");
                   4747:        fprintf(ficresp, "**********\n#");
                   4748:        fprintf(ficresphtm, "**********</h3>\n");
                   4749:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4750:        fprintf(ficlog, "**********\n");
                   4751:       }
1.284     brouard  4752:       /*
                   4753:        Printing means of quantitative variables if any
                   4754:       */
                   4755:       for (z1=1; z1<= nqfveff; z1++) {
1.285     brouard  4756:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.0f individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.284     brouard  4757:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
                   4758:        if(weightopt==1){
                   4759:          printf(" Weighted mean and standard deviation of");
                   4760:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4761:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4762:        }
1.285     brouard  4763:        printf(" fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4764:        fprintf(ficlog," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
                   4765:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.0f representatives of the population : %6.3g (%6.3g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt((stdq[z1]-meanq[z1]*meanq[z1]/idq[z1])/idq[z1]));
1.284     brouard  4766:       }
                   4767:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4768:       /*       for(m=1;m<=lastpass;m++){ */
                   4769:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4770:       /*   } */
                   4771:       /* } */
1.283     brouard  4772: 
1.251     brouard  4773:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4774:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4775:         fprintf(ficresp, " Age");
                   4776:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4777:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4778:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4779:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4780:       }
1.265     brouard  4781:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4782:       fprintf(ficresphtm, "\n");
                   4783:       
                   4784:       /* Header of frequency table by age */
                   4785:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4786:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4787:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4788:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4789:          if(s2!=0 && m!=0)
                   4790:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4791:        }
1.226     brouard  4792:       }
1.251     brouard  4793:       fprintf(ficresphtmfr, "\n");
                   4794:     
                   4795:       /* For each age */
                   4796:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4797:        fprintf(ficresphtm,"<tr>");
                   4798:        if(iage==iagemax+1){
                   4799:          fprintf(ficlog,"1");
                   4800:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4801:        }else if(iage==iagemax+2){
                   4802:          fprintf(ficlog,"0");
                   4803:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4804:        }else if(iage==iagemax+3){
                   4805:          fprintf(ficlog,"Total");
                   4806:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4807:        }else{
1.240     brouard  4808:          if(first==1){
1.251     brouard  4809:            first=0;
                   4810:            printf("See log file for details...\n");
                   4811:          }
                   4812:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4813:          fprintf(ficlog,"Age %d", iage);
                   4814:        }
1.265     brouard  4815:        for(s1=1; s1 <=nlstate ; s1++){
                   4816:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4817:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4818:        }
1.265     brouard  4819:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4820:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4821:            pos += freq[s1][m][iage];
                   4822:          if(pp[s1]>=1.e-10){
1.251     brouard  4823:            if(first==1){
1.265     brouard  4824:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4825:            }
1.265     brouard  4826:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4827:          }else{
                   4828:            if(first==1)
1.265     brouard  4829:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4830:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4831:          }
                   4832:        }
                   4833:       
1.265     brouard  4834:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4835:          /* posprop[s1]=0; */
                   4836:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4837:            pp[s1] += freq[s1][m][iage];
                   4838:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4839:       
                   4840:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4841:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4842:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4843:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4844:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4845:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4846:        }
                   4847:        
                   4848:        /* Writing ficresp */
                   4849:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4850:           if( iage <= iagemax){
                   4851:            fprintf(ficresp," %d",iage);
                   4852:           }
                   4853:         }else if( nj==2){
                   4854:           if( iage <= iagemax){
                   4855:            fprintf(ficresp," %d",iage);
                   4856:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4857:           }
1.240     brouard  4858:        }
1.265     brouard  4859:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4860:          if(pos>=1.e-5){
1.251     brouard  4861:            if(first==1)
1.265     brouard  4862:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4863:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4864:          }else{
                   4865:            if(first==1)
1.265     brouard  4866:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4867:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4868:          }
                   4869:          if( iage <= iagemax){
                   4870:            if(pos>=1.e-5){
1.265     brouard  4871:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4872:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4873:               }else if( nj==2){
                   4874:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4875:               }
                   4876:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4877:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4878:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4879:            } else{
                   4880:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4881:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4882:            }
1.240     brouard  4883:          }
1.265     brouard  4884:          pospropt[s1] +=posprop[s1];
                   4885:        } /* end loop s1 */
1.251     brouard  4886:        /* pospropt=0.; */
1.265     brouard  4887:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4888:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4889:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4890:              if(first==1){
1.265     brouard  4891:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4892:              }
1.265     brouard  4893:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4894:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4895:            }
1.265     brouard  4896:            if(s1!=0 && m!=0)
                   4897:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4898:          }
1.265     brouard  4899:        } /* end loop s1 */
1.251     brouard  4900:        posproptt=0.; 
1.265     brouard  4901:        for(s1=1; s1 <=nlstate; s1++){
                   4902:          posproptt += pospropt[s1];
1.251     brouard  4903:        }
                   4904:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4905:        fprintf(ficresphtm,"</tr>\n");
                   4906:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4907:          if(iage <= iagemax)
                   4908:            fprintf(ficresp,"\n");
1.240     brouard  4909:        }
1.251     brouard  4910:        if(first==1)
                   4911:          printf("Others in log...\n");
                   4912:        fprintf(ficlog,"\n");
                   4913:       } /* end loop age iage */
1.265     brouard  4914:       
1.251     brouard  4915:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4916:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4917:        if(posproptt < 1.e-5){
1.265     brouard  4918:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4919:        }else{
1.265     brouard  4920:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4921:        }
1.226     brouard  4922:       }
1.251     brouard  4923:       fprintf(ficresphtm,"</tr>\n");
                   4924:       fprintf(ficresphtm,"</table>\n");
                   4925:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4926:       if(posproptt < 1.e-5){
1.251     brouard  4927:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4928:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4929:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4930:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4931:        invalidvarcomb[j1]=1;
1.226     brouard  4932:       }else{
1.251     brouard  4933:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4934:        invalidvarcomb[j1]=0;
1.226     brouard  4935:       }
1.251     brouard  4936:       fprintf(ficresphtmfr,"</table>\n");
                   4937:       fprintf(ficlog,"\n");
                   4938:       if(j!=0){
                   4939:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4940:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4941:          for(k=1; k <=(nlstate+ndeath); k++){
                   4942:            if (k != i) {
1.265     brouard  4943:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4944:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4945:                  if(j1==1){ /* All dummy covariates to zero */
                   4946:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4947:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4948:                    printf("%d%d ",i,k);
                   4949:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4950:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4951:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4952:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4953:                  }
1.253     brouard  4954:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4955:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4956:                    x[iage]= (double)iage;
                   4957:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4958:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4959:                  }
1.268     brouard  4960:                  /* Some are not finite, but linreg will ignore these ages */
                   4961:                  no=0;
1.253     brouard  4962:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4963:                  pstart[s1]=b;
                   4964:                  pstart[s1-1]=a;
1.252     brouard  4965:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4966:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4967:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4968:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4969:                  printf("%d%d ",i,k);
                   4970:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4971:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4972:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4973:                  ;
                   4974:                }
                   4975:                /* printf("%12.7f )", param[i][jj][k]); */
                   4976:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4977:                s1++; 
1.251     brouard  4978:              } /* end jj */
                   4979:            } /* end k!= i */
                   4980:          } /* end k */
1.265     brouard  4981:        } /* end i, s1 */
1.251     brouard  4982:       } /* end j !=0 */
                   4983:     } /* end selected combination of covariate j1 */
                   4984:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   4985:       printf("#Freqsummary: Starting values for the constants:\n");
                   4986:       fprintf(ficlog,"\n");
1.265     brouard  4987:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4988:        for(k=1; k <=(nlstate+ndeath); k++){
                   4989:          if (k != i) {
                   4990:            printf("%d%d ",i,k);
                   4991:            fprintf(ficlog,"%d%d ",i,k);
                   4992:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  4993:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  4994:              if(jj==1){ /* Age has to be done */
1.265     brouard  4995:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   4996:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4997:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  4998:              }
                   4999:              /* printf("%12.7f )", param[i][jj][k]); */
                   5000:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5001:              s1++; 
1.250     brouard  5002:            }
1.251     brouard  5003:            printf("\n");
                   5004:            fprintf(ficlog,"\n");
1.250     brouard  5005:          }
                   5006:        }
1.284     brouard  5007:       } /* end of state i */
1.251     brouard  5008:       printf("#Freqsummary\n");
                   5009:       fprintf(ficlog,"\n");
1.265     brouard  5010:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   5011:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   5012:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   5013:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5014:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5015:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   5016:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   5017:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  5018:          /* } */
                   5019:        }
1.265     brouard  5020:       } /* end loop s1 */
1.251     brouard  5021:       
                   5022:       printf("\n");
                   5023:       fprintf(ficlog,"\n");
                   5024:     } /* end j=0 */
1.249     brouard  5025:   } /* end j */
1.252     brouard  5026: 
1.253     brouard  5027:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  5028:     for(i=1, jk=1; i <=nlstate; i++){
                   5029:       for(j=1; j <=nlstate+ndeath; j++){
                   5030:        if(j!=i){
                   5031:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   5032:          printf("%1d%1d",i,j);
                   5033:          fprintf(ficparo,"%1d%1d",i,j);
                   5034:          for(k=1; k<=ncovmodel;k++){
                   5035:            /*    printf(" %lf",param[i][j][k]); */
                   5036:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   5037:            p[jk]=pstart[jk];
                   5038:            printf(" %f ",pstart[jk]);
                   5039:            fprintf(ficparo," %f ",pstart[jk]);
                   5040:            jk++;
                   5041:          }
                   5042:          printf("\n");
                   5043:          fprintf(ficparo,"\n");
                   5044:        }
                   5045:       }
                   5046:     }
                   5047:   } /* end mle=-2 */
1.226     brouard  5048:   dateintmean=dateintsum/k2cpt; 
1.296     brouard  5049:   date2dmy(dateintmean,&jintmean,&mintmean,&aintmean);
1.240     brouard  5050:   
1.226     brouard  5051:   fclose(ficresp);
                   5052:   fclose(ficresphtm);
                   5053:   fclose(ficresphtmfr);
1.283     brouard  5054:   free_vector(idq,1,nqfveff);
1.226     brouard  5055:   free_vector(meanq,1,nqfveff);
1.284     brouard  5056:   free_vector(stdq,1,nqfveff);
1.226     brouard  5057:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  5058:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   5059:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  5060:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5061:   free_vector(pospropt,1,nlstate);
                   5062:   free_vector(posprop,1,nlstate);
1.251     brouard  5063:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5064:   free_vector(pp,1,nlstate);
                   5065:   /* End of freqsummary */
                   5066: }
1.126     brouard  5067: 
1.268     brouard  5068: /* Simple linear regression */
                   5069: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   5070: 
                   5071:   /* y=a+bx regression */
                   5072:   double   sumx = 0.0;                        /* sum of x                      */
                   5073:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   5074:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   5075:   double   sumy = 0.0;                        /* sum of y                      */
                   5076:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   5077:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   5078:   double yhat;
                   5079:   
                   5080:   double denom=0;
                   5081:   int i;
                   5082:   int ne=*no;
                   5083:   
                   5084:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5085:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5086:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5087:       continue;
                   5088:     }
                   5089:     ne=ne+1;
                   5090:     sumx  += x[i];       
                   5091:     sumx2 += x[i]*x[i];  
                   5092:     sumxy += x[i] * y[i];
                   5093:     sumy  += y[i];      
                   5094:     sumy2 += y[i]*y[i]; 
                   5095:     denom = (ne * sumx2 - sumx*sumx);
                   5096:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5097:   } 
                   5098:   
                   5099:   denom = (ne * sumx2 - sumx*sumx);
                   5100:   if (denom == 0) {
                   5101:     // vertical, slope m is infinity
                   5102:     *b = INFINITY;
                   5103:     *a = 0;
                   5104:     if (r) *r = 0;
                   5105:     return 1;
                   5106:   }
                   5107:   
                   5108:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5109:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5110:   if (r!=NULL) {
                   5111:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5112:       sqrt((sumx2 - sumx*sumx/ne) *
                   5113:           (sumy2 - sumy*sumy/ne));
                   5114:   }
                   5115:   *no=ne;
                   5116:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5117:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5118:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5119:       continue;
                   5120:     }
                   5121:     ne=ne+1;
                   5122:     yhat = y[i] - *a -*b* x[i];
                   5123:     sume2  += yhat * yhat ;       
                   5124:     
                   5125:     denom = (ne * sumx2 - sumx*sumx);
                   5126:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5127:   } 
                   5128:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5129:   *sa= *sb * sqrt(sumx2/ne);
                   5130:   
                   5131:   return 0; 
                   5132: }
                   5133: 
1.126     brouard  5134: /************ Prevalence ********************/
1.227     brouard  5135: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5136: {  
                   5137:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5138:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5139:      We still use firstpass and lastpass as another selection.
                   5140:   */
1.126     brouard  5141:  
1.227     brouard  5142:   int i, m, jk, j1, bool, z1,j, iv;
                   5143:   int mi; /* Effective wave */
                   5144:   int iage;
                   5145:   double agebegin, ageend;
                   5146: 
                   5147:   double **prop;
                   5148:   double posprop; 
                   5149:   double  y2; /* in fractional years */
                   5150:   int iagemin, iagemax;
                   5151:   int first; /** to stop verbosity which is redirected to log file */
                   5152: 
                   5153:   iagemin= (int) agemin;
                   5154:   iagemax= (int) agemax;
                   5155:   /*pp=vector(1,nlstate);*/
1.251     brouard  5156:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5157:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5158:   j1=0;
1.222     brouard  5159:   
1.227     brouard  5160:   /*j=cptcoveff;*/
                   5161:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5162:   
1.288     brouard  5163:   first=0;
1.227     brouard  5164:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5165:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5166:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5167:        prop[i][iage]=0.0;
                   5168:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5169:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5170:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5171:     
                   5172:     for (i=1; i<=imx; i++) { /* Each individual */
                   5173:       bool=1;
                   5174:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5175:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5176:        m=mw[mi][i];
                   5177:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5178:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5179:        for (z1=1; z1<=cptcoveff; z1++){
                   5180:          if( Fixed[Tmodelind[z1]]==1){
                   5181:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5182:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5183:              bool=0;
                   5184:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5185:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5186:              bool=0;
                   5187:            }
                   5188:        }
                   5189:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5190:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5191:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5192:          if(m >=firstpass && m <=lastpass){
                   5193:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5194:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5195:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5196:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5197:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5198:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5199:                exit(1);
                   5200:              }
                   5201:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5202:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5203:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5204:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5205:              } /* end valid statuses */ 
                   5206:            } /* end selection of dates */
                   5207:          } /* end selection of waves */
                   5208:        } /* end bool */
                   5209:       } /* end wave */
                   5210:     } /* end individual */
                   5211:     for(i=iagemin; i <= iagemax+3; i++){  
                   5212:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5213:        posprop += prop[jk][i]; 
                   5214:       } 
                   5215:       
                   5216:       for(jk=1; jk <=nlstate ; jk++){      
                   5217:        if( i <=  iagemax){ 
                   5218:          if(posprop>=1.e-5){ 
                   5219:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5220:          } else{
1.288     brouard  5221:            if(!first){
                   5222:              first=1;
1.266     brouard  5223:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5224:            }else{
1.288     brouard  5225:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5226:            }
                   5227:          }
                   5228:        } 
                   5229:       }/* end jk */ 
                   5230:     }/* end i */ 
1.222     brouard  5231:      /*} *//* end i1 */
1.227     brouard  5232:   } /* end j1 */
1.222     brouard  5233:   
1.227     brouard  5234:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5235:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5236:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5237: }  /* End of prevalence */
1.126     brouard  5238: 
                   5239: /************* Waves Concatenation ***************/
                   5240: 
                   5241: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5242: {
1.298     brouard  5243:   /* Concatenates waves: wav[i] is the number of effective (useful waves in the sense that a non interview is useless) of individual i.
1.126     brouard  5244:      Death is a valid wave (if date is known).
                   5245:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5246:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
1.298     brouard  5247:      and mw[mi+1][i]. dh depends on stepm. s[m][i] exists for any wave from firstpass to lastpass
1.227     brouard  5248:   */
1.126     brouard  5249: 
1.224     brouard  5250:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5251:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5252:      double sum=0., jmean=0.;*/
1.224     brouard  5253:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5254:   int j, k=0,jk, ju, jl;
                   5255:   double sum=0.;
                   5256:   first=0;
1.214     brouard  5257:   firstwo=0;
1.217     brouard  5258:   firsthree=0;
1.218     brouard  5259:   firstfour=0;
1.164     brouard  5260:   jmin=100000;
1.126     brouard  5261:   jmax=-1;
                   5262:   jmean=0.;
1.224     brouard  5263: 
                   5264: /* Treating live states */
1.214     brouard  5265:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5266:     mi=0;  /* First valid wave */
1.227     brouard  5267:     mli=0; /* Last valid wave */
1.126     brouard  5268:     m=firstpass;
1.214     brouard  5269:     while(s[m][i] <= nlstate){  /* a live state */
1.227     brouard  5270:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5271:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5272:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
                   5273:        mw[++mi][i]=m;
                   5274:        mli=m;
1.224     brouard  5275:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5276:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5277:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5278:       }
1.227     brouard  5279:       else{ /* m >= lastpass, eventual special issue with warning */
1.224     brouard  5280: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5281:        break;
1.224     brouard  5282: #else
1.227     brouard  5283:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){
                   5284:          if(firsthree == 0){
1.302     brouard  5285:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5286:            firsthree=1;
                   5287:          }
1.302     brouard  5288:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5289:          mw[++mi][i]=m;
                   5290:          mli=m;
                   5291:        }
                   5292:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5293:          nbwarn++;
                   5294:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified? */
                   5295:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5296:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5297:          }
                   5298:          break;
                   5299:        }
                   5300:        break;
1.224     brouard  5301: #endif
1.227     brouard  5302:       }/* End m >= lastpass */
1.126     brouard  5303:     }/* end while */
1.224     brouard  5304: 
1.227     brouard  5305:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5306:     /* After last pass */
1.224     brouard  5307: /* Treating death states */
1.214     brouard  5308:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5309:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5310:       /* } */
1.126     brouard  5311:       mi++;    /* Death is another wave */
                   5312:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5313:       /* Only death is a correct wave */
1.126     brouard  5314:       mw[mi][i]=m;
1.257     brouard  5315:     } /* else not in a death state */
1.224     brouard  5316: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5317:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5318:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.227     brouard  5319:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* death occured before last wave and status should have been death instead of -1 */
                   5320:          nbwarn++;
                   5321:          if(firstfiv==0){
                   5322:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5323:            firstfiv=1;
                   5324:          }else{
                   5325:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d interviewed at %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
                   5326:          }
                   5327:        }else{ /* Death occured afer last wave potential bias */
                   5328:          nberr++;
                   5329:          if(firstwo==0){
1.257     brouard  5330:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5331:            firstwo=1;
                   5332:          }
1.257     brouard  5333:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictive wave at the date of last vital status scan, with a dead status or alive but unknown state status (-1). See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.227     brouard  5334:        }
1.257     brouard  5335:       }else{ /* if date of interview is unknown */
1.227     brouard  5336:        /* death is known but not confirmed by death status at any wave */
                   5337:        if(firstfour==0){
                   5338:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
                   5339:          firstfour=1;
                   5340:        }
                   5341:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], i,m );
1.214     brouard  5342:       }
1.224     brouard  5343:     } /* end if date of death is known */
                   5344: #endif
                   5345:     wav[i]=mi; /* mi should be the last effective wave (or mli) */
                   5346:     /* wav[i]=mw[mi][i]; */
1.126     brouard  5347:     if(mi==0){
                   5348:       nbwarn++;
                   5349:       if(first==0){
1.227     brouard  5350:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5351:        first=1;
1.126     brouard  5352:       }
                   5353:       if(first==1){
1.227     brouard  5354:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5355:       }
                   5356:     } /* end mi==0 */
                   5357:   } /* End individuals */
1.214     brouard  5358:   /* wav and mw are no more changed */
1.223     brouard  5359:        
1.214     brouard  5360:   
1.126     brouard  5361:   for(i=1; i<=imx; i++){
                   5362:     for(mi=1; mi<wav[i];mi++){
                   5363:       if (stepm <=0)
1.227     brouard  5364:        dh[mi][i]=1;
1.126     brouard  5365:       else{
1.260     brouard  5366:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5367:          if (agedc[i] < 2*AGESUP) {
                   5368:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5369:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5370:            else if(j<0){
                   5371:              nberr++;
                   5372:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5373:              j=1; /* Temporary Dangerous patch */
                   5374:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5375:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5376:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5377:            }
                   5378:            k=k+1;
                   5379:            if (j >= jmax){
                   5380:              jmax=j;
                   5381:              ijmax=i;
                   5382:            }
                   5383:            if (j <= jmin){
                   5384:              jmin=j;
                   5385:              ijmin=i;
                   5386:            }
                   5387:            sum=sum+j;
                   5388:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5389:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5390:          }
                   5391:        }
                   5392:        else{
                   5393:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5394: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5395:                                        
1.227     brouard  5396:          k=k+1;
                   5397:          if (j >= jmax) {
                   5398:            jmax=j;
                   5399:            ijmax=i;
                   5400:          }
                   5401:          else if (j <= jmin){
                   5402:            jmin=j;
                   5403:            ijmin=i;
                   5404:          }
                   5405:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5406:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5407:          if(j<0){
                   5408:            nberr++;
                   5409:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5410:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5411:          }
                   5412:          sum=sum+j;
                   5413:        }
                   5414:        jk= j/stepm;
                   5415:        jl= j -jk*stepm;
                   5416:        ju= j -(jk+1)*stepm;
                   5417:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5418:          if(jl==0){
                   5419:            dh[mi][i]=jk;
                   5420:            bh[mi][i]=0;
                   5421:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5422:                  * to avoid the price of an extra matrix product in likelihood */
                   5423:            dh[mi][i]=jk+1;
                   5424:            bh[mi][i]=ju;
                   5425:          }
                   5426:        }else{
                   5427:          if(jl <= -ju){
                   5428:            dh[mi][i]=jk;
                   5429:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5430:                                 * is higher than the multiple of stepm and negative otherwise.
                   5431:                                 */
                   5432:          }
                   5433:          else{
                   5434:            dh[mi][i]=jk+1;
                   5435:            bh[mi][i]=ju;
                   5436:          }
                   5437:          if(dh[mi][i]==0){
                   5438:            dh[mi][i]=1; /* At least one step */
                   5439:            bh[mi][i]=ju; /* At least one step */
                   5440:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5441:          }
                   5442:        } /* end if mle */
1.126     brouard  5443:       }
                   5444:     } /* end wave */
                   5445:   }
                   5446:   jmean=sum/k;
                   5447:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5448:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5449: }
1.126     brouard  5450: 
                   5451: /*********** Tricode ****************************/
1.220     brouard  5452:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5453:  {
                   5454:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5455:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5456:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5457:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5458:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5459:     */
1.130     brouard  5460: 
1.242     brouard  5461:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5462:    int modmaxcovj=0; /* Modality max of covariates j */
                   5463:    int cptcode=0; /* Modality max of covariates j */
                   5464:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5465: 
                   5466: 
1.242     brouard  5467:    /* cptcoveff=0;  */
                   5468:    /* *cptcov=0; */
1.126     brouard  5469:  
1.242     brouard  5470:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5471:    for (k=1; k <= maxncov; k++)
                   5472:      for(j=1; j<=2; j++)
                   5473:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5474: 
1.242     brouard  5475:    /* Loop on covariates without age and products and no quantitative variable */
                   5476:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5477:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5478:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5479:        switch(Fixed[k]) {
                   5480:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
                   5481:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5482:           ij=(int)(covar[Tvar[k]][i]);
                   5483:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5484:            * If product of Vn*Vm, still boolean *:
                   5485:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5486:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5487:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5488:              modality of the nth covariate of individual i. */
                   5489:           if (ij > modmaxcovj)
                   5490:             modmaxcovj=ij; 
                   5491:           else if (ij < modmincovj) 
                   5492:             modmincovj=ij; 
1.287     brouard  5493:           if (ij <0 || ij >1 ){
                   5494:             printf("Information, IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5495:             fprintf(ficlog,"Information, currently IMaCh doesn't treat covariate with missing values (-1), individual %d will be skipped.\n",i);
                   5496:           }
                   5497:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5498:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5499:             exit(1);
                   5500:           }else
                   5501:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5502:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5503:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5504:           /* getting the maximum value of the modality of the covariate
                   5505:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5506:              female ies 1, then modmaxcovj=1.
                   5507:           */
                   5508:         } /* end for loop on individuals i */
                   5509:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5510:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5511:         cptcode=modmaxcovj;
                   5512:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5513:         /*for (i=0; i<=cptcode; i++) {*/
                   5514:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5515:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5516:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5517:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5518:             if( j != -1){
                   5519:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5520:                                  covariate for which somebody answered excluding 
                   5521:                                  undefined. Usually 2: 0 and 1. */
                   5522:             }
                   5523:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5524:                                     covariate for which somebody answered including 
                   5525:                                     undefined. Usually 3: -1, 0 and 1. */
                   5526:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5527:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5528:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5529:                        
1.242     brouard  5530:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5531:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5532:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5533:         /* modmincovj=3; modmaxcovj = 7; */
                   5534:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5535:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5536:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5537:         /* nbcode[Tvar[j]][ij]=k; */
                   5538:         /* nbcode[Tvar[j]][1]=0; */
                   5539:         /* nbcode[Tvar[j]][2]=1; */
                   5540:         /* nbcode[Tvar[j]][3]=2; */
                   5541:         /* To be continued (not working yet). */
                   5542:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5543: 
                   5544:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5545:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5546:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5547:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5548:         /*, could be restored in the future */
                   5549:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5550:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5551:             break;
                   5552:           }
                   5553:           ij++;
1.287     brouard  5554:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5555:           cptcode = ij; /* New max modality for covar j */
                   5556:         } /* end of loop on modality i=-1 to 1 or more */
                   5557:         break;
                   5558:        case 1: /* Testing on varying covariate, could be simple and
                   5559:                * should look at waves or product of fixed *
                   5560:                * varying. No time to test -1, assuming 0 and 1 only */
                   5561:         ij=0;
                   5562:         for(i=0; i<=1;i++){
                   5563:           nbcode[Tvar[k]][++ij]=i;
                   5564:         }
                   5565:         break;
                   5566:        default:
                   5567:         break;
                   5568:        } /* end switch */
                   5569:      } /* end dummy test */
1.287     brouard  5570:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5571:   
                   5572:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5573:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5574:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5575:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5576:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5577:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5578:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5579:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5580:   
                   5581:    ij=0;
                   5582:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5583:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5584:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5585:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5586:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5587:        /* If product not in single variable we don't print results */
                   5588:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5589:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5590:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5591:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5592:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5593:        if(Fixed[k]!=0)
                   5594:         anyvaryingduminmodel=1;
                   5595:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5596:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5597:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5598:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5599:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5600:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5601:      } 
                   5602:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5603:    /* ij--; */
                   5604:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5605:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5606:                * because they can be excluded from the model and real
                   5607:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5608:    for(j=ij+1; j<= cptcovt; j++){
                   5609:      Tvaraff[j]=0;
                   5610:      Tmodelind[j]=0;
                   5611:    }
                   5612:    for(j=ntveff+1; j<= cptcovt; j++){
                   5613:      TmodelInvind[j]=0;
                   5614:    }
                   5615:    /* To be sorted */
                   5616:    ;
                   5617:  }
1.126     brouard  5618: 
1.145     brouard  5619: 
1.126     brouard  5620: /*********** Health Expectancies ****************/
                   5621: 
1.235     brouard  5622:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5623: 
                   5624: {
                   5625:   /* Health expectancies, no variances */
1.164     brouard  5626:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5627:   int nhstepma, nstepma; /* Decreasing with age */
                   5628:   double age, agelim, hf;
                   5629:   double ***p3mat;
                   5630:   double eip;
                   5631: 
1.238     brouard  5632:   /* pstamp(ficreseij); */
1.126     brouard  5633:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5634:   fprintf(ficreseij,"# Age");
                   5635:   for(i=1; i<=nlstate;i++){
                   5636:     for(j=1; j<=nlstate;j++){
                   5637:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5638:     }
                   5639:     fprintf(ficreseij," e%1d. ",i);
                   5640:   }
                   5641:   fprintf(ficreseij,"\n");
                   5642: 
                   5643:   
                   5644:   if(estepm < stepm){
                   5645:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5646:   }
                   5647:   else  hstepm=estepm;   
                   5648:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5649:    * This is mainly to measure the difference between two models: for example
                   5650:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5651:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5652:    * progression in between and thus overestimating or underestimating according
                   5653:    * to the curvature of the survival function. If, for the same date, we 
                   5654:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5655:    * to compare the new estimate of Life expectancy with the same linear 
                   5656:    * hypothesis. A more precise result, taking into account a more precise
                   5657:    * curvature will be obtained if estepm is as small as stepm. */
                   5658: 
                   5659:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5660:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5661:      nhstepm is the number of hstepm from age to agelim 
                   5662:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5663:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5664:      and note for a fixed period like estepm months */
                   5665:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5666:      survival function given by stepm (the optimization length). Unfortunately it
                   5667:      means that if the survival funtion is printed only each two years of age and if
                   5668:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5669:      results. So we changed our mind and took the option of the best precision.
                   5670:   */
                   5671:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5672: 
                   5673:   agelim=AGESUP;
                   5674:   /* If stepm=6 months */
                   5675:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5676:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5677:     
                   5678: /* nhstepm age range expressed in number of stepm */
                   5679:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5680:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5681:   /* if (stepm >= YEARM) hstepm=1;*/
                   5682:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5683:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5684: 
                   5685:   for (age=bage; age<=fage; age ++){ 
                   5686:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5687:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5688:     /* if (stepm >= YEARM) hstepm=1;*/
                   5689:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5690: 
                   5691:     /* If stepm=6 months */
                   5692:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5693:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5694:     
1.235     brouard  5695:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5696:     
                   5697:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5698:     
                   5699:     printf("%d|",(int)age);fflush(stdout);
                   5700:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5701:     
                   5702:     /* Computing expectancies */
                   5703:     for(i=1; i<=nlstate;i++)
                   5704:       for(j=1; j<=nlstate;j++)
                   5705:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5706:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5707:          
                   5708:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5709: 
                   5710:        }
                   5711: 
                   5712:     fprintf(ficreseij,"%3.0f",age );
                   5713:     for(i=1; i<=nlstate;i++){
                   5714:       eip=0;
                   5715:       for(j=1; j<=nlstate;j++){
                   5716:        eip +=eij[i][j][(int)age];
                   5717:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5718:       }
                   5719:       fprintf(ficreseij,"%9.4f", eip );
                   5720:     }
                   5721:     fprintf(ficreseij,"\n");
                   5722:     
                   5723:   }
                   5724:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5725:   printf("\n");
                   5726:   fprintf(ficlog,"\n");
                   5727:   
                   5728: }
                   5729: 
1.235     brouard  5730:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5731: 
                   5732: {
                   5733:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5734:      to initial status i, ei. .
1.126     brouard  5735:   */
                   5736:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5737:   int nhstepma, nstepma; /* Decreasing with age */
                   5738:   double age, agelim, hf;
                   5739:   double ***p3matp, ***p3matm, ***varhe;
                   5740:   double **dnewm,**doldm;
                   5741:   double *xp, *xm;
                   5742:   double **gp, **gm;
                   5743:   double ***gradg, ***trgradg;
                   5744:   int theta;
                   5745: 
                   5746:   double eip, vip;
                   5747: 
                   5748:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5749:   xp=vector(1,npar);
                   5750:   xm=vector(1,npar);
                   5751:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5752:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5753:   
                   5754:   pstamp(ficresstdeij);
                   5755:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5756:   fprintf(ficresstdeij,"# Age");
                   5757:   for(i=1; i<=nlstate;i++){
                   5758:     for(j=1; j<=nlstate;j++)
                   5759:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5760:     fprintf(ficresstdeij," e%1d. ",i);
                   5761:   }
                   5762:   fprintf(ficresstdeij,"\n");
                   5763: 
                   5764:   pstamp(ficrescveij);
                   5765:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5766:   fprintf(ficrescveij,"# Age");
                   5767:   for(i=1; i<=nlstate;i++)
                   5768:     for(j=1; j<=nlstate;j++){
                   5769:       cptj= (j-1)*nlstate+i;
                   5770:       for(i2=1; i2<=nlstate;i2++)
                   5771:        for(j2=1; j2<=nlstate;j2++){
                   5772:          cptj2= (j2-1)*nlstate+i2;
                   5773:          if(cptj2 <= cptj)
                   5774:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5775:        }
                   5776:     }
                   5777:   fprintf(ficrescveij,"\n");
                   5778:   
                   5779:   if(estepm < stepm){
                   5780:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5781:   }
                   5782:   else  hstepm=estepm;   
                   5783:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5784:    * This is mainly to measure the difference between two models: for example
                   5785:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5786:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5787:    * progression in between and thus overestimating or underestimating according
                   5788:    * to the curvature of the survival function. If, for the same date, we 
                   5789:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5790:    * to compare the new estimate of Life expectancy with the same linear 
                   5791:    * hypothesis. A more precise result, taking into account a more precise
                   5792:    * curvature will be obtained if estepm is as small as stepm. */
                   5793: 
                   5794:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5795:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5796:      nhstepm is the number of hstepm from age to agelim 
                   5797:      nstepm is the number of stepm from age to agelin. 
                   5798:      Look at hpijx to understand the reason of that which relies in memory size
                   5799:      and note for a fixed period like estepm months */
                   5800:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5801:      survival function given by stepm (the optimization length). Unfortunately it
                   5802:      means that if the survival funtion is printed only each two years of age and if
                   5803:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5804:      results. So we changed our mind and took the option of the best precision.
                   5805:   */
                   5806:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5807: 
                   5808:   /* If stepm=6 months */
                   5809:   /* nhstepm age range expressed in number of stepm */
                   5810:   agelim=AGESUP;
                   5811:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5812:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5813:   /* if (stepm >= YEARM) hstepm=1;*/
                   5814:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5815:   
                   5816:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5817:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5818:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5819:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5820:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5821:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5822: 
                   5823:   for (age=bage; age<=fage; age ++){ 
                   5824:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5825:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5826:     /* if (stepm >= YEARM) hstepm=1;*/
                   5827:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5828:                
1.126     brouard  5829:     /* If stepm=6 months */
                   5830:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5831:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5832:     
                   5833:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5834:                
1.126     brouard  5835:     /* Computing  Variances of health expectancies */
                   5836:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5837:        decrease memory allocation */
                   5838:     for(theta=1; theta <=npar; theta++){
                   5839:       for(i=1; i<=npar; i++){ 
1.222     brouard  5840:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5841:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5842:       }
1.235     brouard  5843:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5844:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5845:                        
1.126     brouard  5846:       for(j=1; j<= nlstate; j++){
1.222     brouard  5847:        for(i=1; i<=nlstate; i++){
                   5848:          for(h=0; h<=nhstepm-1; h++){
                   5849:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5850:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5851:          }
                   5852:        }
1.126     brouard  5853:       }
1.218     brouard  5854:                        
1.126     brouard  5855:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5856:        for(h=0; h<=nhstepm-1; h++){
                   5857:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5858:        }
1.126     brouard  5859:     }/* End theta */
                   5860:     
                   5861:     
                   5862:     for(h=0; h<=nhstepm-1; h++)
                   5863:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5864:        for(theta=1; theta <=npar; theta++)
                   5865:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5866:     
1.218     brouard  5867:                
1.222     brouard  5868:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5869:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5870:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5871:                
1.222     brouard  5872:     printf("%d|",(int)age);fflush(stdout);
                   5873:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5874:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5875:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5876:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5877:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5878:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5879:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5880:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5881:       }
                   5882:     }
1.218     brouard  5883:                
1.126     brouard  5884:     /* Computing expectancies */
1.235     brouard  5885:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5886:     for(i=1; i<=nlstate;i++)
                   5887:       for(j=1; j<=nlstate;j++)
1.222     brouard  5888:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5889:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5890:                                        
1.222     brouard  5891:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5892:                                        
1.222     brouard  5893:        }
1.269     brouard  5894: 
                   5895:     /* Standard deviation of expectancies ij */                
1.126     brouard  5896:     fprintf(ficresstdeij,"%3.0f",age );
                   5897:     for(i=1; i<=nlstate;i++){
                   5898:       eip=0.;
                   5899:       vip=0.;
                   5900:       for(j=1; j<=nlstate;j++){
1.222     brouard  5901:        eip += eij[i][j][(int)age];
                   5902:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5903:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5904:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5905:       }
                   5906:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5907:     }
                   5908:     fprintf(ficresstdeij,"\n");
1.218     brouard  5909:                
1.269     brouard  5910:     /* Variance of expectancies ij */          
1.126     brouard  5911:     fprintf(ficrescveij,"%3.0f",age );
                   5912:     for(i=1; i<=nlstate;i++)
                   5913:       for(j=1; j<=nlstate;j++){
1.222     brouard  5914:        cptj= (j-1)*nlstate+i;
                   5915:        for(i2=1; i2<=nlstate;i2++)
                   5916:          for(j2=1; j2<=nlstate;j2++){
                   5917:            cptj2= (j2-1)*nlstate+i2;
                   5918:            if(cptj2 <= cptj)
                   5919:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5920:          }
1.126     brouard  5921:       }
                   5922:     fprintf(ficrescveij,"\n");
1.218     brouard  5923:                
1.126     brouard  5924:   }
                   5925:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5926:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5927:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5928:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5929:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5930:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5931:   printf("\n");
                   5932:   fprintf(ficlog,"\n");
1.218     brouard  5933:        
1.126     brouard  5934:   free_vector(xm,1,npar);
                   5935:   free_vector(xp,1,npar);
                   5936:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5937:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5938:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5939: }
1.218     brouard  5940:  
1.126     brouard  5941: /************ Variance ******************/
1.235     brouard  5942:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5943:  {
1.279     brouard  5944:    /** Variance of health expectancies 
                   5945:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5946:     * double **newm;
                   5947:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5948:     */
1.218     brouard  5949:   
                   5950:    /* int movingaverage(); */
                   5951:    double **dnewm,**doldm;
                   5952:    double **dnewmp,**doldmp;
                   5953:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  5954:    int first=0;
1.218     brouard  5955:    int k;
                   5956:    double *xp;
1.279     brouard  5957:    double **gp, **gm;  /**< for var eij */
                   5958:    double ***gradg, ***trgradg; /**< for var eij */
                   5959:    double **gradgp, **trgradgp; /**< for var p point j */
                   5960:    double *gpp, *gmp; /**< for var p point j */
                   5961:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5962:    double ***p3mat;
                   5963:    double age,agelim, hf;
                   5964:    /* double ***mobaverage; */
                   5965:    int theta;
                   5966:    char digit[4];
                   5967:    char digitp[25];
                   5968: 
                   5969:    char fileresprobmorprev[FILENAMELENGTH];
                   5970: 
                   5971:    if(popbased==1){
                   5972:      if(mobilav!=0)
                   5973:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   5974:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   5975:    }
                   5976:    else 
                   5977:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  5978: 
1.218     brouard  5979:    /* if (mobilav!=0) { */
                   5980:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   5981:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   5982:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   5983:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   5984:    /*   } */
                   5985:    /* } */
                   5986: 
                   5987:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   5988:    sprintf(digit,"%-d",ij);
                   5989:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   5990:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   5991:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   5992:    strcat(fileresprobmorprev,fileresu);
                   5993:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   5994:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   5995:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   5996:    }
                   5997:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5998:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   5999:    pstamp(ficresprobmorprev);
                   6000:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  6001:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   6002:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   6003:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   6004:    }
                   6005:    for(j=1;j<=cptcoveff;j++) 
                   6006:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   6007:    fprintf(ficresprobmorprev,"\n");
                   6008: 
1.218     brouard  6009:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   6010:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6011:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   6012:      for(i=1; i<=nlstate;i++)
                   6013:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   6014:    }  
                   6015:    fprintf(ficresprobmorprev,"\n");
                   6016:   
                   6017:    fprintf(ficgp,"\n# Routine varevsij");
                   6018:    fprintf(ficgp,"\nunset title \n");
                   6019:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   6020:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   6021:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  6022: 
1.218     brouard  6023:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6024:    pstamp(ficresvij);
                   6025:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   6026:    if(popbased==1)
                   6027:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   6028:    else
                   6029:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   6030:    fprintf(ficresvij,"# Age");
                   6031:    for(i=1; i<=nlstate;i++)
                   6032:      for(j=1; j<=nlstate;j++)
                   6033:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   6034:    fprintf(ficresvij,"\n");
                   6035: 
                   6036:    xp=vector(1,npar);
                   6037:    dnewm=matrix(1,nlstate,1,npar);
                   6038:    doldm=matrix(1,nlstate,1,nlstate);
                   6039:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   6040:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6041: 
                   6042:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   6043:    gpp=vector(nlstate+1,nlstate+ndeath);
                   6044:    gmp=vector(nlstate+1,nlstate+ndeath);
                   6045:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  6046:   
1.218     brouard  6047:    if(estepm < stepm){
                   6048:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   6049:    }
                   6050:    else  hstepm=estepm;   
                   6051:    /* For example we decided to compute the life expectancy with the smallest unit */
                   6052:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6053:       nhstepm is the number of hstepm from age to agelim 
                   6054:       nstepm is the number of stepm from age to agelim. 
                   6055:       Look at function hpijx to understand why because of memory size limitations, 
                   6056:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   6057:       survival function given by stepm (the optimization length). Unfortunately it
                   6058:       means that if the survival funtion is printed every two years of age and if
                   6059:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6060:       results. So we changed our mind and took the option of the best precision.
                   6061:    */
                   6062:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6063:    agelim = AGESUP;
                   6064:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6065:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6066:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6067:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6068:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   6069:      gp=matrix(0,nhstepm,1,nlstate);
                   6070:      gm=matrix(0,nhstepm,1,nlstate);
                   6071:                
                   6072:                
                   6073:      for(theta=1; theta <=npar; theta++){
                   6074:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   6075:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6076:        }
1.279     brouard  6077:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   6078:        * returns into prlim .
1.288     brouard  6079:        */
1.242     brouard  6080:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  6081: 
                   6082:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6083:        if (popbased==1) {
                   6084:         if(mobilav ==0){
                   6085:           for(i=1; i<=nlstate;i++)
                   6086:             prlim[i][i]=probs[(int)age][i][ij];
                   6087:         }else{ /* mobilav */ 
                   6088:           for(i=1; i<=nlstate;i++)
                   6089:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6090:         }
                   6091:        }
1.295     brouard  6092:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}x\f$ at horizon h.
1.279     brouard  6093:        */                      
                   6094:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292     brouard  6095:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6096:        * at horizon h in state j including mortality.
                   6097:        */
1.218     brouard  6098:        for(j=1; j<= nlstate; j++){
                   6099:         for(h=0; h<=nhstepm; h++){
                   6100:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6101:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6102:         }
                   6103:        }
1.279     brouard  6104:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6105:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6106:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6107:        */
                   6108:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6109:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6110:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6111:        }
                   6112:        
                   6113:        /* Again with minus shift */
1.218     brouard  6114:                        
                   6115:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6116:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6117: 
1.242     brouard  6118:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6119:                        
                   6120:        if (popbased==1) {
                   6121:         if(mobilav ==0){
                   6122:           for(i=1; i<=nlstate;i++)
                   6123:             prlim[i][i]=probs[(int)age][i][ij];
                   6124:         }else{ /* mobilav */ 
                   6125:           for(i=1; i<=nlstate;i++)
                   6126:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6127:         }
                   6128:        }
                   6129:                        
1.235     brouard  6130:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6131:                        
                   6132:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6133:         for(h=0; h<=nhstepm; h++){
                   6134:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6135:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6136:         }
                   6137:        }
                   6138:        /* This for computing probability of death (h=1 means
                   6139:          computed over hstepm matrices product = hstepm*stepm months) 
                   6140:          as a weighted average of prlim.
                   6141:        */
                   6142:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6143:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6144:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6145:        }    
1.279     brouard  6146:        /* end shifting computations */
                   6147: 
                   6148:        /**< Computing gradient matrix at horizon h 
                   6149:        */
1.218     brouard  6150:        for(j=1; j<= nlstate; j++) /* vareij */
                   6151:         for(h=0; h<=nhstepm; h++){
                   6152:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6153:         }
1.279     brouard  6154:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6155:        */
                   6156:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6157:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6158:        }
                   6159:                        
                   6160:      } /* End theta */
1.279     brouard  6161:      
                   6162:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6163:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6164:                
                   6165:      for(h=0; h<=nhstepm; h++) /* veij */
                   6166:        for(j=1; j<=nlstate;j++)
                   6167:         for(theta=1; theta <=npar; theta++)
                   6168:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6169:                
                   6170:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6171:        for(theta=1; theta <=npar; theta++)
                   6172:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6173:      /**< as well as its transposed matrix 
                   6174:       */               
1.218     brouard  6175:                
                   6176:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6177:      for(i=1;i<=nlstate;i++)
                   6178:        for(j=1;j<=nlstate;j++)
                   6179:         vareij[i][j][(int)age] =0.;
1.279     brouard  6180: 
                   6181:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6182:       * and k (nhstepm) formula 15 of article
                   6183:       * Lievre-Brouard-Heathcote
                   6184:       */
                   6185:      
1.218     brouard  6186:      for(h=0;h<=nhstepm;h++){
                   6187:        for(k=0;k<=nhstepm;k++){
                   6188:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6189:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6190:         for(i=1;i<=nlstate;i++)
                   6191:           for(j=1;j<=nlstate;j++)
                   6192:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6193:        }
                   6194:      }
                   6195:                
1.279     brouard  6196:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6197:       * p.j overall mortality formula 49 but computed directly because
                   6198:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6199:       * wix is independent of theta.
                   6200:       */
1.218     brouard  6201:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6202:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6203:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6204:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6205:         varppt[j][i]=doldmp[j][i];
                   6206:      /* end ppptj */
                   6207:      /*  x centered again */
                   6208:                
1.242     brouard  6209:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6210:                
                   6211:      if (popbased==1) {
                   6212:        if(mobilav ==0){
                   6213:         for(i=1; i<=nlstate;i++)
                   6214:           prlim[i][i]=probs[(int)age][i][ij];
                   6215:        }else{ /* mobilav */ 
                   6216:         for(i=1; i<=nlstate;i++)
                   6217:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6218:        }
                   6219:      }
                   6220:                
                   6221:      /* This for computing probability of death (h=1 means
                   6222:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6223:        as a weighted average of prlim.
                   6224:      */
1.235     brouard  6225:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6226:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6227:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6228:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6229:      }    
                   6230:      /* end probability of death */
                   6231:                
                   6232:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6233:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6234:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6235:        for(i=1; i<=nlstate;i++){
                   6236:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6237:        }
                   6238:      } 
                   6239:      fprintf(ficresprobmorprev,"\n");
                   6240:                
                   6241:      fprintf(ficresvij,"%.0f ",age );
                   6242:      for(i=1; i<=nlstate;i++)
                   6243:        for(j=1; j<=nlstate;j++){
                   6244:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6245:        }
                   6246:      fprintf(ficresvij,"\n");
                   6247:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6248:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6249:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6250:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6251:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6252:    } /* End age */
                   6253:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6254:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6255:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6256:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6257:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6258:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6259:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6260:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6261:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6262:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6263:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6264:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6265:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6266:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6267:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6268:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6269:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6270:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6271:     */
1.218     brouard  6272:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6273:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6274: 
1.218     brouard  6275:    free_vector(xp,1,npar);
                   6276:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6277:    free_matrix(dnewm,1,nlstate,1,npar);
                   6278:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6279:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6280:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6281:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6282:    fclose(ficresprobmorprev);
                   6283:    fflush(ficgp);
                   6284:    fflush(fichtm); 
                   6285:  }  /* end varevsij */
1.126     brouard  6286: 
                   6287: /************ Variance of prevlim ******************/
1.269     brouard  6288:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6289: {
1.205     brouard  6290:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6291:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6292: 
1.268     brouard  6293:   double **dnewmpar,**doldm;
1.126     brouard  6294:   int i, j, nhstepm, hstepm;
                   6295:   double *xp;
                   6296:   double *gp, *gm;
                   6297:   double **gradg, **trgradg;
1.208     brouard  6298:   double **mgm, **mgp;
1.126     brouard  6299:   double age,agelim;
                   6300:   int theta;
                   6301:   
                   6302:   pstamp(ficresvpl);
1.288     brouard  6303:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6304:   fprintf(ficresvpl,"# Age ");
                   6305:   if(nresult >=1)
                   6306:     fprintf(ficresvpl," Result# ");
1.126     brouard  6307:   for(i=1; i<=nlstate;i++)
                   6308:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6309:   fprintf(ficresvpl,"\n");
                   6310: 
                   6311:   xp=vector(1,npar);
1.268     brouard  6312:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6313:   doldm=matrix(1,nlstate,1,nlstate);
                   6314:   
                   6315:   hstepm=1*YEARM; /* Every year of age */
                   6316:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6317:   agelim = AGESUP;
                   6318:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6319:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6320:     if (stepm >= YEARM) hstepm=1;
                   6321:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6322:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6323:     mgp=matrix(1,npar,1,nlstate);
                   6324:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6325:     gp=vector(1,nlstate);
                   6326:     gm=vector(1,nlstate);
                   6327: 
                   6328:     for(theta=1; theta <=npar; theta++){
                   6329:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6330:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6331:       }
1.288     brouard  6332:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6333:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6334:       /* else */
                   6335:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6336:       for(i=1;i<=nlstate;i++){
1.126     brouard  6337:        gp[i] = prlim[i][i];
1.208     brouard  6338:        mgp[theta][i] = prlim[i][i];
                   6339:       }
1.126     brouard  6340:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6341:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6342:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6343:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6344:       /* else */
                   6345:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6346:       for(i=1;i<=nlstate;i++){
1.126     brouard  6347:        gm[i] = prlim[i][i];
1.208     brouard  6348:        mgm[theta][i] = prlim[i][i];
                   6349:       }
1.126     brouard  6350:       for(i=1;i<=nlstate;i++)
                   6351:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6352:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6353:     } /* End theta */
                   6354: 
                   6355:     trgradg =matrix(1,nlstate,1,npar);
                   6356: 
                   6357:     for(j=1; j<=nlstate;j++)
                   6358:       for(theta=1; theta <=npar; theta++)
                   6359:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6360:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6361:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6362:     /*   for(j=1; j<=nlstate;j++){ */
                   6363:     /*         printf(" %d ",j); */
                   6364:     /*         for(theta=1; theta <=npar; theta++) */
                   6365:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6366:     /*         printf("\n "); */
                   6367:     /*   } */
                   6368:     /* } */
                   6369:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6370:     /*   printf("\n gradg %d ",(int)age); */
                   6371:     /*   for(j=1; j<=nlstate;j++){ */
                   6372:     /*         printf("%d ",j); */
                   6373:     /*         for(theta=1; theta <=npar; theta++) */
                   6374:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6375:     /*         printf("\n "); */
                   6376:     /*   } */
                   6377:     /* } */
1.126     brouard  6378: 
                   6379:     for(i=1;i<=nlstate;i++)
                   6380:       varpl[i][(int)age] =0.;
1.209     brouard  6381:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6382:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6383:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6384:     }else{
1.268     brouard  6385:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6386:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6387:     }
1.126     brouard  6388:     for(i=1;i<=nlstate;i++)
                   6389:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6390: 
                   6391:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6392:     if(nresult >=1)
                   6393:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6394:     for(i=1; i<=nlstate;i++){
1.126     brouard  6395:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6396:       /* for(j=1;j<=nlstate;j++) */
                   6397:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6398:     }
1.126     brouard  6399:     fprintf(ficresvpl,"\n");
                   6400:     free_vector(gp,1,nlstate);
                   6401:     free_vector(gm,1,nlstate);
1.208     brouard  6402:     free_matrix(mgm,1,npar,1,nlstate);
                   6403:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6404:     free_matrix(gradg,1,npar,1,nlstate);
                   6405:     free_matrix(trgradg,1,nlstate,1,npar);
                   6406:   } /* End age */
                   6407: 
                   6408:   free_vector(xp,1,npar);
                   6409:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6410:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6411: 
                   6412: }
                   6413: 
                   6414: 
                   6415: /************ Variance of backprevalence limit ******************/
1.269     brouard  6416:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6417: {
                   6418:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6419:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6420: 
                   6421:   double **dnewmpar,**doldm;
                   6422:   int i, j, nhstepm, hstepm;
                   6423:   double *xp;
                   6424:   double *gp, *gm;
                   6425:   double **gradg, **trgradg;
                   6426:   double **mgm, **mgp;
                   6427:   double age,agelim;
                   6428:   int theta;
                   6429:   
                   6430:   pstamp(ficresvbl);
                   6431:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6432:   fprintf(ficresvbl,"# Age ");
                   6433:   if(nresult >=1)
                   6434:     fprintf(ficresvbl," Result# ");
                   6435:   for(i=1; i<=nlstate;i++)
                   6436:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6437:   fprintf(ficresvbl,"\n");
                   6438: 
                   6439:   xp=vector(1,npar);
                   6440:   dnewmpar=matrix(1,nlstate,1,npar);
                   6441:   doldm=matrix(1,nlstate,1,nlstate);
                   6442:   
                   6443:   hstepm=1*YEARM; /* Every year of age */
                   6444:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6445:   agelim = AGEINF;
                   6446:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6447:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6448:     if (stepm >= YEARM) hstepm=1;
                   6449:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6450:     gradg=matrix(1,npar,1,nlstate);
                   6451:     mgp=matrix(1,npar,1,nlstate);
                   6452:     mgm=matrix(1,npar,1,nlstate);
                   6453:     gp=vector(1,nlstate);
                   6454:     gm=vector(1,nlstate);
                   6455: 
                   6456:     for(theta=1; theta <=npar; theta++){
                   6457:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6458:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6459:       }
                   6460:       if(mobilavproj > 0 )
                   6461:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6462:       else
                   6463:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6464:       for(i=1;i<=nlstate;i++){
                   6465:        gp[i] = bprlim[i][i];
                   6466:        mgp[theta][i] = bprlim[i][i];
                   6467:       }
                   6468:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6469:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6470:        if(mobilavproj > 0 )
                   6471:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6472:        else
                   6473:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6474:       for(i=1;i<=nlstate;i++){
                   6475:        gm[i] = bprlim[i][i];
                   6476:        mgm[theta][i] = bprlim[i][i];
                   6477:       }
                   6478:       for(i=1;i<=nlstate;i++)
                   6479:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6480:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6481:     } /* End theta */
                   6482: 
                   6483:     trgradg =matrix(1,nlstate,1,npar);
                   6484: 
                   6485:     for(j=1; j<=nlstate;j++)
                   6486:       for(theta=1; theta <=npar; theta++)
                   6487:        trgradg[j][theta]=gradg[theta][j];
                   6488:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6489:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6490:     /*   for(j=1; j<=nlstate;j++){ */
                   6491:     /*         printf(" %d ",j); */
                   6492:     /*         for(theta=1; theta <=npar; theta++) */
                   6493:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6494:     /*         printf("\n "); */
                   6495:     /*   } */
                   6496:     /* } */
                   6497:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6498:     /*   printf("\n gradg %d ",(int)age); */
                   6499:     /*   for(j=1; j<=nlstate;j++){ */
                   6500:     /*         printf("%d ",j); */
                   6501:     /*         for(theta=1; theta <=npar; theta++) */
                   6502:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6503:     /*         printf("\n "); */
                   6504:     /*   } */
                   6505:     /* } */
                   6506: 
                   6507:     for(i=1;i<=nlstate;i++)
                   6508:       varbpl[i][(int)age] =0.;
                   6509:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6510:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6511:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6512:     }else{
                   6513:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6514:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6515:     }
                   6516:     for(i=1;i<=nlstate;i++)
                   6517:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6518: 
                   6519:     fprintf(ficresvbl,"%.0f ",age );
                   6520:     if(nresult >=1)
                   6521:       fprintf(ficresvbl,"%d ",nres );
                   6522:     for(i=1; i<=nlstate;i++)
                   6523:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6524:     fprintf(ficresvbl,"\n");
                   6525:     free_vector(gp,1,nlstate);
                   6526:     free_vector(gm,1,nlstate);
                   6527:     free_matrix(mgm,1,npar,1,nlstate);
                   6528:     free_matrix(mgp,1,npar,1,nlstate);
                   6529:     free_matrix(gradg,1,npar,1,nlstate);
                   6530:     free_matrix(trgradg,1,nlstate,1,npar);
                   6531:   } /* End age */
                   6532: 
                   6533:   free_vector(xp,1,npar);
                   6534:   free_matrix(doldm,1,nlstate,1,npar);
                   6535:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6536: 
                   6537: }
                   6538: 
                   6539: /************ Variance of one-step probabilities  ******************/
                   6540: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6541:  {
                   6542:    int i, j=0,  k1, l1, tj;
                   6543:    int k2, l2, j1,  z1;
                   6544:    int k=0, l;
                   6545:    int first=1, first1, first2;
                   6546:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6547:    double **dnewm,**doldm;
                   6548:    double *xp;
                   6549:    double *gp, *gm;
                   6550:    double **gradg, **trgradg;
                   6551:    double **mu;
                   6552:    double age, cov[NCOVMAX+1];
                   6553:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6554:    int theta;
                   6555:    char fileresprob[FILENAMELENGTH];
                   6556:    char fileresprobcov[FILENAMELENGTH];
                   6557:    char fileresprobcor[FILENAMELENGTH];
                   6558:    double ***varpij;
                   6559: 
                   6560:    strcpy(fileresprob,"PROB_"); 
                   6561:    strcat(fileresprob,fileres);
                   6562:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6563:      printf("Problem with resultfile: %s\n", fileresprob);
                   6564:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6565:    }
                   6566:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6567:    strcat(fileresprobcov,fileresu);
                   6568:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6569:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6570:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6571:    }
                   6572:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6573:    strcat(fileresprobcor,fileresu);
                   6574:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6575:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6576:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6577:    }
                   6578:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6579:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6580:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6581:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6582:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6583:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6584:    pstamp(ficresprob);
                   6585:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6586:    fprintf(ficresprob,"# Age");
                   6587:    pstamp(ficresprobcov);
                   6588:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6589:    fprintf(ficresprobcov,"# Age");
                   6590:    pstamp(ficresprobcor);
                   6591:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6592:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6593: 
                   6594: 
1.222     brouard  6595:    for(i=1; i<=nlstate;i++)
                   6596:      for(j=1; j<=(nlstate+ndeath);j++){
                   6597:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6598:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6599:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6600:      }  
                   6601:    /* fprintf(ficresprob,"\n");
                   6602:       fprintf(ficresprobcov,"\n");
                   6603:       fprintf(ficresprobcor,"\n");
                   6604:    */
                   6605:    xp=vector(1,npar);
                   6606:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6607:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6608:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6609:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6610:    first=1;
                   6611:    fprintf(ficgp,"\n# Routine varprob");
                   6612:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6613:    fprintf(fichtm,"\n");
                   6614: 
1.288     brouard  6615:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6616:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6617:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6618: and drawn. It helps understanding how is the covariance between two incidences.\
                   6619:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6620:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6621: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6622: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6623: standard deviations wide on each axis. <br>\
                   6624:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6625:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6626: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6627: 
1.222     brouard  6628:    cov[1]=1;
                   6629:    /* tj=cptcoveff; */
1.225     brouard  6630:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6631:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6632:    j1=0;
1.224     brouard  6633:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6634:      if  (cptcovn>0) {
                   6635:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6636:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6637:        fprintf(ficresprob, "**********\n#\n");
                   6638:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6639:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6640:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6641:                        
1.222     brouard  6642:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6643:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6644:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6645:                        
                   6646:                        
1.222     brouard  6647:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6648:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6649:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6650:                        
1.222     brouard  6651:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6652:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6653:        fprintf(ficresprobcor, "**********\n#");    
                   6654:        if(invalidvarcomb[j1]){
                   6655:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6656:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6657:         continue;
                   6658:        }
                   6659:      }
                   6660:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6661:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6662:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6663:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6664:      for (age=bage; age<=fage; age ++){ 
                   6665:        cov[2]=age;
                   6666:        if(nagesqr==1)
                   6667:         cov[3]= age*age;
                   6668:        for (k=1; k<=cptcovn;k++) {
                   6669:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6670:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6671:                                                                    * 1  1 1 1 1
                   6672:                                                                    * 2  2 1 1 1
                   6673:                                                                    * 3  1 2 1 1
                   6674:                                                                    */
                   6675:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6676:        }
                   6677:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6678:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6679:        for (k=1; k<=cptcovprod;k++)
                   6680:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6681:                        
                   6682:                        
1.222     brouard  6683:        for(theta=1; theta <=npar; theta++){
                   6684:         for(i=1; i<=npar; i++)
                   6685:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6686:                                
1.222     brouard  6687:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6688:                                
1.222     brouard  6689:         k=0;
                   6690:         for(i=1; i<= (nlstate); i++){
                   6691:           for(j=1; j<=(nlstate+ndeath);j++){
                   6692:             k=k+1;
                   6693:             gp[k]=pmmij[i][j];
                   6694:           }
                   6695:         }
1.220     brouard  6696:                                
1.222     brouard  6697:         for(i=1; i<=npar; i++)
                   6698:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6699:                                
1.222     brouard  6700:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6701:         k=0;
                   6702:         for(i=1; i<=(nlstate); i++){
                   6703:           for(j=1; j<=(nlstate+ndeath);j++){
                   6704:             k=k+1;
                   6705:             gm[k]=pmmij[i][j];
                   6706:           }
                   6707:         }
1.220     brouard  6708:                                
1.222     brouard  6709:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6710:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6711:        }
1.126     brouard  6712: 
1.222     brouard  6713:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6714:         for(theta=1; theta <=npar; theta++)
                   6715:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6716:                        
1.222     brouard  6717:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6718:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6719:                        
1.222     brouard  6720:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6721:                        
1.222     brouard  6722:        k=0;
                   6723:        for(i=1; i<=(nlstate); i++){
                   6724:         for(j=1; j<=(nlstate+ndeath);j++){
                   6725:           k=k+1;
                   6726:           mu[k][(int) age]=pmmij[i][j];
                   6727:         }
                   6728:        }
                   6729:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6730:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6731:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6732:                        
1.222     brouard  6733:        /*printf("\n%d ",(int)age);
                   6734:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6735:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6736:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6737:         }*/
1.220     brouard  6738:                        
1.222     brouard  6739:        fprintf(ficresprob,"\n%d ",(int)age);
                   6740:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6741:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6742:                        
1.222     brouard  6743:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6744:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6745:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6746:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6747:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6748:        }
                   6749:        i=0;
                   6750:        for (k=1; k<=(nlstate);k++){
                   6751:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6752:           i++;
                   6753:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6754:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6755:           for (j=1; j<=i;j++){
                   6756:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6757:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6758:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6759:           }
                   6760:         }
                   6761:        }/* end of loop for state */
                   6762:      } /* end of loop for age */
                   6763:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6764:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6765:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6766:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6767:     
                   6768:      /* Confidence intervalle of pij  */
                   6769:      /*
                   6770:        fprintf(ficgp,"\nunset parametric;unset label");
                   6771:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6772:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6773:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6774:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6775:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6776:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6777:      */
                   6778:                
                   6779:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6780:      first1=1;first2=2;
                   6781:      for (k2=1; k2<=(nlstate);k2++){
                   6782:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6783:         if(l2==k2) continue;
                   6784:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6785:         for (k1=1; k1<=(nlstate);k1++){
                   6786:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6787:             if(l1==k1) continue;
                   6788:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6789:             if(i<=j) continue;
                   6790:             for (age=bage; age<=fage; age ++){ 
                   6791:               if ((int)age %5==0){
                   6792:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6793:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6794:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6795:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6796:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6797:                 c12=cv12/sqrt(v1*v2);
                   6798:                 /* Computing eigen value of matrix of covariance */
                   6799:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6800:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6801:                 if ((lc2 <0) || (lc1 <0) ){
                   6802:                   if(first2==1){
                   6803:                     first1=0;
                   6804:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6805:                   }
                   6806:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6807:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6808:                   /* lc2=fabs(lc2); */
                   6809:                 }
1.220     brouard  6810:                                                                
1.222     brouard  6811:                 /* Eigen vectors */
1.280     brouard  6812:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6813:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6814:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6815:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6816:                 }else
                   6817:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6818:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6819:                 v21=(lc1-v1)/cv12*v11;
                   6820:                 v12=-v21;
                   6821:                 v22=v11;
                   6822:                 tnalp=v21/v11;
                   6823:                 if(first1==1){
                   6824:                   first1=0;
                   6825:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6826:                 }
                   6827:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6828:                 /*printf(fignu*/
                   6829:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6830:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6831:                 if(first==1){
                   6832:                   first=0;
                   6833:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6834:                   fprintf(ficgp,"\nset parametric;unset label");
                   6835:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6836:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6837:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6838:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6839: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6840:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6841:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6842:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6843:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6844:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6845:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6846:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6847:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6848:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6849:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6850:                 }else{
                   6851:                   first=0;
                   6852:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6853:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6854:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6855:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6856:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6857:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6858:                 }/* if first */
                   6859:               } /* age mod 5 */
                   6860:             } /* end loop age */
                   6861:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6862:             first=1;
                   6863:           } /*l12 */
                   6864:         } /* k12 */
                   6865:        } /*l1 */
                   6866:      }/* k1 */
                   6867:    }  /* loop on combination of covariates j1 */
                   6868:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6869:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6870:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6871:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6872:    free_vector(xp,1,npar);
                   6873:    fclose(ficresprob);
                   6874:    fclose(ficresprobcov);
                   6875:    fclose(ficresprobcor);
                   6876:    fflush(ficgp);
                   6877:    fflush(fichtmcov);
                   6878:  }
1.126     brouard  6879: 
                   6880: 
                   6881: /******************* Printing html file ***********/
1.201     brouard  6882: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6883:                  int lastpass, int stepm, int weightopt, char model[],\
                   6884:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.296     brouard  6885:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int prevbcast, int estepm , \
                   6886:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateprojd, double dateback1, \
                   6887:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateprojf, double dateback2){
1.237     brouard  6888:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6889: 
                   6890:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6891:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6892: </ul>");
1.237     brouard  6893:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6894: </ul>", model);
1.214     brouard  6895:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6896:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6897:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6898:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6899:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6900:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6901:    fprintf(fichtm,"\
                   6902:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6903:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6904:    fprintf(fichtm,"\
1.217     brouard  6905:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6906:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6907:    fprintf(fichtm,"\
1.288     brouard  6908:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6909:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6910:    fprintf(fichtm,"\
1.288     brouard  6911:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  6912:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6913:    fprintf(fichtm,"\
1.211     brouard  6914:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6915:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6916:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6917:    if(prevfcast==1){
                   6918:      fprintf(fichtm,"\
                   6919:  - Prevalence projections by age and states:                           \
1.201     brouard  6920:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6921:    }
1.126     brouard  6922: 
                   6923: 
1.225     brouard  6924:    m=pow(2,cptcoveff);
1.222     brouard  6925:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6926: 
1.264     brouard  6927:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6928: 
                   6929:    jj1=0;
                   6930: 
                   6931:    fprintf(fichtm," \n<ul>");
                   6932:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6933:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6934:      if(m != 1 && TKresult[nres]!= k1)
                   6935:        continue;
                   6936:      jj1++;
                   6937:      if (cptcovn > 0) {
                   6938:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6939:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6940:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6941:        }
                   6942:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6943:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6944:        }
                   6945:        fprintf(fichtm,"\">");
                   6946:        
                   6947:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6948:        fprintf(fichtm,"************ Results for covariates");
                   6949:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6950:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6951:        }
                   6952:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6953:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6954:        }
                   6955:        if(invalidvarcomb[k1]){
                   6956:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6957:         continue;
                   6958:        }
                   6959:        fprintf(fichtm,"</a></li>");
                   6960:      } /* cptcovn >0 */
                   6961:    }
                   6962:      fprintf(fichtm," \n</ul>");
                   6963: 
1.222     brouard  6964:    jj1=0;
1.237     brouard  6965: 
                   6966:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  6967:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  6968:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  6969:        continue;
1.220     brouard  6970: 
1.222     brouard  6971:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   6972:      jj1++;
                   6973:      if (cptcovn > 0) {
1.264     brouard  6974:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   6975:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6976:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6977:        }
                   6978:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6979:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6980:        }
                   6981:        fprintf(fichtm,"\"</a>");
                   6982:  
1.222     brouard  6983:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  6984:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  6985:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6986:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   6987:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   6988:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  6989:        }
1.237     brouard  6990:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6991:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6992:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   6993:       }
                   6994:        
1.230     brouard  6995:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  6996:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   6997:        if(invalidvarcomb[k1]){
                   6998:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   6999:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   7000:         continue;
                   7001:        }
                   7002:      }
                   7003:      /* aij, bij */
1.259     brouard  7004:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  7005: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  7006:      /* Pij */
1.241     brouard  7007:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   7008: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  7009:      /* Quasi-incidences */
                   7010:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  7011:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  7012:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  7013: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   7014: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  7015:      /* Survival functions (period) in state j */
                   7016:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7017:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7018: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  7019:      }
                   7020:      /* State specific survival functions (period) */
                   7021:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7022:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
                   7023:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  7024:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  7025:      }
1.288     brouard  7026:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  7027:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7028:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7029: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  7030:      }
1.296     brouard  7031:      if(prevbcast==1){
1.288     brouard  7032:        /* Backward prevalence in each health state */
1.222     brouard  7033:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7034:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7035: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  7036:        }
1.217     brouard  7037:      }
1.222     brouard  7038:      if(prevfcast==1){
1.288     brouard  7039:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  7040:        for(cpt=1; cpt<=nlstate;cpt++){
1.288     brouard  7041:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.296     brouard  7042: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateprojd, dateprojf, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  7043:        }
                   7044:      }
1.296     brouard  7045:      if(prevbcast==1){
1.268     brouard  7046:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   7047:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  7048:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   7049:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   7050:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   7051: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7052:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  7053:        }
                   7054:      }
1.220     brouard  7055:         
1.222     brouard  7056:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  7057:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   7058: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  7059:      }
                   7060:      /* } /\* end i1 *\/ */
                   7061:    }/* End k1 */
                   7062:    fprintf(fichtm,"</ul>");
1.126     brouard  7063: 
1.222     brouard  7064:    fprintf(fichtm,"\
1.126     brouard  7065: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  7066:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  7067:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  7068: But because parameters are usually highly correlated (a higher incidence of disability \
                   7069: and a higher incidence of recovery can give very close observed transition) it might \
                   7070: be very useful to look not only at linear confidence intervals estimated from the \
                   7071: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   7072: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   7073: covariance matrix of the one-step probabilities. \
                   7074: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  7075: 
1.222     brouard  7076:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   7077:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   7078:    fprintf(fichtm,"\
1.126     brouard  7079:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7080:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  7081: 
1.222     brouard  7082:    fprintf(fichtm,"\
1.126     brouard  7083:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7084:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7085:    fprintf(fichtm,"\
1.126     brouard  7086:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7087:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7088:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7089:    fprintf(fichtm,"\
1.126     brouard  7090:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7091:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7092:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7093:    fprintf(fichtm,"\
1.288     brouard  7094:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7095:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7096:    fprintf(fichtm,"\
1.128     brouard  7097:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7098:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7099:    fprintf(fichtm,"\
1.288     brouard  7100:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7101:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7102: 
                   7103: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7104: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7105: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7106: /*     <br>",fileres,fileres,fileres,fileres); */
                   7107: /*  else  */
                   7108: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7109:    fflush(fichtm);
                   7110:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7111: 
1.225     brouard  7112:    m=pow(2,cptcoveff);
1.222     brouard  7113:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7114: 
1.222     brouard  7115:    jj1=0;
1.237     brouard  7116: 
1.241     brouard  7117:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7118:    for(k1=1; k1<=m;k1++){
1.253     brouard  7119:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7120:        continue;
1.222     brouard  7121:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7122:      jj1++;
1.126     brouard  7123:      if (cptcovn > 0) {
                   7124:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7125:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7126:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7127:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7128:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7129:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7130:       }
                   7131: 
1.126     brouard  7132:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7133: 
1.222     brouard  7134:        if(invalidvarcomb[k1]){
                   7135:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7136:         continue;
                   7137:        }
1.126     brouard  7138:      }
                   7139:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7140:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7141: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7142: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7143:      }
                   7144:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7145: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7146: true period expectancies (those weighted with period prevalences are also\
                   7147:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7148:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7149: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7150:      /* } /\* end i1 *\/ */
                   7151:    }/* End k1 */
1.241     brouard  7152:   }/* End nres */
1.222     brouard  7153:    fprintf(fichtm,"</ul>");
                   7154:    fflush(fichtm);
1.126     brouard  7155: }
                   7156: 
                   7157: /******************* Gnuplot file **************/
1.296     brouard  7158: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int prevbcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7159: 
                   7160:   char dirfileres[132],optfileres[132];
1.264     brouard  7161:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7162:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7163:   int lv=0, vlv=0, kl=0;
1.130     brouard  7164:   int ng=0;
1.201     brouard  7165:   int vpopbased;
1.223     brouard  7166:   int ioffset; /* variable offset for columns */
1.270     brouard  7167:   int iyearc=1; /* variable column for year of projection  */
                   7168:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7169:   int nres=0; /* Index of resultline */
1.266     brouard  7170:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7171: 
1.126     brouard  7172: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7173: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7174: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7175: /*   } */
                   7176: 
                   7177:   /*#ifdef windows */
                   7178:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7179:   /*#endif */
1.225     brouard  7180:   m=pow(2,cptcoveff);
1.126     brouard  7181: 
1.274     brouard  7182:   /* diagram of the model */
                   7183:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7184:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7185:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7186:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7187: 
                   7188:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7189:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7190:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7191:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7192:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7193:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7194:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7195: 
1.202     brouard  7196:   /* Contribution to likelihood */
                   7197:   /* Plot the probability implied in the likelihood */
1.223     brouard  7198:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7199:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7200:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7201:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7202: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7203:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7204: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7205:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7206:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7207:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7208:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7209:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7210:   for (i=1; i<= nlstate ; i ++) {
                   7211:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7212:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7213:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7214:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7215:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7216:     }
                   7217:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7218:   }
                   7219:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7220:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7221:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7222:   fprintf(ficgp,"\nset out;unset log\n");
                   7223:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7224: 
1.126     brouard  7225:   strcpy(dirfileres,optionfilefiname);
                   7226:   strcpy(optfileres,"vpl");
1.223     brouard  7227:   /* 1eme*/
1.238     brouard  7228:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7229:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7230:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7231:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7232:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7233:          continue;
                   7234:        /* We are interested in selected combination by the resultline */
1.246     brouard  7235:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7236:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7237:        strcpy(gplotlabel,"(");
1.238     brouard  7238:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7239:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7240:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7241:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7242:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7243:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7244:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7245:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7246:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7247:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7248:        }
                   7249:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7250:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7251:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7252:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7253:        }
                   7254:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7255:        /* printf("\n#\n"); */
1.238     brouard  7256:        fprintf(ficgp,"\n#\n");
                   7257:        if(invalidvarcomb[k1]){
1.260     brouard  7258:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7259:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7260:          continue;
                   7261:        }
1.235     brouard  7262:       
1.241     brouard  7263:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7264:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7265:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7266:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7267:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7268:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7269:       /* k1-1 error should be nres-1*/
1.238     brouard  7270:        for (i=1; i<= nlstate ; i ++) {
                   7271:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7272:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7273:        }
1.288     brouard  7274:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7275:        for (i=1; i<= nlstate ; i ++) {
                   7276:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7277:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7278:        } 
1.260     brouard  7279:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7280:        for (i=1; i<= nlstate ; i ++) {
                   7281:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7282:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7283:        }  
1.265     brouard  7284:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7285:        
                   7286:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7287:         if(cptcoveff ==0){
1.271     brouard  7288:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7289:        }else{
                   7290:          kl=0;
                   7291:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7292:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7293:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7294:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7295:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7296:            vlv= nbcode[Tvaraff[k]][lv];
                   7297:            kl++;
                   7298:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7299:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7300:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7301:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7302:            if(k==cptcoveff){
                   7303:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7304:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7305:            }else{
                   7306:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7307:              kl++;
                   7308:            }
                   7309:          } /* end covariate */
                   7310:        } /* end if no covariate */
                   7311: 
1.296     brouard  7312:        if(prevbcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
1.238     brouard  7313:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7314:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7315:          if(cptcoveff ==0){
1.245     brouard  7316:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7317:          }else{
                   7318:            kl=0;
                   7319:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7320:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7321:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7322:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7323:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7324:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7325:              kl++;
1.238     brouard  7326:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7327:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7328:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7329:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7330:              if(k==cptcoveff){
1.245     brouard  7331:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7332:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7333:              }else{
                   7334:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7335:                kl++;
                   7336:              }
                   7337:            } /* end covariate */
                   7338:          } /* end if no covariate */
1.296     brouard  7339:          if(prevbcast == 1){
1.268     brouard  7340:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7341:            /* k1-1 error should be nres-1*/
                   7342:            for (i=1; i<= nlstate ; i ++) {
                   7343:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7344:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7345:            }
1.271     brouard  7346:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7347:            for (i=1; i<= nlstate ; i ++) {
                   7348:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7349:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7350:            } 
1.276     brouard  7351:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7352:            for (i=1; i<= nlstate ; i ++) {
                   7353:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7354:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7355:            } 
1.274     brouard  7356:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7357:          } /* end if backprojcast */
1.296     brouard  7358:        } /* end if prevbcast */
1.276     brouard  7359:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7360:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7361:       } /* nres */
1.201     brouard  7362:     } /* k1 */
                   7363:   } /* cpt */
1.235     brouard  7364: 
                   7365:   
1.126     brouard  7366:   /*2 eme*/
1.238     brouard  7367:   for (k1=1; k1<= m ; k1 ++){  
                   7368:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7369:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7370:        continue;
                   7371:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7372:       strcpy(gplotlabel,"(");
1.238     brouard  7373:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7374:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7375:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7376:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7377:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7378:        vlv= nbcode[Tvaraff[k]][lv];
                   7379:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7380:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7381:       }
1.237     brouard  7382:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7383:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7384:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7385:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7386:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7387:       }
1.264     brouard  7388:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7389:       fprintf(ficgp,"\n#\n");
1.223     brouard  7390:       if(invalidvarcomb[k1]){
                   7391:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7392:        continue;
                   7393:       }
1.219     brouard  7394:                        
1.241     brouard  7395:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7396:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7397:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7398:        if(vpopbased==0){
1.238     brouard  7399:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7400:        }else
1.238     brouard  7401:          fprintf(ficgp,"\nreplot ");
                   7402:        for (i=1; i<= nlstate+1 ; i ++) {
                   7403:          k=2*i;
1.261     brouard  7404:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7405:          for (j=1; j<= nlstate+1 ; j ++) {
                   7406:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7407:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7408:          }   
                   7409:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7410:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7411:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7412:          for (j=1; j<= nlstate+1 ; j ++) {
                   7413:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7414:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7415:          }   
                   7416:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7417:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7418:          for (j=1; j<= nlstate+1 ; j ++) {
                   7419:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7420:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7421:          }   
                   7422:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7423:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7424:        } /* state */
                   7425:       } /* vpopbased */
1.264     brouard  7426:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7427:     } /* end nres */
                   7428:   } /* k1 end 2 eme*/
                   7429:        
                   7430:        
                   7431:   /*3eme*/
                   7432:   for (k1=1; k1<= m ; k1 ++){
                   7433:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7434:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7435:        continue;
                   7436: 
                   7437:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7438:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7439:        strcpy(gplotlabel,"(");
1.238     brouard  7440:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7441:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7442:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7443:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7444:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7445:          vlv= nbcode[Tvaraff[k]][lv];
                   7446:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7447:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7448:        }
                   7449:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7450:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7451:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7452:        }       
1.264     brouard  7453:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7454:        fprintf(ficgp,"\n#\n");
                   7455:        if(invalidvarcomb[k1]){
                   7456:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7457:          continue;
                   7458:        }
                   7459:                        
                   7460:        /*       k=2+nlstate*(2*cpt-2); */
                   7461:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7462:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7463:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7464:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7465: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7466:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7467:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7468:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7469:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7470:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7471:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7472:                                
1.238     brouard  7473:        */
                   7474:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7475:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7476:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7477:                                
1.238     brouard  7478:        } 
1.261     brouard  7479:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7480:       }
1.264     brouard  7481:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7482:     } /* end nres */
                   7483:   } /* end kl 3eme */
1.126     brouard  7484:   
1.223     brouard  7485:   /* 4eme */
1.201     brouard  7486:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7487:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7488:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7489:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7490:        continue;
1.238     brouard  7491:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7492:        strcpy(gplotlabel,"(");
1.238     brouard  7493:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7494:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7495:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7496:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7497:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7498:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7499:          vlv= nbcode[Tvaraff[k]][lv];
                   7500:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7501:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7502:        }
                   7503:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7504:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7505:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7506:        }       
1.264     brouard  7507:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7508:        fprintf(ficgp,"\n#\n");
                   7509:        if(invalidvarcomb[k1]){
                   7510:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7511:          continue;
1.223     brouard  7512:        }
1.238     brouard  7513:       
1.241     brouard  7514:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7515:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7516:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7517: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7518:        k=3;
                   7519:        for (i=1; i<= nlstate ; i ++){
                   7520:          if(i==1){
                   7521:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7522:          }else{
                   7523:            fprintf(ficgp,", '' ");
                   7524:          }
                   7525:          l=(nlstate+ndeath)*(i-1)+1;
                   7526:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7527:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7528:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7529:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7530:        } /* nlstate */
1.264     brouard  7531:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7532:       } /* end cpt state*/ 
                   7533:     } /* end nres */
                   7534:   } /* end covariate k1 */  
                   7535: 
1.220     brouard  7536: /* 5eme */
1.201     brouard  7537:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7538:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7539:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7540:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7541:        continue;
1.238     brouard  7542:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7543:        strcpy(gplotlabel,"(");
1.238     brouard  7544:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7545:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7546:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7547:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7548:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7549:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7550:          vlv= nbcode[Tvaraff[k]][lv];
                   7551:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7552:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7553:        }
                   7554:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7555:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7556:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7557:        }       
1.264     brouard  7558:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7559:        fprintf(ficgp,"\n#\n");
                   7560:        if(invalidvarcomb[k1]){
                   7561:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7562:          continue;
                   7563:        }
1.227     brouard  7564:       
1.241     brouard  7565:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7566:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7567:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7568: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7569:        k=3;
                   7570:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7571:          if(j==1)
                   7572:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7573:          else
                   7574:            fprintf(ficgp,", '' ");
                   7575:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7576:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7577:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7578:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7579:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7580:        } /* nlstate */
                   7581:        fprintf(ficgp,", '' ");
                   7582:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7583:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7584:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7585:          if(j < nlstate)
                   7586:            fprintf(ficgp,"$%d +",k+l);
                   7587:          else
                   7588:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7589:        }
1.264     brouard  7590:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7591:       } /* end cpt state*/ 
                   7592:     } /* end covariate */  
                   7593:   } /* end nres */
1.227     brouard  7594:   
1.220     brouard  7595: /* 6eme */
1.202     brouard  7596:   /* CV preval stable (period) for each covariate */
1.237     brouard  7597:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7598:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7599:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7600:       continue;
1.255     brouard  7601:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7602:       strcpy(gplotlabel,"(");      
1.288     brouard  7603:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7604:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7605:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7606:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7607:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7608:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7609:        vlv= nbcode[Tvaraff[k]][lv];
                   7610:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7611:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7612:       }
1.237     brouard  7613:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7614:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7615:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7616:       }        
1.264     brouard  7617:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7618:       fprintf(ficgp,"\n#\n");
1.223     brouard  7619:       if(invalidvarcomb[k1]){
1.227     brouard  7620:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7621:        continue;
1.223     brouard  7622:       }
1.227     brouard  7623:       
1.241     brouard  7624:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7625:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7626:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7627: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7628:       k=3; /* Offset */
1.255     brouard  7629:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7630:        if(i==1)
                   7631:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7632:        else
                   7633:          fprintf(ficgp,", '' ");
1.255     brouard  7634:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7635:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7636:        for (j=2; j<= nlstate ; j ++)
                   7637:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7638:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7639:       } /* nlstate */
1.264     brouard  7640:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7641:     } /* end cpt state*/ 
                   7642:   } /* end covariate */  
1.227     brouard  7643:   
                   7644:   
1.220     brouard  7645: /* 7eme */
1.296     brouard  7646:   if(prevbcast == 1){
1.288     brouard  7647:     /* CV backward prevalence  for each covariate */
1.237     brouard  7648:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7649:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7650:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7651:        continue;
1.268     brouard  7652:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7653:        strcpy(gplotlabel,"(");      
1.288     brouard  7654:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7655:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7656:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7657:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7658:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7659:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7660:          vlv= nbcode[Tvaraff[k]][lv];
                   7661:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7662:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7663:        }
1.237     brouard  7664:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7665:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7666:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7667:        }       
1.264     brouard  7668:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7669:        fprintf(ficgp,"\n#\n");
                   7670:        if(invalidvarcomb[k1]){
                   7671:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7672:          continue;
                   7673:        }
                   7674:        
1.241     brouard  7675:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7676:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7677:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7678: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7679:        k=3; /* Offset */
1.268     brouard  7680:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7681:          if(i==1)
                   7682:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7683:          else
                   7684:            fprintf(ficgp,", '' ");
                   7685:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7686:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7687:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7688:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7689:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7690:          /* for (j=2; j<= nlstate ; j ++) */
                   7691:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7692:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7693:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7694:        } /* nlstate */
1.264     brouard  7695:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7696:       } /* end cpt state*/ 
                   7697:     } /* end covariate */  
1.296     brouard  7698:   } /* End if prevbcast */
1.218     brouard  7699:   
1.223     brouard  7700:   /* 8eme */
1.218     brouard  7701:   if(prevfcast==1){
1.288     brouard  7702:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7703:     
1.237     brouard  7704:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7705:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7706:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7707:        continue;
1.211     brouard  7708:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7709:        strcpy(gplotlabel,"(");      
1.288     brouard  7710:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7711:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7712:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7713:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7714:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7715:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7716:          vlv= nbcode[Tvaraff[k]][lv];
                   7717:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7718:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7719:        }
1.237     brouard  7720:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7721:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7722:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7723:        }       
1.264     brouard  7724:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7725:        fprintf(ficgp,"\n#\n");
                   7726:        if(invalidvarcomb[k1]){
                   7727:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7728:          continue;
                   7729:        }
                   7730:        
                   7731:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7732:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7733:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7734:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7735: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7736: 
                   7737:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7738:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7739:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7740:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7741:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7742:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7743:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7744:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7745:          if(i==istart){
1.227     brouard  7746:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7747:          }else{
                   7748:            fprintf(ficgp,",\\\n '' ");
                   7749:          }
                   7750:          if(cptcoveff ==0){ /* No covariate */
                   7751:            ioffset=2; /* Age is in 2 */
                   7752:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7753:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7754:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7755:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7756:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7757:            if(i==nlstate+1){
1.270     brouard  7758:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7759:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7760:              fprintf(ficgp,",\\\n '' ");
                   7761:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7762:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7763:                     offyear,                           \
1.268     brouard  7764:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7765:            }else
1.227     brouard  7766:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7767:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7768:          }else{ /* more than 2 covariates */
1.270     brouard  7769:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7770:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7771:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7772:            iyearc=ioffset-1;
                   7773:            iagec=ioffset;
1.227     brouard  7774:            fprintf(ficgp," u %d:(",ioffset); 
                   7775:            kl=0;
                   7776:            strcpy(gplotcondition,"(");
                   7777:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7778:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7779:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7780:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7781:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7782:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7783:              kl++;
                   7784:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7785:              kl++;
                   7786:              if(k <cptcoveff && cptcoveff>1)
                   7787:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7788:            }
                   7789:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7790:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7791:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7792:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7793:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7794:            if(i==nlstate+1){
1.270     brouard  7795:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7796:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7797:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7798:              fprintf(ficgp," u %d:(",iagec); 
                   7799:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7800:                      iyearc, iagec, offyear,                           \
                   7801:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7802: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7803:            }else{
                   7804:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7805:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7806:            }
                   7807:          } /* end if covariate */
                   7808:        } /* nlstate */
1.264     brouard  7809:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7810:       } /* end cpt state*/
                   7811:     } /* end covariate */
                   7812:   } /* End if prevfcast */
1.227     brouard  7813:   
1.296     brouard  7814:   if(prevbcast==1){
1.268     brouard  7815:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7816:     
                   7817:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7818:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7819:       if(m != 1 && TKresult[nres]!= k1)
                   7820:        continue;
                   7821:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7822:        strcpy(gplotlabel,"(");      
                   7823:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7824:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7825:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7826:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7827:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7828:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7829:          vlv= nbcode[Tvaraff[k]][lv];
                   7830:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7831:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7832:        }
                   7833:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7834:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7835:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7836:        }       
                   7837:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7838:        fprintf(ficgp,"\n#\n");
                   7839:        if(invalidvarcomb[k1]){
                   7840:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7841:          continue;
                   7842:        }
                   7843:        
                   7844:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7845:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7846:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7847:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7848: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7849: 
                   7850:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7851:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7852:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7853:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7854:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7855:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7856:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7857:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7858:          if(i==istart){
                   7859:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7860:          }else{
                   7861:            fprintf(ficgp,",\\\n '' ");
                   7862:          }
                   7863:          if(cptcoveff ==0){ /* No covariate */
                   7864:            ioffset=2; /* Age is in 2 */
                   7865:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7866:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7867:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7868:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7869:            fprintf(ficgp," u %d:(", ioffset); 
                   7870:            if(i==nlstate+1){
1.270     brouard  7871:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7872:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7873:              fprintf(ficgp,",\\\n '' ");
                   7874:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7875:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7876:                     offbyear,                          \
                   7877:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7878:            }else
                   7879:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7880:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7881:          }else{ /* more than 2 covariates */
1.270     brouard  7882:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7883:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7884:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7885:            iyearc=ioffset-1;
                   7886:            iagec=ioffset;
1.268     brouard  7887:            fprintf(ficgp," u %d:(",ioffset); 
                   7888:            kl=0;
                   7889:            strcpy(gplotcondition,"(");
                   7890:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7891:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7892:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7893:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7894:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7895:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7896:              kl++;
                   7897:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7898:              kl++;
                   7899:              if(k <cptcoveff && cptcoveff>1)
                   7900:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7901:            }
                   7902:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7903:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7904:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7905:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7906:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7907:            if(i==nlstate+1){
1.270     brouard  7908:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7909:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7910:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7911:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7912:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7913:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7914:                      iyearc,iagec,offbyear,                            \
                   7915:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7916: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7917:            }else{
                   7918:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7919:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7920:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7921:            }
                   7922:          } /* end if covariate */
                   7923:        } /* nlstate */
                   7924:        fprintf(ficgp,"\nset out; unset label;\n");
                   7925:       } /* end cpt state*/
                   7926:     } /* end covariate */
1.296     brouard  7927:   } /* End if prevbcast */
1.268     brouard  7928:   
1.227     brouard  7929:   
1.238     brouard  7930:   /* 9eme writing MLE parameters */
                   7931:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7932:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7933:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7934:     for(k=1; k <=(nlstate+ndeath); k++){
                   7935:       if (k != i) {
1.227     brouard  7936:        fprintf(ficgp,"#   current state %d\n",k);
                   7937:        for(j=1; j <=ncovmodel; j++){
                   7938:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7939:          jk++; 
                   7940:        }
                   7941:        fprintf(ficgp,"\n");
1.126     brouard  7942:       }
                   7943:     }
1.223     brouard  7944:   }
1.187     brouard  7945:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7946:   
1.145     brouard  7947:   /*goto avoid;*/
1.238     brouard  7948:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7949:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7950:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7951:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7952:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7953:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7954:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7955:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7956:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7957:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7958:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7959:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7960:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7961:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7962:   fprintf(ficgp,"#\n");
1.223     brouard  7963:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  7964:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  7965:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  7966:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  7967:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   7968:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  7969:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  7970:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7971:        continue;
1.264     brouard  7972:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   7973:       strcpy(gplotlabel,"(");
1.276     brouard  7974:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  7975:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7976:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7977:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7978:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7979:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7980:        vlv= nbcode[Tvaraff[k]][lv];
                   7981:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7982:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7983:       }
1.237     brouard  7984:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7985:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7986:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7987:       }        
1.264     brouard  7988:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  7989:       fprintf(ficgp,"\n#\n");
1.264     brouard  7990:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  7991:       fprintf(ficgp,"\nset key outside ");
                   7992:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   7993:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  7994:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   7995:       if (ng==1){
                   7996:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   7997:        fprintf(ficgp,"\nunset log y");
                   7998:       }else if (ng==2){
                   7999:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   8000:        fprintf(ficgp,"\nset log y");
                   8001:       }else if (ng==3){
                   8002:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   8003:        fprintf(ficgp,"\nset log y");
                   8004:       }else
                   8005:        fprintf(ficgp,"\nunset title ");
                   8006:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   8007:       i=1;
                   8008:       for(k2=1; k2<=nlstate; k2++) {
                   8009:        k3=i;
                   8010:        for(k=1; k<=(nlstate+ndeath); k++) {
                   8011:          if (k != k2){
                   8012:            switch( ng) {
                   8013:            case 1:
                   8014:              if(nagesqr==0)
                   8015:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   8016:              else /* nagesqr =1 */
                   8017:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8018:              break;
                   8019:            case 2: /* ng=2 */
                   8020:              if(nagesqr==0)
                   8021:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   8022:              else /* nagesqr =1 */
                   8023:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8024:              break;
                   8025:            case 3:
                   8026:              if(nagesqr==0)
                   8027:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   8028:              else /* nagesqr =1 */
                   8029:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   8030:              break;
                   8031:            }
                   8032:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  8033:            ijp=1; /* product no age */
                   8034:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   8035:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  8036:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  8037:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8038:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   8039:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8040:                    if(DummyV[j]==0){
                   8041:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   8042:                    }else{ /* quantitative */
                   8043:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   8044:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8045:                    }
                   8046:                    ij++;
1.237     brouard  8047:                  }
1.268     brouard  8048:                } 
                   8049:              }else if(cptcovprod >0){
                   8050:                if(j==Tprod[ijp]) { /* */ 
                   8051:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   8052:                  if(ijp <=cptcovprod) { /* Product */
                   8053:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   8054:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   8055:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   8056:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   8057:                      }else{ /* Vn is dummy and Vm is quanti */
                   8058:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   8059:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8060:                      }
                   8061:                    }else{ /* Vn*Vm Vn is quanti */
                   8062:                      if(DummyV[Tvard[ijp][2]]==0){
                   8063:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   8064:                      }else{ /* Both quanti */
                   8065:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8066:                      }
1.237     brouard  8067:                    }
1.268     brouard  8068:                    ijp++;
1.237     brouard  8069:                  }
1.268     brouard  8070:                } /* end Tprod */
1.237     brouard  8071:              } else{  /* simple covariate */
1.264     brouard  8072:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  8073:                if(Dummy[j]==0){
                   8074:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   8075:                }else{ /* quantitative */
                   8076:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  8077:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  8078:                }
1.237     brouard  8079:              } /* end simple */
                   8080:            } /* end j */
1.223     brouard  8081:          }else{
                   8082:            i=i-ncovmodel;
                   8083:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8084:              fprintf(ficgp," (1.");
                   8085:          }
1.227     brouard  8086:          
1.223     brouard  8087:          if(ng != 1){
                   8088:            fprintf(ficgp,")/(1");
1.227     brouard  8089:            
1.264     brouard  8090:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8091:              if(nagesqr==0)
1.264     brouard  8092:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8093:              else /* nagesqr =1 */
1.264     brouard  8094:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8095:               
1.223     brouard  8096:              ij=1;
                   8097:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8098:                 if(cptcovage >0){ 
                   8099:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8100:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8101:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8102:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8103:                       ij++;
                   8104:                     }
                   8105:                   }
                   8106:                 }else
                   8107:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8108:              }
                   8109:              fprintf(ficgp,")");
                   8110:            }
                   8111:            fprintf(ficgp,")");
                   8112:            if(ng ==2)
1.276     brouard  8113:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8114:            else /* ng= 3 */
1.276     brouard  8115:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8116:          }else{ /* end ng <> 1 */
                   8117:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8118:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8119:          }
                   8120:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8121:            fprintf(ficgp,",");
                   8122:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8123:            fprintf(ficgp,",");
                   8124:          i=i+ncovmodel;
                   8125:        } /* end k */
                   8126:       } /* end k2 */
1.276     brouard  8127:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8128:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8129:     } /* end k1 */
1.223     brouard  8130:   } /* end ng */
                   8131:   /* avoid: */
                   8132:   fflush(ficgp); 
1.126     brouard  8133: }  /* end gnuplot */
                   8134: 
                   8135: 
                   8136: /*************** Moving average **************/
1.219     brouard  8137: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8138:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8139:    
1.222     brouard  8140:    int i, cpt, cptcod;
                   8141:    int modcovmax =1;
                   8142:    int mobilavrange, mob;
                   8143:    int iage=0;
1.288     brouard  8144:    int firstA1=0, firstA2=0;
1.222     brouard  8145: 
1.266     brouard  8146:    double sum=0., sumr=0.;
1.222     brouard  8147:    double age;
1.266     brouard  8148:    double *sumnewp, *sumnewm, *sumnewmr;
                   8149:    double *agemingood, *agemaxgood; 
                   8150:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8151:   
                   8152:   
1.278     brouard  8153:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8154:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8155: 
                   8156:    sumnewp = vector(1,ncovcombmax);
                   8157:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8158:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8159:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8160:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8161:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8162:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8163: 
                   8164:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8165:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8166:      sumnewp[cptcod]=0.;
1.266     brouard  8167:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8168:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8169:    }
                   8170:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8171:   
1.266     brouard  8172:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8173:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8174:      else mobilavrange=mobilav;
                   8175:      for (age=bage; age<=fage; age++)
                   8176:        for (i=1; i<=nlstate;i++)
                   8177:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8178:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8179:      /* We keep the original values on the extreme ages bage, fage and for 
                   8180:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8181:        we use a 5 terms etc. until the borders are no more concerned. 
                   8182:      */ 
                   8183:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8184:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8185:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8186:           sumnewm[cptcod]=0.;
                   8187:           for (i=1; i<=nlstate;i++){
1.222     brouard  8188:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8189:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8190:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8191:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8192:             }
                   8193:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8194:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8195:           } /* end i */
                   8196:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8197:         } /* end cptcod */
1.222     brouard  8198:        }/* end age */
                   8199:      }/* end mob */
1.266     brouard  8200:    }else{
                   8201:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8202:      return -1;
1.266     brouard  8203:    }
                   8204: 
                   8205:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8206:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8207:      if(invalidvarcomb[cptcod]){
                   8208:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8209:        continue;
                   8210:      }
1.219     brouard  8211: 
1.266     brouard  8212:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8213:        sumnewm[cptcod]=0.;
                   8214:        sumnewmr[cptcod]=0.;
                   8215:        for (i=1; i<=nlstate;i++){
                   8216:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8217:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8218:        }
                   8219:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8220:         agemingoodr[cptcod]=age;
                   8221:        }
                   8222:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8223:           agemingood[cptcod]=age;
                   8224:        }
                   8225:      } /* age */
                   8226:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8227:        sumnewm[cptcod]=0.;
1.266     brouard  8228:        sumnewmr[cptcod]=0.;
1.222     brouard  8229:        for (i=1; i<=nlstate;i++){
                   8230:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8231:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8232:        }
                   8233:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8234:         agemaxgoodr[cptcod]=age;
1.222     brouard  8235:        }
                   8236:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8237:         agemaxgood[cptcod]=age;
                   8238:        }
                   8239:      } /* age */
                   8240:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8241:      /* but they will change */
1.288     brouard  8242:      firstA1=0;firstA2=0;
1.266     brouard  8243:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8244:        sumnewm[cptcod]=0.;
                   8245:        sumnewmr[cptcod]=0.;
                   8246:        for (i=1; i<=nlstate;i++){
                   8247:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8248:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8249:        }
                   8250:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8251:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8252:           agemaxgoodr[cptcod]=age;  /* age min */
                   8253:           for (i=1; i<=nlstate;i++)
                   8254:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8255:         }else{ /* bad we change the value with the values of good ages */
                   8256:           for (i=1; i<=nlstate;i++){
                   8257:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8258:           } /* i */
                   8259:         } /* end bad */
                   8260:        }else{
                   8261:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8262:           agemaxgood[cptcod]=age;
                   8263:         }else{ /* bad we change the value with the values of good ages */
                   8264:           for (i=1; i<=nlstate;i++){
                   8265:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8266:           } /* i */
                   8267:         } /* end bad */
                   8268:        }/* end else */
                   8269:        sum=0.;sumr=0.;
                   8270:        for (i=1; i<=nlstate;i++){
                   8271:         sum+=mobaverage[(int)age][i][cptcod];
                   8272:         sumr+=probs[(int)age][i][cptcod];
                   8273:        }
                   8274:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8275:         if(!firstA1){
                   8276:           firstA1=1;
                   8277:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8278:         }
                   8279:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8280:        } /* end bad */
                   8281:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8282:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8283:         if(!firstA2){
                   8284:           firstA2=1;
                   8285:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8286:         }
                   8287:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8288:        } /* end bad */
                   8289:      }/* age */
1.266     brouard  8290: 
                   8291:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8292:        sumnewm[cptcod]=0.;
1.266     brouard  8293:        sumnewmr[cptcod]=0.;
1.222     brouard  8294:        for (i=1; i<=nlstate;i++){
                   8295:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8296:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8297:        } 
                   8298:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8299:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8300:           agemingoodr[cptcod]=age;
                   8301:           for (i=1; i<=nlstate;i++)
                   8302:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8303:         }else{ /* bad we change the value with the values of good ages */
                   8304:           for (i=1; i<=nlstate;i++){
                   8305:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8306:           } /* i */
                   8307:         } /* end bad */
                   8308:        }else{
                   8309:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8310:           agemingood[cptcod]=age;
                   8311:         }else{ /* bad */
                   8312:           for (i=1; i<=nlstate;i++){
                   8313:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8314:           } /* i */
                   8315:         } /* end bad */
                   8316:        }/* end else */
                   8317:        sum=0.;sumr=0.;
                   8318:        for (i=1; i<=nlstate;i++){
                   8319:         sum+=mobaverage[(int)age][i][cptcod];
                   8320:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8321:        }
1.266     brouard  8322:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8323:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8324:        } /* end bad */
                   8325:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8326:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8327:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8328:        } /* end bad */
                   8329:      }/* age */
1.266     brouard  8330: 
1.222     brouard  8331:                
                   8332:      for (age=bage; age<=fage; age++){
1.235     brouard  8333:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8334:        sumnewp[cptcod]=0.;
                   8335:        sumnewm[cptcod]=0.;
                   8336:        for (i=1; i<=nlstate;i++){
                   8337:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8338:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8339:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8340:        }
                   8341:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8342:      }
                   8343:      /* printf("\n"); */
                   8344:      /* } */
1.266     brouard  8345: 
1.222     brouard  8346:      /* brutal averaging */
1.266     brouard  8347:      /* for (i=1; i<=nlstate;i++){ */
                   8348:      /*   for (age=1; age<=bage; age++){ */
                   8349:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8350:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8351:      /*   }     */
                   8352:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8353:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8354:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8355:      /*   } */
                   8356:      /* } /\* end i status *\/ */
                   8357:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8358:      /*   for (age=1; age<=AGESUP; age++){ */
                   8359:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8360:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8361:      /*   } */
                   8362:      /* } */
1.222     brouard  8363:    }/* end cptcod */
1.266     brouard  8364:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8365:    free_vector(agemaxgood,1, ncovcombmax);
                   8366:    free_vector(agemingood,1, ncovcombmax);
                   8367:    free_vector(agemingoodr,1, ncovcombmax);
                   8368:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8369:    free_vector(sumnewm,1, ncovcombmax);
                   8370:    free_vector(sumnewp,1, ncovcombmax);
                   8371:    return 0;
                   8372:  }/* End movingaverage */
1.218     brouard  8373:  
1.126     brouard  8374: 
1.296     brouard  8375:  
1.126     brouard  8376: /************** Forecasting ******************/
1.296     brouard  8377: /* void prevforecast(char fileres[], double dateintmean, double anprojd, double mprojd, double jprojd, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anprojf, double p[], int cptcoveff)*/
                   8378: void prevforecast(char fileres[], double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8379:   /* dateintemean, mean date of interviews
                   8380:      dateprojd, year, month, day of starting projection 
                   8381:      dateprojf date of end of projection;year of end of projection (same day and month as proj1).
1.126     brouard  8382:      agemin, agemax range of age
                   8383:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8384:   */
1.296     brouard  8385:   /* double anprojd, mprojd, jprojd; */
                   8386:   /* double anprojf, mprojf, jprojf; */
1.267     brouard  8387:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8388:   double agec; /* generic age */
1.296     brouard  8389:   double agelim, ppij, yp,yp1,yp2;
1.126     brouard  8390:   double *popeffectif,*popcount;
                   8391:   double ***p3mat;
1.218     brouard  8392:   /* double ***mobaverage; */
1.126     brouard  8393:   char fileresf[FILENAMELENGTH];
                   8394: 
                   8395:   agelim=AGESUP;
1.211     brouard  8396:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8397:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8398:      We still use firstpass and lastpass as another selection.
                   8399:   */
1.214     brouard  8400:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8401:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8402:  
1.201     brouard  8403:   strcpy(fileresf,"F_"); 
                   8404:   strcat(fileresf,fileresu);
1.126     brouard  8405:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8406:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8407:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8408:   }
1.235     brouard  8409:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8410:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8411: 
1.225     brouard  8412:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8413: 
                   8414: 
                   8415:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8416:   if (stepm<=12) stepsize=1;
                   8417:   if(estepm < stepm){
                   8418:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8419:   }
1.270     brouard  8420:   else{
                   8421:     hstepm=estepm;   
                   8422:   }
                   8423:   if(estepm > stepm){ /* Yes every two year */
                   8424:     stepsize=2;
                   8425:   }
1.296     brouard  8426:   hstepm=hstepm/stepm;
1.126     brouard  8427: 
1.296     brouard  8428:   
                   8429:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8430:   /*                              fractional in yp1 *\/ */
                   8431:   /* aintmean=yp; */
                   8432:   /* yp2=modf((yp1*12),&yp); */
                   8433:   /* mintmean=yp; */
                   8434:   /* yp1=modf((yp2*30.5),&yp); */
                   8435:   /* jintmean=yp; */
                   8436:   /* if(jintmean==0) jintmean=1; */
                   8437:   /* if(mintmean==0) mintmean=1; */
1.126     brouard  8438: 
1.296     brouard  8439: 
                   8440:   /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */
                   8441:   /* date2dmy(dateprojd,&jprojd, &mprojd, &anprojd); */
                   8442:   /* date2dmy(dateprojf,&jprojf, &mprojf, &anprojf); */
1.227     brouard  8443:   i1=pow(2,cptcoveff);
1.126     brouard  8444:   if (cptcovn < 1){i1=1;}
                   8445:   
1.296     brouard  8446:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2); 
1.126     brouard  8447:   
                   8448:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8449:   
1.126     brouard  8450: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8451:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8452:   for(k=1; k<=i1;k++){
1.253     brouard  8453:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8454:       continue;
1.227     brouard  8455:     if(invalidvarcomb[k]){
                   8456:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8457:       continue;
                   8458:     }
                   8459:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8460:     for(j=1;j<=cptcoveff;j++) {
                   8461:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8462:     }
1.235     brouard  8463:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8464:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8465:     }
1.227     brouard  8466:     fprintf(ficresf," yearproj age");
                   8467:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8468:       for(i=1; i<=nlstate;i++)               
                   8469:        fprintf(ficresf," p%d%d",i,j);
                   8470:       fprintf(ficresf," wp.%d",j);
                   8471:     }
1.296     brouard  8472:     for (yearp=0; yearp<=(anprojf-anprojd);yearp +=stepsize) {
1.227     brouard  8473:       fprintf(ficresf,"\n");
1.296     brouard  8474:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jprojd,mprojd,anprojd+yearp);   
1.270     brouard  8475:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8476:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8477:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8478:        nhstepm = nhstepm/hstepm; 
                   8479:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8480:        oldm=oldms;savm=savms;
1.268     brouard  8481:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8482:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8483:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8484:        for (h=0; h<=nhstepm; h++){
                   8485:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8486:            break;
                   8487:          }
                   8488:        }
                   8489:        fprintf(ficresf,"\n");
                   8490:        for(j=1;j<=cptcoveff;j++) 
                   8491:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8492:        fprintf(ficresf,"%.f %.f ",anprojd+yearp,agec+h*hstepm/YEARM*stepm);
1.268     brouard  8493:        
                   8494:        for(j=1; j<=nlstate+ndeath;j++) {
                   8495:          ppij=0.;
                   8496:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8497:            if (mobilav>=1)
                   8498:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8499:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8500:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8501:            }
1.268     brouard  8502:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8503:          } /* end i */
                   8504:          fprintf(ficresf," %.3f", ppij);
                   8505:        }/* end j */
1.227     brouard  8506:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8507:       } /* end agec */
1.266     brouard  8508:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8509:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8510:     } /* end yearp */
                   8511:   } /* end  k */
1.219     brouard  8512:        
1.126     brouard  8513:   fclose(ficresf);
1.215     brouard  8514:   printf("End of Computing forecasting \n");
                   8515:   fprintf(ficlog,"End of Computing forecasting\n");
                   8516: 
1.126     brouard  8517: }
                   8518: 
1.269     brouard  8519: /************** Back Forecasting ******************/
1.296     brouard  8520:  /* void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
                   8521:  void prevbackforecast(char fileres[], double ***prevacurrent, double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8522:   /* back1, year, month, day of starting backprojection
1.267     brouard  8523:      agemin, agemax range of age
                   8524:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8525:      anback2 year of end of backprojection (same day and month as back1).
                   8526:      prevacurrent and prev are prevalences.
1.267     brouard  8527:   */
                   8528:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8529:   double agec; /* generic age */
1.302     brouard  8530:   double agelim, ppij, ppi, yp,yp1,yp2; /* ,jintmean,mintmean,aintmean;*/
1.267     brouard  8531:   double *popeffectif,*popcount;
                   8532:   double ***p3mat;
                   8533:   /* double ***mobaverage; */
                   8534:   char fileresfb[FILENAMELENGTH];
                   8535:  
1.268     brouard  8536:   agelim=AGEINF;
1.267     brouard  8537:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8538:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8539:      We still use firstpass and lastpass as another selection.
                   8540:   */
                   8541:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8542:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8543: 
                   8544:   /*Do we need to compute prevalence again?*/
                   8545: 
                   8546:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8547:   
                   8548:   strcpy(fileresfb,"FB_");
                   8549:   strcat(fileresfb,fileresu);
                   8550:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8551:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8552:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8553:   }
                   8554:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8555:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8556:   
                   8557:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8558:   
                   8559:    
                   8560:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8561:   if (stepm<=12) stepsize=1;
                   8562:   if(estepm < stepm){
                   8563:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8564:   }
1.270     brouard  8565:   else{
                   8566:     hstepm=estepm;   
                   8567:   }
                   8568:   if(estepm >= stepm){ /* Yes every two year */
                   8569:     stepsize=2;
                   8570:   }
1.267     brouard  8571:   
                   8572:   hstepm=hstepm/stepm;
1.296     brouard  8573:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8574:   /*                              fractional in yp1 *\/ */
                   8575:   /* aintmean=yp; */
                   8576:   /* yp2=modf((yp1*12),&yp); */
                   8577:   /* mintmean=yp; */
                   8578:   /* yp1=modf((yp2*30.5),&yp); */
                   8579:   /* jintmean=yp; */
                   8580:   /* if(jintmean==0) jintmean=1; */
                   8581:   /* if(mintmean==0) jintmean=1; */
1.267     brouard  8582:   
                   8583:   i1=pow(2,cptcoveff);
                   8584:   if (cptcovn < 1){i1=1;}
                   8585:   
1.296     brouard  8586:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
                   8587:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8588:   
                   8589:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8590:   
                   8591:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8592:   for(k=1; k<=i1;k++){
                   8593:     if(i1 != 1 && TKresult[nres]!= k)
                   8594:       continue;
                   8595:     if(invalidvarcomb[k]){
                   8596:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8597:       continue;
                   8598:     }
1.268     brouard  8599:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8600:     for(j=1;j<=cptcoveff;j++) {
                   8601:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8602:     }
                   8603:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8604:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8605:     }
                   8606:     fprintf(ficresfb," yearbproj age");
                   8607:     for(j=1; j<=nlstate+ndeath;j++){
                   8608:       for(i=1; i<=nlstate;i++)
1.268     brouard  8609:        fprintf(ficresfb," b%d%d",i,j);
                   8610:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8611:     }
1.296     brouard  8612:     for (yearp=0; yearp>=(anbackf-anbackd);yearp -=stepsize) {
1.267     brouard  8613:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8614:       fprintf(ficresfb,"\n");
1.296     brouard  8615:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jbackd,mbackd,anbackd+yearp);
1.273     brouard  8616:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8617:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8618:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8619:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8620:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8621:        nhstepm = nhstepm/hstepm;
                   8622:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8623:        oldm=oldms;savm=savms;
1.268     brouard  8624:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8625:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8626:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8627:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8628:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8629:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8630:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8631:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8632:            break;
                   8633:          }
                   8634:        }
                   8635:        fprintf(ficresfb,"\n");
                   8636:        for(j=1;j<=cptcoveff;j++)
                   8637:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8638:        fprintf(ficresfb,"%.f %.f ",anbackd+yearp,agec-h*hstepm/YEARM*stepm);
1.268     brouard  8639:        for(i=1; i<=nlstate+ndeath;i++) {
                   8640:          ppij=0.;ppi=0.;
                   8641:          for(j=1; j<=nlstate;j++) {
                   8642:            /* if (mobilav==1) */
1.269     brouard  8643:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8644:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8645:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8646:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8647:              /* else { */
                   8648:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8649:              /* } */
1.268     brouard  8650:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8651:          } /* end j */
                   8652:          if(ppi <0.99){
                   8653:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8654:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8655:          }
                   8656:          fprintf(ficresfb," %.3f", ppij);
                   8657:        }/* end j */
1.267     brouard  8658:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8659:       } /* end agec */
                   8660:     } /* end yearp */
                   8661:   } /* end k */
1.217     brouard  8662:   
1.267     brouard  8663:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8664:   
1.267     brouard  8665:   fclose(ficresfb);
                   8666:   printf("End of Computing Back forecasting \n");
                   8667:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8668:        
1.267     brouard  8669: }
1.217     brouard  8670: 
1.269     brouard  8671: /* Variance of prevalence limit: varprlim */
                   8672:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8673:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8674:  
                   8675:    char fileresvpl[FILENAMELENGTH];  
                   8676:    FILE *ficresvpl;
                   8677:    double **oldm, **savm;
                   8678:    double **varpl; /* Variances of prevalence limits by age */   
                   8679:    int i1, k, nres, j ;
                   8680:    
                   8681:     strcpy(fileresvpl,"VPL_");
                   8682:     strcat(fileresvpl,fileresu);
                   8683:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8684:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8685:       exit(0);
                   8686:     }
1.288     brouard  8687:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8688:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8689:     
                   8690:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8691:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8692:     
                   8693:     i1=pow(2,cptcoveff);
                   8694:     if (cptcovn < 1){i1=1;}
                   8695: 
                   8696:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8697:     for(k=1; k<=i1;k++){
                   8698:       if(i1 != 1 && TKresult[nres]!= k)
                   8699:        continue;
                   8700:       fprintf(ficresvpl,"\n#****** ");
                   8701:       printf("\n#****** ");
                   8702:       fprintf(ficlog,"\n#****** ");
                   8703:       for(j=1;j<=cptcoveff;j++) {
                   8704:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8705:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8706:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8707:       }
                   8708:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8709:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8710:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8711:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8712:       }        
                   8713:       fprintf(ficresvpl,"******\n");
                   8714:       printf("******\n");
                   8715:       fprintf(ficlog,"******\n");
                   8716:       
                   8717:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8718:       oldm=oldms;savm=savms;
                   8719:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8720:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8721:       /*}*/
                   8722:     }
                   8723:     
                   8724:     fclose(ficresvpl);
1.288     brouard  8725:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   8726:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  8727: 
                   8728:  }
                   8729: /* Variance of back prevalence: varbprlim */
                   8730:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8731:       /*------- Variance of back (stable) prevalence------*/
                   8732: 
                   8733:    char fileresvbl[FILENAMELENGTH];  
                   8734:    FILE  *ficresvbl;
                   8735: 
                   8736:    double **oldm, **savm;
                   8737:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8738:    int i1, k, nres, j ;
                   8739: 
                   8740:    strcpy(fileresvbl,"VBL_");
                   8741:    strcat(fileresvbl,fileresu);
                   8742:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8743:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8744:      exit(0);
                   8745:    }
                   8746:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8747:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8748:    
                   8749:    
                   8750:    i1=pow(2,cptcoveff);
                   8751:    if (cptcovn < 1){i1=1;}
                   8752:    
                   8753:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8754:      for(k=1; k<=i1;k++){
                   8755:        if(i1 != 1 && TKresult[nres]!= k)
                   8756:         continue;
                   8757:        fprintf(ficresvbl,"\n#****** ");
                   8758:        printf("\n#****** ");
                   8759:        fprintf(ficlog,"\n#****** ");
                   8760:        for(j=1;j<=cptcoveff;j++) {
                   8761:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8762:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8763:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8764:        }
                   8765:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8766:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8767:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8768:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8769:        }
                   8770:        fprintf(ficresvbl,"******\n");
                   8771:        printf("******\n");
                   8772:        fprintf(ficlog,"******\n");
                   8773:        
                   8774:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8775:        oldm=oldms;savm=savms;
                   8776:        
                   8777:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8778:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8779:        /*}*/
                   8780:      }
                   8781:    
                   8782:    fclose(ficresvbl);
                   8783:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8784:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8785: 
                   8786:  } /* End of varbprlim */
                   8787: 
1.126     brouard  8788: /************** Forecasting *****not tested NB*************/
1.227     brouard  8789: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8790:   
1.227     brouard  8791: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8792: /*   int *popage; */
                   8793: /*   double calagedatem, agelim, kk1, kk2; */
                   8794: /*   double *popeffectif,*popcount; */
                   8795: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8796: /*   /\* double ***mobaverage; *\/ */
                   8797: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8798: 
1.227     brouard  8799: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8800: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8801: /*   agelim=AGESUP; */
                   8802: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8803:   
1.227     brouard  8804: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8805:   
                   8806:   
1.227     brouard  8807: /*   strcpy(filerespop,"POP_");  */
                   8808: /*   strcat(filerespop,fileresu); */
                   8809: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8810: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8811: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8812: /*   } */
                   8813: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8814: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8815: 
1.227     brouard  8816: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8817: 
1.227     brouard  8818: /*   /\* if (mobilav!=0) { *\/ */
                   8819: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8820: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8821: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8822: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8823: /*   /\*   } *\/ */
                   8824: /*   /\* } *\/ */
1.126     brouard  8825: 
1.227     brouard  8826: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8827: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8828:   
1.227     brouard  8829: /*   agelim=AGESUP; */
1.126     brouard  8830:   
1.227     brouard  8831: /*   hstepm=1; */
                   8832: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8833:        
1.227     brouard  8834: /*   if (popforecast==1) { */
                   8835: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8836: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8837: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8838: /*     }  */
                   8839: /*     popage=ivector(0,AGESUP); */
                   8840: /*     popeffectif=vector(0,AGESUP); */
                   8841: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8842:     
1.227     brouard  8843: /*     i=1;    */
                   8844: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8845:     
1.227     brouard  8846: /*     imx=i; */
                   8847: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8848: /*   } */
1.218     brouard  8849:   
1.227     brouard  8850: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8851: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8852: /*       k=k+1; */
                   8853: /*       fprintf(ficrespop,"\n#******"); */
                   8854: /*       for(j=1;j<=cptcoveff;j++) { */
                   8855: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8856: /*       } */
                   8857: /*       fprintf(ficrespop,"******\n"); */
                   8858: /*       fprintf(ficrespop,"# Age"); */
                   8859: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8860: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8861:       
1.227     brouard  8862: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8863: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8864:        
1.227     brouard  8865: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8866: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8867: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8868:          
1.227     brouard  8869: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8870: /*       oldm=oldms;savm=savms; */
                   8871: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8872:          
1.227     brouard  8873: /*       for (h=0; h<=nhstepm; h++){ */
                   8874: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8875: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8876: /*         }  */
                   8877: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8878: /*           kk1=0.;kk2=0; */
                   8879: /*           for(i=1; i<=nlstate;i++) {               */
                   8880: /*             if (mobilav==1)  */
                   8881: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8882: /*             else { */
                   8883: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8884: /*             } */
                   8885: /*           } */
                   8886: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8887: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8888: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8889: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8890: /*           } */
                   8891: /*         } */
                   8892: /*         for(i=1; i<=nlstate;i++){ */
                   8893: /*           kk1=0.; */
                   8894: /*           for(j=1; j<=nlstate;j++){ */
                   8895: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8896: /*           } */
                   8897: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8898: /*         } */
1.218     brouard  8899:            
1.227     brouard  8900: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8901: /*           for(j=1; j<=nlstate;j++)  */
                   8902: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8903: /*       } */
                   8904: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8905: /*     } */
                   8906: /*       } */
1.218     brouard  8907:       
1.227     brouard  8908: /*       /\******\/ */
1.218     brouard  8909:       
1.227     brouard  8910: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8911: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8912: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8913: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8914: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8915:          
1.227     brouard  8916: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8917: /*       oldm=oldms;savm=savms; */
                   8918: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8919: /*       for (h=0; h<=nhstepm; h++){ */
                   8920: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8921: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8922: /*         }  */
                   8923: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8924: /*           kk1=0.;kk2=0; */
                   8925: /*           for(i=1; i<=nlstate;i++) {               */
                   8926: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8927: /*           } */
                   8928: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8929: /*         } */
                   8930: /*       } */
                   8931: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8932: /*     } */
                   8933: /*       } */
                   8934: /*     }  */
                   8935: /*   } */
1.218     brouard  8936:   
1.227     brouard  8937: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8938:   
1.227     brouard  8939: /*   if (popforecast==1) { */
                   8940: /*     free_ivector(popage,0,AGESUP); */
                   8941: /*     free_vector(popeffectif,0,AGESUP); */
                   8942: /*     free_vector(popcount,0,AGESUP); */
                   8943: /*   } */
                   8944: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8945: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8946: /*   fclose(ficrespop); */
                   8947: /* } /\* End of popforecast *\/ */
1.218     brouard  8948:  
1.126     brouard  8949: int fileappend(FILE *fichier, char *optionfich)
                   8950: {
                   8951:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8952:     printf("Problem with file: %s\n", optionfich);
                   8953:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8954:     return (0);
                   8955:   }
                   8956:   fflush(fichier);
                   8957:   return (1);
                   8958: }
                   8959: 
                   8960: 
                   8961: /**************** function prwizard **********************/
                   8962: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8963: {
                   8964: 
                   8965:   /* Wizard to print covariance matrix template */
                   8966: 
1.164     brouard  8967:   char ca[32], cb[32];
                   8968:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  8969:   int numlinepar;
                   8970: 
                   8971:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8972:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   8973:   for(i=1; i <=nlstate; i++){
                   8974:     jj=0;
                   8975:     for(j=1; j <=nlstate+ndeath; j++){
                   8976:       if(j==i) continue;
                   8977:       jj++;
                   8978:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   8979:       printf("%1d%1d",i,j);
                   8980:       fprintf(ficparo,"%1d%1d",i,j);
                   8981:       for(k=1; k<=ncovmodel;k++){
                   8982:        /*        printf(" %lf",param[i][j][k]); */
                   8983:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   8984:        printf(" 0.");
                   8985:        fprintf(ficparo," 0.");
                   8986:       }
                   8987:       printf("\n");
                   8988:       fprintf(ficparo,"\n");
                   8989:     }
                   8990:   }
                   8991:   printf("# Scales (for hessian or gradient estimation)\n");
                   8992:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   8993:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   8994:   for(i=1; i <=nlstate; i++){
                   8995:     jj=0;
                   8996:     for(j=1; j <=nlstate+ndeath; j++){
                   8997:       if(j==i) continue;
                   8998:       jj++;
                   8999:       fprintf(ficparo,"%1d%1d",i,j);
                   9000:       printf("%1d%1d",i,j);
                   9001:       fflush(stdout);
                   9002:       for(k=1; k<=ncovmodel;k++){
                   9003:        /*      printf(" %le",delti3[i][j][k]); */
                   9004:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   9005:        printf(" 0.");
                   9006:        fprintf(ficparo," 0.");
                   9007:       }
                   9008:       numlinepar++;
                   9009:       printf("\n");
                   9010:       fprintf(ficparo,"\n");
                   9011:     }
                   9012:   }
                   9013:   printf("# Covariance matrix\n");
                   9014: /* # 121 Var(a12)\n\ */
                   9015: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9016: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   9017: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   9018: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   9019: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   9020: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   9021: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   9022:   fflush(stdout);
                   9023:   fprintf(ficparo,"# Covariance matrix\n");
                   9024:   /* # 121 Var(a12)\n\ */
                   9025:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9026:   /* #   ...\n\ */
                   9027:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   9028:   
                   9029:   for(itimes=1;itimes<=2;itimes++){
                   9030:     jj=0;
                   9031:     for(i=1; i <=nlstate; i++){
                   9032:       for(j=1; j <=nlstate+ndeath; j++){
                   9033:        if(j==i) continue;
                   9034:        for(k=1; k<=ncovmodel;k++){
                   9035:          jj++;
                   9036:          ca[0]= k+'a'-1;ca[1]='\0';
                   9037:          if(itimes==1){
                   9038:            printf("#%1d%1d%d",i,j,k);
                   9039:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   9040:          }else{
                   9041:            printf("%1d%1d%d",i,j,k);
                   9042:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   9043:            /*  printf(" %.5le",matcov[i][j]); */
                   9044:          }
                   9045:          ll=0;
                   9046:          for(li=1;li <=nlstate; li++){
                   9047:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   9048:              if(lj==li) continue;
                   9049:              for(lk=1;lk<=ncovmodel;lk++){
                   9050:                ll++;
                   9051:                if(ll<=jj){
                   9052:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   9053:                  if(ll<jj){
                   9054:                    if(itimes==1){
                   9055:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9056:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9057:                    }else{
                   9058:                      printf(" 0.");
                   9059:                      fprintf(ficparo," 0.");
                   9060:                    }
                   9061:                  }else{
                   9062:                    if(itimes==1){
                   9063:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   9064:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   9065:                    }else{
                   9066:                      printf(" 0.");
                   9067:                      fprintf(ficparo," 0.");
                   9068:                    }
                   9069:                  }
                   9070:                }
                   9071:              } /* end lk */
                   9072:            } /* end lj */
                   9073:          } /* end li */
                   9074:          printf("\n");
                   9075:          fprintf(ficparo,"\n");
                   9076:          numlinepar++;
                   9077:        } /* end k*/
                   9078:       } /*end j */
                   9079:     } /* end i */
                   9080:   } /* end itimes */
                   9081: 
                   9082: } /* end of prwizard */
                   9083: /******************* Gompertz Likelihood ******************************/
                   9084: double gompertz(double x[])
                   9085: { 
1.302     brouard  9086:   double A=0.0,B=0.,L=0.0,sump=0.,num=0.;
1.126     brouard  9087:   int i,n=0; /* n is the size of the sample */
                   9088: 
1.220     brouard  9089:   for (i=1;i<=imx ; i++) {
1.126     brouard  9090:     sump=sump+weight[i];
                   9091:     /*    sump=sump+1;*/
                   9092:     num=num+1;
                   9093:   }
1.302     brouard  9094:   L=0.0;
                   9095:   /* agegomp=AGEGOMP; */
1.126     brouard  9096:   /* for (i=0; i<=imx; i++) 
                   9097:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9098: 
1.302     brouard  9099:   for (i=1;i<=imx ; i++) {
                   9100:     /* mu(a)=mu(agecomp)*exp(teta*(age-agegomp))
                   9101:        mu(a)=x[1]*exp(x[2]*(age-agegomp)); x[1] and x[2] are per year.
                   9102:      * L= Product mu(agedeces)exp(-\int_ageexam^agedc mu(u) du ) for a death between agedc (in month) 
                   9103:      *   and agedc +1 month, cens[i]=0: log(x[1]/YEARM)
                   9104:      * +
                   9105:      * exp(-\int_ageexam^agecens mu(u) du ) when censored, cens[i]=1
                   9106:      */
                   9107:      if (wav[i] > 1 || agedc[i] < AGESUP) {
                   9108:        if (cens[i] == 1){
                   9109:         A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9110:        } else if (cens[i] == 0){
1.126     brouard  9111:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
1.302     brouard  9112:          +log(x[1]/YEARM) +x[2]*(agedc[i]-agegomp)+log(YEARM);
                   9113:       } else
                   9114:         printf("Gompertz cens[%d] neither 1 nor 0\n",i);
1.126     brouard  9115:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
1.302     brouard  9116:        L=L+A*weight[i];
1.126     brouard  9117:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
1.302     brouard  9118:      }
                   9119:   }
1.126     brouard  9120: 
1.302     brouard  9121:   /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
1.126     brouard  9122:  
                   9123:   return -2*L*num/sump;
                   9124: }
                   9125: 
1.136     brouard  9126: #ifdef GSL
                   9127: /******************* Gompertz_f Likelihood ******************************/
                   9128: double gompertz_f(const gsl_vector *v, void *params)
                   9129: { 
1.302     brouard  9130:   double A=0.,B=0.,LL=0.0,sump=0.,num=0.;
1.136     brouard  9131:   double *x= (double *) v->data;
                   9132:   int i,n=0; /* n is the size of the sample */
                   9133: 
                   9134:   for (i=0;i<=imx-1 ; i++) {
                   9135:     sump=sump+weight[i];
                   9136:     /*    sump=sump+1;*/
                   9137:     num=num+1;
                   9138:   }
                   9139:  
                   9140:  
                   9141:   /* for (i=0; i<=imx; i++) 
                   9142:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9143:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9144:   for (i=1;i<=imx ; i++)
                   9145:     {
                   9146:       if (cens[i] == 1 && wav[i]>1)
                   9147:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9148:       
                   9149:       if (cens[i] == 0 && wav[i]>1)
                   9150:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9151:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9152:       
                   9153:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9154:       if (wav[i] > 1 ) { /* ??? */
                   9155:        LL=LL+A*weight[i];
                   9156:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9157:       }
                   9158:     }
                   9159: 
                   9160:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9161:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9162:  
                   9163:   return -2*LL*num/sump;
                   9164: }
                   9165: #endif
                   9166: 
1.126     brouard  9167: /******************* Printing html file ***********/
1.201     brouard  9168: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9169:                  int lastpass, int stepm, int weightopt, char model[],\
                   9170:                  int imx,  double p[],double **matcov,double agemortsup){
                   9171:   int i,k;
                   9172: 
                   9173:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9174:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9175:   for (i=1;i<=2;i++) 
                   9176:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9177:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9178:   fprintf(fichtm,"</ul>");
                   9179: 
                   9180: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9181: 
                   9182:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9183: 
                   9184:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9185:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9186: 
                   9187:  
                   9188:   fflush(fichtm);
                   9189: }
                   9190: 
                   9191: /******************* Gnuplot file **************/
1.201     brouard  9192: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9193: 
                   9194:   char dirfileres[132],optfileres[132];
1.164     brouard  9195: 
1.126     brouard  9196:   int ng;
                   9197: 
                   9198: 
                   9199:   /*#ifdef windows */
                   9200:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9201:     /*#endif */
                   9202: 
                   9203: 
                   9204:   strcpy(dirfileres,optionfilefiname);
                   9205:   strcpy(optfileres,"vpl");
1.199     brouard  9206:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9207:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9208:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9209:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9210:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9211: 
                   9212: } 
                   9213: 
1.136     brouard  9214: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9215: {
1.126     brouard  9216: 
1.136     brouard  9217:   /*-------- data file ----------*/
                   9218:   FILE *fic;
                   9219:   char dummy[]="                         ";
1.240     brouard  9220:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9221:   int lstra;
1.136     brouard  9222:   int linei, month, year,iout;
1.302     brouard  9223:   int noffset=0; /* This is the offset if BOM data file */
1.136     brouard  9224:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9225:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9226:   char *stratrunc;
1.223     brouard  9227: 
1.240     brouard  9228:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9229:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9230: 
1.240     brouard  9231:   for(v=1; v <=ncovcol;v++){
                   9232:     DummyV[v]=0;
                   9233:     FixedV[v]=0;
                   9234:   }
                   9235:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9236:     DummyV[v]=1;
                   9237:     FixedV[v]=0;
                   9238:   }
                   9239:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9240:     DummyV[v]=0;
                   9241:     FixedV[v]=1;
                   9242:   }
                   9243:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9244:     DummyV[v]=1;
                   9245:     FixedV[v]=1;
                   9246:   }
                   9247:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9248:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9249:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9250:   }
1.126     brouard  9251: 
1.136     brouard  9252:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9253:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9254:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9255:   }
1.126     brouard  9256: 
1.302     brouard  9257:     /* Is it a BOM UTF-8 Windows file? */
                   9258:   /* First data line */
                   9259:   linei=0;
                   9260:   while(fgets(line, MAXLINE, fic)) {
                   9261:     noffset=0;
                   9262:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   9263:     {
                   9264:       noffset=noffset+3;
                   9265:       printf("# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);fflush(stdout);
                   9266:       fprintf(ficlog,"# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);
                   9267:       fflush(ficlog); return 1;
                   9268:     }
                   9269:     /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   9270:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
                   9271:     {
                   9272:       noffset=noffset+2;
1.304     brouard  9273:       printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9274:       fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9275:       fflush(ficlog); return 1;
                   9276:     }
                   9277:     else if( line[0] == 0 && line[1] == 0)
                   9278:     {
                   9279:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   9280:        noffset=noffset+4;
1.304     brouard  9281:        printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9282:        fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9283:        fflush(ficlog); return 1;
                   9284:       }
                   9285:     } else{
                   9286:       ;/*printf(" Not a BOM file\n");*/
                   9287:     }
                   9288:         /* If line starts with a # it is a comment */
                   9289:     if (line[noffset] == '#') {
                   9290:       linei=linei+1;
                   9291:       break;
                   9292:     }else{
                   9293:       break;
                   9294:     }
                   9295:   }
                   9296:   fclose(fic);
                   9297:   if((fic=fopen(datafile,"r"))==NULL)    {
                   9298:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9299:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
                   9300:   }
                   9301:   /* Not a Bom file */
                   9302:   
1.136     brouard  9303:   i=1;
                   9304:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9305:     linei=linei+1;
                   9306:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9307:       if(line[j] == '\t')
                   9308:        line[j] = ' ';
                   9309:     }
                   9310:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9311:       ;
                   9312:     };
                   9313:     line[j+1]=0;  /* Trims blanks at end of line */
                   9314:     if(line[0]=='#'){
                   9315:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9316:       printf("Comment line\n%s\n",line);
                   9317:       continue;
                   9318:     }
                   9319:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9320:     strcpy(line, linetmp);
1.223     brouard  9321:     
                   9322:     /* Loops on waves */
                   9323:     for (j=maxwav;j>=1;j--){
                   9324:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9325:        cutv(stra, strb, line, ' '); 
                   9326:        if(strb[0]=='.') { /* Missing value */
                   9327:          lval=-1;
                   9328:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9329:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9330:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9331:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9332:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9333:            return 1;
                   9334:          }
                   9335:        }else{
                   9336:          errno=0;
                   9337:          /* what_kind_of_number(strb); */
                   9338:          dval=strtod(strb,&endptr); 
                   9339:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9340:          /* if(strb != endptr && *endptr == '\0') */
                   9341:          /*    dval=dlval; */
                   9342:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9343:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9344:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9345:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9346:            return 1;
                   9347:          }
                   9348:          cotqvar[j][iv][i]=dval; 
                   9349:          cotvar[j][ntv+iv][i]=dval; 
                   9350:        }
                   9351:        strcpy(line,stra);
1.223     brouard  9352:       }/* end loop ntqv */
1.225     brouard  9353:       
1.223     brouard  9354:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9355:        cutv(stra, strb, line, ' '); 
                   9356:        if(strb[0]=='.') { /* Missing value */
                   9357:          lval=-1;
                   9358:        }else{
                   9359:          errno=0;
                   9360:          lval=strtol(strb,&endptr,10); 
                   9361:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9362:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9363:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9364:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9365:            return 1;
                   9366:          }
                   9367:        }
                   9368:        if(lval <-1 || lval >1){
                   9369:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9370:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9371:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9372:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9373:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9374:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9375:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9376:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9377:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9378:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9379:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9380:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9381:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9382:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9383:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9384:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9385:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9386:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9387:          return 1;
                   9388:        }
                   9389:        cotvar[j][iv][i]=(double)(lval);
                   9390:        strcpy(line,stra);
1.223     brouard  9391:       }/* end loop ntv */
1.225     brouard  9392:       
1.223     brouard  9393:       /* Statuses  at wave */
1.137     brouard  9394:       cutv(stra, strb, line, ' '); 
1.223     brouard  9395:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9396:        lval=-1;
1.136     brouard  9397:       }else{
1.238     brouard  9398:        errno=0;
                   9399:        lval=strtol(strb,&endptr,10); 
                   9400:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9401:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9402:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9403:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9404:          return 1;
                   9405:        }
1.136     brouard  9406:       }
1.225     brouard  9407:       
1.136     brouard  9408:       s[j][i]=lval;
1.225     brouard  9409:       
1.223     brouard  9410:       /* Date of Interview */
1.136     brouard  9411:       strcpy(line,stra);
                   9412:       cutv(stra, strb,line,' ');
1.169     brouard  9413:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9414:       }
1.169     brouard  9415:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9416:        month=99;
                   9417:        year=9999;
1.136     brouard  9418:       }else{
1.225     brouard  9419:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9420:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9421:        return 1;
1.136     brouard  9422:       }
                   9423:       anint[j][i]= (double) year; 
1.302     brouard  9424:       mint[j][i]= (double)month;
                   9425:       /* if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){ */
                   9426:       /*       printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9427:       /*       fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9428:       /* } */
1.136     brouard  9429:       strcpy(line,stra);
1.223     brouard  9430:     } /* End loop on waves */
1.225     brouard  9431:     
1.223     brouard  9432:     /* Date of death */
1.136     brouard  9433:     cutv(stra, strb,line,' '); 
1.169     brouard  9434:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9435:     }
1.169     brouard  9436:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9437:       month=99;
                   9438:       year=9999;
                   9439:     }else{
1.141     brouard  9440:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9441:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9442:       return 1;
1.136     brouard  9443:     }
                   9444:     andc[i]=(double) year; 
                   9445:     moisdc[i]=(double) month; 
                   9446:     strcpy(line,stra);
                   9447:     
1.223     brouard  9448:     /* Date of birth */
1.136     brouard  9449:     cutv(stra, strb,line,' '); 
1.169     brouard  9450:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9451:     }
1.169     brouard  9452:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9453:       month=99;
                   9454:       year=9999;
                   9455:     }else{
1.141     brouard  9456:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9457:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9458:       return 1;
1.136     brouard  9459:     }
                   9460:     if (year==9999) {
1.141     brouard  9461:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9462:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9463:       return 1;
                   9464:       
1.136     brouard  9465:     }
                   9466:     annais[i]=(double)(year);
1.302     brouard  9467:     moisnais[i]=(double)(month);
                   9468:     for (j=1;j<=maxwav;j++){
                   9469:       if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){
                   9470:        printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j,(int)moisnais[i],(int)annais[i]);
                   9471:        fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j, (int)moisnais[i],(int)annais[i]);
                   9472:       }
                   9473:     }
                   9474: 
1.136     brouard  9475:     strcpy(line,stra);
1.225     brouard  9476:     
1.223     brouard  9477:     /* Sample weight */
1.136     brouard  9478:     cutv(stra, strb,line,' '); 
                   9479:     errno=0;
                   9480:     dval=strtod(strb,&endptr); 
                   9481:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9482:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9483:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9484:       fflush(ficlog);
                   9485:       return 1;
                   9486:     }
                   9487:     weight[i]=dval; 
                   9488:     strcpy(line,stra);
1.225     brouard  9489:     
1.223     brouard  9490:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9491:       cutv(stra, strb, line, ' '); 
                   9492:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9493:        lval=-1;
1.223     brouard  9494:       }else{
1.225     brouard  9495:        errno=0;
                   9496:        /* what_kind_of_number(strb); */
                   9497:        dval=strtod(strb,&endptr);
                   9498:        /* if(strb != endptr && *endptr == '\0') */
                   9499:        /*   dval=dlval; */
                   9500:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9501:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9502:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9503:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9504:          return 1;
                   9505:        }
                   9506:        coqvar[iv][i]=dval; 
1.226     brouard  9507:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9508:       }
                   9509:       strcpy(line,stra);
                   9510:     }/* end loop nqv */
1.136     brouard  9511:     
1.223     brouard  9512:     /* Covariate values */
1.136     brouard  9513:     for (j=ncovcol;j>=1;j--){
                   9514:       cutv(stra, strb,line,' '); 
1.223     brouard  9515:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9516:        lval=-1;
1.136     brouard  9517:       }else{
1.225     brouard  9518:        errno=0;
                   9519:        lval=strtol(strb,&endptr,10); 
                   9520:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9521:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9522:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9523:          return 1;
                   9524:        }
1.136     brouard  9525:       }
                   9526:       if(lval <-1 || lval >1){
1.225     brouard  9527:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9528:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9529:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9530:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9531:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9532:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9533:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9534:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9535:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9536:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9537:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9538:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9539:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9540:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9541:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9542:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9543:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9544:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9545:        return 1;
1.136     brouard  9546:       }
                   9547:       covar[j][i]=(double)(lval);
                   9548:       strcpy(line,stra);
                   9549:     }  
                   9550:     lstra=strlen(stra);
1.225     brouard  9551:     
1.136     brouard  9552:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9553:       stratrunc = &(stra[lstra-9]);
                   9554:       num[i]=atol(stratrunc);
                   9555:     }
                   9556:     else
                   9557:       num[i]=atol(stra);
                   9558:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9559:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9560:     
                   9561:     i=i+1;
                   9562:   } /* End loop reading  data */
1.225     brouard  9563:   
1.136     brouard  9564:   *imax=i-1; /* Number of individuals */
                   9565:   fclose(fic);
1.225     brouard  9566:   
1.136     brouard  9567:   return (0);
1.164     brouard  9568:   /* endread: */
1.225     brouard  9569:   printf("Exiting readdata: ");
                   9570:   fclose(fic);
                   9571:   return (1);
1.223     brouard  9572: }
1.126     brouard  9573: 
1.234     brouard  9574: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9575:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9576:   while (*p2 == ' ')
1.234     brouard  9577:     p2++; 
                   9578:   /* while ((*p1++ = *p2++) !=0) */
                   9579:   /*   ; */
                   9580:   /* do */
                   9581:   /*   while (*p2 == ' ') */
                   9582:   /*     p2++; */
                   9583:   /* while (*p1++ == *p2++); */
                   9584:   *stri=p2; 
1.145     brouard  9585: }
                   9586: 
1.235     brouard  9587: int decoderesult ( char resultline[], int nres)
1.230     brouard  9588: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9589: {
1.235     brouard  9590:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9591:   char resultsav[MAXLINE];
1.234     brouard  9592:   int resultmodel[MAXLINE];
                   9593:   int modelresult[MAXLINE];
1.230     brouard  9594:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9595: 
1.234     brouard  9596:   removefirstspace(&resultline);
1.230     brouard  9597: 
                   9598:   if (strstr(resultline,"v") !=0){
                   9599:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9600:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9601:     return 1;
                   9602:   }
                   9603:   trimbb(resultsav, resultline);
                   9604:   if (strlen(resultsav) >1){
                   9605:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9606:   }
1.253     brouard  9607:   if(j == 0){ /* Resultline but no = */
                   9608:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9609:     return (0);
                   9610:   }
1.234     brouard  9611:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
                   9612:     printf("ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9613:     fprintf(ficlog,"ERROR: the number of variable in the resultline, %d, differs from the number of variable used in the model line, %d.\n",j, cptcovs);
                   9614:   }
                   9615:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9616:     if(nbocc(resultsav,'=') >1){
                   9617:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
                   9618:                                      resultsav= V4=1 V5=25.1 V3=0 strb=V3=0 stra= V4=1 V5=25.1 */
                   9619:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9620:     }else
                   9621:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9622:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9623:     
1.230     brouard  9624:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9625:     Tvarsel[k]=atoi(strc);
                   9626:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9627:     /* cptcovsel++;     */
                   9628:     if (nbocc(stra,'=') >0)
                   9629:       strcpy(resultsav,stra); /* and analyzes it */
                   9630:   }
1.235     brouard  9631:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9632:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9633:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9634:       match=0;
1.236     brouard  9635:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9636:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9637:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9638:          match=1;
                   9639:          break;
                   9640:        }
                   9641:       }
                   9642:       if(match == 0){
                   9643:        printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9644:       }
                   9645:     }
                   9646:   }
1.235     brouard  9647:   /* Checking for missing or useless values in comparison of current model needs */
                   9648:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9649:     match=0;
1.235     brouard  9650:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9651:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9652:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9653:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9654:          ++match;
                   9655:        }
                   9656:       }
                   9657:     }
                   9658:     if(match == 0){
                   9659:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9660:     }else if(match > 1){
                   9661:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9662:     }
                   9663:   }
1.235     brouard  9664:       
1.234     brouard  9665:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9666:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9667:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9668:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9669:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9670:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9671:   /*    1 0 0 0 */
                   9672:   /*    2 1 0 0 */
                   9673:   /*    3 0 1 0 */ 
                   9674:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9675:   /*    5 0 0 1 */
                   9676:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9677:   /*    7 0 1 1 */
                   9678:   /*    8 1 1 1 */
1.237     brouard  9679:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9680:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9681:   /* V5*age V5 known which value for nres?  */
                   9682:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9683:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9684:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9685:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9686:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9687:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9688:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9689:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9690:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9691:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9692:       k4++;;
                   9693:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9694:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9695:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9696:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9697:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9698:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9699:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9700:       k4q++;;
                   9701:     }
                   9702:   }
1.234     brouard  9703:   
1.235     brouard  9704:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9705:   return (0);
                   9706: }
1.235     brouard  9707: 
1.230     brouard  9708: int decodemodel( char model[], int lastobs)
                   9709:  /**< This routine decodes the model and returns:
1.224     brouard  9710:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9711:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9712:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9713:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9714:        * - cptcovage number of covariates with age*products =2
                   9715:        * - cptcovs number of simple covariates
                   9716:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9717:        *     which is a new column after the 9 (ncovcol) variables. 
                   9718:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9719:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9720:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9721:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9722:        */
1.136     brouard  9723: {
1.238     brouard  9724:   int i, j, k, ks, v;
1.227     brouard  9725:   int  j1, k1, k2, k3, k4;
1.136     brouard  9726:   char modelsav[80];
1.145     brouard  9727:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9728:   char *strpt;
1.136     brouard  9729: 
1.145     brouard  9730:   /*removespace(model);*/
1.136     brouard  9731:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9732:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9733:     if (strstr(model,"AGE") !=0){
1.192     brouard  9734:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9735:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9736:       return 1;
                   9737:     }
1.141     brouard  9738:     if (strstr(model,"v") !=0){
                   9739:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9740:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9741:       return 1;
                   9742:     }
1.187     brouard  9743:     strcpy(modelsav,model); 
                   9744:     if ((strpt=strstr(model,"age*age")) !=0){
                   9745:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9746:       if(strpt != model){
1.234     brouard  9747:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9748:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9749:  corresponding column of parameters.\n",model);
1.234     brouard  9750:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9751:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9752:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9753:        return 1;
1.225     brouard  9754:       }
1.187     brouard  9755:       nagesqr=1;
                   9756:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9757:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9758:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9759:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9760:       else 
1.234     brouard  9761:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9762:     }else
                   9763:       nagesqr=0;
                   9764:     if (strlen(modelsav) >1){
                   9765:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9766:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9767:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9768:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9769:                     * cst, age and age*age 
                   9770:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9771:       /* including age products which are counted in cptcovage.
                   9772:        * but the covariates which are products must be treated 
                   9773:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9774:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9775:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9776:       
                   9777:       
1.187     brouard  9778:       /*   Design
                   9779:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9780:        *  <          ncovcol=8                >
                   9781:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9782:        *   k=  1    2      3       4     5       6      7        8
                   9783:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9784:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9785:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9786:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9787:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9788:        *  Tage[++cptcovage]=k
                   9789:        *       if products, new covar are created after ncovcol with k1
                   9790:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9791:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9792:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9793:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9794:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9795:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9796:        *  <          ncovcol=8                >
                   9797:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9798:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9799:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9800:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9801:        * p Tprod[1]@2={                         6, 5}
                   9802:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9803:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9804:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9805:        *How to reorganize?
                   9806:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9807:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9808:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9809:        * Struct []
                   9810:        */
1.225     brouard  9811:       
1.187     brouard  9812:       /* This loop fills the array Tvar from the string 'model'.*/
                   9813:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9814:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9815:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9816:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9817:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9818:       /*       k=1 Tvar[1]=2 (from V2) */
                   9819:       /*       k=5 Tvar[5] */
                   9820:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9821:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9822:       /*       } */
1.198     brouard  9823:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9824:       /*
                   9825:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9826:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9827:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9828:       }
1.187     brouard  9829:       cptcovage=0;
                   9830:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9831:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9832:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9833:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9834:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9835:        /*scanf("%d",i);*/
                   9836:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9837:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9838:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9839:            /* covar is not filled and then is empty */
                   9840:            cptcovprod--;
                   9841:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9842:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9843:            Typevar[k]=1;  /* 1 for age product */
                   9844:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9845:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9846:            /*printf("stre=%s ", stre);*/
                   9847:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9848:            cptcovprod--;
                   9849:            cutl(stre,strb,strc,'V');
                   9850:            Tvar[k]=atoi(stre);
                   9851:            Typevar[k]=1;  /* 1 for age product */
                   9852:            cptcovage++;
                   9853:            Tage[cptcovage]=k;
                   9854:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9855:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9856:            cptcovn++;
                   9857:            cptcovprodnoage++;k1++;
                   9858:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9859:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9860:                                                because this model-covariate is a construction we invent a new column
                   9861:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9862:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9863:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9864:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9865:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9866:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9867:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9868:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9869:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9870:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9871:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9872:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9873:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9874:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9875:            for (i=1; i<=lastobs;i++){
                   9876:              /* Computes the new covariate which is a product of
                   9877:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9878:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9879:            }
                   9880:          } /* End age is not in the model */
                   9881:        } /* End if model includes a product */
                   9882:        else { /* no more sum */
                   9883:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9884:          /*  scanf("%d",i);*/
                   9885:          cutl(strd,strc,strb,'V');
                   9886:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9887:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9888:          Tvar[k]=atoi(strd);
                   9889:          Typevar[k]=0;  /* 0 for simple covariates */
                   9890:        }
                   9891:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9892:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9893:                                  scanf("%d",i);*/
1.187     brouard  9894:       } /* end of loop + on total covariates */
                   9895:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9896:   } /* end if strlen(model == 0) */
1.136     brouard  9897:   
                   9898:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9899:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9900:   
1.136     brouard  9901:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9902:      printf("cptcovprod=%d ", cptcovprod);
                   9903:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9904:      scanf("%d ",i);*/
                   9905: 
                   9906: 
1.230     brouard  9907: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9908:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9909: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9910:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9911:    k =           1    2   3     4       5       6      7      8        9
                   9912:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9913:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9914:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9915:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9916:          Tmodelind[combination of covar]=k;
1.225     brouard  9917: */  
                   9918: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9919:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9920:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9921:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9922:   printf("Model=%s\n\
                   9923: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9924: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9925: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9926:   fprintf(ficlog,"Model=%s\n\
                   9927: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9928: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9929: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  9930:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9931:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9932:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9933:       Fixed[k]= 0;
                   9934:       Dummy[k]= 0;
1.225     brouard  9935:       ncoveff++;
1.232     brouard  9936:       ncovf++;
1.234     brouard  9937:       nsd++;
                   9938:       modell[k].maintype= FTYPE;
                   9939:       TvarsD[nsd]=Tvar[k];
                   9940:       TvarsDind[nsd]=k;
                   9941:       TvarF[ncovf]=Tvar[k];
                   9942:       TvarFind[ncovf]=k;
                   9943:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9944:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9945:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9946:       Fixed[k]= 0;
                   9947:       Dummy[k]= 0;
                   9948:       ncoveff++;
                   9949:       ncovf++;
                   9950:       modell[k].maintype= FTYPE;
                   9951:       TvarF[ncovf]=Tvar[k];
                   9952:       TvarFind[ncovf]=k;
1.230     brouard  9953:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9954:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9955:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  9956:       Fixed[k]= 0;
                   9957:       Dummy[k]= 1;
1.230     brouard  9958:       nqfveff++;
1.234     brouard  9959:       modell[k].maintype= FTYPE;
                   9960:       modell[k].subtype= FQ;
                   9961:       nsq++;
                   9962:       TvarsQ[nsq]=Tvar[k];
                   9963:       TvarsQind[nsq]=k;
1.232     brouard  9964:       ncovf++;
1.234     brouard  9965:       TvarF[ncovf]=Tvar[k];
                   9966:       TvarFind[ncovf]=k;
1.231     brouard  9967:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  9968:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  9969:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  9970:       Fixed[k]= 1;
                   9971:       Dummy[k]= 0;
1.225     brouard  9972:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  9973:       modell[k].maintype= VTYPE;
                   9974:       modell[k].subtype= VD;
                   9975:       nsd++;
                   9976:       TvarsD[nsd]=Tvar[k];
                   9977:       TvarsDind[nsd]=k;
                   9978:       ncovv++; /* Only simple time varying variables */
                   9979:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9980:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9981:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   9982:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  9983:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   9984:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  9985:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  9986:       Fixed[k]= 1;
                   9987:       Dummy[k]= 1;
                   9988:       nqtveff++;
                   9989:       modell[k].maintype= VTYPE;
                   9990:       modell[k].subtype= VQ;
                   9991:       ncovv++; /* Only simple time varying variables */
                   9992:       nsq++;
                   9993:       TvarsQ[nsq]=Tvar[k];
                   9994:       TvarsQind[nsq]=k;
                   9995:       TvarV[ncovv]=Tvar[k];
1.242     brouard  9996:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  9997:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   9998:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  9999:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   10000:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   10001:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  10002:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  10003:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  10004:       ncova++;
                   10005:       TvarA[ncova]=Tvar[k];
                   10006:       TvarAind[ncova]=k;
1.231     brouard  10007:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  10008:        Fixed[k]= 2;
                   10009:        Dummy[k]= 2;
                   10010:        modell[k].maintype= ATYPE;
                   10011:        modell[k].subtype= APFD;
                   10012:        /* ncoveff++; */
1.227     brouard  10013:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  10014:        Fixed[k]= 2;
                   10015:        Dummy[k]= 3;
                   10016:        modell[k].maintype= ATYPE;
                   10017:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   10018:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  10019:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  10020:        Fixed[k]= 3;
                   10021:        Dummy[k]= 2;
                   10022:        modell[k].maintype= ATYPE;
                   10023:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   10024:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  10025:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10026:        Fixed[k]= 3;
                   10027:        Dummy[k]= 3;
                   10028:        modell[k].maintype= ATYPE;
                   10029:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   10030:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  10031:       }
                   10032:     }else if (Typevar[k] == 2) {  /* product without age */
                   10033:       k1=Tposprod[k];
                   10034:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  10035:        if(Tvard[k1][2] <=ncovcol){
                   10036:          Fixed[k]= 1;
                   10037:          Dummy[k]= 0;
                   10038:          modell[k].maintype= FTYPE;
                   10039:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   10040:          ncovf++; /* Fixed variables without age */
                   10041:          TvarF[ncovf]=Tvar[k];
                   10042:          TvarFind[ncovf]=k;
                   10043:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10044:          Fixed[k]= 0;  /* or 2 ?*/
                   10045:          Dummy[k]= 1;
                   10046:          modell[k].maintype= FTYPE;
                   10047:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   10048:          ncovf++; /* Varying variables without age */
                   10049:          TvarF[ncovf]=Tvar[k];
                   10050:          TvarFind[ncovf]=k;
                   10051:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10052:          Fixed[k]= 1;
                   10053:          Dummy[k]= 0;
                   10054:          modell[k].maintype= VTYPE;
                   10055:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   10056:          ncovv++; /* Varying variables without age */
                   10057:          TvarV[ncovv]=Tvar[k];
                   10058:          TvarVind[ncovv]=k;
                   10059:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10060:          Fixed[k]= 1;
                   10061:          Dummy[k]= 1;
                   10062:          modell[k].maintype= VTYPE;
                   10063:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   10064:          ncovv++; /* Varying variables without age */
                   10065:          TvarV[ncovv]=Tvar[k];
                   10066:          TvarVind[ncovv]=k;
                   10067:        }
1.227     brouard  10068:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  10069:        if(Tvard[k1][2] <=ncovcol){
                   10070:          Fixed[k]= 0;  /* or 2 ?*/
                   10071:          Dummy[k]= 1;
                   10072:          modell[k].maintype= FTYPE;
                   10073:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   10074:          ncovf++; /* Fixed variables without age */
                   10075:          TvarF[ncovf]=Tvar[k];
                   10076:          TvarFind[ncovf]=k;
                   10077:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10078:          Fixed[k]= 1;
                   10079:          Dummy[k]= 1;
                   10080:          modell[k].maintype= VTYPE;
                   10081:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   10082:          ncovv++; /* Varying variables without age */
                   10083:          TvarV[ncovv]=Tvar[k];
                   10084:          TvarVind[ncovv]=k;
                   10085:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10086:          Fixed[k]= 1;
                   10087:          Dummy[k]= 1;
                   10088:          modell[k].maintype= VTYPE;
                   10089:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   10090:          ncovv++; /* Varying variables without age */
                   10091:          TvarV[ncovv]=Tvar[k];
                   10092:          TvarVind[ncovv]=k;
                   10093:          ncovv++; /* Varying variables without age */
                   10094:          TvarV[ncovv]=Tvar[k];
                   10095:          TvarVind[ncovv]=k;
                   10096:        }
1.227     brouard  10097:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  10098:        if(Tvard[k1][2] <=ncovcol){
                   10099:          Fixed[k]= 1;
                   10100:          Dummy[k]= 1;
                   10101:          modell[k].maintype= VTYPE;
                   10102:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   10103:          ncovv++; /* Varying variables without age */
                   10104:          TvarV[ncovv]=Tvar[k];
                   10105:          TvarVind[ncovv]=k;
                   10106:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10107:          Fixed[k]= 1;
                   10108:          Dummy[k]= 1;
                   10109:          modell[k].maintype= VTYPE;
                   10110:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   10111:          ncovv++; /* Varying variables without age */
                   10112:          TvarV[ncovv]=Tvar[k];
                   10113:          TvarVind[ncovv]=k;
                   10114:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10115:          Fixed[k]= 1;
                   10116:          Dummy[k]= 0;
                   10117:          modell[k].maintype= VTYPE;
                   10118:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   10119:          ncovv++; /* Varying variables without age */
                   10120:          TvarV[ncovv]=Tvar[k];
                   10121:          TvarVind[ncovv]=k;
                   10122:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10123:          Fixed[k]= 1;
                   10124:          Dummy[k]= 1;
                   10125:          modell[k].maintype= VTYPE;
                   10126:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   10127:          ncovv++; /* Varying variables without age */
                   10128:          TvarV[ncovv]=Tvar[k];
                   10129:          TvarVind[ncovv]=k;
                   10130:        }
1.227     brouard  10131:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10132:        if(Tvard[k1][2] <=ncovcol){
                   10133:          Fixed[k]= 1;
                   10134:          Dummy[k]= 1;
                   10135:          modell[k].maintype= VTYPE;
                   10136:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   10137:          ncovv++; /* Varying variables without age */
                   10138:          TvarV[ncovv]=Tvar[k];
                   10139:          TvarVind[ncovv]=k;
                   10140:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10141:          Fixed[k]= 1;
                   10142:          Dummy[k]= 1;
                   10143:          modell[k].maintype= VTYPE;
                   10144:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   10145:          ncovv++; /* Varying variables without age */
                   10146:          TvarV[ncovv]=Tvar[k];
                   10147:          TvarVind[ncovv]=k;
                   10148:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10149:          Fixed[k]= 1;
                   10150:          Dummy[k]= 1;
                   10151:          modell[k].maintype= VTYPE;
                   10152:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   10153:          ncovv++; /* Varying variables without age */
                   10154:          TvarV[ncovv]=Tvar[k];
                   10155:          TvarVind[ncovv]=k;
                   10156:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10157:          Fixed[k]= 1;
                   10158:          Dummy[k]= 1;
                   10159:          modell[k].maintype= VTYPE;
                   10160:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10161:          ncovv++; /* Varying variables without age */
                   10162:          TvarV[ncovv]=Tvar[k];
                   10163:          TvarVind[ncovv]=k;
                   10164:        }
1.227     brouard  10165:       }else{
1.240     brouard  10166:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10167:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10168:       } /*end k1*/
1.225     brouard  10169:     }else{
1.226     brouard  10170:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10171:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10172:     }
1.227     brouard  10173:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10174:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10175:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10176:   }
                   10177:   /* Searching for doublons in the model */
                   10178:   for(k1=1; k1<= cptcovt;k1++){
                   10179:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10180:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10181:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10182:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10183:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10184:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10185:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10186:            return(1);
                   10187:          }
                   10188:        }else if (Typevar[k1] ==2){
                   10189:          k3=Tposprod[k1];
                   10190:          k4=Tposprod[k2];
                   10191:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10192:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10193:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10194:            return(1);
                   10195:          }
                   10196:        }
1.227     brouard  10197:       }
                   10198:     }
1.225     brouard  10199:   }
                   10200:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10201:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10202:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10203:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10204:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10205:   /*endread:*/
1.225     brouard  10206:   printf("Exiting decodemodel: ");
                   10207:   return (1);
1.136     brouard  10208: }
                   10209: 
1.169     brouard  10210: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10211: {/* Check ages at death */
1.136     brouard  10212:   int i, m;
1.218     brouard  10213:   int firstone=0;
                   10214:   
1.136     brouard  10215:   for (i=1; i<=imx; i++) {
                   10216:     for(m=2; (m<= maxwav); m++) {
                   10217:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10218:        anint[m][i]=9999;
1.216     brouard  10219:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10220:          s[m][i]=-1;
1.136     brouard  10221:       }
                   10222:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10223:        *nberr = *nberr + 1;
1.218     brouard  10224:        if(firstone == 0){
                   10225:          firstone=1;
1.260     brouard  10226:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10227:        }
1.262     brouard  10228:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10229:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10230:       }
                   10231:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10232:        (*nberr)++;
1.259     brouard  10233:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10234:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10235:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10236:       }
                   10237:     }
                   10238:   }
                   10239: 
                   10240:   for (i=1; i<=imx; i++)  {
                   10241:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10242:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10243:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10244:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10245:          if(agedc[i]>0){
                   10246:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10247:              agev[m][i]=agedc[i];
1.214     brouard  10248:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10249:            }else {
1.136     brouard  10250:              if ((int)andc[i]!=9999){
                   10251:                nbwarn++;
                   10252:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10253:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10254:                agev[m][i]=-1;
                   10255:              }
                   10256:            }
1.169     brouard  10257:          } /* agedc > 0 */
1.214     brouard  10258:        } /* end if */
1.136     brouard  10259:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10260:                                 years but with the precision of a month */
                   10261:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10262:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10263:            agev[m][i]=1;
                   10264:          else if(agev[m][i] < *agemin){ 
                   10265:            *agemin=agev[m][i];
                   10266:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10267:          }
                   10268:          else if(agev[m][i] >*agemax){
                   10269:            *agemax=agev[m][i];
1.156     brouard  10270:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10271:          }
                   10272:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10273:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10274:        } /* en if 9*/
1.136     brouard  10275:        else { /* =9 */
1.214     brouard  10276:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10277:          agev[m][i]=1;
                   10278:          s[m][i]=-1;
                   10279:        }
                   10280:       }
1.214     brouard  10281:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10282:        agev[m][i]=1;
1.214     brouard  10283:       else{
                   10284:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10285:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10286:        agev[m][i]=0;
                   10287:       }
                   10288:     } /* End for lastpass */
                   10289:   }
1.136     brouard  10290:     
                   10291:   for (i=1; i<=imx; i++)  {
                   10292:     for(m=firstpass; (m<=lastpass); m++){
                   10293:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10294:        (*nberr)++;
1.136     brouard  10295:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10296:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10297:        return 1;
                   10298:       }
                   10299:     }
                   10300:   }
                   10301: 
                   10302:   /*for (i=1; i<=imx; i++){
                   10303:   for (m=firstpass; (m<lastpass); m++){
                   10304:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10305: }
                   10306: 
                   10307: }*/
                   10308: 
                   10309: 
1.139     brouard  10310:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10311:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10312: 
                   10313:   return (0);
1.164     brouard  10314:  /* endread:*/
1.136     brouard  10315:     printf("Exiting calandcheckages: ");
                   10316:     return (1);
                   10317: }
                   10318: 
1.172     brouard  10319: #if defined(_MSC_VER)
                   10320: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10321: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10322: //#include "stdafx.h"
                   10323: //#include <stdio.h>
                   10324: //#include <tchar.h>
                   10325: //#include <windows.h>
                   10326: //#include <iostream>
                   10327: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10328: 
                   10329: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10330: 
                   10331: BOOL IsWow64()
                   10332: {
                   10333:        BOOL bIsWow64 = FALSE;
                   10334: 
                   10335:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10336:        //  (HANDLE, PBOOL);
                   10337: 
                   10338:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10339: 
                   10340:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10341:        const char funcName[] = "IsWow64Process";
                   10342:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10343:                GetProcAddress(module, funcName);
                   10344: 
                   10345:        if (NULL != fnIsWow64Process)
                   10346:        {
                   10347:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10348:                        &bIsWow64))
                   10349:                        //throw std::exception("Unknown error");
                   10350:                        printf("Unknown error\n");
                   10351:        }
                   10352:        return bIsWow64 != FALSE;
                   10353: }
                   10354: #endif
1.177     brouard  10355: 
1.191     brouard  10356: void syscompilerinfo(int logged)
1.292     brouard  10357: {
                   10358: #include <stdint.h>
                   10359: 
                   10360:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10361:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10362:    /* /GS /W3 /Gy
                   10363:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10364:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10365:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10366:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10367:    */ 
                   10368:    /* 64 bits */
1.185     brouard  10369:    /*
                   10370:      /GS /W3 /Gy
                   10371:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10372:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10373:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10374:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10375:    /* Optimization are useless and O3 is slower than O2 */
                   10376:    /*
                   10377:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10378:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10379:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10380:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10381:    */
1.186     brouard  10382:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10383:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10384:       /PDB:"visual studio
                   10385:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10386:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10387:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10388:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10389:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10390:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10391:       uiAccess='false'"
                   10392:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10393:       /NOLOGO /TLBID:1
                   10394:    */
1.292     brouard  10395: 
                   10396: 
1.177     brouard  10397: #if defined __INTEL_COMPILER
1.178     brouard  10398: #if defined(__GNUC__)
                   10399:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10400: #endif
1.177     brouard  10401: #elif defined(__GNUC__) 
1.179     brouard  10402: #ifndef  __APPLE__
1.174     brouard  10403: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10404: #endif
1.177     brouard  10405:    struct utsname sysInfo;
1.178     brouard  10406:    int cross = CROSS;
                   10407:    if (cross){
                   10408:           printf("Cross-");
1.191     brouard  10409:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10410:    }
1.174     brouard  10411: #endif
                   10412: 
1.191     brouard  10413:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10414: #if defined(__clang__)
1.191     brouard  10415:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10416: #endif
                   10417: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10418:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10419: #endif
                   10420: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10421:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10422: #endif
                   10423: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10424:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10425: #endif
                   10426: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10427:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10428: #endif
                   10429: #if defined(_MSC_VER)
1.191     brouard  10430:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10431: #endif
                   10432: #if defined(__PGI)
1.191     brouard  10433:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10434: #endif
                   10435: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10436:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10437: #endif
1.191     brouard  10438:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10439:    
1.167     brouard  10440: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10441: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10442:     // Windows (x64 and x86)
1.191     brouard  10443:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10444: #elif __unix__ // all unices, not all compilers
                   10445:     // Unix
1.191     brouard  10446:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10447: #elif __linux__
                   10448:     // linux
1.191     brouard  10449:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10450: #elif __APPLE__
1.174     brouard  10451:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10452:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10453: #endif
                   10454: 
                   10455: /*  __MINGW32__          */
                   10456: /*  __CYGWIN__  */
                   10457: /* __MINGW64__  */
                   10458: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10459: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10460: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10461: /* _WIN64  // Defined for applications for Win64. */
                   10462: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10463: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10464: 
1.167     brouard  10465: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10466:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10467: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10468:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10469: #else
1.191     brouard  10470:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10471: #endif
                   10472: 
1.169     brouard  10473: #if defined(__GNUC__)
                   10474: # if defined(__GNUC_PATCHLEVEL__)
                   10475: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10476:                             + __GNUC_MINOR__ * 100 \
                   10477:                             + __GNUC_PATCHLEVEL__)
                   10478: # else
                   10479: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10480:                             + __GNUC_MINOR__ * 100)
                   10481: # endif
1.174     brouard  10482:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10483:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10484: 
                   10485:    if (uname(&sysInfo) != -1) {
                   10486:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10487:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10488:    }
                   10489:    else
                   10490:       perror("uname() error");
1.179     brouard  10491:    //#ifndef __INTEL_COMPILER 
                   10492: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10493:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10494:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10495: #endif
1.169     brouard  10496: #endif
1.172     brouard  10497: 
1.286     brouard  10498:    //   void main ()
1.172     brouard  10499:    //   {
1.169     brouard  10500: #if defined(_MSC_VER)
1.174     brouard  10501:    if (IsWow64()){
1.191     brouard  10502:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10503:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10504:    }
                   10505:    else{
1.191     brouard  10506:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10507:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10508:    }
1.172     brouard  10509:    //     printf("\nPress Enter to continue...");
                   10510:    //     getchar();
                   10511:    //   }
                   10512: 
1.169     brouard  10513: #endif
                   10514:    
1.167     brouard  10515: 
1.219     brouard  10516: }
1.136     brouard  10517: 
1.219     brouard  10518: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10519:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10520:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10521:   /* double ftolpl = 1.e-10; */
1.180     brouard  10522:   double age, agebase, agelim;
1.203     brouard  10523:   double tot;
1.180     brouard  10524: 
1.202     brouard  10525:   strcpy(filerespl,"PL_");
                   10526:   strcat(filerespl,fileresu);
                   10527:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10528:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10529:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10530:   }
1.288     brouard  10531:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10532:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10533:   pstamp(ficrespl);
1.288     brouard  10534:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10535:   fprintf(ficrespl,"#Age ");
                   10536:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10537:   fprintf(ficrespl,"\n");
1.180     brouard  10538:   
1.219     brouard  10539:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10540: 
1.219     brouard  10541:   agebase=ageminpar;
                   10542:   agelim=agemaxpar;
1.180     brouard  10543: 
1.227     brouard  10544:   /* i1=pow(2,ncoveff); */
1.234     brouard  10545:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10546:   if (cptcovn < 1){i1=1;}
1.180     brouard  10547: 
1.238     brouard  10548:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10549:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10550:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10551:        continue;
1.235     brouard  10552: 
1.238     brouard  10553:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10554:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10555:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10556:       /* k=k+1; */
                   10557:       /* to clean */
                   10558:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10559:       fprintf(ficrespl,"#******");
                   10560:       printf("#******");
                   10561:       fprintf(ficlog,"#******");
                   10562:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10563:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10564:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10565:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10566:       }
                   10567:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10568:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10569:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10570:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10571:       }
                   10572:       fprintf(ficrespl,"******\n");
                   10573:       printf("******\n");
                   10574:       fprintf(ficlog,"******\n");
                   10575:       if(invalidvarcomb[k]){
                   10576:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10577:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10578:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10579:        continue;
                   10580:       }
1.219     brouard  10581: 
1.238     brouard  10582:       fprintf(ficrespl,"#Age ");
                   10583:       for(j=1;j<=cptcoveff;j++) {
                   10584:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10585:       }
                   10586:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10587:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10588:     
1.238     brouard  10589:       for (age=agebase; age<=agelim; age++){
                   10590:        /* for (age=agebase; age<=agebase; age++){ */
                   10591:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10592:        fprintf(ficrespl,"%.0f ",age );
                   10593:        for(j=1;j<=cptcoveff;j++)
                   10594:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10595:        tot=0.;
                   10596:        for(i=1; i<=nlstate;i++){
                   10597:          tot +=  prlim[i][i];
                   10598:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10599:        }
                   10600:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10601:       } /* Age */
                   10602:       /* was end of cptcod */
                   10603:     } /* cptcov */
                   10604:   } /* nres */
1.219     brouard  10605:   return 0;
1.180     brouard  10606: }
                   10607: 
1.218     brouard  10608: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10609:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10610:        
                   10611:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10612:    * at any age between ageminpar and agemaxpar
                   10613:         */
1.235     brouard  10614:   int i, j, k, i1, nres=0 ;
1.217     brouard  10615:   /* double ftolpl = 1.e-10; */
                   10616:   double age, agebase, agelim;
                   10617:   double tot;
1.218     brouard  10618:   /* double ***mobaverage; */
                   10619:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10620: 
                   10621:   strcpy(fileresplb,"PLB_");
                   10622:   strcat(fileresplb,fileresu);
                   10623:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10624:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10625:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10626:   }
1.288     brouard  10627:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10628:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10629:   pstamp(ficresplb);
1.288     brouard  10630:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10631:   fprintf(ficresplb,"#Age ");
                   10632:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10633:   fprintf(ficresplb,"\n");
                   10634:   
1.218     brouard  10635:   
                   10636:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10637:   
                   10638:   agebase=ageminpar;
                   10639:   agelim=agemaxpar;
                   10640:   
                   10641:   
1.227     brouard  10642:   i1=pow(2,cptcoveff);
1.218     brouard  10643:   if (cptcovn < 1){i1=1;}
1.227     brouard  10644:   
1.238     brouard  10645:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10646:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10647:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10648:        continue;
                   10649:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10650:       fprintf(ficresplb,"#******");
                   10651:       printf("#******");
                   10652:       fprintf(ficlog,"#******");
                   10653:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10654:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10655:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10656:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10657:       }
                   10658:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10659:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10660:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10661:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10662:       }
                   10663:       fprintf(ficresplb,"******\n");
                   10664:       printf("******\n");
                   10665:       fprintf(ficlog,"******\n");
                   10666:       if(invalidvarcomb[k]){
                   10667:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10668:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10669:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10670:        continue;
                   10671:       }
1.218     brouard  10672:     
1.238     brouard  10673:       fprintf(ficresplb,"#Age ");
                   10674:       for(j=1;j<=cptcoveff;j++) {
                   10675:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10676:       }
                   10677:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10678:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10679:     
                   10680:     
1.238     brouard  10681:       for (age=agebase; age<=agelim; age++){
                   10682:        /* for (age=agebase; age<=agebase; age++){ */
                   10683:        if(mobilavproj > 0){
                   10684:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10685:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10686:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10687:        }else if (mobilavproj == 0){
                   10688:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10689:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10690:          exit(1);
                   10691:        }else{
                   10692:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10693:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10694:          /* printf("TOTOT\n"); */
                   10695:           /* exit(1); */
1.238     brouard  10696:        }
                   10697:        fprintf(ficresplb,"%.0f ",age );
                   10698:        for(j=1;j<=cptcoveff;j++)
                   10699:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10700:        tot=0.;
                   10701:        for(i=1; i<=nlstate;i++){
                   10702:          tot +=  bprlim[i][i];
                   10703:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10704:        }
                   10705:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10706:       } /* Age */
                   10707:       /* was end of cptcod */
1.255     brouard  10708:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10709:     } /* end of any combination */
                   10710:   } /* end of nres */  
1.218     brouard  10711:   /* hBijx(p, bage, fage); */
                   10712:   /* fclose(ficrespijb); */
                   10713:   
                   10714:   return 0;
1.217     brouard  10715: }
1.218     brouard  10716:  
1.180     brouard  10717: int hPijx(double *p, int bage, int fage){
                   10718:     /*------------- h Pij x at various ages ------------*/
                   10719: 
                   10720:   int stepsize;
                   10721:   int agelim;
                   10722:   int hstepm;
                   10723:   int nhstepm;
1.235     brouard  10724:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10725: 
                   10726:   double agedeb;
                   10727:   double ***p3mat;
                   10728: 
1.201     brouard  10729:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10730:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10731:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10732:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10733:     }
                   10734:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10735:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10736:   
                   10737:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10738:     /*if (stepm<=24) stepsize=2;*/
                   10739: 
                   10740:     agelim=AGESUP;
                   10741:     hstepm=stepsize*YEARM; /* Every year of age */
                   10742:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10743:                
1.180     brouard  10744:     /* hstepm=1;   aff par mois*/
                   10745:     pstamp(ficrespij);
                   10746:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10747:     i1= pow(2,cptcoveff);
1.218     brouard  10748:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10749:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10750:                /*      k=k+1;  */
1.235     brouard  10751:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10752:     for(k=1; k<=i1;k++){
1.253     brouard  10753:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10754:        continue;
1.183     brouard  10755:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10756:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10757:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10758:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10759:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10760:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10761:       }
1.183     brouard  10762:       fprintf(ficrespij,"******\n");
                   10763:       
                   10764:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10765:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10766:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10767:        
                   10768:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10769:        
1.183     brouard  10770:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10771:        oldm=oldms;savm=savms;
1.235     brouard  10772:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10773:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10774:        for(i=1; i<=nlstate;i++)
                   10775:          for(j=1; j<=nlstate+ndeath;j++)
                   10776:            fprintf(ficrespij," %1d-%1d",i,j);
                   10777:        fprintf(ficrespij,"\n");
                   10778:        for (h=0; h<=nhstepm; h++){
                   10779:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10780:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10781:          for(i=1; i<=nlstate;i++)
                   10782:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10783:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10784:          fprintf(ficrespij,"\n");
                   10785:        }
1.183     brouard  10786:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10787:        fprintf(ficrespij,"\n");
                   10788:       }
1.180     brouard  10789:       /*}*/
                   10790:     }
1.218     brouard  10791:     return 0;
1.180     brouard  10792: }
1.218     brouard  10793:  
                   10794:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10795:     /*------------- h Bij x at various ages ------------*/
                   10796: 
                   10797:   int stepsize;
1.218     brouard  10798:   /* int agelim; */
                   10799:        int ageminl;
1.217     brouard  10800:   int hstepm;
                   10801:   int nhstepm;
1.238     brouard  10802:   int h, i, i1, j, k, nres;
1.218     brouard  10803:        
1.217     brouard  10804:   double agedeb;
                   10805:   double ***p3mat;
1.218     brouard  10806:        
                   10807:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10808:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10809:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10810:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10811:   }
                   10812:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10813:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10814:   
                   10815:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10816:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10817:   
1.218     brouard  10818:   /* agelim=AGESUP; */
1.289     brouard  10819:   ageminl=AGEINF; /* was 30 */
1.218     brouard  10820:   hstepm=stepsize*YEARM; /* Every year of age */
                   10821:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10822:   
                   10823:   /* hstepm=1;   aff par mois*/
                   10824:   pstamp(ficrespijb);
1.255     brouard  10825:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10826:   i1= pow(2,cptcoveff);
1.218     brouard  10827:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10828:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10829:   /*   k=k+1;  */
1.238     brouard  10830:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10831:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10832:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10833:        continue;
                   10834:       fprintf(ficrespijb,"\n#****** ");
                   10835:       for(j=1;j<=cptcoveff;j++)
                   10836:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10837:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10838:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10839:       }
                   10840:       fprintf(ficrespijb,"******\n");
1.264     brouard  10841:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10842:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10843:        continue;
                   10844:       }
                   10845:       
                   10846:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10847:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10848:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
1.297     brouard  10849:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm+0.1)-1; /* Typically 20 years = 20*12/6=40 or 55*12/24=27.5-1.1=>27 */
                   10850:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 or 28*/
1.238     brouard  10851:        
                   10852:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10853:        
1.266     brouard  10854:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10855:        /* and memory limitations if stepm is small */
                   10856: 
1.238     brouard  10857:        /* oldm=oldms;savm=savms; */
                   10858:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10859:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10860:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10861:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10862:        for(i=1; i<=nlstate;i++)
                   10863:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10864:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10865:        fprintf(ficrespijb,"\n");
1.238     brouard  10866:        for (h=0; h<=nhstepm; h++){
                   10867:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10868:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10869:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10870:          for(i=1; i<=nlstate;i++)
                   10871:            for(j=1; j<=nlstate+ndeath;j++)
                   10872:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10873:          fprintf(ficrespijb,"\n");
                   10874:        }
                   10875:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10876:        fprintf(ficrespijb,"\n");
                   10877:       } /* end age deb */
                   10878:     } /* end combination */
                   10879:   } /* end nres */
1.218     brouard  10880:   return 0;
                   10881:  } /*  hBijx */
1.217     brouard  10882: 
1.180     brouard  10883: 
1.136     brouard  10884: /***********************************************/
                   10885: /**************** Main Program *****************/
                   10886: /***********************************************/
                   10887: 
                   10888: int main(int argc, char *argv[])
                   10889: {
                   10890: #ifdef GSL
                   10891:   const gsl_multimin_fminimizer_type *T;
                   10892:   size_t iteri = 0, it;
                   10893:   int rval = GSL_CONTINUE;
                   10894:   int status = GSL_SUCCESS;
                   10895:   double ssval;
                   10896: #endif
                   10897:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  10898:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   10899:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  10900:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10901:   int jj, ll, li, lj, lk;
1.136     brouard  10902:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10903:   int num_filled;
1.136     brouard  10904:   int itimes;
                   10905:   int NDIM=2;
                   10906:   int vpopbased=0;
1.235     brouard  10907:   int nres=0;
1.258     brouard  10908:   int endishere=0;
1.277     brouard  10909:   int noffset=0;
1.274     brouard  10910:   int ncurrv=0; /* Temporary variable */
                   10911:   
1.164     brouard  10912:   char ca[32], cb[32];
1.136     brouard  10913:   /*  FILE *fichtm; *//* Html File */
                   10914:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10915:   struct stat info;
1.191     brouard  10916:   double agedeb=0.;
1.194     brouard  10917: 
                   10918:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10919:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10920: 
1.165     brouard  10921:   double fret;
1.191     brouard  10922:   double dum=0.; /* Dummy variable */
1.136     brouard  10923:   double ***p3mat;
1.218     brouard  10924:   /* double ***mobaverage; */
1.164     brouard  10925: 
                   10926:   char line[MAXLINE];
1.197     brouard  10927:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10928: 
1.234     brouard  10929:   char  modeltemp[MAXLINE];
1.230     brouard  10930:   char resultline[MAXLINE];
                   10931:   
1.136     brouard  10932:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10933:   char *tok, *val; /* pathtot */
1.290     brouard  10934:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  10935:   int c,  h , cpt, c2;
1.191     brouard  10936:   int jl=0;
                   10937:   int i1, j1, jk, stepsize=0;
1.194     brouard  10938:   int count=0;
                   10939: 
1.164     brouard  10940:   int *tab; 
1.136     brouard  10941:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.296     brouard  10942:   /* double anprojd, mprojd, jprojd; /\* For eventual projections *\/ */
                   10943:   /* double anprojf, mprojf, jprojf; */
                   10944:   /* double jintmean,mintmean,aintmean;   */
                   10945:   int prvforecast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   10946:   int prvbackcast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   10947:   double yrfproj= 10.0; /* Number of years of forward projections */
                   10948:   double yrbproj= 10.0; /* Number of years of backward projections */
                   10949:   int prevbcast=0; /* defined as global for mlikeli and mle, replacing backcast */
1.136     brouard  10950:   int mobilav=0,popforecast=0;
1.191     brouard  10951:   int hstepm=0, nhstepm=0;
1.136     brouard  10952:   int agemortsup;
                   10953:   float  sumlpop=0.;
                   10954:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10955:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   10956: 
1.191     brouard  10957:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  10958:   double ftolpl=FTOL;
                   10959:   double **prlim;
1.217     brouard  10960:   double **bprlim;
1.136     brouard  10961:   double ***param; /* Matrix of parameters */
1.251     brouard  10962:   double ***paramstart; /* Matrix of starting parameter values */
                   10963:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  10964:   double **matcov; /* Matrix of covariance */
1.203     brouard  10965:   double **hess; /* Hessian matrix */
1.136     brouard  10966:   double ***delti3; /* Scale */
                   10967:   double *delti; /* Scale */
                   10968:   double ***eij, ***vareij;
                   10969:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  10970: 
1.136     brouard  10971:   double *epj, vepp;
1.164     brouard  10972: 
1.273     brouard  10973:   double dateprev1, dateprev2;
1.296     brouard  10974:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0, dateprojd=0, dateprojf=0;
                   10975:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0, datebackd=0, datebackf=0;
                   10976: 
1.217     brouard  10977: 
1.136     brouard  10978:   double **ximort;
1.145     brouard  10979:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  10980:   int *dcwave;
                   10981: 
1.164     brouard  10982:   char z[1]="c";
1.136     brouard  10983: 
                   10984:   /*char  *strt;*/
                   10985:   char strtend[80];
1.126     brouard  10986: 
1.164     brouard  10987: 
1.126     brouard  10988: /*   setlocale (LC_ALL, ""); */
                   10989: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   10990: /*   textdomain (PACKAGE); */
                   10991: /*   setlocale (LC_CTYPE, ""); */
                   10992: /*   setlocale (LC_MESSAGES, ""); */
                   10993: 
                   10994:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  10995:   rstart_time = time(NULL);  
                   10996:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   10997:   start_time = *localtime(&rstart_time);
1.126     brouard  10998:   curr_time=start_time;
1.157     brouard  10999:   /*tml = *localtime(&start_time.tm_sec);*/
                   11000:   /* strcpy(strstart,asctime(&tml)); */
                   11001:   strcpy(strstart,asctime(&start_time));
1.126     brouard  11002: 
                   11003: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  11004: /*  tp.tm_sec = tp.tm_sec +86400; */
                   11005: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  11006: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   11007: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   11008: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  11009: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  11010: /*   strt=asctime(&tmg); */
                   11011: /*   printf("Time(after) =%s",strstart);  */
                   11012: /*  (void) time (&time_value);
                   11013: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   11014: *  tm = *localtime(&time_value);
                   11015: *  strstart=asctime(&tm);
                   11016: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   11017: */
                   11018: 
                   11019:   nberr=0; /* Number of errors and warnings */
                   11020:   nbwarn=0;
1.184     brouard  11021: #ifdef WIN32
                   11022:   _getcwd(pathcd, size);
                   11023: #else
1.126     brouard  11024:   getcwd(pathcd, size);
1.184     brouard  11025: #endif
1.191     brouard  11026:   syscompilerinfo(0);
1.196     brouard  11027:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  11028:   if(argc <=1){
                   11029:     printf("\nEnter the parameter file name: ");
1.205     brouard  11030:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   11031:       printf("ERROR Empty parameter file name\n");
                   11032:       goto end;
                   11033:     }
1.126     brouard  11034:     i=strlen(pathr);
                   11035:     if(pathr[i-1]=='\n')
                   11036:       pathr[i-1]='\0';
1.156     brouard  11037:     i=strlen(pathr);
1.205     brouard  11038:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  11039:       pathr[i-1]='\0';
1.205     brouard  11040:     }
                   11041:     i=strlen(pathr);
                   11042:     if( i==0 ){
                   11043:       printf("ERROR Empty parameter file name\n");
                   11044:       goto end;
                   11045:     }
                   11046:     for (tok = pathr; tok != NULL; ){
1.126     brouard  11047:       printf("Pathr |%s|\n",pathr);
                   11048:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   11049:       printf("val= |%s| pathr=%s\n",val,pathr);
                   11050:       strcpy (pathtot, val);
                   11051:       if(pathr[0] == '\0') break; /* Dirty */
                   11052:     }
                   11053:   }
1.281     brouard  11054:   else if (argc<=2){
                   11055:     strcpy(pathtot,argv[1]);
                   11056:   }
1.126     brouard  11057:   else{
                   11058:     strcpy(pathtot,argv[1]);
1.281     brouard  11059:     strcpy(z,argv[2]);
                   11060:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  11061:   }
                   11062:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   11063:   /*cygwin_split_path(pathtot,path,optionfile);
                   11064:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   11065:   /* cutv(path,optionfile,pathtot,'\\');*/
                   11066: 
                   11067:   /* Split argv[0], imach program to get pathimach */
                   11068:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   11069:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11070:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11071:  /*   strcpy(pathimach,argv[0]); */
                   11072:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   11073:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   11074:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  11075: #ifdef WIN32
                   11076:   _chdir(path); /* Can be a relative path */
                   11077:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   11078: #else
1.126     brouard  11079:   chdir(path); /* Can be a relative path */
1.184     brouard  11080:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   11081: #endif
                   11082:   printf("Current directory %s!\n",pathcd);
1.126     brouard  11083:   strcpy(command,"mkdir ");
                   11084:   strcat(command,optionfilefiname);
                   11085:   if((outcmd=system(command)) != 0){
1.169     brouard  11086:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  11087:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   11088:     /* fclose(ficlog); */
                   11089: /*     exit(1); */
                   11090:   }
                   11091: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   11092: /*     perror("mkdir"); */
                   11093: /*   } */
                   11094: 
                   11095:   /*-------- arguments in the command line --------*/
                   11096: 
1.186     brouard  11097:   /* Main Log file */
1.126     brouard  11098:   strcat(filelog, optionfilefiname);
                   11099:   strcat(filelog,".log");    /* */
                   11100:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   11101:     printf("Problem with logfile %s\n",filelog);
                   11102:     goto end;
                   11103:   }
                   11104:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  11105:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  11106:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   11107:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   11108:  path=%s \n\
                   11109:  optionfile=%s\n\
                   11110:  optionfilext=%s\n\
1.156     brouard  11111:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  11112: 
1.197     brouard  11113:   syscompilerinfo(1);
1.167     brouard  11114: 
1.126     brouard  11115:   printf("Local time (at start):%s",strstart);
                   11116:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   11117:   fflush(ficlog);
                   11118: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  11119: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  11120: 
                   11121:   /* */
                   11122:   strcpy(fileres,"r");
                   11123:   strcat(fileres, optionfilefiname);
1.201     brouard  11124:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  11125:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  11126:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  11127: 
1.186     brouard  11128:   /* Main ---------arguments file --------*/
1.126     brouard  11129: 
                   11130:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  11131:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   11132:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  11133:     fflush(ficlog);
1.149     brouard  11134:     /* goto end; */
                   11135:     exit(70); 
1.126     brouard  11136:   }
                   11137: 
                   11138:   strcpy(filereso,"o");
1.201     brouard  11139:   strcat(filereso,fileresu);
1.126     brouard  11140:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   11141:     printf("Problem with Output resultfile: %s\n", filereso);
                   11142:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   11143:     fflush(ficlog);
                   11144:     goto end;
                   11145:   }
1.278     brouard  11146:       /*-------- Rewriting parameter file ----------*/
                   11147:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   11148:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   11149:   strcat(rfileres,".");    /* */
                   11150:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11151:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   11152:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11153:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   11154:     fflush(ficlog);
                   11155:     goto end;
                   11156:   }
                   11157:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  11158: 
1.278     brouard  11159:                                      
1.126     brouard  11160:   /* Reads comments: lines beginning with '#' */
                   11161:   numlinepar=0;
1.277     brouard  11162:   /* Is it a BOM UTF-8 Windows file? */
                   11163:   /* First parameter line */
1.197     brouard  11164:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11165:     noffset=0;
                   11166:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11167:     {
                   11168:       noffset=noffset+3;
                   11169:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11170:     }
1.302     brouard  11171: /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   11172:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
1.277     brouard  11173:     {
                   11174:       noffset=noffset+2;
                   11175:       printf("# File is an UTF16BE BOM file\n");
                   11176:     }
                   11177:     else if( line[0] == 0 && line[1] == 0)
                   11178:     {
                   11179:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11180:        noffset=noffset+4;
                   11181:        printf("# File is an UTF16BE BOM file\n");
                   11182:       }
                   11183:     } else{
                   11184:       ;/*printf(" Not a BOM file\n");*/
                   11185:     }
                   11186:   
1.197     brouard  11187:     /* If line starts with a # it is a comment */
1.277     brouard  11188:     if (line[noffset] == '#') {
1.197     brouard  11189:       numlinepar++;
                   11190:       fputs(line,stdout);
                   11191:       fputs(line,ficparo);
1.278     brouard  11192:       fputs(line,ficres);
1.197     brouard  11193:       fputs(line,ficlog);
                   11194:       continue;
                   11195:     }else
                   11196:       break;
                   11197:   }
                   11198:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11199:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11200:     if (num_filled != 5) {
                   11201:       printf("Should be 5 parameters\n");
1.283     brouard  11202:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11203:     }
1.126     brouard  11204:     numlinepar++;
1.197     brouard  11205:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11206:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11207:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11208:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11209:   }
                   11210:   /* Second parameter line */
                   11211:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11212:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11213:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11214:     if (line[0] == '#') {
                   11215:       numlinepar++;
1.283     brouard  11216:       printf("%s",line);
                   11217:       fprintf(ficres,"%s",line);
                   11218:       fprintf(ficparo,"%s",line);
                   11219:       fprintf(ficlog,"%s",line);
1.197     brouard  11220:       continue;
                   11221:     }else
                   11222:       break;
                   11223:   }
1.223     brouard  11224:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11225:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11226:     if (num_filled != 11) {
                   11227:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11228:       printf("but line=%s\n",line);
1.283     brouard  11229:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11230:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11231:     }
1.286     brouard  11232:     if( lastpass > maxwav){
                   11233:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11234:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11235:       fflush(ficlog);
                   11236:       goto end;
                   11237:     }
                   11238:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11239:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11240:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11241:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11242:   }
1.203     brouard  11243:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11244:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11245:   /* Third parameter line */
                   11246:   while(fgets(line, MAXLINE, ficpar)) {
                   11247:     /* If line starts with a # it is a comment */
                   11248:     if (line[0] == '#') {
                   11249:       numlinepar++;
1.283     brouard  11250:       printf("%s",line);
                   11251:       fprintf(ficres,"%s",line);
                   11252:       fprintf(ficparo,"%s",line);
                   11253:       fprintf(ficlog,"%s",line);
1.197     brouard  11254:       continue;
                   11255:     }else
                   11256:       break;
                   11257:   }
1.201     brouard  11258:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11259:     if (num_filled != 1){
1.302     brouard  11260:       printf("ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
                   11261:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
1.197     brouard  11262:       model[0]='\0';
                   11263:       goto end;
                   11264:     }
                   11265:     else{
                   11266:       if (model[0]=='+'){
                   11267:        for(i=1; i<=strlen(model);i++)
                   11268:          modeltemp[i-1]=model[i];
1.201     brouard  11269:        strcpy(model,modeltemp); 
1.197     brouard  11270:       }
                   11271:     }
1.199     brouard  11272:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11273:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11274:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11275:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11276:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11277:   }
                   11278:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11279:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11280:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11281:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11282:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11283:   fflush(ficlog);
1.190     brouard  11284:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11285:   if(model[0]=='#'){
1.279     brouard  11286:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11287:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11288:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11289:     if(mle != -1){
1.279     brouard  11290:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11291:       exit(1);
                   11292:     }
                   11293:   }
1.126     brouard  11294:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11295:     ungetc(c,ficpar);
                   11296:     fgets(line, MAXLINE, ficpar);
                   11297:     numlinepar++;
1.195     brouard  11298:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11299:       z[0]=line[1];
                   11300:     }
                   11301:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11302:     fputs(line, stdout);
                   11303:     //puts(line);
1.126     brouard  11304:     fputs(line,ficparo);
                   11305:     fputs(line,ficlog);
                   11306:   }
                   11307:   ungetc(c,ficpar);
                   11308: 
                   11309:    
1.290     brouard  11310:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11311:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11312:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11313:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11314:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11315:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11316:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11317:   */
                   11318:   if (strlen(model)>1) 
1.187     brouard  11319:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11320:   else
1.187     brouard  11321:     ncovmodel=2; /* Constant and age */
1.133     brouard  11322:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11323:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11324:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11325:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11326:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11327:     fflush(stdout);
                   11328:     fclose (ficlog);
                   11329:     goto end;
                   11330:   }
1.126     brouard  11331:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11332:   delti=delti3[1][1];
                   11333:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11334:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11335: /* We could also provide initial parameters values giving by simple logistic regression 
                   11336:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11337:       /* for(i=1;i<nlstate;i++){ */
                   11338:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11339:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11340:       /* } */
1.126     brouard  11341:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11342:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11343:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11344:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11345:     fclose (ficparo);
                   11346:     fclose (ficlog);
                   11347:     goto end;
                   11348:     exit(0);
1.220     brouard  11349:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11350:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11351:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11352:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11353:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11354:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11355:     hess=matrix(1,npar,1,npar);
1.220     brouard  11356:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11357:     /* Read guessed parameters */
1.126     brouard  11358:     /* Reads comments: lines beginning with '#' */
                   11359:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11360:       ungetc(c,ficpar);
                   11361:       fgets(line, MAXLINE, ficpar);
                   11362:       numlinepar++;
1.141     brouard  11363:       fputs(line,stdout);
1.126     brouard  11364:       fputs(line,ficparo);
                   11365:       fputs(line,ficlog);
                   11366:     }
                   11367:     ungetc(c,ficpar);
                   11368:     
                   11369:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11370:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11371:     for(i=1; i <=nlstate; i++){
1.234     brouard  11372:       j=0;
1.126     brouard  11373:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11374:        if(jj==i) continue;
                   11375:        j++;
1.292     brouard  11376:        while((c=getc(ficpar))=='#' && c!= EOF){
                   11377:          ungetc(c,ficpar);
                   11378:          fgets(line, MAXLINE, ficpar);
                   11379:          numlinepar++;
                   11380:          fputs(line,stdout);
                   11381:          fputs(line,ficparo);
                   11382:          fputs(line,ficlog);
                   11383:        }
                   11384:        ungetc(c,ficpar);
1.234     brouard  11385:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11386:        if ((i1 != i) || (j1 != jj)){
                   11387:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11388: It might be a problem of design; if ncovcol and the model are correct\n \
                   11389: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11390:          exit(1);
                   11391:        }
                   11392:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11393:        if(mle==1)
                   11394:          printf("%1d%1d",i,jj);
                   11395:        fprintf(ficlog,"%1d%1d",i,jj);
                   11396:        for(k=1; k<=ncovmodel;k++){
                   11397:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11398:          if(mle==1){
                   11399:            printf(" %lf",param[i][j][k]);
                   11400:            fprintf(ficlog," %lf",param[i][j][k]);
                   11401:          }
                   11402:          else
                   11403:            fprintf(ficlog," %lf",param[i][j][k]);
                   11404:          fprintf(ficparo," %lf",param[i][j][k]);
                   11405:        }
                   11406:        fscanf(ficpar,"\n");
                   11407:        numlinepar++;
                   11408:        if(mle==1)
                   11409:          printf("\n");
                   11410:        fprintf(ficlog,"\n");
                   11411:        fprintf(ficparo,"\n");
1.126     brouard  11412:       }
                   11413:     }  
                   11414:     fflush(ficlog);
1.234     brouard  11415:     
1.251     brouard  11416:     /* Reads parameters values */
1.126     brouard  11417:     p=param[1][1];
1.251     brouard  11418:     pstart=paramstart[1][1];
1.126     brouard  11419:     
                   11420:     /* Reads comments: lines beginning with '#' */
                   11421:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11422:       ungetc(c,ficpar);
                   11423:       fgets(line, MAXLINE, ficpar);
                   11424:       numlinepar++;
1.141     brouard  11425:       fputs(line,stdout);
1.126     brouard  11426:       fputs(line,ficparo);
                   11427:       fputs(line,ficlog);
                   11428:     }
                   11429:     ungetc(c,ficpar);
                   11430: 
                   11431:     for(i=1; i <=nlstate; i++){
                   11432:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11433:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11434:        if ( (i1-i) * (j1-j) != 0){
                   11435:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11436:          exit(1);
                   11437:        }
                   11438:        printf("%1d%1d",i,j);
                   11439:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11440:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11441:        for(k=1; k<=ncovmodel;k++){
                   11442:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11443:          printf(" %le",delti3[i][j][k]);
                   11444:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11445:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11446:        }
                   11447:        fscanf(ficpar,"\n");
                   11448:        numlinepar++;
                   11449:        printf("\n");
                   11450:        fprintf(ficparo,"\n");
                   11451:        fprintf(ficlog,"\n");
1.126     brouard  11452:       }
                   11453:     }
                   11454:     fflush(ficlog);
1.234     brouard  11455:     
1.145     brouard  11456:     /* Reads covariance matrix */
1.126     brouard  11457:     delti=delti3[1][1];
1.220     brouard  11458:                
                   11459:                
1.126     brouard  11460:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11461:                
1.126     brouard  11462:     /* Reads comments: lines beginning with '#' */
                   11463:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11464:       ungetc(c,ficpar);
                   11465:       fgets(line, MAXLINE, ficpar);
                   11466:       numlinepar++;
1.141     brouard  11467:       fputs(line,stdout);
1.126     brouard  11468:       fputs(line,ficparo);
                   11469:       fputs(line,ficlog);
                   11470:     }
                   11471:     ungetc(c,ficpar);
1.220     brouard  11472:                
1.126     brouard  11473:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11474:     hess=matrix(1,npar,1,npar);
1.131     brouard  11475:     for(i=1; i <=npar; i++)
                   11476:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11477:                
1.194     brouard  11478:     /* Scans npar lines */
1.126     brouard  11479:     for(i=1; i <=npar; i++){
1.226     brouard  11480:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11481:       if(count != 3){
1.226     brouard  11482:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11483: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11484: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11485:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11486: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11487: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11488:        exit(1);
1.220     brouard  11489:       }else{
1.226     brouard  11490:        if(mle==1)
                   11491:          printf("%1d%1d%d",i1,j1,jk);
                   11492:       }
                   11493:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11494:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11495:       for(j=1; j <=i; j++){
1.226     brouard  11496:        fscanf(ficpar," %le",&matcov[i][j]);
                   11497:        if(mle==1){
                   11498:          printf(" %.5le",matcov[i][j]);
                   11499:        }
                   11500:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11501:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11502:       }
                   11503:       fscanf(ficpar,"\n");
                   11504:       numlinepar++;
                   11505:       if(mle==1)
1.220     brouard  11506:                                printf("\n");
1.126     brouard  11507:       fprintf(ficlog,"\n");
                   11508:       fprintf(ficparo,"\n");
                   11509:     }
1.194     brouard  11510:     /* End of read covariance matrix npar lines */
1.126     brouard  11511:     for(i=1; i <=npar; i++)
                   11512:       for(j=i+1;j<=npar;j++)
1.226     brouard  11513:        matcov[i][j]=matcov[j][i];
1.126     brouard  11514:     
                   11515:     if(mle==1)
                   11516:       printf("\n");
                   11517:     fprintf(ficlog,"\n");
                   11518:     
                   11519:     fflush(ficlog);
                   11520:     
                   11521:   }    /* End of mle != -3 */
1.218     brouard  11522:   
1.186     brouard  11523:   /*  Main data
                   11524:    */
1.290     brouard  11525:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11526:   /* num=lvector(1,n); */
                   11527:   /* moisnais=vector(1,n); */
                   11528:   /* annais=vector(1,n); */
                   11529:   /* moisdc=vector(1,n); */
                   11530:   /* andc=vector(1,n); */
                   11531:   /* weight=vector(1,n); */
                   11532:   /* agedc=vector(1,n); */
                   11533:   /* cod=ivector(1,n); */
                   11534:   /* for(i=1;i<=n;i++){ */
                   11535:   num=lvector(firstobs,lastobs);
                   11536:   moisnais=vector(firstobs,lastobs);
                   11537:   annais=vector(firstobs,lastobs);
                   11538:   moisdc=vector(firstobs,lastobs);
                   11539:   andc=vector(firstobs,lastobs);
                   11540:   weight=vector(firstobs,lastobs);
                   11541:   agedc=vector(firstobs,lastobs);
                   11542:   cod=ivector(firstobs,lastobs);
                   11543:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11544:     num[i]=0;
                   11545:     moisnais[i]=0;
                   11546:     annais[i]=0;
                   11547:     moisdc[i]=0;
                   11548:     andc[i]=0;
                   11549:     agedc[i]=0;
                   11550:     cod[i]=0;
                   11551:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11552:   }
1.290     brouard  11553:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11554:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11555:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11556:   tab=ivector(1,NCOVMAX);
1.144     brouard  11557:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11558:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11559: 
1.136     brouard  11560:   /* Reads data from file datafile */
                   11561:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11562:     goto end;
                   11563: 
                   11564:   /* Calculation of the number of parameters from char model */
1.234     brouard  11565:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11566:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11567:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11568:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11569:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11570:   */
                   11571:   
                   11572:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11573:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11574:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11575:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11576:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11577:   TvarF=ivector(1,NCOVMAX); /*  */
                   11578:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11579:   TvarV=ivector(1,NCOVMAX); /*  */
                   11580:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11581:   TvarA=ivector(1,NCOVMAX); /*  */
                   11582:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11583:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11584:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11585:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11586:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11587:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11588:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11589:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11590:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11591: 
1.230     brouard  11592:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11593:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11594:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11595:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11596:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11597:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11598:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11599:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11600:   */
                   11601:   /* For model-covariate k tells which data-covariate to use but
                   11602:     because this model-covariate is a construction we invent a new column
                   11603:     ncovcol + k1
                   11604:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11605:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11606:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11607:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11608:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11609:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11610:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11611:   */
1.145     brouard  11612:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11613:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11614:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11615:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11616:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11617:                         4 covariates (3 plus signs)
                   11618:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11619:                      */  
1.230     brouard  11620:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11621:                                * individual dummy, fixed or varying:
                   11622:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11623:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11624:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11625:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11626:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11627:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11628:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11629:                                * individual quantitative, fixed or varying:
                   11630:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11631:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11632:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11633: /* Main decodemodel */
                   11634: 
1.187     brouard  11635: 
1.223     brouard  11636:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11637:     goto end;
                   11638: 
1.137     brouard  11639:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11640:     nbwarn++;
                   11641:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11642:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11643:   }
1.136     brouard  11644:     /*  if(mle==1){*/
1.137     brouard  11645:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11646:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11647:   }
                   11648: 
                   11649:     /*-calculation of age at interview from date of interview and age at death -*/
                   11650:   agev=matrix(1,maxwav,1,imx);
                   11651: 
                   11652:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11653:     goto end;
                   11654: 
1.126     brouard  11655: 
1.136     brouard  11656:   agegomp=(int)agemin;
1.290     brouard  11657:   free_vector(moisnais,firstobs,lastobs);
                   11658:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11659:   /* free_matrix(mint,1,maxwav,1,n);
                   11660:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11661:   /* free_vector(moisdc,1,n); */
                   11662:   /* free_vector(andc,1,n); */
1.145     brouard  11663:   /* */
                   11664:   
1.126     brouard  11665:   wav=ivector(1,imx);
1.214     brouard  11666:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11667:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11668:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11669:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11670:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11671:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11672:    
                   11673:   /* Concatenates waves */
1.214     brouard  11674:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11675:      Death is a valid wave (if date is known).
                   11676:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11677:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11678:      and mw[mi+1][i]. dh depends on stepm.
                   11679:   */
                   11680: 
1.126     brouard  11681:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11682:   /* Concatenates waves */
1.145     brouard  11683:  
1.290     brouard  11684:   free_vector(moisdc,firstobs,lastobs);
                   11685:   free_vector(andc,firstobs,lastobs);
1.215     brouard  11686: 
1.126     brouard  11687:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11688:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11689:   ncodemax[1]=1;
1.145     brouard  11690:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11691:   cptcoveff=0;
1.220     brouard  11692:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11693:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11694:   }
                   11695:   
                   11696:   ncovcombmax=pow(2,cptcoveff);
                   11697:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11698:   for(i=1;i<ncovcombmax;i++)
                   11699:     invalidvarcomb[i]=0;
                   11700:   
1.211     brouard  11701:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11702:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11703:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11704:   
1.200     brouard  11705:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11706:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11707:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11708:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11709:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11710:    * (currently 0 or 1) in the data.
                   11711:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11712:    * corresponding modality (h,j).
                   11713:    */
                   11714: 
1.145     brouard  11715:   h=0;
                   11716:   /*if (cptcovn > 0) */
1.126     brouard  11717:   m=pow(2,cptcoveff);
                   11718:  
1.144     brouard  11719:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11720:           * For k=4 covariates, h goes from 1 to m=2**k
                   11721:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11722:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11723:           *     h\k   1     2     3     4
1.143     brouard  11724:           *______________________________  
                   11725:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11726:           *     2     2     1     1     1
                   11727:           *     3 i=2 1     2     1     1
                   11728:           *     4     2     2     1     1
                   11729:           *     5 i=3 1 i=2 1     2     1
                   11730:           *     6     2     1     2     1
                   11731:           *     7 i=4 1     2     2     1
                   11732:           *     8     2     2     2     1
1.197     brouard  11733:           *     9 i=5 1 i=3 1 i=2 1     2
                   11734:           *    10     2     1     1     2
                   11735:           *    11 i=6 1     2     1     2
                   11736:           *    12     2     2     1     2
                   11737:           *    13 i=7 1 i=4 1     2     2    
                   11738:           *    14     2     1     2     2
                   11739:           *    15 i=8 1     2     2     2
                   11740:           *    16     2     2     2     2
1.143     brouard  11741:           */
1.212     brouard  11742:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11743:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11744:      * and the value of each covariate?
                   11745:      * V1=1, V2=1, V3=2, V4=1 ?
                   11746:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11747:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11748:      * In order to get the real value in the data, we use nbcode
                   11749:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11750:      * We are keeping this crazy system in order to be able (in the future?) 
                   11751:      * to have more than 2 values (0 or 1) for a covariate.
                   11752:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11753:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11754:      *              bbbbbbbb
                   11755:      *              76543210     
                   11756:      *   h-1        00000101 (6-1=5)
1.219     brouard  11757:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11758:      *           &
                   11759:      *     1        00000001 (1)
1.219     brouard  11760:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11761:      *          +1= 00000001 =1 
1.211     brouard  11762:      *
                   11763:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11764:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11765:      *    >>k'            11
                   11766:      *          &   00000001
                   11767:      *            = 00000001
                   11768:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11769:      * Reverse h=6 and m=16?
                   11770:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11771:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11772:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11773:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11774:      * V3=decodtabm(14,3,2**4)=2
                   11775:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11776:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11777:      *          &1 000000001
                   11778:      *           = 000000001
                   11779:      *         +1= 000000010 =2
                   11780:      *                  2211
                   11781:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11782:      *                  V3=2
1.220     brouard  11783:                 * codtabm and decodtabm are identical
1.211     brouard  11784:      */
                   11785: 
1.145     brouard  11786: 
                   11787:  free_ivector(Ndum,-1,NCOVMAX);
                   11788: 
                   11789: 
1.126     brouard  11790:     
1.186     brouard  11791:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11792:   strcpy(optionfilegnuplot,optionfilefiname);
                   11793:   if(mle==-3)
1.201     brouard  11794:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11795:   strcat(optionfilegnuplot,".gp");
                   11796: 
                   11797:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11798:     printf("Problem with file %s",optionfilegnuplot);
                   11799:   }
                   11800:   else{
1.204     brouard  11801:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11802:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11803:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11804:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11805:   }
                   11806:   /*  fclose(ficgp);*/
1.186     brouard  11807: 
                   11808: 
                   11809:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11810: 
                   11811:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11812:   if(mle==-3)
1.201     brouard  11813:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11814:   strcat(optionfilehtm,".htm");
                   11815:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11816:     printf("Problem with %s \n",optionfilehtm);
                   11817:     exit(0);
1.126     brouard  11818:   }
                   11819: 
                   11820:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11821:   strcat(optionfilehtmcov,"-cov.htm");
                   11822:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11823:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11824:   }
                   11825:   else{
                   11826:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11827: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11828: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11829:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11830:   }
                   11831: 
1.213     brouard  11832:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11833: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11834: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11835: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11836: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11837: \n\
                   11838: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11839:  <ul><li><h4>Parameter files</h4>\n\
                   11840:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11841:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11842:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11843:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11844:  - Date and time at start: %s</ul>\n",\
                   11845:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11846:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11847:          fileres,fileres,\
                   11848:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11849:   fflush(fichtm);
                   11850: 
                   11851:   strcpy(pathr,path);
                   11852:   strcat(pathr,optionfilefiname);
1.184     brouard  11853: #ifdef WIN32
                   11854:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11855: #else
1.126     brouard  11856:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11857: #endif
                   11858:          
1.126     brouard  11859:   
1.220     brouard  11860:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11861:                 and for any valid combination of covariates
1.126     brouard  11862:      and prints on file fileres'p'. */
1.251     brouard  11863:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11864:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11865: 
                   11866:   fprintf(fichtm,"\n");
1.286     brouard  11867:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11868:          ftol, stepm);
                   11869:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11870:   ncurrv=1;
                   11871:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11872:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11873:   ncurrv=i;
                   11874:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11875:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  11876:   ncurrv=i;
                   11877:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11878:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  11879:   ncurrv=i;
                   11880:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11881:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11882:           nlstate, ndeath, maxwav, mle, weightopt);
                   11883: 
                   11884:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11885: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11886: 
                   11887:   
                   11888:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11889: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11890: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11891:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11892:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11893:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11894:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11895:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11896:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11897: 
1.126     brouard  11898:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11899:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11900:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11901: 
                   11902:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11903:   /* For mortality only */
1.126     brouard  11904:   if (mle==-3){
1.136     brouard  11905:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11906:     for(i=1;i<=NDIM;i++)
                   11907:       for(j=1;j<=NDIM;j++)
                   11908:        ximort[i][j]=0.;
1.186     brouard  11909:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  11910:     cens=ivector(firstobs,lastobs);
                   11911:     ageexmed=vector(firstobs,lastobs);
                   11912:     agecens=vector(firstobs,lastobs);
                   11913:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  11914:                
1.126     brouard  11915:     for (i=1; i<=imx; i++){
                   11916:       dcwave[i]=-1;
                   11917:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11918:        if (s[m][i]>nlstate) {
                   11919:          dcwave[i]=m;
                   11920:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11921:          break;
                   11922:        }
1.126     brouard  11923:     }
1.226     brouard  11924:     
1.126     brouard  11925:     for (i=1; i<=imx; i++) {
                   11926:       if (wav[i]>0){
1.226     brouard  11927:        ageexmed[i]=agev[mw[1][i]][i];
                   11928:        j=wav[i];
                   11929:        agecens[i]=1.; 
                   11930:        
                   11931:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11932:          agecens[i]=agev[mw[j][i]][i];
                   11933:          cens[i]= 1;
                   11934:        }else if (ageexmed[i]< 1) 
                   11935:          cens[i]= -1;
                   11936:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11937:          cens[i]=0 ;
1.126     brouard  11938:       }
                   11939:       else cens[i]=-1;
                   11940:     }
                   11941:     
                   11942:     for (i=1;i<=NDIM;i++) {
                   11943:       for (j=1;j<=NDIM;j++)
1.226     brouard  11944:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11945:     }
                   11946:     
1.302     brouard  11947:     p[1]=0.0268; p[NDIM]=0.083;
                   11948:     /* printf("%lf %lf", p[1], p[2]); */
1.126     brouard  11949:     
                   11950:     
1.136     brouard  11951: #ifdef GSL
                   11952:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11953: #else
1.126     brouard  11954:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11955: #endif
1.201     brouard  11956:     strcpy(filerespow,"POW-MORT_"); 
                   11957:     strcat(filerespow,fileresu);
1.126     brouard  11958:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   11959:       printf("Problem with resultfile: %s\n", filerespow);
                   11960:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   11961:     }
1.136     brouard  11962: #ifdef GSL
                   11963:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  11964: #else
1.126     brouard  11965:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  11966: #endif
1.126     brouard  11967:     /*  for (i=1;i<=nlstate;i++)
                   11968:        for(j=1;j<=nlstate+ndeath;j++)
                   11969:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   11970:     */
                   11971:     fprintf(ficrespow,"\n");
1.136     brouard  11972: #ifdef GSL
                   11973:     /* gsl starts here */ 
                   11974:     T = gsl_multimin_fminimizer_nmsimplex;
                   11975:     gsl_multimin_fminimizer *sfm = NULL;
                   11976:     gsl_vector *ss, *x;
                   11977:     gsl_multimin_function minex_func;
                   11978: 
                   11979:     /* Initial vertex size vector */
                   11980:     ss = gsl_vector_alloc (NDIM);
                   11981:     
                   11982:     if (ss == NULL){
                   11983:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   11984:     }
                   11985:     /* Set all step sizes to 1 */
                   11986:     gsl_vector_set_all (ss, 0.001);
                   11987: 
                   11988:     /* Starting point */
1.126     brouard  11989:     
1.136     brouard  11990:     x = gsl_vector_alloc (NDIM);
                   11991:     
                   11992:     if (x == NULL){
                   11993:       gsl_vector_free(ss);
                   11994:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   11995:     }
                   11996:   
                   11997:     /* Initialize method and iterate */
                   11998:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  11999:     /*     gsl_vector_set(x, 0, 0.0268); */
                   12000:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  12001:     gsl_vector_set(x, 0, p[1]);
                   12002:     gsl_vector_set(x, 1, p[2]);
                   12003: 
                   12004:     minex_func.f = &gompertz_f;
                   12005:     minex_func.n = NDIM;
                   12006:     minex_func.params = (void *)&p; /* ??? */
                   12007:     
                   12008:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   12009:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   12010:     
                   12011:     printf("Iterations beginning .....\n\n");
                   12012:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   12013: 
                   12014:     iteri=0;
                   12015:     while (rval == GSL_CONTINUE){
                   12016:       iteri++;
                   12017:       status = gsl_multimin_fminimizer_iterate(sfm);
                   12018:       
                   12019:       if (status) printf("error: %s\n", gsl_strerror (status));
                   12020:       fflush(0);
                   12021:       
                   12022:       if (status) 
                   12023:         break;
                   12024:       
                   12025:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   12026:       ssval = gsl_multimin_fminimizer_size (sfm);
                   12027:       
                   12028:       if (rval == GSL_SUCCESS)
                   12029:         printf ("converged to a local maximum at\n");
                   12030:       
                   12031:       printf("%5d ", iteri);
                   12032:       for (it = 0; it < NDIM; it++){
                   12033:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   12034:       }
                   12035:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   12036:     }
                   12037:     
                   12038:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   12039:     
                   12040:     gsl_vector_free(x); /* initial values */
                   12041:     gsl_vector_free(ss); /* inital step size */
                   12042:     for (it=0; it<NDIM; it++){
                   12043:       p[it+1]=gsl_vector_get(sfm->x,it);
                   12044:       fprintf(ficrespow," %.12lf", p[it]);
                   12045:     }
                   12046:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   12047: #endif
                   12048: #ifdef POWELL
                   12049:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   12050: #endif  
1.126     brouard  12051:     fclose(ficrespow);
                   12052:     
1.203     brouard  12053:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  12054: 
                   12055:     for(i=1; i <=NDIM; i++)
                   12056:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  12057:                                matcov[i][j]=matcov[j][i];
1.126     brouard  12058:     
                   12059:     printf("\nCovariance matrix\n ");
1.203     brouard  12060:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  12061:     for(i=1; i <=NDIM; i++) {
                   12062:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  12063:                                printf("%f ",matcov[i][j]);
                   12064:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  12065:       }
1.203     brouard  12066:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  12067:     }
                   12068:     
                   12069:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  12070:     for (i=1;i<=NDIM;i++) {
1.126     brouard  12071:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  12072:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   12073:     }
1.302     brouard  12074:     lsurv=vector(agegomp,AGESUP);
                   12075:     lpop=vector(agegomp,AGESUP);
                   12076:     tpop=vector(agegomp,AGESUP);
1.126     brouard  12077:     lsurv[agegomp]=100000;
                   12078:     
                   12079:     for (k=agegomp;k<=AGESUP;k++) {
                   12080:       agemortsup=k;
                   12081:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   12082:     }
                   12083:     
                   12084:     for (k=agegomp;k<agemortsup;k++)
                   12085:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   12086:     
                   12087:     for (k=agegomp;k<agemortsup;k++){
                   12088:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   12089:       sumlpop=sumlpop+lpop[k];
                   12090:     }
                   12091:     
                   12092:     tpop[agegomp]=sumlpop;
                   12093:     for (k=agegomp;k<(agemortsup-3);k++){
                   12094:       /*  tpop[k+1]=2;*/
                   12095:       tpop[k+1]=tpop[k]-lpop[k];
                   12096:     }
                   12097:     
                   12098:     
                   12099:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   12100:     for (k=agegomp;k<(agemortsup-2);k++) 
                   12101:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   12102:     
                   12103:     
                   12104:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  12105:                ageminpar=50;
                   12106:                agemaxpar=100;
1.194     brouard  12107:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   12108:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12109: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12110: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   12111:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12112: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12113: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12114:     }else{
                   12115:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   12116:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  12117:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  12118:                }
1.201     brouard  12119:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  12120:                     stepm, weightopt,\
                   12121:                     model,imx,p,matcov,agemortsup);
                   12122:     
1.302     brouard  12123:     free_vector(lsurv,agegomp,AGESUP);
                   12124:     free_vector(lpop,agegomp,AGESUP);
                   12125:     free_vector(tpop,agegomp,AGESUP);
1.220     brouard  12126:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  12127:     free_ivector(dcwave,firstobs,lastobs);
                   12128:     free_vector(agecens,firstobs,lastobs);
                   12129:     free_vector(ageexmed,firstobs,lastobs);
                   12130:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  12131: #ifdef GSL
1.136     brouard  12132: #endif
1.186     brouard  12133:   } /* Endof if mle==-3 mortality only */
1.205     brouard  12134:   /* Standard  */
                   12135:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   12136:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12137:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  12138:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  12139:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12140:     for (k=1; k<=npar;k++)
                   12141:       printf(" %d %8.5f",k,p[k]);
                   12142:     printf("\n");
1.205     brouard  12143:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   12144:       /* mlikeli uses func not funcone */
1.247     brouard  12145:       /* for(i=1;i<nlstate;i++){ */
                   12146:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   12147:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   12148:       /* } */
1.205     brouard  12149:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   12150:     }
                   12151:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   12152:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12153:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   12154:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12155:     }
                   12156:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  12157:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12158:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12159:     for (k=1; k<=npar;k++)
                   12160:       printf(" %d %8.5f",k,p[k]);
                   12161:     printf("\n");
                   12162:     
                   12163:     /*--------- results files --------------*/
1.283     brouard  12164:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12165:     
                   12166:     
                   12167:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12168:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12169:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12170:     for(i=1,jk=1; i <=nlstate; i++){
                   12171:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12172:        if (k != i) {
                   12173:          printf("%d%d ",i,k);
                   12174:          fprintf(ficlog,"%d%d ",i,k);
                   12175:          fprintf(ficres,"%1d%1d ",i,k);
                   12176:          for(j=1; j <=ncovmodel; j++){
                   12177:            printf("%12.7f ",p[jk]);
                   12178:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12179:            fprintf(ficres,"%12.7f ",p[jk]);
                   12180:            jk++; 
                   12181:          }
                   12182:          printf("\n");
                   12183:          fprintf(ficlog,"\n");
                   12184:          fprintf(ficres,"\n");
                   12185:        }
1.126     brouard  12186:       }
                   12187:     }
1.203     brouard  12188:     if(mle != 0){
                   12189:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12190:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12191:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12192:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12193:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12194:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12195:        for(k=1; k <=(nlstate+ndeath); k++){
                   12196:          if (k != i) {
                   12197:            printf("%d%d ",i,k);
                   12198:            fprintf(ficlog,"%d%d ",i,k);
                   12199:            for(j=1; j <=ncovmodel; j++){
                   12200:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12201:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12202:              jk++; 
                   12203:            }
                   12204:            printf("\n");
                   12205:            fprintf(ficlog,"\n");
                   12206:          }
                   12207:        }
1.193     brouard  12208:       }
1.203     brouard  12209:     } /* end of hesscov and Wald tests */
1.225     brouard  12210:     
1.203     brouard  12211:     /*  */
1.126     brouard  12212:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12213:     printf("# Scales (for hessian or gradient estimation)\n");
                   12214:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12215:     for(i=1,jk=1; i <=nlstate; i++){
                   12216:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12217:        if (j!=i) {
                   12218:          fprintf(ficres,"%1d%1d",i,j);
                   12219:          printf("%1d%1d",i,j);
                   12220:          fprintf(ficlog,"%1d%1d",i,j);
                   12221:          for(k=1; k<=ncovmodel;k++){
                   12222:            printf(" %.5e",delti[jk]);
                   12223:            fprintf(ficlog," %.5e",delti[jk]);
                   12224:            fprintf(ficres," %.5e",delti[jk]);
                   12225:            jk++;
                   12226:          }
                   12227:          printf("\n");
                   12228:          fprintf(ficlog,"\n");
                   12229:          fprintf(ficres,"\n");
                   12230:        }
1.126     brouard  12231:       }
                   12232:     }
                   12233:     
                   12234:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12235:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12236:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12237:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12238:     /* # 121 Var(a12)\n\ */
                   12239:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12240:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12241:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12242:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12243:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12244:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12245:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12246:     
                   12247:     
                   12248:     /* Just to have a covariance matrix which will be more understandable
                   12249:        even is we still don't want to manage dictionary of variables
                   12250:     */
                   12251:     for(itimes=1;itimes<=2;itimes++){
                   12252:       jj=0;
                   12253:       for(i=1; i <=nlstate; i++){
1.225     brouard  12254:        for(j=1; j <=nlstate+ndeath; j++){
                   12255:          if(j==i) continue;
                   12256:          for(k=1; k<=ncovmodel;k++){
                   12257:            jj++;
                   12258:            ca[0]= k+'a'-1;ca[1]='\0';
                   12259:            if(itimes==1){
                   12260:              if(mle>=1)
                   12261:                printf("#%1d%1d%d",i,j,k);
                   12262:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12263:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12264:            }else{
                   12265:              if(mle>=1)
                   12266:                printf("%1d%1d%d",i,j,k);
                   12267:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12268:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12269:            }
                   12270:            ll=0;
                   12271:            for(li=1;li <=nlstate; li++){
                   12272:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12273:                if(lj==li) continue;
                   12274:                for(lk=1;lk<=ncovmodel;lk++){
                   12275:                  ll++;
                   12276:                  if(ll<=jj){
                   12277:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12278:                    if(ll<jj){
                   12279:                      if(itimes==1){
                   12280:                        if(mle>=1)
                   12281:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12282:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12283:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12284:                      }else{
                   12285:                        if(mle>=1)
                   12286:                          printf(" %.5e",matcov[jj][ll]); 
                   12287:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12288:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12289:                      }
                   12290:                    }else{
                   12291:                      if(itimes==1){
                   12292:                        if(mle>=1)
                   12293:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12294:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12295:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12296:                      }else{
                   12297:                        if(mle>=1)
                   12298:                          printf(" %.7e",matcov[jj][ll]); 
                   12299:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12300:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12301:                      }
                   12302:                    }
                   12303:                  }
                   12304:                } /* end lk */
                   12305:              } /* end lj */
                   12306:            } /* end li */
                   12307:            if(mle>=1)
                   12308:              printf("\n");
                   12309:            fprintf(ficlog,"\n");
                   12310:            fprintf(ficres,"\n");
                   12311:            numlinepar++;
                   12312:          } /* end k*/
                   12313:        } /*end j */
1.126     brouard  12314:       } /* end i */
                   12315:     } /* end itimes */
                   12316:     
                   12317:     fflush(ficlog);
                   12318:     fflush(ficres);
1.225     brouard  12319:     while(fgets(line, MAXLINE, ficpar)) {
                   12320:       /* If line starts with a # it is a comment */
                   12321:       if (line[0] == '#') {
                   12322:        numlinepar++;
                   12323:        fputs(line,stdout);
                   12324:        fputs(line,ficparo);
                   12325:        fputs(line,ficlog);
1.299     brouard  12326:        fputs(line,ficres);
1.225     brouard  12327:        continue;
                   12328:       }else
                   12329:        break;
                   12330:     }
                   12331:     
1.209     brouard  12332:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12333:     /*   ungetc(c,ficpar); */
                   12334:     /*   fgets(line, MAXLINE, ficpar); */
                   12335:     /*   fputs(line,stdout); */
                   12336:     /*   fputs(line,ficparo); */
                   12337:     /* } */
                   12338:     /* ungetc(c,ficpar); */
1.126     brouard  12339:     
                   12340:     estepm=0;
1.209     brouard  12341:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12342:       
                   12343:       if (num_filled != 6) {
                   12344:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12345:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12346:        goto end;
                   12347:       }
                   12348:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12349:     }
                   12350:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12351:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12352:     
1.209     brouard  12353:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12354:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12355:     if (fage <= 2) {
                   12356:       bage = ageminpar;
                   12357:       fage = agemaxpar;
                   12358:     }
                   12359:     
                   12360:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12361:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12362:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12363:                
1.186     brouard  12364:     /* Other stuffs, more or less useful */    
1.254     brouard  12365:     while(fgets(line, MAXLINE, ficpar)) {
                   12366:       /* If line starts with a # it is a comment */
                   12367:       if (line[0] == '#') {
                   12368:        numlinepar++;
                   12369:        fputs(line,stdout);
                   12370:        fputs(line,ficparo);
                   12371:        fputs(line,ficlog);
1.299     brouard  12372:        fputs(line,ficres);
1.254     brouard  12373:        continue;
                   12374:       }else
                   12375:        break;
                   12376:     }
                   12377: 
                   12378:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12379:       
                   12380:       if (num_filled != 7) {
                   12381:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12382:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12383:        goto end;
                   12384:       }
                   12385:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12386:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12387:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12388:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12389:     }
1.254     brouard  12390: 
                   12391:     while(fgets(line, MAXLINE, ficpar)) {
                   12392:       /* If line starts with a # it is a comment */
                   12393:       if (line[0] == '#') {
                   12394:        numlinepar++;
                   12395:        fputs(line,stdout);
                   12396:        fputs(line,ficparo);
                   12397:        fputs(line,ficlog);
1.299     brouard  12398:        fputs(line,ficres);
1.254     brouard  12399:        continue;
                   12400:       }else
                   12401:        break;
1.126     brouard  12402:     }
                   12403:     
                   12404:     
                   12405:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12406:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12407:     
1.254     brouard  12408:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12409:       if (num_filled != 1) {
                   12410:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12411:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12412:        goto end;
                   12413:       }
                   12414:       printf("pop_based=%d\n",popbased);
                   12415:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12416:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12417:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12418:     }
                   12419:      
1.258     brouard  12420:     /* Results */
1.307     brouard  12421:     endishere=0;
1.258     brouard  12422:     nresult=0;
1.308   ! brouard  12423:     parameterline=0;
1.258     brouard  12424:     do{
                   12425:       if(!fgets(line, MAXLINE, ficpar)){
                   12426:        endishere=1;
1.308   ! brouard  12427:        parameterline=15;
1.258     brouard  12428:       }else if (line[0] == '#') {
                   12429:        /* If line starts with a # it is a comment */
1.254     brouard  12430:        numlinepar++;
                   12431:        fputs(line,stdout);
                   12432:        fputs(line,ficparo);
                   12433:        fputs(line,ficlog);
1.299     brouard  12434:        fputs(line,ficres);
1.254     brouard  12435:        continue;
1.258     brouard  12436:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12437:        parameterline=11;
1.296     brouard  12438:       else if(sscanf(line,"prevbackcast=%[^\n]\n",modeltemp))
1.258     brouard  12439:        parameterline=12;
1.307     brouard  12440:       else if(sscanf(line,"result:%[^\n]\n",modeltemp)){
1.258     brouard  12441:        parameterline=13;
1.307     brouard  12442:       }
1.258     brouard  12443:       else{
                   12444:        parameterline=14;
1.254     brouard  12445:       }
1.308   ! brouard  12446:       switch (parameterline){ /* =0 only if only comments */
1.258     brouard  12447:       case 11:
1.296     brouard  12448:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12449:                  fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.258     brouard  12450:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12451:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12452:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12453:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12454:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12455:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
1.296     brouard  12456:           prvforecast = 1;
                   12457:        } 
                   12458:        else if((num_filled=sscanf(line,"prevforecast=%d yearsfproj=%lf mobil_average=%d\n",&prevfcast,&yrfproj,&mobilavproj)) !=EOF){/* && (num_filled == 3))*/
1.302     brouard  12459:          printf("prevforecast=%d yearsfproj=%lf.2 mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12460:          fprintf(ficlog,"prevforecast=%d yearsfproj=%lf.2 mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12461:          fprintf(ficres,"prevforecast=%d yearsfproj=%lf.2 mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
1.296     brouard  12462:           prvforecast = 2;
                   12463:        }
                   12464:        else {
                   12465:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearsfproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12466:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12467:          goto end;
1.258     brouard  12468:        }
1.254     brouard  12469:        break;
1.258     brouard  12470:       case 12:
1.296     brouard  12471:        if((num_filled=sscanf(line,"prevbackcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&prevbcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12472:           fprintf(ficparo,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12473:          printf("prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12474:          fprintf(ficlog,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12475:          fprintf(ficres,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12476:          /* day and month of back2 are not used but only year anback2.*/
1.273     brouard  12477:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12478:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.296     brouard  12479:           prvbackcast = 1;
                   12480:        } 
                   12481:        else if((num_filled=sscanf(line,"prevbackcast=%d yearsbproj=%lf mobil_average=%d\n",&prevbcast,&yrbproj,&mobilavproj)) ==3){/* && (num_filled == 3))*/
1.302     brouard  12482:          printf("prevbackcast=%d yearsbproj=%lf.2 mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12483:          fprintf(ficlog,"prevbackcast=%d yearsbproj=%lf.2 mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12484:          fprintf(ficres,"prevbackcast=%d yearsbproj=%lf.2 mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
1.296     brouard  12485:           prvbackcast = 2;
                   12486:        }
                   12487:        else {
                   12488:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearsbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12489:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12490:          goto end;
1.258     brouard  12491:        }
1.230     brouard  12492:        break;
1.258     brouard  12493:       case 13:
1.307     brouard  12494:        num_filled=sscanf(line,"result:%[^\n]\n",resultline);
                   12495:        nresult++; /* Sum of resultlines */
                   12496:        printf("Result %d: result:%s\n",nresult, resultline);
                   12497:        if(nresult > MAXRESULTLINES){
                   12498:          printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINES,nresult,rfileres);
                   12499:          fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINES,nresult,rfileres);
                   12500:          goto end;
                   12501:        }
                   12502:        decoderesult(resultline, nresult); /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
                   12503:        fprintf(ficparo,"result: %s\n",resultline);
                   12504:        fprintf(ficres,"result: %s\n",resultline);
                   12505:        fprintf(ficlog,"result: %s\n",resultline);
                   12506:        break;
                   12507:       case 14:
                   12508:        printf("Error: Unknown command '%s'\n",line);
                   12509:        fprintf(ficlog,"Error: Unknown command '%s'\n",line);
                   12510:        if(ncovmodel >=2 && nresult==0 ){
                   12511:          printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
                   12512:          fprintf(ficlog,"ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12513:        }
1.307     brouard  12514:        /* goto end; */
                   12515:        break;
1.308   ! brouard  12516:       case 15:
        !          12517:        printf("End of resultlines.\n");
        !          12518:        fprintf(ficlog,"End of resultlines.\n");
        !          12519:        break;
        !          12520:       default: /* parameterline =0 */
1.307     brouard  12521:        nresult=1;
                   12522:        decoderesult(".",nresult ); /* No covariate */
1.258     brouard  12523:       } /* End switch parameterline */
                   12524:     }while(endishere==0); /* End do */
1.126     brouard  12525:     
1.230     brouard  12526:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12527:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12528:     
                   12529:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12530:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12531:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12532: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12533: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12534:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12535: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12536: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12537:     }else{
1.270     brouard  12538:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
1.296     brouard  12539:       /* It seems that anprojd which is computed from the mean year at interview which is known yet because of freqsummary */
                   12540:       /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */ /* Done in freqsummary */
                   12541:       if(prvforecast==1){
                   12542:         dateprojd=(jproj1+12*mproj1+365*anproj1)/365;
                   12543:         jprojd=jproj1;
                   12544:         mprojd=mproj1;
                   12545:         anprojd=anproj1;
                   12546:         dateprojf=(jproj2+12*mproj2+365*anproj2)/365;
                   12547:         jprojf=jproj2;
                   12548:         mprojf=mproj2;
                   12549:         anprojf=anproj2;
                   12550:       } else if(prvforecast == 2){
                   12551:         dateprojd=dateintmean;
                   12552:         date2dmy(dateprojd,&jprojd, &mprojd, &anprojd);
                   12553:         dateprojf=dateintmean+yrfproj;
                   12554:         date2dmy(dateprojf,&jprojf, &mprojf, &anprojf);
                   12555:       }
                   12556:       if(prvbackcast==1){
                   12557:         datebackd=(jback1+12*mback1+365*anback1)/365;
                   12558:         jbackd=jback1;
                   12559:         mbackd=mback1;
                   12560:         anbackd=anback1;
                   12561:         datebackf=(jback2+12*mback2+365*anback2)/365;
                   12562:         jbackf=jback2;
                   12563:         mbackf=mback2;
                   12564:         anbackf=anback2;
                   12565:       } else if(prvbackcast == 2){
                   12566:         datebackd=dateintmean;
                   12567:         date2dmy(datebackd,&jbackd, &mbackd, &anbackd);
                   12568:         datebackf=dateintmean-yrbproj;
                   12569:         date2dmy(datebackf,&jbackf, &mbackf, &anbackf);
                   12570:       }
                   12571:       
                   12572:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, prevbcast, pathc,p, (int)anprojd-bage, (int)anbackd-fage);
1.220     brouard  12573:     }
                   12574:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.296     brouard  12575:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,prevbcast, estepm, \
                   12576:                 jprev1,mprev1,anprev1,dateprev1, dateprojd, datebackd,jprev2,mprev2,anprev2,dateprev2,dateprojf, datebackf);
1.220     brouard  12577:                
1.225     brouard  12578:     /*------------ free_vector  -------------*/
                   12579:     /*  chdir(path); */
1.220     brouard  12580:                
1.215     brouard  12581:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12582:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12583:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12584:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12585:     free_lvector(num,firstobs,lastobs);
                   12586:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12587:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12588:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12589:     fclose(ficparo);
                   12590:     fclose(ficres);
1.220     brouard  12591:                
                   12592:                
1.186     brouard  12593:     /* Other results (useful)*/
1.220     brouard  12594:                
                   12595:                
1.126     brouard  12596:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12597:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12598:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12599:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12600:     fclose(ficrespl);
                   12601: 
                   12602:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12603:     /*#include "hpijx.h"*/
                   12604:     hPijx(p, bage, fage);
1.145     brouard  12605:     fclose(ficrespij);
1.227     brouard  12606:     
1.220     brouard  12607:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12608:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12609:     k=1;
1.126     brouard  12610:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12611:     
1.269     brouard  12612:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12613:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12614:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12615:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12616:        for(k=1;k<=ncovcombmax;k++)
                   12617:          probs[i][j][k]=0.;
1.269     brouard  12618:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12619:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12620:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12621:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12622:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12623:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12624:          for(k=1;k<=ncovcombmax;k++)
                   12625:            mobaverages[i][j][k]=0.;
1.219     brouard  12626:       mobaverage=mobaverages;
                   12627:       if (mobilav!=0) {
1.235     brouard  12628:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12629:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12630:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12631:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12632:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12633:        }
1.269     brouard  12634:       } else if (mobilavproj !=0) {
1.235     brouard  12635:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12636:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12637:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12638:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12639:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12640:        }
1.269     brouard  12641:       }else{
                   12642:        printf("Internal error moving average\n");
                   12643:        fflush(stdout);
                   12644:        exit(1);
1.219     brouard  12645:       }
                   12646:     }/* end if moving average */
1.227     brouard  12647:     
1.126     brouard  12648:     /*---------- Forecasting ------------------*/
1.296     brouard  12649:     if(prevfcast==1){ 
                   12650:       /*   /\*    if(stepm ==1){*\/ */
                   12651:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12652:       /*This done previously after freqsummary.*/
                   12653:       /*   dateprojd=(jproj1+12*mproj1+365*anproj1)/365; */
                   12654:       /*   dateprojf=(jproj2+12*mproj2+365*anproj2)/365; */
                   12655:       
                   12656:       /* } else if (prvforecast==2){ */
                   12657:       /*   /\*    if(stepm ==1){*\/ */
                   12658:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12659:       /* } */
                   12660:       /*prevforecast(fileresu, dateintmean, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);*/
                   12661:       prevforecast(fileresu,dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, p, cptcoveff);
1.126     brouard  12662:     }
1.269     brouard  12663: 
1.296     brouard  12664:     /* Prevbcasting */
                   12665:     if(prevbcast==1){
1.219     brouard  12666:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12667:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12668:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12669: 
                   12670:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12671: 
                   12672:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12673: 
1.219     brouard  12674:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12675:       fclose(ficresplb);
                   12676: 
1.222     brouard  12677:       hBijx(p, bage, fage, mobaverage);
                   12678:       fclose(ficrespijb);
1.219     brouard  12679: 
1.296     brouard  12680:       /* /\* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, *\/ */
                   12681:       /* /\*                  mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); *\/ */
                   12682:       /* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, */
                   12683:       /*                      mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
                   12684:       prevbackforecast(fileresu, mobaverage, dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2,
                   12685:                       mobilavproj, bage, fage, firstpass, lastpass, p, cptcoveff);
                   12686: 
                   12687:       
1.269     brouard  12688:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12689: 
                   12690:       
1.269     brouard  12691:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12692:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12693:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12694:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.296     brouard  12695:     }    /* end  Prevbcasting */
1.268     brouard  12696:  
1.186     brouard  12697:  
                   12698:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12699: 
1.215     brouard  12700:     free_ivector(wav,1,imx);
                   12701:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12702:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12703:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12704:                
                   12705:                
1.127     brouard  12706:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12707:                
1.201     brouard  12708:     strcpy(filerese,"E_");
                   12709:     strcat(filerese,fileresu);
1.126     brouard  12710:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12711:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12712:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12713:     }
1.208     brouard  12714:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12715:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12716: 
                   12717:     pstamp(ficreseij);
1.219     brouard  12718:                
1.235     brouard  12719:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12720:     if (cptcovn < 1){i1=1;}
                   12721:     
                   12722:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12723:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12724:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12725:        continue;
1.219     brouard  12726:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12727:       printf("\n#****** ");
1.225     brouard  12728:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12729:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12730:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12731:       }
                   12732:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12733:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12734:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12735:       }
                   12736:       fprintf(ficreseij,"******\n");
1.235     brouard  12737:       printf("******\n");
1.219     brouard  12738:       
                   12739:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12740:       oldm=oldms;savm=savms;
1.235     brouard  12741:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12742:       
1.219     brouard  12743:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12744:     }
                   12745:     fclose(ficreseij);
1.208     brouard  12746:     printf("done evsij\n");fflush(stdout);
                   12747:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12748: 
1.218     brouard  12749:                
1.227     brouard  12750:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12751:                
1.201     brouard  12752:     strcpy(filerest,"T_");
                   12753:     strcat(filerest,fileresu);
1.127     brouard  12754:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12755:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12756:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12757:     }
1.208     brouard  12758:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12759:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12760:     strcpy(fileresstde,"STDE_");
                   12761:     strcat(fileresstde,fileresu);
1.126     brouard  12762:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12763:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12764:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12765:     }
1.227     brouard  12766:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12767:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12768: 
1.201     brouard  12769:     strcpy(filerescve,"CVE_");
                   12770:     strcat(filerescve,fileresu);
1.126     brouard  12771:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12772:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12773:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12774:     }
1.227     brouard  12775:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12776:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12777: 
1.201     brouard  12778:     strcpy(fileresv,"V_");
                   12779:     strcat(fileresv,fileresu);
1.126     brouard  12780:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12781:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12782:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12783:     }
1.227     brouard  12784:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12785:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12786: 
1.235     brouard  12787:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12788:     if (cptcovn < 1){i1=1;}
                   12789:     
                   12790:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12791:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12792:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12793:        continue;
1.242     brouard  12794:       printf("\n#****** Result for:");
                   12795:       fprintf(ficrest,"\n#****** Result for:");
                   12796:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12797:       for(j=1;j<=cptcoveff;j++){ 
                   12798:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12799:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12800:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12801:       }
1.235     brouard  12802:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12803:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12804:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12805:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12806:       }        
1.208     brouard  12807:       fprintf(ficrest,"******\n");
1.227     brouard  12808:       fprintf(ficlog,"******\n");
                   12809:       printf("******\n");
1.208     brouard  12810:       
                   12811:       fprintf(ficresstdeij,"\n#****** ");
                   12812:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12813:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12814:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12815:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12816:       }
1.235     brouard  12817:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12818:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12819:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12820:       }        
1.208     brouard  12821:       fprintf(ficresstdeij,"******\n");
                   12822:       fprintf(ficrescveij,"******\n");
                   12823:       
                   12824:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12825:       /* pstamp(ficresvij); */
1.225     brouard  12826:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12827:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12828:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12829:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12830:       }        
1.208     brouard  12831:       fprintf(ficresvij,"******\n");
                   12832:       
                   12833:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12834:       oldm=oldms;savm=savms;
1.235     brouard  12835:       printf(" cvevsij ");
                   12836:       fprintf(ficlog, " cvevsij ");
                   12837:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12838:       printf(" end cvevsij \n ");
                   12839:       fprintf(ficlog, " end cvevsij \n ");
                   12840:       
                   12841:       /*
                   12842:        */
                   12843:       /* goto endfree; */
                   12844:       
                   12845:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12846:       pstamp(ficrest);
                   12847:       
1.269     brouard  12848:       epj=vector(1,nlstate+1);
1.208     brouard  12849:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12850:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12851:        cptcod= 0; /* To be deleted */
                   12852:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12853:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12854:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12855:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12856:        if(vpopbased==1)
                   12857:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12858:        else
1.288     brouard  12859:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12860:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12861:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12862:        fprintf(ficrest,"\n");
                   12863:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  12864:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   12865:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12866:        for(age=bage; age <=fage ;age++){
1.235     brouard  12867:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12868:          if (vpopbased==1) {
                   12869:            if(mobilav ==0){
                   12870:              for(i=1; i<=nlstate;i++)
                   12871:                prlim[i][i]=probs[(int)age][i][k];
                   12872:            }else{ /* mobilav */ 
                   12873:              for(i=1; i<=nlstate;i++)
                   12874:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12875:            }
                   12876:          }
1.219     brouard  12877:          
1.227     brouard  12878:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12879:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12880:          /* printf(" age %4.0f ",age); */
                   12881:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12882:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12883:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12884:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12885:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12886:            }
                   12887:            epj[nlstate+1] +=epj[j];
                   12888:          }
                   12889:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12890:          
1.227     brouard  12891:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12892:            for(j=1;j <=nlstate;j++)
                   12893:              vepp += vareij[i][j][(int)age];
                   12894:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12895:          for(j=1;j <=nlstate;j++){
                   12896:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12897:          }
                   12898:          fprintf(ficrest,"\n");
                   12899:        }
1.208     brouard  12900:       } /* End vpopbased */
1.269     brouard  12901:       free_vector(epj,1,nlstate+1);
1.208     brouard  12902:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12903:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12904:       printf("done selection\n");fflush(stdout);
                   12905:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12906:       
1.235     brouard  12907:     } /* End k selection */
1.227     brouard  12908: 
                   12909:     printf("done State-specific expectancies\n");fflush(stdout);
                   12910:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12911: 
1.288     brouard  12912:     /* variance-covariance of forward period prevalence*/
1.269     brouard  12913:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12914: 
1.227     brouard  12915:     
1.290     brouard  12916:     free_vector(weight,firstobs,lastobs);
1.227     brouard  12917:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  12918:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   12919:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   12920:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   12921:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  12922:     free_ivector(tab,1,NCOVMAX);
                   12923:     fclose(ficresstdeij);
                   12924:     fclose(ficrescveij);
                   12925:     fclose(ficresvij);
                   12926:     fclose(ficrest);
                   12927:     fclose(ficpar);
                   12928:     
                   12929:     
1.126     brouard  12930:     /*---------- End : free ----------------*/
1.219     brouard  12931:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12932:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12933:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12934:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12935:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12936:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12937:   /* endfree:*/
                   12938:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12939:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12940:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  12941:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   12942:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   12943:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   12944:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  12945:   free_matrix(matcov,1,npar,1,npar);
                   12946:   free_matrix(hess,1,npar,1,npar);
                   12947:   /*free_vector(delti,1,npar);*/
                   12948:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12949:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12950:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12951:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12952:   
                   12953:   free_ivector(ncodemax,1,NCOVMAX);
                   12954:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   12955:   free_ivector(Dummy,-1,NCOVMAX);
                   12956:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  12957:   free_ivector(DummyV,1,NCOVMAX);
                   12958:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  12959:   free_ivector(Typevar,-1,NCOVMAX);
                   12960:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  12961:   free_ivector(TvarsQ,1,NCOVMAX);
                   12962:   free_ivector(TvarsQind,1,NCOVMAX);
                   12963:   free_ivector(TvarsD,1,NCOVMAX);
                   12964:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  12965:   free_ivector(TvarFD,1,NCOVMAX);
                   12966:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  12967:   free_ivector(TvarF,1,NCOVMAX);
                   12968:   free_ivector(TvarFind,1,NCOVMAX);
                   12969:   free_ivector(TvarV,1,NCOVMAX);
                   12970:   free_ivector(TvarVind,1,NCOVMAX);
                   12971:   free_ivector(TvarA,1,NCOVMAX);
                   12972:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  12973:   free_ivector(TvarFQ,1,NCOVMAX);
                   12974:   free_ivector(TvarFQind,1,NCOVMAX);
                   12975:   free_ivector(TvarVD,1,NCOVMAX);
                   12976:   free_ivector(TvarVDind,1,NCOVMAX);
                   12977:   free_ivector(TvarVQ,1,NCOVMAX);
                   12978:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  12979:   free_ivector(Tvarsel,1,NCOVMAX);
                   12980:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  12981:   free_ivector(Tposprod,1,NCOVMAX);
                   12982:   free_ivector(Tprod,1,NCOVMAX);
                   12983:   free_ivector(Tvaraff,1,NCOVMAX);
                   12984:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   12985:   free_ivector(Tage,1,NCOVMAX);
                   12986:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  12987:   free_ivector(TmodelInvind,1,NCOVMAX);
                   12988:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  12989:   
                   12990:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   12991:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  12992:   fflush(fichtm);
                   12993:   fflush(ficgp);
                   12994:   
1.227     brouard  12995:   
1.126     brouard  12996:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  12997:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   12998:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  12999:   }else{
                   13000:     printf("End of Imach\n");
                   13001:     fprintf(ficlog,"End of Imach\n");
                   13002:   }
                   13003:   printf("See log file on %s\n",filelog);
                   13004:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  13005:   /*(void) gettimeofday(&end_time,&tzp);*/
                   13006:   rend_time = time(NULL);  
                   13007:   end_time = *localtime(&rend_time);
                   13008:   /* tml = *localtime(&end_time.tm_sec); */
                   13009:   strcpy(strtend,asctime(&end_time));
1.126     brouard  13010:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   13011:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  13012:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  13013:   
1.157     brouard  13014:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   13015:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   13016:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  13017:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   13018: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   13019:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13020:   fclose(fichtm);
                   13021:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13022:   fclose(fichtmcov);
                   13023:   fclose(ficgp);
                   13024:   fclose(ficlog);
                   13025:   /*------ End -----------*/
1.227     brouard  13026:   
1.281     brouard  13027: 
                   13028: /* Executes gnuplot */
1.227     brouard  13029:   
                   13030:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  13031: #ifdef WIN32
1.227     brouard  13032:   if (_chdir(pathcd) != 0)
                   13033:     printf("Can't move to directory %s!\n",path);
                   13034:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  13035: #else
1.227     brouard  13036:     if(chdir(pathcd) != 0)
                   13037:       printf("Can't move to directory %s!\n", path);
                   13038:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  13039: #endif 
1.126     brouard  13040:     printf("Current directory %s!\n",pathcd);
                   13041:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   13042:   sprintf(plotcmd,"gnuplot");
1.157     brouard  13043: #ifdef _WIN32
1.126     brouard  13044:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   13045: #endif
                   13046:   if(!stat(plotcmd,&info)){
1.158     brouard  13047:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13048:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  13049:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  13050:     }else
                   13051:       strcpy(pplotcmd,plotcmd);
1.157     brouard  13052: #ifdef __unix
1.126     brouard  13053:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   13054:     if(!stat(plotcmd,&info)){
1.158     brouard  13055:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13056:     }else
                   13057:       strcpy(pplotcmd,plotcmd);
                   13058: #endif
                   13059:   }else
                   13060:     strcpy(pplotcmd,plotcmd);
                   13061:   
                   13062:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  13063:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292     brouard  13064:   strcpy(pplotcmd,plotcmd);
1.227     brouard  13065:   
1.126     brouard  13066:   if((outcmd=system(plotcmd)) != 0){
1.292     brouard  13067:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  13068:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  13069:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292     brouard  13070:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  13071:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292     brouard  13072:       strcpy(plotcmd,pplotcmd);
                   13073:     }
1.126     brouard  13074:   }
1.158     brouard  13075:   printf(" Successful, please wait...");
1.126     brouard  13076:   while (z[0] != 'q') {
                   13077:     /* chdir(path); */
1.154     brouard  13078:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  13079:     scanf("%s",z);
                   13080: /*     if (z[0] == 'c') system("./imach"); */
                   13081:     if (z[0] == 'e') {
1.158     brouard  13082: #ifdef __APPLE__
1.152     brouard  13083:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  13084: #elif __linux
                   13085:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  13086: #else
1.152     brouard  13087:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  13088: #endif
                   13089:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   13090:       system(pplotcmd);
1.126     brouard  13091:     }
                   13092:     else if (z[0] == 'g') system(plotcmd);
                   13093:     else if (z[0] == 'q') exit(0);
                   13094:   }
1.227     brouard  13095: end:
1.126     brouard  13096:   while (z[0] != 'q') {
1.195     brouard  13097:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  13098:     scanf("%s",z);
                   13099:   }
1.283     brouard  13100:   printf("End\n");
1.282     brouard  13101:   exit(0);
1.126     brouard  13102: }

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