Annotation of imach/src/imach.c, revision 1.311

1.311   ! brouard     1: /* $Id: imach.c,v 1.310 2022/03/17 08:45:53 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.311   ! brouard     4:   Revision 1.310  2022/03/17 08:45:53  brouard
        !             5:   Summary: 99r25
        !             6: 
        !             7:   Improving detection of errors: result lines should be compatible with
        !             8:   the model.
        !             9: 
1.310     brouard    10:   Revision 1.309  2021/05/20 12:39:14  brouard
                     11:   Summary: Version 0.99r24
                     12: 
1.309     brouard    13:   Revision 1.308  2021/03/31 13:11:57  brouard
                     14:   Summary: Version 0.99r23
                     15: 
                     16: 
                     17:   * imach.c (Module): Still bugs in the result loop. Thank to Holly Benett
                     18: 
1.308     brouard    19:   Revision 1.307  2021/03/08 18:11:32  brouard
                     20:   Summary: 0.99r22 fixed bug on result:
                     21: 
1.307     brouard    22:   Revision 1.306  2021/02/20 15:44:02  brouard
                     23:   Summary: Version 0.99r21
                     24: 
                     25:   * imach.c (Module): Fix bug on quitting after result lines!
                     26:   (Module): Version 0.99r21
                     27: 
1.306     brouard    28:   Revision 1.305  2021/02/20 15:28:30  brouard
                     29:   * imach.c (Module): Fix bug on quitting after result lines!
                     30: 
1.305     brouard    31:   Revision 1.304  2021/02/12 11:34:20  brouard
                     32:   * imach.c (Module): The use of a Windows BOM (huge) file is now an error
                     33: 
1.304     brouard    34:   Revision 1.303  2021/02/11 19:50:15  brouard
                     35:   *  (Module): imach.c Someone entered 'results:' instead of 'result:'. Now it is an error which is printed.
                     36: 
1.303     brouard    37:   Revision 1.302  2020/02/22 21:00:05  brouard
                     38:   *  (Module): imach.c Update mle=-3 (for computing Life expectancy
                     39:   and life table from the data without any state)
                     40: 
1.302     brouard    41:   Revision 1.301  2019/06/04 13:51:20  brouard
                     42:   Summary: Error in 'r'parameter file backcast yearsbproj instead of yearsfproj
                     43: 
1.301     brouard    44:   Revision 1.300  2019/05/22 19:09:45  brouard
                     45:   Summary: version 0.99r19 of May 2019
                     46: 
1.300     brouard    47:   Revision 1.299  2019/05/22 18:37:08  brouard
                     48:   Summary: Cleaned 0.99r19
                     49: 
1.299     brouard    50:   Revision 1.298  2019/05/22 18:19:56  brouard
                     51:   *** empty log message ***
                     52: 
1.298     brouard    53:   Revision 1.297  2019/05/22 17:56:10  brouard
                     54:   Summary: Fix bug by moving date2dmy and nhstepm which gaefin=-1
                     55: 
1.297     brouard    56:   Revision 1.296  2019/05/20 13:03:18  brouard
                     57:   Summary: Projection syntax simplified
                     58: 
                     59: 
                     60:   We can now start projections, forward or backward, from the mean date
                     61:   of inteviews up to or down to a number of years of projection:
                     62:   prevforecast=1 yearsfproj=15.3 mobil_average=0
                     63:   or
                     64:   prevforecast=1 starting-proj-date=1/1/2007 final-proj-date=12/31/2017 mobil_average=0
                     65:   or
                     66:   prevbackcast=1 yearsbproj=12.3 mobil_average=1
                     67:   or
                     68:   prevbackcast=1 starting-back-date=1/10/1999 final-back-date=1/1/1985 mobil_average=1
                     69: 
1.296     brouard    70:   Revision 1.295  2019/05/18 09:52:50  brouard
                     71:   Summary: doxygen tex bug
                     72: 
1.295     brouard    73:   Revision 1.294  2019/05/16 14:54:33  brouard
                     74:   Summary: There was some wrong lines added
                     75: 
1.294     brouard    76:   Revision 1.293  2019/05/09 15:17:34  brouard
                     77:   *** empty log message ***
                     78: 
1.293     brouard    79:   Revision 1.292  2019/05/09 14:17:20  brouard
                     80:   Summary: Some updates
                     81: 
1.292     brouard    82:   Revision 1.291  2019/05/09 13:44:18  brouard
                     83:   Summary: Before ncovmax
                     84: 
1.291     brouard    85:   Revision 1.290  2019/05/09 13:39:37  brouard
                     86:   Summary: 0.99r18 unlimited number of individuals
                     87: 
                     88:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                     89: 
1.290     brouard    90:   Revision 1.289  2018/12/13 09:16:26  brouard
                     91:   Summary: Bug for young ages (<-30) will be in r17
                     92: 
1.289     brouard    93:   Revision 1.288  2018/05/02 20:58:27  brouard
                     94:   Summary: Some bugs fixed
                     95: 
1.288     brouard    96:   Revision 1.287  2018/05/01 17:57:25  brouard
                     97:   Summary: Bug fixed by providing frequencies only for non missing covariates
                     98: 
1.287     brouard    99:   Revision 1.286  2018/04/27 14:27:04  brouard
                    100:   Summary: some minor bugs
                    101: 
1.286     brouard   102:   Revision 1.285  2018/04/21 21:02:16  brouard
                    103:   Summary: Some bugs fixed, valgrind tested
                    104: 
1.285     brouard   105:   Revision 1.284  2018/04/20 05:22:13  brouard
                    106:   Summary: Computing mean and stdeviation of fixed quantitative variables
                    107: 
1.284     brouard   108:   Revision 1.283  2018/04/19 14:49:16  brouard
                    109:   Summary: Some minor bugs fixed
                    110: 
1.283     brouard   111:   Revision 1.282  2018/02/27 22:50:02  brouard
                    112:   *** empty log message ***
                    113: 
1.282     brouard   114:   Revision 1.281  2018/02/27 19:25:23  brouard
                    115:   Summary: Adding second argument for quitting
                    116: 
1.281     brouard   117:   Revision 1.280  2018/02/21 07:58:13  brouard
                    118:   Summary: 0.99r15
                    119: 
                    120:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                    121: 
1.280     brouard   122:   Revision 1.279  2017/07/20 13:35:01  brouard
                    123:   Summary: temporary working
                    124: 
1.279     brouard   125:   Revision 1.278  2017/07/19 14:09:02  brouard
                    126:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                    127: 
1.278     brouard   128:   Revision 1.277  2017/07/17 08:53:49  brouard
                    129:   Summary: BOM files can be read now
                    130: 
1.277     brouard   131:   Revision 1.276  2017/06/30 15:48:31  brouard
                    132:   Summary: Graphs improvements
                    133: 
1.276     brouard   134:   Revision 1.275  2017/06/30 13:39:33  brouard
                    135:   Summary: Saito's color
                    136: 
1.275     brouard   137:   Revision 1.274  2017/06/29 09:47:08  brouard
                    138:   Summary: Version 0.99r14
                    139: 
1.274     brouard   140:   Revision 1.273  2017/06/27 11:06:02  brouard
                    141:   Summary: More documentation on projections
                    142: 
1.273     brouard   143:   Revision 1.272  2017/06/27 10:22:40  brouard
                    144:   Summary: Color of backprojection changed from 6 to 5(yellow)
                    145: 
1.272     brouard   146:   Revision 1.271  2017/06/27 10:17:50  brouard
                    147:   Summary: Some bug with rint
                    148: 
1.271     brouard   149:   Revision 1.270  2017/05/24 05:45:29  brouard
                    150:   *** empty log message ***
                    151: 
1.270     brouard   152:   Revision 1.269  2017/05/23 08:39:25  brouard
                    153:   Summary: Code into subroutine, cleanings
                    154: 
1.269     brouard   155:   Revision 1.268  2017/05/18 20:09:32  brouard
                    156:   Summary: backprojection and confidence intervals of backprevalence
                    157: 
1.268     brouard   158:   Revision 1.267  2017/05/13 10:25:05  brouard
                    159:   Summary: temporary save for backprojection
                    160: 
1.267     brouard   161:   Revision 1.266  2017/05/13 07:26:12  brouard
                    162:   Summary: Version 0.99r13 (improvements and bugs fixed)
                    163: 
1.266     brouard   164:   Revision 1.265  2017/04/26 16:22:11  brouard
                    165:   Summary: imach 0.99r13 Some bugs fixed
                    166: 
1.265     brouard   167:   Revision 1.264  2017/04/26 06:01:29  brouard
                    168:   Summary: Labels in graphs
                    169: 
1.264     brouard   170:   Revision 1.263  2017/04/24 15:23:15  brouard
                    171:   Summary: to save
                    172: 
1.263     brouard   173:   Revision 1.262  2017/04/18 16:48:12  brouard
                    174:   *** empty log message ***
                    175: 
1.262     brouard   176:   Revision 1.261  2017/04/05 10:14:09  brouard
                    177:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    178: 
1.261     brouard   179:   Revision 1.260  2017/04/04 17:46:59  brouard
                    180:   Summary: Gnuplot indexations fixed (humm)
                    181: 
1.260     brouard   182:   Revision 1.259  2017/04/04 13:01:16  brouard
                    183:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    184: 
1.259     brouard   185:   Revision 1.258  2017/04/03 10:17:47  brouard
                    186:   Summary: Version 0.99r12
                    187: 
                    188:   Some cleanings, conformed with updated documentation.
                    189: 
1.258     brouard   190:   Revision 1.257  2017/03/29 16:53:30  brouard
                    191:   Summary: Temp
                    192: 
1.257     brouard   193:   Revision 1.256  2017/03/27 05:50:23  brouard
                    194:   Summary: Temporary
                    195: 
1.256     brouard   196:   Revision 1.255  2017/03/08 16:02:28  brouard
                    197:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    198: 
1.255     brouard   199:   Revision 1.254  2017/03/08 07:13:00  brouard
                    200:   Summary: Fixing data parameter line
                    201: 
1.254     brouard   202:   Revision 1.253  2016/12/15 11:59:41  brouard
                    203:   Summary: 0.99 in progress
                    204: 
1.253     brouard   205:   Revision 1.252  2016/09/15 21:15:37  brouard
                    206:   *** empty log message ***
                    207: 
1.252     brouard   208:   Revision 1.251  2016/09/15 15:01:13  brouard
                    209:   Summary: not working
                    210: 
1.251     brouard   211:   Revision 1.250  2016/09/08 16:07:27  brouard
                    212:   Summary: continue
                    213: 
1.250     brouard   214:   Revision 1.249  2016/09/07 17:14:18  brouard
                    215:   Summary: Starting values from frequencies
                    216: 
1.249     brouard   217:   Revision 1.248  2016/09/07 14:10:18  brouard
                    218:   *** empty log message ***
                    219: 
1.248     brouard   220:   Revision 1.247  2016/09/02 11:11:21  brouard
                    221:   *** empty log message ***
                    222: 
1.247     brouard   223:   Revision 1.246  2016/09/02 08:49:22  brouard
                    224:   *** empty log message ***
                    225: 
1.246     brouard   226:   Revision 1.245  2016/09/02 07:25:01  brouard
                    227:   *** empty log message ***
                    228: 
1.245     brouard   229:   Revision 1.244  2016/09/02 07:17:34  brouard
                    230:   *** empty log message ***
                    231: 
1.244     brouard   232:   Revision 1.243  2016/09/02 06:45:35  brouard
                    233:   *** empty log message ***
                    234: 
1.243     brouard   235:   Revision 1.242  2016/08/30 15:01:20  brouard
                    236:   Summary: Fixing a lots
                    237: 
1.242     brouard   238:   Revision 1.241  2016/08/29 17:17:25  brouard
                    239:   Summary: gnuplot problem in Back projection to fix
                    240: 
1.241     brouard   241:   Revision 1.240  2016/08/29 07:53:18  brouard
                    242:   Summary: Better
                    243: 
1.240     brouard   244:   Revision 1.239  2016/08/26 15:51:03  brouard
                    245:   Summary: Improvement in Powell output in order to copy and paste
                    246: 
                    247:   Author:
                    248: 
1.239     brouard   249:   Revision 1.238  2016/08/26 14:23:35  brouard
                    250:   Summary: Starting tests of 0.99
                    251: 
1.238     brouard   252:   Revision 1.237  2016/08/26 09:20:19  brouard
                    253:   Summary: to valgrind
                    254: 
1.237     brouard   255:   Revision 1.236  2016/08/25 10:50:18  brouard
                    256:   *** empty log message ***
                    257: 
1.236     brouard   258:   Revision 1.235  2016/08/25 06:59:23  brouard
                    259:   *** empty log message ***
                    260: 
1.235     brouard   261:   Revision 1.234  2016/08/23 16:51:20  brouard
                    262:   *** empty log message ***
                    263: 
1.234     brouard   264:   Revision 1.233  2016/08/23 07:40:50  brouard
                    265:   Summary: not working
                    266: 
1.233     brouard   267:   Revision 1.232  2016/08/22 14:20:21  brouard
                    268:   Summary: not working
                    269: 
1.232     brouard   270:   Revision 1.231  2016/08/22 07:17:15  brouard
                    271:   Summary: not working
                    272: 
1.231     brouard   273:   Revision 1.230  2016/08/22 06:55:53  brouard
                    274:   Summary: Not working
                    275: 
1.230     brouard   276:   Revision 1.229  2016/07/23 09:45:53  brouard
                    277:   Summary: Completing for func too
                    278: 
1.229     brouard   279:   Revision 1.228  2016/07/22 17:45:30  brouard
                    280:   Summary: Fixing some arrays, still debugging
                    281: 
1.227     brouard   282:   Revision 1.226  2016/07/12 18:42:34  brouard
                    283:   Summary: temp
                    284: 
1.226     brouard   285:   Revision 1.225  2016/07/12 08:40:03  brouard
                    286:   Summary: saving but not running
                    287: 
1.225     brouard   288:   Revision 1.224  2016/07/01 13:16:01  brouard
                    289:   Summary: Fixes
                    290: 
1.224     brouard   291:   Revision 1.223  2016/02/19 09:23:35  brouard
                    292:   Summary: temporary
                    293: 
1.223     brouard   294:   Revision 1.222  2016/02/17 08:14:50  brouard
                    295:   Summary: Probably last 0.98 stable version 0.98r6
                    296: 
1.222     brouard   297:   Revision 1.221  2016/02/15 23:35:36  brouard
                    298:   Summary: minor bug
                    299: 
1.220     brouard   300:   Revision 1.219  2016/02/15 00:48:12  brouard
                    301:   *** empty log message ***
                    302: 
1.219     brouard   303:   Revision 1.218  2016/02/12 11:29:23  brouard
                    304:   Summary: 0.99 Back projections
                    305: 
1.218     brouard   306:   Revision 1.217  2015/12/23 17:18:31  brouard
                    307:   Summary: Experimental backcast
                    308: 
1.217     brouard   309:   Revision 1.216  2015/12/18 17:32:11  brouard
                    310:   Summary: 0.98r4 Warning and status=-2
                    311: 
                    312:   Version 0.98r4 is now:
                    313:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    314:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    315:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    316: 
1.216     brouard   317:   Revision 1.215  2015/12/16 08:52:24  brouard
                    318:   Summary: 0.98r4 working
                    319: 
1.215     brouard   320:   Revision 1.214  2015/12/16 06:57:54  brouard
                    321:   Summary: temporary not working
                    322: 
1.214     brouard   323:   Revision 1.213  2015/12/11 18:22:17  brouard
                    324:   Summary: 0.98r4
                    325: 
1.213     brouard   326:   Revision 1.212  2015/11/21 12:47:24  brouard
                    327:   Summary: minor typo
                    328: 
1.212     brouard   329:   Revision 1.211  2015/11/21 12:41:11  brouard
                    330:   Summary: 0.98r3 with some graph of projected cross-sectional
                    331: 
                    332:   Author: Nicolas Brouard
                    333: 
1.211     brouard   334:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   335:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   336:   Summary: Adding ftolpl parameter
                    337:   Author: N Brouard
                    338: 
                    339:   We had difficulties to get smoothed confidence intervals. It was due
                    340:   to the period prevalence which wasn't computed accurately. The inner
                    341:   parameter ftolpl is now an outer parameter of the .imach parameter
                    342:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    343:   computation are long.
                    344: 
1.209     brouard   345:   Revision 1.208  2015/11/17 14:31:57  brouard
                    346:   Summary: temporary
                    347: 
1.208     brouard   348:   Revision 1.207  2015/10/27 17:36:57  brouard
                    349:   *** empty log message ***
                    350: 
1.207     brouard   351:   Revision 1.206  2015/10/24 07:14:11  brouard
                    352:   *** empty log message ***
                    353: 
1.206     brouard   354:   Revision 1.205  2015/10/23 15:50:53  brouard
                    355:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    356: 
1.205     brouard   357:   Revision 1.204  2015/10/01 16:20:26  brouard
                    358:   Summary: Some new graphs of contribution to likelihood
                    359: 
1.204     brouard   360:   Revision 1.203  2015/09/30 17:45:14  brouard
                    361:   Summary: looking at better estimation of the hessian
                    362: 
                    363:   Also a better criteria for convergence to the period prevalence And
                    364:   therefore adding the number of years needed to converge. (The
                    365:   prevalence in any alive state shold sum to one
                    366: 
1.203     brouard   367:   Revision 1.202  2015/09/22 19:45:16  brouard
                    368:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    369: 
1.202     brouard   370:   Revision 1.201  2015/09/15 17:34:58  brouard
                    371:   Summary: 0.98r0
                    372: 
                    373:   - Some new graphs like suvival functions
                    374:   - Some bugs fixed like model=1+age+V2.
                    375: 
1.201     brouard   376:   Revision 1.200  2015/09/09 16:53:55  brouard
                    377:   Summary: Big bug thanks to Flavia
                    378: 
                    379:   Even model=1+age+V2. did not work anymore
                    380: 
1.200     brouard   381:   Revision 1.199  2015/09/07 14:09:23  brouard
                    382:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    383: 
1.199     brouard   384:   Revision 1.198  2015/09/03 07:14:39  brouard
                    385:   Summary: 0.98q5 Flavia
                    386: 
1.198     brouard   387:   Revision 1.197  2015/09/01 18:24:39  brouard
                    388:   *** empty log message ***
                    389: 
1.197     brouard   390:   Revision 1.196  2015/08/18 23:17:52  brouard
                    391:   Summary: 0.98q5
                    392: 
1.196     brouard   393:   Revision 1.195  2015/08/18 16:28:39  brouard
                    394:   Summary: Adding a hack for testing purpose
                    395: 
                    396:   After reading the title, ftol and model lines, if the comment line has
                    397:   a q, starting with #q, the answer at the end of the run is quit. It
                    398:   permits to run test files in batch with ctest. The former workaround was
                    399:   $ echo q | imach foo.imach
                    400: 
1.195     brouard   401:   Revision 1.194  2015/08/18 13:32:00  brouard
                    402:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    403: 
1.194     brouard   404:   Revision 1.193  2015/08/04 07:17:42  brouard
                    405:   Summary: 0.98q4
                    406: 
1.193     brouard   407:   Revision 1.192  2015/07/16 16:49:02  brouard
                    408:   Summary: Fixing some outputs
                    409: 
1.192     brouard   410:   Revision 1.191  2015/07/14 10:00:33  brouard
                    411:   Summary: Some fixes
                    412: 
1.191     brouard   413:   Revision 1.190  2015/05/05 08:51:13  brouard
                    414:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    415: 
                    416:   Fix 1+age+.
                    417: 
1.190     brouard   418:   Revision 1.189  2015/04/30 14:45:16  brouard
                    419:   Summary: 0.98q2
                    420: 
1.189     brouard   421:   Revision 1.188  2015/04/30 08:27:53  brouard
                    422:   *** empty log message ***
                    423: 
1.188     brouard   424:   Revision 1.187  2015/04/29 09:11:15  brouard
                    425:   *** empty log message ***
                    426: 
1.187     brouard   427:   Revision 1.186  2015/04/23 12:01:52  brouard
                    428:   Summary: V1*age is working now, version 0.98q1
                    429: 
                    430:   Some codes had been disabled in order to simplify and Vn*age was
                    431:   working in the optimization phase, ie, giving correct MLE parameters,
                    432:   but, as usual, outputs were not correct and program core dumped.
                    433: 
1.186     brouard   434:   Revision 1.185  2015/03/11 13:26:42  brouard
                    435:   Summary: Inclusion of compile and links command line for Intel Compiler
                    436: 
1.185     brouard   437:   Revision 1.184  2015/03/11 11:52:39  brouard
                    438:   Summary: Back from Windows 8. Intel Compiler
                    439: 
1.184     brouard   440:   Revision 1.183  2015/03/10 20:34:32  brouard
                    441:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    442: 
                    443:   We use directest instead of original Powell test; probably no
                    444:   incidence on the results, but better justifications;
                    445:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    446:   wrong results.
                    447: 
1.183     brouard   448:   Revision 1.182  2015/02/12 08:19:57  brouard
                    449:   Summary: Trying to keep directest which seems simpler and more general
                    450:   Author: Nicolas Brouard
                    451: 
1.182     brouard   452:   Revision 1.181  2015/02/11 23:22:24  brouard
                    453:   Summary: Comments on Powell added
                    454: 
                    455:   Author:
                    456: 
1.181     brouard   457:   Revision 1.180  2015/02/11 17:33:45  brouard
                    458:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    459: 
1.180     brouard   460:   Revision 1.179  2015/01/04 09:57:06  brouard
                    461:   Summary: back to OS/X
                    462: 
1.179     brouard   463:   Revision 1.178  2015/01/04 09:35:48  brouard
                    464:   *** empty log message ***
                    465: 
1.178     brouard   466:   Revision 1.177  2015/01/03 18:40:56  brouard
                    467:   Summary: Still testing ilc32 on OSX
                    468: 
1.177     brouard   469:   Revision 1.176  2015/01/03 16:45:04  brouard
                    470:   *** empty log message ***
                    471: 
1.176     brouard   472:   Revision 1.175  2015/01/03 16:33:42  brouard
                    473:   *** empty log message ***
                    474: 
1.175     brouard   475:   Revision 1.174  2015/01/03 16:15:49  brouard
                    476:   Summary: Still in cross-compilation
                    477: 
1.174     brouard   478:   Revision 1.173  2015/01/03 12:06:26  brouard
                    479:   Summary: trying to detect cross-compilation
                    480: 
1.173     brouard   481:   Revision 1.172  2014/12/27 12:07:47  brouard
                    482:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    483: 
1.172     brouard   484:   Revision 1.171  2014/12/23 13:26:59  brouard
                    485:   Summary: Back from Visual C
                    486: 
                    487:   Still problem with utsname.h on Windows
                    488: 
1.171     brouard   489:   Revision 1.170  2014/12/23 11:17:12  brouard
                    490:   Summary: Cleaning some \%% back to %%
                    491: 
                    492:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    493: 
1.170     brouard   494:   Revision 1.169  2014/12/22 23:08:31  brouard
                    495:   Summary: 0.98p
                    496: 
                    497:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    498: 
1.169     brouard   499:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   500:   Summary: update
1.169     brouard   501: 
1.168     brouard   502:   Revision 1.167  2014/12/22 13:50:56  brouard
                    503:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    504: 
                    505:   Testing on Linux 64
                    506: 
1.167     brouard   507:   Revision 1.166  2014/12/22 11:40:47  brouard
                    508:   *** empty log message ***
                    509: 
1.166     brouard   510:   Revision 1.165  2014/12/16 11:20:36  brouard
                    511:   Summary: After compiling on Visual C
                    512: 
                    513:   * imach.c (Module): Merging 1.61 to 1.162
                    514: 
1.165     brouard   515:   Revision 1.164  2014/12/16 10:52:11  brouard
                    516:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    517: 
                    518:   * imach.c (Module): Merging 1.61 to 1.162
                    519: 
1.164     brouard   520:   Revision 1.163  2014/12/16 10:30:11  brouard
                    521:   * imach.c (Module): Merging 1.61 to 1.162
                    522: 
1.163     brouard   523:   Revision 1.162  2014/09/25 11:43:39  brouard
                    524:   Summary: temporary backup 0.99!
                    525: 
1.162     brouard   526:   Revision 1.1  2014/09/16 11:06:58  brouard
                    527:   Summary: With some code (wrong) for nlopt
                    528: 
                    529:   Author:
                    530: 
                    531:   Revision 1.161  2014/09/15 20:41:41  brouard
                    532:   Summary: Problem with macro SQR on Intel compiler
                    533: 
1.161     brouard   534:   Revision 1.160  2014/09/02 09:24:05  brouard
                    535:   *** empty log message ***
                    536: 
1.160     brouard   537:   Revision 1.159  2014/09/01 10:34:10  brouard
                    538:   Summary: WIN32
                    539:   Author: Brouard
                    540: 
1.159     brouard   541:   Revision 1.158  2014/08/27 17:11:51  brouard
                    542:   *** empty log message ***
                    543: 
1.158     brouard   544:   Revision 1.157  2014/08/27 16:26:55  brouard
                    545:   Summary: Preparing windows Visual studio version
                    546:   Author: Brouard
                    547: 
                    548:   In order to compile on Visual studio, time.h is now correct and time_t
                    549:   and tm struct should be used. difftime should be used but sometimes I
                    550:   just make the differences in raw time format (time(&now).
                    551:   Trying to suppress #ifdef LINUX
                    552:   Add xdg-open for __linux in order to open default browser.
                    553: 
1.157     brouard   554:   Revision 1.156  2014/08/25 20:10:10  brouard
                    555:   *** empty log message ***
                    556: 
1.156     brouard   557:   Revision 1.155  2014/08/25 18:32:34  brouard
                    558:   Summary: New compile, minor changes
                    559:   Author: Brouard
                    560: 
1.155     brouard   561:   Revision 1.154  2014/06/20 17:32:08  brouard
                    562:   Summary: Outputs now all graphs of convergence to period prevalence
                    563: 
1.154     brouard   564:   Revision 1.153  2014/06/20 16:45:46  brouard
                    565:   Summary: If 3 live state, convergence to period prevalence on same graph
                    566:   Author: Brouard
                    567: 
1.153     brouard   568:   Revision 1.152  2014/06/18 17:54:09  brouard
                    569:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    570: 
1.152     brouard   571:   Revision 1.151  2014/06/18 16:43:30  brouard
                    572:   *** empty log message ***
                    573: 
1.151     brouard   574:   Revision 1.150  2014/06/18 16:42:35  brouard
                    575:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    576:   Author: brouard
                    577: 
1.150     brouard   578:   Revision 1.149  2014/06/18 15:51:14  brouard
                    579:   Summary: Some fixes in parameter files errors
                    580:   Author: Nicolas Brouard
                    581: 
1.149     brouard   582:   Revision 1.148  2014/06/17 17:38:48  brouard
                    583:   Summary: Nothing new
                    584:   Author: Brouard
                    585: 
                    586:   Just a new packaging for OS/X version 0.98nS
                    587: 
1.148     brouard   588:   Revision 1.147  2014/06/16 10:33:11  brouard
                    589:   *** empty log message ***
                    590: 
1.147     brouard   591:   Revision 1.146  2014/06/16 10:20:28  brouard
                    592:   Summary: Merge
                    593:   Author: Brouard
                    594: 
                    595:   Merge, before building revised version.
                    596: 
1.146     brouard   597:   Revision 1.145  2014/06/10 21:23:15  brouard
                    598:   Summary: Debugging with valgrind
                    599:   Author: Nicolas Brouard
                    600: 
                    601:   Lot of changes in order to output the results with some covariates
                    602:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    603:   improve the code.
                    604:   No more memory valgrind error but a lot has to be done in order to
                    605:   continue the work of splitting the code into subroutines.
                    606:   Also, decodemodel has been improved. Tricode is still not
                    607:   optimal. nbcode should be improved. Documentation has been added in
                    608:   the source code.
                    609: 
1.144     brouard   610:   Revision 1.143  2014/01/26 09:45:38  brouard
                    611:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    612: 
                    613:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    614:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    615: 
1.143     brouard   616:   Revision 1.142  2014/01/26 03:57:36  brouard
                    617:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    618: 
                    619:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    620: 
1.142     brouard   621:   Revision 1.141  2014/01/26 02:42:01  brouard
                    622:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    623: 
1.141     brouard   624:   Revision 1.140  2011/09/02 10:37:54  brouard
                    625:   Summary: times.h is ok with mingw32 now.
                    626: 
1.140     brouard   627:   Revision 1.139  2010/06/14 07:50:17  brouard
                    628:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    629:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    630: 
1.139     brouard   631:   Revision 1.138  2010/04/30 18:19:40  brouard
                    632:   *** empty log message ***
                    633: 
1.138     brouard   634:   Revision 1.137  2010/04/29 18:11:38  brouard
                    635:   (Module): Checking covariates for more complex models
                    636:   than V1+V2. A lot of change to be done. Unstable.
                    637: 
1.137     brouard   638:   Revision 1.136  2010/04/26 20:30:53  brouard
                    639:   (Module): merging some libgsl code. Fixing computation
                    640:   of likelione (using inter/intrapolation if mle = 0) in order to
                    641:   get same likelihood as if mle=1.
                    642:   Some cleaning of code and comments added.
                    643: 
1.136     brouard   644:   Revision 1.135  2009/10/29 15:33:14  brouard
                    645:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    646: 
1.135     brouard   647:   Revision 1.134  2009/10/29 13:18:53  brouard
                    648:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    649: 
1.134     brouard   650:   Revision 1.133  2009/07/06 10:21:25  brouard
                    651:   just nforces
                    652: 
1.133     brouard   653:   Revision 1.132  2009/07/06 08:22:05  brouard
                    654:   Many tings
                    655: 
1.132     brouard   656:   Revision 1.131  2009/06/20 16:22:47  brouard
                    657:   Some dimensions resccaled
                    658: 
1.131     brouard   659:   Revision 1.130  2009/05/26 06:44:34  brouard
                    660:   (Module): Max Covariate is now set to 20 instead of 8. A
                    661:   lot of cleaning with variables initialized to 0. Trying to make
                    662:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    663: 
1.130     brouard   664:   Revision 1.129  2007/08/31 13:49:27  lievre
                    665:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    666: 
1.129     lievre    667:   Revision 1.128  2006/06/30 13:02:05  brouard
                    668:   (Module): Clarifications on computing e.j
                    669: 
1.128     brouard   670:   Revision 1.127  2006/04/28 18:11:50  brouard
                    671:   (Module): Yes the sum of survivors was wrong since
                    672:   imach-114 because nhstepm was no more computed in the age
                    673:   loop. Now we define nhstepma in the age loop.
                    674:   (Module): In order to speed up (in case of numerous covariates) we
                    675:   compute health expectancies (without variances) in a first step
                    676:   and then all the health expectancies with variances or standard
                    677:   deviation (needs data from the Hessian matrices) which slows the
                    678:   computation.
                    679:   In the future we should be able to stop the program is only health
                    680:   expectancies and graph are needed without standard deviations.
                    681: 
1.127     brouard   682:   Revision 1.126  2006/04/28 17:23:28  brouard
                    683:   (Module): Yes the sum of survivors was wrong since
                    684:   imach-114 because nhstepm was no more computed in the age
                    685:   loop. Now we define nhstepma in the age loop.
                    686:   Version 0.98h
                    687: 
1.126     brouard   688:   Revision 1.125  2006/04/04 15:20:31  lievre
                    689:   Errors in calculation of health expectancies. Age was not initialized.
                    690:   Forecasting file added.
                    691: 
                    692:   Revision 1.124  2006/03/22 17:13:53  lievre
                    693:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    694:   The log-likelihood is printed in the log file
                    695: 
                    696:   Revision 1.123  2006/03/20 10:52:43  brouard
                    697:   * imach.c (Module): <title> changed, corresponds to .htm file
                    698:   name. <head> headers where missing.
                    699: 
                    700:   * imach.c (Module): Weights can have a decimal point as for
                    701:   English (a comma might work with a correct LC_NUMERIC environment,
                    702:   otherwise the weight is truncated).
                    703:   Modification of warning when the covariates values are not 0 or
                    704:   1.
                    705:   Version 0.98g
                    706: 
                    707:   Revision 1.122  2006/03/20 09:45:41  brouard
                    708:   (Module): Weights can have a decimal point as for
                    709:   English (a comma might work with a correct LC_NUMERIC environment,
                    710:   otherwise the weight is truncated).
                    711:   Modification of warning when the covariates values are not 0 or
                    712:   1.
                    713:   Version 0.98g
                    714: 
                    715:   Revision 1.121  2006/03/16 17:45:01  lievre
                    716:   * imach.c (Module): Comments concerning covariates added
                    717: 
                    718:   * imach.c (Module): refinements in the computation of lli if
                    719:   status=-2 in order to have more reliable computation if stepm is
                    720:   not 1 month. Version 0.98f
                    721: 
                    722:   Revision 1.120  2006/03/16 15:10:38  lievre
                    723:   (Module): refinements in the computation of lli if
                    724:   status=-2 in order to have more reliable computation if stepm is
                    725:   not 1 month. Version 0.98f
                    726: 
                    727:   Revision 1.119  2006/03/15 17:42:26  brouard
                    728:   (Module): Bug if status = -2, the loglikelihood was
                    729:   computed as likelihood omitting the logarithm. Version O.98e
                    730: 
                    731:   Revision 1.118  2006/03/14 18:20:07  brouard
                    732:   (Module): varevsij Comments added explaining the second
                    733:   table of variances if popbased=1 .
                    734:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    735:   (Module): Function pstamp added
                    736:   (Module): Version 0.98d
                    737: 
                    738:   Revision 1.117  2006/03/14 17:16:22  brouard
                    739:   (Module): varevsij Comments added explaining the second
                    740:   table of variances if popbased=1 .
                    741:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    742:   (Module): Function pstamp added
                    743:   (Module): Version 0.98d
                    744: 
                    745:   Revision 1.116  2006/03/06 10:29:27  brouard
                    746:   (Module): Variance-covariance wrong links and
                    747:   varian-covariance of ej. is needed (Saito).
                    748: 
                    749:   Revision 1.115  2006/02/27 12:17:45  brouard
                    750:   (Module): One freematrix added in mlikeli! 0.98c
                    751: 
                    752:   Revision 1.114  2006/02/26 12:57:58  brouard
                    753:   (Module): Some improvements in processing parameter
                    754:   filename with strsep.
                    755: 
                    756:   Revision 1.113  2006/02/24 14:20:24  brouard
                    757:   (Module): Memory leaks checks with valgrind and:
                    758:   datafile was not closed, some imatrix were not freed and on matrix
                    759:   allocation too.
                    760: 
                    761:   Revision 1.112  2006/01/30 09:55:26  brouard
                    762:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    763: 
                    764:   Revision 1.111  2006/01/25 20:38:18  brouard
                    765:   (Module): Lots of cleaning and bugs added (Gompertz)
                    766:   (Module): Comments can be added in data file. Missing date values
                    767:   can be a simple dot '.'.
                    768: 
                    769:   Revision 1.110  2006/01/25 00:51:50  brouard
                    770:   (Module): Lots of cleaning and bugs added (Gompertz)
                    771: 
                    772:   Revision 1.109  2006/01/24 19:37:15  brouard
                    773:   (Module): Comments (lines starting with a #) are allowed in data.
                    774: 
                    775:   Revision 1.108  2006/01/19 18:05:42  lievre
                    776:   Gnuplot problem appeared...
                    777:   To be fixed
                    778: 
                    779:   Revision 1.107  2006/01/19 16:20:37  brouard
                    780:   Test existence of gnuplot in imach path
                    781: 
                    782:   Revision 1.106  2006/01/19 13:24:36  brouard
                    783:   Some cleaning and links added in html output
                    784: 
                    785:   Revision 1.105  2006/01/05 20:23:19  lievre
                    786:   *** empty log message ***
                    787: 
                    788:   Revision 1.104  2005/09/30 16:11:43  lievre
                    789:   (Module): sump fixed, loop imx fixed, and simplifications.
                    790:   (Module): If the status is missing at the last wave but we know
                    791:   that the person is alive, then we can code his/her status as -2
                    792:   (instead of missing=-1 in earlier versions) and his/her
                    793:   contributions to the likelihood is 1 - Prob of dying from last
                    794:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    795:   the healthy state at last known wave). Version is 0.98
                    796: 
                    797:   Revision 1.103  2005/09/30 15:54:49  lievre
                    798:   (Module): sump fixed, loop imx fixed, and simplifications.
                    799: 
                    800:   Revision 1.102  2004/09/15 17:31:30  brouard
                    801:   Add the possibility to read data file including tab characters.
                    802: 
                    803:   Revision 1.101  2004/09/15 10:38:38  brouard
                    804:   Fix on curr_time
                    805: 
                    806:   Revision 1.100  2004/07/12 18:29:06  brouard
                    807:   Add version for Mac OS X. Just define UNIX in Makefile
                    808: 
                    809:   Revision 1.99  2004/06/05 08:57:40  brouard
                    810:   *** empty log message ***
                    811: 
                    812:   Revision 1.98  2004/05/16 15:05:56  brouard
                    813:   New version 0.97 . First attempt to estimate force of mortality
                    814:   directly from the data i.e. without the need of knowing the health
                    815:   state at each age, but using a Gompertz model: log u =a + b*age .
                    816:   This is the basic analysis of mortality and should be done before any
                    817:   other analysis, in order to test if the mortality estimated from the
                    818:   cross-longitudinal survey is different from the mortality estimated
                    819:   from other sources like vital statistic data.
                    820: 
                    821:   The same imach parameter file can be used but the option for mle should be -3.
                    822: 
1.133     brouard   823:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   824:   former routines in order to include the new code within the former code.
                    825: 
                    826:   The output is very simple: only an estimate of the intercept and of
                    827:   the slope with 95% confident intervals.
                    828: 
                    829:   Current limitations:
                    830:   A) Even if you enter covariates, i.e. with the
                    831:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    832:   B) There is no computation of Life Expectancy nor Life Table.
                    833: 
                    834:   Revision 1.97  2004/02/20 13:25:42  lievre
                    835:   Version 0.96d. Population forecasting command line is (temporarily)
                    836:   suppressed.
                    837: 
                    838:   Revision 1.96  2003/07/15 15:38:55  brouard
                    839:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    840:   rewritten within the same printf. Workaround: many printfs.
                    841: 
                    842:   Revision 1.95  2003/07/08 07:54:34  brouard
                    843:   * imach.c (Repository):
                    844:   (Repository): Using imachwizard code to output a more meaningful covariance
                    845:   matrix (cov(a12,c31) instead of numbers.
                    846: 
                    847:   Revision 1.94  2003/06/27 13:00:02  brouard
                    848:   Just cleaning
                    849: 
                    850:   Revision 1.93  2003/06/25 16:33:55  brouard
                    851:   (Module): On windows (cygwin) function asctime_r doesn't
                    852:   exist so I changed back to asctime which exists.
                    853:   (Module): Version 0.96b
                    854: 
                    855:   Revision 1.92  2003/06/25 16:30:45  brouard
                    856:   (Module): On windows (cygwin) function asctime_r doesn't
                    857:   exist so I changed back to asctime which exists.
                    858: 
                    859:   Revision 1.91  2003/06/25 15:30:29  brouard
                    860:   * imach.c (Repository): Duplicated warning errors corrected.
                    861:   (Repository): Elapsed time after each iteration is now output. It
                    862:   helps to forecast when convergence will be reached. Elapsed time
                    863:   is stamped in powell.  We created a new html file for the graphs
                    864:   concerning matrix of covariance. It has extension -cov.htm.
                    865: 
                    866:   Revision 1.90  2003/06/24 12:34:15  brouard
                    867:   (Module): Some bugs corrected for windows. Also, when
                    868:   mle=-1 a template is output in file "or"mypar.txt with the design
                    869:   of the covariance matrix to be input.
                    870: 
                    871:   Revision 1.89  2003/06/24 12:30:52  brouard
                    872:   (Module): Some bugs corrected for windows. Also, when
                    873:   mle=-1 a template is output in file "or"mypar.txt with the design
                    874:   of the covariance matrix to be input.
                    875: 
                    876:   Revision 1.88  2003/06/23 17:54:56  brouard
                    877:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    878: 
                    879:   Revision 1.87  2003/06/18 12:26:01  brouard
                    880:   Version 0.96
                    881: 
                    882:   Revision 1.86  2003/06/17 20:04:08  brouard
                    883:   (Module): Change position of html and gnuplot routines and added
                    884:   routine fileappend.
                    885: 
                    886:   Revision 1.85  2003/06/17 13:12:43  brouard
                    887:   * imach.c (Repository): Check when date of death was earlier that
                    888:   current date of interview. It may happen when the death was just
                    889:   prior to the death. In this case, dh was negative and likelihood
                    890:   was wrong (infinity). We still send an "Error" but patch by
                    891:   assuming that the date of death was just one stepm after the
                    892:   interview.
                    893:   (Repository): Because some people have very long ID (first column)
                    894:   we changed int to long in num[] and we added a new lvector for
                    895:   memory allocation. But we also truncated to 8 characters (left
                    896:   truncation)
                    897:   (Repository): No more line truncation errors.
                    898: 
                    899:   Revision 1.84  2003/06/13 21:44:43  brouard
                    900:   * imach.c (Repository): Replace "freqsummary" at a correct
                    901:   place. It differs from routine "prevalence" which may be called
                    902:   many times. Probs is memory consuming and must be used with
                    903:   parcimony.
                    904:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    905: 
                    906:   Revision 1.83  2003/06/10 13:39:11  lievre
                    907:   *** empty log message ***
                    908: 
                    909:   Revision 1.82  2003/06/05 15:57:20  brouard
                    910:   Add log in  imach.c and  fullversion number is now printed.
                    911: 
                    912: */
                    913: /*
                    914:    Interpolated Markov Chain
                    915: 
                    916:   Short summary of the programme:
                    917:   
1.227     brouard   918:   This program computes Healthy Life Expectancies or State-specific
                    919:   (if states aren't health statuses) Expectancies from
                    920:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    921: 
                    922:   -1- a first survey ("cross") where individuals from different ages
                    923:   are interviewed on their health status or degree of disability (in
                    924:   the case of a health survey which is our main interest)
                    925: 
                    926:   -2- at least a second wave of interviews ("longitudinal") which
                    927:   measure each change (if any) in individual health status.  Health
                    928:   expectancies are computed from the time spent in each health state
                    929:   according to a model. More health states you consider, more time is
                    930:   necessary to reach the Maximum Likelihood of the parameters involved
                    931:   in the model.  The simplest model is the multinomial logistic model
                    932:   where pij is the probability to be observed in state j at the second
                    933:   wave conditional to be observed in state i at the first
                    934:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    935:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    936:   have a more complex model than "constant and age", you should modify
                    937:   the program where the markup *Covariates have to be included here
                    938:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   939:   convergence.
                    940: 
                    941:   The advantage of this computer programme, compared to a simple
                    942:   multinomial logistic model, is clear when the delay between waves is not
                    943:   identical for each individual. Also, if a individual missed an
                    944:   intermediate interview, the information is lost, but taken into
                    945:   account using an interpolation or extrapolation.  
                    946: 
                    947:   hPijx is the probability to be observed in state i at age x+h
                    948:   conditional to the observed state i at age x. The delay 'h' can be
                    949:   split into an exact number (nh*stepm) of unobserved intermediate
                    950:   states. This elementary transition (by month, quarter,
                    951:   semester or year) is modelled as a multinomial logistic.  The hPx
                    952:   matrix is simply the matrix product of nh*stepm elementary matrices
                    953:   and the contribution of each individual to the likelihood is simply
                    954:   hPijx.
                    955: 
                    956:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   957:   of the life expectancies. It also computes the period (stable) prevalence.
                    958: 
                    959: Back prevalence and projections:
1.227     brouard   960: 
                    961:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    962:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    963:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    964:    mobilavproj)
                    965: 
                    966:     Computes the back prevalence limit for any combination of
                    967:     covariate values k at any age between ageminpar and agemaxpar and
                    968:     returns it in **bprlim. In the loops,
                    969: 
                    970:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    971:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    972: 
                    973:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   974:    Computes for any combination of covariates k and any age between bage and fage 
                    975:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    976:                        oldm=oldms;savm=savms;
1.227     brouard   977: 
1.267     brouard   978:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   979:      Computes the transition matrix starting at age 'age' over
                    980:      'nhstepm*hstepm*stepm' months (i.e. until
                    981:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard   982:      nhstepm*hstepm matrices. 
                    983: 
                    984:      Returns p3mat[i][j][h] after calling
                    985:      p3mat[i][j][h]=matprod2(newm,
                    986:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                    987:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                    988:      oldm);
1.226     brouard   989: 
                    990: Important routines
                    991: 
                    992: - func (or funcone), computes logit (pij) distinguishing
                    993:   o fixed variables (single or product dummies or quantitative);
                    994:   o varying variables by:
                    995:    (1) wave (single, product dummies, quantitative), 
                    996:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                    997:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                    998:        % varying dummy (not done) or quantitative (not done);
                    999: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                   1000:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                   1001: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                   1002:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                   1003:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard  1004: 
1.226     brouard  1005: 
                   1006:   
1.133     brouard  1007:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                   1008:            Institut national d'études démographiques, Paris.
1.126     brouard  1009:   This software have been partly granted by Euro-REVES, a concerted action
                   1010:   from the European Union.
                   1011:   It is copyrighted identically to a GNU software product, ie programme and
                   1012:   software can be distributed freely for non commercial use. Latest version
                   1013:   can be accessed at http://euroreves.ined.fr/imach .
                   1014: 
                   1015:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                   1016:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                   1017:   
                   1018:   **********************************************************************/
                   1019: /*
                   1020:   main
                   1021:   read parameterfile
                   1022:   read datafile
                   1023:   concatwav
                   1024:   freqsummary
                   1025:   if (mle >= 1)
                   1026:     mlikeli
                   1027:   print results files
                   1028:   if mle==1 
                   1029:      computes hessian
                   1030:   read end of parameter file: agemin, agemax, bage, fage, estepm
                   1031:       begin-prev-date,...
                   1032:   open gnuplot file
                   1033:   open html file
1.145     brouard  1034:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                   1035:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                   1036:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                   1037:     freexexit2 possible for memory heap.
                   1038: 
                   1039:   h Pij x                         | pij_nom  ficrestpij
                   1040:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                   1041:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                   1042:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                   1043: 
                   1044:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                   1045:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                   1046:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                   1047:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                   1048:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                   1049: 
1.126     brouard  1050:   forecasting if prevfcast==1 prevforecast call prevalence()
                   1051:   health expectancies
                   1052:   Variance-covariance of DFLE
                   1053:   prevalence()
                   1054:    movingaverage()
                   1055:   varevsij() 
                   1056:   if popbased==1 varevsij(,popbased)
                   1057:   total life expectancies
                   1058:   Variance of period (stable) prevalence
                   1059:  end
                   1060: */
                   1061: 
1.187     brouard  1062: /* #define DEBUG */
                   1063: /* #define DEBUGBRENT */
1.203     brouard  1064: /* #define DEBUGLINMIN */
                   1065: /* #define DEBUGHESS */
                   1066: #define DEBUGHESSIJ
1.224     brouard  1067: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard  1068: #define POWELL /* Instead of NLOPT */
1.224     brouard  1069: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard  1070: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                   1071: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard  1072: 
                   1073: #include <math.h>
                   1074: #include <stdio.h>
                   1075: #include <stdlib.h>
                   1076: #include <string.h>
1.226     brouard  1077: #include <ctype.h>
1.159     brouard  1078: 
                   1079: #ifdef _WIN32
                   1080: #include <io.h>
1.172     brouard  1081: #include <windows.h>
                   1082: #include <tchar.h>
1.159     brouard  1083: #else
1.126     brouard  1084: #include <unistd.h>
1.159     brouard  1085: #endif
1.126     brouard  1086: 
                   1087: #include <limits.h>
                   1088: #include <sys/types.h>
1.171     brouard  1089: 
                   1090: #if defined(__GNUC__)
                   1091: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1092: #endif
                   1093: 
1.126     brouard  1094: #include <sys/stat.h>
                   1095: #include <errno.h>
1.159     brouard  1096: /* extern int errno; */
1.126     brouard  1097: 
1.157     brouard  1098: /* #ifdef LINUX */
                   1099: /* #include <time.h> */
                   1100: /* #include "timeval.h" */
                   1101: /* #else */
                   1102: /* #include <sys/time.h> */
                   1103: /* #endif */
                   1104: 
1.126     brouard  1105: #include <time.h>
                   1106: 
1.136     brouard  1107: #ifdef GSL
                   1108: #include <gsl/gsl_errno.h>
                   1109: #include <gsl/gsl_multimin.h>
                   1110: #endif
                   1111: 
1.167     brouard  1112: 
1.162     brouard  1113: #ifdef NLOPT
                   1114: #include <nlopt.h>
                   1115: typedef struct {
                   1116:   double (* function)(double [] );
                   1117: } myfunc_data ;
                   1118: #endif
                   1119: 
1.126     brouard  1120: /* #include <libintl.h> */
                   1121: /* #define _(String) gettext (String) */
                   1122: 
1.251     brouard  1123: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1124: 
                   1125: #define GNUPLOTPROGRAM "gnuplot"
                   1126: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1127: #define FILENAMELENGTH 132
                   1128: 
                   1129: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1130: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1131: 
1.144     brouard  1132: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1133: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1134: 
                   1135: #define NINTERVMAX 8
1.144     brouard  1136: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1137: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.291     brouard  1138: #define NCOVMAX 20  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1139: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1140: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1141: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1142: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1143: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1144: /* #define AGESUP 130 */
1.288     brouard  1145: /* #define AGESUP 150 */
                   1146: #define AGESUP 200
1.268     brouard  1147: #define AGEINF 0
1.218     brouard  1148: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1149: #define AGEBASE 40
1.194     brouard  1150: #define AGEOVERFLOW 1.e20
1.164     brouard  1151: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1152: #ifdef _WIN32
                   1153: #define DIRSEPARATOR '\\'
                   1154: #define CHARSEPARATOR "\\"
                   1155: #define ODIRSEPARATOR '/'
                   1156: #else
1.126     brouard  1157: #define DIRSEPARATOR '/'
                   1158: #define CHARSEPARATOR "/"
                   1159: #define ODIRSEPARATOR '\\'
                   1160: #endif
                   1161: 
1.311   ! brouard  1162: /* $Id: imach.c,v 1.310 2022/03/17 08:45:53 brouard Exp $ */
1.126     brouard  1163: /* $State: Exp $ */
1.196     brouard  1164: #include "version.h"
                   1165: char version[]=__IMACH_VERSION__;
1.308     brouard  1166: char copyright[]="March 2021,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2020, Nihon University 2021, INED 2000-2021";
1.311   ! brouard  1167: char fullversion[]="$Revision: 1.310 $ $Date: 2022/03/17 08:45:53 $"; 
1.126     brouard  1168: char strstart[80];
                   1169: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1170: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1171: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1172: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1173: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1174: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1175: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1176: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1177: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1178: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1179: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1180: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1181: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1182: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1183: int nsd=0; /**< Total number of single dummy variables (output) */
                   1184: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1185: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1186: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1187: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1188: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1189: int cptcov=0; /* Working variable */
1.290     brouard  1190: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1191: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.302     brouard  1192: int npar=NPARMAX; /* Number of parameters (nlstate+ndeath-1)*nlstate*ncovmodel; */
1.126     brouard  1193: int nlstate=2; /* Number of live states */
                   1194: int ndeath=1; /* Number of dead states */
1.130     brouard  1195: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1196: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1197: int popbased=0;
                   1198: 
                   1199: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1200: int maxwav=0; /* Maxim number of waves */
                   1201: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1202: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1203: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1204:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1205: int mle=1, weightopt=0;
1.126     brouard  1206: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1207: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1208: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1209:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1210: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1211: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1212: 
1.130     brouard  1213: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1214: double **matprod2(); /* test */
1.126     brouard  1215: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1216: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1217: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1218: 
1.136     brouard  1219: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1220: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1221: FILE *ficlog, *ficrespow;
1.130     brouard  1222: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1223: double fretone; /* Only one call to likelihood */
1.130     brouard  1224: long ipmx=0; /* Number of contributions */
1.126     brouard  1225: double sw; /* Sum of weights */
                   1226: char filerespow[FILENAMELENGTH];
                   1227: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1228: FILE *ficresilk;
                   1229: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1230: FILE *ficresprobmorprev;
                   1231: FILE *fichtm, *fichtmcov; /* Html File */
                   1232: FILE *ficreseij;
                   1233: char filerese[FILENAMELENGTH];
                   1234: FILE *ficresstdeij;
                   1235: char fileresstde[FILENAMELENGTH];
                   1236: FILE *ficrescveij;
                   1237: char filerescve[FILENAMELENGTH];
                   1238: FILE  *ficresvij;
                   1239: char fileresv[FILENAMELENGTH];
1.269     brouard  1240: 
1.126     brouard  1241: char title[MAXLINE];
1.234     brouard  1242: char model[MAXLINE]; /**< The model line */
1.217     brouard  1243: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1244: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1245: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1246: char command[FILENAMELENGTH];
                   1247: int  outcmd=0;
                   1248: 
1.217     brouard  1249: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1250: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1251: char filelog[FILENAMELENGTH]; /* Log file */
                   1252: char filerest[FILENAMELENGTH];
                   1253: char fileregp[FILENAMELENGTH];
                   1254: char popfile[FILENAMELENGTH];
                   1255: 
                   1256: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1257: 
1.157     brouard  1258: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1259: /* struct timezone tzp; */
                   1260: /* extern int gettimeofday(); */
                   1261: struct tm tml, *gmtime(), *localtime();
                   1262: 
                   1263: extern time_t time();
                   1264: 
                   1265: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1266: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1267: struct tm tm;
                   1268: 
1.126     brouard  1269: char strcurr[80], strfor[80];
                   1270: 
                   1271: char *endptr;
                   1272: long lval;
                   1273: double dval;
                   1274: 
                   1275: #define NR_END 1
                   1276: #define FREE_ARG char*
                   1277: #define FTOL 1.0e-10
                   1278: 
                   1279: #define NRANSI 
1.240     brouard  1280: #define ITMAX 200
                   1281: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1282: 
                   1283: #define TOL 2.0e-4 
                   1284: 
                   1285: #define CGOLD 0.3819660 
                   1286: #define ZEPS 1.0e-10 
                   1287: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1288: 
                   1289: #define GOLD 1.618034 
                   1290: #define GLIMIT 100.0 
                   1291: #define TINY 1.0e-20 
                   1292: 
                   1293: static double maxarg1,maxarg2;
                   1294: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1295: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1296:   
                   1297: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1298: #define rint(a) floor(a+0.5)
1.166     brouard  1299: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1300: #define mytinydouble 1.0e-16
1.166     brouard  1301: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1302: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1303: /* static double dsqrarg; */
                   1304: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1305: static double sqrarg;
                   1306: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1307: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1308: int agegomp= AGEGOMP;
                   1309: 
                   1310: int imx; 
                   1311: int stepm=1;
                   1312: /* Stepm, step in month: minimum step interpolation*/
                   1313: 
                   1314: int estepm;
                   1315: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1316: 
                   1317: int m,nb;
                   1318: long *num;
1.197     brouard  1319: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1320: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1321:                   covariate for which somebody answered excluding 
                   1322:                   undefined. Usually 2: 0 and 1. */
                   1323: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1324:                             covariate for which somebody answered including 
                   1325:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1326: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1327: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1328: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1329: double *ageexmed,*agecens;
                   1330: double dateintmean=0;
1.296     brouard  1331:   double anprojd, mprojd, jprojd; /* For eventual projections */
                   1332:   double anprojf, mprojf, jprojf;
1.126     brouard  1333: 
1.296     brouard  1334:   double anbackd, mbackd, jbackd; /* For eventual backprojections */
                   1335:   double anbackf, mbackf, jbackf;
                   1336:   double jintmean,mintmean,aintmean;  
1.126     brouard  1337: double *weight;
                   1338: int **s; /* Status */
1.141     brouard  1339: double *agedc;
1.145     brouard  1340: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1341:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1342:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1343: double **coqvar; /* Fixed quantitative covariate nqv */
                   1344: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1345: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1346: double  idx; 
                   1347: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1348: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1349: /*k          1  2   3   4     5    6    7     8    9 */
                   1350: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1351: /* Tndvar[k]    1   2   3               4          5 */
                   1352: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1353: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1354: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1355: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1356: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1357: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1358: /* Tprod[i]=k           4               7            */
                   1359: /* Tage[i]=k                  5               8      */
                   1360: /* */
                   1361: /* Type                    */
                   1362: /* V         1  2  3  4  5 */
                   1363: /*           F  F  V  V  V */
                   1364: /*           D  Q  D  D  Q */
                   1365: /*                         */
                   1366: int *TvarsD;
                   1367: int *TvarsDind;
                   1368: int *TvarsQ;
                   1369: int *TvarsQind;
                   1370: 
1.235     brouard  1371: #define MAXRESULTLINES 10
                   1372: int nresult=0;
1.258     brouard  1373: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1374: int TKresult[MAXRESULTLINES];
1.237     brouard  1375: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1376: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1377: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1378: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1379: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1380: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1381: 
1.234     brouard  1382: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1383: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1384: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1385: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1386: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1387: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1388: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1389: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1390: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1391: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1392: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1393: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1394: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1395: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1396: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1397: 
1.230     brouard  1398: int *Tvarsel; /**< Selected covariates for output */
                   1399: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1400: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1401: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1402: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1403: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1404: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1405: int *Tage;
1.227     brouard  1406: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1407: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1408: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1409: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1410: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1411: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1412: int **Tvard;
                   1413: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1414: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1415: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1416:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1417:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1418: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1419: double *lsurv, *lpop, *tpop;
                   1420: 
1.231     brouard  1421: #define FD 1; /* Fixed dummy covariate */
                   1422: #define FQ 2; /* Fixed quantitative covariate */
                   1423: #define FP 3; /* Fixed product covariate */
                   1424: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1425: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1426: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1427: #define VD 10; /* Varying dummy covariate */
                   1428: #define VQ 11; /* Varying quantitative covariate */
                   1429: #define VP 12; /* Varying product covariate */
                   1430: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1431: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1432: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1433: #define APFD 16; /* Age product * fixed dummy covariate */
                   1434: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1435: #define APVD 18; /* Age product * varying dummy covariate */
                   1436: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1437: 
                   1438: #define FTYPE 1; /* Fixed covariate */
                   1439: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1440: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1441: 
                   1442: struct kmodel{
                   1443:        int maintype; /* main type */
                   1444:        int subtype; /* subtype */
                   1445: };
                   1446: struct kmodel modell[NCOVMAX];
                   1447: 
1.143     brouard  1448: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1449: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1450: 
                   1451: /**************** split *************************/
                   1452: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1453: {
                   1454:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1455:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1456:   */ 
                   1457:   char *ss;                            /* pointer */
1.186     brouard  1458:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1459: 
                   1460:   l1 = strlen(path );                  /* length of path */
                   1461:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1462:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1463:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1464:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1465:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1466:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1467:     /* get current working directory */
                   1468:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1469: #ifdef WIN32
                   1470:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1471: #else
                   1472:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1473: #endif
1.126     brouard  1474:       return( GLOCK_ERROR_GETCWD );
                   1475:     }
                   1476:     /* got dirc from getcwd*/
                   1477:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1478:   } else {                             /* strip directory from path */
1.126     brouard  1479:     ss++;                              /* after this, the filename */
                   1480:     l2 = strlen( ss );                 /* length of filename */
                   1481:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1482:     strcpy( name, ss );                /* save file name */
                   1483:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1484:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1485:     printf(" DIRC2 = %s \n",dirc);
                   1486:   }
                   1487:   /* We add a separator at the end of dirc if not exists */
                   1488:   l1 = strlen( dirc );                 /* length of directory */
                   1489:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1490:     dirc[l1] =  DIRSEPARATOR;
                   1491:     dirc[l1+1] = 0; 
                   1492:     printf(" DIRC3 = %s \n",dirc);
                   1493:   }
                   1494:   ss = strrchr( name, '.' );           /* find last / */
                   1495:   if (ss >0){
                   1496:     ss++;
                   1497:     strcpy(ext,ss);                    /* save extension */
                   1498:     l1= strlen( name);
                   1499:     l2= strlen(ss)+1;
                   1500:     strncpy( finame, name, l1-l2);
                   1501:     finame[l1-l2]= 0;
                   1502:   }
                   1503: 
                   1504:   return( 0 );                         /* we're done */
                   1505: }
                   1506: 
                   1507: 
                   1508: /******************************************/
                   1509: 
                   1510: void replace_back_to_slash(char *s, char*t)
                   1511: {
                   1512:   int i;
                   1513:   int lg=0;
                   1514:   i=0;
                   1515:   lg=strlen(t);
                   1516:   for(i=0; i<= lg; i++) {
                   1517:     (s[i] = t[i]);
                   1518:     if (t[i]== '\\') s[i]='/';
                   1519:   }
                   1520: }
                   1521: 
1.132     brouard  1522: char *trimbb(char *out, char *in)
1.137     brouard  1523: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1524:   char *s;
                   1525:   s=out;
                   1526:   while (*in != '\0'){
1.137     brouard  1527:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1528:       in++;
                   1529:     }
                   1530:     *out++ = *in++;
                   1531:   }
                   1532:   *out='\0';
                   1533:   return s;
                   1534: }
                   1535: 
1.187     brouard  1536: /* char *substrchaine(char *out, char *in, char *chain) */
                   1537: /* { */
                   1538: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1539: /*   char *s, *t; */
                   1540: /*   t=in;s=out; */
                   1541: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1542: /*     *out++ = *in++; */
                   1543: /*   } */
                   1544: 
                   1545: /*   /\* *in matches *chain *\/ */
                   1546: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1547: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1548: /*   } */
                   1549: /*   in--; chain--; */
                   1550: /*   while ( (*in != '\0')){ */
                   1551: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1552: /*     *out++ = *in++; */
                   1553: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1554: /*   } */
                   1555: /*   *out='\0'; */
                   1556: /*   out=s; */
                   1557: /*   return out; */
                   1558: /* } */
                   1559: char *substrchaine(char *out, char *in, char *chain)
                   1560: {
                   1561:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1562:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1563: 
                   1564:   char *strloc;
                   1565: 
                   1566:   strcpy (out, in); 
                   1567:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1568:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1569:   if(strloc != NULL){ 
                   1570:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1571:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1572:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1573:   }
                   1574:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1575:   return out;
                   1576: }
                   1577: 
                   1578: 
1.145     brouard  1579: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1580: {
1.187     brouard  1581:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1582:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.310     brouard  1583:      gives alocc="abcdef" and blocc="ghi2j".
1.145     brouard  1584:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1585:   */
1.160     brouard  1586:   char *s, *t;
1.145     brouard  1587:   t=in;s=in;
                   1588:   while ((*in != occ) && (*in != '\0')){
                   1589:     *alocc++ = *in++;
                   1590:   }
                   1591:   if( *in == occ){
                   1592:     *(alocc)='\0';
                   1593:     s=++in;
                   1594:   }
                   1595:  
                   1596:   if (s == t) {/* occ not found */
                   1597:     *(alocc-(in-s))='\0';
                   1598:     in=s;
                   1599:   }
                   1600:   while ( *in != '\0'){
                   1601:     *blocc++ = *in++;
                   1602:   }
                   1603: 
                   1604:   *blocc='\0';
                   1605:   return t;
                   1606: }
1.137     brouard  1607: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1608: {
1.187     brouard  1609:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1610:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1611:      gives blocc="abcdef2ghi" and alocc="j".
                   1612:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1613:   */
                   1614:   char *s, *t;
                   1615:   t=in;s=in;
                   1616:   while (*in != '\0'){
                   1617:     while( *in == occ){
                   1618:       *blocc++ = *in++;
                   1619:       s=in;
                   1620:     }
                   1621:     *blocc++ = *in++;
                   1622:   }
                   1623:   if (s == t) /* occ not found */
                   1624:     *(blocc-(in-s))='\0';
                   1625:   else
                   1626:     *(blocc-(in-s)-1)='\0';
                   1627:   in=s;
                   1628:   while ( *in != '\0'){
                   1629:     *alocc++ = *in++;
                   1630:   }
                   1631: 
                   1632:   *alocc='\0';
                   1633:   return s;
                   1634: }
                   1635: 
1.126     brouard  1636: int nbocc(char *s, char occ)
                   1637: {
                   1638:   int i,j=0;
                   1639:   int lg=20;
                   1640:   i=0;
                   1641:   lg=strlen(s);
                   1642:   for(i=0; i<= lg; i++) {
1.234     brouard  1643:     if  (s[i] == occ ) j++;
1.126     brouard  1644:   }
                   1645:   return j;
                   1646: }
                   1647: 
1.137     brouard  1648: /* void cutv(char *u,char *v, char*t, char occ) */
                   1649: /* { */
                   1650: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1651: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1652: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1653: /*   int i,lg,j,p=0; */
                   1654: /*   i=0; */
                   1655: /*   lg=strlen(t); */
                   1656: /*   for(j=0; j<=lg-1; j++) { */
                   1657: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1658: /*   } */
1.126     brouard  1659: 
1.137     brouard  1660: /*   for(j=0; j<p; j++) { */
                   1661: /*     (u[j] = t[j]); */
                   1662: /*   } */
                   1663: /*      u[p]='\0'; */
1.126     brouard  1664: 
1.137     brouard  1665: /*    for(j=0; j<= lg; j++) { */
                   1666: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1667: /*   } */
                   1668: /* } */
1.126     brouard  1669: 
1.160     brouard  1670: #ifdef _WIN32
                   1671: char * strsep(char **pp, const char *delim)
                   1672: {
                   1673:   char *p, *q;
                   1674:          
                   1675:   if ((p = *pp) == NULL)
                   1676:     return 0;
                   1677:   if ((q = strpbrk (p, delim)) != NULL)
                   1678:   {
                   1679:     *pp = q + 1;
                   1680:     *q = '\0';
                   1681:   }
                   1682:   else
                   1683:     *pp = 0;
                   1684:   return p;
                   1685: }
                   1686: #endif
                   1687: 
1.126     brouard  1688: /********************** nrerror ********************/
                   1689: 
                   1690: void nrerror(char error_text[])
                   1691: {
                   1692:   fprintf(stderr,"ERREUR ...\n");
                   1693:   fprintf(stderr,"%s\n",error_text);
                   1694:   exit(EXIT_FAILURE);
                   1695: }
                   1696: /*********************** vector *******************/
                   1697: double *vector(int nl, int nh)
                   1698: {
                   1699:   double *v;
                   1700:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1701:   if (!v) nrerror("allocation failure in vector");
                   1702:   return v-nl+NR_END;
                   1703: }
                   1704: 
                   1705: /************************ free vector ******************/
                   1706: void free_vector(double*v, int nl, int nh)
                   1707: {
                   1708:   free((FREE_ARG)(v+nl-NR_END));
                   1709: }
                   1710: 
                   1711: /************************ivector *******************************/
                   1712: int *ivector(long nl,long nh)
                   1713: {
                   1714:   int *v;
                   1715:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1716:   if (!v) nrerror("allocation failure in ivector");
                   1717:   return v-nl+NR_END;
                   1718: }
                   1719: 
                   1720: /******************free ivector **************************/
                   1721: void free_ivector(int *v, long nl, long nh)
                   1722: {
                   1723:   free((FREE_ARG)(v+nl-NR_END));
                   1724: }
                   1725: 
                   1726: /************************lvector *******************************/
                   1727: long *lvector(long nl,long nh)
                   1728: {
                   1729:   long *v;
                   1730:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1731:   if (!v) nrerror("allocation failure in ivector");
                   1732:   return v-nl+NR_END;
                   1733: }
                   1734: 
                   1735: /******************free lvector **************************/
                   1736: void free_lvector(long *v, long nl, long nh)
                   1737: {
                   1738:   free((FREE_ARG)(v+nl-NR_END));
                   1739: }
                   1740: 
                   1741: /******************* imatrix *******************************/
                   1742: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1743:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1744: { 
                   1745:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1746:   int **m; 
                   1747:   
                   1748:   /* allocate pointers to rows */ 
                   1749:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1750:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1751:   m += NR_END; 
                   1752:   m -= nrl; 
                   1753:   
                   1754:   
                   1755:   /* allocate rows and set pointers to them */ 
                   1756:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1757:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1758:   m[nrl] += NR_END; 
                   1759:   m[nrl] -= ncl; 
                   1760:   
                   1761:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1762:   
                   1763:   /* return pointer to array of pointers to rows */ 
                   1764:   return m; 
                   1765: } 
                   1766: 
                   1767: /****************** free_imatrix *************************/
                   1768: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1769:       int **m;
                   1770:       long nch,ncl,nrh,nrl; 
                   1771:      /* free an int matrix allocated by imatrix() */ 
                   1772: { 
                   1773:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1774:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1775: } 
                   1776: 
                   1777: /******************* matrix *******************************/
                   1778: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1779: {
                   1780:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1781:   double **m;
                   1782: 
                   1783:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1784:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1785:   m += NR_END;
                   1786:   m -= nrl;
                   1787: 
                   1788:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1789:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1790:   m[nrl] += NR_END;
                   1791:   m[nrl] -= ncl;
                   1792: 
                   1793:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1794:   return m;
1.145     brouard  1795:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1796: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1797: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1798:    */
                   1799: }
                   1800: 
                   1801: /*************************free matrix ************************/
                   1802: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1803: {
                   1804:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1805:   free((FREE_ARG)(m+nrl-NR_END));
                   1806: }
                   1807: 
                   1808: /******************* ma3x *******************************/
                   1809: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1810: {
                   1811:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1812:   double ***m;
                   1813: 
                   1814:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1815:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1816:   m += NR_END;
                   1817:   m -= nrl;
                   1818: 
                   1819:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1820:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1821:   m[nrl] += NR_END;
                   1822:   m[nrl] -= ncl;
                   1823: 
                   1824:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1825: 
                   1826:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1827:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1828:   m[nrl][ncl] += NR_END;
                   1829:   m[nrl][ncl] -= nll;
                   1830:   for (j=ncl+1; j<=nch; j++) 
                   1831:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1832:   
                   1833:   for (i=nrl+1; i<=nrh; i++) {
                   1834:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1835:     for (j=ncl+1; j<=nch; j++) 
                   1836:       m[i][j]=m[i][j-1]+nlay;
                   1837:   }
                   1838:   return m; 
                   1839:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1840:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1841:   */
                   1842: }
                   1843: 
                   1844: /*************************free ma3x ************************/
                   1845: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1846: {
                   1847:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1848:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1849:   free((FREE_ARG)(m+nrl-NR_END));
                   1850: }
                   1851: 
                   1852: /*************** function subdirf ***********/
                   1853: char *subdirf(char fileres[])
                   1854: {
                   1855:   /* Caution optionfilefiname is hidden */
                   1856:   strcpy(tmpout,optionfilefiname);
                   1857:   strcat(tmpout,"/"); /* Add to the right */
                   1858:   strcat(tmpout,fileres);
                   1859:   return tmpout;
                   1860: }
                   1861: 
                   1862: /*************** function subdirf2 ***********/
                   1863: char *subdirf2(char fileres[], char *preop)
                   1864: {
                   1865:   
                   1866:   /* Caution optionfilefiname is hidden */
                   1867:   strcpy(tmpout,optionfilefiname);
                   1868:   strcat(tmpout,"/");
                   1869:   strcat(tmpout,preop);
                   1870:   strcat(tmpout,fileres);
                   1871:   return tmpout;
                   1872: }
                   1873: 
                   1874: /*************** function subdirf3 ***********/
                   1875: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1876: {
                   1877:   
                   1878:   /* Caution optionfilefiname is hidden */
                   1879:   strcpy(tmpout,optionfilefiname);
                   1880:   strcat(tmpout,"/");
                   1881:   strcat(tmpout,preop);
                   1882:   strcat(tmpout,preop2);
                   1883:   strcat(tmpout,fileres);
                   1884:   return tmpout;
                   1885: }
1.213     brouard  1886:  
                   1887: /*************** function subdirfext ***********/
                   1888: char *subdirfext(char fileres[], char *preop, char *postop)
                   1889: {
                   1890:   
                   1891:   strcpy(tmpout,preop);
                   1892:   strcat(tmpout,fileres);
                   1893:   strcat(tmpout,postop);
                   1894:   return tmpout;
                   1895: }
1.126     brouard  1896: 
1.213     brouard  1897: /*************** function subdirfext3 ***********/
                   1898: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1899: {
                   1900:   
                   1901:   /* Caution optionfilefiname is hidden */
                   1902:   strcpy(tmpout,optionfilefiname);
                   1903:   strcat(tmpout,"/");
                   1904:   strcat(tmpout,preop);
                   1905:   strcat(tmpout,fileres);
                   1906:   strcat(tmpout,postop);
                   1907:   return tmpout;
                   1908: }
                   1909:  
1.162     brouard  1910: char *asc_diff_time(long time_sec, char ascdiff[])
                   1911: {
                   1912:   long sec_left, days, hours, minutes;
                   1913:   days = (time_sec) / (60*60*24);
                   1914:   sec_left = (time_sec) % (60*60*24);
                   1915:   hours = (sec_left) / (60*60) ;
                   1916:   sec_left = (sec_left) %(60*60);
                   1917:   minutes = (sec_left) /60;
                   1918:   sec_left = (sec_left) % (60);
                   1919:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1920:   return ascdiff;
                   1921: }
                   1922: 
1.126     brouard  1923: /***************** f1dim *************************/
                   1924: extern int ncom; 
                   1925: extern double *pcom,*xicom;
                   1926: extern double (*nrfunc)(double []); 
                   1927:  
                   1928: double f1dim(double x) 
                   1929: { 
                   1930:   int j; 
                   1931:   double f;
                   1932:   double *xt; 
                   1933:  
                   1934:   xt=vector(1,ncom); 
                   1935:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1936:   f=(*nrfunc)(xt); 
                   1937:   free_vector(xt,1,ncom); 
                   1938:   return f; 
                   1939: } 
                   1940: 
                   1941: /*****************brent *************************/
                   1942: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1943: {
                   1944:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1945:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1946:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1947:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1948:    * returned function value. 
                   1949:   */
1.126     brouard  1950:   int iter; 
                   1951:   double a,b,d,etemp;
1.159     brouard  1952:   double fu=0,fv,fw,fx;
1.164     brouard  1953:   double ftemp=0.;
1.126     brouard  1954:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1955:   double e=0.0; 
                   1956:  
                   1957:   a=(ax < cx ? ax : cx); 
                   1958:   b=(ax > cx ? ax : cx); 
                   1959:   x=w=v=bx; 
                   1960:   fw=fv=fx=(*f)(x); 
                   1961:   for (iter=1;iter<=ITMAX;iter++) { 
                   1962:     xm=0.5*(a+b); 
                   1963:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1964:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1965:     printf(".");fflush(stdout);
                   1966:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1967: #ifdef DEBUGBRENT
1.126     brouard  1968:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1969:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1970:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1971: #endif
                   1972:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1973:       *xmin=x; 
                   1974:       return fx; 
                   1975:     } 
                   1976:     ftemp=fu;
                   1977:     if (fabs(e) > tol1) { 
                   1978:       r=(x-w)*(fx-fv); 
                   1979:       q=(x-v)*(fx-fw); 
                   1980:       p=(x-v)*q-(x-w)*r; 
                   1981:       q=2.0*(q-r); 
                   1982:       if (q > 0.0) p = -p; 
                   1983:       q=fabs(q); 
                   1984:       etemp=e; 
                   1985:       e=d; 
                   1986:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  1987:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  1988:       else { 
1.224     brouard  1989:                                d=p/q; 
                   1990:                                u=x+d; 
                   1991:                                if (u-a < tol2 || b-u < tol2) 
                   1992:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  1993:       } 
                   1994:     } else { 
                   1995:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   1996:     } 
                   1997:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   1998:     fu=(*f)(u); 
                   1999:     if (fu <= fx) { 
                   2000:       if (u >= x) a=x; else b=x; 
                   2001:       SHFT(v,w,x,u) 
1.183     brouard  2002:       SHFT(fv,fw,fx,fu) 
                   2003:     } else { 
                   2004:       if (u < x) a=u; else b=u; 
                   2005:       if (fu <= fw || w == x) { 
1.224     brouard  2006:                                v=w; 
                   2007:                                w=u; 
                   2008:                                fv=fw; 
                   2009:                                fw=fu; 
1.183     brouard  2010:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  2011:                                v=u; 
                   2012:                                fv=fu; 
1.183     brouard  2013:       } 
                   2014:     } 
1.126     brouard  2015:   } 
                   2016:   nrerror("Too many iterations in brent"); 
                   2017:   *xmin=x; 
                   2018:   return fx; 
                   2019: } 
                   2020: 
                   2021: /****************** mnbrak ***********************/
                   2022: 
                   2023: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   2024:            double (*func)(double)) 
1.183     brouard  2025: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   2026: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   2027: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   2028: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   2029:    */
1.126     brouard  2030:   double ulim,u,r,q, dum;
                   2031:   double fu; 
1.187     brouard  2032: 
                   2033:   double scale=10.;
                   2034:   int iterscale=0;
                   2035: 
                   2036:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   2037:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   2038: 
                   2039: 
                   2040:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   2041:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   2042:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   2043:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   2044:   /* } */
                   2045: 
1.126     brouard  2046:   if (*fb > *fa) { 
                   2047:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  2048:     SHFT(dum,*fb,*fa,dum) 
                   2049:   } 
1.126     brouard  2050:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   2051:   *fc=(*func)(*cx); 
1.183     brouard  2052: #ifdef DEBUG
1.224     brouard  2053:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   2054:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  2055: #endif
1.224     brouard  2056:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  2057:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  2058:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  2059:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  2060:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   2061:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   2062:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  2063:       fu=(*func)(u); 
1.163     brouard  2064: #ifdef DEBUG
                   2065:       /* f(x)=A(x-u)**2+f(u) */
                   2066:       double A, fparabu; 
                   2067:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2068:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  2069:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   2070:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  2071:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   2072:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   2073:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   2074:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  2075: #endif 
1.184     brouard  2076: #ifdef MNBRAKORIGINAL
1.183     brouard  2077: #else
1.191     brouard  2078: /*       if (fu > *fc) { */
                   2079: /* #ifdef DEBUG */
                   2080: /*       printf("mnbrak4  fu > fc \n"); */
                   2081: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   2082: /* #endif */
                   2083: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2084: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2085: /*     dum=u; /\* Shifting c and u *\/ */
                   2086: /*     u = *cx; */
                   2087: /*     *cx = dum; */
                   2088: /*     dum = fu; */
                   2089: /*     fu = *fc; */
                   2090: /*     *fc =dum; */
                   2091: /*       } else { /\* end *\/ */
                   2092: /* #ifdef DEBUG */
                   2093: /*       printf("mnbrak3  fu < fc \n"); */
                   2094: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2095: /* #endif */
                   2096: /*     dum=u; /\* Shifting c and u *\/ */
                   2097: /*     u = *cx; */
                   2098: /*     *cx = dum; */
                   2099: /*     dum = fu; */
                   2100: /*     fu = *fc; */
                   2101: /*     *fc =dum; */
                   2102: /*       } */
1.224     brouard  2103: #ifdef DEBUGMNBRAK
                   2104:                 double A, fparabu; 
                   2105:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2106:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2107:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2108:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2109: #endif
1.191     brouard  2110:       dum=u; /* Shifting c and u */
                   2111:       u = *cx;
                   2112:       *cx = dum;
                   2113:       dum = fu;
                   2114:       fu = *fc;
                   2115:       *fc =dum;
1.183     brouard  2116: #endif
1.162     brouard  2117:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2118: #ifdef DEBUG
1.224     brouard  2119:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2120:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2121: #endif
1.126     brouard  2122:       fu=(*func)(u); 
                   2123:       if (fu < *fc) { 
1.183     brouard  2124: #ifdef DEBUG
1.224     brouard  2125:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2126:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2127: #endif
                   2128:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2129:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2130: #ifdef DEBUG
                   2131:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2132: #endif
                   2133:       } 
1.162     brouard  2134:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2135: #ifdef DEBUG
1.224     brouard  2136:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2137:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2138: #endif
1.126     brouard  2139:       u=ulim; 
                   2140:       fu=(*func)(u); 
1.183     brouard  2141:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2142: #ifdef DEBUG
1.224     brouard  2143:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2144:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2145: #endif
1.126     brouard  2146:       u=(*cx)+GOLD*(*cx-*bx); 
                   2147:       fu=(*func)(u); 
1.224     brouard  2148: #ifdef DEBUG
                   2149:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2150:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2151: #endif
1.183     brouard  2152:     } /* end tests */
1.126     brouard  2153:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2154:     SHFT(*fa,*fb,*fc,fu) 
                   2155: #ifdef DEBUG
1.224     brouard  2156:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2157:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2158: #endif
                   2159:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2160: } 
                   2161: 
                   2162: /*************** linmin ************************/
1.162     brouard  2163: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2164: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2165: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2166: the value of func at the returned location p . This is actually all accomplished by calling the
                   2167: routines mnbrak and brent .*/
1.126     brouard  2168: int ncom; 
                   2169: double *pcom,*xicom;
                   2170: double (*nrfunc)(double []); 
                   2171:  
1.224     brouard  2172: #ifdef LINMINORIGINAL
1.126     brouard  2173: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2174: #else
                   2175: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2176: #endif
1.126     brouard  2177: { 
                   2178:   double brent(double ax, double bx, double cx, 
                   2179:               double (*f)(double), double tol, double *xmin); 
                   2180:   double f1dim(double x); 
                   2181:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2182:              double *fc, double (*func)(double)); 
                   2183:   int j; 
                   2184:   double xx,xmin,bx,ax; 
                   2185:   double fx,fb,fa;
1.187     brouard  2186: 
1.203     brouard  2187: #ifdef LINMINORIGINAL
                   2188: #else
                   2189:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2190: #endif
                   2191:   
1.126     brouard  2192:   ncom=n; 
                   2193:   pcom=vector(1,n); 
                   2194:   xicom=vector(1,n); 
                   2195:   nrfunc=func; 
                   2196:   for (j=1;j<=n;j++) { 
                   2197:     pcom[j]=p[j]; 
1.202     brouard  2198:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2199:   } 
1.187     brouard  2200: 
1.203     brouard  2201: #ifdef LINMINORIGINAL
                   2202:   xx=1.;
                   2203: #else
                   2204:   axs=0.0;
                   2205:   xxs=1.;
                   2206:   do{
                   2207:     xx= xxs;
                   2208: #endif
1.187     brouard  2209:     ax=0.;
                   2210:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2211:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2212:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2213:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2214:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2215:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2216:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2217: #ifdef LINMINORIGINAL
                   2218: #else
                   2219:     if (fx != fx){
1.224     brouard  2220:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2221:                        printf("|");
                   2222:                        fprintf(ficlog,"|");
1.203     brouard  2223: #ifdef DEBUGLINMIN
1.224     brouard  2224:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2225: #endif
                   2226:     }
1.224     brouard  2227:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2228: #endif
                   2229:   
1.191     brouard  2230: #ifdef DEBUGLINMIN
                   2231:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2232:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2233: #endif
1.224     brouard  2234: #ifdef LINMINORIGINAL
                   2235: #else
                   2236:        if(fb == fx){ /* Flat function in the direction */
                   2237:                xmin=xx;
                   2238:     *flat=1;
                   2239:        }else{
                   2240:     *flat=0;
                   2241: #endif
                   2242:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2243:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2244:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2245:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2246:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2247:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2248: #ifdef DEBUG
1.224     brouard  2249:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2250:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2251: #endif
                   2252: #ifdef LINMINORIGINAL
                   2253: #else
                   2254:                        }
1.126     brouard  2255: #endif
1.191     brouard  2256: #ifdef DEBUGLINMIN
                   2257:   printf("linmin end ");
1.202     brouard  2258:   fprintf(ficlog,"linmin end ");
1.191     brouard  2259: #endif
1.126     brouard  2260:   for (j=1;j<=n;j++) { 
1.203     brouard  2261: #ifdef LINMINORIGINAL
                   2262:     xi[j] *= xmin; 
                   2263: #else
                   2264: #ifdef DEBUGLINMIN
                   2265:     if(xxs <1.0)
                   2266:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2267: #endif
                   2268:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2269: #ifdef DEBUGLINMIN
                   2270:     if(xxs <1.0)
                   2271:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2272: #endif
                   2273: #endif
1.187     brouard  2274:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2275:   } 
1.191     brouard  2276: #ifdef DEBUGLINMIN
1.203     brouard  2277:   printf("\n");
1.191     brouard  2278:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2279:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2280:   for (j=1;j<=n;j++) { 
1.202     brouard  2281:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2282:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2283:     if(j % ncovmodel == 0){
1.191     brouard  2284:       printf("\n");
1.202     brouard  2285:       fprintf(ficlog,"\n");
                   2286:     }
1.191     brouard  2287:   }
1.203     brouard  2288: #else
1.191     brouard  2289: #endif
1.126     brouard  2290:   free_vector(xicom,1,n); 
                   2291:   free_vector(pcom,1,n); 
                   2292: } 
                   2293: 
                   2294: 
                   2295: /*************** powell ************************/
1.162     brouard  2296: /*
                   2297: Minimization of a function func of n variables. Input consists of an initial starting point
                   2298: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2299: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2300: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2301: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2302: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2303:  */
1.224     brouard  2304: #ifdef LINMINORIGINAL
                   2305: #else
                   2306:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2307:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2308: #endif
1.126     brouard  2309: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2310:            double (*func)(double [])) 
                   2311: { 
1.224     brouard  2312: #ifdef LINMINORIGINAL
                   2313:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2314:              double (*func)(double [])); 
1.224     brouard  2315: #else 
1.241     brouard  2316:  void linmin(double p[], double xi[], int n, double *fret,
                   2317:             double (*func)(double []),int *flat); 
1.224     brouard  2318: #endif
1.239     brouard  2319:  int i,ibig,j,jk,k; 
1.126     brouard  2320:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2321:   double directest;
1.126     brouard  2322:   double fp,fptt;
                   2323:   double *xits;
                   2324:   int niterf, itmp;
1.224     brouard  2325: #ifdef LINMINORIGINAL
                   2326: #else
                   2327: 
                   2328:   flatdir=ivector(1,n); 
                   2329:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2330: #endif
1.126     brouard  2331: 
                   2332:   pt=vector(1,n); 
                   2333:   ptt=vector(1,n); 
                   2334:   xit=vector(1,n); 
                   2335:   xits=vector(1,n); 
                   2336:   *fret=(*func)(p); 
                   2337:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2338:   rcurr_time = time(NULL);  
1.126     brouard  2339:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2340:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2341:     ibig=0; 
                   2342:     del=0.0; 
1.157     brouard  2343:     rlast_time=rcurr_time;
                   2344:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2345:     rcurr_time = time(NULL);  
                   2346:     curr_time = *localtime(&rcurr_time);
                   2347:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2348:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2349: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2350:     for (i=1;i<=n;i++) {
1.126     brouard  2351:       fprintf(ficrespow," %.12lf", p[i]);
                   2352:     }
1.239     brouard  2353:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2354:     printf("\n#model=  1      +     age ");
                   2355:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2356:     if(nagesqr==1){
1.241     brouard  2357:        printf("  + age*age  ");
                   2358:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2359:     }
                   2360:     for(j=1;j <=ncovmodel-2;j++){
                   2361:       if(Typevar[j]==0) {
                   2362:        printf("  +      V%d  ",Tvar[j]);
                   2363:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2364:       }else if(Typevar[j]==1) {
                   2365:        printf("  +    V%d*age ",Tvar[j]);
                   2366:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2367:       }else if(Typevar[j]==2) {
                   2368:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2369:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2370:       }
                   2371:     }
1.126     brouard  2372:     printf("\n");
1.239     brouard  2373: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2374: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2375:     fprintf(ficlog,"\n");
1.239     brouard  2376:     for(i=1,jk=1; i <=nlstate; i++){
                   2377:       for(k=1; k <=(nlstate+ndeath); k++){
                   2378:        if (k != i) {
                   2379:          printf("%d%d ",i,k);
                   2380:          fprintf(ficlog,"%d%d ",i,k);
                   2381:          for(j=1; j <=ncovmodel; j++){
                   2382:            printf("%12.7f ",p[jk]);
                   2383:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2384:            jk++; 
                   2385:          }
                   2386:          printf("\n");
                   2387:          fprintf(ficlog,"\n");
                   2388:        }
                   2389:       }
                   2390:     }
1.241     brouard  2391:     if(*iter <=3 && *iter >1){
1.157     brouard  2392:       tml = *localtime(&rcurr_time);
                   2393:       strcpy(strcurr,asctime(&tml));
                   2394:       rforecast_time=rcurr_time; 
1.126     brouard  2395:       itmp = strlen(strcurr);
                   2396:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2397:        strcurr[itmp-1]='\0';
1.162     brouard  2398:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2399:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2400:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2401:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2402:        forecast_time = *localtime(&rforecast_time);
                   2403:        strcpy(strfor,asctime(&forecast_time));
                   2404:        itmp = strlen(strfor);
                   2405:        if(strfor[itmp-1]=='\n')
                   2406:          strfor[itmp-1]='\0';
                   2407:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2408:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2409:       }
                   2410:     }
1.187     brouard  2411:     for (i=1;i<=n;i++) { /* For each direction i */
                   2412:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2413:       fptt=(*fret); 
                   2414: #ifdef DEBUG
1.203     brouard  2415:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2416:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2417: #endif
1.203     brouard  2418:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2419:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2420: #ifdef LINMINORIGINAL
1.188     brouard  2421:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2422: #else
                   2423:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2424:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2425: #endif
                   2426:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2427:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2428:                                /* because that direction will be replaced unless the gain del is small */
                   2429:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2430:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2431:                                /* with the new direction. */
                   2432:                                del=fabs(fptt-(*fret)); 
                   2433:                                ibig=i; 
1.126     brouard  2434:       } 
                   2435: #ifdef DEBUG
                   2436:       printf("%d %.12e",i,(*fret));
                   2437:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2438:       for (j=1;j<=n;j++) {
1.224     brouard  2439:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2440:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2441:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2442:       }
                   2443:       for(j=1;j<=n;j++) {
1.225     brouard  2444:                                printf(" p(%d)=%.12e",j,p[j]);
                   2445:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2446:       }
                   2447:       printf("\n");
                   2448:       fprintf(ficlog,"\n");
                   2449: #endif
1.187     brouard  2450:     } /* end loop on each direction i */
                   2451:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2452:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2453:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2454:       for(j=1;j<=n;j++) {
1.302     brouard  2455:        if(flatdir[j] >0){
                   2456:          printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2457:          fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2458:        }
                   2459:        /* printf("\n"); */
                   2460:        /* fprintf(ficlog,"\n"); */
                   2461:       }
1.243     brouard  2462:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2463:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2464:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2465:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2466:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2467:       /* decreased of more than 3.84  */
                   2468:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2469:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2470:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2471:                        
1.188     brouard  2472:       /* Starting the program with initial values given by a former maximization will simply change */
                   2473:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2474:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2475:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2476: #ifdef DEBUG
                   2477:       int k[2],l;
                   2478:       k[0]=1;
                   2479:       k[1]=-1;
                   2480:       printf("Max: %.12e",(*func)(p));
                   2481:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2482:       for (j=1;j<=n;j++) {
                   2483:        printf(" %.12e",p[j]);
                   2484:        fprintf(ficlog," %.12e",p[j]);
                   2485:       }
                   2486:       printf("\n");
                   2487:       fprintf(ficlog,"\n");
                   2488:       for(l=0;l<=1;l++) {
                   2489:        for (j=1;j<=n;j++) {
                   2490:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2491:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2492:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2493:        }
                   2494:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2495:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2496:       }
                   2497: #endif
                   2498: 
1.224     brouard  2499: #ifdef LINMINORIGINAL
                   2500: #else
                   2501:       free_ivector(flatdir,1,n); 
                   2502: #endif
1.126     brouard  2503:       free_vector(xit,1,n); 
                   2504:       free_vector(xits,1,n); 
                   2505:       free_vector(ptt,1,n); 
                   2506:       free_vector(pt,1,n); 
                   2507:       return; 
1.192     brouard  2508:     } /* enough precision */ 
1.240     brouard  2509:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2510:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2511:       ptt[j]=2.0*p[j]-pt[j]; 
                   2512:       xit[j]=p[j]-pt[j]; 
                   2513:       pt[j]=p[j]; 
                   2514:     } 
1.181     brouard  2515:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2516: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2517:                if (*iter <=4) {
1.225     brouard  2518: #else
                   2519: #endif
1.224     brouard  2520: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2521: #else
1.161     brouard  2522:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2523: #endif
1.162     brouard  2524:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2525:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2526:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2527:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2528:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2529:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2530:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2531:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2532:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2533:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2534:       /* mu² and del² are equal when f3=f1 */
                   2535:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2536:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2537:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2538:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2539: #ifdef NRCORIGINAL
                   2540:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2541: #else
                   2542:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2543:       t= t- del*SQR(fp-fptt);
1.183     brouard  2544: #endif
1.202     brouard  2545:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2546: #ifdef DEBUG
1.181     brouard  2547:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2548:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2549:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2550:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2551:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2552:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2553:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2554:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2555: #endif
1.183     brouard  2556: #ifdef POWELLORIGINAL
                   2557:       if (t < 0.0) { /* Then we use it for new direction */
                   2558: #else
1.182     brouard  2559:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2560:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2561:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2562:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2563:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2564:       } 
1.181     brouard  2565:       if (directest < 0.0) { /* Then we use it for new direction */
                   2566: #endif
1.191     brouard  2567: #ifdef DEBUGLINMIN
1.234     brouard  2568:        printf("Before linmin in direction P%d-P0\n",n);
                   2569:        for (j=1;j<=n;j++) {
                   2570:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2571:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2572:          if(j % ncovmodel == 0){
                   2573:            printf("\n");
                   2574:            fprintf(ficlog,"\n");
                   2575:          }
                   2576:        }
1.224     brouard  2577: #endif
                   2578: #ifdef LINMINORIGINAL
1.234     brouard  2579:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2580: #else
1.234     brouard  2581:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2582:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2583: #endif
1.234     brouard  2584:        
1.191     brouard  2585: #ifdef DEBUGLINMIN
1.234     brouard  2586:        for (j=1;j<=n;j++) { 
                   2587:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2588:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2589:          if(j % ncovmodel == 0){
                   2590:            printf("\n");
                   2591:            fprintf(ficlog,"\n");
                   2592:          }
                   2593:        }
1.224     brouard  2594: #endif
1.234     brouard  2595:        for (j=1;j<=n;j++) { 
                   2596:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2597:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2598:        }
1.224     brouard  2599: #ifdef LINMINORIGINAL
                   2600: #else
1.234     brouard  2601:        for (j=1, flatd=0;j<=n;j++) {
                   2602:          if(flatdir[j]>0)
                   2603:            flatd++;
                   2604:        }
                   2605:        if(flatd >0){
1.255     brouard  2606:          printf("%d flat directions: ",flatd);
                   2607:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2608:          for (j=1;j<=n;j++) { 
                   2609:            if(flatdir[j]>0){
                   2610:              printf("%d ",j);
                   2611:              fprintf(ficlog,"%d ",j);
                   2612:            }
                   2613:          }
                   2614:          printf("\n");
                   2615:          fprintf(ficlog,"\n");
                   2616:        }
1.191     brouard  2617: #endif
1.234     brouard  2618:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2619:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2620:        
1.126     brouard  2621: #ifdef DEBUG
1.234     brouard  2622:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2623:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2624:        for(j=1;j<=n;j++){
                   2625:          printf(" %lf",xit[j]);
                   2626:          fprintf(ficlog," %lf",xit[j]);
                   2627:        }
                   2628:        printf("\n");
                   2629:        fprintf(ficlog,"\n");
1.126     brouard  2630: #endif
1.192     brouard  2631:       } /* end of t or directest negative */
1.224     brouard  2632: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2633: #else
1.234     brouard  2634:       } /* end if (fptt < fp)  */
1.192     brouard  2635: #endif
1.225     brouard  2636: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2637:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2638: #else
1.224     brouard  2639: #endif
1.234     brouard  2640:                } /* loop iteration */ 
1.126     brouard  2641: } 
1.234     brouard  2642:   
1.126     brouard  2643: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2644:   
1.235     brouard  2645:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2646:   {
1.279     brouard  2647:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2648:      *   (and selected quantitative values in nres)
                   2649:      *  by left multiplying the unit
                   2650:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2651:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2652:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2653:      * or prevalence in state 1, prevalence in state 2, 0
                   2654:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2655:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2656:      * Output is prlim.
                   2657:      * Initial matrix pimij 
                   2658:      */
1.206     brouard  2659:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2660:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2661:   /*  0,                   0                  , 1} */
                   2662:   /*
                   2663:    * and after some iteration: */
                   2664:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2665:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2666:   /*  0,                   0                  , 1} */
                   2667:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2668:   /* {0.51571254859325999, 0.4842874514067399, */
                   2669:   /*  0.51326036147820708, 0.48673963852179264} */
                   2670:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2671:     
1.126     brouard  2672:   int i, ii,j,k;
1.209     brouard  2673:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2674:   /* double **matprod2(); */ /* test */
1.218     brouard  2675:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2676:   double **newm;
1.209     brouard  2677:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2678:   int ncvloop=0;
1.288     brouard  2679:   int first=0;
1.169     brouard  2680:   
1.209     brouard  2681:   min=vector(1,nlstate);
                   2682:   max=vector(1,nlstate);
                   2683:   meandiff=vector(1,nlstate);
                   2684: 
1.218     brouard  2685:        /* Starting with matrix unity */
1.126     brouard  2686:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2687:     for (j=1;j<=nlstate+ndeath;j++){
                   2688:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2689:     }
1.169     brouard  2690:   
                   2691:   cov[1]=1.;
                   2692:   
                   2693:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2694:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2695:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2696:     ncvloop++;
1.126     brouard  2697:     newm=savm;
                   2698:     /* Covariates have to be included here again */
1.138     brouard  2699:     cov[2]=agefin;
1.187     brouard  2700:     if(nagesqr==1)
                   2701:       cov[3]= agefin*agefin;;
1.234     brouard  2702:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2703:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2704:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2705:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2706:     }
                   2707:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2708:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2709:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2710:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2711:     }
1.237     brouard  2712:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2713:       if(Dummy[Tvar[Tage[k]]]){
                   2714:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2715:       } else{
1.235     brouard  2716:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2717:       }
1.235     brouard  2718:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2719:     }
1.237     brouard  2720:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2721:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2722:       if(Dummy[Tvard[k][1]==0]){
                   2723:        if(Dummy[Tvard[k][2]==0]){
                   2724:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2725:        }else{
                   2726:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2727:        }
                   2728:       }else{
                   2729:        if(Dummy[Tvard[k][2]==0]){
                   2730:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2731:        }else{
                   2732:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2733:        }
                   2734:       }
1.234     brouard  2735:     }
1.138     brouard  2736:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2737:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2738:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2739:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2740:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2741:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2742:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2743:     
1.126     brouard  2744:     savm=oldm;
                   2745:     oldm=newm;
1.209     brouard  2746: 
                   2747:     for(j=1; j<=nlstate; j++){
                   2748:       max[j]=0.;
                   2749:       min[j]=1.;
                   2750:     }
                   2751:     for(i=1;i<=nlstate;i++){
                   2752:       sumnew=0;
                   2753:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2754:       for(j=1; j<=nlstate; j++){ 
                   2755:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2756:        max[j]=FMAX(max[j],prlim[i][j]);
                   2757:        min[j]=FMIN(min[j],prlim[i][j]);
                   2758:       }
                   2759:     }
                   2760: 
1.126     brouard  2761:     maxmax=0.;
1.209     brouard  2762:     for(j=1; j<=nlstate; j++){
                   2763:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2764:       maxmax=FMAX(maxmax,meandiff[j]);
                   2765:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2766:     } /* j loop */
1.203     brouard  2767:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2768:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2769:     if(maxmax < ftolpl){
1.209     brouard  2770:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2771:       free_vector(min,1,nlstate);
                   2772:       free_vector(max,1,nlstate);
                   2773:       free_vector(meandiff,1,nlstate);
1.126     brouard  2774:       return prlim;
                   2775:     }
1.288     brouard  2776:   } /* agefin loop */
1.208     brouard  2777:     /* After some age loop it doesn't converge */
1.288     brouard  2778:   if(!first){
                   2779:     first=1;
                   2780:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2781:   }
                   2782:   fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2783: 
1.209     brouard  2784:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2785:   free_vector(min,1,nlstate);
                   2786:   free_vector(max,1,nlstate);
                   2787:   free_vector(meandiff,1,nlstate);
1.208     brouard  2788:   
1.169     brouard  2789:   return prlim; /* should not reach here */
1.126     brouard  2790: }
                   2791: 
1.217     brouard  2792: 
                   2793:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2794: 
1.218     brouard  2795:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2796:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2797:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2798: {
1.264     brouard  2799:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2800:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2801:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2802:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2803:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2804:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2805:   /* Initial matrix pimij */
                   2806:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2807:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2808:   /*  0,                   0                  , 1} */
                   2809:   /*
                   2810:    * and after some iteration: */
                   2811:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2812:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2813:   /*  0,                   0                  , 1} */
                   2814:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2815:   /* {0.51571254859325999, 0.4842874514067399, */
                   2816:   /*  0.51326036147820708, 0.48673963852179264} */
                   2817:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2818: 
                   2819:   int i, ii,j,k;
1.247     brouard  2820:   int first=0;
1.217     brouard  2821:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2822:   /* double **matprod2(); */ /* test */
                   2823:   double **out, cov[NCOVMAX+1], **bmij();
                   2824:   double **newm;
1.218     brouard  2825:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2826:   double        **oldm, **savm;  /* for use */
                   2827: 
1.217     brouard  2828:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2829:   int ncvloop=0;
                   2830:   
                   2831:   min=vector(1,nlstate);
                   2832:   max=vector(1,nlstate);
                   2833:   meandiff=vector(1,nlstate);
                   2834: 
1.266     brouard  2835:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2836:   oldm=oldms; savm=savms;
                   2837:   
                   2838:   /* Starting with matrix unity */
                   2839:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2840:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2841:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2842:     }
                   2843:   
                   2844:   cov[1]=1.;
                   2845:   
                   2846:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2847:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2848:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2849:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2850:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2851:     ncvloop++;
1.218     brouard  2852:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2853:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2854:     /* Covariates have to be included here again */
                   2855:     cov[2]=agefin;
                   2856:     if(nagesqr==1)
                   2857:       cov[3]= agefin*agefin;;
1.242     brouard  2858:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2859:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2860:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2861:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2862:     }
                   2863:     /* for (k=1; k<=cptcovn;k++) { */
                   2864:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2865:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2866:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2867:     /* } */
                   2868:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2869:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2870:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2871:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2872:     }
                   2873:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2874:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2875:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2876:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2877:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2878:       if(Dummy[Tvar[Tage[k]]]){
                   2879:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2880:       } else{
                   2881:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2882:       }
                   2883:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2884:     }
                   2885:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2886:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2887:       if(Dummy[Tvard[k][1]==0]){
                   2888:        if(Dummy[Tvard[k][2]==0]){
                   2889:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2890:        }else{
                   2891:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2892:        }
                   2893:       }else{
                   2894:        if(Dummy[Tvard[k][2]==0]){
                   2895:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2896:        }else{
                   2897:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2898:        }
                   2899:       }
1.217     brouard  2900:     }
                   2901:     
                   2902:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2903:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2904:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2905:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2906:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2907:                /* ij should be linked to the correct index of cov */
                   2908:                /* age and covariate values ij are in 'cov', but we need to pass
                   2909:                 * ij for the observed prevalence at age and status and covariate
                   2910:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2911:                 */
                   2912:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2913:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2914:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2915:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2916:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2917:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2918:     /*         printf("%d newm= ",i); */
                   2919:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2920:     /*           printf("%f ",newm[i][j]); */
                   2921:     /*         } */
                   2922:     /*         printf("oldm * "); */
                   2923:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2924:     /*           printf("%f ",oldm[i][j]); */
                   2925:     /*         } */
1.268     brouard  2926:     /*         printf(" bmmij "); */
1.266     brouard  2927:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2928:     /*           printf("%f ",pmmij[i][j]); */
                   2929:     /*         } */
                   2930:     /*         printf("\n"); */
                   2931:     /*   } */
                   2932:     /* } */
1.217     brouard  2933:     savm=oldm;
                   2934:     oldm=newm;
1.266     brouard  2935: 
1.217     brouard  2936:     for(j=1; j<=nlstate; j++){
                   2937:       max[j]=0.;
                   2938:       min[j]=1.;
                   2939:     }
                   2940:     for(j=1; j<=nlstate; j++){ 
                   2941:       for(i=1;i<=nlstate;i++){
1.234     brouard  2942:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2943:        bprlim[i][j]= newm[i][j];
                   2944:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2945:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2946:       }
                   2947:     }
1.218     brouard  2948:                
1.217     brouard  2949:     maxmax=0.;
                   2950:     for(i=1; i<=nlstate; i++){
                   2951:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2952:       maxmax=FMAX(maxmax,meandiff[i]);
                   2953:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2954:     } /* i loop */
1.217     brouard  2955:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2956:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2957:     if(maxmax < ftolpl){
1.220     brouard  2958:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2959:       free_vector(min,1,nlstate);
                   2960:       free_vector(max,1,nlstate);
                   2961:       free_vector(meandiff,1,nlstate);
                   2962:       return bprlim;
                   2963:     }
1.288     brouard  2964:   } /* agefin loop */
1.217     brouard  2965:     /* After some age loop it doesn't converge */
1.288     brouard  2966:   if(!first){
1.247     brouard  2967:     first=1;
                   2968:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2969: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2970:   }
                   2971:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2972: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2973:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2974:   free_vector(min,1,nlstate);
                   2975:   free_vector(max,1,nlstate);
                   2976:   free_vector(meandiff,1,nlstate);
                   2977:   
                   2978:   return bprlim; /* should not reach here */
                   2979: }
                   2980: 
1.126     brouard  2981: /*************** transition probabilities ***************/ 
                   2982: 
                   2983: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   2984: {
1.138     brouard  2985:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  2986:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  2987:      model to the ncovmodel covariates (including constant and age).
                   2988:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   2989:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   2990:      ncth covariate in the global vector x is given by the formula:
                   2991:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   2992:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   2993:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   2994:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  2995:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  2996:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  2997:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  2998:   */
                   2999:   double s1, lnpijopii;
1.126     brouard  3000:   /*double t34;*/
1.164     brouard  3001:   int i,j, nc, ii, jj;
1.126     brouard  3002: 
1.223     brouard  3003:   for(i=1; i<= nlstate; i++){
                   3004:     for(j=1; j<i;j++){
                   3005:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3006:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3007:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3008:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3009:       }
                   3010:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3011:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3012:     }
                   3013:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3014:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3015:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3016:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3017:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3018:       }
                   3019:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3020:     }
                   3021:   }
1.218     brouard  3022:   
1.223     brouard  3023:   for(i=1; i<= nlstate; i++){
                   3024:     s1=0;
                   3025:     for(j=1; j<i; j++){
                   3026:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3027:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3028:     }
                   3029:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3030:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3031:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3032:     }
                   3033:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3034:     ps[i][i]=1./(s1+1.);
                   3035:     /* Computing other pijs */
                   3036:     for(j=1; j<i; j++)
                   3037:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3038:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3039:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3040:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3041:   } /* end i */
1.218     brouard  3042:   
1.223     brouard  3043:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3044:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3045:       ps[ii][jj]=0;
                   3046:       ps[ii][ii]=1;
                   3047:     }
                   3048:   }
1.294     brouard  3049: 
                   3050: 
1.223     brouard  3051:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3052:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3053:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3054:   /*   } */
                   3055:   /*   printf("\n "); */
                   3056:   /* } */
                   3057:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3058:   /*
                   3059:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  3060:                goto end;*/
1.266     brouard  3061:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  3062: }
                   3063: 
1.218     brouard  3064: /*************** backward transition probabilities ***************/ 
                   3065: 
                   3066:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3067: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3068:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   3069: {
1.302     brouard  3070:   /* Computes the backward probability at age agefin, cov[2], and covariate combination 'ij'. In fact cov is already filled and x too.
1.266     brouard  3071:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  3072:    */
1.218     brouard  3073:   int i, ii, j,k;
1.222     brouard  3074:   
                   3075:   double **out, **pmij();
                   3076:   double sumnew=0.;
1.218     brouard  3077:   double agefin;
1.292     brouard  3078:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  3079:   double **dnewm, **dsavm, **doldm;
                   3080:   double **bbmij;
                   3081:   
1.218     brouard  3082:   doldm=ddoldms; /* global pointers */
1.222     brouard  3083:   dnewm=ddnewms;
                   3084:   dsavm=ddsavms;
                   3085:   
                   3086:   agefin=cov[2];
1.268     brouard  3087:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3088:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3089:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3090:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3091: 
                   3092:   /* P_x */
1.266     brouard  3093:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3094:   /* outputs pmmij which is a stochastic matrix in row */
                   3095: 
                   3096:   /* Diag(w_x) */
1.292     brouard  3097:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3098:   sumnew=0.;
1.269     brouard  3099:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3100:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.297     brouard  3101:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]); */
1.268     brouard  3102:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3103:   }
                   3104:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3105:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3106:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3107:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3108:     }
                   3109:   }else{
                   3110:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3111:       for (j=1;j<=nlstate+ndeath;j++)
                   3112:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3113:     }
                   3114:     /* if(sumnew <0.9){ */
                   3115:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3116:     /* } */
                   3117:   }
                   3118:   k3=0.0;  /* We put the last diagonal to 0 */
                   3119:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3120:       doldm[ii][ii]= k3;
                   3121:   }
                   3122:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3123:   
1.292     brouard  3124:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
                   3125:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3126: 
1.292     brouard  3127:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3128:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3129:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3130:     sumnew=0.;
1.222     brouard  3131:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3132:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3133:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3134:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3135:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3136:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3137:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3138:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3139:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3140:        /* }else */
1.268     brouard  3141:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3142:     } /*End ii */
                   3143:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3144: 
1.292     brouard  3145:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3146:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3147:   /* end bmij */
1.266     brouard  3148:   return ps; /*pointer is unchanged */
1.218     brouard  3149: }
1.217     brouard  3150: /*************** transition probabilities ***************/ 
                   3151: 
1.218     brouard  3152: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3153: {
                   3154:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3155:      computes the probability to be observed in state j being in state i by appying the
                   3156:      model to the ncovmodel covariates (including constant and age).
                   3157:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3158:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3159:      ncth covariate in the global vector x is given by the formula:
                   3160:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3161:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3162:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3163:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3164:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3165:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3166:   */
                   3167:   double s1, lnpijopii;
                   3168:   /*double t34;*/
                   3169:   int i,j, nc, ii, jj;
                   3170: 
1.234     brouard  3171:   for(i=1; i<= nlstate; i++){
                   3172:     for(j=1; j<i;j++){
                   3173:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3174:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3175:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3176:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3177:       }
                   3178:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3179:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3180:     }
                   3181:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3182:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3183:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3184:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3185:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3186:       }
                   3187:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3188:     }
                   3189:   }
                   3190:   
                   3191:   for(i=1; i<= nlstate; i++){
                   3192:     s1=0;
                   3193:     for(j=1; j<i; j++){
                   3194:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3195:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3196:     }
                   3197:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3198:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3199:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3200:     }
                   3201:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3202:     ps[i][i]=1./(s1+1.);
                   3203:     /* Computing other pijs */
                   3204:     for(j=1; j<i; j++)
                   3205:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3206:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3207:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3208:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3209:   } /* end i */
                   3210:   
                   3211:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3212:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3213:       ps[ii][jj]=0;
                   3214:       ps[ii][ii]=1;
                   3215:     }
                   3216:   }
1.296     brouard  3217:   /* Added for prevbcast */ /* Transposed matrix too */
1.234     brouard  3218:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3219:     s1=0.;
                   3220:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3221:       s1+=ps[ii][jj];
                   3222:     }
                   3223:     for(ii=1; ii<= nlstate; ii++){
                   3224:       ps[ii][jj]=ps[ii][jj]/s1;
                   3225:     }
                   3226:   }
                   3227:   /* Transposition */
                   3228:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3229:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3230:       s1=ps[ii][jj];
                   3231:       ps[ii][jj]=ps[jj][ii];
                   3232:       ps[jj][ii]=s1;
                   3233:     }
                   3234:   }
                   3235:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3236:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3237:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3238:   /*   } */
                   3239:   /*   printf("\n "); */
                   3240:   /* } */
                   3241:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3242:   /*
                   3243:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3244:     goto end;*/
                   3245:   return ps;
1.217     brouard  3246: }
                   3247: 
                   3248: 
1.126     brouard  3249: /**************** Product of 2 matrices ******************/
                   3250: 
1.145     brouard  3251: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3252: {
                   3253:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3254:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3255:   /* in, b, out are matrice of pointers which should have been initialized 
                   3256:      before: only the contents of out is modified. The function returns
                   3257:      a pointer to pointers identical to out */
1.145     brouard  3258:   int i, j, k;
1.126     brouard  3259:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3260:     for(k=ncolol; k<=ncoloh; k++){
                   3261:       out[i][k]=0.;
                   3262:       for(j=ncl; j<=nch; j++)
                   3263:        out[i][k] +=in[i][j]*b[j][k];
                   3264:     }
1.126     brouard  3265:   return out;
                   3266: }
                   3267: 
                   3268: 
                   3269: /************* Higher Matrix Product ***************/
                   3270: 
1.235     brouard  3271: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3272: {
1.218     brouard  3273:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3274:      'nhstepm*hstepm*stepm' months (i.e. until
                   3275:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3276:      nhstepm*hstepm matrices. 
                   3277:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3278:      (typically every 2 years instead of every month which is too big 
                   3279:      for the memory).
                   3280:      Model is determined by parameters x and covariates have to be 
                   3281:      included manually here. 
                   3282: 
                   3283:      */
                   3284: 
                   3285:   int i, j, d, h, k;
1.131     brouard  3286:   double **out, cov[NCOVMAX+1];
1.126     brouard  3287:   double **newm;
1.187     brouard  3288:   double agexact;
1.214     brouard  3289:   double agebegin, ageend;
1.126     brouard  3290: 
                   3291:   /* Hstepm could be zero and should return the unit matrix */
                   3292:   for (i=1;i<=nlstate+ndeath;i++)
                   3293:     for (j=1;j<=nlstate+ndeath;j++){
                   3294:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3295:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3296:     }
                   3297:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3298:   for(h=1; h <=nhstepm; h++){
                   3299:     for(d=1; d <=hstepm; d++){
                   3300:       newm=savm;
                   3301:       /* Covariates have to be included here again */
                   3302:       cov[1]=1.;
1.214     brouard  3303:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3304:       cov[2]=agexact;
                   3305:       if(nagesqr==1)
1.227     brouard  3306:        cov[3]= agexact*agexact;
1.235     brouard  3307:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3308:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3309:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3310:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3311:       }
                   3312:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3313:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3314:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3315:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3316:       }
                   3317:       for (k=1; k<=cptcovage;k++){
                   3318:        if(Dummy[Tvar[Tage[k]]]){
                   3319:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3320:        } else{
                   3321:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3322:        }
                   3323:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3324:       }
                   3325:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3326:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3327:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3328:       }
                   3329:       /* for (k=1; k<=cptcovn;k++)  */
                   3330:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3331:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3332:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3333:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3334:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3335:       
                   3336:       
1.126     brouard  3337:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3338:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3339:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3340:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3341:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3342:       /* if((int)age == 70){ */
                   3343:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3344:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3345:       /*         printf("%d pmmij ",i); */
                   3346:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3347:       /*           printf("%f ",pmmij[i][j]); */
                   3348:       /*         } */
                   3349:       /*         printf(" oldm "); */
                   3350:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3351:       /*           printf("%f ",oldm[i][j]); */
                   3352:       /*         } */
                   3353:       /*         printf("\n"); */
                   3354:       /*       } */
                   3355:       /* } */
1.126     brouard  3356:       savm=oldm;
                   3357:       oldm=newm;
                   3358:     }
                   3359:     for(i=1; i<=nlstate+ndeath; i++)
                   3360:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3361:        po[i][j][h]=newm[i][j];
                   3362:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3363:       }
1.128     brouard  3364:     /*printf("h=%d ",h);*/
1.126     brouard  3365:   } /* end h */
1.267     brouard  3366:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3367:   return po;
                   3368: }
                   3369: 
1.217     brouard  3370: /************* Higher Back Matrix Product ***************/
1.218     brouard  3371: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3372: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3373: {
1.266     brouard  3374:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3375:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3376:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3377:      nhstepm*hstepm matrices.
                   3378:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3379:      (typically every 2 years instead of every month which is too big
1.217     brouard  3380:      for the memory).
1.218     brouard  3381:      Model is determined by parameters x and covariates have to be
1.266     brouard  3382:      included manually here. Then we use a call to bmij(x and cov)
                   3383:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3384:   */
1.217     brouard  3385: 
                   3386:   int i, j, d, h, k;
1.266     brouard  3387:   double **out, cov[NCOVMAX+1], **bmij();
                   3388:   double **newm, ***newmm;
1.217     brouard  3389:   double agexact;
                   3390:   double agebegin, ageend;
1.222     brouard  3391:   double **oldm, **savm;
1.217     brouard  3392: 
1.266     brouard  3393:   newmm=po; /* To be saved */
                   3394:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3395:   /* Hstepm could be zero and should return the unit matrix */
                   3396:   for (i=1;i<=nlstate+ndeath;i++)
                   3397:     for (j=1;j<=nlstate+ndeath;j++){
                   3398:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3399:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3400:     }
                   3401:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3402:   for(h=1; h <=nhstepm; h++){
                   3403:     for(d=1; d <=hstepm; d++){
                   3404:       newm=savm;
                   3405:       /* Covariates have to be included here again */
                   3406:       cov[1]=1.;
1.271     brouard  3407:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3408:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3409:       cov[2]=agexact;
                   3410:       if(nagesqr==1)
1.222     brouard  3411:        cov[3]= agexact*agexact;
1.266     brouard  3412:       for (k=1; k<=cptcovn;k++){
                   3413:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3414:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3415:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3416:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3417:       }
1.267     brouard  3418:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3419:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3420:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3421:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3422:       }
                   3423:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3424:        if(Dummy[Tvar[Tage[k]]]){
                   3425:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3426:        } else{
                   3427:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3428:        }
                   3429:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3430:       }
                   3431:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3432:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3433:       }                        
1.217     brouard  3434:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3435:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3436: 
1.218     brouard  3437:       /* Careful transposed matrix */
1.266     brouard  3438:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3439:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3440:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3441:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3442:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3443:       /* if((int)age == 70){ */
                   3444:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3445:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3446:       /*         printf("%d pmmij ",i); */
                   3447:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3448:       /*           printf("%f ",pmmij[i][j]); */
                   3449:       /*         } */
                   3450:       /*         printf(" oldm "); */
                   3451:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3452:       /*           printf("%f ",oldm[i][j]); */
                   3453:       /*         } */
                   3454:       /*         printf("\n"); */
                   3455:       /*       } */
                   3456:       /* } */
                   3457:       savm=oldm;
                   3458:       oldm=newm;
                   3459:     }
                   3460:     for(i=1; i<=nlstate+ndeath; i++)
                   3461:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3462:        po[i][j][h]=newm[i][j];
1.268     brouard  3463:        /* if(h==nhstepm) */
                   3464:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3465:       }
1.268     brouard  3466:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3467:   } /* end h */
1.268     brouard  3468:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3469:   return po;
                   3470: }
                   3471: 
                   3472: 
1.162     brouard  3473: #ifdef NLOPT
                   3474:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3475:   double fret;
                   3476:   double *xt;
                   3477:   int j;
                   3478:   myfunc_data *d2 = (myfunc_data *) pd;
                   3479: /* xt = (p1-1); */
                   3480:   xt=vector(1,n); 
                   3481:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3482: 
                   3483:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3484:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3485:   printf("Function = %.12lf ",fret);
                   3486:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3487:   printf("\n");
                   3488:  free_vector(xt,1,n);
                   3489:   return fret;
                   3490: }
                   3491: #endif
1.126     brouard  3492: 
                   3493: /*************** log-likelihood *************/
                   3494: double func( double *x)
                   3495: {
1.226     brouard  3496:   int i, ii, j, k, mi, d, kk;
                   3497:   int ioffset=0;
                   3498:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3499:   double **out;
                   3500:   double lli; /* Individual log likelihood */
                   3501:   int s1, s2;
1.228     brouard  3502:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3503:   double bbh, survp;
                   3504:   long ipmx;
                   3505:   double agexact;
                   3506:   /*extern weight */
                   3507:   /* We are differentiating ll according to initial status */
                   3508:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3509:   /*for(i=1;i<imx;i++) 
                   3510:     printf(" %d\n",s[4][i]);
                   3511:   */
1.162     brouard  3512: 
1.226     brouard  3513:   ++countcallfunc;
1.162     brouard  3514: 
1.226     brouard  3515:   cov[1]=1.;
1.126     brouard  3516: 
1.226     brouard  3517:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3518:   ioffset=0;
1.226     brouard  3519:   if(mle==1){
                   3520:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3521:       /* Computes the values of the ncovmodel covariates of the model
                   3522:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3523:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3524:         to be observed in j being in i according to the model.
                   3525:       */
1.243     brouard  3526:       ioffset=2+nagesqr ;
1.233     brouard  3527:    /* Fixed */
1.234     brouard  3528:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3529:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3530:       }
1.226     brouard  3531:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3532:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3533:         has been calculated etc */
                   3534:       /* For an individual i, wav[i] gives the number of effective waves */
                   3535:       /* We compute the contribution to Likelihood of each effective transition
                   3536:         mw[mi][i] is real wave of the mi th effectve wave */
                   3537:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3538:         s2=s[mw[mi+1][i]][i];
                   3539:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3540:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3541:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3542:       */
                   3543:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3544:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3545:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3546:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3547:        }
                   3548:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3549:          for (j=1;j<=nlstate+ndeath;j++){
                   3550:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3551:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3552:          }
                   3553:        for(d=0; d<dh[mi][i]; d++){
                   3554:          newm=savm;
                   3555:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3556:          cov[2]=agexact;
                   3557:          if(nagesqr==1)
                   3558:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3559:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3560:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3561:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3562:          else
                   3563:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3564:          }
                   3565:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3566:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3567:          savm=oldm;
                   3568:          oldm=newm;
                   3569:        } /* end mult */
                   3570:        
                   3571:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3572:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3573:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3574:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3575:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3576:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3577:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3578:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3579:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3580:                                 * -stepm/2 to stepm/2 .
                   3581:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3582:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3583:                                 */
1.234     brouard  3584:        s1=s[mw[mi][i]][i];
                   3585:        s2=s[mw[mi+1][i]][i];
                   3586:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3587:        /* bias bh is positive if real duration
                   3588:         * is higher than the multiple of stepm and negative otherwise.
                   3589:         */
                   3590:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3591:        if( s2 > nlstate){ 
                   3592:          /* i.e. if s2 is a death state and if the date of death is known 
                   3593:             then the contribution to the likelihood is the probability to 
                   3594:             die between last step unit time and current  step unit time, 
                   3595:             which is also equal to probability to die before dh 
                   3596:             minus probability to die before dh-stepm . 
                   3597:             In version up to 0.92 likelihood was computed
                   3598:             as if date of death was unknown. Death was treated as any other
                   3599:             health state: the date of the interview describes the actual state
                   3600:             and not the date of a change in health state. The former idea was
                   3601:             to consider that at each interview the state was recorded
                   3602:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3603:             introduced the exact date of death then we should have modified
                   3604:             the contribution of an exact death to the likelihood. This new
                   3605:             contribution is smaller and very dependent of the step unit
                   3606:             stepm. It is no more the probability to die between last interview
                   3607:             and month of death but the probability to survive from last
                   3608:             interview up to one month before death multiplied by the
                   3609:             probability to die within a month. Thanks to Chris
                   3610:             Jackson for correcting this bug.  Former versions increased
                   3611:             mortality artificially. The bad side is that we add another loop
                   3612:             which slows down the processing. The difference can be up to 10%
                   3613:             lower mortality.
                   3614:          */
                   3615:          /* If, at the beginning of the maximization mostly, the
                   3616:             cumulative probability or probability to be dead is
                   3617:             constant (ie = 1) over time d, the difference is equal to
                   3618:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3619:             s1 at precedent wave, to be dead a month before current
                   3620:             wave is equal to probability, being at state s1 at
                   3621:             precedent wave, to be dead at mont of the current
                   3622:             wave. Then the observed probability (that this person died)
                   3623:             is null according to current estimated parameter. In fact,
                   3624:             it should be very low but not zero otherwise the log go to
                   3625:             infinity.
                   3626:          */
1.183     brouard  3627: /* #ifdef INFINITYORIGINAL */
                   3628: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3629: /* #else */
                   3630: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3631: /*         lli=log(mytinydouble); */
                   3632: /*       else */
                   3633: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3634: /* #endif */
1.226     brouard  3635:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3636:          
1.226     brouard  3637:        } else if  ( s2==-1 ) { /* alive */
                   3638:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3639:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3640:          /*survp += out[s1][j]; */
                   3641:          lli= log(survp);
                   3642:        }
                   3643:        else if  (s2==-4) { 
                   3644:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3645:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3646:          lli= log(survp); 
                   3647:        } 
                   3648:        else if  (s2==-5) { 
                   3649:          for (j=1,survp=0. ; j<=2; j++)  
                   3650:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3651:          lli= log(survp); 
                   3652:        } 
                   3653:        else{
                   3654:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3655:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3656:        } 
                   3657:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3658:        /*if(lli ==000.0)*/
                   3659:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3660:        ipmx +=1;
                   3661:        sw += weight[i];
                   3662:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3663:        /* if (lli < log(mytinydouble)){ */
                   3664:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3665:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3666:        /* } */
                   3667:       } /* end of wave */
                   3668:     } /* end of individual */
                   3669:   }  else if(mle==2){
                   3670:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3671:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3672:       for(mi=1; mi<= wav[i]-1; mi++){
                   3673:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3674:          for (j=1;j<=nlstate+ndeath;j++){
                   3675:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3676:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3677:          }
                   3678:        for(d=0; d<=dh[mi][i]; d++){
                   3679:          newm=savm;
                   3680:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3681:          cov[2]=agexact;
                   3682:          if(nagesqr==1)
                   3683:            cov[3]= agexact*agexact;
                   3684:          for (kk=1; kk<=cptcovage;kk++) {
                   3685:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3686:          }
                   3687:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3688:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3689:          savm=oldm;
                   3690:          oldm=newm;
                   3691:        } /* end mult */
                   3692:       
                   3693:        s1=s[mw[mi][i]][i];
                   3694:        s2=s[mw[mi+1][i]][i];
                   3695:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3696:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3697:        ipmx +=1;
                   3698:        sw += weight[i];
                   3699:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3700:       } /* end of wave */
                   3701:     } /* end of individual */
                   3702:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3703:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3704:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3705:       for(mi=1; mi<= wav[i]-1; mi++){
                   3706:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3707:          for (j=1;j<=nlstate+ndeath;j++){
                   3708:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3709:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3710:          }
                   3711:        for(d=0; d<dh[mi][i]; d++){
                   3712:          newm=savm;
                   3713:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3714:          cov[2]=agexact;
                   3715:          if(nagesqr==1)
                   3716:            cov[3]= agexact*agexact;
                   3717:          for (kk=1; kk<=cptcovage;kk++) {
                   3718:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3719:          }
                   3720:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3721:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3722:          savm=oldm;
                   3723:          oldm=newm;
                   3724:        } /* end mult */
                   3725:       
                   3726:        s1=s[mw[mi][i]][i];
                   3727:        s2=s[mw[mi+1][i]][i];
                   3728:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3729:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3730:        ipmx +=1;
                   3731:        sw += weight[i];
                   3732:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3733:       } /* end of wave */
                   3734:     } /* end of individual */
                   3735:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3736:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3737:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3738:       for(mi=1; mi<= wav[i]-1; mi++){
                   3739:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3740:          for (j=1;j<=nlstate+ndeath;j++){
                   3741:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3742:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3743:          }
                   3744:        for(d=0; d<dh[mi][i]; d++){
                   3745:          newm=savm;
                   3746:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3747:          cov[2]=agexact;
                   3748:          if(nagesqr==1)
                   3749:            cov[3]= agexact*agexact;
                   3750:          for (kk=1; kk<=cptcovage;kk++) {
                   3751:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3752:          }
1.126     brouard  3753:        
1.226     brouard  3754:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3755:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3756:          savm=oldm;
                   3757:          oldm=newm;
                   3758:        } /* end mult */
                   3759:       
                   3760:        s1=s[mw[mi][i]][i];
                   3761:        s2=s[mw[mi+1][i]][i];
                   3762:        if( s2 > nlstate){ 
                   3763:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3764:        } else if  ( s2==-1 ) { /* alive */
                   3765:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3766:            survp += out[s1][j];
                   3767:          lli= log(survp);
                   3768:        }else{
                   3769:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3770:        }
                   3771:        ipmx +=1;
                   3772:        sw += weight[i];
                   3773:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3774: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3775:       } /* end of wave */
                   3776:     } /* end of individual */
                   3777:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3778:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3779:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3780:       for(mi=1; mi<= wav[i]-1; mi++){
                   3781:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3782:          for (j=1;j<=nlstate+ndeath;j++){
                   3783:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3784:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3785:          }
                   3786:        for(d=0; d<dh[mi][i]; d++){
                   3787:          newm=savm;
                   3788:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3789:          cov[2]=agexact;
                   3790:          if(nagesqr==1)
                   3791:            cov[3]= agexact*agexact;
                   3792:          for (kk=1; kk<=cptcovage;kk++) {
                   3793:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3794:          }
1.126     brouard  3795:        
1.226     brouard  3796:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3797:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3798:          savm=oldm;
                   3799:          oldm=newm;
                   3800:        } /* end mult */
                   3801:       
                   3802:        s1=s[mw[mi][i]][i];
                   3803:        s2=s[mw[mi+1][i]][i];
                   3804:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3805:        ipmx +=1;
                   3806:        sw += weight[i];
                   3807:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3808:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3809:       } /* end of wave */
                   3810:     } /* end of individual */
                   3811:   } /* End of if */
                   3812:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3813:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3814:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3815:   return -l;
1.126     brouard  3816: }
                   3817: 
                   3818: /*************** log-likelihood *************/
                   3819: double funcone( double *x)
                   3820: {
1.228     brouard  3821:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3822:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3823:   int ioffset=0;
1.131     brouard  3824:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3825:   double **out;
                   3826:   double lli; /* Individual log likelihood */
                   3827:   double llt;
                   3828:   int s1, s2;
1.228     brouard  3829:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3830: 
1.126     brouard  3831:   double bbh, survp;
1.187     brouard  3832:   double agexact;
1.214     brouard  3833:   double agebegin, ageend;
1.126     brouard  3834:   /*extern weight */
                   3835:   /* We are differentiating ll according to initial status */
                   3836:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3837:   /*for(i=1;i<imx;i++) 
                   3838:     printf(" %d\n",s[4][i]);
                   3839:   */
                   3840:   cov[1]=1.;
                   3841: 
                   3842:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3843:   ioffset=0;
                   3844:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3845:     /* ioffset=2+nagesqr+cptcovage; */
                   3846:     ioffset=2+nagesqr;
1.232     brouard  3847:     /* Fixed */
1.224     brouard  3848:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3849:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
1.311   ! brouard  3850:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products *//* Missing values are set to -1 but should be dropped */
1.232     brouard  3851:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3852: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3853: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3854: /*    cov[2+6]=covar[2][i]; V2  */
                   3855: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3856: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3857: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3858: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3859: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3860: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3861:     }
1.232     brouard  3862:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3863:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3864:     /* } */
1.231     brouard  3865:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3866:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3867:     /* } */
1.225     brouard  3868:     
1.233     brouard  3869: 
                   3870:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3871:     /* Wave varying (but not age varying) */
                   3872:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3873:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3874:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3875:       }
1.232     brouard  3876:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3877:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3878:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3879:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3880:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3881:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3882:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3883:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3884:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3885:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3886:       /* } */
1.126     brouard  3887:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3888:        for (j=1;j<=nlstate+ndeath;j++){
                   3889:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3890:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3891:        }
1.214     brouard  3892:       
                   3893:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3894:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3895:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3896:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3897:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3898:          and mw[mi+1][i]. dh depends on stepm.*/
                   3899:        newm=savm;
1.247     brouard  3900:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3901:        cov[2]=agexact;
                   3902:        if(nagesqr==1)
                   3903:          cov[3]= agexact*agexact;
                   3904:        for (kk=1; kk<=cptcovage;kk++) {
                   3905:          if(!FixedV[Tvar[Tage[kk]]])
                   3906:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3907:          else
                   3908:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3909:        }
                   3910:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3911:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3912:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3913:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3914:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3915:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3916:        savm=oldm;
                   3917:        oldm=newm;
1.126     brouard  3918:       } /* end mult */
                   3919:       
                   3920:       s1=s[mw[mi][i]][i];
                   3921:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3922:       /* if(s2==-1){ */
1.268     brouard  3923:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3924:       /*       /\* exit(1); *\/ */
                   3925:       /* } */
1.126     brouard  3926:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3927:       /* bias is positive if real duration
                   3928:        * is higher than the multiple of stepm and negative otherwise.
                   3929:        */
                   3930:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3931:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3932:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3933:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3934:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3935:        lli= log(survp);
1.126     brouard  3936:       }else if (mle==1){
1.242     brouard  3937:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3938:       } else if(mle==2){
1.242     brouard  3939:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3940:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3941:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3942:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3943:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3944:       } else{  /* mle=0 back to 1 */
1.242     brouard  3945:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3946:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3947:       } /* End of if */
                   3948:       ipmx +=1;
                   3949:       sw += weight[i];
                   3950:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3951:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3952:       if(globpr){
1.246     brouard  3953:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3954:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3955:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3956:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3957:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3958:          llt +=ll[k]*gipmx/gsw;
                   3959:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3960:        }
                   3961:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3962:       }
1.232     brouard  3963:        } /* end of wave */
                   3964: } /* end of individual */
                   3965: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3966: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3967: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3968: if(globpr==0){ /* First time we count the contributions and weights */
                   3969:        gipmx=ipmx;
                   3970:        gsw=sw;
                   3971: }
                   3972: return -l;
1.126     brouard  3973: }
                   3974: 
                   3975: 
                   3976: /*************** function likelione ***********/
1.292     brouard  3977: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  3978: {
                   3979:   /* This routine should help understanding what is done with 
                   3980:      the selection of individuals/waves and
                   3981:      to check the exact contribution to the likelihood.
                   3982:      Plotting could be done.
                   3983:    */
                   3984:   int k;
                   3985: 
                   3986:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  3987:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  3988:     strcat(fileresilk,fileresu);
1.126     brouard  3989:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   3990:       printf("Problem with resultfile: %s\n", fileresilk);
                   3991:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   3992:     }
1.214     brouard  3993:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   3994:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  3995:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   3996:     for(k=1; k<=nlstate; k++) 
                   3997:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   3998:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   3999:   }
                   4000: 
1.292     brouard  4001:   *fretone=(*func)(p);
1.126     brouard  4002:   if(*globpri !=0){
                   4003:     fclose(ficresilk);
1.205     brouard  4004:     if (mle ==0)
                   4005:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   4006:     else if(mle >=1)
                   4007:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   4008:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  4009:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  4010:       
                   4011:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  4012:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  4013: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   4014:     }
1.207     brouard  4015:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  4016: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4017:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  4018: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4019:     fflush(fichtm);
1.205     brouard  4020:   }
1.126     brouard  4021:   return;
                   4022: }
                   4023: 
                   4024: 
                   4025: /*********** Maximum Likelihood Estimation ***************/
                   4026: 
                   4027: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   4028: {
1.165     brouard  4029:   int i,j, iter=0;
1.126     brouard  4030:   double **xi;
                   4031:   double fret;
                   4032:   double fretone; /* Only one call to likelihood */
                   4033:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  4034: 
                   4035: #ifdef NLOPT
                   4036:   int creturn;
                   4037:   nlopt_opt opt;
                   4038:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   4039:   double *lb;
                   4040:   double minf; /* the minimum objective value, upon return */
                   4041:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   4042:   myfunc_data dinst, *d = &dinst;
                   4043: #endif
                   4044: 
                   4045: 
1.126     brouard  4046:   xi=matrix(1,npar,1,npar);
                   4047:   for (i=1;i<=npar;i++)
                   4048:     for (j=1;j<=npar;j++)
                   4049:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   4050:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  4051:   strcpy(filerespow,"POW_"); 
1.126     brouard  4052:   strcat(filerespow,fileres);
                   4053:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   4054:     printf("Problem with resultfile: %s\n", filerespow);
                   4055:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   4056:   }
                   4057:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   4058:   for (i=1;i<=nlstate;i++)
                   4059:     for(j=1;j<=nlstate+ndeath;j++)
                   4060:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   4061:   fprintf(ficrespow,"\n");
1.162     brouard  4062: #ifdef POWELL
1.126     brouard  4063:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  4064: #endif
1.126     brouard  4065: 
1.162     brouard  4066: #ifdef NLOPT
                   4067: #ifdef NEWUOA
                   4068:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   4069: #else
                   4070:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   4071: #endif
                   4072:   lb=vector(0,npar-1);
                   4073:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   4074:   nlopt_set_lower_bounds(opt, lb);
                   4075:   nlopt_set_initial_step1(opt, 0.1);
                   4076:   
                   4077:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   4078:   d->function = func;
                   4079:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   4080:   nlopt_set_min_objective(opt, myfunc, d);
                   4081:   nlopt_set_xtol_rel(opt, ftol);
                   4082:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4083:     printf("nlopt failed! %d\n",creturn); 
                   4084:   }
                   4085:   else {
                   4086:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4087:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4088:     iter=1; /* not equal */
                   4089:   }
                   4090:   nlopt_destroy(opt);
                   4091: #endif
1.126     brouard  4092:   free_matrix(xi,1,npar,1,npar);
                   4093:   fclose(ficrespow);
1.203     brouard  4094:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4095:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4096:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4097: 
                   4098: }
                   4099: 
                   4100: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4101: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4102: {
                   4103:   double  **a,**y,*x,pd;
1.203     brouard  4104:   /* double **hess; */
1.164     brouard  4105:   int i, j;
1.126     brouard  4106:   int *indx;
                   4107: 
                   4108:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4109:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4110:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4111:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4112:   double gompertz(double p[]);
1.203     brouard  4113:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4114: 
                   4115:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4116:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4117:   for (i=1;i<=npar;i++){
1.203     brouard  4118:     printf("%d-",i);fflush(stdout);
                   4119:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4120:    
                   4121:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4122:     
                   4123:     /*  printf(" %f ",p[i]);
                   4124:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4125:   }
                   4126:   
                   4127:   for (i=1;i<=npar;i++) {
                   4128:     for (j=1;j<=npar;j++)  {
                   4129:       if (j>i) { 
1.203     brouard  4130:        printf(".%d-%d",i,j);fflush(stdout);
                   4131:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4132:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4133:        
                   4134:        hess[j][i]=hess[i][j];    
                   4135:        /*printf(" %lf ",hess[i][j]);*/
                   4136:       }
                   4137:     }
                   4138:   }
                   4139:   printf("\n");
                   4140:   fprintf(ficlog,"\n");
                   4141: 
                   4142:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4143:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4144:   
                   4145:   a=matrix(1,npar,1,npar);
                   4146:   y=matrix(1,npar,1,npar);
                   4147:   x=vector(1,npar);
                   4148:   indx=ivector(1,npar);
                   4149:   for (i=1;i<=npar;i++)
                   4150:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4151:   ludcmp(a,npar,indx,&pd);
                   4152: 
                   4153:   for (j=1;j<=npar;j++) {
                   4154:     for (i=1;i<=npar;i++) x[i]=0;
                   4155:     x[j]=1;
                   4156:     lubksb(a,npar,indx,x);
                   4157:     for (i=1;i<=npar;i++){ 
                   4158:       matcov[i][j]=x[i];
                   4159:     }
                   4160:   }
                   4161: 
                   4162:   printf("\n#Hessian matrix#\n");
                   4163:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4164:   for (i=1;i<=npar;i++) { 
                   4165:     for (j=1;j<=npar;j++) { 
1.203     brouard  4166:       printf("%.6e ",hess[i][j]);
                   4167:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4168:     }
                   4169:     printf("\n");
                   4170:     fprintf(ficlog,"\n");
                   4171:   }
                   4172: 
1.203     brouard  4173:   /* printf("\n#Covariance matrix#\n"); */
                   4174:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4175:   /* for (i=1;i<=npar;i++) {  */
                   4176:   /*   for (j=1;j<=npar;j++) {  */
                   4177:   /*     printf("%.6e ",matcov[i][j]); */
                   4178:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4179:   /*   } */
                   4180:   /*   printf("\n"); */
                   4181:   /*   fprintf(ficlog,"\n"); */
                   4182:   /* } */
                   4183: 
1.126     brouard  4184:   /* Recompute Inverse */
1.203     brouard  4185:   /* for (i=1;i<=npar;i++) */
                   4186:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4187:   /* ludcmp(a,npar,indx,&pd); */
                   4188: 
                   4189:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4190: 
                   4191:   /* for (j=1;j<=npar;j++) { */
                   4192:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4193:   /*   x[j]=1; */
                   4194:   /*   lubksb(a,npar,indx,x); */
                   4195:   /*   for (i=1;i<=npar;i++){  */
                   4196:   /*     y[i][j]=x[i]; */
                   4197:   /*     printf("%.3e ",y[i][j]); */
                   4198:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4199:   /*   } */
                   4200:   /*   printf("\n"); */
                   4201:   /*   fprintf(ficlog,"\n"); */
                   4202:   /* } */
                   4203: 
                   4204:   /* Verifying the inverse matrix */
                   4205: #ifdef DEBUGHESS
                   4206:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4207: 
1.203     brouard  4208:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4209:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4210: 
                   4211:   for (j=1;j<=npar;j++) {
                   4212:     for (i=1;i<=npar;i++){ 
1.203     brouard  4213:       printf("%.2f ",y[i][j]);
                   4214:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4215:     }
                   4216:     printf("\n");
                   4217:     fprintf(ficlog,"\n");
                   4218:   }
1.203     brouard  4219: #endif
1.126     brouard  4220: 
                   4221:   free_matrix(a,1,npar,1,npar);
                   4222:   free_matrix(y,1,npar,1,npar);
                   4223:   free_vector(x,1,npar);
                   4224:   free_ivector(indx,1,npar);
1.203     brouard  4225:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4226: 
                   4227: 
                   4228: }
                   4229: 
                   4230: /*************** hessian matrix ****************/
                   4231: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4232: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4233:   int i;
                   4234:   int l=1, lmax=20;
1.203     brouard  4235:   double k1,k2, res, fx;
1.132     brouard  4236:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4237:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4238:   int k=0,kmax=10;
                   4239:   double l1;
                   4240: 
                   4241:   fx=func(x);
                   4242:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4243:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4244:     l1=pow(10,l);
                   4245:     delts=delt;
                   4246:     for(k=1 ; k <kmax; k=k+1){
                   4247:       delt = delta*(l1*k);
                   4248:       p2[theta]=x[theta] +delt;
1.145     brouard  4249:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4250:       p2[theta]=x[theta]-delt;
                   4251:       k2=func(p2)-fx;
                   4252:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4253:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4254:       
1.203     brouard  4255: #ifdef DEBUGHESSII
1.126     brouard  4256:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4257:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4258: #endif
                   4259:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4260:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4261:        k=kmax;
                   4262:       }
                   4263:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4264:        k=kmax; l=lmax*10;
1.126     brouard  4265:       }
                   4266:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4267:        delts=delt;
                   4268:       }
1.203     brouard  4269:     } /* End loop k */
1.126     brouard  4270:   }
                   4271:   delti[theta]=delts;
                   4272:   return res; 
                   4273:   
                   4274: }
                   4275: 
1.203     brouard  4276: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4277: {
                   4278:   int i;
1.164     brouard  4279:   int l=1, lmax=20;
1.126     brouard  4280:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4281:   double p2[MAXPARM+1];
1.203     brouard  4282:   int k, kmax=1;
                   4283:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4284: 
                   4285:   int firstime=0;
1.203     brouard  4286:   
1.126     brouard  4287:   fx=func(x);
1.203     brouard  4288:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4289:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4290:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4291:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4292:     k1=func(p2)-fx;
                   4293:   
1.203     brouard  4294:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4295:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4296:     k2=func(p2)-fx;
                   4297:   
1.203     brouard  4298:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4299:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4300:     k3=func(p2)-fx;
                   4301:   
1.203     brouard  4302:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4303:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4304:     k4=func(p2)-fx;
1.203     brouard  4305:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4306:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4307:       firstime=1;
1.203     brouard  4308:       kmax=kmax+10;
1.208     brouard  4309:     }
                   4310:     if(kmax >=10 || firstime ==1){
1.246     brouard  4311:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4312:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4313:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4314:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4315:     }
                   4316: #ifdef DEBUGHESSIJ
                   4317:     v1=hess[thetai][thetai];
                   4318:     v2=hess[thetaj][thetaj];
                   4319:     cv12=res;
                   4320:     /* Computing eigen value of Hessian matrix */
                   4321:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4322:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4323:     if ((lc2 <0) || (lc1 <0) ){
                   4324:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4325:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4326:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4327:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4328:     }
1.126     brouard  4329: #endif
                   4330:   }
                   4331:   return res;
                   4332: }
                   4333: 
1.203     brouard  4334:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4335: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4336: /* { */
                   4337: /*   int i; */
                   4338: /*   int l=1, lmax=20; */
                   4339: /*   double k1,k2,k3,k4,res,fx; */
                   4340: /*   double p2[MAXPARM+1]; */
                   4341: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4342: /*   int k=0,kmax=10; */
                   4343: /*   double l1; */
                   4344:   
                   4345: /*   fx=func(x); */
                   4346: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4347: /*     l1=pow(10,l); */
                   4348: /*     delts=delt; */
                   4349: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4350: /*       delt = delti*(l1*k); */
                   4351: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4352: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4353: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4354: /*       k1=func(p2)-fx; */
                   4355:       
                   4356: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4357: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4358: /*       k2=func(p2)-fx; */
                   4359:       
                   4360: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4361: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4362: /*       k3=func(p2)-fx; */
                   4363:       
                   4364: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4365: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4366: /*       k4=func(p2)-fx; */
                   4367: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4368: /* #ifdef DEBUGHESSIJ */
                   4369: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4370: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4371: /* #endif */
                   4372: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4373: /*     k=kmax; */
                   4374: /*       } */
                   4375: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4376: /*     k=kmax; l=lmax*10; */
                   4377: /*       } */
                   4378: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4379: /*     delts=delt; */
                   4380: /*       } */
                   4381: /*     } /\* End loop k *\/ */
                   4382: /*   } */
                   4383: /*   delti[theta]=delts; */
                   4384: /*   return res;  */
                   4385: /* } */
                   4386: 
                   4387: 
1.126     brouard  4388: /************** Inverse of matrix **************/
                   4389: void ludcmp(double **a, int n, int *indx, double *d) 
                   4390: { 
                   4391:   int i,imax,j,k; 
                   4392:   double big,dum,sum,temp; 
                   4393:   double *vv; 
                   4394:  
                   4395:   vv=vector(1,n); 
                   4396:   *d=1.0; 
                   4397:   for (i=1;i<=n;i++) { 
                   4398:     big=0.0; 
                   4399:     for (j=1;j<=n;j++) 
                   4400:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4401:     if (big == 0.0){
                   4402:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4403:       for (j=1;j<=n;j++) {
                   4404:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4405:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4406:       }
                   4407:       fflush(ficlog);
                   4408:       fclose(ficlog);
                   4409:       nrerror("Singular matrix in routine ludcmp"); 
                   4410:     }
1.126     brouard  4411:     vv[i]=1.0/big; 
                   4412:   } 
                   4413:   for (j=1;j<=n;j++) { 
                   4414:     for (i=1;i<j;i++) { 
                   4415:       sum=a[i][j]; 
                   4416:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4417:       a[i][j]=sum; 
                   4418:     } 
                   4419:     big=0.0; 
                   4420:     for (i=j;i<=n;i++) { 
                   4421:       sum=a[i][j]; 
                   4422:       for (k=1;k<j;k++) 
                   4423:        sum -= a[i][k]*a[k][j]; 
                   4424:       a[i][j]=sum; 
                   4425:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4426:        big=dum; 
                   4427:        imax=i; 
                   4428:       } 
                   4429:     } 
                   4430:     if (j != imax) { 
                   4431:       for (k=1;k<=n;k++) { 
                   4432:        dum=a[imax][k]; 
                   4433:        a[imax][k]=a[j][k]; 
                   4434:        a[j][k]=dum; 
                   4435:       } 
                   4436:       *d = -(*d); 
                   4437:       vv[imax]=vv[j]; 
                   4438:     } 
                   4439:     indx[j]=imax; 
                   4440:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4441:     if (j != n) { 
                   4442:       dum=1.0/(a[j][j]); 
                   4443:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4444:     } 
                   4445:   } 
                   4446:   free_vector(vv,1,n);  /* Doesn't work */
                   4447: ;
                   4448: } 
                   4449: 
                   4450: void lubksb(double **a, int n, int *indx, double b[]) 
                   4451: { 
                   4452:   int i,ii=0,ip,j; 
                   4453:   double sum; 
                   4454:  
                   4455:   for (i=1;i<=n;i++) { 
                   4456:     ip=indx[i]; 
                   4457:     sum=b[ip]; 
                   4458:     b[ip]=b[i]; 
                   4459:     if (ii) 
                   4460:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4461:     else if (sum) ii=i; 
                   4462:     b[i]=sum; 
                   4463:   } 
                   4464:   for (i=n;i>=1;i--) { 
                   4465:     sum=b[i]; 
                   4466:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4467:     b[i]=sum/a[i][i]; 
                   4468:   } 
                   4469: } 
                   4470: 
                   4471: void pstamp(FILE *fichier)
                   4472: {
1.196     brouard  4473:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4474: }
                   4475: 
1.297     brouard  4476: void date2dmy(double date,double *day, double *month, double *year){
                   4477:   double yp=0., yp1=0., yp2=0.;
                   4478:   
                   4479:   yp1=modf(date,&yp);/* extracts integral of date in yp  and
                   4480:                        fractional in yp1 */
                   4481:   *year=yp;
                   4482:   yp2=modf((yp1*12),&yp);
                   4483:   *month=yp;
                   4484:   yp1=modf((yp2*30.5),&yp);
                   4485:   *day=yp;
                   4486:   if(*day==0) *day=1;
                   4487:   if(*month==0) *month=1;
                   4488: }
                   4489: 
1.253     brouard  4490: 
                   4491: 
1.126     brouard  4492: /************ Frequencies ********************/
1.251     brouard  4493: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4494:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4495:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4496: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4497:   
1.265     brouard  4498:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4499:   int iind=0, iage=0;
                   4500:   int mi; /* Effective wave */
                   4501:   int first;
                   4502:   double ***freq; /* Frequencies */
1.268     brouard  4503:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4504:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4505:   double *meanq, *stdq, *idq;
1.226     brouard  4506:   double **meanqt;
                   4507:   double *pp, **prop, *posprop, *pospropt;
                   4508:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4509:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4510:   double agebegin, ageend;
                   4511:     
                   4512:   pp=vector(1,nlstate);
1.251     brouard  4513:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4514:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4515:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4516:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4517:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4518:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4519:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4520:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4521:   strcpy(fileresp,"P_");
                   4522:   strcat(fileresp,fileresu);
                   4523:   /*strcat(fileresphtm,fileresu);*/
                   4524:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4525:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4526:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4527:     exit(0);
                   4528:   }
1.240     brouard  4529:   
1.226     brouard  4530:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4531:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4532:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4533:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4534:     fflush(ficlog);
                   4535:     exit(70); 
                   4536:   }
                   4537:   else{
                   4538:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4539: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4540: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4541:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4542:   }
1.237     brouard  4543:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4544:   
1.226     brouard  4545:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4546:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4547:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4548:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4549:     fflush(ficlog);
                   4550:     exit(70); 
1.240     brouard  4551:   } else{
1.226     brouard  4552:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4553: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4554: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4555:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4556:   }
1.240     brouard  4557:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4558:   
1.253     brouard  4559:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4560:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4561:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4562:   j1=0;
1.126     brouard  4563:   
1.227     brouard  4564:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4565:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4566:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4567:   
                   4568:   
1.226     brouard  4569:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4570:      reference=low_education V1=0,V2=0
                   4571:      med_educ                V1=1 V2=0, 
                   4572:      high_educ               V1=0 V2=1
                   4573:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4574:   */
1.249     brouard  4575:   dateintsum=0;
                   4576:   k2cpt=0;
                   4577: 
1.253     brouard  4578:   if(cptcoveff == 0 )
1.265     brouard  4579:     nl=1;  /* Constant and age model only */
1.253     brouard  4580:   else
                   4581:     nl=2;
1.265     brouard  4582: 
                   4583:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4584:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4585:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4586:    *     freq[s1][s2][iage] =0.
                   4587:    *     Loop on iind
                   4588:    *       ++freq[s1][s2][iage] weighted
                   4589:    *     end iind
                   4590:    *     if covariate and j!0
                   4591:    *       headers Variable on one line
                   4592:    *     endif cov j!=0
                   4593:    *     header of frequency table by age
                   4594:    *     Loop on age
                   4595:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4596:    *       pos+=freq[s1][s2][iage] weighted
                   4597:    *       Loop on s1 initial state
                   4598:    *         fprintf(ficresp
                   4599:    *       end s1
                   4600:    *     end age
                   4601:    *     if j!=0 computes starting values
                   4602:    *     end compute starting values
                   4603:    *   end j1
                   4604:    * end nl 
                   4605:    */
1.253     brouard  4606:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4607:     if(nj==1)
                   4608:       j=0;  /* First pass for the constant */
1.265     brouard  4609:     else{
1.253     brouard  4610:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4611:     }
1.251     brouard  4612:     first=1;
1.265     brouard  4613:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4614:       posproptt=0.;
                   4615:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4616:        scanf("%d", i);*/
                   4617:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4618:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4619:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4620:            freq[i][s2][m]=0;
1.251     brouard  4621:       
                   4622:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4623:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4624:          prop[i][m]=0;
                   4625:        posprop[i]=0;
                   4626:        pospropt[i]=0;
                   4627:       }
1.283     brouard  4628:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4629:         idq[z1]=0.;
                   4630:         meanq[z1]=0.;
                   4631:         stdq[z1]=0.;
1.283     brouard  4632:       }
                   4633:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4634:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4635:       /*         meanqt[m][z1]=0.; */
                   4636:       /*       } */
                   4637:       /* }       */
1.251     brouard  4638:       /* dateintsum=0; */
                   4639:       /* k2cpt=0; */
                   4640:       
1.265     brouard  4641:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4642:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4643:        bool=1;
                   4644:        if(j !=0){
                   4645:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4646:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4647:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4648:                /* if(Tvaraff[z1] ==-20){ */
                   4649:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4650:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4651:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4652:                /* }else  */
                   4653:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4654:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4655:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4656:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4657:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4658:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4659:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4660:                } /* Onlyf fixed */
                   4661:              } /* end z1 */
                   4662:            } /* cptcovn > 0 */
                   4663:          } /* end any */
                   4664:        }/* end j==0 */
1.265     brouard  4665:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4666:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4667:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4668:            m=mw[mi][iind];
                   4669:            if(j!=0){
                   4670:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4671:                for (z1=1; z1<=cptcoveff; z1++) {
                   4672:                  if( Fixed[Tmodelind[z1]]==1){
                   4673:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4674:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4675:                                                                                      value is -1, we don't select. It differs from the 
                   4676:                                                                                      constant and age model which counts them. */
                   4677:                      bool=0; /* not selected */
                   4678:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4679:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4680:                      bool=0;
                   4681:                    }
                   4682:                  }
                   4683:                }
                   4684:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4685:            } /* end j==0 */
                   4686:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4687:            if(bool==1){ /*Selected */
1.251     brouard  4688:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4689:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4690:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4691:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4692:              if(m >=firstpass && m <=lastpass){
                   4693:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4694:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4695:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4696:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4697:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4698:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4699:                if (m<lastpass) {
                   4700:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4701:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4702:                  if(s[m][iind]==-1)
                   4703:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4704:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.311   ! brouard  4705:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean on known values only */
        !          4706:                    if(!isnan(covar[ncovcol+z1][iind])){
        !          4707:                        idq[z1]=idq[z1]+weight[iind];
        !          4708:                        meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
        !          4709:                        /* stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; *//*error*/
        !          4710:                        stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
        !          4711:                    }
1.284     brouard  4712:                  }
1.251     brouard  4713:                  /* if((int)agev[m][iind] == 55) */
                   4714:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4715:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4716:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4717:                }
1.251     brouard  4718:              } /* end if between passes */  
                   4719:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4720:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4721:                k2cpt++;
                   4722:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4723:              }
1.251     brouard  4724:            }else{
                   4725:              bool=1;
                   4726:            }/* end bool 2 */
                   4727:          } /* end m */
1.284     brouard  4728:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4729:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4730:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4731:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4732:          /* } */
1.251     brouard  4733:        } /* end bool */
                   4734:       } /* end iind = 1 to imx */
                   4735:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4736:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4737:       
                   4738:       
                   4739:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4740:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4741:         pstamp(ficresp);
1.251     brouard  4742:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4743:         pstamp(ficresp);
1.251     brouard  4744:        printf( "\n#********** Variable "); 
                   4745:        fprintf(ficresp, "\n#********** Variable "); 
                   4746:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4747:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4748:        fprintf(ficlog, "\n#********** Variable "); 
                   4749:        for (z1=1; z1<=cptcoveff; z1++){
                   4750:          if(!FixedV[Tvaraff[z1]]){
                   4751:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4752:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4753:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4754:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4755:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4756:          }else{
1.251     brouard  4757:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4758:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4759:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4760:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4761:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4762:          }
                   4763:        }
                   4764:        printf( "**********\n#");
                   4765:        fprintf(ficresp, "**********\n#");
                   4766:        fprintf(ficresphtm, "**********</h3>\n");
                   4767:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4768:        fprintf(ficlog, "**********\n");
                   4769:       }
1.284     brouard  4770:       /*
                   4771:        Printing means of quantitative variables if any
                   4772:       */
                   4773:       for (z1=1; z1<= nqfveff; z1++) {
1.311   ! brouard  4774:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.3g (weighted) individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
        !          4775:        fprintf(ficlog,", mean=%.3g",meanq[z1]/idq[z1]," stdeviation=%.3g\n",stdq[z1]);
1.284     brouard  4776:        if(weightopt==1){
                   4777:          printf(" Weighted mean and standard deviation of");
                   4778:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4779:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4780:        }
1.311   ! brouard  4781:        /* mu = \frac{w x}{\sum w}
        !          4782:            var = \frac{\sum w (x-mu)^2}{\sum w} = \frac{w x^2}{\sum w} - mu^2 
        !          4783:        */
        !          4784:        printf(" fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
        !          4785:        fprintf(ficlog," fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
        !          4786:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.3g (weighted) representatives of the population : %8.5g (%8.5g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
1.284     brouard  4787:       }
                   4788:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4789:       /*       for(m=1;m<=lastpass;m++){ */
                   4790:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4791:       /*   } */
                   4792:       /* } */
1.283     brouard  4793: 
1.251     brouard  4794:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4795:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4796:         fprintf(ficresp, " Age");
                   4797:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4798:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4799:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4800:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4801:       }
1.265     brouard  4802:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4803:       fprintf(ficresphtm, "\n");
                   4804:       
                   4805:       /* Header of frequency table by age */
                   4806:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4807:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4808:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4809:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4810:          if(s2!=0 && m!=0)
                   4811:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4812:        }
1.226     brouard  4813:       }
1.251     brouard  4814:       fprintf(ficresphtmfr, "\n");
                   4815:     
                   4816:       /* For each age */
                   4817:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4818:        fprintf(ficresphtm,"<tr>");
                   4819:        if(iage==iagemax+1){
                   4820:          fprintf(ficlog,"1");
                   4821:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4822:        }else if(iage==iagemax+2){
                   4823:          fprintf(ficlog,"0");
                   4824:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4825:        }else if(iage==iagemax+3){
                   4826:          fprintf(ficlog,"Total");
                   4827:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4828:        }else{
1.240     brouard  4829:          if(first==1){
1.251     brouard  4830:            first=0;
                   4831:            printf("See log file for details...\n");
                   4832:          }
                   4833:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4834:          fprintf(ficlog,"Age %d", iage);
                   4835:        }
1.265     brouard  4836:        for(s1=1; s1 <=nlstate ; s1++){
                   4837:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4838:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4839:        }
1.265     brouard  4840:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4841:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4842:            pos += freq[s1][m][iage];
                   4843:          if(pp[s1]>=1.e-10){
1.251     brouard  4844:            if(first==1){
1.265     brouard  4845:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4846:            }
1.265     brouard  4847:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4848:          }else{
                   4849:            if(first==1)
1.265     brouard  4850:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4851:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4852:          }
                   4853:        }
                   4854:       
1.265     brouard  4855:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4856:          /* posprop[s1]=0; */
                   4857:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4858:            pp[s1] += freq[s1][m][iage];
                   4859:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4860:       
                   4861:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4862:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4863:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4864:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4865:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4866:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4867:        }
                   4868:        
                   4869:        /* Writing ficresp */
                   4870:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4871:           if( iage <= iagemax){
                   4872:            fprintf(ficresp," %d",iage);
                   4873:           }
                   4874:         }else if( nj==2){
                   4875:           if( iage <= iagemax){
                   4876:            fprintf(ficresp," %d",iage);
                   4877:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4878:           }
1.240     brouard  4879:        }
1.265     brouard  4880:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4881:          if(pos>=1.e-5){
1.251     brouard  4882:            if(first==1)
1.265     brouard  4883:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4884:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4885:          }else{
                   4886:            if(first==1)
1.265     brouard  4887:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4888:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4889:          }
                   4890:          if( iage <= iagemax){
                   4891:            if(pos>=1.e-5){
1.265     brouard  4892:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4893:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4894:               }else if( nj==2){
                   4895:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4896:               }
                   4897:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4898:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4899:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4900:            } else{
                   4901:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4902:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4903:            }
1.240     brouard  4904:          }
1.265     brouard  4905:          pospropt[s1] +=posprop[s1];
                   4906:        } /* end loop s1 */
1.251     brouard  4907:        /* pospropt=0.; */
1.265     brouard  4908:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4909:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4910:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4911:              if(first==1){
1.265     brouard  4912:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4913:              }
1.265     brouard  4914:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4915:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4916:            }
1.265     brouard  4917:            if(s1!=0 && m!=0)
                   4918:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4919:          }
1.265     brouard  4920:        } /* end loop s1 */
1.251     brouard  4921:        posproptt=0.; 
1.265     brouard  4922:        for(s1=1; s1 <=nlstate; s1++){
                   4923:          posproptt += pospropt[s1];
1.251     brouard  4924:        }
                   4925:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4926:        fprintf(ficresphtm,"</tr>\n");
                   4927:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4928:          if(iage <= iagemax)
                   4929:            fprintf(ficresp,"\n");
1.240     brouard  4930:        }
1.251     brouard  4931:        if(first==1)
                   4932:          printf("Others in log...\n");
                   4933:        fprintf(ficlog,"\n");
                   4934:       } /* end loop age iage */
1.265     brouard  4935:       
1.251     brouard  4936:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4937:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4938:        if(posproptt < 1.e-5){
1.265     brouard  4939:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4940:        }else{
1.265     brouard  4941:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4942:        }
1.226     brouard  4943:       }
1.251     brouard  4944:       fprintf(ficresphtm,"</tr>\n");
                   4945:       fprintf(ficresphtm,"</table>\n");
                   4946:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4947:       if(posproptt < 1.e-5){
1.251     brouard  4948:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4949:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4950:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4951:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4952:        invalidvarcomb[j1]=1;
1.226     brouard  4953:       }else{
1.251     brouard  4954:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4955:        invalidvarcomb[j1]=0;
1.226     brouard  4956:       }
1.251     brouard  4957:       fprintf(ficresphtmfr,"</table>\n");
                   4958:       fprintf(ficlog,"\n");
                   4959:       if(j!=0){
                   4960:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4961:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4962:          for(k=1; k <=(nlstate+ndeath); k++){
                   4963:            if (k != i) {
1.265     brouard  4964:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4965:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4966:                  if(j1==1){ /* All dummy covariates to zero */
                   4967:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4968:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4969:                    printf("%d%d ",i,k);
                   4970:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4971:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4972:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4973:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4974:                  }
1.253     brouard  4975:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4976:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4977:                    x[iage]= (double)iage;
                   4978:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4979:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  4980:                  }
1.268     brouard  4981:                  /* Some are not finite, but linreg will ignore these ages */
                   4982:                  no=0;
1.253     brouard  4983:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  4984:                  pstart[s1]=b;
                   4985:                  pstart[s1-1]=a;
1.252     brouard  4986:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   4987:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   4988:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  4989:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  4990:                  printf("%d%d ",i,k);
                   4991:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4992:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  4993:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   4994:                  ;
                   4995:                }
                   4996:                /* printf("%12.7f )", param[i][jj][k]); */
                   4997:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  4998:                s1++; 
1.251     brouard  4999:              } /* end jj */
                   5000:            } /* end k!= i */
                   5001:          } /* end k */
1.265     brouard  5002:        } /* end i, s1 */
1.251     brouard  5003:       } /* end j !=0 */
                   5004:     } /* end selected combination of covariate j1 */
                   5005:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   5006:       printf("#Freqsummary: Starting values for the constants:\n");
                   5007:       fprintf(ficlog,"\n");
1.265     brouard  5008:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  5009:        for(k=1; k <=(nlstate+ndeath); k++){
                   5010:          if (k != i) {
                   5011:            printf("%d%d ",i,k);
                   5012:            fprintf(ficlog,"%d%d ",i,k);
                   5013:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  5014:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  5015:              if(jj==1){ /* Age has to be done */
1.265     brouard  5016:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   5017:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   5018:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  5019:              }
                   5020:              /* printf("%12.7f )", param[i][jj][k]); */
                   5021:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5022:              s1++; 
1.250     brouard  5023:            }
1.251     brouard  5024:            printf("\n");
                   5025:            fprintf(ficlog,"\n");
1.250     brouard  5026:          }
                   5027:        }
1.284     brouard  5028:       } /* end of state i */
1.251     brouard  5029:       printf("#Freqsummary\n");
                   5030:       fprintf(ficlog,"\n");
1.265     brouard  5031:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   5032:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   5033:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   5034:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5035:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5036:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   5037:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   5038:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  5039:          /* } */
                   5040:        }
1.265     brouard  5041:       } /* end loop s1 */
1.251     brouard  5042:       
                   5043:       printf("\n");
                   5044:       fprintf(ficlog,"\n");
                   5045:     } /* end j=0 */
1.249     brouard  5046:   } /* end j */
1.252     brouard  5047: 
1.253     brouard  5048:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  5049:     for(i=1, jk=1; i <=nlstate; i++){
                   5050:       for(j=1; j <=nlstate+ndeath; j++){
                   5051:        if(j!=i){
                   5052:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   5053:          printf("%1d%1d",i,j);
                   5054:          fprintf(ficparo,"%1d%1d",i,j);
                   5055:          for(k=1; k<=ncovmodel;k++){
                   5056:            /*    printf(" %lf",param[i][j][k]); */
                   5057:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   5058:            p[jk]=pstart[jk];
                   5059:            printf(" %f ",pstart[jk]);
                   5060:            fprintf(ficparo," %f ",pstart[jk]);
                   5061:            jk++;
                   5062:          }
                   5063:          printf("\n");
                   5064:          fprintf(ficparo,"\n");
                   5065:        }
                   5066:       }
                   5067:     }
                   5068:   } /* end mle=-2 */
1.226     brouard  5069:   dateintmean=dateintsum/k2cpt; 
1.296     brouard  5070:   date2dmy(dateintmean,&jintmean,&mintmean,&aintmean);
1.240     brouard  5071:   
1.226     brouard  5072:   fclose(ficresp);
                   5073:   fclose(ficresphtm);
                   5074:   fclose(ficresphtmfr);
1.283     brouard  5075:   free_vector(idq,1,nqfveff);
1.226     brouard  5076:   free_vector(meanq,1,nqfveff);
1.284     brouard  5077:   free_vector(stdq,1,nqfveff);
1.226     brouard  5078:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  5079:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   5080:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  5081:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5082:   free_vector(pospropt,1,nlstate);
                   5083:   free_vector(posprop,1,nlstate);
1.251     brouard  5084:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5085:   free_vector(pp,1,nlstate);
                   5086:   /* End of freqsummary */
                   5087: }
1.126     brouard  5088: 
1.268     brouard  5089: /* Simple linear regression */
                   5090: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   5091: 
                   5092:   /* y=a+bx regression */
                   5093:   double   sumx = 0.0;                        /* sum of x                      */
                   5094:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   5095:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   5096:   double   sumy = 0.0;                        /* sum of y                      */
                   5097:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   5098:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   5099:   double yhat;
                   5100:   
                   5101:   double denom=0;
                   5102:   int i;
                   5103:   int ne=*no;
                   5104:   
                   5105:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5106:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5107:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5108:       continue;
                   5109:     }
                   5110:     ne=ne+1;
                   5111:     sumx  += x[i];       
                   5112:     sumx2 += x[i]*x[i];  
                   5113:     sumxy += x[i] * y[i];
                   5114:     sumy  += y[i];      
                   5115:     sumy2 += y[i]*y[i]; 
                   5116:     denom = (ne * sumx2 - sumx*sumx);
                   5117:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5118:   } 
                   5119:   
                   5120:   denom = (ne * sumx2 - sumx*sumx);
                   5121:   if (denom == 0) {
                   5122:     // vertical, slope m is infinity
                   5123:     *b = INFINITY;
                   5124:     *a = 0;
                   5125:     if (r) *r = 0;
                   5126:     return 1;
                   5127:   }
                   5128:   
                   5129:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5130:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5131:   if (r!=NULL) {
                   5132:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5133:       sqrt((sumx2 - sumx*sumx/ne) *
                   5134:           (sumy2 - sumy*sumy/ne));
                   5135:   }
                   5136:   *no=ne;
                   5137:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5138:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5139:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5140:       continue;
                   5141:     }
                   5142:     ne=ne+1;
                   5143:     yhat = y[i] - *a -*b* x[i];
                   5144:     sume2  += yhat * yhat ;       
                   5145:     
                   5146:     denom = (ne * sumx2 - sumx*sumx);
                   5147:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5148:   } 
                   5149:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5150:   *sa= *sb * sqrt(sumx2/ne);
                   5151:   
                   5152:   return 0; 
                   5153: }
                   5154: 
1.126     brouard  5155: /************ Prevalence ********************/
1.227     brouard  5156: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5157: {  
                   5158:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5159:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5160:      We still use firstpass and lastpass as another selection.
                   5161:   */
1.126     brouard  5162:  
1.227     brouard  5163:   int i, m, jk, j1, bool, z1,j, iv;
                   5164:   int mi; /* Effective wave */
                   5165:   int iage;
                   5166:   double agebegin, ageend;
                   5167: 
                   5168:   double **prop;
                   5169:   double posprop; 
                   5170:   double  y2; /* in fractional years */
                   5171:   int iagemin, iagemax;
                   5172:   int first; /** to stop verbosity which is redirected to log file */
                   5173: 
                   5174:   iagemin= (int) agemin;
                   5175:   iagemax= (int) agemax;
                   5176:   /*pp=vector(1,nlstate);*/
1.251     brouard  5177:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5178:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5179:   j1=0;
1.222     brouard  5180:   
1.227     brouard  5181:   /*j=cptcoveff;*/
                   5182:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5183:   
1.288     brouard  5184:   first=0;
1.227     brouard  5185:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5186:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5187:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5188:        prop[i][iage]=0.0;
                   5189:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5190:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5191:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5192:     
                   5193:     for (i=1; i<=imx; i++) { /* Each individual */
                   5194:       bool=1;
                   5195:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5196:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5197:        m=mw[mi][i];
                   5198:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5199:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5200:        for (z1=1; z1<=cptcoveff; z1++){
                   5201:          if( Fixed[Tmodelind[z1]]==1){
                   5202:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5203:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5204:              bool=0;
                   5205:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5206:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5207:              bool=0;
                   5208:            }
                   5209:        }
                   5210:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5211:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5212:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5213:          if(m >=firstpass && m <=lastpass){
                   5214:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5215:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5216:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5217:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5218:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5219:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5220:                exit(1);
                   5221:              }
                   5222:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5223:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5224:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5225:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5226:              } /* end valid statuses */ 
                   5227:            } /* end selection of dates */
                   5228:          } /* end selection of waves */
                   5229:        } /* end bool */
                   5230:       } /* end wave */
                   5231:     } /* end individual */
                   5232:     for(i=iagemin; i <= iagemax+3; i++){  
                   5233:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5234:        posprop += prop[jk][i]; 
                   5235:       } 
                   5236:       
                   5237:       for(jk=1; jk <=nlstate ; jk++){      
                   5238:        if( i <=  iagemax){ 
                   5239:          if(posprop>=1.e-5){ 
                   5240:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5241:          } else{
1.288     brouard  5242:            if(!first){
                   5243:              first=1;
1.266     brouard  5244:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5245:            }else{
1.288     brouard  5246:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5247:            }
                   5248:          }
                   5249:        } 
                   5250:       }/* end jk */ 
                   5251:     }/* end i */ 
1.222     brouard  5252:      /*} *//* end i1 */
1.227     brouard  5253:   } /* end j1 */
1.222     brouard  5254:   
1.227     brouard  5255:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5256:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5257:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5258: }  /* End of prevalence */
1.126     brouard  5259: 
                   5260: /************* Waves Concatenation ***************/
                   5261: 
                   5262: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5263: {
1.298     brouard  5264:   /* Concatenates waves: wav[i] is the number of effective (useful waves in the sense that a non interview is useless) of individual i.
1.126     brouard  5265:      Death is a valid wave (if date is known).
                   5266:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5267:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
1.298     brouard  5268:      and mw[mi+1][i]. dh depends on stepm. s[m][i] exists for any wave from firstpass to lastpass
1.227     brouard  5269:   */
1.126     brouard  5270: 
1.224     brouard  5271:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5272:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5273:      double sum=0., jmean=0.;*/
1.224     brouard  5274:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5275:   int j, k=0,jk, ju, jl;
                   5276:   double sum=0.;
                   5277:   first=0;
1.214     brouard  5278:   firstwo=0;
1.217     brouard  5279:   firsthree=0;
1.218     brouard  5280:   firstfour=0;
1.164     brouard  5281:   jmin=100000;
1.126     brouard  5282:   jmax=-1;
                   5283:   jmean=0.;
1.224     brouard  5284: 
                   5285: /* Treating live states */
1.214     brouard  5286:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5287:     mi=0;  /* First valid wave */
1.227     brouard  5288:     mli=0; /* Last valid wave */
1.309     brouard  5289:     m=firstpass;  /* Loop on waves */
                   5290:     while(s[m][i] <= nlstate){  /* a live state or unknown state  */
1.227     brouard  5291:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5292:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5293:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
1.309     brouard  5294:        mw[++mi][i]=m; /* Valid wave: incrementing mi and updating mi; mw[mi] is the wave number of mi_th valid transition   */
1.227     brouard  5295:        mli=m;
1.224     brouard  5296:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5297:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5298:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5299:       }
1.309     brouard  5300:       else{ /* m = lastpass, eventual special issue with warning */
1.224     brouard  5301: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5302:        break;
1.224     brouard  5303: #else
1.309     brouard  5304:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){ /* case -2 (vital status unknown is warned later */
1.227     brouard  5305:          if(firsthree == 0){
1.302     brouard  5306:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5307:            firsthree=1;
                   5308:          }
1.302     brouard  5309:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.309     brouard  5310:          mw[++mi][i]=m; /* Valid transition with unknown status */
1.227     brouard  5311:          mli=m;
                   5312:        }
                   5313:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5314:          nbwarn++;
1.309     brouard  5315:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified?not a transition */
1.227     brouard  5316:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5317:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5318:          }
                   5319:          break;
                   5320:        }
                   5321:        break;
1.224     brouard  5322: #endif
1.227     brouard  5323:       }/* End m >= lastpass */
1.126     brouard  5324:     }/* end while */
1.224     brouard  5325: 
1.227     brouard  5326:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5327:     /* After last pass */
1.224     brouard  5328: /* Treating death states */
1.214     brouard  5329:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5330:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5331:       /* } */
1.126     brouard  5332:       mi++;    /* Death is another wave */
                   5333:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5334:       /* Only death is a correct wave */
1.126     brouard  5335:       mw[mi][i]=m;
1.257     brouard  5336:     } /* else not in a death state */
1.224     brouard  5337: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5338:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5339:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.309     brouard  5340:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* month of death occured before last wave month and status should have been death instead of -1 */
1.227     brouard  5341:          nbwarn++;
                   5342:          if(firstfiv==0){
1.309     brouard  5343:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5344:            firstfiv=1;
                   5345:          }else{
1.309     brouard  5346:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5347:          }
1.309     brouard  5348:            s[m][i]=nlstate+1; /* Fixing the status as death. Be careful if multiple death states */
                   5349:        }else{ /* Month of Death occured afer last wave month, potential bias */
1.227     brouard  5350:          nberr++;
                   5351:          if(firstwo==0){
1.309     brouard  5352:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5353:            firstwo=1;
                   5354:          }
1.309     brouard  5355:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5356:        }
1.257     brouard  5357:       }else{ /* if date of interview is unknown */
1.227     brouard  5358:        /* death is known but not confirmed by death status at any wave */
                   5359:        if(firstfour==0){
1.309     brouard  5360:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5361:          firstfour=1;
                   5362:        }
1.309     brouard  5363:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d  with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.214     brouard  5364:       }
1.224     brouard  5365:     } /* end if date of death is known */
                   5366: #endif
1.309     brouard  5367:     wav[i]=mi; /* mi should be the last effective wave (or mli),  */
                   5368:     /* wav[i]=mw[mi][i];   */
1.126     brouard  5369:     if(mi==0){
                   5370:       nbwarn++;
                   5371:       if(first==0){
1.227     brouard  5372:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5373:        first=1;
1.126     brouard  5374:       }
                   5375:       if(first==1){
1.227     brouard  5376:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5377:       }
                   5378:     } /* end mi==0 */
                   5379:   } /* End individuals */
1.214     brouard  5380:   /* wav and mw are no more changed */
1.223     brouard  5381:        
1.214     brouard  5382:   
1.126     brouard  5383:   for(i=1; i<=imx; i++){
                   5384:     for(mi=1; mi<wav[i];mi++){
                   5385:       if (stepm <=0)
1.227     brouard  5386:        dh[mi][i]=1;
1.126     brouard  5387:       else{
1.260     brouard  5388:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5389:          if (agedc[i] < 2*AGESUP) {
                   5390:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5391:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5392:            else if(j<0){
                   5393:              nberr++;
                   5394:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5395:              j=1; /* Temporary Dangerous patch */
                   5396:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5397:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5398:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5399:            }
                   5400:            k=k+1;
                   5401:            if (j >= jmax){
                   5402:              jmax=j;
                   5403:              ijmax=i;
                   5404:            }
                   5405:            if (j <= jmin){
                   5406:              jmin=j;
                   5407:              ijmin=i;
                   5408:            }
                   5409:            sum=sum+j;
                   5410:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5411:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5412:          }
                   5413:        }
                   5414:        else{
                   5415:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5416: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5417:                                        
1.227     brouard  5418:          k=k+1;
                   5419:          if (j >= jmax) {
                   5420:            jmax=j;
                   5421:            ijmax=i;
                   5422:          }
                   5423:          else if (j <= jmin){
                   5424:            jmin=j;
                   5425:            ijmin=i;
                   5426:          }
                   5427:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5428:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5429:          if(j<0){
                   5430:            nberr++;
                   5431:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5432:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5433:          }
                   5434:          sum=sum+j;
                   5435:        }
                   5436:        jk= j/stepm;
                   5437:        jl= j -jk*stepm;
                   5438:        ju= j -(jk+1)*stepm;
                   5439:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5440:          if(jl==0){
                   5441:            dh[mi][i]=jk;
                   5442:            bh[mi][i]=0;
                   5443:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5444:                  * to avoid the price of an extra matrix product in likelihood */
                   5445:            dh[mi][i]=jk+1;
                   5446:            bh[mi][i]=ju;
                   5447:          }
                   5448:        }else{
                   5449:          if(jl <= -ju){
                   5450:            dh[mi][i]=jk;
                   5451:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5452:                                 * is higher than the multiple of stepm and negative otherwise.
                   5453:                                 */
                   5454:          }
                   5455:          else{
                   5456:            dh[mi][i]=jk+1;
                   5457:            bh[mi][i]=ju;
                   5458:          }
                   5459:          if(dh[mi][i]==0){
                   5460:            dh[mi][i]=1; /* At least one step */
                   5461:            bh[mi][i]=ju; /* At least one step */
                   5462:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5463:          }
                   5464:        } /* end if mle */
1.126     brouard  5465:       }
                   5466:     } /* end wave */
                   5467:   }
                   5468:   jmean=sum/k;
                   5469:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5470:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5471: }
1.126     brouard  5472: 
                   5473: /*********** Tricode ****************************/
1.220     brouard  5474:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5475:  {
                   5476:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5477:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5478:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5479:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5480:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5481:     */
1.130     brouard  5482: 
1.242     brouard  5483:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5484:    int modmaxcovj=0; /* Modality max of covariates j */
                   5485:    int cptcode=0; /* Modality max of covariates j */
                   5486:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5487: 
                   5488: 
1.242     brouard  5489:    /* cptcoveff=0;  */
                   5490:    /* *cptcov=0; */
1.126     brouard  5491:  
1.242     brouard  5492:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5493:    for (k=1; k <= maxncov; k++)
                   5494:      for(j=1; j<=2; j++)
                   5495:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5496: 
1.242     brouard  5497:    /* Loop on covariates without age and products and no quantitative variable */
                   5498:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5499:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5500:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5501:        switch(Fixed[k]) {
                   5502:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
1.311   ! brouard  5503:         modmaxcovj=0;
        !          5504:         modmincovj=0;
1.242     brouard  5505:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5506:           ij=(int)(covar[Tvar[k]][i]);
                   5507:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5508:            * If product of Vn*Vm, still boolean *:
                   5509:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5510:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5511:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5512:              modality of the nth covariate of individual i. */
                   5513:           if (ij > modmaxcovj)
                   5514:             modmaxcovj=ij; 
                   5515:           else if (ij < modmincovj) 
                   5516:             modmincovj=ij; 
1.287     brouard  5517:           if (ij <0 || ij >1 ){
1.311   ! brouard  5518:             printf("ERROR, IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
        !          5519:             fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
        !          5520:             fflush(ficlog);
        !          5521:             exit(1);
1.287     brouard  5522:           }
                   5523:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5524:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5525:             exit(1);
                   5526:           }else
                   5527:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5528:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5529:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5530:           /* getting the maximum value of the modality of the covariate
                   5531:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5532:              female ies 1, then modmaxcovj=1.
                   5533:           */
                   5534:         } /* end for loop on individuals i */
                   5535:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5536:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5537:         cptcode=modmaxcovj;
                   5538:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5539:         /*for (i=0; i<=cptcode; i++) {*/
                   5540:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5541:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5542:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5543:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5544:             if( j != -1){
                   5545:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5546:                                  covariate for which somebody answered excluding 
                   5547:                                  undefined. Usually 2: 0 and 1. */
                   5548:             }
                   5549:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5550:                                     covariate for which somebody answered including 
                   5551:                                     undefined. Usually 3: -1, 0 and 1. */
                   5552:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5553:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5554:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5555:                        
1.242     brouard  5556:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5557:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5558:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5559:         /* modmincovj=3; modmaxcovj = 7; */
                   5560:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5561:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5562:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5563:         /* nbcode[Tvar[j]][ij]=k; */
                   5564:         /* nbcode[Tvar[j]][1]=0; */
                   5565:         /* nbcode[Tvar[j]][2]=1; */
                   5566:         /* nbcode[Tvar[j]][3]=2; */
                   5567:         /* To be continued (not working yet). */
                   5568:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5569: 
                   5570:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5571:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5572:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5573:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5574:         /*, could be restored in the future */
                   5575:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5576:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5577:             break;
                   5578:           }
                   5579:           ij++;
1.287     brouard  5580:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5581:           cptcode = ij; /* New max modality for covar j */
                   5582:         } /* end of loop on modality i=-1 to 1 or more */
                   5583:         break;
                   5584:        case 1: /* Testing on varying covariate, could be simple and
                   5585:                * should look at waves or product of fixed *
                   5586:                * varying. No time to test -1, assuming 0 and 1 only */
                   5587:         ij=0;
                   5588:         for(i=0; i<=1;i++){
                   5589:           nbcode[Tvar[k]][++ij]=i;
                   5590:         }
                   5591:         break;
                   5592:        default:
                   5593:         break;
                   5594:        } /* end switch */
                   5595:      } /* end dummy test */
1.311   ! brouard  5596:      if(Dummy[k]==1 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
        !          5597:        for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
        !          5598:         if(isnan(covar[Tvar[k]][i])){
        !          5599:           printf("ERROR, IMaCh doesn't treat fixed quantitative covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
        !          5600:           fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
        !          5601:           fflush(ficlog);
        !          5602:           exit(1);
        !          5603:          }
        !          5604:        }
        !          5605:      }
1.287     brouard  5606:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5607:   
                   5608:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5609:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5610:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5611:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5612:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5613:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5614:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5615:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5616:   
                   5617:    ij=0;
                   5618:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5619:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5620:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5621:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5622:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5623:        /* If product not in single variable we don't print results */
                   5624:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5625:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5626:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5627:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5628:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5629:        if(Fixed[k]!=0)
                   5630:         anyvaryingduminmodel=1;
                   5631:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5632:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5633:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5634:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5635:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5636:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5637:      } 
                   5638:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5639:    /* ij--; */
                   5640:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5641:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5642:                * because they can be excluded from the model and real
                   5643:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5644:    for(j=ij+1; j<= cptcovt; j++){
                   5645:      Tvaraff[j]=0;
                   5646:      Tmodelind[j]=0;
                   5647:    }
                   5648:    for(j=ntveff+1; j<= cptcovt; j++){
                   5649:      TmodelInvind[j]=0;
                   5650:    }
                   5651:    /* To be sorted */
                   5652:    ;
                   5653:  }
1.126     brouard  5654: 
1.145     brouard  5655: 
1.126     brouard  5656: /*********** Health Expectancies ****************/
                   5657: 
1.235     brouard  5658:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5659: 
                   5660: {
                   5661:   /* Health expectancies, no variances */
1.164     brouard  5662:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5663:   int nhstepma, nstepma; /* Decreasing with age */
                   5664:   double age, agelim, hf;
                   5665:   double ***p3mat;
                   5666:   double eip;
                   5667: 
1.238     brouard  5668:   /* pstamp(ficreseij); */
1.126     brouard  5669:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5670:   fprintf(ficreseij,"# Age");
                   5671:   for(i=1; i<=nlstate;i++){
                   5672:     for(j=1; j<=nlstate;j++){
                   5673:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5674:     }
                   5675:     fprintf(ficreseij," e%1d. ",i);
                   5676:   }
                   5677:   fprintf(ficreseij,"\n");
                   5678: 
                   5679:   
                   5680:   if(estepm < stepm){
                   5681:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5682:   }
                   5683:   else  hstepm=estepm;   
                   5684:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5685:    * This is mainly to measure the difference between two models: for example
                   5686:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5687:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5688:    * progression in between and thus overestimating or underestimating according
                   5689:    * to the curvature of the survival function. If, for the same date, we 
                   5690:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5691:    * to compare the new estimate of Life expectancy with the same linear 
                   5692:    * hypothesis. A more precise result, taking into account a more precise
                   5693:    * curvature will be obtained if estepm is as small as stepm. */
                   5694: 
                   5695:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5696:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5697:      nhstepm is the number of hstepm from age to agelim 
                   5698:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5699:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5700:      and note for a fixed period like estepm months */
                   5701:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5702:      survival function given by stepm (the optimization length). Unfortunately it
                   5703:      means that if the survival funtion is printed only each two years of age and if
                   5704:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5705:      results. So we changed our mind and took the option of the best precision.
                   5706:   */
                   5707:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5708: 
                   5709:   agelim=AGESUP;
                   5710:   /* If stepm=6 months */
                   5711:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5712:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5713:     
                   5714: /* nhstepm age range expressed in number of stepm */
                   5715:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5716:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5717:   /* if (stepm >= YEARM) hstepm=1;*/
                   5718:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5719:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5720: 
                   5721:   for (age=bage; age<=fage; age ++){ 
                   5722:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5723:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5724:     /* if (stepm >= YEARM) hstepm=1;*/
                   5725:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5726: 
                   5727:     /* If stepm=6 months */
                   5728:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5729:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5730:     
1.235     brouard  5731:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5732:     
                   5733:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5734:     
                   5735:     printf("%d|",(int)age);fflush(stdout);
                   5736:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5737:     
                   5738:     /* Computing expectancies */
                   5739:     for(i=1; i<=nlstate;i++)
                   5740:       for(j=1; j<=nlstate;j++)
                   5741:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5742:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5743:          
                   5744:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5745: 
                   5746:        }
                   5747: 
                   5748:     fprintf(ficreseij,"%3.0f",age );
                   5749:     for(i=1; i<=nlstate;i++){
                   5750:       eip=0;
                   5751:       for(j=1; j<=nlstate;j++){
                   5752:        eip +=eij[i][j][(int)age];
                   5753:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5754:       }
                   5755:       fprintf(ficreseij,"%9.4f", eip );
                   5756:     }
                   5757:     fprintf(ficreseij,"\n");
                   5758:     
                   5759:   }
                   5760:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5761:   printf("\n");
                   5762:   fprintf(ficlog,"\n");
                   5763:   
                   5764: }
                   5765: 
1.235     brouard  5766:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5767: 
                   5768: {
                   5769:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5770:      to initial status i, ei. .
1.126     brouard  5771:   */
                   5772:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5773:   int nhstepma, nstepma; /* Decreasing with age */
                   5774:   double age, agelim, hf;
                   5775:   double ***p3matp, ***p3matm, ***varhe;
                   5776:   double **dnewm,**doldm;
                   5777:   double *xp, *xm;
                   5778:   double **gp, **gm;
                   5779:   double ***gradg, ***trgradg;
                   5780:   int theta;
                   5781: 
                   5782:   double eip, vip;
                   5783: 
                   5784:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5785:   xp=vector(1,npar);
                   5786:   xm=vector(1,npar);
                   5787:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5788:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5789:   
                   5790:   pstamp(ficresstdeij);
                   5791:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5792:   fprintf(ficresstdeij,"# Age");
                   5793:   for(i=1; i<=nlstate;i++){
                   5794:     for(j=1; j<=nlstate;j++)
                   5795:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5796:     fprintf(ficresstdeij," e%1d. ",i);
                   5797:   }
                   5798:   fprintf(ficresstdeij,"\n");
                   5799: 
                   5800:   pstamp(ficrescveij);
                   5801:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5802:   fprintf(ficrescveij,"# Age");
                   5803:   for(i=1; i<=nlstate;i++)
                   5804:     for(j=1; j<=nlstate;j++){
                   5805:       cptj= (j-1)*nlstate+i;
                   5806:       for(i2=1; i2<=nlstate;i2++)
                   5807:        for(j2=1; j2<=nlstate;j2++){
                   5808:          cptj2= (j2-1)*nlstate+i2;
                   5809:          if(cptj2 <= cptj)
                   5810:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5811:        }
                   5812:     }
                   5813:   fprintf(ficrescveij,"\n");
                   5814:   
                   5815:   if(estepm < stepm){
                   5816:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5817:   }
                   5818:   else  hstepm=estepm;   
                   5819:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5820:    * This is mainly to measure the difference between two models: for example
                   5821:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5822:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5823:    * progression in between and thus overestimating or underestimating according
                   5824:    * to the curvature of the survival function. If, for the same date, we 
                   5825:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5826:    * to compare the new estimate of Life expectancy with the same linear 
                   5827:    * hypothesis. A more precise result, taking into account a more precise
                   5828:    * curvature will be obtained if estepm is as small as stepm. */
                   5829: 
                   5830:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5831:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5832:      nhstepm is the number of hstepm from age to agelim 
                   5833:      nstepm is the number of stepm from age to agelin. 
                   5834:      Look at hpijx to understand the reason of that which relies in memory size
                   5835:      and note for a fixed period like estepm months */
                   5836:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5837:      survival function given by stepm (the optimization length). Unfortunately it
                   5838:      means that if the survival funtion is printed only each two years of age and if
                   5839:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5840:      results. So we changed our mind and took the option of the best precision.
                   5841:   */
                   5842:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5843: 
                   5844:   /* If stepm=6 months */
                   5845:   /* nhstepm age range expressed in number of stepm */
                   5846:   agelim=AGESUP;
                   5847:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5848:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5849:   /* if (stepm >= YEARM) hstepm=1;*/
                   5850:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5851:   
                   5852:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5853:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5854:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5855:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5856:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5857:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5858: 
                   5859:   for (age=bage; age<=fage; age ++){ 
                   5860:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5861:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5862:     /* if (stepm >= YEARM) hstepm=1;*/
                   5863:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5864:                
1.126     brouard  5865:     /* If stepm=6 months */
                   5866:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5867:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5868:     
                   5869:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5870:                
1.126     brouard  5871:     /* Computing  Variances of health expectancies */
                   5872:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5873:        decrease memory allocation */
                   5874:     for(theta=1; theta <=npar; theta++){
                   5875:       for(i=1; i<=npar; i++){ 
1.222     brouard  5876:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5877:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5878:       }
1.235     brouard  5879:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5880:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5881:                        
1.126     brouard  5882:       for(j=1; j<= nlstate; j++){
1.222     brouard  5883:        for(i=1; i<=nlstate; i++){
                   5884:          for(h=0; h<=nhstepm-1; h++){
                   5885:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5886:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5887:          }
                   5888:        }
1.126     brouard  5889:       }
1.218     brouard  5890:                        
1.126     brouard  5891:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5892:        for(h=0; h<=nhstepm-1; h++){
                   5893:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5894:        }
1.126     brouard  5895:     }/* End theta */
                   5896:     
                   5897:     
                   5898:     for(h=0; h<=nhstepm-1; h++)
                   5899:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5900:        for(theta=1; theta <=npar; theta++)
                   5901:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5902:     
1.218     brouard  5903:                
1.222     brouard  5904:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5905:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5906:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5907:                
1.222     brouard  5908:     printf("%d|",(int)age);fflush(stdout);
                   5909:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5910:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5911:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5912:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5913:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5914:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5915:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5916:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5917:       }
                   5918:     }
1.218     brouard  5919:                
1.126     brouard  5920:     /* Computing expectancies */
1.235     brouard  5921:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5922:     for(i=1; i<=nlstate;i++)
                   5923:       for(j=1; j<=nlstate;j++)
1.222     brouard  5924:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5925:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5926:                                        
1.222     brouard  5927:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5928:                                        
1.222     brouard  5929:        }
1.269     brouard  5930: 
                   5931:     /* Standard deviation of expectancies ij */                
1.126     brouard  5932:     fprintf(ficresstdeij,"%3.0f",age );
                   5933:     for(i=1; i<=nlstate;i++){
                   5934:       eip=0.;
                   5935:       vip=0.;
                   5936:       for(j=1; j<=nlstate;j++){
1.222     brouard  5937:        eip += eij[i][j][(int)age];
                   5938:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5939:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5940:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5941:       }
                   5942:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5943:     }
                   5944:     fprintf(ficresstdeij,"\n");
1.218     brouard  5945:                
1.269     brouard  5946:     /* Variance of expectancies ij */          
1.126     brouard  5947:     fprintf(ficrescveij,"%3.0f",age );
                   5948:     for(i=1; i<=nlstate;i++)
                   5949:       for(j=1; j<=nlstate;j++){
1.222     brouard  5950:        cptj= (j-1)*nlstate+i;
                   5951:        for(i2=1; i2<=nlstate;i2++)
                   5952:          for(j2=1; j2<=nlstate;j2++){
                   5953:            cptj2= (j2-1)*nlstate+i2;
                   5954:            if(cptj2 <= cptj)
                   5955:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5956:          }
1.126     brouard  5957:       }
                   5958:     fprintf(ficrescveij,"\n");
1.218     brouard  5959:                
1.126     brouard  5960:   }
                   5961:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5962:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5963:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5964:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5965:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5966:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5967:   printf("\n");
                   5968:   fprintf(ficlog,"\n");
1.218     brouard  5969:        
1.126     brouard  5970:   free_vector(xm,1,npar);
                   5971:   free_vector(xp,1,npar);
                   5972:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5973:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5974:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5975: }
1.218     brouard  5976:  
1.126     brouard  5977: /************ Variance ******************/
1.235     brouard  5978:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5979:  {
1.279     brouard  5980:    /** Variance of health expectancies 
                   5981:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   5982:     * double **newm;
                   5983:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   5984:     */
1.218     brouard  5985:   
                   5986:    /* int movingaverage(); */
                   5987:    double **dnewm,**doldm;
                   5988:    double **dnewmp,**doldmp;
                   5989:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  5990:    int first=0;
1.218     brouard  5991:    int k;
                   5992:    double *xp;
1.279     brouard  5993:    double **gp, **gm;  /**< for var eij */
                   5994:    double ***gradg, ***trgradg; /**< for var eij */
                   5995:    double **gradgp, **trgradgp; /**< for var p point j */
                   5996:    double *gpp, *gmp; /**< for var p point j */
                   5997:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  5998:    double ***p3mat;
                   5999:    double age,agelim, hf;
                   6000:    /* double ***mobaverage; */
                   6001:    int theta;
                   6002:    char digit[4];
                   6003:    char digitp[25];
                   6004: 
                   6005:    char fileresprobmorprev[FILENAMELENGTH];
                   6006: 
                   6007:    if(popbased==1){
                   6008:      if(mobilav!=0)
                   6009:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   6010:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   6011:    }
                   6012:    else 
                   6013:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  6014: 
1.218     brouard  6015:    /* if (mobilav!=0) { */
                   6016:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6017:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   6018:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   6019:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   6020:    /*   } */
                   6021:    /* } */
                   6022: 
                   6023:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   6024:    sprintf(digit,"%-d",ij);
                   6025:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   6026:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   6027:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   6028:    strcat(fileresprobmorprev,fileresu);
                   6029:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   6030:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   6031:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   6032:    }
                   6033:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6034:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6035:    pstamp(ficresprobmorprev);
                   6036:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  6037:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   6038:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   6039:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   6040:    }
                   6041:    for(j=1;j<=cptcoveff;j++) 
                   6042:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   6043:    fprintf(ficresprobmorprev,"\n");
                   6044: 
1.218     brouard  6045:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   6046:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6047:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   6048:      for(i=1; i<=nlstate;i++)
                   6049:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   6050:    }  
                   6051:    fprintf(ficresprobmorprev,"\n");
                   6052:   
                   6053:    fprintf(ficgp,"\n# Routine varevsij");
                   6054:    fprintf(ficgp,"\nunset title \n");
                   6055:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   6056:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   6057:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  6058: 
1.218     brouard  6059:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6060:    pstamp(ficresvij);
                   6061:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   6062:    if(popbased==1)
                   6063:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   6064:    else
                   6065:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   6066:    fprintf(ficresvij,"# Age");
                   6067:    for(i=1; i<=nlstate;i++)
                   6068:      for(j=1; j<=nlstate;j++)
                   6069:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   6070:    fprintf(ficresvij,"\n");
                   6071: 
                   6072:    xp=vector(1,npar);
                   6073:    dnewm=matrix(1,nlstate,1,npar);
                   6074:    doldm=matrix(1,nlstate,1,nlstate);
                   6075:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   6076:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6077: 
                   6078:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   6079:    gpp=vector(nlstate+1,nlstate+ndeath);
                   6080:    gmp=vector(nlstate+1,nlstate+ndeath);
                   6081:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  6082:   
1.218     brouard  6083:    if(estepm < stepm){
                   6084:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   6085:    }
                   6086:    else  hstepm=estepm;   
                   6087:    /* For example we decided to compute the life expectancy with the smallest unit */
                   6088:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6089:       nhstepm is the number of hstepm from age to agelim 
                   6090:       nstepm is the number of stepm from age to agelim. 
                   6091:       Look at function hpijx to understand why because of memory size limitations, 
                   6092:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   6093:       survival function given by stepm (the optimization length). Unfortunately it
                   6094:       means that if the survival funtion is printed every two years of age and if
                   6095:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6096:       results. So we changed our mind and took the option of the best precision.
                   6097:    */
                   6098:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6099:    agelim = AGESUP;
                   6100:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6101:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6102:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6103:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6104:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   6105:      gp=matrix(0,nhstepm,1,nlstate);
                   6106:      gm=matrix(0,nhstepm,1,nlstate);
                   6107:                
                   6108:                
                   6109:      for(theta=1; theta <=npar; theta++){
                   6110:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   6111:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6112:        }
1.279     brouard  6113:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   6114:        * returns into prlim .
1.288     brouard  6115:        */
1.242     brouard  6116:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  6117: 
                   6118:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6119:        if (popbased==1) {
                   6120:         if(mobilav ==0){
                   6121:           for(i=1; i<=nlstate;i++)
                   6122:             prlim[i][i]=probs[(int)age][i][ij];
                   6123:         }else{ /* mobilav */ 
                   6124:           for(i=1; i<=nlstate;i++)
                   6125:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6126:         }
                   6127:        }
1.295     brouard  6128:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}x\f$ at horizon h.
1.279     brouard  6129:        */                      
                   6130:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292     brouard  6131:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6132:        * at horizon h in state j including mortality.
                   6133:        */
1.218     brouard  6134:        for(j=1; j<= nlstate; j++){
                   6135:         for(h=0; h<=nhstepm; h++){
                   6136:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6137:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6138:         }
                   6139:        }
1.279     brouard  6140:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6141:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6142:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6143:        */
                   6144:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6145:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6146:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6147:        }
                   6148:        
                   6149:        /* Again with minus shift */
1.218     brouard  6150:                        
                   6151:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6152:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6153: 
1.242     brouard  6154:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6155:                        
                   6156:        if (popbased==1) {
                   6157:         if(mobilav ==0){
                   6158:           for(i=1; i<=nlstate;i++)
                   6159:             prlim[i][i]=probs[(int)age][i][ij];
                   6160:         }else{ /* mobilav */ 
                   6161:           for(i=1; i<=nlstate;i++)
                   6162:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6163:         }
                   6164:        }
                   6165:                        
1.235     brouard  6166:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6167:                        
                   6168:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6169:         for(h=0; h<=nhstepm; h++){
                   6170:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6171:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6172:         }
                   6173:        }
                   6174:        /* This for computing probability of death (h=1 means
                   6175:          computed over hstepm matrices product = hstepm*stepm months) 
                   6176:          as a weighted average of prlim.
                   6177:        */
                   6178:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6179:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6180:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6181:        }    
1.279     brouard  6182:        /* end shifting computations */
                   6183: 
                   6184:        /**< Computing gradient matrix at horizon h 
                   6185:        */
1.218     brouard  6186:        for(j=1; j<= nlstate; j++) /* vareij */
                   6187:         for(h=0; h<=nhstepm; h++){
                   6188:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6189:         }
1.279     brouard  6190:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6191:        */
                   6192:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6193:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6194:        }
                   6195:                        
                   6196:      } /* End theta */
1.279     brouard  6197:      
                   6198:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6199:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6200:                
                   6201:      for(h=0; h<=nhstepm; h++) /* veij */
                   6202:        for(j=1; j<=nlstate;j++)
                   6203:         for(theta=1; theta <=npar; theta++)
                   6204:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6205:                
                   6206:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6207:        for(theta=1; theta <=npar; theta++)
                   6208:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6209:      /**< as well as its transposed matrix 
                   6210:       */               
1.218     brouard  6211:                
                   6212:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6213:      for(i=1;i<=nlstate;i++)
                   6214:        for(j=1;j<=nlstate;j++)
                   6215:         vareij[i][j][(int)age] =0.;
1.279     brouard  6216: 
                   6217:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6218:       * and k (nhstepm) formula 15 of article
                   6219:       * Lievre-Brouard-Heathcote
                   6220:       */
                   6221:      
1.218     brouard  6222:      for(h=0;h<=nhstepm;h++){
                   6223:        for(k=0;k<=nhstepm;k++){
                   6224:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6225:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6226:         for(i=1;i<=nlstate;i++)
                   6227:           for(j=1;j<=nlstate;j++)
                   6228:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6229:        }
                   6230:      }
                   6231:                
1.279     brouard  6232:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6233:       * p.j overall mortality formula 49 but computed directly because
                   6234:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6235:       * wix is independent of theta.
                   6236:       */
1.218     brouard  6237:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6238:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6239:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6240:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6241:         varppt[j][i]=doldmp[j][i];
                   6242:      /* end ppptj */
                   6243:      /*  x centered again */
                   6244:                
1.242     brouard  6245:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6246:                
                   6247:      if (popbased==1) {
                   6248:        if(mobilav ==0){
                   6249:         for(i=1; i<=nlstate;i++)
                   6250:           prlim[i][i]=probs[(int)age][i][ij];
                   6251:        }else{ /* mobilav */ 
                   6252:         for(i=1; i<=nlstate;i++)
                   6253:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6254:        }
                   6255:      }
                   6256:                
                   6257:      /* This for computing probability of death (h=1 means
                   6258:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6259:        as a weighted average of prlim.
                   6260:      */
1.235     brouard  6261:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6262:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6263:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6264:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6265:      }    
                   6266:      /* end probability of death */
                   6267:                
                   6268:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6269:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6270:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6271:        for(i=1; i<=nlstate;i++){
                   6272:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6273:        }
                   6274:      } 
                   6275:      fprintf(ficresprobmorprev,"\n");
                   6276:                
                   6277:      fprintf(ficresvij,"%.0f ",age );
                   6278:      for(i=1; i<=nlstate;i++)
                   6279:        for(j=1; j<=nlstate;j++){
                   6280:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6281:        }
                   6282:      fprintf(ficresvij,"\n");
                   6283:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6284:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6285:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6286:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6287:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6288:    } /* End age */
                   6289:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6290:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6291:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6292:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6293:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6294:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6295:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6296:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6297:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6298:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6299:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6300:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6301:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6302:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6303:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6304:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6305:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6306:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6307:     */
1.218     brouard  6308:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6309:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6310: 
1.218     brouard  6311:    free_vector(xp,1,npar);
                   6312:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6313:    free_matrix(dnewm,1,nlstate,1,npar);
                   6314:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6315:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6316:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6317:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6318:    fclose(ficresprobmorprev);
                   6319:    fflush(ficgp);
                   6320:    fflush(fichtm); 
                   6321:  }  /* end varevsij */
1.126     brouard  6322: 
                   6323: /************ Variance of prevlim ******************/
1.269     brouard  6324:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6325: {
1.205     brouard  6326:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6327:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6328: 
1.268     brouard  6329:   double **dnewmpar,**doldm;
1.126     brouard  6330:   int i, j, nhstepm, hstepm;
                   6331:   double *xp;
                   6332:   double *gp, *gm;
                   6333:   double **gradg, **trgradg;
1.208     brouard  6334:   double **mgm, **mgp;
1.126     brouard  6335:   double age,agelim;
                   6336:   int theta;
                   6337:   
                   6338:   pstamp(ficresvpl);
1.288     brouard  6339:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6340:   fprintf(ficresvpl,"# Age ");
                   6341:   if(nresult >=1)
                   6342:     fprintf(ficresvpl," Result# ");
1.126     brouard  6343:   for(i=1; i<=nlstate;i++)
                   6344:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6345:   fprintf(ficresvpl,"\n");
                   6346: 
                   6347:   xp=vector(1,npar);
1.268     brouard  6348:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6349:   doldm=matrix(1,nlstate,1,nlstate);
                   6350:   
                   6351:   hstepm=1*YEARM; /* Every year of age */
                   6352:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6353:   agelim = AGESUP;
                   6354:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6355:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6356:     if (stepm >= YEARM) hstepm=1;
                   6357:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6358:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6359:     mgp=matrix(1,npar,1,nlstate);
                   6360:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6361:     gp=vector(1,nlstate);
                   6362:     gm=vector(1,nlstate);
                   6363: 
                   6364:     for(theta=1; theta <=npar; theta++){
                   6365:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6366:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6367:       }
1.288     brouard  6368:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6369:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6370:       /* else */
                   6371:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6372:       for(i=1;i<=nlstate;i++){
1.126     brouard  6373:        gp[i] = prlim[i][i];
1.208     brouard  6374:        mgp[theta][i] = prlim[i][i];
                   6375:       }
1.126     brouard  6376:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6377:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6378:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6379:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6380:       /* else */
                   6381:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6382:       for(i=1;i<=nlstate;i++){
1.126     brouard  6383:        gm[i] = prlim[i][i];
1.208     brouard  6384:        mgm[theta][i] = prlim[i][i];
                   6385:       }
1.126     brouard  6386:       for(i=1;i<=nlstate;i++)
                   6387:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6388:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6389:     } /* End theta */
                   6390: 
                   6391:     trgradg =matrix(1,nlstate,1,npar);
                   6392: 
                   6393:     for(j=1; j<=nlstate;j++)
                   6394:       for(theta=1; theta <=npar; theta++)
                   6395:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6396:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6397:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6398:     /*   for(j=1; j<=nlstate;j++){ */
                   6399:     /*         printf(" %d ",j); */
                   6400:     /*         for(theta=1; theta <=npar; theta++) */
                   6401:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6402:     /*         printf("\n "); */
                   6403:     /*   } */
                   6404:     /* } */
                   6405:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6406:     /*   printf("\n gradg %d ",(int)age); */
                   6407:     /*   for(j=1; j<=nlstate;j++){ */
                   6408:     /*         printf("%d ",j); */
                   6409:     /*         for(theta=1; theta <=npar; theta++) */
                   6410:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6411:     /*         printf("\n "); */
                   6412:     /*   } */
                   6413:     /* } */
1.126     brouard  6414: 
                   6415:     for(i=1;i<=nlstate;i++)
                   6416:       varpl[i][(int)age] =0.;
1.209     brouard  6417:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6418:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6419:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6420:     }else{
1.268     brouard  6421:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6422:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6423:     }
1.126     brouard  6424:     for(i=1;i<=nlstate;i++)
                   6425:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6426: 
                   6427:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6428:     if(nresult >=1)
                   6429:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6430:     for(i=1; i<=nlstate;i++){
1.126     brouard  6431:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6432:       /* for(j=1;j<=nlstate;j++) */
                   6433:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6434:     }
1.126     brouard  6435:     fprintf(ficresvpl,"\n");
                   6436:     free_vector(gp,1,nlstate);
                   6437:     free_vector(gm,1,nlstate);
1.208     brouard  6438:     free_matrix(mgm,1,npar,1,nlstate);
                   6439:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6440:     free_matrix(gradg,1,npar,1,nlstate);
                   6441:     free_matrix(trgradg,1,nlstate,1,npar);
                   6442:   } /* End age */
                   6443: 
                   6444:   free_vector(xp,1,npar);
                   6445:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6446:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6447: 
                   6448: }
                   6449: 
                   6450: 
                   6451: /************ Variance of backprevalence limit ******************/
1.269     brouard  6452:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6453: {
                   6454:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6455:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6456: 
                   6457:   double **dnewmpar,**doldm;
                   6458:   int i, j, nhstepm, hstepm;
                   6459:   double *xp;
                   6460:   double *gp, *gm;
                   6461:   double **gradg, **trgradg;
                   6462:   double **mgm, **mgp;
                   6463:   double age,agelim;
                   6464:   int theta;
                   6465:   
                   6466:   pstamp(ficresvbl);
                   6467:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6468:   fprintf(ficresvbl,"# Age ");
                   6469:   if(nresult >=1)
                   6470:     fprintf(ficresvbl," Result# ");
                   6471:   for(i=1; i<=nlstate;i++)
                   6472:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6473:   fprintf(ficresvbl,"\n");
                   6474: 
                   6475:   xp=vector(1,npar);
                   6476:   dnewmpar=matrix(1,nlstate,1,npar);
                   6477:   doldm=matrix(1,nlstate,1,nlstate);
                   6478:   
                   6479:   hstepm=1*YEARM; /* Every year of age */
                   6480:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6481:   agelim = AGEINF;
                   6482:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6483:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6484:     if (stepm >= YEARM) hstepm=1;
                   6485:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6486:     gradg=matrix(1,npar,1,nlstate);
                   6487:     mgp=matrix(1,npar,1,nlstate);
                   6488:     mgm=matrix(1,npar,1,nlstate);
                   6489:     gp=vector(1,nlstate);
                   6490:     gm=vector(1,nlstate);
                   6491: 
                   6492:     for(theta=1; theta <=npar; theta++){
                   6493:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6494:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6495:       }
                   6496:       if(mobilavproj > 0 )
                   6497:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6498:       else
                   6499:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6500:       for(i=1;i<=nlstate;i++){
                   6501:        gp[i] = bprlim[i][i];
                   6502:        mgp[theta][i] = bprlim[i][i];
                   6503:       }
                   6504:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6505:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6506:        if(mobilavproj > 0 )
                   6507:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6508:        else
                   6509:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6510:       for(i=1;i<=nlstate;i++){
                   6511:        gm[i] = bprlim[i][i];
                   6512:        mgm[theta][i] = bprlim[i][i];
                   6513:       }
                   6514:       for(i=1;i<=nlstate;i++)
                   6515:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6516:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6517:     } /* End theta */
                   6518: 
                   6519:     trgradg =matrix(1,nlstate,1,npar);
                   6520: 
                   6521:     for(j=1; j<=nlstate;j++)
                   6522:       for(theta=1; theta <=npar; theta++)
                   6523:        trgradg[j][theta]=gradg[theta][j];
                   6524:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6525:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6526:     /*   for(j=1; j<=nlstate;j++){ */
                   6527:     /*         printf(" %d ",j); */
                   6528:     /*         for(theta=1; theta <=npar; theta++) */
                   6529:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6530:     /*         printf("\n "); */
                   6531:     /*   } */
                   6532:     /* } */
                   6533:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6534:     /*   printf("\n gradg %d ",(int)age); */
                   6535:     /*   for(j=1; j<=nlstate;j++){ */
                   6536:     /*         printf("%d ",j); */
                   6537:     /*         for(theta=1; theta <=npar; theta++) */
                   6538:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6539:     /*         printf("\n "); */
                   6540:     /*   } */
                   6541:     /* } */
                   6542: 
                   6543:     for(i=1;i<=nlstate;i++)
                   6544:       varbpl[i][(int)age] =0.;
                   6545:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6546:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6547:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6548:     }else{
                   6549:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6550:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6551:     }
                   6552:     for(i=1;i<=nlstate;i++)
                   6553:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6554: 
                   6555:     fprintf(ficresvbl,"%.0f ",age );
                   6556:     if(nresult >=1)
                   6557:       fprintf(ficresvbl,"%d ",nres );
                   6558:     for(i=1; i<=nlstate;i++)
                   6559:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6560:     fprintf(ficresvbl,"\n");
                   6561:     free_vector(gp,1,nlstate);
                   6562:     free_vector(gm,1,nlstate);
                   6563:     free_matrix(mgm,1,npar,1,nlstate);
                   6564:     free_matrix(mgp,1,npar,1,nlstate);
                   6565:     free_matrix(gradg,1,npar,1,nlstate);
                   6566:     free_matrix(trgradg,1,nlstate,1,npar);
                   6567:   } /* End age */
                   6568: 
                   6569:   free_vector(xp,1,npar);
                   6570:   free_matrix(doldm,1,nlstate,1,npar);
                   6571:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6572: 
                   6573: }
                   6574: 
                   6575: /************ Variance of one-step probabilities  ******************/
                   6576: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6577:  {
                   6578:    int i, j=0,  k1, l1, tj;
                   6579:    int k2, l2, j1,  z1;
                   6580:    int k=0, l;
                   6581:    int first=1, first1, first2;
                   6582:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6583:    double **dnewm,**doldm;
                   6584:    double *xp;
                   6585:    double *gp, *gm;
                   6586:    double **gradg, **trgradg;
                   6587:    double **mu;
                   6588:    double age, cov[NCOVMAX+1];
                   6589:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6590:    int theta;
                   6591:    char fileresprob[FILENAMELENGTH];
                   6592:    char fileresprobcov[FILENAMELENGTH];
                   6593:    char fileresprobcor[FILENAMELENGTH];
                   6594:    double ***varpij;
                   6595: 
                   6596:    strcpy(fileresprob,"PROB_"); 
                   6597:    strcat(fileresprob,fileres);
                   6598:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6599:      printf("Problem with resultfile: %s\n", fileresprob);
                   6600:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6601:    }
                   6602:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6603:    strcat(fileresprobcov,fileresu);
                   6604:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6605:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6606:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6607:    }
                   6608:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6609:    strcat(fileresprobcor,fileresu);
                   6610:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6611:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6612:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6613:    }
                   6614:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6615:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6616:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6617:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6618:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6619:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6620:    pstamp(ficresprob);
                   6621:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6622:    fprintf(ficresprob,"# Age");
                   6623:    pstamp(ficresprobcov);
                   6624:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6625:    fprintf(ficresprobcov,"# Age");
                   6626:    pstamp(ficresprobcor);
                   6627:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6628:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6629: 
                   6630: 
1.222     brouard  6631:    for(i=1; i<=nlstate;i++)
                   6632:      for(j=1; j<=(nlstate+ndeath);j++){
                   6633:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6634:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6635:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6636:      }  
                   6637:    /* fprintf(ficresprob,"\n");
                   6638:       fprintf(ficresprobcov,"\n");
                   6639:       fprintf(ficresprobcor,"\n");
                   6640:    */
                   6641:    xp=vector(1,npar);
                   6642:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6643:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6644:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6645:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6646:    first=1;
                   6647:    fprintf(ficgp,"\n# Routine varprob");
                   6648:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6649:    fprintf(fichtm,"\n");
                   6650: 
1.288     brouard  6651:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6652:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6653:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6654: and drawn. It helps understanding how is the covariance between two incidences.\
                   6655:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6656:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6657: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6658: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6659: standard deviations wide on each axis. <br>\
                   6660:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6661:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6662: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6663: 
1.222     brouard  6664:    cov[1]=1;
                   6665:    /* tj=cptcoveff; */
1.225     brouard  6666:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6667:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6668:    j1=0;
1.224     brouard  6669:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6670:      if  (cptcovn>0) {
                   6671:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6672:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6673:        fprintf(ficresprob, "**********\n#\n");
                   6674:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6675:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6676:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6677:                        
1.222     brouard  6678:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6679:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6680:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6681:                        
                   6682:                        
1.222     brouard  6683:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6684:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6685:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6686:                        
1.222     brouard  6687:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6688:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6689:        fprintf(ficresprobcor, "**********\n#");    
                   6690:        if(invalidvarcomb[j1]){
                   6691:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6692:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6693:         continue;
                   6694:        }
                   6695:      }
                   6696:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6697:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6698:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6699:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6700:      for (age=bage; age<=fage; age ++){ 
                   6701:        cov[2]=age;
                   6702:        if(nagesqr==1)
                   6703:         cov[3]= age*age;
                   6704:        for (k=1; k<=cptcovn;k++) {
                   6705:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6706:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6707:                                                                    * 1  1 1 1 1
                   6708:                                                                    * 2  2 1 1 1
                   6709:                                                                    * 3  1 2 1 1
                   6710:                                                                    */
                   6711:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6712:        }
                   6713:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6714:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6715:        for (k=1; k<=cptcovprod;k++)
                   6716:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6717:                        
                   6718:                        
1.222     brouard  6719:        for(theta=1; theta <=npar; theta++){
                   6720:         for(i=1; i<=npar; i++)
                   6721:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6722:                                
1.222     brouard  6723:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6724:                                
1.222     brouard  6725:         k=0;
                   6726:         for(i=1; i<= (nlstate); i++){
                   6727:           for(j=1; j<=(nlstate+ndeath);j++){
                   6728:             k=k+1;
                   6729:             gp[k]=pmmij[i][j];
                   6730:           }
                   6731:         }
1.220     brouard  6732:                                
1.222     brouard  6733:         for(i=1; i<=npar; i++)
                   6734:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6735:                                
1.222     brouard  6736:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6737:         k=0;
                   6738:         for(i=1; i<=(nlstate); i++){
                   6739:           for(j=1; j<=(nlstate+ndeath);j++){
                   6740:             k=k+1;
                   6741:             gm[k]=pmmij[i][j];
                   6742:           }
                   6743:         }
1.220     brouard  6744:                                
1.222     brouard  6745:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6746:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6747:        }
1.126     brouard  6748: 
1.222     brouard  6749:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6750:         for(theta=1; theta <=npar; theta++)
                   6751:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6752:                        
1.222     brouard  6753:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6754:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6755:                        
1.222     brouard  6756:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6757:                        
1.222     brouard  6758:        k=0;
                   6759:        for(i=1; i<=(nlstate); i++){
                   6760:         for(j=1; j<=(nlstate+ndeath);j++){
                   6761:           k=k+1;
                   6762:           mu[k][(int) age]=pmmij[i][j];
                   6763:         }
                   6764:        }
                   6765:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6766:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6767:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6768:                        
1.222     brouard  6769:        /*printf("\n%d ",(int)age);
                   6770:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6771:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6772:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6773:         }*/
1.220     brouard  6774:                        
1.222     brouard  6775:        fprintf(ficresprob,"\n%d ",(int)age);
                   6776:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6777:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6778:                        
1.222     brouard  6779:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6780:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6781:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6782:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6783:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6784:        }
                   6785:        i=0;
                   6786:        for (k=1; k<=(nlstate);k++){
                   6787:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6788:           i++;
                   6789:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6790:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6791:           for (j=1; j<=i;j++){
                   6792:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6793:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6794:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6795:           }
                   6796:         }
                   6797:        }/* end of loop for state */
                   6798:      } /* end of loop for age */
                   6799:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6800:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6801:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6802:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6803:     
                   6804:      /* Confidence intervalle of pij  */
                   6805:      /*
                   6806:        fprintf(ficgp,"\nunset parametric;unset label");
                   6807:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6808:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6809:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6810:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6811:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6812:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6813:      */
                   6814:                
                   6815:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6816:      first1=1;first2=2;
                   6817:      for (k2=1; k2<=(nlstate);k2++){
                   6818:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6819:         if(l2==k2) continue;
                   6820:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6821:         for (k1=1; k1<=(nlstate);k1++){
                   6822:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6823:             if(l1==k1) continue;
                   6824:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6825:             if(i<=j) continue;
                   6826:             for (age=bage; age<=fage; age ++){ 
                   6827:               if ((int)age %5==0){
                   6828:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6829:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6830:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6831:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6832:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6833:                 c12=cv12/sqrt(v1*v2);
                   6834:                 /* Computing eigen value of matrix of covariance */
                   6835:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6836:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6837:                 if ((lc2 <0) || (lc1 <0) ){
                   6838:                   if(first2==1){
                   6839:                     first1=0;
                   6840:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6841:                   }
                   6842:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6843:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6844:                   /* lc2=fabs(lc2); */
                   6845:                 }
1.220     brouard  6846:                                                                
1.222     brouard  6847:                 /* Eigen vectors */
1.280     brouard  6848:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6849:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6850:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6851:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6852:                 }else
                   6853:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6854:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6855:                 v21=(lc1-v1)/cv12*v11;
                   6856:                 v12=-v21;
                   6857:                 v22=v11;
                   6858:                 tnalp=v21/v11;
                   6859:                 if(first1==1){
                   6860:                   first1=0;
                   6861:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6862:                 }
                   6863:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6864:                 /*printf(fignu*/
                   6865:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6866:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6867:                 if(first==1){
                   6868:                   first=0;
                   6869:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6870:                   fprintf(ficgp,"\nset parametric;unset label");
                   6871:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6872:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6873:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6874:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6875: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6876:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6877:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6878:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6879:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6880:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6881:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6882:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6883:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6884:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6885:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6886:                 }else{
                   6887:                   first=0;
                   6888:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6889:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6890:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6891:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6892:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6893:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6894:                 }/* if first */
                   6895:               } /* age mod 5 */
                   6896:             } /* end loop age */
                   6897:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6898:             first=1;
                   6899:           } /*l12 */
                   6900:         } /* k12 */
                   6901:        } /*l1 */
                   6902:      }/* k1 */
                   6903:    }  /* loop on combination of covariates j1 */
                   6904:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6905:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6906:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6907:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6908:    free_vector(xp,1,npar);
                   6909:    fclose(ficresprob);
                   6910:    fclose(ficresprobcov);
                   6911:    fclose(ficresprobcor);
                   6912:    fflush(ficgp);
                   6913:    fflush(fichtmcov);
                   6914:  }
1.126     brouard  6915: 
                   6916: 
                   6917: /******************* Printing html file ***********/
1.201     brouard  6918: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6919:                  int lastpass, int stepm, int weightopt, char model[],\
                   6920:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.296     brouard  6921:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int prevbcast, int estepm , \
                   6922:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateprojd, double dateback1, \
                   6923:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateprojf, double dateback2){
1.237     brouard  6924:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6925: 
                   6926:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6927:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6928: </ul>");
1.237     brouard  6929:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6930: </ul>", model);
1.214     brouard  6931:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6932:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6933:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6934:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6935:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6936:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6937:    fprintf(fichtm,"\
                   6938:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6939:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6940:    fprintf(fichtm,"\
1.217     brouard  6941:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6942:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6943:    fprintf(fichtm,"\
1.288     brouard  6944:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6945:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6946:    fprintf(fichtm,"\
1.288     brouard  6947:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  6948:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6949:    fprintf(fichtm,"\
1.211     brouard  6950:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6951:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6952:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6953:    if(prevfcast==1){
                   6954:      fprintf(fichtm,"\
                   6955:  - Prevalence projections by age and states:                           \
1.201     brouard  6956:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6957:    }
1.126     brouard  6958: 
                   6959: 
1.225     brouard  6960:    m=pow(2,cptcoveff);
1.222     brouard  6961:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6962: 
1.264     brouard  6963:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6964: 
                   6965:    jj1=0;
                   6966: 
                   6967:    fprintf(fichtm," \n<ul>");
                   6968:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6969:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6970:      if(m != 1 && TKresult[nres]!= k1)
                   6971:        continue;
                   6972:      jj1++;
                   6973:      if (cptcovn > 0) {
                   6974:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6975:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6976:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6977:        }
                   6978:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6979:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6980:        }
                   6981:        fprintf(fichtm,"\">");
                   6982:        
                   6983:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   6984:        fprintf(fichtm,"************ Results for covariates");
                   6985:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6986:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6987:        }
                   6988:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6989:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   6990:        }
                   6991:        if(invalidvarcomb[k1]){
                   6992:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   6993:         continue;
                   6994:        }
                   6995:        fprintf(fichtm,"</a></li>");
                   6996:      } /* cptcovn >0 */
                   6997:    }
                   6998:      fprintf(fichtm," \n</ul>");
                   6999: 
1.222     brouard  7000:    jj1=0;
1.237     brouard  7001: 
                   7002:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  7003:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  7004:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7005:        continue;
1.220     brouard  7006: 
1.222     brouard  7007:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7008:      jj1++;
                   7009:      if (cptcovn > 0) {
1.264     brouard  7010:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   7011:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7012:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7013:        }
                   7014:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7015:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7016:        }
                   7017:        fprintf(fichtm,"\"</a>");
                   7018:  
1.222     brouard  7019:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7020:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  7021:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7022:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   7023:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7024:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  7025:        }
1.237     brouard  7026:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7027:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7028:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   7029:       }
                   7030:        
1.230     brouard  7031:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  7032:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   7033:        if(invalidvarcomb[k1]){
                   7034:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   7035:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   7036:         continue;
                   7037:        }
                   7038:      }
                   7039:      /* aij, bij */
1.259     brouard  7040:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  7041: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  7042:      /* Pij */
1.241     brouard  7043:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   7044: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  7045:      /* Quasi-incidences */
                   7046:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  7047:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  7048:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  7049: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   7050: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  7051:      /* Survival functions (period) in state j */
                   7052:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7053:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7054: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  7055:      }
                   7056:      /* State specific survival functions (period) */
                   7057:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7058:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
                   7059:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  7060:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  7061:      }
1.288     brouard  7062:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  7063:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7064:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7065: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  7066:      }
1.296     brouard  7067:      if(prevbcast==1){
1.288     brouard  7068:        /* Backward prevalence in each health state */
1.222     brouard  7069:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7070:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7071: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  7072:        }
1.217     brouard  7073:      }
1.222     brouard  7074:      if(prevfcast==1){
1.288     brouard  7075:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  7076:        for(cpt=1; cpt<=nlstate;cpt++){
1.288     brouard  7077:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.296     brouard  7078: <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateprojd, dateprojf, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  7079:        }
                   7080:      }
1.296     brouard  7081:      if(prevbcast==1){
1.268     brouard  7082:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   7083:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  7084:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   7085:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   7086:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
                   7087: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7088:  <img src=\"%s_%d-%d-%d.svg\">", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  7089:        }
                   7090:      }
1.220     brouard  7091:         
1.222     brouard  7092:      for(cpt=1; cpt<=nlstate;cpt++) {
1.241     brouard  7093:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a> <br> \
                   7094: <img src=\"%s_%d-%d-%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.222     brouard  7095:      }
                   7096:      /* } /\* end i1 *\/ */
                   7097:    }/* End k1 */
                   7098:    fprintf(fichtm,"</ul>");
1.126     brouard  7099: 
1.222     brouard  7100:    fprintf(fichtm,"\
1.126     brouard  7101: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  7102:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  7103:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  7104: But because parameters are usually highly correlated (a higher incidence of disability \
                   7105: and a higher incidence of recovery can give very close observed transition) it might \
                   7106: be very useful to look not only at linear confidence intervals estimated from the \
                   7107: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   7108: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   7109: covariance matrix of the one-step probabilities. \
                   7110: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  7111: 
1.222     brouard  7112:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   7113:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   7114:    fprintf(fichtm,"\
1.126     brouard  7115:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7116:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  7117: 
1.222     brouard  7118:    fprintf(fichtm,"\
1.126     brouard  7119:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7120:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7121:    fprintf(fichtm,"\
1.126     brouard  7122:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7123:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7124:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7125:    fprintf(fichtm,"\
1.126     brouard  7126:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7127:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7128:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7129:    fprintf(fichtm,"\
1.288     brouard  7130:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7131:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7132:    fprintf(fichtm,"\
1.128     brouard  7133:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7134:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7135:    fprintf(fichtm,"\
1.288     brouard  7136:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7137:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7138: 
                   7139: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7140: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7141: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7142: /*     <br>",fileres,fileres,fileres,fileres); */
                   7143: /*  else  */
                   7144: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7145:    fflush(fichtm);
                   7146:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7147: 
1.225     brouard  7148:    m=pow(2,cptcoveff);
1.222     brouard  7149:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7150: 
1.222     brouard  7151:    jj1=0;
1.237     brouard  7152: 
1.241     brouard  7153:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7154:    for(k1=1; k1<=m;k1++){
1.253     brouard  7155:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7156:        continue;
1.222     brouard  7157:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7158:      jj1++;
1.126     brouard  7159:      if (cptcovn > 0) {
                   7160:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7161:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7162:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7163:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7164:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7165:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7166:       }
                   7167: 
1.126     brouard  7168:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7169: 
1.222     brouard  7170:        if(invalidvarcomb[k1]){
                   7171:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7172:         continue;
                   7173:        }
1.126     brouard  7174:      }
                   7175:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7176:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.241     brouard  7177: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>\n <br>\
1.258     brouard  7178: <img src=\"%s_%d-%d-%d.svg\">",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);  
1.126     brouard  7179:      }
                   7180:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.128     brouard  7181: health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
                   7182: true period expectancies (those weighted with period prevalences are also\
                   7183:  drawn in addition to the population based expectancies computed using\
1.241     brouard  7184:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>\n<br>\
                   7185: <img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7186:      /* } /\* end i1 *\/ */
                   7187:    }/* End k1 */
1.241     brouard  7188:   }/* End nres */
1.222     brouard  7189:    fprintf(fichtm,"</ul>");
                   7190:    fflush(fichtm);
1.126     brouard  7191: }
                   7192: 
                   7193: /******************* Gnuplot file **************/
1.296     brouard  7194: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int prevbcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7195: 
                   7196:   char dirfileres[132],optfileres[132];
1.264     brouard  7197:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7198:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7199:   int lv=0, vlv=0, kl=0;
1.130     brouard  7200:   int ng=0;
1.201     brouard  7201:   int vpopbased;
1.223     brouard  7202:   int ioffset; /* variable offset for columns */
1.270     brouard  7203:   int iyearc=1; /* variable column for year of projection  */
                   7204:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7205:   int nres=0; /* Index of resultline */
1.266     brouard  7206:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7207: 
1.126     brouard  7208: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7209: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7210: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7211: /*   } */
                   7212: 
                   7213:   /*#ifdef windows */
                   7214:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7215:   /*#endif */
1.225     brouard  7216:   m=pow(2,cptcoveff);
1.126     brouard  7217: 
1.274     brouard  7218:   /* diagram of the model */
                   7219:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7220:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7221:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7222:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7223: 
                   7224:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7225:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7226:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7227:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7228:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7229:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7230:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7231: 
1.202     brouard  7232:   /* Contribution to likelihood */
                   7233:   /* Plot the probability implied in the likelihood */
1.223     brouard  7234:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7235:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7236:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7237:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7238: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7239:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7240: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7241:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7242:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7243:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7244:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7245:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7246:   for (i=1; i<= nlstate ; i ++) {
                   7247:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7248:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7249:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7250:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7251:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7252:     }
                   7253:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7254:   }
                   7255:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7256:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7257:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7258:   fprintf(ficgp,"\nset out;unset log\n");
                   7259:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7260: 
1.126     brouard  7261:   strcpy(dirfileres,optionfilefiname);
                   7262:   strcpy(optfileres,"vpl");
1.223     brouard  7263:   /* 1eme*/
1.238     brouard  7264:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7265:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7266:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7267:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7268:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7269:          continue;
                   7270:        /* We are interested in selected combination by the resultline */
1.246     brouard  7271:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7272:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7273:        strcpy(gplotlabel,"(");
1.238     brouard  7274:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7275:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7276:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7277:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7278:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7279:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7280:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7281:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7282:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7283:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7284:        }
                   7285:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7286:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7287:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7288:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7289:        }
                   7290:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7291:        /* printf("\n#\n"); */
1.238     brouard  7292:        fprintf(ficgp,"\n#\n");
                   7293:        if(invalidvarcomb[k1]){
1.260     brouard  7294:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7295:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7296:          continue;
                   7297:        }
1.235     brouard  7298:       
1.241     brouard  7299:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7300:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7301:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7302:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7303:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7304:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7305:       /* k1-1 error should be nres-1*/
1.238     brouard  7306:        for (i=1; i<= nlstate ; i ++) {
                   7307:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7308:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7309:        }
1.288     brouard  7310:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7311:        for (i=1; i<= nlstate ; i ++) {
                   7312:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7313:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7314:        } 
1.260     brouard  7315:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7316:        for (i=1; i<= nlstate ; i ++) {
                   7317:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7318:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7319:        }  
1.265     brouard  7320:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7321:        
                   7322:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7323:         if(cptcoveff ==0){
1.271     brouard  7324:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7325:        }else{
                   7326:          kl=0;
                   7327:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7328:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7329:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7330:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7331:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7332:            vlv= nbcode[Tvaraff[k]][lv];
                   7333:            kl++;
                   7334:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7335:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7336:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7337:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7338:            if(k==cptcoveff){
                   7339:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7340:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7341:            }else{
                   7342:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7343:              kl++;
                   7344:            }
                   7345:          } /* end covariate */
                   7346:        } /* end if no covariate */
                   7347: 
1.296     brouard  7348:        if(prevbcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
1.238     brouard  7349:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7350:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7351:          if(cptcoveff ==0){
1.245     brouard  7352:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7353:          }else{
                   7354:            kl=0;
                   7355:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7356:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7357:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7358:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7359:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7360:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7361:              kl++;
1.238     brouard  7362:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7363:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7364:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7365:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7366:              if(k==cptcoveff){
1.245     brouard  7367:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7368:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7369:              }else{
                   7370:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7371:                kl++;
                   7372:              }
                   7373:            } /* end covariate */
                   7374:          } /* end if no covariate */
1.296     brouard  7375:          if(prevbcast == 1){
1.268     brouard  7376:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7377:            /* k1-1 error should be nres-1*/
                   7378:            for (i=1; i<= nlstate ; i ++) {
                   7379:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7380:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7381:            }
1.271     brouard  7382:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7383:            for (i=1; i<= nlstate ; i ++) {
                   7384:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7385:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7386:            } 
1.276     brouard  7387:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7388:            for (i=1; i<= nlstate ; i ++) {
                   7389:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7390:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7391:            } 
1.274     brouard  7392:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7393:          } /* end if backprojcast */
1.296     brouard  7394:        } /* end if prevbcast */
1.276     brouard  7395:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7396:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7397:       } /* nres */
1.201     brouard  7398:     } /* k1 */
                   7399:   } /* cpt */
1.235     brouard  7400: 
                   7401:   
1.126     brouard  7402:   /*2 eme*/
1.238     brouard  7403:   for (k1=1; k1<= m ; k1 ++){  
                   7404:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7405:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7406:        continue;
                   7407:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7408:       strcpy(gplotlabel,"(");
1.238     brouard  7409:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7410:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7411:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7412:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7413:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7414:        vlv= nbcode[Tvaraff[k]][lv];
                   7415:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7416:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7417:       }
1.237     brouard  7418:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7419:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7420:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7421:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7422:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7423:       }
1.264     brouard  7424:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7425:       fprintf(ficgp,"\n#\n");
1.223     brouard  7426:       if(invalidvarcomb[k1]){
                   7427:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7428:        continue;
                   7429:       }
1.219     brouard  7430:                        
1.241     brouard  7431:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7432:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7433:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7434:        if(vpopbased==0){
1.238     brouard  7435:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7436:        }else
1.238     brouard  7437:          fprintf(ficgp,"\nreplot ");
                   7438:        for (i=1; i<= nlstate+1 ; i ++) {
                   7439:          k=2*i;
1.261     brouard  7440:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7441:          for (j=1; j<= nlstate+1 ; j ++) {
                   7442:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7443:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7444:          }   
                   7445:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7446:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7447:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7448:          for (j=1; j<= nlstate+1 ; j ++) {
                   7449:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7450:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7451:          }   
                   7452:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7453:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7454:          for (j=1; j<= nlstate+1 ; j ++) {
                   7455:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7456:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7457:          }   
                   7458:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7459:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7460:        } /* state */
                   7461:       } /* vpopbased */
1.264     brouard  7462:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7463:     } /* end nres */
                   7464:   } /* k1 end 2 eme*/
                   7465:        
                   7466:        
                   7467:   /*3eme*/
                   7468:   for (k1=1; k1<= m ; k1 ++){
                   7469:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7470:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7471:        continue;
                   7472: 
                   7473:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7474:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7475:        strcpy(gplotlabel,"(");
1.238     brouard  7476:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7477:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7478:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7479:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7480:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7481:          vlv= nbcode[Tvaraff[k]][lv];
                   7482:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7483:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7484:        }
                   7485:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7486:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7487:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7488:        }       
1.264     brouard  7489:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7490:        fprintf(ficgp,"\n#\n");
                   7491:        if(invalidvarcomb[k1]){
                   7492:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7493:          continue;
                   7494:        }
                   7495:                        
                   7496:        /*       k=2+nlstate*(2*cpt-2); */
                   7497:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7498:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7499:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7500:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7501: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7502:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7503:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7504:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7505:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7506:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7507:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7508:                                
1.238     brouard  7509:        */
                   7510:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7511:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7512:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7513:                                
1.238     brouard  7514:        } 
1.261     brouard  7515:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7516:       }
1.264     brouard  7517:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7518:     } /* end nres */
                   7519:   } /* end kl 3eme */
1.126     brouard  7520:   
1.223     brouard  7521:   /* 4eme */
1.201     brouard  7522:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7523:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7524:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7525:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7526:        continue;
1.238     brouard  7527:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7528:        strcpy(gplotlabel,"(");
1.238     brouard  7529:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7530:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7531:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7532:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7533:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7534:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7535:          vlv= nbcode[Tvaraff[k]][lv];
                   7536:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7537:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7538:        }
                   7539:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7540:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7541:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7542:        }       
1.264     brouard  7543:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7544:        fprintf(ficgp,"\n#\n");
                   7545:        if(invalidvarcomb[k1]){
                   7546:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7547:          continue;
1.223     brouard  7548:        }
1.238     brouard  7549:       
1.241     brouard  7550:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7551:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7552:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7553: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7554:        k=3;
                   7555:        for (i=1; i<= nlstate ; i ++){
                   7556:          if(i==1){
                   7557:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7558:          }else{
                   7559:            fprintf(ficgp,", '' ");
                   7560:          }
                   7561:          l=(nlstate+ndeath)*(i-1)+1;
                   7562:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7563:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7564:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7565:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7566:        } /* nlstate */
1.264     brouard  7567:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7568:       } /* end cpt state*/ 
                   7569:     } /* end nres */
                   7570:   } /* end covariate k1 */  
                   7571: 
1.220     brouard  7572: /* 5eme */
1.201     brouard  7573:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7574:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7575:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7576:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7577:        continue;
1.238     brouard  7578:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7579:        strcpy(gplotlabel,"(");
1.238     brouard  7580:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7581:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7582:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7583:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7584:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7585:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7586:          vlv= nbcode[Tvaraff[k]][lv];
                   7587:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7588:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7589:        }
                   7590:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7591:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7592:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7593:        }       
1.264     brouard  7594:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7595:        fprintf(ficgp,"\n#\n");
                   7596:        if(invalidvarcomb[k1]){
                   7597:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7598:          continue;
                   7599:        }
1.227     brouard  7600:       
1.241     brouard  7601:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7602:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7603:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7604: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7605:        k=3;
                   7606:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7607:          if(j==1)
                   7608:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7609:          else
                   7610:            fprintf(ficgp,", '' ");
                   7611:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7612:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7613:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7614:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7615:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7616:        } /* nlstate */
                   7617:        fprintf(ficgp,", '' ");
                   7618:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7619:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7620:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7621:          if(j < nlstate)
                   7622:            fprintf(ficgp,"$%d +",k+l);
                   7623:          else
                   7624:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7625:        }
1.264     brouard  7626:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7627:       } /* end cpt state*/ 
                   7628:     } /* end covariate */  
                   7629:   } /* end nres */
1.227     brouard  7630:   
1.220     brouard  7631: /* 6eme */
1.202     brouard  7632:   /* CV preval stable (period) for each covariate */
1.237     brouard  7633:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7634:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7635:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7636:       continue;
1.255     brouard  7637:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7638:       strcpy(gplotlabel,"(");      
1.288     brouard  7639:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7640:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7641:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7642:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7643:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7644:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7645:        vlv= nbcode[Tvaraff[k]][lv];
                   7646:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7647:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7648:       }
1.237     brouard  7649:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7650:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7651:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7652:       }        
1.264     brouard  7653:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7654:       fprintf(ficgp,"\n#\n");
1.223     brouard  7655:       if(invalidvarcomb[k1]){
1.227     brouard  7656:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7657:        continue;
1.223     brouard  7658:       }
1.227     brouard  7659:       
1.241     brouard  7660:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7661:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7662:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7663: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7664:       k=3; /* Offset */
1.255     brouard  7665:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7666:        if(i==1)
                   7667:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7668:        else
                   7669:          fprintf(ficgp,", '' ");
1.255     brouard  7670:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7671:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7672:        for (j=2; j<= nlstate ; j ++)
                   7673:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7674:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7675:       } /* nlstate */
1.264     brouard  7676:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7677:     } /* end cpt state*/ 
                   7678:   } /* end covariate */  
1.227     brouard  7679:   
                   7680:   
1.220     brouard  7681: /* 7eme */
1.296     brouard  7682:   if(prevbcast == 1){
1.288     brouard  7683:     /* CV backward prevalence  for each covariate */
1.237     brouard  7684:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7685:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7686:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7687:        continue;
1.268     brouard  7688:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7689:        strcpy(gplotlabel,"(");      
1.288     brouard  7690:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7691:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7692:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7693:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7694:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7695:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7696:          vlv= nbcode[Tvaraff[k]][lv];
                   7697:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7698:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7699:        }
1.237     brouard  7700:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7701:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7702:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7703:        }       
1.264     brouard  7704:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7705:        fprintf(ficgp,"\n#\n");
                   7706:        if(invalidvarcomb[k1]){
                   7707:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7708:          continue;
                   7709:        }
                   7710:        
1.241     brouard  7711:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7712:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7713:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7714: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7715:        k=3; /* Offset */
1.268     brouard  7716:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7717:          if(i==1)
                   7718:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7719:          else
                   7720:            fprintf(ficgp,", '' ");
                   7721:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7722:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7723:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7724:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7725:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7726:          /* for (j=2; j<= nlstate ; j ++) */
                   7727:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7728:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7729:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7730:        } /* nlstate */
1.264     brouard  7731:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7732:       } /* end cpt state*/ 
                   7733:     } /* end covariate */  
1.296     brouard  7734:   } /* End if prevbcast */
1.218     brouard  7735:   
1.223     brouard  7736:   /* 8eme */
1.218     brouard  7737:   if(prevfcast==1){
1.288     brouard  7738:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7739:     
1.237     brouard  7740:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7741:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7742:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7743:        continue;
1.211     brouard  7744:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7745:        strcpy(gplotlabel,"(");      
1.288     brouard  7746:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7747:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7748:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7749:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7750:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7751:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7752:          vlv= nbcode[Tvaraff[k]][lv];
                   7753:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7754:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7755:        }
1.237     brouard  7756:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7757:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7758:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7759:        }       
1.264     brouard  7760:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7761:        fprintf(ficgp,"\n#\n");
                   7762:        if(invalidvarcomb[k1]){
                   7763:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7764:          continue;
                   7765:        }
                   7766:        
                   7767:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7768:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7769:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7770:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7771: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7772: 
                   7773:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7774:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7775:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7776:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7777:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7778:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7779:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7780:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7781:          if(i==istart){
1.227     brouard  7782:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7783:          }else{
                   7784:            fprintf(ficgp,",\\\n '' ");
                   7785:          }
                   7786:          if(cptcoveff ==0){ /* No covariate */
                   7787:            ioffset=2; /* Age is in 2 */
                   7788:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7789:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7790:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7791:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7792:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7793:            if(i==nlstate+1){
1.270     brouard  7794:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7795:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7796:              fprintf(ficgp,",\\\n '' ");
                   7797:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7798:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7799:                     offyear,                           \
1.268     brouard  7800:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7801:            }else
1.227     brouard  7802:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7803:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7804:          }else{ /* more than 2 covariates */
1.270     brouard  7805:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7806:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7807:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7808:            iyearc=ioffset-1;
                   7809:            iagec=ioffset;
1.227     brouard  7810:            fprintf(ficgp," u %d:(",ioffset); 
                   7811:            kl=0;
                   7812:            strcpy(gplotcondition,"(");
                   7813:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7814:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7815:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7816:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7817:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7818:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7819:              kl++;
                   7820:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7821:              kl++;
                   7822:              if(k <cptcoveff && cptcoveff>1)
                   7823:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7824:            }
                   7825:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7826:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7827:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7828:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7829:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7830:            if(i==nlstate+1){
1.270     brouard  7831:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7832:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7833:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7834:              fprintf(ficgp," u %d:(",iagec); 
                   7835:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7836:                      iyearc, iagec, offyear,                           \
                   7837:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7838: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7839:            }else{
                   7840:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7841:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7842:            }
                   7843:          } /* end if covariate */
                   7844:        } /* nlstate */
1.264     brouard  7845:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7846:       } /* end cpt state*/
                   7847:     } /* end covariate */
                   7848:   } /* End if prevfcast */
1.227     brouard  7849:   
1.296     brouard  7850:   if(prevbcast==1){
1.268     brouard  7851:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7852:     
                   7853:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7854:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7855:       if(m != 1 && TKresult[nres]!= k1)
                   7856:        continue;
                   7857:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7858:        strcpy(gplotlabel,"(");      
                   7859:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7860:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7861:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7862:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7863:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7864:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7865:          vlv= nbcode[Tvaraff[k]][lv];
                   7866:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7867:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7868:        }
                   7869:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7870:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7871:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7872:        }       
                   7873:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7874:        fprintf(ficgp,"\n#\n");
                   7875:        if(invalidvarcomb[k1]){
                   7876:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7877:          continue;
                   7878:        }
                   7879:        
                   7880:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7881:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7882:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7883:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7884: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7885: 
                   7886:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7887:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7888:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7889:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7890:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7891:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7892:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7893:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7894:          if(i==istart){
                   7895:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7896:          }else{
                   7897:            fprintf(ficgp,",\\\n '' ");
                   7898:          }
                   7899:          if(cptcoveff ==0){ /* No covariate */
                   7900:            ioffset=2; /* Age is in 2 */
                   7901:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7902:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7903:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7904:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7905:            fprintf(ficgp," u %d:(", ioffset); 
                   7906:            if(i==nlstate+1){
1.270     brouard  7907:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7908:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7909:              fprintf(ficgp,",\\\n '' ");
                   7910:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7911:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7912:                     offbyear,                          \
                   7913:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7914:            }else
                   7915:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7916:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7917:          }else{ /* more than 2 covariates */
1.270     brouard  7918:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7919:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7920:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7921:            iyearc=ioffset-1;
                   7922:            iagec=ioffset;
1.268     brouard  7923:            fprintf(ficgp," u %d:(",ioffset); 
                   7924:            kl=0;
                   7925:            strcpy(gplotcondition,"(");
                   7926:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7927:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7928:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7929:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7930:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7931:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7932:              kl++;
                   7933:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7934:              kl++;
                   7935:              if(k <cptcoveff && cptcoveff>1)
                   7936:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7937:            }
                   7938:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7939:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7940:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7941:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7942:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7943:            if(i==nlstate+1){
1.270     brouard  7944:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7945:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7946:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7947:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7948:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7949:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7950:                      iyearc,iagec,offbyear,                            \
                   7951:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7952: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7953:            }else{
                   7954:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7955:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7956:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7957:            }
                   7958:          } /* end if covariate */
                   7959:        } /* nlstate */
                   7960:        fprintf(ficgp,"\nset out; unset label;\n");
                   7961:       } /* end cpt state*/
                   7962:     } /* end covariate */
1.296     brouard  7963:   } /* End if prevbcast */
1.268     brouard  7964:   
1.227     brouard  7965:   
1.238     brouard  7966:   /* 9eme writing MLE parameters */
                   7967:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7968:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7969:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7970:     for(k=1; k <=(nlstate+ndeath); k++){
                   7971:       if (k != i) {
1.227     brouard  7972:        fprintf(ficgp,"#   current state %d\n",k);
                   7973:        for(j=1; j <=ncovmodel; j++){
                   7974:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   7975:          jk++; 
                   7976:        }
                   7977:        fprintf(ficgp,"\n");
1.126     brouard  7978:       }
                   7979:     }
1.223     brouard  7980:   }
1.187     brouard  7981:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  7982:   
1.145     brouard  7983:   /*goto avoid;*/
1.238     brouard  7984:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   7985:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  7986:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   7987:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   7988:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   7989:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   7990:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7991:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7992:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7993:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   7994:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   7995:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   7996:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   7997:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   7998:   fprintf(ficgp,"#\n");
1.223     brouard  7999:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  8000:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  8001:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  8002:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  8003:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   8004:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  8005:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  8006:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  8007:        continue;
1.264     brouard  8008:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   8009:       strcpy(gplotlabel,"(");
1.276     brouard  8010:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  8011:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8012:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8013:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8014:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8015:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8016:        vlv= nbcode[Tvaraff[k]][lv];
                   8017:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   8018:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   8019:       }
1.237     brouard  8020:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8021:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  8022:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  8023:       }        
1.264     brouard  8024:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  8025:       fprintf(ficgp,"\n#\n");
1.264     brouard  8026:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  8027:       fprintf(ficgp,"\nset key outside ");
                   8028:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   8029:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  8030:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   8031:       if (ng==1){
                   8032:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   8033:        fprintf(ficgp,"\nunset log y");
                   8034:       }else if (ng==2){
                   8035:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   8036:        fprintf(ficgp,"\nset log y");
                   8037:       }else if (ng==3){
                   8038:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   8039:        fprintf(ficgp,"\nset log y");
                   8040:       }else
                   8041:        fprintf(ficgp,"\nunset title ");
                   8042:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   8043:       i=1;
                   8044:       for(k2=1; k2<=nlstate; k2++) {
                   8045:        k3=i;
                   8046:        for(k=1; k<=(nlstate+ndeath); k++) {
                   8047:          if (k != k2){
                   8048:            switch( ng) {
                   8049:            case 1:
                   8050:              if(nagesqr==0)
                   8051:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   8052:              else /* nagesqr =1 */
                   8053:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8054:              break;
                   8055:            case 2: /* ng=2 */
                   8056:              if(nagesqr==0)
                   8057:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   8058:              else /* nagesqr =1 */
                   8059:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8060:              break;
                   8061:            case 3:
                   8062:              if(nagesqr==0)
                   8063:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   8064:              else /* nagesqr =1 */
                   8065:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   8066:              break;
                   8067:            }
                   8068:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  8069:            ijp=1; /* product no age */
                   8070:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   8071:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  8072:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  8073:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8074:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   8075:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8076:                    if(DummyV[j]==0){
                   8077:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   8078:                    }else{ /* quantitative */
                   8079:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   8080:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8081:                    }
                   8082:                    ij++;
1.237     brouard  8083:                  }
1.268     brouard  8084:                } 
                   8085:              }else if(cptcovprod >0){
                   8086:                if(j==Tprod[ijp]) { /* */ 
                   8087:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   8088:                  if(ijp <=cptcovprod) { /* Product */
                   8089:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   8090:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   8091:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   8092:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   8093:                      }else{ /* Vn is dummy and Vm is quanti */
                   8094:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   8095:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8096:                      }
                   8097:                    }else{ /* Vn*Vm Vn is quanti */
                   8098:                      if(DummyV[Tvard[ijp][2]]==0){
                   8099:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   8100:                      }else{ /* Both quanti */
                   8101:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8102:                      }
1.237     brouard  8103:                    }
1.268     brouard  8104:                    ijp++;
1.237     brouard  8105:                  }
1.268     brouard  8106:                } /* end Tprod */
1.237     brouard  8107:              } else{  /* simple covariate */
1.264     brouard  8108:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  8109:                if(Dummy[j]==0){
                   8110:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   8111:                }else{ /* quantitative */
                   8112:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  8113:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  8114:                }
1.237     brouard  8115:              } /* end simple */
                   8116:            } /* end j */
1.223     brouard  8117:          }else{
                   8118:            i=i-ncovmodel;
                   8119:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8120:              fprintf(ficgp," (1.");
                   8121:          }
1.227     brouard  8122:          
1.223     brouard  8123:          if(ng != 1){
                   8124:            fprintf(ficgp,")/(1");
1.227     brouard  8125:            
1.264     brouard  8126:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8127:              if(nagesqr==0)
1.264     brouard  8128:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8129:              else /* nagesqr =1 */
1.264     brouard  8130:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8131:               
1.223     brouard  8132:              ij=1;
                   8133:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8134:                 if(cptcovage >0){ 
                   8135:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8136:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8137:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8138:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8139:                       ij++;
                   8140:                     }
                   8141:                   }
                   8142:                 }else
                   8143:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8144:              }
                   8145:              fprintf(ficgp,")");
                   8146:            }
                   8147:            fprintf(ficgp,")");
                   8148:            if(ng ==2)
1.276     brouard  8149:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8150:            else /* ng= 3 */
1.276     brouard  8151:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8152:          }else{ /* end ng <> 1 */
                   8153:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8154:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8155:          }
                   8156:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8157:            fprintf(ficgp,",");
                   8158:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8159:            fprintf(ficgp,",");
                   8160:          i=i+ncovmodel;
                   8161:        } /* end k */
                   8162:       } /* end k2 */
1.276     brouard  8163:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8164:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8165:     } /* end k1 */
1.223     brouard  8166:   } /* end ng */
                   8167:   /* avoid: */
                   8168:   fflush(ficgp); 
1.126     brouard  8169: }  /* end gnuplot */
                   8170: 
                   8171: 
                   8172: /*************** Moving average **************/
1.219     brouard  8173: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8174:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8175:    
1.222     brouard  8176:    int i, cpt, cptcod;
                   8177:    int modcovmax =1;
                   8178:    int mobilavrange, mob;
                   8179:    int iage=0;
1.288     brouard  8180:    int firstA1=0, firstA2=0;
1.222     brouard  8181: 
1.266     brouard  8182:    double sum=0., sumr=0.;
1.222     brouard  8183:    double age;
1.266     brouard  8184:    double *sumnewp, *sumnewm, *sumnewmr;
                   8185:    double *agemingood, *agemaxgood; 
                   8186:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8187:   
                   8188:   
1.278     brouard  8189:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8190:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8191: 
                   8192:    sumnewp = vector(1,ncovcombmax);
                   8193:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8194:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8195:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8196:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8197:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8198:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8199: 
                   8200:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8201:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8202:      sumnewp[cptcod]=0.;
1.266     brouard  8203:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8204:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8205:    }
                   8206:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8207:   
1.266     brouard  8208:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8209:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8210:      else mobilavrange=mobilav;
                   8211:      for (age=bage; age<=fage; age++)
                   8212:        for (i=1; i<=nlstate;i++)
                   8213:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8214:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8215:      /* We keep the original values on the extreme ages bage, fage and for 
                   8216:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8217:        we use a 5 terms etc. until the borders are no more concerned. 
                   8218:      */ 
                   8219:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8220:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8221:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8222:           sumnewm[cptcod]=0.;
                   8223:           for (i=1; i<=nlstate;i++){
1.222     brouard  8224:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8225:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8226:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8227:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8228:             }
                   8229:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8230:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8231:           } /* end i */
                   8232:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8233:         } /* end cptcod */
1.222     brouard  8234:        }/* end age */
                   8235:      }/* end mob */
1.266     brouard  8236:    }else{
                   8237:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8238:      return -1;
1.266     brouard  8239:    }
                   8240: 
                   8241:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8242:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8243:      if(invalidvarcomb[cptcod]){
                   8244:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8245:        continue;
                   8246:      }
1.219     brouard  8247: 
1.266     brouard  8248:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8249:        sumnewm[cptcod]=0.;
                   8250:        sumnewmr[cptcod]=0.;
                   8251:        for (i=1; i<=nlstate;i++){
                   8252:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8253:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8254:        }
                   8255:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8256:         agemingoodr[cptcod]=age;
                   8257:        }
                   8258:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8259:           agemingood[cptcod]=age;
                   8260:        }
                   8261:      } /* age */
                   8262:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8263:        sumnewm[cptcod]=0.;
1.266     brouard  8264:        sumnewmr[cptcod]=0.;
1.222     brouard  8265:        for (i=1; i<=nlstate;i++){
                   8266:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8267:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8268:        }
                   8269:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8270:         agemaxgoodr[cptcod]=age;
1.222     brouard  8271:        }
                   8272:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8273:         agemaxgood[cptcod]=age;
                   8274:        }
                   8275:      } /* age */
                   8276:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8277:      /* but they will change */
1.288     brouard  8278:      firstA1=0;firstA2=0;
1.266     brouard  8279:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8280:        sumnewm[cptcod]=0.;
                   8281:        sumnewmr[cptcod]=0.;
                   8282:        for (i=1; i<=nlstate;i++){
                   8283:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8284:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8285:        }
                   8286:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8287:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8288:           agemaxgoodr[cptcod]=age;  /* age min */
                   8289:           for (i=1; i<=nlstate;i++)
                   8290:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8291:         }else{ /* bad we change the value with the values of good ages */
                   8292:           for (i=1; i<=nlstate;i++){
                   8293:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8294:           } /* i */
                   8295:         } /* end bad */
                   8296:        }else{
                   8297:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8298:           agemaxgood[cptcod]=age;
                   8299:         }else{ /* bad we change the value with the values of good ages */
                   8300:           for (i=1; i<=nlstate;i++){
                   8301:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8302:           } /* i */
                   8303:         } /* end bad */
                   8304:        }/* end else */
                   8305:        sum=0.;sumr=0.;
                   8306:        for (i=1; i<=nlstate;i++){
                   8307:         sum+=mobaverage[(int)age][i][cptcod];
                   8308:         sumr+=probs[(int)age][i][cptcod];
                   8309:        }
                   8310:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8311:         if(!firstA1){
                   8312:           firstA1=1;
                   8313:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8314:         }
                   8315:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8316:        } /* end bad */
                   8317:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8318:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8319:         if(!firstA2){
                   8320:           firstA2=1;
                   8321:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8322:         }
                   8323:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8324:        } /* end bad */
                   8325:      }/* age */
1.266     brouard  8326: 
                   8327:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8328:        sumnewm[cptcod]=0.;
1.266     brouard  8329:        sumnewmr[cptcod]=0.;
1.222     brouard  8330:        for (i=1; i<=nlstate;i++){
                   8331:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8332:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8333:        } 
                   8334:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8335:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8336:           agemingoodr[cptcod]=age;
                   8337:           for (i=1; i<=nlstate;i++)
                   8338:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8339:         }else{ /* bad we change the value with the values of good ages */
                   8340:           for (i=1; i<=nlstate;i++){
                   8341:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8342:           } /* i */
                   8343:         } /* end bad */
                   8344:        }else{
                   8345:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8346:           agemingood[cptcod]=age;
                   8347:         }else{ /* bad */
                   8348:           for (i=1; i<=nlstate;i++){
                   8349:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8350:           } /* i */
                   8351:         } /* end bad */
                   8352:        }/* end else */
                   8353:        sum=0.;sumr=0.;
                   8354:        for (i=1; i<=nlstate;i++){
                   8355:         sum+=mobaverage[(int)age][i][cptcod];
                   8356:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8357:        }
1.266     brouard  8358:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8359:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8360:        } /* end bad */
                   8361:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8362:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8363:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8364:        } /* end bad */
                   8365:      }/* age */
1.266     brouard  8366: 
1.222     brouard  8367:                
                   8368:      for (age=bage; age<=fage; age++){
1.235     brouard  8369:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8370:        sumnewp[cptcod]=0.;
                   8371:        sumnewm[cptcod]=0.;
                   8372:        for (i=1; i<=nlstate;i++){
                   8373:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8374:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8375:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8376:        }
                   8377:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8378:      }
                   8379:      /* printf("\n"); */
                   8380:      /* } */
1.266     brouard  8381: 
1.222     brouard  8382:      /* brutal averaging */
1.266     brouard  8383:      /* for (i=1; i<=nlstate;i++){ */
                   8384:      /*   for (age=1; age<=bage; age++){ */
                   8385:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8386:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8387:      /*   }     */
                   8388:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8389:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8390:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8391:      /*   } */
                   8392:      /* } /\* end i status *\/ */
                   8393:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8394:      /*   for (age=1; age<=AGESUP; age++){ */
                   8395:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8396:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8397:      /*   } */
                   8398:      /* } */
1.222     brouard  8399:    }/* end cptcod */
1.266     brouard  8400:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8401:    free_vector(agemaxgood,1, ncovcombmax);
                   8402:    free_vector(agemingood,1, ncovcombmax);
                   8403:    free_vector(agemingoodr,1, ncovcombmax);
                   8404:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8405:    free_vector(sumnewm,1, ncovcombmax);
                   8406:    free_vector(sumnewp,1, ncovcombmax);
                   8407:    return 0;
                   8408:  }/* End movingaverage */
1.218     brouard  8409:  
1.126     brouard  8410: 
1.296     brouard  8411:  
1.126     brouard  8412: /************** Forecasting ******************/
1.296     brouard  8413: /* void prevforecast(char fileres[], double dateintmean, double anprojd, double mprojd, double jprojd, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anprojf, double p[], int cptcoveff)*/
                   8414: void prevforecast(char fileres[], double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8415:   /* dateintemean, mean date of interviews
                   8416:      dateprojd, year, month, day of starting projection 
                   8417:      dateprojf date of end of projection;year of end of projection (same day and month as proj1).
1.126     brouard  8418:      agemin, agemax range of age
                   8419:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8420:   */
1.296     brouard  8421:   /* double anprojd, mprojd, jprojd; */
                   8422:   /* double anprojf, mprojf, jprojf; */
1.267     brouard  8423:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8424:   double agec; /* generic age */
1.296     brouard  8425:   double agelim, ppij, yp,yp1,yp2;
1.126     brouard  8426:   double *popeffectif,*popcount;
                   8427:   double ***p3mat;
1.218     brouard  8428:   /* double ***mobaverage; */
1.126     brouard  8429:   char fileresf[FILENAMELENGTH];
                   8430: 
                   8431:   agelim=AGESUP;
1.211     brouard  8432:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8433:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8434:      We still use firstpass and lastpass as another selection.
                   8435:   */
1.214     brouard  8436:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8437:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8438:  
1.201     brouard  8439:   strcpy(fileresf,"F_"); 
                   8440:   strcat(fileresf,fileresu);
1.126     brouard  8441:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8442:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8443:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8444:   }
1.235     brouard  8445:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8446:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8447: 
1.225     brouard  8448:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8449: 
                   8450: 
                   8451:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8452:   if (stepm<=12) stepsize=1;
                   8453:   if(estepm < stepm){
                   8454:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8455:   }
1.270     brouard  8456:   else{
                   8457:     hstepm=estepm;   
                   8458:   }
                   8459:   if(estepm > stepm){ /* Yes every two year */
                   8460:     stepsize=2;
                   8461:   }
1.296     brouard  8462:   hstepm=hstepm/stepm;
1.126     brouard  8463: 
1.296     brouard  8464:   
                   8465:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8466:   /*                              fractional in yp1 *\/ */
                   8467:   /* aintmean=yp; */
                   8468:   /* yp2=modf((yp1*12),&yp); */
                   8469:   /* mintmean=yp; */
                   8470:   /* yp1=modf((yp2*30.5),&yp); */
                   8471:   /* jintmean=yp; */
                   8472:   /* if(jintmean==0) jintmean=1; */
                   8473:   /* if(mintmean==0) mintmean=1; */
1.126     brouard  8474: 
1.296     brouard  8475: 
                   8476:   /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */
                   8477:   /* date2dmy(dateprojd,&jprojd, &mprojd, &anprojd); */
                   8478:   /* date2dmy(dateprojf,&jprojf, &mprojf, &anprojf); */
1.227     brouard  8479:   i1=pow(2,cptcoveff);
1.126     brouard  8480:   if (cptcovn < 1){i1=1;}
                   8481:   
1.296     brouard  8482:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2); 
1.126     brouard  8483:   
                   8484:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8485:   
1.126     brouard  8486: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8487:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8488:   for(k=1; k<=i1;k++){
1.253     brouard  8489:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8490:       continue;
1.227     brouard  8491:     if(invalidvarcomb[k]){
                   8492:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8493:       continue;
                   8494:     }
                   8495:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8496:     for(j=1;j<=cptcoveff;j++) {
                   8497:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8498:     }
1.235     brouard  8499:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8500:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8501:     }
1.227     brouard  8502:     fprintf(ficresf," yearproj age");
                   8503:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8504:       for(i=1; i<=nlstate;i++)               
                   8505:        fprintf(ficresf," p%d%d",i,j);
                   8506:       fprintf(ficresf," wp.%d",j);
                   8507:     }
1.296     brouard  8508:     for (yearp=0; yearp<=(anprojf-anprojd);yearp +=stepsize) {
1.227     brouard  8509:       fprintf(ficresf,"\n");
1.296     brouard  8510:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jprojd,mprojd,anprojd+yearp);   
1.270     brouard  8511:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8512:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8513:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8514:        nhstepm = nhstepm/hstepm; 
                   8515:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8516:        oldm=oldms;savm=savms;
1.268     brouard  8517:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8518:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8519:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8520:        for (h=0; h<=nhstepm; h++){
                   8521:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8522:            break;
                   8523:          }
                   8524:        }
                   8525:        fprintf(ficresf,"\n");
                   8526:        for(j=1;j<=cptcoveff;j++) 
                   8527:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8528:        fprintf(ficresf,"%.f %.f ",anprojd+yearp,agec+h*hstepm/YEARM*stepm);
1.268     brouard  8529:        
                   8530:        for(j=1; j<=nlstate+ndeath;j++) {
                   8531:          ppij=0.;
                   8532:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8533:            if (mobilav>=1)
                   8534:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8535:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8536:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8537:            }
1.268     brouard  8538:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8539:          } /* end i */
                   8540:          fprintf(ficresf," %.3f", ppij);
                   8541:        }/* end j */
1.227     brouard  8542:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8543:       } /* end agec */
1.266     brouard  8544:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8545:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8546:     } /* end yearp */
                   8547:   } /* end  k */
1.219     brouard  8548:        
1.126     brouard  8549:   fclose(ficresf);
1.215     brouard  8550:   printf("End of Computing forecasting \n");
                   8551:   fprintf(ficlog,"End of Computing forecasting\n");
                   8552: 
1.126     brouard  8553: }
                   8554: 
1.269     brouard  8555: /************** Back Forecasting ******************/
1.296     brouard  8556:  /* void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
                   8557:  void prevbackforecast(char fileres[], double ***prevacurrent, double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8558:   /* back1, year, month, day of starting backprojection
1.267     brouard  8559:      agemin, agemax range of age
                   8560:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8561:      anback2 year of end of backprojection (same day and month as back1).
                   8562:      prevacurrent and prev are prevalences.
1.267     brouard  8563:   */
                   8564:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8565:   double agec; /* generic age */
1.302     brouard  8566:   double agelim, ppij, ppi, yp,yp1,yp2; /* ,jintmean,mintmean,aintmean;*/
1.267     brouard  8567:   double *popeffectif,*popcount;
                   8568:   double ***p3mat;
                   8569:   /* double ***mobaverage; */
                   8570:   char fileresfb[FILENAMELENGTH];
                   8571:  
1.268     brouard  8572:   agelim=AGEINF;
1.267     brouard  8573:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8574:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8575:      We still use firstpass and lastpass as another selection.
                   8576:   */
                   8577:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8578:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8579: 
                   8580:   /*Do we need to compute prevalence again?*/
                   8581: 
                   8582:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8583:   
                   8584:   strcpy(fileresfb,"FB_");
                   8585:   strcat(fileresfb,fileresu);
                   8586:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8587:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8588:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8589:   }
                   8590:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8591:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8592:   
                   8593:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8594:   
                   8595:    
                   8596:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8597:   if (stepm<=12) stepsize=1;
                   8598:   if(estepm < stepm){
                   8599:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8600:   }
1.270     brouard  8601:   else{
                   8602:     hstepm=estepm;   
                   8603:   }
                   8604:   if(estepm >= stepm){ /* Yes every two year */
                   8605:     stepsize=2;
                   8606:   }
1.267     brouard  8607:   
                   8608:   hstepm=hstepm/stepm;
1.296     brouard  8609:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8610:   /*                              fractional in yp1 *\/ */
                   8611:   /* aintmean=yp; */
                   8612:   /* yp2=modf((yp1*12),&yp); */
                   8613:   /* mintmean=yp; */
                   8614:   /* yp1=modf((yp2*30.5),&yp); */
                   8615:   /* jintmean=yp; */
                   8616:   /* if(jintmean==0) jintmean=1; */
                   8617:   /* if(mintmean==0) jintmean=1; */
1.267     brouard  8618:   
                   8619:   i1=pow(2,cptcoveff);
                   8620:   if (cptcovn < 1){i1=1;}
                   8621:   
1.296     brouard  8622:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
                   8623:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8624:   
                   8625:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8626:   
                   8627:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8628:   for(k=1; k<=i1;k++){
                   8629:     if(i1 != 1 && TKresult[nres]!= k)
                   8630:       continue;
                   8631:     if(invalidvarcomb[k]){
                   8632:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8633:       continue;
                   8634:     }
1.268     brouard  8635:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8636:     for(j=1;j<=cptcoveff;j++) {
                   8637:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8638:     }
                   8639:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8640:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8641:     }
                   8642:     fprintf(ficresfb," yearbproj age");
                   8643:     for(j=1; j<=nlstate+ndeath;j++){
                   8644:       for(i=1; i<=nlstate;i++)
1.268     brouard  8645:        fprintf(ficresfb," b%d%d",i,j);
                   8646:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8647:     }
1.296     brouard  8648:     for (yearp=0; yearp>=(anbackf-anbackd);yearp -=stepsize) {
1.267     brouard  8649:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8650:       fprintf(ficresfb,"\n");
1.296     brouard  8651:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jbackd,mbackd,anbackd+yearp);
1.273     brouard  8652:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8653:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8654:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8655:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8656:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8657:        nhstepm = nhstepm/hstepm;
                   8658:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8659:        oldm=oldms;savm=savms;
1.268     brouard  8660:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8661:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8662:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8663:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8664:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8665:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8666:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8667:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8668:            break;
                   8669:          }
                   8670:        }
                   8671:        fprintf(ficresfb,"\n");
                   8672:        for(j=1;j<=cptcoveff;j++)
                   8673:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8674:        fprintf(ficresfb,"%.f %.f ",anbackd+yearp,agec-h*hstepm/YEARM*stepm);
1.268     brouard  8675:        for(i=1; i<=nlstate+ndeath;i++) {
                   8676:          ppij=0.;ppi=0.;
                   8677:          for(j=1; j<=nlstate;j++) {
                   8678:            /* if (mobilav==1) */
1.269     brouard  8679:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8680:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8681:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8682:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8683:              /* else { */
                   8684:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8685:              /* } */
1.268     brouard  8686:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8687:          } /* end j */
                   8688:          if(ppi <0.99){
                   8689:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8690:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8691:          }
                   8692:          fprintf(ficresfb," %.3f", ppij);
                   8693:        }/* end j */
1.267     brouard  8694:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8695:       } /* end agec */
                   8696:     } /* end yearp */
                   8697:   } /* end k */
1.217     brouard  8698:   
1.267     brouard  8699:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8700:   
1.267     brouard  8701:   fclose(ficresfb);
                   8702:   printf("End of Computing Back forecasting \n");
                   8703:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8704:        
1.267     brouard  8705: }
1.217     brouard  8706: 
1.269     brouard  8707: /* Variance of prevalence limit: varprlim */
                   8708:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8709:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8710:  
                   8711:    char fileresvpl[FILENAMELENGTH];  
                   8712:    FILE *ficresvpl;
                   8713:    double **oldm, **savm;
                   8714:    double **varpl; /* Variances of prevalence limits by age */   
                   8715:    int i1, k, nres, j ;
                   8716:    
                   8717:     strcpy(fileresvpl,"VPL_");
                   8718:     strcat(fileresvpl,fileresu);
                   8719:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8720:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8721:       exit(0);
                   8722:     }
1.288     brouard  8723:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8724:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8725:     
                   8726:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8727:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8728:     
                   8729:     i1=pow(2,cptcoveff);
                   8730:     if (cptcovn < 1){i1=1;}
                   8731: 
                   8732:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8733:     for(k=1; k<=i1;k++){
                   8734:       if(i1 != 1 && TKresult[nres]!= k)
                   8735:        continue;
                   8736:       fprintf(ficresvpl,"\n#****** ");
                   8737:       printf("\n#****** ");
                   8738:       fprintf(ficlog,"\n#****** ");
                   8739:       for(j=1;j<=cptcoveff;j++) {
                   8740:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8741:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8742:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8743:       }
                   8744:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8745:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8746:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8747:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8748:       }        
                   8749:       fprintf(ficresvpl,"******\n");
                   8750:       printf("******\n");
                   8751:       fprintf(ficlog,"******\n");
                   8752:       
                   8753:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8754:       oldm=oldms;savm=savms;
                   8755:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8756:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8757:       /*}*/
                   8758:     }
                   8759:     
                   8760:     fclose(ficresvpl);
1.288     brouard  8761:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   8762:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  8763: 
                   8764:  }
                   8765: /* Variance of back prevalence: varbprlim */
                   8766:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8767:       /*------- Variance of back (stable) prevalence------*/
                   8768: 
                   8769:    char fileresvbl[FILENAMELENGTH];  
                   8770:    FILE  *ficresvbl;
                   8771: 
                   8772:    double **oldm, **savm;
                   8773:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8774:    int i1, k, nres, j ;
                   8775: 
                   8776:    strcpy(fileresvbl,"VBL_");
                   8777:    strcat(fileresvbl,fileresu);
                   8778:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8779:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8780:      exit(0);
                   8781:    }
                   8782:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8783:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8784:    
                   8785:    
                   8786:    i1=pow(2,cptcoveff);
                   8787:    if (cptcovn < 1){i1=1;}
                   8788:    
                   8789:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8790:      for(k=1; k<=i1;k++){
                   8791:        if(i1 != 1 && TKresult[nres]!= k)
                   8792:         continue;
                   8793:        fprintf(ficresvbl,"\n#****** ");
                   8794:        printf("\n#****** ");
                   8795:        fprintf(ficlog,"\n#****** ");
                   8796:        for(j=1;j<=cptcoveff;j++) {
                   8797:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8798:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8799:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8800:        }
                   8801:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8802:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8803:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8804:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8805:        }
                   8806:        fprintf(ficresvbl,"******\n");
                   8807:        printf("******\n");
                   8808:        fprintf(ficlog,"******\n");
                   8809:        
                   8810:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8811:        oldm=oldms;savm=savms;
                   8812:        
                   8813:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8814:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8815:        /*}*/
                   8816:      }
                   8817:    
                   8818:    fclose(ficresvbl);
                   8819:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8820:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8821: 
                   8822:  } /* End of varbprlim */
                   8823: 
1.126     brouard  8824: /************** Forecasting *****not tested NB*************/
1.227     brouard  8825: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8826:   
1.227     brouard  8827: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8828: /*   int *popage; */
                   8829: /*   double calagedatem, agelim, kk1, kk2; */
                   8830: /*   double *popeffectif,*popcount; */
                   8831: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8832: /*   /\* double ***mobaverage; *\/ */
                   8833: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8834: 
1.227     brouard  8835: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8836: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8837: /*   agelim=AGESUP; */
                   8838: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8839:   
1.227     brouard  8840: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8841:   
                   8842:   
1.227     brouard  8843: /*   strcpy(filerespop,"POP_");  */
                   8844: /*   strcat(filerespop,fileresu); */
                   8845: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8846: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8847: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8848: /*   } */
                   8849: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8850: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8851: 
1.227     brouard  8852: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8853: 
1.227     brouard  8854: /*   /\* if (mobilav!=0) { *\/ */
                   8855: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8856: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8857: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8858: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8859: /*   /\*   } *\/ */
                   8860: /*   /\* } *\/ */
1.126     brouard  8861: 
1.227     brouard  8862: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8863: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8864:   
1.227     brouard  8865: /*   agelim=AGESUP; */
1.126     brouard  8866:   
1.227     brouard  8867: /*   hstepm=1; */
                   8868: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8869:        
1.227     brouard  8870: /*   if (popforecast==1) { */
                   8871: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8872: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8873: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8874: /*     }  */
                   8875: /*     popage=ivector(0,AGESUP); */
                   8876: /*     popeffectif=vector(0,AGESUP); */
                   8877: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8878:     
1.227     brouard  8879: /*     i=1;    */
                   8880: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8881:     
1.227     brouard  8882: /*     imx=i; */
                   8883: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8884: /*   } */
1.218     brouard  8885:   
1.227     brouard  8886: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8887: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8888: /*       k=k+1; */
                   8889: /*       fprintf(ficrespop,"\n#******"); */
                   8890: /*       for(j=1;j<=cptcoveff;j++) { */
                   8891: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8892: /*       } */
                   8893: /*       fprintf(ficrespop,"******\n"); */
                   8894: /*       fprintf(ficrespop,"# Age"); */
                   8895: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8896: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8897:       
1.227     brouard  8898: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8899: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8900:        
1.227     brouard  8901: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8902: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8903: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8904:          
1.227     brouard  8905: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8906: /*       oldm=oldms;savm=savms; */
                   8907: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8908:          
1.227     brouard  8909: /*       for (h=0; h<=nhstepm; h++){ */
                   8910: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8911: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8912: /*         }  */
                   8913: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8914: /*           kk1=0.;kk2=0; */
                   8915: /*           for(i=1; i<=nlstate;i++) {               */
                   8916: /*             if (mobilav==1)  */
                   8917: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8918: /*             else { */
                   8919: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8920: /*             } */
                   8921: /*           } */
                   8922: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8923: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8924: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8925: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8926: /*           } */
                   8927: /*         } */
                   8928: /*         for(i=1; i<=nlstate;i++){ */
                   8929: /*           kk1=0.; */
                   8930: /*           for(j=1; j<=nlstate;j++){ */
                   8931: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8932: /*           } */
                   8933: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8934: /*         } */
1.218     brouard  8935:            
1.227     brouard  8936: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8937: /*           for(j=1; j<=nlstate;j++)  */
                   8938: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8939: /*       } */
                   8940: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8941: /*     } */
                   8942: /*       } */
1.218     brouard  8943:       
1.227     brouard  8944: /*       /\******\/ */
1.218     brouard  8945:       
1.227     brouard  8946: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8947: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8948: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8949: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8950: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8951:          
1.227     brouard  8952: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8953: /*       oldm=oldms;savm=savms; */
                   8954: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8955: /*       for (h=0; h<=nhstepm; h++){ */
                   8956: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8957: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8958: /*         }  */
                   8959: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8960: /*           kk1=0.;kk2=0; */
                   8961: /*           for(i=1; i<=nlstate;i++) {               */
                   8962: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8963: /*           } */
                   8964: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8965: /*         } */
                   8966: /*       } */
                   8967: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8968: /*     } */
                   8969: /*       } */
                   8970: /*     }  */
                   8971: /*   } */
1.218     brouard  8972:   
1.227     brouard  8973: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  8974:   
1.227     brouard  8975: /*   if (popforecast==1) { */
                   8976: /*     free_ivector(popage,0,AGESUP); */
                   8977: /*     free_vector(popeffectif,0,AGESUP); */
                   8978: /*     free_vector(popcount,0,AGESUP); */
                   8979: /*   } */
                   8980: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8981: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8982: /*   fclose(ficrespop); */
                   8983: /* } /\* End of popforecast *\/ */
1.218     brouard  8984:  
1.126     brouard  8985: int fileappend(FILE *fichier, char *optionfich)
                   8986: {
                   8987:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   8988:     printf("Problem with file: %s\n", optionfich);
                   8989:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   8990:     return (0);
                   8991:   }
                   8992:   fflush(fichier);
                   8993:   return (1);
                   8994: }
                   8995: 
                   8996: 
                   8997: /**************** function prwizard **********************/
                   8998: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   8999: {
                   9000: 
                   9001:   /* Wizard to print covariance matrix template */
                   9002: 
1.164     brouard  9003:   char ca[32], cb[32];
                   9004:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  9005:   int numlinepar;
                   9006: 
                   9007:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9008:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9009:   for(i=1; i <=nlstate; i++){
                   9010:     jj=0;
                   9011:     for(j=1; j <=nlstate+ndeath; j++){
                   9012:       if(j==i) continue;
                   9013:       jj++;
                   9014:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   9015:       printf("%1d%1d",i,j);
                   9016:       fprintf(ficparo,"%1d%1d",i,j);
                   9017:       for(k=1; k<=ncovmodel;k++){
                   9018:        /*        printf(" %lf",param[i][j][k]); */
                   9019:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   9020:        printf(" 0.");
                   9021:        fprintf(ficparo," 0.");
                   9022:       }
                   9023:       printf("\n");
                   9024:       fprintf(ficparo,"\n");
                   9025:     }
                   9026:   }
                   9027:   printf("# Scales (for hessian or gradient estimation)\n");
                   9028:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   9029:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   9030:   for(i=1; i <=nlstate; i++){
                   9031:     jj=0;
                   9032:     for(j=1; j <=nlstate+ndeath; j++){
                   9033:       if(j==i) continue;
                   9034:       jj++;
                   9035:       fprintf(ficparo,"%1d%1d",i,j);
                   9036:       printf("%1d%1d",i,j);
                   9037:       fflush(stdout);
                   9038:       for(k=1; k<=ncovmodel;k++){
                   9039:        /*      printf(" %le",delti3[i][j][k]); */
                   9040:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   9041:        printf(" 0.");
                   9042:        fprintf(ficparo," 0.");
                   9043:       }
                   9044:       numlinepar++;
                   9045:       printf("\n");
                   9046:       fprintf(ficparo,"\n");
                   9047:     }
                   9048:   }
                   9049:   printf("# Covariance matrix\n");
                   9050: /* # 121 Var(a12)\n\ */
                   9051: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9052: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   9053: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   9054: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   9055: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   9056: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   9057: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   9058:   fflush(stdout);
                   9059:   fprintf(ficparo,"# Covariance matrix\n");
                   9060:   /* # 121 Var(a12)\n\ */
                   9061:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9062:   /* #   ...\n\ */
                   9063:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   9064:   
                   9065:   for(itimes=1;itimes<=2;itimes++){
                   9066:     jj=0;
                   9067:     for(i=1; i <=nlstate; i++){
                   9068:       for(j=1; j <=nlstate+ndeath; j++){
                   9069:        if(j==i) continue;
                   9070:        for(k=1; k<=ncovmodel;k++){
                   9071:          jj++;
                   9072:          ca[0]= k+'a'-1;ca[1]='\0';
                   9073:          if(itimes==1){
                   9074:            printf("#%1d%1d%d",i,j,k);
                   9075:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   9076:          }else{
                   9077:            printf("%1d%1d%d",i,j,k);
                   9078:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   9079:            /*  printf(" %.5le",matcov[i][j]); */
                   9080:          }
                   9081:          ll=0;
                   9082:          for(li=1;li <=nlstate; li++){
                   9083:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   9084:              if(lj==li) continue;
                   9085:              for(lk=1;lk<=ncovmodel;lk++){
                   9086:                ll++;
                   9087:                if(ll<=jj){
                   9088:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   9089:                  if(ll<jj){
                   9090:                    if(itimes==1){
                   9091:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9092:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9093:                    }else{
                   9094:                      printf(" 0.");
                   9095:                      fprintf(ficparo," 0.");
                   9096:                    }
                   9097:                  }else{
                   9098:                    if(itimes==1){
                   9099:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   9100:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   9101:                    }else{
                   9102:                      printf(" 0.");
                   9103:                      fprintf(ficparo," 0.");
                   9104:                    }
                   9105:                  }
                   9106:                }
                   9107:              } /* end lk */
                   9108:            } /* end lj */
                   9109:          } /* end li */
                   9110:          printf("\n");
                   9111:          fprintf(ficparo,"\n");
                   9112:          numlinepar++;
                   9113:        } /* end k*/
                   9114:       } /*end j */
                   9115:     } /* end i */
                   9116:   } /* end itimes */
                   9117: 
                   9118: } /* end of prwizard */
                   9119: /******************* Gompertz Likelihood ******************************/
                   9120: double gompertz(double x[])
                   9121: { 
1.302     brouard  9122:   double A=0.0,B=0.,L=0.0,sump=0.,num=0.;
1.126     brouard  9123:   int i,n=0; /* n is the size of the sample */
                   9124: 
1.220     brouard  9125:   for (i=1;i<=imx ; i++) {
1.126     brouard  9126:     sump=sump+weight[i];
                   9127:     /*    sump=sump+1;*/
                   9128:     num=num+1;
                   9129:   }
1.302     brouard  9130:   L=0.0;
                   9131:   /* agegomp=AGEGOMP; */
1.126     brouard  9132:   /* for (i=0; i<=imx; i++) 
                   9133:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9134: 
1.302     brouard  9135:   for (i=1;i<=imx ; i++) {
                   9136:     /* mu(a)=mu(agecomp)*exp(teta*(age-agegomp))
                   9137:        mu(a)=x[1]*exp(x[2]*(age-agegomp)); x[1] and x[2] are per year.
                   9138:      * L= Product mu(agedeces)exp(-\int_ageexam^agedc mu(u) du ) for a death between agedc (in month) 
                   9139:      *   and agedc +1 month, cens[i]=0: log(x[1]/YEARM)
                   9140:      * +
                   9141:      * exp(-\int_ageexam^agecens mu(u) du ) when censored, cens[i]=1
                   9142:      */
                   9143:      if (wav[i] > 1 || agedc[i] < AGESUP) {
                   9144:        if (cens[i] == 1){
                   9145:         A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9146:        } else if (cens[i] == 0){
1.126     brouard  9147:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
1.302     brouard  9148:          +log(x[1]/YEARM) +x[2]*(agedc[i]-agegomp)+log(YEARM);
                   9149:       } else
                   9150:         printf("Gompertz cens[%d] neither 1 nor 0\n",i);
1.126     brouard  9151:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
1.302     brouard  9152:        L=L+A*weight[i];
1.126     brouard  9153:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
1.302     brouard  9154:      }
                   9155:   }
1.126     brouard  9156: 
1.302     brouard  9157:   /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
1.126     brouard  9158:  
                   9159:   return -2*L*num/sump;
                   9160: }
                   9161: 
1.136     brouard  9162: #ifdef GSL
                   9163: /******************* Gompertz_f Likelihood ******************************/
                   9164: double gompertz_f(const gsl_vector *v, void *params)
                   9165: { 
1.302     brouard  9166:   double A=0.,B=0.,LL=0.0,sump=0.,num=0.;
1.136     brouard  9167:   double *x= (double *) v->data;
                   9168:   int i,n=0; /* n is the size of the sample */
                   9169: 
                   9170:   for (i=0;i<=imx-1 ; i++) {
                   9171:     sump=sump+weight[i];
                   9172:     /*    sump=sump+1;*/
                   9173:     num=num+1;
                   9174:   }
                   9175:  
                   9176:  
                   9177:   /* for (i=0; i<=imx; i++) 
                   9178:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9179:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9180:   for (i=1;i<=imx ; i++)
                   9181:     {
                   9182:       if (cens[i] == 1 && wav[i]>1)
                   9183:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9184:       
                   9185:       if (cens[i] == 0 && wav[i]>1)
                   9186:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9187:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9188:       
                   9189:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9190:       if (wav[i] > 1 ) { /* ??? */
                   9191:        LL=LL+A*weight[i];
                   9192:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9193:       }
                   9194:     }
                   9195: 
                   9196:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9197:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9198:  
                   9199:   return -2*LL*num/sump;
                   9200: }
                   9201: #endif
                   9202: 
1.126     brouard  9203: /******************* Printing html file ***********/
1.201     brouard  9204: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9205:                  int lastpass, int stepm, int weightopt, char model[],\
                   9206:                  int imx,  double p[],double **matcov,double agemortsup){
                   9207:   int i,k;
                   9208: 
                   9209:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9210:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9211:   for (i=1;i<=2;i++) 
                   9212:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9213:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9214:   fprintf(fichtm,"</ul>");
                   9215: 
                   9216: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9217: 
                   9218:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9219: 
                   9220:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9221:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9222: 
                   9223:  
                   9224:   fflush(fichtm);
                   9225: }
                   9226: 
                   9227: /******************* Gnuplot file **************/
1.201     brouard  9228: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9229: 
                   9230:   char dirfileres[132],optfileres[132];
1.164     brouard  9231: 
1.126     brouard  9232:   int ng;
                   9233: 
                   9234: 
                   9235:   /*#ifdef windows */
                   9236:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9237:     /*#endif */
                   9238: 
                   9239: 
                   9240:   strcpy(dirfileres,optionfilefiname);
                   9241:   strcpy(optfileres,"vpl");
1.199     brouard  9242:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9243:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9244:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9245:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9246:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9247: 
                   9248: } 
                   9249: 
1.136     brouard  9250: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9251: {
1.126     brouard  9252: 
1.136     brouard  9253:   /*-------- data file ----------*/
                   9254:   FILE *fic;
                   9255:   char dummy[]="                         ";
1.240     brouard  9256:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9257:   int lstra;
1.136     brouard  9258:   int linei, month, year,iout;
1.302     brouard  9259:   int noffset=0; /* This is the offset if BOM data file */
1.136     brouard  9260:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9261:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9262:   char *stratrunc;
1.223     brouard  9263: 
1.240     brouard  9264:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9265:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9266: 
1.240     brouard  9267:   for(v=1; v <=ncovcol;v++){
                   9268:     DummyV[v]=0;
                   9269:     FixedV[v]=0;
                   9270:   }
                   9271:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9272:     DummyV[v]=1;
                   9273:     FixedV[v]=0;
                   9274:   }
                   9275:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9276:     DummyV[v]=0;
                   9277:     FixedV[v]=1;
                   9278:   }
                   9279:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9280:     DummyV[v]=1;
                   9281:     FixedV[v]=1;
                   9282:   }
                   9283:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9284:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9285:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9286:   }
1.126     brouard  9287: 
1.136     brouard  9288:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9289:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9290:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9291:   }
1.126     brouard  9292: 
1.302     brouard  9293:     /* Is it a BOM UTF-8 Windows file? */
                   9294:   /* First data line */
                   9295:   linei=0;
                   9296:   while(fgets(line, MAXLINE, fic)) {
                   9297:     noffset=0;
                   9298:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   9299:     {
                   9300:       noffset=noffset+3;
                   9301:       printf("# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);fflush(stdout);
                   9302:       fprintf(ficlog,"# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);
                   9303:       fflush(ficlog); return 1;
                   9304:     }
                   9305:     /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   9306:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
                   9307:     {
                   9308:       noffset=noffset+2;
1.304     brouard  9309:       printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9310:       fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9311:       fflush(ficlog); return 1;
                   9312:     }
                   9313:     else if( line[0] == 0 && line[1] == 0)
                   9314:     {
                   9315:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   9316:        noffset=noffset+4;
1.304     brouard  9317:        printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9318:        fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9319:        fflush(ficlog); return 1;
                   9320:       }
                   9321:     } else{
                   9322:       ;/*printf(" Not a BOM file\n");*/
                   9323:     }
                   9324:         /* If line starts with a # it is a comment */
                   9325:     if (line[noffset] == '#') {
                   9326:       linei=linei+1;
                   9327:       break;
                   9328:     }else{
                   9329:       break;
                   9330:     }
                   9331:   }
                   9332:   fclose(fic);
                   9333:   if((fic=fopen(datafile,"r"))==NULL)    {
                   9334:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9335:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
                   9336:   }
                   9337:   /* Not a Bom file */
                   9338:   
1.136     brouard  9339:   i=1;
                   9340:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9341:     linei=linei+1;
                   9342:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9343:       if(line[j] == '\t')
                   9344:        line[j] = ' ';
                   9345:     }
                   9346:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9347:       ;
                   9348:     };
                   9349:     line[j+1]=0;  /* Trims blanks at end of line */
                   9350:     if(line[0]=='#'){
                   9351:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9352:       printf("Comment line\n%s\n",line);
                   9353:       continue;
                   9354:     }
                   9355:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9356:     strcpy(line, linetmp);
1.223     brouard  9357:     
                   9358:     /* Loops on waves */
                   9359:     for (j=maxwav;j>=1;j--){
                   9360:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9361:        cutv(stra, strb, line, ' '); 
                   9362:        if(strb[0]=='.') { /* Missing value */
                   9363:          lval=-1;
                   9364:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9365:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9366:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9367:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9368:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9369:            return 1;
                   9370:          }
                   9371:        }else{
                   9372:          errno=0;
                   9373:          /* what_kind_of_number(strb); */
                   9374:          dval=strtod(strb,&endptr); 
                   9375:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9376:          /* if(strb != endptr && *endptr == '\0') */
                   9377:          /*    dval=dlval; */
                   9378:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9379:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9380:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9381:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9382:            return 1;
                   9383:          }
                   9384:          cotqvar[j][iv][i]=dval; 
                   9385:          cotvar[j][ntv+iv][i]=dval; 
                   9386:        }
                   9387:        strcpy(line,stra);
1.223     brouard  9388:       }/* end loop ntqv */
1.225     brouard  9389:       
1.223     brouard  9390:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9391:        cutv(stra, strb, line, ' '); 
                   9392:        if(strb[0]=='.') { /* Missing value */
                   9393:          lval=-1;
                   9394:        }else{
                   9395:          errno=0;
                   9396:          lval=strtol(strb,&endptr,10); 
                   9397:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9398:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9399:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9400:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9401:            return 1;
                   9402:          }
                   9403:        }
                   9404:        if(lval <-1 || lval >1){
                   9405:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9406:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9407:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9408:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9409:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9410:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9411:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9412:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9413:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9414:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9415:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9416:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9417:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9418:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9419:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9420:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9421:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9422:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9423:          return 1;
                   9424:        }
                   9425:        cotvar[j][iv][i]=(double)(lval);
                   9426:        strcpy(line,stra);
1.223     brouard  9427:       }/* end loop ntv */
1.225     brouard  9428:       
1.223     brouard  9429:       /* Statuses  at wave */
1.137     brouard  9430:       cutv(stra, strb, line, ' '); 
1.223     brouard  9431:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9432:        lval=-1;
1.136     brouard  9433:       }else{
1.238     brouard  9434:        errno=0;
                   9435:        lval=strtol(strb,&endptr,10); 
                   9436:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9437:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9438:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9439:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9440:          return 1;
                   9441:        }
1.136     brouard  9442:       }
1.225     brouard  9443:       
1.136     brouard  9444:       s[j][i]=lval;
1.225     brouard  9445:       
1.223     brouard  9446:       /* Date of Interview */
1.136     brouard  9447:       strcpy(line,stra);
                   9448:       cutv(stra, strb,line,' ');
1.169     brouard  9449:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9450:       }
1.169     brouard  9451:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9452:        month=99;
                   9453:        year=9999;
1.136     brouard  9454:       }else{
1.225     brouard  9455:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9456:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9457:        return 1;
1.136     brouard  9458:       }
                   9459:       anint[j][i]= (double) year; 
1.302     brouard  9460:       mint[j][i]= (double)month;
                   9461:       /* if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){ */
                   9462:       /*       printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9463:       /*       fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9464:       /* } */
1.136     brouard  9465:       strcpy(line,stra);
1.223     brouard  9466:     } /* End loop on waves */
1.225     brouard  9467:     
1.223     brouard  9468:     /* Date of death */
1.136     brouard  9469:     cutv(stra, strb,line,' '); 
1.169     brouard  9470:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9471:     }
1.169     brouard  9472:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9473:       month=99;
                   9474:       year=9999;
                   9475:     }else{
1.141     brouard  9476:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9477:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9478:       return 1;
1.136     brouard  9479:     }
                   9480:     andc[i]=(double) year; 
                   9481:     moisdc[i]=(double) month; 
                   9482:     strcpy(line,stra);
                   9483:     
1.223     brouard  9484:     /* Date of birth */
1.136     brouard  9485:     cutv(stra, strb,line,' '); 
1.169     brouard  9486:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9487:     }
1.169     brouard  9488:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9489:       month=99;
                   9490:       year=9999;
                   9491:     }else{
1.141     brouard  9492:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9493:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9494:       return 1;
1.136     brouard  9495:     }
                   9496:     if (year==9999) {
1.141     brouard  9497:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9498:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9499:       return 1;
                   9500:       
1.136     brouard  9501:     }
                   9502:     annais[i]=(double)(year);
1.302     brouard  9503:     moisnais[i]=(double)(month);
                   9504:     for (j=1;j<=maxwav;j++){
                   9505:       if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){
                   9506:        printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j,(int)moisnais[i],(int)annais[i]);
                   9507:        fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j, (int)moisnais[i],(int)annais[i]);
                   9508:       }
                   9509:     }
                   9510: 
1.136     brouard  9511:     strcpy(line,stra);
1.225     brouard  9512:     
1.223     brouard  9513:     /* Sample weight */
1.136     brouard  9514:     cutv(stra, strb,line,' '); 
                   9515:     errno=0;
                   9516:     dval=strtod(strb,&endptr); 
                   9517:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9518:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9519:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9520:       fflush(ficlog);
                   9521:       return 1;
                   9522:     }
                   9523:     weight[i]=dval; 
                   9524:     strcpy(line,stra);
1.225     brouard  9525:     
1.223     brouard  9526:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9527:       cutv(stra, strb, line, ' '); 
                   9528:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9529:        lval=-1;
1.311   ! brouard  9530:        coqvar[iv][i]=NAN; 
        !          9531:        covar[ncovcol+iv][i]=NAN; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9532:       }else{
1.225     brouard  9533:        errno=0;
                   9534:        /* what_kind_of_number(strb); */
                   9535:        dval=strtod(strb,&endptr);
                   9536:        /* if(strb != endptr && *endptr == '\0') */
                   9537:        /*   dval=dlval; */
                   9538:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9539:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9540:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9541:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9542:          return 1;
                   9543:        }
                   9544:        coqvar[iv][i]=dval; 
1.226     brouard  9545:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9546:       }
                   9547:       strcpy(line,stra);
                   9548:     }/* end loop nqv */
1.136     brouard  9549:     
1.223     brouard  9550:     /* Covariate values */
1.136     brouard  9551:     for (j=ncovcol;j>=1;j--){
                   9552:       cutv(stra, strb,line,' '); 
1.223     brouard  9553:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9554:        lval=-1;
1.136     brouard  9555:       }else{
1.225     brouard  9556:        errno=0;
                   9557:        lval=strtol(strb,&endptr,10); 
                   9558:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9559:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9560:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9561:          return 1;
                   9562:        }
1.136     brouard  9563:       }
                   9564:       if(lval <-1 || lval >1){
1.225     brouard  9565:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9566:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9567:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9568:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9569:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9570:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9571:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9572:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9573:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9574:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9575:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9576:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9577:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9578:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9579:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9580:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9581:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9582:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9583:        return 1;
1.136     brouard  9584:       }
                   9585:       covar[j][i]=(double)(lval);
                   9586:       strcpy(line,stra);
                   9587:     }  
                   9588:     lstra=strlen(stra);
1.225     brouard  9589:     
1.136     brouard  9590:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9591:       stratrunc = &(stra[lstra-9]);
                   9592:       num[i]=atol(stratrunc);
                   9593:     }
                   9594:     else
                   9595:       num[i]=atol(stra);
                   9596:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9597:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9598:     
                   9599:     i=i+1;
                   9600:   } /* End loop reading  data */
1.225     brouard  9601:   
1.136     brouard  9602:   *imax=i-1; /* Number of individuals */
                   9603:   fclose(fic);
1.225     brouard  9604:   
1.136     brouard  9605:   return (0);
1.164     brouard  9606:   /* endread: */
1.225     brouard  9607:   printf("Exiting readdata: ");
                   9608:   fclose(fic);
                   9609:   return (1);
1.223     brouard  9610: }
1.126     brouard  9611: 
1.234     brouard  9612: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9613:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9614:   while (*p2 == ' ')
1.234     brouard  9615:     p2++; 
                   9616:   /* while ((*p1++ = *p2++) !=0) */
                   9617:   /*   ; */
                   9618:   /* do */
                   9619:   /*   while (*p2 == ' ') */
                   9620:   /*     p2++; */
                   9621:   /* while (*p1++ == *p2++); */
                   9622:   *stri=p2; 
1.145     brouard  9623: }
                   9624: 
1.235     brouard  9625: int decoderesult ( char resultline[], int nres)
1.230     brouard  9626: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9627: {
1.235     brouard  9628:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9629:   char resultsav[MAXLINE];
1.234     brouard  9630:   int resultmodel[MAXLINE];
                   9631:   int modelresult[MAXLINE];
1.230     brouard  9632:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9633: 
1.234     brouard  9634:   removefirstspace(&resultline);
1.230     brouard  9635: 
                   9636:   if (strstr(resultline,"v") !=0){
                   9637:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9638:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9639:     return 1;
                   9640:   }
                   9641:   trimbb(resultsav, resultline);
                   9642:   if (strlen(resultsav) >1){
                   9643:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9644:   }
1.253     brouard  9645:   if(j == 0){ /* Resultline but no = */
                   9646:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9647:     return (0);
                   9648:   }
1.234     brouard  9649:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
1.310     brouard  9650:     printf("ERROR: the number of variables in the resultline, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
                   9651:     fprintf(ficlog,"ERROR: the number of variables in the resultline, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
1.234     brouard  9652:   }
                   9653:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9654:     if(nbocc(resultsav,'=') >1){
                   9655:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
1.310     brouard  9656:                                      resultsav= V4=1 V5=25.1 V3=0 stra= V5=25.1 V3=0 strb= V4=1 */
1.234     brouard  9657:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9658:     }else
                   9659:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9660:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9661:     
1.230     brouard  9662:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9663:     Tvarsel[k]=atoi(strc);
                   9664:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9665:     /* cptcovsel++;     */
                   9666:     if (nbocc(stra,'=') >0)
                   9667:       strcpy(resultsav,stra); /* and analyzes it */
                   9668:   }
1.235     brouard  9669:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9670:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9671:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9672:       match=0;
1.236     brouard  9673:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9674:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9675:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9676:          match=1;
                   9677:          break;
                   9678:        }
                   9679:       }
                   9680:       if(match == 0){
1.310     brouard  9681:        printf("Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9682:        fprintf(ficlog,"Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9683:        return 1;
1.234     brouard  9684:       }
                   9685:     }
                   9686:   }
1.235     brouard  9687:   /* Checking for missing or useless values in comparison of current model needs */
                   9688:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9689:     match=0;
1.235     brouard  9690:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9691:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9692:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9693:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9694:          ++match;
                   9695:        }
                   9696:       }
                   9697:     }
                   9698:     if(match == 0){
                   9699:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
1.310     brouard  9700:       fprintf(ficlog,"Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9701:       return 1;
1.234     brouard  9702:     }else if(match > 1){
                   9703:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
1.310     brouard  9704:       fprintf(ficlog,"Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9705:       return 1;
1.234     brouard  9706:     }
                   9707:   }
1.235     brouard  9708:       
1.234     brouard  9709:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9710:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9711:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9712:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9713:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9714:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9715:   /*    1 0 0 0 */
                   9716:   /*    2 1 0 0 */
                   9717:   /*    3 0 1 0 */ 
                   9718:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9719:   /*    5 0 0 1 */
                   9720:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9721:   /*    7 0 1 1 */
                   9722:   /*    8 1 1 1 */
1.237     brouard  9723:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9724:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9725:   /* V5*age V5 known which value for nres?  */
                   9726:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9727:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9728:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9729:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9730:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9731:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9732:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9733:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9734:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9735:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9736:       k4++;;
                   9737:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9738:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9739:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9740:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9741:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9742:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9743:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9744:       k4q++;;
                   9745:     }
                   9746:   }
1.234     brouard  9747:   
1.235     brouard  9748:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9749:   return (0);
                   9750: }
1.235     brouard  9751: 
1.230     brouard  9752: int decodemodel( char model[], int lastobs)
                   9753:  /**< This routine decodes the model and returns:
1.224     brouard  9754:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9755:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9756:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9757:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9758:        * - cptcovage number of covariates with age*products =2
                   9759:        * - cptcovs number of simple covariates
                   9760:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9761:        *     which is a new column after the 9 (ncovcol) variables. 
                   9762:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9763:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9764:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9765:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9766:        */
1.136     brouard  9767: {
1.238     brouard  9768:   int i, j, k, ks, v;
1.227     brouard  9769:   int  j1, k1, k2, k3, k4;
1.136     brouard  9770:   char modelsav[80];
1.145     brouard  9771:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9772:   char *strpt;
1.136     brouard  9773: 
1.145     brouard  9774:   /*removespace(model);*/
1.136     brouard  9775:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9776:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9777:     if (strstr(model,"AGE") !=0){
1.192     brouard  9778:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9779:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9780:       return 1;
                   9781:     }
1.141     brouard  9782:     if (strstr(model,"v") !=0){
                   9783:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9784:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9785:       return 1;
                   9786:     }
1.187     brouard  9787:     strcpy(modelsav,model); 
                   9788:     if ((strpt=strstr(model,"age*age")) !=0){
                   9789:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9790:       if(strpt != model){
1.234     brouard  9791:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9792:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9793:  corresponding column of parameters.\n",model);
1.234     brouard  9794:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9795:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9796:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9797:        return 1;
1.225     brouard  9798:       }
1.187     brouard  9799:       nagesqr=1;
                   9800:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9801:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9802:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9803:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9804:       else 
1.234     brouard  9805:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9806:     }else
                   9807:       nagesqr=0;
                   9808:     if (strlen(modelsav) >1){
                   9809:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9810:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9811:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9812:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9813:                     * cst, age and age*age 
                   9814:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9815:       /* including age products which are counted in cptcovage.
                   9816:        * but the covariates which are products must be treated 
                   9817:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9818:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9819:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9820:       
                   9821:       
1.187     brouard  9822:       /*   Design
                   9823:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9824:        *  <          ncovcol=8                >
                   9825:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9826:        *   k=  1    2      3       4     5       6      7        8
                   9827:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9828:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9829:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9830:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9831:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9832:        *  Tage[++cptcovage]=k
                   9833:        *       if products, new covar are created after ncovcol with k1
                   9834:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9835:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9836:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9837:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9838:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9839:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9840:        *  <          ncovcol=8                >
                   9841:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9842:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9843:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9844:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9845:        * p Tprod[1]@2={                         6, 5}
                   9846:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9847:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9848:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9849:        *How to reorganize?
                   9850:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9851:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9852:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9853:        * Struct []
                   9854:        */
1.225     brouard  9855:       
1.187     brouard  9856:       /* This loop fills the array Tvar from the string 'model'.*/
                   9857:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9858:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9859:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9860:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9861:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9862:       /*       k=1 Tvar[1]=2 (from V2) */
                   9863:       /*       k=5 Tvar[5] */
                   9864:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9865:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9866:       /*       } */
1.198     brouard  9867:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9868:       /*
                   9869:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9870:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9871:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9872:       }
1.187     brouard  9873:       cptcovage=0;
                   9874:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9875:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9876:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9877:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9878:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9879:        /*scanf("%d",i);*/
                   9880:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9881:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9882:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9883:            /* covar is not filled and then is empty */
                   9884:            cptcovprod--;
                   9885:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9886:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9887:            Typevar[k]=1;  /* 1 for age product */
                   9888:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9889:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9890:            /*printf("stre=%s ", stre);*/
                   9891:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9892:            cptcovprod--;
                   9893:            cutl(stre,strb,strc,'V');
                   9894:            Tvar[k]=atoi(stre);
                   9895:            Typevar[k]=1;  /* 1 for age product */
                   9896:            cptcovage++;
                   9897:            Tage[cptcovage]=k;
                   9898:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9899:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9900:            cptcovn++;
                   9901:            cptcovprodnoage++;k1++;
                   9902:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9903:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9904:                                                because this model-covariate is a construction we invent a new column
                   9905:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9906:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9907:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9908:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9909:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9910:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9911:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9912:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9913:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9914:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9915:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9916:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9917:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9918:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9919:            for (i=1; i<=lastobs;i++){
                   9920:              /* Computes the new covariate which is a product of
                   9921:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9922:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9923:            }
                   9924:          } /* End age is not in the model */
                   9925:        } /* End if model includes a product */
                   9926:        else { /* no more sum */
                   9927:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9928:          /*  scanf("%d",i);*/
                   9929:          cutl(strd,strc,strb,'V');
                   9930:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9931:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9932:          Tvar[k]=atoi(strd);
                   9933:          Typevar[k]=0;  /* 0 for simple covariates */
                   9934:        }
                   9935:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9936:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9937:                                  scanf("%d",i);*/
1.187     brouard  9938:       } /* end of loop + on total covariates */
                   9939:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9940:   } /* end if strlen(model == 0) */
1.136     brouard  9941:   
                   9942:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9943:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9944:   
1.136     brouard  9945:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9946:      printf("cptcovprod=%d ", cptcovprod);
                   9947:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9948:      scanf("%d ",i);*/
                   9949: 
                   9950: 
1.230     brouard  9951: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9952:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9953: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9954:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9955:    k =           1    2   3     4       5       6      7      8        9
                   9956:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9957:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9958:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9959:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9960:          Tmodelind[combination of covar]=k;
1.225     brouard  9961: */  
                   9962: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9963:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9964:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9965:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9966:   printf("Model=%s\n\
                   9967: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9968: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9969: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9970:   fprintf(ficlog,"Model=%s\n\
                   9971: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9972: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9973: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  9974:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  9975:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   9976:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  9977:       Fixed[k]= 0;
                   9978:       Dummy[k]= 0;
1.225     brouard  9979:       ncoveff++;
1.232     brouard  9980:       ncovf++;
1.234     brouard  9981:       nsd++;
                   9982:       modell[k].maintype= FTYPE;
                   9983:       TvarsD[nsd]=Tvar[k];
                   9984:       TvarsDind[nsd]=k;
                   9985:       TvarF[ncovf]=Tvar[k];
                   9986:       TvarFind[ncovf]=k;
                   9987:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9988:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9989:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   9990:       Fixed[k]= 0;
                   9991:       Dummy[k]= 0;
                   9992:       ncoveff++;
                   9993:       ncovf++;
                   9994:       modell[k].maintype= FTYPE;
                   9995:       TvarF[ncovf]=Tvar[k];
                   9996:       TvarFind[ncovf]=k;
1.230     brouard  9997:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  9998:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  9999:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  10000:       Fixed[k]= 0;
                   10001:       Dummy[k]= 1;
1.230     brouard  10002:       nqfveff++;
1.234     brouard  10003:       modell[k].maintype= FTYPE;
                   10004:       modell[k].subtype= FQ;
                   10005:       nsq++;
                   10006:       TvarsQ[nsq]=Tvar[k];
                   10007:       TvarsQind[nsq]=k;
1.232     brouard  10008:       ncovf++;
1.234     brouard  10009:       TvarF[ncovf]=Tvar[k];
                   10010:       TvarFind[ncovf]=k;
1.231     brouard  10011:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  10012:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  10013:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  10014:       Fixed[k]= 1;
                   10015:       Dummy[k]= 0;
1.225     brouard  10016:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  10017:       modell[k].maintype= VTYPE;
                   10018:       modell[k].subtype= VD;
                   10019:       nsd++;
                   10020:       TvarsD[nsd]=Tvar[k];
                   10021:       TvarsDind[nsd]=k;
                   10022:       ncovv++; /* Only simple time varying variables */
                   10023:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10024:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10025:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   10026:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  10027:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   10028:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  10029:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  10030:       Fixed[k]= 1;
                   10031:       Dummy[k]= 1;
                   10032:       nqtveff++;
                   10033:       modell[k].maintype= VTYPE;
                   10034:       modell[k].subtype= VQ;
                   10035:       ncovv++; /* Only simple time varying variables */
                   10036:       nsq++;
                   10037:       TvarsQ[nsq]=Tvar[k];
                   10038:       TvarsQind[nsq]=k;
                   10039:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10040:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10041:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   10042:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  10043:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   10044:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   10045:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  10046:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  10047:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  10048:       ncova++;
                   10049:       TvarA[ncova]=Tvar[k];
                   10050:       TvarAind[ncova]=k;
1.231     brouard  10051:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  10052:        Fixed[k]= 2;
                   10053:        Dummy[k]= 2;
                   10054:        modell[k].maintype= ATYPE;
                   10055:        modell[k].subtype= APFD;
                   10056:        /* ncoveff++; */
1.227     brouard  10057:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  10058:        Fixed[k]= 2;
                   10059:        Dummy[k]= 3;
                   10060:        modell[k].maintype= ATYPE;
                   10061:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   10062:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  10063:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  10064:        Fixed[k]= 3;
                   10065:        Dummy[k]= 2;
                   10066:        modell[k].maintype= ATYPE;
                   10067:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   10068:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  10069:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10070:        Fixed[k]= 3;
                   10071:        Dummy[k]= 3;
                   10072:        modell[k].maintype= ATYPE;
                   10073:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   10074:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  10075:       }
                   10076:     }else if (Typevar[k] == 2) {  /* product without age */
                   10077:       k1=Tposprod[k];
                   10078:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  10079:        if(Tvard[k1][2] <=ncovcol){
                   10080:          Fixed[k]= 1;
                   10081:          Dummy[k]= 0;
                   10082:          modell[k].maintype= FTYPE;
                   10083:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   10084:          ncovf++; /* Fixed variables without age */
                   10085:          TvarF[ncovf]=Tvar[k];
                   10086:          TvarFind[ncovf]=k;
                   10087:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10088:          Fixed[k]= 0;  /* or 2 ?*/
                   10089:          Dummy[k]= 1;
                   10090:          modell[k].maintype= FTYPE;
                   10091:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   10092:          ncovf++; /* Varying variables without age */
                   10093:          TvarF[ncovf]=Tvar[k];
                   10094:          TvarFind[ncovf]=k;
                   10095:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10096:          Fixed[k]= 1;
                   10097:          Dummy[k]= 0;
                   10098:          modell[k].maintype= VTYPE;
                   10099:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   10100:          ncovv++; /* Varying variables without age */
                   10101:          TvarV[ncovv]=Tvar[k];
                   10102:          TvarVind[ncovv]=k;
                   10103:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10104:          Fixed[k]= 1;
                   10105:          Dummy[k]= 1;
                   10106:          modell[k].maintype= VTYPE;
                   10107:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   10108:          ncovv++; /* Varying variables without age */
                   10109:          TvarV[ncovv]=Tvar[k];
                   10110:          TvarVind[ncovv]=k;
                   10111:        }
1.227     brouard  10112:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  10113:        if(Tvard[k1][2] <=ncovcol){
                   10114:          Fixed[k]= 0;  /* or 2 ?*/
                   10115:          Dummy[k]= 1;
                   10116:          modell[k].maintype= FTYPE;
                   10117:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   10118:          ncovf++; /* Fixed variables without age */
                   10119:          TvarF[ncovf]=Tvar[k];
                   10120:          TvarFind[ncovf]=k;
                   10121:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10122:          Fixed[k]= 1;
                   10123:          Dummy[k]= 1;
                   10124:          modell[k].maintype= VTYPE;
                   10125:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   10126:          ncovv++; /* Varying variables without age */
                   10127:          TvarV[ncovv]=Tvar[k];
                   10128:          TvarVind[ncovv]=k;
                   10129:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10130:          Fixed[k]= 1;
                   10131:          Dummy[k]= 1;
                   10132:          modell[k].maintype= VTYPE;
                   10133:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   10134:          ncovv++; /* Varying variables without age */
                   10135:          TvarV[ncovv]=Tvar[k];
                   10136:          TvarVind[ncovv]=k;
                   10137:          ncovv++; /* Varying variables without age */
                   10138:          TvarV[ncovv]=Tvar[k];
                   10139:          TvarVind[ncovv]=k;
                   10140:        }
1.227     brouard  10141:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  10142:        if(Tvard[k1][2] <=ncovcol){
                   10143:          Fixed[k]= 1;
                   10144:          Dummy[k]= 1;
                   10145:          modell[k].maintype= VTYPE;
                   10146:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   10147:          ncovv++; /* Varying variables without age */
                   10148:          TvarV[ncovv]=Tvar[k];
                   10149:          TvarVind[ncovv]=k;
                   10150:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10151:          Fixed[k]= 1;
                   10152:          Dummy[k]= 1;
                   10153:          modell[k].maintype= VTYPE;
                   10154:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   10155:          ncovv++; /* Varying variables without age */
                   10156:          TvarV[ncovv]=Tvar[k];
                   10157:          TvarVind[ncovv]=k;
                   10158:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10159:          Fixed[k]= 1;
                   10160:          Dummy[k]= 0;
                   10161:          modell[k].maintype= VTYPE;
                   10162:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   10163:          ncovv++; /* Varying variables without age */
                   10164:          TvarV[ncovv]=Tvar[k];
                   10165:          TvarVind[ncovv]=k;
                   10166:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10167:          Fixed[k]= 1;
                   10168:          Dummy[k]= 1;
                   10169:          modell[k].maintype= VTYPE;
                   10170:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   10171:          ncovv++; /* Varying variables without age */
                   10172:          TvarV[ncovv]=Tvar[k];
                   10173:          TvarVind[ncovv]=k;
                   10174:        }
1.227     brouard  10175:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10176:        if(Tvard[k1][2] <=ncovcol){
                   10177:          Fixed[k]= 1;
                   10178:          Dummy[k]= 1;
                   10179:          modell[k].maintype= VTYPE;
                   10180:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   10181:          ncovv++; /* Varying variables without age */
                   10182:          TvarV[ncovv]=Tvar[k];
                   10183:          TvarVind[ncovv]=k;
                   10184:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10185:          Fixed[k]= 1;
                   10186:          Dummy[k]= 1;
                   10187:          modell[k].maintype= VTYPE;
                   10188:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   10189:          ncovv++; /* Varying variables without age */
                   10190:          TvarV[ncovv]=Tvar[k];
                   10191:          TvarVind[ncovv]=k;
                   10192:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10193:          Fixed[k]= 1;
                   10194:          Dummy[k]= 1;
                   10195:          modell[k].maintype= VTYPE;
                   10196:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   10197:          ncovv++; /* Varying variables without age */
                   10198:          TvarV[ncovv]=Tvar[k];
                   10199:          TvarVind[ncovv]=k;
                   10200:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10201:          Fixed[k]= 1;
                   10202:          Dummy[k]= 1;
                   10203:          modell[k].maintype= VTYPE;
                   10204:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10205:          ncovv++; /* Varying variables without age */
                   10206:          TvarV[ncovv]=Tvar[k];
                   10207:          TvarVind[ncovv]=k;
                   10208:        }
1.227     brouard  10209:       }else{
1.240     brouard  10210:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10211:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10212:       } /*end k1*/
1.225     brouard  10213:     }else{
1.226     brouard  10214:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10215:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10216:     }
1.227     brouard  10217:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10218:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10219:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10220:   }
                   10221:   /* Searching for doublons in the model */
                   10222:   for(k1=1; k1<= cptcovt;k1++){
                   10223:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10224:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10225:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10226:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10227:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10228:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10229:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10230:            return(1);
                   10231:          }
                   10232:        }else if (Typevar[k1] ==2){
                   10233:          k3=Tposprod[k1];
                   10234:          k4=Tposprod[k2];
                   10235:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10236:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10237:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10238:            return(1);
                   10239:          }
                   10240:        }
1.227     brouard  10241:       }
                   10242:     }
1.225     brouard  10243:   }
                   10244:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10245:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10246:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10247:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10248:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10249:   /*endread:*/
1.225     brouard  10250:   printf("Exiting decodemodel: ");
                   10251:   return (1);
1.136     brouard  10252: }
                   10253: 
1.169     brouard  10254: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10255: {/* Check ages at death */
1.136     brouard  10256:   int i, m;
1.218     brouard  10257:   int firstone=0;
                   10258:   
1.136     brouard  10259:   for (i=1; i<=imx; i++) {
                   10260:     for(m=2; (m<= maxwav); m++) {
                   10261:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10262:        anint[m][i]=9999;
1.216     brouard  10263:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10264:          s[m][i]=-1;
1.136     brouard  10265:       }
                   10266:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10267:        *nberr = *nberr + 1;
1.218     brouard  10268:        if(firstone == 0){
                   10269:          firstone=1;
1.260     brouard  10270:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10271:        }
1.262     brouard  10272:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10273:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10274:       }
                   10275:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10276:        (*nberr)++;
1.259     brouard  10277:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10278:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10279:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10280:       }
                   10281:     }
                   10282:   }
                   10283: 
                   10284:   for (i=1; i<=imx; i++)  {
                   10285:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10286:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10287:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10288:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10289:          if(agedc[i]>0){
                   10290:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10291:              agev[m][i]=agedc[i];
1.214     brouard  10292:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10293:            }else {
1.136     brouard  10294:              if ((int)andc[i]!=9999){
                   10295:                nbwarn++;
                   10296:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10297:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10298:                agev[m][i]=-1;
                   10299:              }
                   10300:            }
1.169     brouard  10301:          } /* agedc > 0 */
1.214     brouard  10302:        } /* end if */
1.136     brouard  10303:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10304:                                 years but with the precision of a month */
                   10305:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10306:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10307:            agev[m][i]=1;
                   10308:          else if(agev[m][i] < *agemin){ 
                   10309:            *agemin=agev[m][i];
                   10310:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10311:          }
                   10312:          else if(agev[m][i] >*agemax){
                   10313:            *agemax=agev[m][i];
1.156     brouard  10314:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10315:          }
                   10316:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10317:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10318:        } /* en if 9*/
1.136     brouard  10319:        else { /* =9 */
1.214     brouard  10320:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10321:          agev[m][i]=1;
                   10322:          s[m][i]=-1;
                   10323:        }
                   10324:       }
1.214     brouard  10325:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10326:        agev[m][i]=1;
1.214     brouard  10327:       else{
                   10328:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10329:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10330:        agev[m][i]=0;
                   10331:       }
                   10332:     } /* End for lastpass */
                   10333:   }
1.136     brouard  10334:     
                   10335:   for (i=1; i<=imx; i++)  {
                   10336:     for(m=firstpass; (m<=lastpass); m++){
                   10337:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10338:        (*nberr)++;
1.136     brouard  10339:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10340:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10341:        return 1;
                   10342:       }
                   10343:     }
                   10344:   }
                   10345: 
                   10346:   /*for (i=1; i<=imx; i++){
                   10347:   for (m=firstpass; (m<lastpass); m++){
                   10348:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10349: }
                   10350: 
                   10351: }*/
                   10352: 
                   10353: 
1.139     brouard  10354:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10355:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10356: 
                   10357:   return (0);
1.164     brouard  10358:  /* endread:*/
1.136     brouard  10359:     printf("Exiting calandcheckages: ");
                   10360:     return (1);
                   10361: }
                   10362: 
1.172     brouard  10363: #if defined(_MSC_VER)
                   10364: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10365: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10366: //#include "stdafx.h"
                   10367: //#include <stdio.h>
                   10368: //#include <tchar.h>
                   10369: //#include <windows.h>
                   10370: //#include <iostream>
                   10371: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10372: 
                   10373: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10374: 
                   10375: BOOL IsWow64()
                   10376: {
                   10377:        BOOL bIsWow64 = FALSE;
                   10378: 
                   10379:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10380:        //  (HANDLE, PBOOL);
                   10381: 
                   10382:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10383: 
                   10384:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10385:        const char funcName[] = "IsWow64Process";
                   10386:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10387:                GetProcAddress(module, funcName);
                   10388: 
                   10389:        if (NULL != fnIsWow64Process)
                   10390:        {
                   10391:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10392:                        &bIsWow64))
                   10393:                        //throw std::exception("Unknown error");
                   10394:                        printf("Unknown error\n");
                   10395:        }
                   10396:        return bIsWow64 != FALSE;
                   10397: }
                   10398: #endif
1.177     brouard  10399: 
1.191     brouard  10400: void syscompilerinfo(int logged)
1.292     brouard  10401: {
                   10402: #include <stdint.h>
                   10403: 
                   10404:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10405:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10406:    /* /GS /W3 /Gy
                   10407:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10408:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10409:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10410:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10411:    */ 
                   10412:    /* 64 bits */
1.185     brouard  10413:    /*
                   10414:      /GS /W3 /Gy
                   10415:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10416:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10417:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10418:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10419:    /* Optimization are useless and O3 is slower than O2 */
                   10420:    /*
                   10421:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10422:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10423:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10424:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10425:    */
1.186     brouard  10426:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10427:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10428:       /PDB:"visual studio
                   10429:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10430:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10431:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10432:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10433:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10434:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10435:       uiAccess='false'"
                   10436:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10437:       /NOLOGO /TLBID:1
                   10438:    */
1.292     brouard  10439: 
                   10440: 
1.177     brouard  10441: #if defined __INTEL_COMPILER
1.178     brouard  10442: #if defined(__GNUC__)
                   10443:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10444: #endif
1.177     brouard  10445: #elif defined(__GNUC__) 
1.179     brouard  10446: #ifndef  __APPLE__
1.174     brouard  10447: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10448: #endif
1.177     brouard  10449:    struct utsname sysInfo;
1.178     brouard  10450:    int cross = CROSS;
                   10451:    if (cross){
                   10452:           printf("Cross-");
1.191     brouard  10453:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10454:    }
1.174     brouard  10455: #endif
                   10456: 
1.191     brouard  10457:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10458: #if defined(__clang__)
1.191     brouard  10459:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10460: #endif
                   10461: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10462:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10463: #endif
                   10464: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10465:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10466: #endif
                   10467: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10468:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10469: #endif
                   10470: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10471:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10472: #endif
                   10473: #if defined(_MSC_VER)
1.191     brouard  10474:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10475: #endif
                   10476: #if defined(__PGI)
1.191     brouard  10477:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10478: #endif
                   10479: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10480:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10481: #endif
1.191     brouard  10482:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10483:    
1.167     brouard  10484: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10485: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10486:     // Windows (x64 and x86)
1.191     brouard  10487:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10488: #elif __unix__ // all unices, not all compilers
                   10489:     // Unix
1.191     brouard  10490:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10491: #elif __linux__
                   10492:     // linux
1.191     brouard  10493:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10494: #elif __APPLE__
1.174     brouard  10495:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10496:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10497: #endif
                   10498: 
                   10499: /*  __MINGW32__          */
                   10500: /*  __CYGWIN__  */
                   10501: /* __MINGW64__  */
                   10502: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10503: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10504: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10505: /* _WIN64  // Defined for applications for Win64. */
                   10506: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10507: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10508: 
1.167     brouard  10509: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10510:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10511: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10512:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10513: #else
1.191     brouard  10514:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10515: #endif
                   10516: 
1.169     brouard  10517: #if defined(__GNUC__)
                   10518: # if defined(__GNUC_PATCHLEVEL__)
                   10519: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10520:                             + __GNUC_MINOR__ * 100 \
                   10521:                             + __GNUC_PATCHLEVEL__)
                   10522: # else
                   10523: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10524:                             + __GNUC_MINOR__ * 100)
                   10525: # endif
1.174     brouard  10526:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10527:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10528: 
                   10529:    if (uname(&sysInfo) != -1) {
                   10530:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10531:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10532:    }
                   10533:    else
                   10534:       perror("uname() error");
1.179     brouard  10535:    //#ifndef __INTEL_COMPILER 
                   10536: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10537:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10538:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10539: #endif
1.169     brouard  10540: #endif
1.172     brouard  10541: 
1.286     brouard  10542:    //   void main ()
1.172     brouard  10543:    //   {
1.169     brouard  10544: #if defined(_MSC_VER)
1.174     brouard  10545:    if (IsWow64()){
1.191     brouard  10546:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10547:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10548:    }
                   10549:    else{
1.191     brouard  10550:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10551:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10552:    }
1.172     brouard  10553:    //     printf("\nPress Enter to continue...");
                   10554:    //     getchar();
                   10555:    //   }
                   10556: 
1.169     brouard  10557: #endif
                   10558:    
1.167     brouard  10559: 
1.219     brouard  10560: }
1.136     brouard  10561: 
1.219     brouard  10562: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10563:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10564:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10565:   /* double ftolpl = 1.e-10; */
1.180     brouard  10566:   double age, agebase, agelim;
1.203     brouard  10567:   double tot;
1.180     brouard  10568: 
1.202     brouard  10569:   strcpy(filerespl,"PL_");
                   10570:   strcat(filerespl,fileresu);
                   10571:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10572:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10573:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10574:   }
1.288     brouard  10575:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10576:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10577:   pstamp(ficrespl);
1.288     brouard  10578:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10579:   fprintf(ficrespl,"#Age ");
                   10580:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10581:   fprintf(ficrespl,"\n");
1.180     brouard  10582:   
1.219     brouard  10583:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10584: 
1.219     brouard  10585:   agebase=ageminpar;
                   10586:   agelim=agemaxpar;
1.180     brouard  10587: 
1.227     brouard  10588:   /* i1=pow(2,ncoveff); */
1.234     brouard  10589:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10590:   if (cptcovn < 1){i1=1;}
1.180     brouard  10591: 
1.238     brouard  10592:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10593:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10594:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10595:        continue;
1.235     brouard  10596: 
1.238     brouard  10597:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10598:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10599:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10600:       /* k=k+1; */
                   10601:       /* to clean */
                   10602:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10603:       fprintf(ficrespl,"#******");
                   10604:       printf("#******");
                   10605:       fprintf(ficlog,"#******");
                   10606:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10607:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10608:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10609:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10610:       }
                   10611:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10612:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10613:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10614:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10615:       }
                   10616:       fprintf(ficrespl,"******\n");
                   10617:       printf("******\n");
                   10618:       fprintf(ficlog,"******\n");
                   10619:       if(invalidvarcomb[k]){
                   10620:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10621:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10622:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10623:        continue;
                   10624:       }
1.219     brouard  10625: 
1.238     brouard  10626:       fprintf(ficrespl,"#Age ");
                   10627:       for(j=1;j<=cptcoveff;j++) {
                   10628:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10629:       }
                   10630:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10631:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10632:     
1.238     brouard  10633:       for (age=agebase; age<=agelim; age++){
                   10634:        /* for (age=agebase; age<=agebase; age++){ */
                   10635:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10636:        fprintf(ficrespl,"%.0f ",age );
                   10637:        for(j=1;j<=cptcoveff;j++)
                   10638:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10639:        tot=0.;
                   10640:        for(i=1; i<=nlstate;i++){
                   10641:          tot +=  prlim[i][i];
                   10642:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10643:        }
                   10644:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10645:       } /* Age */
                   10646:       /* was end of cptcod */
                   10647:     } /* cptcov */
                   10648:   } /* nres */
1.219     brouard  10649:   return 0;
1.180     brouard  10650: }
                   10651: 
1.218     brouard  10652: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10653:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10654:        
                   10655:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10656:    * at any age between ageminpar and agemaxpar
                   10657:         */
1.235     brouard  10658:   int i, j, k, i1, nres=0 ;
1.217     brouard  10659:   /* double ftolpl = 1.e-10; */
                   10660:   double age, agebase, agelim;
                   10661:   double tot;
1.218     brouard  10662:   /* double ***mobaverage; */
                   10663:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10664: 
                   10665:   strcpy(fileresplb,"PLB_");
                   10666:   strcat(fileresplb,fileresu);
                   10667:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10668:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10669:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10670:   }
1.288     brouard  10671:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10672:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10673:   pstamp(ficresplb);
1.288     brouard  10674:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10675:   fprintf(ficresplb,"#Age ");
                   10676:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10677:   fprintf(ficresplb,"\n");
                   10678:   
1.218     brouard  10679:   
                   10680:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10681:   
                   10682:   agebase=ageminpar;
                   10683:   agelim=agemaxpar;
                   10684:   
                   10685:   
1.227     brouard  10686:   i1=pow(2,cptcoveff);
1.218     brouard  10687:   if (cptcovn < 1){i1=1;}
1.227     brouard  10688:   
1.238     brouard  10689:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10690:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10691:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10692:        continue;
                   10693:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10694:       fprintf(ficresplb,"#******");
                   10695:       printf("#******");
                   10696:       fprintf(ficlog,"#******");
                   10697:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10698:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10699:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10700:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10701:       }
                   10702:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10703:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10704:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10705:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10706:       }
                   10707:       fprintf(ficresplb,"******\n");
                   10708:       printf("******\n");
                   10709:       fprintf(ficlog,"******\n");
                   10710:       if(invalidvarcomb[k]){
                   10711:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10712:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10713:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10714:        continue;
                   10715:       }
1.218     brouard  10716:     
1.238     brouard  10717:       fprintf(ficresplb,"#Age ");
                   10718:       for(j=1;j<=cptcoveff;j++) {
                   10719:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10720:       }
                   10721:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10722:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10723:     
                   10724:     
1.238     brouard  10725:       for (age=agebase; age<=agelim; age++){
                   10726:        /* for (age=agebase; age<=agebase; age++){ */
                   10727:        if(mobilavproj > 0){
                   10728:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10729:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10730:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10731:        }else if (mobilavproj == 0){
                   10732:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10733:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10734:          exit(1);
                   10735:        }else{
                   10736:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10737:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10738:          /* printf("TOTOT\n"); */
                   10739:           /* exit(1); */
1.238     brouard  10740:        }
                   10741:        fprintf(ficresplb,"%.0f ",age );
                   10742:        for(j=1;j<=cptcoveff;j++)
                   10743:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10744:        tot=0.;
                   10745:        for(i=1; i<=nlstate;i++){
                   10746:          tot +=  bprlim[i][i];
                   10747:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10748:        }
                   10749:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10750:       } /* Age */
                   10751:       /* was end of cptcod */
1.255     brouard  10752:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10753:     } /* end of any combination */
                   10754:   } /* end of nres */  
1.218     brouard  10755:   /* hBijx(p, bage, fage); */
                   10756:   /* fclose(ficrespijb); */
                   10757:   
                   10758:   return 0;
1.217     brouard  10759: }
1.218     brouard  10760:  
1.180     brouard  10761: int hPijx(double *p, int bage, int fage){
                   10762:     /*------------- h Pij x at various ages ------------*/
                   10763: 
                   10764:   int stepsize;
                   10765:   int agelim;
                   10766:   int hstepm;
                   10767:   int nhstepm;
1.235     brouard  10768:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10769: 
                   10770:   double agedeb;
                   10771:   double ***p3mat;
                   10772: 
1.201     brouard  10773:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10774:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10775:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10776:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10777:     }
                   10778:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10779:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10780:   
                   10781:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10782:     /*if (stepm<=24) stepsize=2;*/
                   10783: 
                   10784:     agelim=AGESUP;
                   10785:     hstepm=stepsize*YEARM; /* Every year of age */
                   10786:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10787:                
1.180     brouard  10788:     /* hstepm=1;   aff par mois*/
                   10789:     pstamp(ficrespij);
                   10790:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10791:     i1= pow(2,cptcoveff);
1.218     brouard  10792:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10793:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10794:                /*      k=k+1;  */
1.235     brouard  10795:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10796:     for(k=1; k<=i1;k++){
1.253     brouard  10797:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10798:        continue;
1.183     brouard  10799:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10800:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10801:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10802:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10803:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10804:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10805:       }
1.183     brouard  10806:       fprintf(ficrespij,"******\n");
                   10807:       
                   10808:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10809:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10810:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10811:        
                   10812:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10813:        
1.183     brouard  10814:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10815:        oldm=oldms;savm=savms;
1.235     brouard  10816:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10817:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10818:        for(i=1; i<=nlstate;i++)
                   10819:          for(j=1; j<=nlstate+ndeath;j++)
                   10820:            fprintf(ficrespij," %1d-%1d",i,j);
                   10821:        fprintf(ficrespij,"\n");
                   10822:        for (h=0; h<=nhstepm; h++){
                   10823:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10824:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10825:          for(i=1; i<=nlstate;i++)
                   10826:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10827:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10828:          fprintf(ficrespij,"\n");
                   10829:        }
1.183     brouard  10830:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10831:        fprintf(ficrespij,"\n");
                   10832:       }
1.180     brouard  10833:       /*}*/
                   10834:     }
1.218     brouard  10835:     return 0;
1.180     brouard  10836: }
1.218     brouard  10837:  
                   10838:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10839:     /*------------- h Bij x at various ages ------------*/
                   10840: 
                   10841:   int stepsize;
1.218     brouard  10842:   /* int agelim; */
                   10843:        int ageminl;
1.217     brouard  10844:   int hstepm;
                   10845:   int nhstepm;
1.238     brouard  10846:   int h, i, i1, j, k, nres;
1.218     brouard  10847:        
1.217     brouard  10848:   double agedeb;
                   10849:   double ***p3mat;
1.218     brouard  10850:        
                   10851:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10852:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10853:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10854:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10855:   }
                   10856:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10857:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10858:   
                   10859:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10860:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10861:   
1.218     brouard  10862:   /* agelim=AGESUP; */
1.289     brouard  10863:   ageminl=AGEINF; /* was 30 */
1.218     brouard  10864:   hstepm=stepsize*YEARM; /* Every year of age */
                   10865:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10866:   
                   10867:   /* hstepm=1;   aff par mois*/
                   10868:   pstamp(ficrespijb);
1.255     brouard  10869:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10870:   i1= pow(2,cptcoveff);
1.218     brouard  10871:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10872:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10873:   /*   k=k+1;  */
1.238     brouard  10874:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10875:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10876:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10877:        continue;
                   10878:       fprintf(ficrespijb,"\n#****** ");
                   10879:       for(j=1;j<=cptcoveff;j++)
                   10880:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10881:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10882:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10883:       }
                   10884:       fprintf(ficrespijb,"******\n");
1.264     brouard  10885:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10886:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10887:        continue;
                   10888:       }
                   10889:       
                   10890:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10891:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10892:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
1.297     brouard  10893:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm+0.1)-1; /* Typically 20 years = 20*12/6=40 or 55*12/24=27.5-1.1=>27 */
                   10894:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 or 28*/
1.238     brouard  10895:        
                   10896:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10897:        
1.266     brouard  10898:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10899:        /* and memory limitations if stepm is small */
                   10900: 
1.238     brouard  10901:        /* oldm=oldms;savm=savms; */
                   10902:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10903:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10904:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10905:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10906:        for(i=1; i<=nlstate;i++)
                   10907:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10908:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10909:        fprintf(ficrespijb,"\n");
1.238     brouard  10910:        for (h=0; h<=nhstepm; h++){
                   10911:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10912:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10913:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10914:          for(i=1; i<=nlstate;i++)
                   10915:            for(j=1; j<=nlstate+ndeath;j++)
                   10916:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10917:          fprintf(ficrespijb,"\n");
                   10918:        }
                   10919:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10920:        fprintf(ficrespijb,"\n");
                   10921:       } /* end age deb */
                   10922:     } /* end combination */
                   10923:   } /* end nres */
1.218     brouard  10924:   return 0;
                   10925:  } /*  hBijx */
1.217     brouard  10926: 
1.180     brouard  10927: 
1.136     brouard  10928: /***********************************************/
                   10929: /**************** Main Program *****************/
                   10930: /***********************************************/
                   10931: 
                   10932: int main(int argc, char *argv[])
                   10933: {
                   10934: #ifdef GSL
                   10935:   const gsl_multimin_fminimizer_type *T;
                   10936:   size_t iteri = 0, it;
                   10937:   int rval = GSL_CONTINUE;
                   10938:   int status = GSL_SUCCESS;
                   10939:   double ssval;
                   10940: #endif
                   10941:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  10942:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   10943:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  10944:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10945:   int jj, ll, li, lj, lk;
1.136     brouard  10946:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10947:   int num_filled;
1.136     brouard  10948:   int itimes;
                   10949:   int NDIM=2;
                   10950:   int vpopbased=0;
1.235     brouard  10951:   int nres=0;
1.258     brouard  10952:   int endishere=0;
1.277     brouard  10953:   int noffset=0;
1.274     brouard  10954:   int ncurrv=0; /* Temporary variable */
                   10955:   
1.164     brouard  10956:   char ca[32], cb[32];
1.136     brouard  10957:   /*  FILE *fichtm; *//* Html File */
                   10958:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10959:   struct stat info;
1.191     brouard  10960:   double agedeb=0.;
1.194     brouard  10961: 
                   10962:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10963:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10964: 
1.165     brouard  10965:   double fret;
1.191     brouard  10966:   double dum=0.; /* Dummy variable */
1.136     brouard  10967:   double ***p3mat;
1.218     brouard  10968:   /* double ***mobaverage; */
1.164     brouard  10969: 
                   10970:   char line[MAXLINE];
1.197     brouard  10971:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10972: 
1.234     brouard  10973:   char  modeltemp[MAXLINE];
1.230     brouard  10974:   char resultline[MAXLINE];
                   10975:   
1.136     brouard  10976:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  10977:   char *tok, *val; /* pathtot */
1.290     brouard  10978:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  10979:   int c,  h , cpt, c2;
1.191     brouard  10980:   int jl=0;
                   10981:   int i1, j1, jk, stepsize=0;
1.194     brouard  10982:   int count=0;
                   10983: 
1.164     brouard  10984:   int *tab; 
1.136     brouard  10985:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.296     brouard  10986:   /* double anprojd, mprojd, jprojd; /\* For eventual projections *\/ */
                   10987:   /* double anprojf, mprojf, jprojf; */
                   10988:   /* double jintmean,mintmean,aintmean;   */
                   10989:   int prvforecast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   10990:   int prvbackcast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   10991:   double yrfproj= 10.0; /* Number of years of forward projections */
                   10992:   double yrbproj= 10.0; /* Number of years of backward projections */
                   10993:   int prevbcast=0; /* defined as global for mlikeli and mle, replacing backcast */
1.136     brouard  10994:   int mobilav=0,popforecast=0;
1.191     brouard  10995:   int hstepm=0, nhstepm=0;
1.136     brouard  10996:   int agemortsup;
                   10997:   float  sumlpop=0.;
                   10998:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   10999:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   11000: 
1.191     brouard  11001:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  11002:   double ftolpl=FTOL;
                   11003:   double **prlim;
1.217     brouard  11004:   double **bprlim;
1.136     brouard  11005:   double ***param; /* Matrix of parameters */
1.251     brouard  11006:   double ***paramstart; /* Matrix of starting parameter values */
                   11007:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  11008:   double **matcov; /* Matrix of covariance */
1.203     brouard  11009:   double **hess; /* Hessian matrix */
1.136     brouard  11010:   double ***delti3; /* Scale */
                   11011:   double *delti; /* Scale */
                   11012:   double ***eij, ***vareij;
                   11013:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  11014: 
1.136     brouard  11015:   double *epj, vepp;
1.164     brouard  11016: 
1.273     brouard  11017:   double dateprev1, dateprev2;
1.296     brouard  11018:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0, dateprojd=0, dateprojf=0;
                   11019:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0, datebackd=0, datebackf=0;
                   11020: 
1.217     brouard  11021: 
1.136     brouard  11022:   double **ximort;
1.145     brouard  11023:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  11024:   int *dcwave;
                   11025: 
1.164     brouard  11026:   char z[1]="c";
1.136     brouard  11027: 
                   11028:   /*char  *strt;*/
                   11029:   char strtend[80];
1.126     brouard  11030: 
1.164     brouard  11031: 
1.126     brouard  11032: /*   setlocale (LC_ALL, ""); */
                   11033: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   11034: /*   textdomain (PACKAGE); */
                   11035: /*   setlocale (LC_CTYPE, ""); */
                   11036: /*   setlocale (LC_MESSAGES, ""); */
                   11037: 
                   11038:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  11039:   rstart_time = time(NULL);  
                   11040:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   11041:   start_time = *localtime(&rstart_time);
1.126     brouard  11042:   curr_time=start_time;
1.157     brouard  11043:   /*tml = *localtime(&start_time.tm_sec);*/
                   11044:   /* strcpy(strstart,asctime(&tml)); */
                   11045:   strcpy(strstart,asctime(&start_time));
1.126     brouard  11046: 
                   11047: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  11048: /*  tp.tm_sec = tp.tm_sec +86400; */
                   11049: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  11050: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   11051: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   11052: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  11053: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  11054: /*   strt=asctime(&tmg); */
                   11055: /*   printf("Time(after) =%s",strstart);  */
                   11056: /*  (void) time (&time_value);
                   11057: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   11058: *  tm = *localtime(&time_value);
                   11059: *  strstart=asctime(&tm);
                   11060: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   11061: */
                   11062: 
                   11063:   nberr=0; /* Number of errors and warnings */
                   11064:   nbwarn=0;
1.184     brouard  11065: #ifdef WIN32
                   11066:   _getcwd(pathcd, size);
                   11067: #else
1.126     brouard  11068:   getcwd(pathcd, size);
1.184     brouard  11069: #endif
1.191     brouard  11070:   syscompilerinfo(0);
1.196     brouard  11071:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  11072:   if(argc <=1){
                   11073:     printf("\nEnter the parameter file name: ");
1.205     brouard  11074:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   11075:       printf("ERROR Empty parameter file name\n");
                   11076:       goto end;
                   11077:     }
1.126     brouard  11078:     i=strlen(pathr);
                   11079:     if(pathr[i-1]=='\n')
                   11080:       pathr[i-1]='\0';
1.156     brouard  11081:     i=strlen(pathr);
1.205     brouard  11082:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  11083:       pathr[i-1]='\0';
1.205     brouard  11084:     }
                   11085:     i=strlen(pathr);
                   11086:     if( i==0 ){
                   11087:       printf("ERROR Empty parameter file name\n");
                   11088:       goto end;
                   11089:     }
                   11090:     for (tok = pathr; tok != NULL; ){
1.126     brouard  11091:       printf("Pathr |%s|\n",pathr);
                   11092:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   11093:       printf("val= |%s| pathr=%s\n",val,pathr);
                   11094:       strcpy (pathtot, val);
                   11095:       if(pathr[0] == '\0') break; /* Dirty */
                   11096:     }
                   11097:   }
1.281     brouard  11098:   else if (argc<=2){
                   11099:     strcpy(pathtot,argv[1]);
                   11100:   }
1.126     brouard  11101:   else{
                   11102:     strcpy(pathtot,argv[1]);
1.281     brouard  11103:     strcpy(z,argv[2]);
                   11104:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  11105:   }
                   11106:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   11107:   /*cygwin_split_path(pathtot,path,optionfile);
                   11108:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   11109:   /* cutv(path,optionfile,pathtot,'\\');*/
                   11110: 
                   11111:   /* Split argv[0], imach program to get pathimach */
                   11112:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   11113:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11114:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11115:  /*   strcpy(pathimach,argv[0]); */
                   11116:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   11117:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   11118:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  11119: #ifdef WIN32
                   11120:   _chdir(path); /* Can be a relative path */
                   11121:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   11122: #else
1.126     brouard  11123:   chdir(path); /* Can be a relative path */
1.184     brouard  11124:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   11125: #endif
                   11126:   printf("Current directory %s!\n",pathcd);
1.126     brouard  11127:   strcpy(command,"mkdir ");
                   11128:   strcat(command,optionfilefiname);
                   11129:   if((outcmd=system(command)) != 0){
1.169     brouard  11130:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  11131:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   11132:     /* fclose(ficlog); */
                   11133: /*     exit(1); */
                   11134:   }
                   11135: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   11136: /*     perror("mkdir"); */
                   11137: /*   } */
                   11138: 
                   11139:   /*-------- arguments in the command line --------*/
                   11140: 
1.186     brouard  11141:   /* Main Log file */
1.126     brouard  11142:   strcat(filelog, optionfilefiname);
                   11143:   strcat(filelog,".log");    /* */
                   11144:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   11145:     printf("Problem with logfile %s\n",filelog);
                   11146:     goto end;
                   11147:   }
                   11148:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  11149:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  11150:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   11151:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   11152:  path=%s \n\
                   11153:  optionfile=%s\n\
                   11154:  optionfilext=%s\n\
1.156     brouard  11155:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  11156: 
1.197     brouard  11157:   syscompilerinfo(1);
1.167     brouard  11158: 
1.126     brouard  11159:   printf("Local time (at start):%s",strstart);
                   11160:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   11161:   fflush(ficlog);
                   11162: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  11163: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  11164: 
                   11165:   /* */
                   11166:   strcpy(fileres,"r");
                   11167:   strcat(fileres, optionfilefiname);
1.201     brouard  11168:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  11169:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  11170:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  11171: 
1.186     brouard  11172:   /* Main ---------arguments file --------*/
1.126     brouard  11173: 
                   11174:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  11175:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   11176:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  11177:     fflush(ficlog);
1.149     brouard  11178:     /* goto end; */
                   11179:     exit(70); 
1.126     brouard  11180:   }
                   11181: 
                   11182:   strcpy(filereso,"o");
1.201     brouard  11183:   strcat(filereso,fileresu);
1.126     brouard  11184:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   11185:     printf("Problem with Output resultfile: %s\n", filereso);
                   11186:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   11187:     fflush(ficlog);
                   11188:     goto end;
                   11189:   }
1.278     brouard  11190:       /*-------- Rewriting parameter file ----------*/
                   11191:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   11192:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   11193:   strcat(rfileres,".");    /* */
                   11194:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11195:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   11196:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11197:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   11198:     fflush(ficlog);
                   11199:     goto end;
                   11200:   }
                   11201:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  11202: 
1.278     brouard  11203:                                      
1.126     brouard  11204:   /* Reads comments: lines beginning with '#' */
                   11205:   numlinepar=0;
1.277     brouard  11206:   /* Is it a BOM UTF-8 Windows file? */
                   11207:   /* First parameter line */
1.197     brouard  11208:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11209:     noffset=0;
                   11210:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11211:     {
                   11212:       noffset=noffset+3;
                   11213:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11214:     }
1.302     brouard  11215: /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   11216:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
1.277     brouard  11217:     {
                   11218:       noffset=noffset+2;
                   11219:       printf("# File is an UTF16BE BOM file\n");
                   11220:     }
                   11221:     else if( line[0] == 0 && line[1] == 0)
                   11222:     {
                   11223:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11224:        noffset=noffset+4;
                   11225:        printf("# File is an UTF16BE BOM file\n");
                   11226:       }
                   11227:     } else{
                   11228:       ;/*printf(" Not a BOM file\n");*/
                   11229:     }
                   11230:   
1.197     brouard  11231:     /* If line starts with a # it is a comment */
1.277     brouard  11232:     if (line[noffset] == '#') {
1.197     brouard  11233:       numlinepar++;
                   11234:       fputs(line,stdout);
                   11235:       fputs(line,ficparo);
1.278     brouard  11236:       fputs(line,ficres);
1.197     brouard  11237:       fputs(line,ficlog);
                   11238:       continue;
                   11239:     }else
                   11240:       break;
                   11241:   }
                   11242:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11243:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11244:     if (num_filled != 5) {
                   11245:       printf("Should be 5 parameters\n");
1.283     brouard  11246:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11247:     }
1.126     brouard  11248:     numlinepar++;
1.197     brouard  11249:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11250:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11251:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11252:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11253:   }
                   11254:   /* Second parameter line */
                   11255:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11256:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11257:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11258:     if (line[0] == '#') {
                   11259:       numlinepar++;
1.283     brouard  11260:       printf("%s",line);
                   11261:       fprintf(ficres,"%s",line);
                   11262:       fprintf(ficparo,"%s",line);
                   11263:       fprintf(ficlog,"%s",line);
1.197     brouard  11264:       continue;
                   11265:     }else
                   11266:       break;
                   11267:   }
1.223     brouard  11268:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11269:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11270:     if (num_filled != 11) {
                   11271:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11272:       printf("but line=%s\n",line);
1.283     brouard  11273:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11274:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11275:     }
1.286     brouard  11276:     if( lastpass > maxwav){
                   11277:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11278:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11279:       fflush(ficlog);
                   11280:       goto end;
                   11281:     }
                   11282:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11283:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11284:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11285:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11286:   }
1.203     brouard  11287:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11288:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11289:   /* Third parameter line */
                   11290:   while(fgets(line, MAXLINE, ficpar)) {
                   11291:     /* If line starts with a # it is a comment */
                   11292:     if (line[0] == '#') {
                   11293:       numlinepar++;
1.283     brouard  11294:       printf("%s",line);
                   11295:       fprintf(ficres,"%s",line);
                   11296:       fprintf(ficparo,"%s",line);
                   11297:       fprintf(ficlog,"%s",line);
1.197     brouard  11298:       continue;
                   11299:     }else
                   11300:       break;
                   11301:   }
1.201     brouard  11302:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11303:     if (num_filled != 1){
1.302     brouard  11304:       printf("ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
                   11305:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
1.197     brouard  11306:       model[0]='\0';
                   11307:       goto end;
                   11308:     }
                   11309:     else{
                   11310:       if (model[0]=='+'){
                   11311:        for(i=1; i<=strlen(model);i++)
                   11312:          modeltemp[i-1]=model[i];
1.201     brouard  11313:        strcpy(model,modeltemp); 
1.197     brouard  11314:       }
                   11315:     }
1.199     brouard  11316:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11317:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11318:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11319:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11320:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11321:   }
                   11322:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11323:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11324:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11325:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11326:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11327:   fflush(ficlog);
1.190     brouard  11328:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11329:   if(model[0]=='#'){
1.279     brouard  11330:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11331:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11332:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11333:     if(mle != -1){
1.279     brouard  11334:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11335:       exit(1);
                   11336:     }
                   11337:   }
1.126     brouard  11338:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11339:     ungetc(c,ficpar);
                   11340:     fgets(line, MAXLINE, ficpar);
                   11341:     numlinepar++;
1.195     brouard  11342:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11343:       z[0]=line[1];
                   11344:     }
                   11345:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11346:     fputs(line, stdout);
                   11347:     //puts(line);
1.126     brouard  11348:     fputs(line,ficparo);
                   11349:     fputs(line,ficlog);
                   11350:   }
                   11351:   ungetc(c,ficpar);
                   11352: 
                   11353:    
1.290     brouard  11354:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11355:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11356:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11357:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11358:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11359:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11360:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11361:   */
                   11362:   if (strlen(model)>1) 
1.187     brouard  11363:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11364:   else
1.187     brouard  11365:     ncovmodel=2; /* Constant and age */
1.133     brouard  11366:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11367:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11368:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11369:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11370:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11371:     fflush(stdout);
                   11372:     fclose (ficlog);
                   11373:     goto end;
                   11374:   }
1.126     brouard  11375:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11376:   delti=delti3[1][1];
                   11377:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11378:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11379: /* We could also provide initial parameters values giving by simple logistic regression 
                   11380:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11381:       /* for(i=1;i<nlstate;i++){ */
                   11382:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11383:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11384:       /* } */
1.126     brouard  11385:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11386:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11387:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11388:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11389:     fclose (ficparo);
                   11390:     fclose (ficlog);
                   11391:     goto end;
                   11392:     exit(0);
1.220     brouard  11393:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11394:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11395:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11396:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11397:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11398:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11399:     hess=matrix(1,npar,1,npar);
1.220     brouard  11400:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11401:     /* Read guessed parameters */
1.126     brouard  11402:     /* Reads comments: lines beginning with '#' */
                   11403:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11404:       ungetc(c,ficpar);
                   11405:       fgets(line, MAXLINE, ficpar);
                   11406:       numlinepar++;
1.141     brouard  11407:       fputs(line,stdout);
1.126     brouard  11408:       fputs(line,ficparo);
                   11409:       fputs(line,ficlog);
                   11410:     }
                   11411:     ungetc(c,ficpar);
                   11412:     
                   11413:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11414:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11415:     for(i=1; i <=nlstate; i++){
1.234     brouard  11416:       j=0;
1.126     brouard  11417:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11418:        if(jj==i) continue;
                   11419:        j++;
1.292     brouard  11420:        while((c=getc(ficpar))=='#' && c!= EOF){
                   11421:          ungetc(c,ficpar);
                   11422:          fgets(line, MAXLINE, ficpar);
                   11423:          numlinepar++;
                   11424:          fputs(line,stdout);
                   11425:          fputs(line,ficparo);
                   11426:          fputs(line,ficlog);
                   11427:        }
                   11428:        ungetc(c,ficpar);
1.234     brouard  11429:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11430:        if ((i1 != i) || (j1 != jj)){
                   11431:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11432: It might be a problem of design; if ncovcol and the model are correct\n \
                   11433: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11434:          exit(1);
                   11435:        }
                   11436:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11437:        if(mle==1)
                   11438:          printf("%1d%1d",i,jj);
                   11439:        fprintf(ficlog,"%1d%1d",i,jj);
                   11440:        for(k=1; k<=ncovmodel;k++){
                   11441:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11442:          if(mle==1){
                   11443:            printf(" %lf",param[i][j][k]);
                   11444:            fprintf(ficlog," %lf",param[i][j][k]);
                   11445:          }
                   11446:          else
                   11447:            fprintf(ficlog," %lf",param[i][j][k]);
                   11448:          fprintf(ficparo," %lf",param[i][j][k]);
                   11449:        }
                   11450:        fscanf(ficpar,"\n");
                   11451:        numlinepar++;
                   11452:        if(mle==1)
                   11453:          printf("\n");
                   11454:        fprintf(ficlog,"\n");
                   11455:        fprintf(ficparo,"\n");
1.126     brouard  11456:       }
                   11457:     }  
                   11458:     fflush(ficlog);
1.234     brouard  11459:     
1.251     brouard  11460:     /* Reads parameters values */
1.126     brouard  11461:     p=param[1][1];
1.251     brouard  11462:     pstart=paramstart[1][1];
1.126     brouard  11463:     
                   11464:     /* Reads comments: lines beginning with '#' */
                   11465:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11466:       ungetc(c,ficpar);
                   11467:       fgets(line, MAXLINE, ficpar);
                   11468:       numlinepar++;
1.141     brouard  11469:       fputs(line,stdout);
1.126     brouard  11470:       fputs(line,ficparo);
                   11471:       fputs(line,ficlog);
                   11472:     }
                   11473:     ungetc(c,ficpar);
                   11474: 
                   11475:     for(i=1; i <=nlstate; i++){
                   11476:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11477:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11478:        if ( (i1-i) * (j1-j) != 0){
                   11479:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11480:          exit(1);
                   11481:        }
                   11482:        printf("%1d%1d",i,j);
                   11483:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11484:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11485:        for(k=1; k<=ncovmodel;k++){
                   11486:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11487:          printf(" %le",delti3[i][j][k]);
                   11488:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11489:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11490:        }
                   11491:        fscanf(ficpar,"\n");
                   11492:        numlinepar++;
                   11493:        printf("\n");
                   11494:        fprintf(ficparo,"\n");
                   11495:        fprintf(ficlog,"\n");
1.126     brouard  11496:       }
                   11497:     }
                   11498:     fflush(ficlog);
1.234     brouard  11499:     
1.145     brouard  11500:     /* Reads covariance matrix */
1.126     brouard  11501:     delti=delti3[1][1];
1.220     brouard  11502:                
                   11503:                
1.126     brouard  11504:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11505:                
1.126     brouard  11506:     /* Reads comments: lines beginning with '#' */
                   11507:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11508:       ungetc(c,ficpar);
                   11509:       fgets(line, MAXLINE, ficpar);
                   11510:       numlinepar++;
1.141     brouard  11511:       fputs(line,stdout);
1.126     brouard  11512:       fputs(line,ficparo);
                   11513:       fputs(line,ficlog);
                   11514:     }
                   11515:     ungetc(c,ficpar);
1.220     brouard  11516:                
1.126     brouard  11517:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11518:     hess=matrix(1,npar,1,npar);
1.131     brouard  11519:     for(i=1; i <=npar; i++)
                   11520:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11521:                
1.194     brouard  11522:     /* Scans npar lines */
1.126     brouard  11523:     for(i=1; i <=npar; i++){
1.226     brouard  11524:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11525:       if(count != 3){
1.226     brouard  11526:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11527: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11528: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11529:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11530: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11531: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11532:        exit(1);
1.220     brouard  11533:       }else{
1.226     brouard  11534:        if(mle==1)
                   11535:          printf("%1d%1d%d",i1,j1,jk);
                   11536:       }
                   11537:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11538:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11539:       for(j=1; j <=i; j++){
1.226     brouard  11540:        fscanf(ficpar," %le",&matcov[i][j]);
                   11541:        if(mle==1){
                   11542:          printf(" %.5le",matcov[i][j]);
                   11543:        }
                   11544:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11545:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11546:       }
                   11547:       fscanf(ficpar,"\n");
                   11548:       numlinepar++;
                   11549:       if(mle==1)
1.220     brouard  11550:                                printf("\n");
1.126     brouard  11551:       fprintf(ficlog,"\n");
                   11552:       fprintf(ficparo,"\n");
                   11553:     }
1.194     brouard  11554:     /* End of read covariance matrix npar lines */
1.126     brouard  11555:     for(i=1; i <=npar; i++)
                   11556:       for(j=i+1;j<=npar;j++)
1.226     brouard  11557:        matcov[i][j]=matcov[j][i];
1.126     brouard  11558:     
                   11559:     if(mle==1)
                   11560:       printf("\n");
                   11561:     fprintf(ficlog,"\n");
                   11562:     
                   11563:     fflush(ficlog);
                   11564:     
                   11565:   }    /* End of mle != -3 */
1.218     brouard  11566:   
1.186     brouard  11567:   /*  Main data
                   11568:    */
1.290     brouard  11569:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11570:   /* num=lvector(1,n); */
                   11571:   /* moisnais=vector(1,n); */
                   11572:   /* annais=vector(1,n); */
                   11573:   /* moisdc=vector(1,n); */
                   11574:   /* andc=vector(1,n); */
                   11575:   /* weight=vector(1,n); */
                   11576:   /* agedc=vector(1,n); */
                   11577:   /* cod=ivector(1,n); */
                   11578:   /* for(i=1;i<=n;i++){ */
                   11579:   num=lvector(firstobs,lastobs);
                   11580:   moisnais=vector(firstobs,lastobs);
                   11581:   annais=vector(firstobs,lastobs);
                   11582:   moisdc=vector(firstobs,lastobs);
                   11583:   andc=vector(firstobs,lastobs);
                   11584:   weight=vector(firstobs,lastobs);
                   11585:   agedc=vector(firstobs,lastobs);
                   11586:   cod=ivector(firstobs,lastobs);
                   11587:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11588:     num[i]=0;
                   11589:     moisnais[i]=0;
                   11590:     annais[i]=0;
                   11591:     moisdc[i]=0;
                   11592:     andc[i]=0;
                   11593:     agedc[i]=0;
                   11594:     cod[i]=0;
                   11595:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11596:   }
1.290     brouard  11597:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11598:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11599:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11600:   tab=ivector(1,NCOVMAX);
1.144     brouard  11601:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11602:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11603: 
1.136     brouard  11604:   /* Reads data from file datafile */
                   11605:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11606:     goto end;
                   11607: 
                   11608:   /* Calculation of the number of parameters from char model */
1.234     brouard  11609:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11610:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11611:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11612:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11613:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11614:   */
                   11615:   
                   11616:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11617:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11618:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11619:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11620:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11621:   TvarF=ivector(1,NCOVMAX); /*  */
                   11622:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11623:   TvarV=ivector(1,NCOVMAX); /*  */
                   11624:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11625:   TvarA=ivector(1,NCOVMAX); /*  */
                   11626:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11627:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11628:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11629:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11630:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11631:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11632:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11633:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11634:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11635: 
1.230     brouard  11636:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11637:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11638:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11639:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11640:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11641:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11642:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11643:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11644:   */
                   11645:   /* For model-covariate k tells which data-covariate to use but
                   11646:     because this model-covariate is a construction we invent a new column
                   11647:     ncovcol + k1
                   11648:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11649:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11650:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11651:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11652:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11653:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11654:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11655:   */
1.145     brouard  11656:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11657:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11658:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11659:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11660:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11661:                         4 covariates (3 plus signs)
                   11662:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11663:                      */  
1.230     brouard  11664:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11665:                                * individual dummy, fixed or varying:
                   11666:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11667:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11668:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11669:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11670:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11671:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11672:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11673:                                * individual quantitative, fixed or varying:
                   11674:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11675:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11676:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11677: /* Main decodemodel */
                   11678: 
1.187     brouard  11679: 
1.223     brouard  11680:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11681:     goto end;
                   11682: 
1.137     brouard  11683:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11684:     nbwarn++;
                   11685:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11686:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11687:   }
1.136     brouard  11688:     /*  if(mle==1){*/
1.137     brouard  11689:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11690:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11691:   }
                   11692: 
                   11693:     /*-calculation of age at interview from date of interview and age at death -*/
                   11694:   agev=matrix(1,maxwav,1,imx);
                   11695: 
                   11696:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11697:     goto end;
                   11698: 
1.126     brouard  11699: 
1.136     brouard  11700:   agegomp=(int)agemin;
1.290     brouard  11701:   free_vector(moisnais,firstobs,lastobs);
                   11702:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11703:   /* free_matrix(mint,1,maxwav,1,n);
                   11704:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11705:   /* free_vector(moisdc,1,n); */
                   11706:   /* free_vector(andc,1,n); */
1.145     brouard  11707:   /* */
                   11708:   
1.126     brouard  11709:   wav=ivector(1,imx);
1.214     brouard  11710:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11711:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11712:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11713:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11714:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11715:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11716:    
                   11717:   /* Concatenates waves */
1.214     brouard  11718:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11719:      Death is a valid wave (if date is known).
                   11720:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11721:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11722:      and mw[mi+1][i]. dh depends on stepm.
                   11723:   */
                   11724: 
1.126     brouard  11725:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11726:   /* Concatenates waves */
1.145     brouard  11727:  
1.290     brouard  11728:   free_vector(moisdc,firstobs,lastobs);
                   11729:   free_vector(andc,firstobs,lastobs);
1.215     brouard  11730: 
1.126     brouard  11731:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11732:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11733:   ncodemax[1]=1;
1.145     brouard  11734:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11735:   cptcoveff=0;
1.220     brouard  11736:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11737:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11738:   }
                   11739:   
                   11740:   ncovcombmax=pow(2,cptcoveff);
                   11741:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11742:   for(i=1;i<ncovcombmax;i++)
                   11743:     invalidvarcomb[i]=0;
                   11744:   
1.211     brouard  11745:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11746:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11747:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11748:   
1.200     brouard  11749:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11750:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11751:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11752:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11753:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11754:    * (currently 0 or 1) in the data.
                   11755:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11756:    * corresponding modality (h,j).
                   11757:    */
                   11758: 
1.145     brouard  11759:   h=0;
                   11760:   /*if (cptcovn > 0) */
1.126     brouard  11761:   m=pow(2,cptcoveff);
                   11762:  
1.144     brouard  11763:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11764:           * For k=4 covariates, h goes from 1 to m=2**k
                   11765:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11766:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11767:           *     h\k   1     2     3     4
1.143     brouard  11768:           *______________________________  
                   11769:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11770:           *     2     2     1     1     1
                   11771:           *     3 i=2 1     2     1     1
                   11772:           *     4     2     2     1     1
                   11773:           *     5 i=3 1 i=2 1     2     1
                   11774:           *     6     2     1     2     1
                   11775:           *     7 i=4 1     2     2     1
                   11776:           *     8     2     2     2     1
1.197     brouard  11777:           *     9 i=5 1 i=3 1 i=2 1     2
                   11778:           *    10     2     1     1     2
                   11779:           *    11 i=6 1     2     1     2
                   11780:           *    12     2     2     1     2
                   11781:           *    13 i=7 1 i=4 1     2     2    
                   11782:           *    14     2     1     2     2
                   11783:           *    15 i=8 1     2     2     2
                   11784:           *    16     2     2     2     2
1.143     brouard  11785:           */
1.212     brouard  11786:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11787:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11788:      * and the value of each covariate?
                   11789:      * V1=1, V2=1, V3=2, V4=1 ?
                   11790:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11791:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11792:      * In order to get the real value in the data, we use nbcode
                   11793:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11794:      * We are keeping this crazy system in order to be able (in the future?) 
                   11795:      * to have more than 2 values (0 or 1) for a covariate.
                   11796:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11797:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11798:      *              bbbbbbbb
                   11799:      *              76543210     
                   11800:      *   h-1        00000101 (6-1=5)
1.219     brouard  11801:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11802:      *           &
                   11803:      *     1        00000001 (1)
1.219     brouard  11804:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11805:      *          +1= 00000001 =1 
1.211     brouard  11806:      *
                   11807:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11808:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11809:      *    >>k'            11
                   11810:      *          &   00000001
                   11811:      *            = 00000001
                   11812:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11813:      * Reverse h=6 and m=16?
                   11814:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11815:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11816:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11817:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11818:      * V3=decodtabm(14,3,2**4)=2
                   11819:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11820:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11821:      *          &1 000000001
                   11822:      *           = 000000001
                   11823:      *         +1= 000000010 =2
                   11824:      *                  2211
                   11825:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11826:      *                  V3=2
1.220     brouard  11827:                 * codtabm and decodtabm are identical
1.211     brouard  11828:      */
                   11829: 
1.145     brouard  11830: 
                   11831:  free_ivector(Ndum,-1,NCOVMAX);
                   11832: 
                   11833: 
1.126     brouard  11834:     
1.186     brouard  11835:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11836:   strcpy(optionfilegnuplot,optionfilefiname);
                   11837:   if(mle==-3)
1.201     brouard  11838:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11839:   strcat(optionfilegnuplot,".gp");
                   11840: 
                   11841:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11842:     printf("Problem with file %s",optionfilegnuplot);
                   11843:   }
                   11844:   else{
1.204     brouard  11845:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11846:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11847:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11848:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11849:   }
                   11850:   /*  fclose(ficgp);*/
1.186     brouard  11851: 
                   11852: 
                   11853:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11854: 
                   11855:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11856:   if(mle==-3)
1.201     brouard  11857:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11858:   strcat(optionfilehtm,".htm");
                   11859:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11860:     printf("Problem with %s \n",optionfilehtm);
                   11861:     exit(0);
1.126     brouard  11862:   }
                   11863: 
                   11864:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11865:   strcat(optionfilehtmcov,"-cov.htm");
                   11866:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11867:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11868:   }
                   11869:   else{
                   11870:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11871: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11872: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11873:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11874:   }
                   11875: 
1.213     brouard  11876:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11877: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11878: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11879: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11880: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11881: \n\
                   11882: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11883:  <ul><li><h4>Parameter files</h4>\n\
                   11884:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11885:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11886:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11887:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11888:  - Date and time at start: %s</ul>\n",\
                   11889:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11890:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11891:          fileres,fileres,\
                   11892:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11893:   fflush(fichtm);
                   11894: 
                   11895:   strcpy(pathr,path);
                   11896:   strcat(pathr,optionfilefiname);
1.184     brouard  11897: #ifdef WIN32
                   11898:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11899: #else
1.126     brouard  11900:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11901: #endif
                   11902:          
1.126     brouard  11903:   
1.220     brouard  11904:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11905:                 and for any valid combination of covariates
1.126     brouard  11906:      and prints on file fileres'p'. */
1.251     brouard  11907:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11908:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11909: 
                   11910:   fprintf(fichtm,"\n");
1.286     brouard  11911:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11912:          ftol, stepm);
                   11913:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11914:   ncurrv=1;
                   11915:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11916:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11917:   ncurrv=i;
                   11918:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11919:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  11920:   ncurrv=i;
                   11921:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11922:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  11923:   ncurrv=i;
                   11924:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11925:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11926:           nlstate, ndeath, maxwav, mle, weightopt);
                   11927: 
                   11928:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11929: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11930: 
                   11931:   
                   11932:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11933: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11934: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11935:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11936:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11937:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11938:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11939:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11940:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11941: 
1.126     brouard  11942:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11943:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11944:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11945: 
                   11946:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11947:   /* For mortality only */
1.126     brouard  11948:   if (mle==-3){
1.136     brouard  11949:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11950:     for(i=1;i<=NDIM;i++)
                   11951:       for(j=1;j<=NDIM;j++)
                   11952:        ximort[i][j]=0.;
1.186     brouard  11953:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  11954:     cens=ivector(firstobs,lastobs);
                   11955:     ageexmed=vector(firstobs,lastobs);
                   11956:     agecens=vector(firstobs,lastobs);
                   11957:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  11958:                
1.126     brouard  11959:     for (i=1; i<=imx; i++){
                   11960:       dcwave[i]=-1;
                   11961:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11962:        if (s[m][i]>nlstate) {
                   11963:          dcwave[i]=m;
                   11964:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11965:          break;
                   11966:        }
1.126     brouard  11967:     }
1.226     brouard  11968:     
1.126     brouard  11969:     for (i=1; i<=imx; i++) {
                   11970:       if (wav[i]>0){
1.226     brouard  11971:        ageexmed[i]=agev[mw[1][i]][i];
                   11972:        j=wav[i];
                   11973:        agecens[i]=1.; 
                   11974:        
                   11975:        if (ageexmed[i]> 1 && wav[i] > 0){
                   11976:          agecens[i]=agev[mw[j][i]][i];
                   11977:          cens[i]= 1;
                   11978:        }else if (ageexmed[i]< 1) 
                   11979:          cens[i]= -1;
                   11980:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   11981:          cens[i]=0 ;
1.126     brouard  11982:       }
                   11983:       else cens[i]=-1;
                   11984:     }
                   11985:     
                   11986:     for (i=1;i<=NDIM;i++) {
                   11987:       for (j=1;j<=NDIM;j++)
1.226     brouard  11988:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  11989:     }
                   11990:     
1.302     brouard  11991:     p[1]=0.0268; p[NDIM]=0.083;
                   11992:     /* printf("%lf %lf", p[1], p[2]); */
1.126     brouard  11993:     
                   11994:     
1.136     brouard  11995: #ifdef GSL
                   11996:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  11997: #else
1.126     brouard  11998:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  11999: #endif
1.201     brouard  12000:     strcpy(filerespow,"POW-MORT_"); 
                   12001:     strcat(filerespow,fileresu);
1.126     brouard  12002:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   12003:       printf("Problem with resultfile: %s\n", filerespow);
                   12004:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   12005:     }
1.136     brouard  12006: #ifdef GSL
                   12007:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  12008: #else
1.126     brouard  12009:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  12010: #endif
1.126     brouard  12011:     /*  for (i=1;i<=nlstate;i++)
                   12012:        for(j=1;j<=nlstate+ndeath;j++)
                   12013:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   12014:     */
                   12015:     fprintf(ficrespow,"\n");
1.136     brouard  12016: #ifdef GSL
                   12017:     /* gsl starts here */ 
                   12018:     T = gsl_multimin_fminimizer_nmsimplex;
                   12019:     gsl_multimin_fminimizer *sfm = NULL;
                   12020:     gsl_vector *ss, *x;
                   12021:     gsl_multimin_function minex_func;
                   12022: 
                   12023:     /* Initial vertex size vector */
                   12024:     ss = gsl_vector_alloc (NDIM);
                   12025:     
                   12026:     if (ss == NULL){
                   12027:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   12028:     }
                   12029:     /* Set all step sizes to 1 */
                   12030:     gsl_vector_set_all (ss, 0.001);
                   12031: 
                   12032:     /* Starting point */
1.126     brouard  12033:     
1.136     brouard  12034:     x = gsl_vector_alloc (NDIM);
                   12035:     
                   12036:     if (x == NULL){
                   12037:       gsl_vector_free(ss);
                   12038:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   12039:     }
                   12040:   
                   12041:     /* Initialize method and iterate */
                   12042:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  12043:     /*     gsl_vector_set(x, 0, 0.0268); */
                   12044:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  12045:     gsl_vector_set(x, 0, p[1]);
                   12046:     gsl_vector_set(x, 1, p[2]);
                   12047: 
                   12048:     minex_func.f = &gompertz_f;
                   12049:     minex_func.n = NDIM;
                   12050:     minex_func.params = (void *)&p; /* ??? */
                   12051:     
                   12052:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   12053:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   12054:     
                   12055:     printf("Iterations beginning .....\n\n");
                   12056:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   12057: 
                   12058:     iteri=0;
                   12059:     while (rval == GSL_CONTINUE){
                   12060:       iteri++;
                   12061:       status = gsl_multimin_fminimizer_iterate(sfm);
                   12062:       
                   12063:       if (status) printf("error: %s\n", gsl_strerror (status));
                   12064:       fflush(0);
                   12065:       
                   12066:       if (status) 
                   12067:         break;
                   12068:       
                   12069:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   12070:       ssval = gsl_multimin_fminimizer_size (sfm);
                   12071:       
                   12072:       if (rval == GSL_SUCCESS)
                   12073:         printf ("converged to a local maximum at\n");
                   12074:       
                   12075:       printf("%5d ", iteri);
                   12076:       for (it = 0; it < NDIM; it++){
                   12077:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   12078:       }
                   12079:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   12080:     }
                   12081:     
                   12082:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   12083:     
                   12084:     gsl_vector_free(x); /* initial values */
                   12085:     gsl_vector_free(ss); /* inital step size */
                   12086:     for (it=0; it<NDIM; it++){
                   12087:       p[it+1]=gsl_vector_get(sfm->x,it);
                   12088:       fprintf(ficrespow," %.12lf", p[it]);
                   12089:     }
                   12090:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   12091: #endif
                   12092: #ifdef POWELL
                   12093:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   12094: #endif  
1.126     brouard  12095:     fclose(ficrespow);
                   12096:     
1.203     brouard  12097:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  12098: 
                   12099:     for(i=1; i <=NDIM; i++)
                   12100:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  12101:                                matcov[i][j]=matcov[j][i];
1.126     brouard  12102:     
                   12103:     printf("\nCovariance matrix\n ");
1.203     brouard  12104:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  12105:     for(i=1; i <=NDIM; i++) {
                   12106:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  12107:                                printf("%f ",matcov[i][j]);
                   12108:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  12109:       }
1.203     brouard  12110:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  12111:     }
                   12112:     
                   12113:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  12114:     for (i=1;i<=NDIM;i++) {
1.126     brouard  12115:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  12116:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   12117:     }
1.302     brouard  12118:     lsurv=vector(agegomp,AGESUP);
                   12119:     lpop=vector(agegomp,AGESUP);
                   12120:     tpop=vector(agegomp,AGESUP);
1.126     brouard  12121:     lsurv[agegomp]=100000;
                   12122:     
                   12123:     for (k=agegomp;k<=AGESUP;k++) {
                   12124:       agemortsup=k;
                   12125:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   12126:     }
                   12127:     
                   12128:     for (k=agegomp;k<agemortsup;k++)
                   12129:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   12130:     
                   12131:     for (k=agegomp;k<agemortsup;k++){
                   12132:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   12133:       sumlpop=sumlpop+lpop[k];
                   12134:     }
                   12135:     
                   12136:     tpop[agegomp]=sumlpop;
                   12137:     for (k=agegomp;k<(agemortsup-3);k++){
                   12138:       /*  tpop[k+1]=2;*/
                   12139:       tpop[k+1]=tpop[k]-lpop[k];
                   12140:     }
                   12141:     
                   12142:     
                   12143:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   12144:     for (k=agegomp;k<(agemortsup-2);k++) 
                   12145:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   12146:     
                   12147:     
                   12148:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  12149:                ageminpar=50;
                   12150:                agemaxpar=100;
1.194     brouard  12151:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   12152:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12153: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12154: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   12155:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12156: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12157: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12158:     }else{
                   12159:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   12160:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  12161:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  12162:                }
1.201     brouard  12163:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  12164:                     stepm, weightopt,\
                   12165:                     model,imx,p,matcov,agemortsup);
                   12166:     
1.302     brouard  12167:     free_vector(lsurv,agegomp,AGESUP);
                   12168:     free_vector(lpop,agegomp,AGESUP);
                   12169:     free_vector(tpop,agegomp,AGESUP);
1.220     brouard  12170:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  12171:     free_ivector(dcwave,firstobs,lastobs);
                   12172:     free_vector(agecens,firstobs,lastobs);
                   12173:     free_vector(ageexmed,firstobs,lastobs);
                   12174:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  12175: #ifdef GSL
1.136     brouard  12176: #endif
1.186     brouard  12177:   } /* Endof if mle==-3 mortality only */
1.205     brouard  12178:   /* Standard  */
                   12179:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   12180:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12181:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  12182:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  12183:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12184:     for (k=1; k<=npar;k++)
                   12185:       printf(" %d %8.5f",k,p[k]);
                   12186:     printf("\n");
1.205     brouard  12187:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   12188:       /* mlikeli uses func not funcone */
1.247     brouard  12189:       /* for(i=1;i<nlstate;i++){ */
                   12190:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   12191:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   12192:       /* } */
1.205     brouard  12193:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   12194:     }
                   12195:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   12196:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12197:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   12198:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12199:     }
                   12200:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  12201:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12202:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12203:     for (k=1; k<=npar;k++)
                   12204:       printf(" %d %8.5f",k,p[k]);
                   12205:     printf("\n");
                   12206:     
                   12207:     /*--------- results files --------------*/
1.283     brouard  12208:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12209:     
                   12210:     
                   12211:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12212:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12213:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12214:     for(i=1,jk=1; i <=nlstate; i++){
                   12215:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12216:        if (k != i) {
                   12217:          printf("%d%d ",i,k);
                   12218:          fprintf(ficlog,"%d%d ",i,k);
                   12219:          fprintf(ficres,"%1d%1d ",i,k);
                   12220:          for(j=1; j <=ncovmodel; j++){
                   12221:            printf("%12.7f ",p[jk]);
                   12222:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12223:            fprintf(ficres,"%12.7f ",p[jk]);
                   12224:            jk++; 
                   12225:          }
                   12226:          printf("\n");
                   12227:          fprintf(ficlog,"\n");
                   12228:          fprintf(ficres,"\n");
                   12229:        }
1.126     brouard  12230:       }
                   12231:     }
1.203     brouard  12232:     if(mle != 0){
                   12233:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12234:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12235:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12236:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12237:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12238:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12239:        for(k=1; k <=(nlstate+ndeath); k++){
                   12240:          if (k != i) {
                   12241:            printf("%d%d ",i,k);
                   12242:            fprintf(ficlog,"%d%d ",i,k);
                   12243:            for(j=1; j <=ncovmodel; j++){
                   12244:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12245:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12246:              jk++; 
                   12247:            }
                   12248:            printf("\n");
                   12249:            fprintf(ficlog,"\n");
                   12250:          }
                   12251:        }
1.193     brouard  12252:       }
1.203     brouard  12253:     } /* end of hesscov and Wald tests */
1.225     brouard  12254:     
1.203     brouard  12255:     /*  */
1.126     brouard  12256:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12257:     printf("# Scales (for hessian or gradient estimation)\n");
                   12258:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12259:     for(i=1,jk=1; i <=nlstate; i++){
                   12260:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12261:        if (j!=i) {
                   12262:          fprintf(ficres,"%1d%1d",i,j);
                   12263:          printf("%1d%1d",i,j);
                   12264:          fprintf(ficlog,"%1d%1d",i,j);
                   12265:          for(k=1; k<=ncovmodel;k++){
                   12266:            printf(" %.5e",delti[jk]);
                   12267:            fprintf(ficlog," %.5e",delti[jk]);
                   12268:            fprintf(ficres," %.5e",delti[jk]);
                   12269:            jk++;
                   12270:          }
                   12271:          printf("\n");
                   12272:          fprintf(ficlog,"\n");
                   12273:          fprintf(ficres,"\n");
                   12274:        }
1.126     brouard  12275:       }
                   12276:     }
                   12277:     
                   12278:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12279:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12280:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12281:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12282:     /* # 121 Var(a12)\n\ */
                   12283:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12284:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12285:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12286:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12287:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12288:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12289:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12290:     
                   12291:     
                   12292:     /* Just to have a covariance matrix which will be more understandable
                   12293:        even is we still don't want to manage dictionary of variables
                   12294:     */
                   12295:     for(itimes=1;itimes<=2;itimes++){
                   12296:       jj=0;
                   12297:       for(i=1; i <=nlstate; i++){
1.225     brouard  12298:        for(j=1; j <=nlstate+ndeath; j++){
                   12299:          if(j==i) continue;
                   12300:          for(k=1; k<=ncovmodel;k++){
                   12301:            jj++;
                   12302:            ca[0]= k+'a'-1;ca[1]='\0';
                   12303:            if(itimes==1){
                   12304:              if(mle>=1)
                   12305:                printf("#%1d%1d%d",i,j,k);
                   12306:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12307:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12308:            }else{
                   12309:              if(mle>=1)
                   12310:                printf("%1d%1d%d",i,j,k);
                   12311:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12312:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12313:            }
                   12314:            ll=0;
                   12315:            for(li=1;li <=nlstate; li++){
                   12316:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12317:                if(lj==li) continue;
                   12318:                for(lk=1;lk<=ncovmodel;lk++){
                   12319:                  ll++;
                   12320:                  if(ll<=jj){
                   12321:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12322:                    if(ll<jj){
                   12323:                      if(itimes==1){
                   12324:                        if(mle>=1)
                   12325:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12326:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12327:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12328:                      }else{
                   12329:                        if(mle>=1)
                   12330:                          printf(" %.5e",matcov[jj][ll]); 
                   12331:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12332:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12333:                      }
                   12334:                    }else{
                   12335:                      if(itimes==1){
                   12336:                        if(mle>=1)
                   12337:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12338:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12339:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12340:                      }else{
                   12341:                        if(mle>=1)
                   12342:                          printf(" %.7e",matcov[jj][ll]); 
                   12343:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12344:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12345:                      }
                   12346:                    }
                   12347:                  }
                   12348:                } /* end lk */
                   12349:              } /* end lj */
                   12350:            } /* end li */
                   12351:            if(mle>=1)
                   12352:              printf("\n");
                   12353:            fprintf(ficlog,"\n");
                   12354:            fprintf(ficres,"\n");
                   12355:            numlinepar++;
                   12356:          } /* end k*/
                   12357:        } /*end j */
1.126     brouard  12358:       } /* end i */
                   12359:     } /* end itimes */
                   12360:     
                   12361:     fflush(ficlog);
                   12362:     fflush(ficres);
1.225     brouard  12363:     while(fgets(line, MAXLINE, ficpar)) {
                   12364:       /* If line starts with a # it is a comment */
                   12365:       if (line[0] == '#') {
                   12366:        numlinepar++;
                   12367:        fputs(line,stdout);
                   12368:        fputs(line,ficparo);
                   12369:        fputs(line,ficlog);
1.299     brouard  12370:        fputs(line,ficres);
1.225     brouard  12371:        continue;
                   12372:       }else
                   12373:        break;
                   12374:     }
                   12375:     
1.209     brouard  12376:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12377:     /*   ungetc(c,ficpar); */
                   12378:     /*   fgets(line, MAXLINE, ficpar); */
                   12379:     /*   fputs(line,stdout); */
                   12380:     /*   fputs(line,ficparo); */
                   12381:     /* } */
                   12382:     /* ungetc(c,ficpar); */
1.126     brouard  12383:     
                   12384:     estepm=0;
1.209     brouard  12385:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12386:       
                   12387:       if (num_filled != 6) {
                   12388:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12389:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12390:        goto end;
                   12391:       }
                   12392:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12393:     }
                   12394:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12395:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12396:     
1.209     brouard  12397:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12398:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12399:     if (fage <= 2) {
                   12400:       bage = ageminpar;
                   12401:       fage = agemaxpar;
                   12402:     }
                   12403:     
                   12404:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12405:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12406:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12407:                
1.186     brouard  12408:     /* Other stuffs, more or less useful */    
1.254     brouard  12409:     while(fgets(line, MAXLINE, ficpar)) {
                   12410:       /* If line starts with a # it is a comment */
                   12411:       if (line[0] == '#') {
                   12412:        numlinepar++;
                   12413:        fputs(line,stdout);
                   12414:        fputs(line,ficparo);
                   12415:        fputs(line,ficlog);
1.299     brouard  12416:        fputs(line,ficres);
1.254     brouard  12417:        continue;
                   12418:       }else
                   12419:        break;
                   12420:     }
                   12421: 
                   12422:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12423:       
                   12424:       if (num_filled != 7) {
                   12425:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12426:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12427:        goto end;
                   12428:       }
                   12429:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12430:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12431:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12432:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12433:     }
1.254     brouard  12434: 
                   12435:     while(fgets(line, MAXLINE, ficpar)) {
                   12436:       /* If line starts with a # it is a comment */
                   12437:       if (line[0] == '#') {
                   12438:        numlinepar++;
                   12439:        fputs(line,stdout);
                   12440:        fputs(line,ficparo);
                   12441:        fputs(line,ficlog);
1.299     brouard  12442:        fputs(line,ficres);
1.254     brouard  12443:        continue;
                   12444:       }else
                   12445:        break;
1.126     brouard  12446:     }
                   12447:     
                   12448:     
                   12449:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12450:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12451:     
1.254     brouard  12452:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12453:       if (num_filled != 1) {
                   12454:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12455:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12456:        goto end;
                   12457:       }
                   12458:       printf("pop_based=%d\n",popbased);
                   12459:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12460:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12461:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12462:     }
                   12463:      
1.258     brouard  12464:     /* Results */
1.307     brouard  12465:     endishere=0;
1.258     brouard  12466:     nresult=0;
1.308     brouard  12467:     parameterline=0;
1.258     brouard  12468:     do{
                   12469:       if(!fgets(line, MAXLINE, ficpar)){
                   12470:        endishere=1;
1.308     brouard  12471:        parameterline=15;
1.258     brouard  12472:       }else if (line[0] == '#') {
                   12473:        /* If line starts with a # it is a comment */
1.254     brouard  12474:        numlinepar++;
                   12475:        fputs(line,stdout);
                   12476:        fputs(line,ficparo);
                   12477:        fputs(line,ficlog);
1.299     brouard  12478:        fputs(line,ficres);
1.254     brouard  12479:        continue;
1.258     brouard  12480:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12481:        parameterline=11;
1.296     brouard  12482:       else if(sscanf(line,"prevbackcast=%[^\n]\n",modeltemp))
1.258     brouard  12483:        parameterline=12;
1.307     brouard  12484:       else if(sscanf(line,"result:%[^\n]\n",modeltemp)){
1.258     brouard  12485:        parameterline=13;
1.307     brouard  12486:       }
1.258     brouard  12487:       else{
                   12488:        parameterline=14;
1.254     brouard  12489:       }
1.308     brouard  12490:       switch (parameterline){ /* =0 only if only comments */
1.258     brouard  12491:       case 11:
1.296     brouard  12492:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12493:                  fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.258     brouard  12494:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12495:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12496:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12497:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12498:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12499:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
1.296     brouard  12500:           prvforecast = 1;
                   12501:        } 
                   12502:        else if((num_filled=sscanf(line,"prevforecast=%d yearsfproj=%lf mobil_average=%d\n",&prevfcast,&yrfproj,&mobilavproj)) !=EOF){/* && (num_filled == 3))*/
1.302     brouard  12503:          printf("prevforecast=%d yearsfproj=%lf.2 mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12504:          fprintf(ficlog,"prevforecast=%d yearsfproj=%lf.2 mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12505:          fprintf(ficres,"prevforecast=%d yearsfproj=%lf.2 mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
1.296     brouard  12506:           prvforecast = 2;
                   12507:        }
                   12508:        else {
                   12509:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearsfproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12510:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12511:          goto end;
1.258     brouard  12512:        }
1.254     brouard  12513:        break;
1.258     brouard  12514:       case 12:
1.296     brouard  12515:        if((num_filled=sscanf(line,"prevbackcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&prevbcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12516:           fprintf(ficparo,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12517:          printf("prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12518:          fprintf(ficlog,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12519:          fprintf(ficres,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12520:          /* day and month of back2 are not used but only year anback2.*/
1.273     brouard  12521:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12522:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.296     brouard  12523:           prvbackcast = 1;
                   12524:        } 
                   12525:        else if((num_filled=sscanf(line,"prevbackcast=%d yearsbproj=%lf mobil_average=%d\n",&prevbcast,&yrbproj,&mobilavproj)) ==3){/* && (num_filled == 3))*/
1.302     brouard  12526:          printf("prevbackcast=%d yearsbproj=%lf.2 mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12527:          fprintf(ficlog,"prevbackcast=%d yearsbproj=%lf.2 mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12528:          fprintf(ficres,"prevbackcast=%d yearsbproj=%lf.2 mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
1.296     brouard  12529:           prvbackcast = 2;
                   12530:        }
                   12531:        else {
                   12532:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearsbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12533:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12534:          goto end;
1.258     brouard  12535:        }
1.230     brouard  12536:        break;
1.258     brouard  12537:       case 13:
1.307     brouard  12538:        num_filled=sscanf(line,"result:%[^\n]\n",resultline);
                   12539:        nresult++; /* Sum of resultlines */
                   12540:        printf("Result %d: result:%s\n",nresult, resultline);
                   12541:        if(nresult > MAXRESULTLINES){
                   12542:          printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINES,nresult,rfileres);
                   12543:          fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINES,nresult,rfileres);
                   12544:          goto end;
                   12545:        }
1.310     brouard  12546:        if(!decoderesult(resultline, nresult)){ /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.307     brouard  12547:        fprintf(ficparo,"result: %s\n",resultline);
                   12548:        fprintf(ficres,"result: %s\n",resultline);
                   12549:        fprintf(ficlog,"result: %s\n",resultline);
1.310     brouard  12550:        } else
                   12551:          goto end;
1.307     brouard  12552:        break;
                   12553:       case 14:
                   12554:        printf("Error: Unknown command '%s'\n",line);
                   12555:        fprintf(ficlog,"Error: Unknown command '%s'\n",line);
                   12556:        if(ncovmodel >=2 && nresult==0 ){
                   12557:          printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
                   12558:          fprintf(ficlog,"ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12559:        }
1.307     brouard  12560:        /* goto end; */
                   12561:        break;
1.308     brouard  12562:       case 15:
                   12563:        printf("End of resultlines.\n");
                   12564:        fprintf(ficlog,"End of resultlines.\n");
                   12565:        break;
                   12566:       default: /* parameterline =0 */
1.307     brouard  12567:        nresult=1;
                   12568:        decoderesult(".",nresult ); /* No covariate */
1.258     brouard  12569:       } /* End switch parameterline */
                   12570:     }while(endishere==0); /* End do */
1.126     brouard  12571:     
1.230     brouard  12572:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12573:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12574:     
                   12575:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12576:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12577:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12578: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12579: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12580:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12581: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12582: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12583:     }else{
1.270     brouard  12584:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
1.296     brouard  12585:       /* It seems that anprojd which is computed from the mean year at interview which is known yet because of freqsummary */
                   12586:       /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */ /* Done in freqsummary */
                   12587:       if(prvforecast==1){
                   12588:         dateprojd=(jproj1+12*mproj1+365*anproj1)/365;
                   12589:         jprojd=jproj1;
                   12590:         mprojd=mproj1;
                   12591:         anprojd=anproj1;
                   12592:         dateprojf=(jproj2+12*mproj2+365*anproj2)/365;
                   12593:         jprojf=jproj2;
                   12594:         mprojf=mproj2;
                   12595:         anprojf=anproj2;
                   12596:       } else if(prvforecast == 2){
                   12597:         dateprojd=dateintmean;
                   12598:         date2dmy(dateprojd,&jprojd, &mprojd, &anprojd);
                   12599:         dateprojf=dateintmean+yrfproj;
                   12600:         date2dmy(dateprojf,&jprojf, &mprojf, &anprojf);
                   12601:       }
                   12602:       if(prvbackcast==1){
                   12603:         datebackd=(jback1+12*mback1+365*anback1)/365;
                   12604:         jbackd=jback1;
                   12605:         mbackd=mback1;
                   12606:         anbackd=anback1;
                   12607:         datebackf=(jback2+12*mback2+365*anback2)/365;
                   12608:         jbackf=jback2;
                   12609:         mbackf=mback2;
                   12610:         anbackf=anback2;
                   12611:       } else if(prvbackcast == 2){
                   12612:         datebackd=dateintmean;
                   12613:         date2dmy(datebackd,&jbackd, &mbackd, &anbackd);
                   12614:         datebackf=dateintmean-yrbproj;
                   12615:         date2dmy(datebackf,&jbackf, &mbackf, &anbackf);
                   12616:       }
                   12617:       
                   12618:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, prevbcast, pathc,p, (int)anprojd-bage, (int)anbackd-fage);
1.220     brouard  12619:     }
                   12620:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.296     brouard  12621:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,prevbcast, estepm, \
                   12622:                 jprev1,mprev1,anprev1,dateprev1, dateprojd, datebackd,jprev2,mprev2,anprev2,dateprev2,dateprojf, datebackf);
1.220     brouard  12623:                
1.225     brouard  12624:     /*------------ free_vector  -------------*/
                   12625:     /*  chdir(path); */
1.220     brouard  12626:                
1.215     brouard  12627:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12628:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12629:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12630:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12631:     free_lvector(num,firstobs,lastobs);
                   12632:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12633:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12634:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12635:     fclose(ficparo);
                   12636:     fclose(ficres);
1.220     brouard  12637:                
                   12638:                
1.186     brouard  12639:     /* Other results (useful)*/
1.220     brouard  12640:                
                   12641:                
1.126     brouard  12642:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12643:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12644:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12645:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12646:     fclose(ficrespl);
                   12647: 
                   12648:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12649:     /*#include "hpijx.h"*/
                   12650:     hPijx(p, bage, fage);
1.145     brouard  12651:     fclose(ficrespij);
1.227     brouard  12652:     
1.220     brouard  12653:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12654:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12655:     k=1;
1.126     brouard  12656:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12657:     
1.269     brouard  12658:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12659:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12660:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12661:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12662:        for(k=1;k<=ncovcombmax;k++)
                   12663:          probs[i][j][k]=0.;
1.269     brouard  12664:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12665:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12666:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12667:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12668:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12669:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12670:          for(k=1;k<=ncovcombmax;k++)
                   12671:            mobaverages[i][j][k]=0.;
1.219     brouard  12672:       mobaverage=mobaverages;
                   12673:       if (mobilav!=0) {
1.235     brouard  12674:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12675:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12676:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12677:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12678:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12679:        }
1.269     brouard  12680:       } else if (mobilavproj !=0) {
1.235     brouard  12681:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12682:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12683:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12684:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12685:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12686:        }
1.269     brouard  12687:       }else{
                   12688:        printf("Internal error moving average\n");
                   12689:        fflush(stdout);
                   12690:        exit(1);
1.219     brouard  12691:       }
                   12692:     }/* end if moving average */
1.227     brouard  12693:     
1.126     brouard  12694:     /*---------- Forecasting ------------------*/
1.296     brouard  12695:     if(prevfcast==1){ 
                   12696:       /*   /\*    if(stepm ==1){*\/ */
                   12697:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12698:       /*This done previously after freqsummary.*/
                   12699:       /*   dateprojd=(jproj1+12*mproj1+365*anproj1)/365; */
                   12700:       /*   dateprojf=(jproj2+12*mproj2+365*anproj2)/365; */
                   12701:       
                   12702:       /* } else if (prvforecast==2){ */
                   12703:       /*   /\*    if(stepm ==1){*\/ */
                   12704:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12705:       /* } */
                   12706:       /*prevforecast(fileresu, dateintmean, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);*/
                   12707:       prevforecast(fileresu,dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, p, cptcoveff);
1.126     brouard  12708:     }
1.269     brouard  12709: 
1.296     brouard  12710:     /* Prevbcasting */
                   12711:     if(prevbcast==1){
1.219     brouard  12712:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12713:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12714:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12715: 
                   12716:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12717: 
                   12718:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12719: 
1.219     brouard  12720:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12721:       fclose(ficresplb);
                   12722: 
1.222     brouard  12723:       hBijx(p, bage, fage, mobaverage);
                   12724:       fclose(ficrespijb);
1.219     brouard  12725: 
1.296     brouard  12726:       /* /\* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, *\/ */
                   12727:       /* /\*                  mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); *\/ */
                   12728:       /* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, */
                   12729:       /*                      mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
                   12730:       prevbackforecast(fileresu, mobaverage, dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2,
                   12731:                       mobilavproj, bage, fage, firstpass, lastpass, p, cptcoveff);
                   12732: 
                   12733:       
1.269     brouard  12734:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12735: 
                   12736:       
1.269     brouard  12737:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12738:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12739:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12740:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.296     brouard  12741:     }    /* end  Prevbcasting */
1.268     brouard  12742:  
1.186     brouard  12743:  
                   12744:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12745: 
1.215     brouard  12746:     free_ivector(wav,1,imx);
                   12747:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12748:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12749:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12750:                
                   12751:                
1.127     brouard  12752:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12753:                
1.201     brouard  12754:     strcpy(filerese,"E_");
                   12755:     strcat(filerese,fileresu);
1.126     brouard  12756:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12757:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12758:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12759:     }
1.208     brouard  12760:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12761:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12762: 
                   12763:     pstamp(ficreseij);
1.219     brouard  12764:                
1.235     brouard  12765:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12766:     if (cptcovn < 1){i1=1;}
                   12767:     
                   12768:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12769:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12770:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12771:        continue;
1.219     brouard  12772:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12773:       printf("\n#****** ");
1.225     brouard  12774:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12775:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12776:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12777:       }
                   12778:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12779:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12780:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12781:       }
                   12782:       fprintf(ficreseij,"******\n");
1.235     brouard  12783:       printf("******\n");
1.219     brouard  12784:       
                   12785:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12786:       oldm=oldms;savm=savms;
1.235     brouard  12787:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12788:       
1.219     brouard  12789:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12790:     }
                   12791:     fclose(ficreseij);
1.208     brouard  12792:     printf("done evsij\n");fflush(stdout);
                   12793:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12794: 
1.218     brouard  12795:                
1.227     brouard  12796:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12797:                
1.201     brouard  12798:     strcpy(filerest,"T_");
                   12799:     strcat(filerest,fileresu);
1.127     brouard  12800:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12801:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12802:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12803:     }
1.208     brouard  12804:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12805:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12806:     strcpy(fileresstde,"STDE_");
                   12807:     strcat(fileresstde,fileresu);
1.126     brouard  12808:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12809:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12810:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12811:     }
1.227     brouard  12812:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12813:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12814: 
1.201     brouard  12815:     strcpy(filerescve,"CVE_");
                   12816:     strcat(filerescve,fileresu);
1.126     brouard  12817:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12818:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12819:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12820:     }
1.227     brouard  12821:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12822:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12823: 
1.201     brouard  12824:     strcpy(fileresv,"V_");
                   12825:     strcat(fileresv,fileresu);
1.126     brouard  12826:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12827:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12828:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12829:     }
1.227     brouard  12830:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12831:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12832: 
1.235     brouard  12833:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12834:     if (cptcovn < 1){i1=1;}
                   12835:     
                   12836:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12837:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12838:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12839:        continue;
1.242     brouard  12840:       printf("\n#****** Result for:");
                   12841:       fprintf(ficrest,"\n#****** Result for:");
                   12842:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12843:       for(j=1;j<=cptcoveff;j++){ 
                   12844:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12845:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12846:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12847:       }
1.235     brouard  12848:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12849:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12850:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12851:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12852:       }        
1.208     brouard  12853:       fprintf(ficrest,"******\n");
1.227     brouard  12854:       fprintf(ficlog,"******\n");
                   12855:       printf("******\n");
1.208     brouard  12856:       
                   12857:       fprintf(ficresstdeij,"\n#****** ");
                   12858:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12859:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12860:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12861:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12862:       }
1.235     brouard  12863:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12864:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12865:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12866:       }        
1.208     brouard  12867:       fprintf(ficresstdeij,"******\n");
                   12868:       fprintf(ficrescveij,"******\n");
                   12869:       
                   12870:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12871:       /* pstamp(ficresvij); */
1.225     brouard  12872:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12873:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12874:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12875:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12876:       }        
1.208     brouard  12877:       fprintf(ficresvij,"******\n");
                   12878:       
                   12879:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12880:       oldm=oldms;savm=savms;
1.235     brouard  12881:       printf(" cvevsij ");
                   12882:       fprintf(ficlog, " cvevsij ");
                   12883:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12884:       printf(" end cvevsij \n ");
                   12885:       fprintf(ficlog, " end cvevsij \n ");
                   12886:       
                   12887:       /*
                   12888:        */
                   12889:       /* goto endfree; */
                   12890:       
                   12891:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12892:       pstamp(ficrest);
                   12893:       
1.269     brouard  12894:       epj=vector(1,nlstate+1);
1.208     brouard  12895:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12896:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12897:        cptcod= 0; /* To be deleted */
                   12898:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12899:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12900:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12901:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12902:        if(vpopbased==1)
                   12903:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12904:        else
1.288     brouard  12905:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12906:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12907:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12908:        fprintf(ficrest,"\n");
                   12909:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  12910:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   12911:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12912:        for(age=bage; age <=fage ;age++){
1.235     brouard  12913:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12914:          if (vpopbased==1) {
                   12915:            if(mobilav ==0){
                   12916:              for(i=1; i<=nlstate;i++)
                   12917:                prlim[i][i]=probs[(int)age][i][k];
                   12918:            }else{ /* mobilav */ 
                   12919:              for(i=1; i<=nlstate;i++)
                   12920:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12921:            }
                   12922:          }
1.219     brouard  12923:          
1.227     brouard  12924:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12925:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12926:          /* printf(" age %4.0f ",age); */
                   12927:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12928:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12929:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12930:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12931:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12932:            }
                   12933:            epj[nlstate+1] +=epj[j];
                   12934:          }
                   12935:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12936:          
1.227     brouard  12937:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12938:            for(j=1;j <=nlstate;j++)
                   12939:              vepp += vareij[i][j][(int)age];
                   12940:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12941:          for(j=1;j <=nlstate;j++){
                   12942:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12943:          }
                   12944:          fprintf(ficrest,"\n");
                   12945:        }
1.208     brouard  12946:       } /* End vpopbased */
1.269     brouard  12947:       free_vector(epj,1,nlstate+1);
1.208     brouard  12948:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12949:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12950:       printf("done selection\n");fflush(stdout);
                   12951:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12952:       
1.235     brouard  12953:     } /* End k selection */
1.227     brouard  12954: 
                   12955:     printf("done State-specific expectancies\n");fflush(stdout);
                   12956:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12957: 
1.288     brouard  12958:     /* variance-covariance of forward period prevalence*/
1.269     brouard  12959:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12960: 
1.227     brouard  12961:     
1.290     brouard  12962:     free_vector(weight,firstobs,lastobs);
1.227     brouard  12963:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  12964:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   12965:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   12966:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   12967:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  12968:     free_ivector(tab,1,NCOVMAX);
                   12969:     fclose(ficresstdeij);
                   12970:     fclose(ficrescveij);
                   12971:     fclose(ficresvij);
                   12972:     fclose(ficrest);
                   12973:     fclose(ficpar);
                   12974:     
                   12975:     
1.126     brouard  12976:     /*---------- End : free ----------------*/
1.219     brouard  12977:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  12978:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   12979:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  12980:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   12981:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  12982:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  12983:   /* endfree:*/
                   12984:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12985:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   12986:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  12987:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   12988:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   12989:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   12990:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  12991:   free_matrix(matcov,1,npar,1,npar);
                   12992:   free_matrix(hess,1,npar,1,npar);
                   12993:   /*free_vector(delti,1,npar);*/
                   12994:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   12995:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  12996:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  12997:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   12998:   
                   12999:   free_ivector(ncodemax,1,NCOVMAX);
                   13000:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   13001:   free_ivector(Dummy,-1,NCOVMAX);
                   13002:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  13003:   free_ivector(DummyV,1,NCOVMAX);
                   13004:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  13005:   free_ivector(Typevar,-1,NCOVMAX);
                   13006:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  13007:   free_ivector(TvarsQ,1,NCOVMAX);
                   13008:   free_ivector(TvarsQind,1,NCOVMAX);
                   13009:   free_ivector(TvarsD,1,NCOVMAX);
                   13010:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  13011:   free_ivector(TvarFD,1,NCOVMAX);
                   13012:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  13013:   free_ivector(TvarF,1,NCOVMAX);
                   13014:   free_ivector(TvarFind,1,NCOVMAX);
                   13015:   free_ivector(TvarV,1,NCOVMAX);
                   13016:   free_ivector(TvarVind,1,NCOVMAX);
                   13017:   free_ivector(TvarA,1,NCOVMAX);
                   13018:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  13019:   free_ivector(TvarFQ,1,NCOVMAX);
                   13020:   free_ivector(TvarFQind,1,NCOVMAX);
                   13021:   free_ivector(TvarVD,1,NCOVMAX);
                   13022:   free_ivector(TvarVDind,1,NCOVMAX);
                   13023:   free_ivector(TvarVQ,1,NCOVMAX);
                   13024:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  13025:   free_ivector(Tvarsel,1,NCOVMAX);
                   13026:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  13027:   free_ivector(Tposprod,1,NCOVMAX);
                   13028:   free_ivector(Tprod,1,NCOVMAX);
                   13029:   free_ivector(Tvaraff,1,NCOVMAX);
                   13030:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   13031:   free_ivector(Tage,1,NCOVMAX);
                   13032:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  13033:   free_ivector(TmodelInvind,1,NCOVMAX);
                   13034:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  13035:   
                   13036:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   13037:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  13038:   fflush(fichtm);
                   13039:   fflush(ficgp);
                   13040:   
1.227     brouard  13041:   
1.126     brouard  13042:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  13043:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   13044:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  13045:   }else{
                   13046:     printf("End of Imach\n");
                   13047:     fprintf(ficlog,"End of Imach\n");
                   13048:   }
                   13049:   printf("See log file on %s\n",filelog);
                   13050:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  13051:   /*(void) gettimeofday(&end_time,&tzp);*/
                   13052:   rend_time = time(NULL);  
                   13053:   end_time = *localtime(&rend_time);
                   13054:   /* tml = *localtime(&end_time.tm_sec); */
                   13055:   strcpy(strtend,asctime(&end_time));
1.126     brouard  13056:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   13057:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  13058:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  13059:   
1.157     brouard  13060:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   13061:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   13062:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  13063:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   13064: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   13065:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13066:   fclose(fichtm);
                   13067:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13068:   fclose(fichtmcov);
                   13069:   fclose(ficgp);
                   13070:   fclose(ficlog);
                   13071:   /*------ End -----------*/
1.227     brouard  13072:   
1.281     brouard  13073: 
                   13074: /* Executes gnuplot */
1.227     brouard  13075:   
                   13076:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  13077: #ifdef WIN32
1.227     brouard  13078:   if (_chdir(pathcd) != 0)
                   13079:     printf("Can't move to directory %s!\n",path);
                   13080:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  13081: #else
1.227     brouard  13082:     if(chdir(pathcd) != 0)
                   13083:       printf("Can't move to directory %s!\n", path);
                   13084:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  13085: #endif 
1.126     brouard  13086:     printf("Current directory %s!\n",pathcd);
                   13087:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   13088:   sprintf(plotcmd,"gnuplot");
1.157     brouard  13089: #ifdef _WIN32
1.126     brouard  13090:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   13091: #endif
                   13092:   if(!stat(plotcmd,&info)){
1.158     brouard  13093:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13094:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  13095:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  13096:     }else
                   13097:       strcpy(pplotcmd,plotcmd);
1.157     brouard  13098: #ifdef __unix
1.126     brouard  13099:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   13100:     if(!stat(plotcmd,&info)){
1.158     brouard  13101:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13102:     }else
                   13103:       strcpy(pplotcmd,plotcmd);
                   13104: #endif
                   13105:   }else
                   13106:     strcpy(pplotcmd,plotcmd);
                   13107:   
                   13108:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  13109:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292     brouard  13110:   strcpy(pplotcmd,plotcmd);
1.227     brouard  13111:   
1.126     brouard  13112:   if((outcmd=system(plotcmd)) != 0){
1.292     brouard  13113:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  13114:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  13115:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292     brouard  13116:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  13117:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292     brouard  13118:       strcpy(plotcmd,pplotcmd);
                   13119:     }
1.126     brouard  13120:   }
1.158     brouard  13121:   printf(" Successful, please wait...");
1.126     brouard  13122:   while (z[0] != 'q') {
                   13123:     /* chdir(path); */
1.154     brouard  13124:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  13125:     scanf("%s",z);
                   13126: /*     if (z[0] == 'c') system("./imach"); */
                   13127:     if (z[0] == 'e') {
1.158     brouard  13128: #ifdef __APPLE__
1.152     brouard  13129:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  13130: #elif __linux
                   13131:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  13132: #else
1.152     brouard  13133:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  13134: #endif
                   13135:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   13136:       system(pplotcmd);
1.126     brouard  13137:     }
                   13138:     else if (z[0] == 'g') system(plotcmd);
                   13139:     else if (z[0] == 'q') exit(0);
                   13140:   }
1.227     brouard  13141: end:
1.126     brouard  13142:   while (z[0] != 'q') {
1.195     brouard  13143:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  13144:     scanf("%s",z);
                   13145:   }
1.283     brouard  13146:   printf("End\n");
1.282     brouard  13147:   exit(0);
1.126     brouard  13148: }

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