Annotation of imach/src/imach.c, revision 1.315

1.315   ! brouard     1: /* $Id: imach.c,v 1.314 2022/04/13 17:43:09 brouard Exp $
1.126     brouard     2:   $State: Exp $
1.163     brouard     3:   $Log: imach.c,v $
1.315   ! brouard     4:   Revision 1.314  2022/04/13 17:43:09  brouard
        !             5:   * imach.c (Module): Adding link to text data files
        !             6: 
1.314     brouard     7:   Revision 1.313  2022/04/11 15:57:42  brouard
                      8:   * imach.c (Module): Error in rewriting the 'r' file with yearsfproj or yearsbproj fixed
                      9: 
1.313     brouard    10:   Revision 1.312  2022/04/05 21:24:39  brouard
                     11:   *** empty log message ***
                     12: 
1.312     brouard    13:   Revision 1.311  2022/04/05 21:03:51  brouard
                     14:   Summary: Fixed quantitative covariates
                     15: 
                     16:          Fixed covariates (dummy or quantitative)
                     17:        with missing values have never been allowed but are ERRORS and
                     18:        program quits. Standard deviations of fixed covariates were
                     19:        wrongly computed. Mean and standard deviations of time varying
                     20:        covariates are still not computed.
                     21: 
1.311     brouard    22:   Revision 1.310  2022/03/17 08:45:53  brouard
                     23:   Summary: 99r25
                     24: 
                     25:   Improving detection of errors: result lines should be compatible with
                     26:   the model.
                     27: 
1.310     brouard    28:   Revision 1.309  2021/05/20 12:39:14  brouard
                     29:   Summary: Version 0.99r24
                     30: 
1.309     brouard    31:   Revision 1.308  2021/03/31 13:11:57  brouard
                     32:   Summary: Version 0.99r23
                     33: 
                     34: 
                     35:   * imach.c (Module): Still bugs in the result loop. Thank to Holly Benett
                     36: 
1.308     brouard    37:   Revision 1.307  2021/03/08 18:11:32  brouard
                     38:   Summary: 0.99r22 fixed bug on result:
                     39: 
1.307     brouard    40:   Revision 1.306  2021/02/20 15:44:02  brouard
                     41:   Summary: Version 0.99r21
                     42: 
                     43:   * imach.c (Module): Fix bug on quitting after result lines!
                     44:   (Module): Version 0.99r21
                     45: 
1.306     brouard    46:   Revision 1.305  2021/02/20 15:28:30  brouard
                     47:   * imach.c (Module): Fix bug on quitting after result lines!
                     48: 
1.305     brouard    49:   Revision 1.304  2021/02/12 11:34:20  brouard
                     50:   * imach.c (Module): The use of a Windows BOM (huge) file is now an error
                     51: 
1.304     brouard    52:   Revision 1.303  2021/02/11 19:50:15  brouard
                     53:   *  (Module): imach.c Someone entered 'results:' instead of 'result:'. Now it is an error which is printed.
                     54: 
1.303     brouard    55:   Revision 1.302  2020/02/22 21:00:05  brouard
                     56:   *  (Module): imach.c Update mle=-3 (for computing Life expectancy
                     57:   and life table from the data without any state)
                     58: 
1.302     brouard    59:   Revision 1.301  2019/06/04 13:51:20  brouard
                     60:   Summary: Error in 'r'parameter file backcast yearsbproj instead of yearsfproj
                     61: 
1.301     brouard    62:   Revision 1.300  2019/05/22 19:09:45  brouard
                     63:   Summary: version 0.99r19 of May 2019
                     64: 
1.300     brouard    65:   Revision 1.299  2019/05/22 18:37:08  brouard
                     66:   Summary: Cleaned 0.99r19
                     67: 
1.299     brouard    68:   Revision 1.298  2019/05/22 18:19:56  brouard
                     69:   *** empty log message ***
                     70: 
1.298     brouard    71:   Revision 1.297  2019/05/22 17:56:10  brouard
                     72:   Summary: Fix bug by moving date2dmy and nhstepm which gaefin=-1
                     73: 
1.297     brouard    74:   Revision 1.296  2019/05/20 13:03:18  brouard
                     75:   Summary: Projection syntax simplified
                     76: 
                     77: 
                     78:   We can now start projections, forward or backward, from the mean date
                     79:   of inteviews up to or down to a number of years of projection:
                     80:   prevforecast=1 yearsfproj=15.3 mobil_average=0
                     81:   or
                     82:   prevforecast=1 starting-proj-date=1/1/2007 final-proj-date=12/31/2017 mobil_average=0
                     83:   or
                     84:   prevbackcast=1 yearsbproj=12.3 mobil_average=1
                     85:   or
                     86:   prevbackcast=1 starting-back-date=1/10/1999 final-back-date=1/1/1985 mobil_average=1
                     87: 
1.296     brouard    88:   Revision 1.295  2019/05/18 09:52:50  brouard
                     89:   Summary: doxygen tex bug
                     90: 
1.295     brouard    91:   Revision 1.294  2019/05/16 14:54:33  brouard
                     92:   Summary: There was some wrong lines added
                     93: 
1.294     brouard    94:   Revision 1.293  2019/05/09 15:17:34  brouard
                     95:   *** empty log message ***
                     96: 
1.293     brouard    97:   Revision 1.292  2019/05/09 14:17:20  brouard
                     98:   Summary: Some updates
                     99: 
1.292     brouard   100:   Revision 1.291  2019/05/09 13:44:18  brouard
                    101:   Summary: Before ncovmax
                    102: 
1.291     brouard   103:   Revision 1.290  2019/05/09 13:39:37  brouard
                    104:   Summary: 0.99r18 unlimited number of individuals
                    105: 
                    106:   The number n which was limited to 20,000 cases is now unlimited, from firstobs to lastobs. If the number is too for the virtual memory, probably an error will occur.
                    107: 
1.290     brouard   108:   Revision 1.289  2018/12/13 09:16:26  brouard
                    109:   Summary: Bug for young ages (<-30) will be in r17
                    110: 
1.289     brouard   111:   Revision 1.288  2018/05/02 20:58:27  brouard
                    112:   Summary: Some bugs fixed
                    113: 
1.288     brouard   114:   Revision 1.287  2018/05/01 17:57:25  brouard
                    115:   Summary: Bug fixed by providing frequencies only for non missing covariates
                    116: 
1.287     brouard   117:   Revision 1.286  2018/04/27 14:27:04  brouard
                    118:   Summary: some minor bugs
                    119: 
1.286     brouard   120:   Revision 1.285  2018/04/21 21:02:16  brouard
                    121:   Summary: Some bugs fixed, valgrind tested
                    122: 
1.285     brouard   123:   Revision 1.284  2018/04/20 05:22:13  brouard
                    124:   Summary: Computing mean and stdeviation of fixed quantitative variables
                    125: 
1.284     brouard   126:   Revision 1.283  2018/04/19 14:49:16  brouard
                    127:   Summary: Some minor bugs fixed
                    128: 
1.283     brouard   129:   Revision 1.282  2018/02/27 22:50:02  brouard
                    130:   *** empty log message ***
                    131: 
1.282     brouard   132:   Revision 1.281  2018/02/27 19:25:23  brouard
                    133:   Summary: Adding second argument for quitting
                    134: 
1.281     brouard   135:   Revision 1.280  2018/02/21 07:58:13  brouard
                    136:   Summary: 0.99r15
                    137: 
                    138:   New Makefile with recent VirtualBox 5.26. Bug in sqrt negatve in imach.c
                    139: 
1.280     brouard   140:   Revision 1.279  2017/07/20 13:35:01  brouard
                    141:   Summary: temporary working
                    142: 
1.279     brouard   143:   Revision 1.278  2017/07/19 14:09:02  brouard
                    144:   Summary: Bug for mobil_average=0 and prevforecast fixed(?)
                    145: 
1.278     brouard   146:   Revision 1.277  2017/07/17 08:53:49  brouard
                    147:   Summary: BOM files can be read now
                    148: 
1.277     brouard   149:   Revision 1.276  2017/06/30 15:48:31  brouard
                    150:   Summary: Graphs improvements
                    151: 
1.276     brouard   152:   Revision 1.275  2017/06/30 13:39:33  brouard
                    153:   Summary: Saito's color
                    154: 
1.275     brouard   155:   Revision 1.274  2017/06/29 09:47:08  brouard
                    156:   Summary: Version 0.99r14
                    157: 
1.274     brouard   158:   Revision 1.273  2017/06/27 11:06:02  brouard
                    159:   Summary: More documentation on projections
                    160: 
1.273     brouard   161:   Revision 1.272  2017/06/27 10:22:40  brouard
                    162:   Summary: Color of backprojection changed from 6 to 5(yellow)
                    163: 
1.272     brouard   164:   Revision 1.271  2017/06/27 10:17:50  brouard
                    165:   Summary: Some bug with rint
                    166: 
1.271     brouard   167:   Revision 1.270  2017/05/24 05:45:29  brouard
                    168:   *** empty log message ***
                    169: 
1.270     brouard   170:   Revision 1.269  2017/05/23 08:39:25  brouard
                    171:   Summary: Code into subroutine, cleanings
                    172: 
1.269     brouard   173:   Revision 1.268  2017/05/18 20:09:32  brouard
                    174:   Summary: backprojection and confidence intervals of backprevalence
                    175: 
1.268     brouard   176:   Revision 1.267  2017/05/13 10:25:05  brouard
                    177:   Summary: temporary save for backprojection
                    178: 
1.267     brouard   179:   Revision 1.266  2017/05/13 07:26:12  brouard
                    180:   Summary: Version 0.99r13 (improvements and bugs fixed)
                    181: 
1.266     brouard   182:   Revision 1.265  2017/04/26 16:22:11  brouard
                    183:   Summary: imach 0.99r13 Some bugs fixed
                    184: 
1.265     brouard   185:   Revision 1.264  2017/04/26 06:01:29  brouard
                    186:   Summary: Labels in graphs
                    187: 
1.264     brouard   188:   Revision 1.263  2017/04/24 15:23:15  brouard
                    189:   Summary: to save
                    190: 
1.263     brouard   191:   Revision 1.262  2017/04/18 16:48:12  brouard
                    192:   *** empty log message ***
                    193: 
1.262     brouard   194:   Revision 1.261  2017/04/05 10:14:09  brouard
                    195:   Summary: Bug in E_ as well as in T_ fixed nres-1 vs k1-1
                    196: 
1.261     brouard   197:   Revision 1.260  2017/04/04 17:46:59  brouard
                    198:   Summary: Gnuplot indexations fixed (humm)
                    199: 
1.260     brouard   200:   Revision 1.259  2017/04/04 13:01:16  brouard
                    201:   Summary: Some errors to warnings only if date of death is unknown but status is death we could set to pi3
                    202: 
1.259     brouard   203:   Revision 1.258  2017/04/03 10:17:47  brouard
                    204:   Summary: Version 0.99r12
                    205: 
                    206:   Some cleanings, conformed with updated documentation.
                    207: 
1.258     brouard   208:   Revision 1.257  2017/03/29 16:53:30  brouard
                    209:   Summary: Temp
                    210: 
1.257     brouard   211:   Revision 1.256  2017/03/27 05:50:23  brouard
                    212:   Summary: Temporary
                    213: 
1.256     brouard   214:   Revision 1.255  2017/03/08 16:02:28  brouard
                    215:   Summary: IMaCh version 0.99r10 bugs in gnuplot fixed
                    216: 
1.255     brouard   217:   Revision 1.254  2017/03/08 07:13:00  brouard
                    218:   Summary: Fixing data parameter line
                    219: 
1.254     brouard   220:   Revision 1.253  2016/12/15 11:59:41  brouard
                    221:   Summary: 0.99 in progress
                    222: 
1.253     brouard   223:   Revision 1.252  2016/09/15 21:15:37  brouard
                    224:   *** empty log message ***
                    225: 
1.252     brouard   226:   Revision 1.251  2016/09/15 15:01:13  brouard
                    227:   Summary: not working
                    228: 
1.251     brouard   229:   Revision 1.250  2016/09/08 16:07:27  brouard
                    230:   Summary: continue
                    231: 
1.250     brouard   232:   Revision 1.249  2016/09/07 17:14:18  brouard
                    233:   Summary: Starting values from frequencies
                    234: 
1.249     brouard   235:   Revision 1.248  2016/09/07 14:10:18  brouard
                    236:   *** empty log message ***
                    237: 
1.248     brouard   238:   Revision 1.247  2016/09/02 11:11:21  brouard
                    239:   *** empty log message ***
                    240: 
1.247     brouard   241:   Revision 1.246  2016/09/02 08:49:22  brouard
                    242:   *** empty log message ***
                    243: 
1.246     brouard   244:   Revision 1.245  2016/09/02 07:25:01  brouard
                    245:   *** empty log message ***
                    246: 
1.245     brouard   247:   Revision 1.244  2016/09/02 07:17:34  brouard
                    248:   *** empty log message ***
                    249: 
1.244     brouard   250:   Revision 1.243  2016/09/02 06:45:35  brouard
                    251:   *** empty log message ***
                    252: 
1.243     brouard   253:   Revision 1.242  2016/08/30 15:01:20  brouard
                    254:   Summary: Fixing a lots
                    255: 
1.242     brouard   256:   Revision 1.241  2016/08/29 17:17:25  brouard
                    257:   Summary: gnuplot problem in Back projection to fix
                    258: 
1.241     brouard   259:   Revision 1.240  2016/08/29 07:53:18  brouard
                    260:   Summary: Better
                    261: 
1.240     brouard   262:   Revision 1.239  2016/08/26 15:51:03  brouard
                    263:   Summary: Improvement in Powell output in order to copy and paste
                    264: 
                    265:   Author:
                    266: 
1.239     brouard   267:   Revision 1.238  2016/08/26 14:23:35  brouard
                    268:   Summary: Starting tests of 0.99
                    269: 
1.238     brouard   270:   Revision 1.237  2016/08/26 09:20:19  brouard
                    271:   Summary: to valgrind
                    272: 
1.237     brouard   273:   Revision 1.236  2016/08/25 10:50:18  brouard
                    274:   *** empty log message ***
                    275: 
1.236     brouard   276:   Revision 1.235  2016/08/25 06:59:23  brouard
                    277:   *** empty log message ***
                    278: 
1.235     brouard   279:   Revision 1.234  2016/08/23 16:51:20  brouard
                    280:   *** empty log message ***
                    281: 
1.234     brouard   282:   Revision 1.233  2016/08/23 07:40:50  brouard
                    283:   Summary: not working
                    284: 
1.233     brouard   285:   Revision 1.232  2016/08/22 14:20:21  brouard
                    286:   Summary: not working
                    287: 
1.232     brouard   288:   Revision 1.231  2016/08/22 07:17:15  brouard
                    289:   Summary: not working
                    290: 
1.231     brouard   291:   Revision 1.230  2016/08/22 06:55:53  brouard
                    292:   Summary: Not working
                    293: 
1.230     brouard   294:   Revision 1.229  2016/07/23 09:45:53  brouard
                    295:   Summary: Completing for func too
                    296: 
1.229     brouard   297:   Revision 1.228  2016/07/22 17:45:30  brouard
                    298:   Summary: Fixing some arrays, still debugging
                    299: 
1.227     brouard   300:   Revision 1.226  2016/07/12 18:42:34  brouard
                    301:   Summary: temp
                    302: 
1.226     brouard   303:   Revision 1.225  2016/07/12 08:40:03  brouard
                    304:   Summary: saving but not running
                    305: 
1.225     brouard   306:   Revision 1.224  2016/07/01 13:16:01  brouard
                    307:   Summary: Fixes
                    308: 
1.224     brouard   309:   Revision 1.223  2016/02/19 09:23:35  brouard
                    310:   Summary: temporary
                    311: 
1.223     brouard   312:   Revision 1.222  2016/02/17 08:14:50  brouard
                    313:   Summary: Probably last 0.98 stable version 0.98r6
                    314: 
1.222     brouard   315:   Revision 1.221  2016/02/15 23:35:36  brouard
                    316:   Summary: minor bug
                    317: 
1.220     brouard   318:   Revision 1.219  2016/02/15 00:48:12  brouard
                    319:   *** empty log message ***
                    320: 
1.219     brouard   321:   Revision 1.218  2016/02/12 11:29:23  brouard
                    322:   Summary: 0.99 Back projections
                    323: 
1.218     brouard   324:   Revision 1.217  2015/12/23 17:18:31  brouard
                    325:   Summary: Experimental backcast
                    326: 
1.217     brouard   327:   Revision 1.216  2015/12/18 17:32:11  brouard
                    328:   Summary: 0.98r4 Warning and status=-2
                    329: 
                    330:   Version 0.98r4 is now:
                    331:    - displaying an error when status is -1, date of interview unknown and date of death known;
                    332:    - permitting a status -2 when the vital status is unknown at a known date of right truncation.
                    333:   Older changes concerning s=-2, dating from 2005 have been supersed.
                    334: 
1.216     brouard   335:   Revision 1.215  2015/12/16 08:52:24  brouard
                    336:   Summary: 0.98r4 working
                    337: 
1.215     brouard   338:   Revision 1.214  2015/12/16 06:57:54  brouard
                    339:   Summary: temporary not working
                    340: 
1.214     brouard   341:   Revision 1.213  2015/12/11 18:22:17  brouard
                    342:   Summary: 0.98r4
                    343: 
1.213     brouard   344:   Revision 1.212  2015/11/21 12:47:24  brouard
                    345:   Summary: minor typo
                    346: 
1.212     brouard   347:   Revision 1.211  2015/11/21 12:41:11  brouard
                    348:   Summary: 0.98r3 with some graph of projected cross-sectional
                    349: 
                    350:   Author: Nicolas Brouard
                    351: 
1.211     brouard   352:   Revision 1.210  2015/11/18 17:41:20  brouard
1.252     brouard   353:   Summary: Start working on projected prevalences  Revision 1.209  2015/11/17 22:12:03  brouard
1.210     brouard   354:   Summary: Adding ftolpl parameter
                    355:   Author: N Brouard
                    356: 
                    357:   We had difficulties to get smoothed confidence intervals. It was due
                    358:   to the period prevalence which wasn't computed accurately. The inner
                    359:   parameter ftolpl is now an outer parameter of the .imach parameter
                    360:   file after estepm. If ftolpl is small 1.e-4 and estepm too,
                    361:   computation are long.
                    362: 
1.209     brouard   363:   Revision 1.208  2015/11/17 14:31:57  brouard
                    364:   Summary: temporary
                    365: 
1.208     brouard   366:   Revision 1.207  2015/10/27 17:36:57  brouard
                    367:   *** empty log message ***
                    368: 
1.207     brouard   369:   Revision 1.206  2015/10/24 07:14:11  brouard
                    370:   *** empty log message ***
                    371: 
1.206     brouard   372:   Revision 1.205  2015/10/23 15:50:53  brouard
                    373:   Summary: 0.98r3 some clarification for graphs on likelihood contributions
                    374: 
1.205     brouard   375:   Revision 1.204  2015/10/01 16:20:26  brouard
                    376:   Summary: Some new graphs of contribution to likelihood
                    377: 
1.204     brouard   378:   Revision 1.203  2015/09/30 17:45:14  brouard
                    379:   Summary: looking at better estimation of the hessian
                    380: 
                    381:   Also a better criteria for convergence to the period prevalence And
                    382:   therefore adding the number of years needed to converge. (The
                    383:   prevalence in any alive state shold sum to one
                    384: 
1.203     brouard   385:   Revision 1.202  2015/09/22 19:45:16  brouard
                    386:   Summary: Adding some overall graph on contribution to likelihood. Might change
                    387: 
1.202     brouard   388:   Revision 1.201  2015/09/15 17:34:58  brouard
                    389:   Summary: 0.98r0
                    390: 
                    391:   - Some new graphs like suvival functions
                    392:   - Some bugs fixed like model=1+age+V2.
                    393: 
1.201     brouard   394:   Revision 1.200  2015/09/09 16:53:55  brouard
                    395:   Summary: Big bug thanks to Flavia
                    396: 
                    397:   Even model=1+age+V2. did not work anymore
                    398: 
1.200     brouard   399:   Revision 1.199  2015/09/07 14:09:23  brouard
                    400:   Summary: 0.98q6 changing default small png format for graph to vectorized svg.
                    401: 
1.199     brouard   402:   Revision 1.198  2015/09/03 07:14:39  brouard
                    403:   Summary: 0.98q5 Flavia
                    404: 
1.198     brouard   405:   Revision 1.197  2015/09/01 18:24:39  brouard
                    406:   *** empty log message ***
                    407: 
1.197     brouard   408:   Revision 1.196  2015/08/18 23:17:52  brouard
                    409:   Summary: 0.98q5
                    410: 
1.196     brouard   411:   Revision 1.195  2015/08/18 16:28:39  brouard
                    412:   Summary: Adding a hack for testing purpose
                    413: 
                    414:   After reading the title, ftol and model lines, if the comment line has
                    415:   a q, starting with #q, the answer at the end of the run is quit. It
                    416:   permits to run test files in batch with ctest. The former workaround was
                    417:   $ echo q | imach foo.imach
                    418: 
1.195     brouard   419:   Revision 1.194  2015/08/18 13:32:00  brouard
                    420:   Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
                    421: 
1.194     brouard   422:   Revision 1.193  2015/08/04 07:17:42  brouard
                    423:   Summary: 0.98q4
                    424: 
1.193     brouard   425:   Revision 1.192  2015/07/16 16:49:02  brouard
                    426:   Summary: Fixing some outputs
                    427: 
1.192     brouard   428:   Revision 1.191  2015/07/14 10:00:33  brouard
                    429:   Summary: Some fixes
                    430: 
1.191     brouard   431:   Revision 1.190  2015/05/05 08:51:13  brouard
                    432:   Summary: Adding digits in output parameters (7 digits instead of 6)
                    433: 
                    434:   Fix 1+age+.
                    435: 
1.190     brouard   436:   Revision 1.189  2015/04/30 14:45:16  brouard
                    437:   Summary: 0.98q2
                    438: 
1.189     brouard   439:   Revision 1.188  2015/04/30 08:27:53  brouard
                    440:   *** empty log message ***
                    441: 
1.188     brouard   442:   Revision 1.187  2015/04/29 09:11:15  brouard
                    443:   *** empty log message ***
                    444: 
1.187     brouard   445:   Revision 1.186  2015/04/23 12:01:52  brouard
                    446:   Summary: V1*age is working now, version 0.98q1
                    447: 
                    448:   Some codes had been disabled in order to simplify and Vn*age was
                    449:   working in the optimization phase, ie, giving correct MLE parameters,
                    450:   but, as usual, outputs were not correct and program core dumped.
                    451: 
1.186     brouard   452:   Revision 1.185  2015/03/11 13:26:42  brouard
                    453:   Summary: Inclusion of compile and links command line for Intel Compiler
                    454: 
1.185     brouard   455:   Revision 1.184  2015/03/11 11:52:39  brouard
                    456:   Summary: Back from Windows 8. Intel Compiler
                    457: 
1.184     brouard   458:   Revision 1.183  2015/03/10 20:34:32  brouard
                    459:   Summary: 0.98q0, trying with directest, mnbrak fixed
                    460: 
                    461:   We use directest instead of original Powell test; probably no
                    462:   incidence on the results, but better justifications;
                    463:   We fixed Numerical Recipes mnbrak routine which was wrong and gave
                    464:   wrong results.
                    465: 
1.183     brouard   466:   Revision 1.182  2015/02/12 08:19:57  brouard
                    467:   Summary: Trying to keep directest which seems simpler and more general
                    468:   Author: Nicolas Brouard
                    469: 
1.182     brouard   470:   Revision 1.181  2015/02/11 23:22:24  brouard
                    471:   Summary: Comments on Powell added
                    472: 
                    473:   Author:
                    474: 
1.181     brouard   475:   Revision 1.180  2015/02/11 17:33:45  brouard
                    476:   Summary: Finishing move from main to function (hpijx and prevalence_limit)
                    477: 
1.180     brouard   478:   Revision 1.179  2015/01/04 09:57:06  brouard
                    479:   Summary: back to OS/X
                    480: 
1.179     brouard   481:   Revision 1.178  2015/01/04 09:35:48  brouard
                    482:   *** empty log message ***
                    483: 
1.178     brouard   484:   Revision 1.177  2015/01/03 18:40:56  brouard
                    485:   Summary: Still testing ilc32 on OSX
                    486: 
1.177     brouard   487:   Revision 1.176  2015/01/03 16:45:04  brouard
                    488:   *** empty log message ***
                    489: 
1.176     brouard   490:   Revision 1.175  2015/01/03 16:33:42  brouard
                    491:   *** empty log message ***
                    492: 
1.175     brouard   493:   Revision 1.174  2015/01/03 16:15:49  brouard
                    494:   Summary: Still in cross-compilation
                    495: 
1.174     brouard   496:   Revision 1.173  2015/01/03 12:06:26  brouard
                    497:   Summary: trying to detect cross-compilation
                    498: 
1.173     brouard   499:   Revision 1.172  2014/12/27 12:07:47  brouard
                    500:   Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
                    501: 
1.172     brouard   502:   Revision 1.171  2014/12/23 13:26:59  brouard
                    503:   Summary: Back from Visual C
                    504: 
                    505:   Still problem with utsname.h on Windows
                    506: 
1.171     brouard   507:   Revision 1.170  2014/12/23 11:17:12  brouard
                    508:   Summary: Cleaning some \%% back to %%
                    509: 
                    510:   The escape was mandatory for a specific compiler (which one?), but too many warnings.
                    511: 
1.170     brouard   512:   Revision 1.169  2014/12/22 23:08:31  brouard
                    513:   Summary: 0.98p
                    514: 
                    515:   Outputs some informations on compiler used, OS etc. Testing on different platforms.
                    516: 
1.169     brouard   517:   Revision 1.168  2014/12/22 15:17:42  brouard
1.170     brouard   518:   Summary: update
1.169     brouard   519: 
1.168     brouard   520:   Revision 1.167  2014/12/22 13:50:56  brouard
                    521:   Summary: Testing uname and compiler version and if compiled 32 or 64
                    522: 
                    523:   Testing on Linux 64
                    524: 
1.167     brouard   525:   Revision 1.166  2014/12/22 11:40:47  brouard
                    526:   *** empty log message ***
                    527: 
1.166     brouard   528:   Revision 1.165  2014/12/16 11:20:36  brouard
                    529:   Summary: After compiling on Visual C
                    530: 
                    531:   * imach.c (Module): Merging 1.61 to 1.162
                    532: 
1.165     brouard   533:   Revision 1.164  2014/12/16 10:52:11  brouard
                    534:   Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
                    535: 
                    536:   * imach.c (Module): Merging 1.61 to 1.162
                    537: 
1.164     brouard   538:   Revision 1.163  2014/12/16 10:30:11  brouard
                    539:   * imach.c (Module): Merging 1.61 to 1.162
                    540: 
1.163     brouard   541:   Revision 1.162  2014/09/25 11:43:39  brouard
                    542:   Summary: temporary backup 0.99!
                    543: 
1.162     brouard   544:   Revision 1.1  2014/09/16 11:06:58  brouard
                    545:   Summary: With some code (wrong) for nlopt
                    546: 
                    547:   Author:
                    548: 
                    549:   Revision 1.161  2014/09/15 20:41:41  brouard
                    550:   Summary: Problem with macro SQR on Intel compiler
                    551: 
1.161     brouard   552:   Revision 1.160  2014/09/02 09:24:05  brouard
                    553:   *** empty log message ***
                    554: 
1.160     brouard   555:   Revision 1.159  2014/09/01 10:34:10  brouard
                    556:   Summary: WIN32
                    557:   Author: Brouard
                    558: 
1.159     brouard   559:   Revision 1.158  2014/08/27 17:11:51  brouard
                    560:   *** empty log message ***
                    561: 
1.158     brouard   562:   Revision 1.157  2014/08/27 16:26:55  brouard
                    563:   Summary: Preparing windows Visual studio version
                    564:   Author: Brouard
                    565: 
                    566:   In order to compile on Visual studio, time.h is now correct and time_t
                    567:   and tm struct should be used. difftime should be used but sometimes I
                    568:   just make the differences in raw time format (time(&now).
                    569:   Trying to suppress #ifdef LINUX
                    570:   Add xdg-open for __linux in order to open default browser.
                    571: 
1.157     brouard   572:   Revision 1.156  2014/08/25 20:10:10  brouard
                    573:   *** empty log message ***
                    574: 
1.156     brouard   575:   Revision 1.155  2014/08/25 18:32:34  brouard
                    576:   Summary: New compile, minor changes
                    577:   Author: Brouard
                    578: 
1.155     brouard   579:   Revision 1.154  2014/06/20 17:32:08  brouard
                    580:   Summary: Outputs now all graphs of convergence to period prevalence
                    581: 
1.154     brouard   582:   Revision 1.153  2014/06/20 16:45:46  brouard
                    583:   Summary: If 3 live state, convergence to period prevalence on same graph
                    584:   Author: Brouard
                    585: 
1.153     brouard   586:   Revision 1.152  2014/06/18 17:54:09  brouard
                    587:   Summary: open browser, use gnuplot on same dir than imach if not found in the path
                    588: 
1.152     brouard   589:   Revision 1.151  2014/06/18 16:43:30  brouard
                    590:   *** empty log message ***
                    591: 
1.151     brouard   592:   Revision 1.150  2014/06/18 16:42:35  brouard
                    593:   Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
                    594:   Author: brouard
                    595: 
1.150     brouard   596:   Revision 1.149  2014/06/18 15:51:14  brouard
                    597:   Summary: Some fixes in parameter files errors
                    598:   Author: Nicolas Brouard
                    599: 
1.149     brouard   600:   Revision 1.148  2014/06/17 17:38:48  brouard
                    601:   Summary: Nothing new
                    602:   Author: Brouard
                    603: 
                    604:   Just a new packaging for OS/X version 0.98nS
                    605: 
1.148     brouard   606:   Revision 1.147  2014/06/16 10:33:11  brouard
                    607:   *** empty log message ***
                    608: 
1.147     brouard   609:   Revision 1.146  2014/06/16 10:20:28  brouard
                    610:   Summary: Merge
                    611:   Author: Brouard
                    612: 
                    613:   Merge, before building revised version.
                    614: 
1.146     brouard   615:   Revision 1.145  2014/06/10 21:23:15  brouard
                    616:   Summary: Debugging with valgrind
                    617:   Author: Nicolas Brouard
                    618: 
                    619:   Lot of changes in order to output the results with some covariates
                    620:   After the Edimburgh REVES conference 2014, it seems mandatory to
                    621:   improve the code.
                    622:   No more memory valgrind error but a lot has to be done in order to
                    623:   continue the work of splitting the code into subroutines.
                    624:   Also, decodemodel has been improved. Tricode is still not
                    625:   optimal. nbcode should be improved. Documentation has been added in
                    626:   the source code.
                    627: 
1.144     brouard   628:   Revision 1.143  2014/01/26 09:45:38  brouard
                    629:   Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
                    630: 
                    631:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    632:   (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
                    633: 
1.143     brouard   634:   Revision 1.142  2014/01/26 03:57:36  brouard
                    635:   Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
                    636: 
                    637:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    638: 
1.142     brouard   639:   Revision 1.141  2014/01/26 02:42:01  brouard
                    640:   * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
                    641: 
1.141     brouard   642:   Revision 1.140  2011/09/02 10:37:54  brouard
                    643:   Summary: times.h is ok with mingw32 now.
                    644: 
1.140     brouard   645:   Revision 1.139  2010/06/14 07:50:17  brouard
                    646:   After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
                    647:   I remember having already fixed agemin agemax which are pointers now but not cvs saved.
                    648: 
1.139     brouard   649:   Revision 1.138  2010/04/30 18:19:40  brouard
                    650:   *** empty log message ***
                    651: 
1.138     brouard   652:   Revision 1.137  2010/04/29 18:11:38  brouard
                    653:   (Module): Checking covariates for more complex models
                    654:   than V1+V2. A lot of change to be done. Unstable.
                    655: 
1.137     brouard   656:   Revision 1.136  2010/04/26 20:30:53  brouard
                    657:   (Module): merging some libgsl code. Fixing computation
                    658:   of likelione (using inter/intrapolation if mle = 0) in order to
                    659:   get same likelihood as if mle=1.
                    660:   Some cleaning of code and comments added.
                    661: 
1.136     brouard   662:   Revision 1.135  2009/10/29 15:33:14  brouard
                    663:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    664: 
1.135     brouard   665:   Revision 1.134  2009/10/29 13:18:53  brouard
                    666:   (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
                    667: 
1.134     brouard   668:   Revision 1.133  2009/07/06 10:21:25  brouard
                    669:   just nforces
                    670: 
1.133     brouard   671:   Revision 1.132  2009/07/06 08:22:05  brouard
                    672:   Many tings
                    673: 
1.132     brouard   674:   Revision 1.131  2009/06/20 16:22:47  brouard
                    675:   Some dimensions resccaled
                    676: 
1.131     brouard   677:   Revision 1.130  2009/05/26 06:44:34  brouard
                    678:   (Module): Max Covariate is now set to 20 instead of 8. A
                    679:   lot of cleaning with variables initialized to 0. Trying to make
                    680:   V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
                    681: 
1.130     brouard   682:   Revision 1.129  2007/08/31 13:49:27  lievre
                    683:   Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
                    684: 
1.129     lievre    685:   Revision 1.128  2006/06/30 13:02:05  brouard
                    686:   (Module): Clarifications on computing e.j
                    687: 
1.128     brouard   688:   Revision 1.127  2006/04/28 18:11:50  brouard
                    689:   (Module): Yes the sum of survivors was wrong since
                    690:   imach-114 because nhstepm was no more computed in the age
                    691:   loop. Now we define nhstepma in the age loop.
                    692:   (Module): In order to speed up (in case of numerous covariates) we
                    693:   compute health expectancies (without variances) in a first step
                    694:   and then all the health expectancies with variances or standard
                    695:   deviation (needs data from the Hessian matrices) which slows the
                    696:   computation.
                    697:   In the future we should be able to stop the program is only health
                    698:   expectancies and graph are needed without standard deviations.
                    699: 
1.127     brouard   700:   Revision 1.126  2006/04/28 17:23:28  brouard
                    701:   (Module): Yes the sum of survivors was wrong since
                    702:   imach-114 because nhstepm was no more computed in the age
                    703:   loop. Now we define nhstepma in the age loop.
                    704:   Version 0.98h
                    705: 
1.126     brouard   706:   Revision 1.125  2006/04/04 15:20:31  lievre
                    707:   Errors in calculation of health expectancies. Age was not initialized.
                    708:   Forecasting file added.
                    709: 
                    710:   Revision 1.124  2006/03/22 17:13:53  lievre
                    711:   Parameters are printed with %lf instead of %f (more numbers after the comma).
                    712:   The log-likelihood is printed in the log file
                    713: 
                    714:   Revision 1.123  2006/03/20 10:52:43  brouard
                    715:   * imach.c (Module): <title> changed, corresponds to .htm file
                    716:   name. <head> headers where missing.
                    717: 
                    718:   * imach.c (Module): Weights can have a decimal point as for
                    719:   English (a comma might work with a correct LC_NUMERIC environment,
                    720:   otherwise the weight is truncated).
                    721:   Modification of warning when the covariates values are not 0 or
                    722:   1.
                    723:   Version 0.98g
                    724: 
                    725:   Revision 1.122  2006/03/20 09:45:41  brouard
                    726:   (Module): Weights can have a decimal point as for
                    727:   English (a comma might work with a correct LC_NUMERIC environment,
                    728:   otherwise the weight is truncated).
                    729:   Modification of warning when the covariates values are not 0 or
                    730:   1.
                    731:   Version 0.98g
                    732: 
                    733:   Revision 1.121  2006/03/16 17:45:01  lievre
                    734:   * imach.c (Module): Comments concerning covariates added
                    735: 
                    736:   * imach.c (Module): refinements in the computation of lli if
                    737:   status=-2 in order to have more reliable computation if stepm is
                    738:   not 1 month. Version 0.98f
                    739: 
                    740:   Revision 1.120  2006/03/16 15:10:38  lievre
                    741:   (Module): refinements in the computation of lli if
                    742:   status=-2 in order to have more reliable computation if stepm is
                    743:   not 1 month. Version 0.98f
                    744: 
                    745:   Revision 1.119  2006/03/15 17:42:26  brouard
                    746:   (Module): Bug if status = -2, the loglikelihood was
                    747:   computed as likelihood omitting the logarithm. Version O.98e
                    748: 
                    749:   Revision 1.118  2006/03/14 18:20:07  brouard
                    750:   (Module): varevsij Comments added explaining the second
                    751:   table of variances if popbased=1 .
                    752:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    753:   (Module): Function pstamp added
                    754:   (Module): Version 0.98d
                    755: 
                    756:   Revision 1.117  2006/03/14 17:16:22  brouard
                    757:   (Module): varevsij Comments added explaining the second
                    758:   table of variances if popbased=1 .
                    759:   (Module): Covariances of eij, ekl added, graphs fixed, new html link.
                    760:   (Module): Function pstamp added
                    761:   (Module): Version 0.98d
                    762: 
                    763:   Revision 1.116  2006/03/06 10:29:27  brouard
                    764:   (Module): Variance-covariance wrong links and
                    765:   varian-covariance of ej. is needed (Saito).
                    766: 
                    767:   Revision 1.115  2006/02/27 12:17:45  brouard
                    768:   (Module): One freematrix added in mlikeli! 0.98c
                    769: 
                    770:   Revision 1.114  2006/02/26 12:57:58  brouard
                    771:   (Module): Some improvements in processing parameter
                    772:   filename with strsep.
                    773: 
                    774:   Revision 1.113  2006/02/24 14:20:24  brouard
                    775:   (Module): Memory leaks checks with valgrind and:
                    776:   datafile was not closed, some imatrix were not freed and on matrix
                    777:   allocation too.
                    778: 
                    779:   Revision 1.112  2006/01/30 09:55:26  brouard
                    780:   (Module): Back to gnuplot.exe instead of wgnuplot.exe
                    781: 
                    782:   Revision 1.111  2006/01/25 20:38:18  brouard
                    783:   (Module): Lots of cleaning and bugs added (Gompertz)
                    784:   (Module): Comments can be added in data file. Missing date values
                    785:   can be a simple dot '.'.
                    786: 
                    787:   Revision 1.110  2006/01/25 00:51:50  brouard
                    788:   (Module): Lots of cleaning and bugs added (Gompertz)
                    789: 
                    790:   Revision 1.109  2006/01/24 19:37:15  brouard
                    791:   (Module): Comments (lines starting with a #) are allowed in data.
                    792: 
                    793:   Revision 1.108  2006/01/19 18:05:42  lievre
                    794:   Gnuplot problem appeared...
                    795:   To be fixed
                    796: 
                    797:   Revision 1.107  2006/01/19 16:20:37  brouard
                    798:   Test existence of gnuplot in imach path
                    799: 
                    800:   Revision 1.106  2006/01/19 13:24:36  brouard
                    801:   Some cleaning and links added in html output
                    802: 
                    803:   Revision 1.105  2006/01/05 20:23:19  lievre
                    804:   *** empty log message ***
                    805: 
                    806:   Revision 1.104  2005/09/30 16:11:43  lievre
                    807:   (Module): sump fixed, loop imx fixed, and simplifications.
                    808:   (Module): If the status is missing at the last wave but we know
                    809:   that the person is alive, then we can code his/her status as -2
                    810:   (instead of missing=-1 in earlier versions) and his/her
                    811:   contributions to the likelihood is 1 - Prob of dying from last
                    812:   health status (= 1-p13= p11+p12 in the easiest case of somebody in
                    813:   the healthy state at last known wave). Version is 0.98
                    814: 
                    815:   Revision 1.103  2005/09/30 15:54:49  lievre
                    816:   (Module): sump fixed, loop imx fixed, and simplifications.
                    817: 
                    818:   Revision 1.102  2004/09/15 17:31:30  brouard
                    819:   Add the possibility to read data file including tab characters.
                    820: 
                    821:   Revision 1.101  2004/09/15 10:38:38  brouard
                    822:   Fix on curr_time
                    823: 
                    824:   Revision 1.100  2004/07/12 18:29:06  brouard
                    825:   Add version for Mac OS X. Just define UNIX in Makefile
                    826: 
                    827:   Revision 1.99  2004/06/05 08:57:40  brouard
                    828:   *** empty log message ***
                    829: 
                    830:   Revision 1.98  2004/05/16 15:05:56  brouard
                    831:   New version 0.97 . First attempt to estimate force of mortality
                    832:   directly from the data i.e. without the need of knowing the health
                    833:   state at each age, but using a Gompertz model: log u =a + b*age .
                    834:   This is the basic analysis of mortality and should be done before any
                    835:   other analysis, in order to test if the mortality estimated from the
                    836:   cross-longitudinal survey is different from the mortality estimated
                    837:   from other sources like vital statistic data.
                    838: 
                    839:   The same imach parameter file can be used but the option for mle should be -3.
                    840: 
1.133     brouard   841:   Agnès, who wrote this part of the code, tried to keep most of the
1.126     brouard   842:   former routines in order to include the new code within the former code.
                    843: 
                    844:   The output is very simple: only an estimate of the intercept and of
                    845:   the slope with 95% confident intervals.
                    846: 
                    847:   Current limitations:
                    848:   A) Even if you enter covariates, i.e. with the
                    849:   model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
                    850:   B) There is no computation of Life Expectancy nor Life Table.
                    851: 
                    852:   Revision 1.97  2004/02/20 13:25:42  lievre
                    853:   Version 0.96d. Population forecasting command line is (temporarily)
                    854:   suppressed.
                    855: 
                    856:   Revision 1.96  2003/07/15 15:38:55  brouard
                    857:   * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
                    858:   rewritten within the same printf. Workaround: many printfs.
                    859: 
                    860:   Revision 1.95  2003/07/08 07:54:34  brouard
                    861:   * imach.c (Repository):
                    862:   (Repository): Using imachwizard code to output a more meaningful covariance
                    863:   matrix (cov(a12,c31) instead of numbers.
                    864: 
                    865:   Revision 1.94  2003/06/27 13:00:02  brouard
                    866:   Just cleaning
                    867: 
                    868:   Revision 1.93  2003/06/25 16:33:55  brouard
                    869:   (Module): On windows (cygwin) function asctime_r doesn't
                    870:   exist so I changed back to asctime which exists.
                    871:   (Module): Version 0.96b
                    872: 
                    873:   Revision 1.92  2003/06/25 16:30:45  brouard
                    874:   (Module): On windows (cygwin) function asctime_r doesn't
                    875:   exist so I changed back to asctime which exists.
                    876: 
                    877:   Revision 1.91  2003/06/25 15:30:29  brouard
                    878:   * imach.c (Repository): Duplicated warning errors corrected.
                    879:   (Repository): Elapsed time after each iteration is now output. It
                    880:   helps to forecast when convergence will be reached. Elapsed time
                    881:   is stamped in powell.  We created a new html file for the graphs
                    882:   concerning matrix of covariance. It has extension -cov.htm.
                    883: 
                    884:   Revision 1.90  2003/06/24 12:34:15  brouard
                    885:   (Module): Some bugs corrected for windows. Also, when
                    886:   mle=-1 a template is output in file "or"mypar.txt with the design
                    887:   of the covariance matrix to be input.
                    888: 
                    889:   Revision 1.89  2003/06/24 12:30:52  brouard
                    890:   (Module): Some bugs corrected for windows. Also, when
                    891:   mle=-1 a template is output in file "or"mypar.txt with the design
                    892:   of the covariance matrix to be input.
                    893: 
                    894:   Revision 1.88  2003/06/23 17:54:56  brouard
                    895:   * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
                    896: 
                    897:   Revision 1.87  2003/06/18 12:26:01  brouard
                    898:   Version 0.96
                    899: 
                    900:   Revision 1.86  2003/06/17 20:04:08  brouard
                    901:   (Module): Change position of html and gnuplot routines and added
                    902:   routine fileappend.
                    903: 
                    904:   Revision 1.85  2003/06/17 13:12:43  brouard
                    905:   * imach.c (Repository): Check when date of death was earlier that
                    906:   current date of interview. It may happen when the death was just
                    907:   prior to the death. In this case, dh was negative and likelihood
                    908:   was wrong (infinity). We still send an "Error" but patch by
                    909:   assuming that the date of death was just one stepm after the
                    910:   interview.
                    911:   (Repository): Because some people have very long ID (first column)
                    912:   we changed int to long in num[] and we added a new lvector for
                    913:   memory allocation. But we also truncated to 8 characters (left
                    914:   truncation)
                    915:   (Repository): No more line truncation errors.
                    916: 
                    917:   Revision 1.84  2003/06/13 21:44:43  brouard
                    918:   * imach.c (Repository): Replace "freqsummary" at a correct
                    919:   place. It differs from routine "prevalence" which may be called
                    920:   many times. Probs is memory consuming and must be used with
                    921:   parcimony.
                    922:   Version 0.95a3 (should output exactly the same maximization than 0.8a2)
                    923: 
                    924:   Revision 1.83  2003/06/10 13:39:11  lievre
                    925:   *** empty log message ***
                    926: 
                    927:   Revision 1.82  2003/06/05 15:57:20  brouard
                    928:   Add log in  imach.c and  fullversion number is now printed.
                    929: 
                    930: */
                    931: /*
                    932:    Interpolated Markov Chain
                    933: 
                    934:   Short summary of the programme:
                    935:   
1.227     brouard   936:   This program computes Healthy Life Expectancies or State-specific
                    937:   (if states aren't health statuses) Expectancies from
                    938:   cross-longitudinal data. Cross-longitudinal data consist in: 
                    939: 
                    940:   -1- a first survey ("cross") where individuals from different ages
                    941:   are interviewed on their health status or degree of disability (in
                    942:   the case of a health survey which is our main interest)
                    943: 
                    944:   -2- at least a second wave of interviews ("longitudinal") which
                    945:   measure each change (if any) in individual health status.  Health
                    946:   expectancies are computed from the time spent in each health state
                    947:   according to a model. More health states you consider, more time is
                    948:   necessary to reach the Maximum Likelihood of the parameters involved
                    949:   in the model.  The simplest model is the multinomial logistic model
                    950:   where pij is the probability to be observed in state j at the second
                    951:   wave conditional to be observed in state i at the first
                    952:   wave. Therefore the model is: log(pij/pii)= aij + bij*age+ cij*sex +
                    953:   etc , where 'age' is age and 'sex' is a covariate. If you want to
                    954:   have a more complex model than "constant and age", you should modify
                    955:   the program where the markup *Covariates have to be included here
                    956:   again* invites you to do it.  More covariates you add, slower the
1.126     brouard   957:   convergence.
                    958: 
                    959:   The advantage of this computer programme, compared to a simple
                    960:   multinomial logistic model, is clear when the delay between waves is not
                    961:   identical for each individual. Also, if a individual missed an
                    962:   intermediate interview, the information is lost, but taken into
                    963:   account using an interpolation or extrapolation.  
                    964: 
                    965:   hPijx is the probability to be observed in state i at age x+h
                    966:   conditional to the observed state i at age x. The delay 'h' can be
                    967:   split into an exact number (nh*stepm) of unobserved intermediate
                    968:   states. This elementary transition (by month, quarter,
                    969:   semester or year) is modelled as a multinomial logistic.  The hPx
                    970:   matrix is simply the matrix product of nh*stepm elementary matrices
                    971:   and the contribution of each individual to the likelihood is simply
                    972:   hPijx.
                    973: 
                    974:   Also this programme outputs the covariance matrix of the parameters but also
1.218     brouard   975:   of the life expectancies. It also computes the period (stable) prevalence.
                    976: 
                    977: Back prevalence and projections:
1.227     brouard   978: 
                    979:  - back_prevalence_limit(double *p, double **bprlim, double ageminpar,
                    980:    double agemaxpar, double ftolpl, int *ncvyearp, double
                    981:    dateprev1,double dateprev2, int firstpass, int lastpass, int
                    982:    mobilavproj)
                    983: 
                    984:     Computes the back prevalence limit for any combination of
                    985:     covariate values k at any age between ageminpar and agemaxpar and
                    986:     returns it in **bprlim. In the loops,
                    987: 
                    988:    - **bprevalim(**bprlim, ***mobaverage, nlstate, *p, age, **oldm,
                    989:        **savm, **dnewm, **doldm, **dsavm, ftolpl, ncvyearp, k);
                    990: 
                    991:    - hBijx Back Probability to be in state i at age x-h being in j at x
1.218     brouard   992:    Computes for any combination of covariates k and any age between bage and fage 
                    993:    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                    994:                        oldm=oldms;savm=savms;
1.227     brouard   995: 
1.267     brouard   996:    - hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);
1.218     brouard   997:      Computes the transition matrix starting at age 'age' over
                    998:      'nhstepm*hstepm*stepm' months (i.e. until
                    999:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
1.227     brouard  1000:      nhstepm*hstepm matrices. 
                   1001: 
                   1002:      Returns p3mat[i][j][h] after calling
                   1003:      p3mat[i][j][h]=matprod2(newm,
                   1004:      bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm,
                   1005:      dsavm,ij),\ 1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,
                   1006:      oldm);
1.226     brouard  1007: 
                   1008: Important routines
                   1009: 
                   1010: - func (or funcone), computes logit (pij) distinguishing
                   1011:   o fixed variables (single or product dummies or quantitative);
                   1012:   o varying variables by:
                   1013:    (1) wave (single, product dummies, quantitative), 
                   1014:    (2) by age (can be month) age (done), age*age (done), age*Vn where Vn can be:
                   1015:        % fixed dummy (treated) or quantitative (not done because time-consuming);
                   1016:        % varying dummy (not done) or quantitative (not done);
                   1017: - Tricode which tests the modality of dummy variables (in order to warn with wrong or empty modalities)
                   1018:   and returns the number of efficient covariates cptcoveff and modalities nbcode[Tvar[k]][1]= 0 and nbcode[Tvar[k]][2]= 1 usually.
                   1019: - printinghtml which outputs results like life expectancy in and from a state for a combination of modalities of dummy variables
                   1020:   o There are 2*cptcoveff combinations of (0,1) for cptcoveff variables. Outputting only combinations with people, éliminating 1 1 if
                   1021:     race White (0 0), Black vs White (1 0), Hispanic (0 1) and 1 1 being meaningless.
1.218     brouard  1022: 
1.226     brouard  1023: 
                   1024:   
1.133     brouard  1025:   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
                   1026:            Institut national d'études démographiques, Paris.
1.126     brouard  1027:   This software have been partly granted by Euro-REVES, a concerted action
                   1028:   from the European Union.
                   1029:   It is copyrighted identically to a GNU software product, ie programme and
                   1030:   software can be distributed freely for non commercial use. Latest version
                   1031:   can be accessed at http://euroreves.ined.fr/imach .
                   1032: 
                   1033:   Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
                   1034:   or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
                   1035:   
                   1036:   **********************************************************************/
                   1037: /*
                   1038:   main
                   1039:   read parameterfile
                   1040:   read datafile
                   1041:   concatwav
                   1042:   freqsummary
                   1043:   if (mle >= 1)
                   1044:     mlikeli
                   1045:   print results files
                   1046:   if mle==1 
                   1047:      computes hessian
                   1048:   read end of parameter file: agemin, agemax, bage, fage, estepm
                   1049:       begin-prev-date,...
                   1050:   open gnuplot file
                   1051:   open html file
1.145     brouard  1052:   period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
                   1053:    for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
                   1054:                                   | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
                   1055:     freexexit2 possible for memory heap.
                   1056: 
                   1057:   h Pij x                         | pij_nom  ficrestpij
                   1058:    # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
                   1059:        1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
                   1060:        1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
                   1061: 
                   1062:        1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
                   1063:        1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
                   1064:   variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
                   1065:    Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
                   1066:    Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
                   1067: 
1.126     brouard  1068:   forecasting if prevfcast==1 prevforecast call prevalence()
                   1069:   health expectancies
                   1070:   Variance-covariance of DFLE
                   1071:   prevalence()
                   1072:    movingaverage()
                   1073:   varevsij() 
                   1074:   if popbased==1 varevsij(,popbased)
                   1075:   total life expectancies
                   1076:   Variance of period (stable) prevalence
                   1077:  end
                   1078: */
                   1079: 
1.187     brouard  1080: /* #define DEBUG */
                   1081: /* #define DEBUGBRENT */
1.203     brouard  1082: /* #define DEBUGLINMIN */
                   1083: /* #define DEBUGHESS */
                   1084: #define DEBUGHESSIJ
1.224     brouard  1085: /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan) *\/ */
1.165     brouard  1086: #define POWELL /* Instead of NLOPT */
1.224     brouard  1087: #define POWELLNOF3INFF1TEST /* Skip test */
1.186     brouard  1088: /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
                   1089: /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
1.126     brouard  1090: 
                   1091: #include <math.h>
                   1092: #include <stdio.h>
                   1093: #include <stdlib.h>
                   1094: #include <string.h>
1.226     brouard  1095: #include <ctype.h>
1.159     brouard  1096: 
                   1097: #ifdef _WIN32
                   1098: #include <io.h>
1.172     brouard  1099: #include <windows.h>
                   1100: #include <tchar.h>
1.159     brouard  1101: #else
1.126     brouard  1102: #include <unistd.h>
1.159     brouard  1103: #endif
1.126     brouard  1104: 
                   1105: #include <limits.h>
                   1106: #include <sys/types.h>
1.171     brouard  1107: 
                   1108: #if defined(__GNUC__)
                   1109: #include <sys/utsname.h> /* Doesn't work on Windows */
                   1110: #endif
                   1111: 
1.126     brouard  1112: #include <sys/stat.h>
                   1113: #include <errno.h>
1.159     brouard  1114: /* extern int errno; */
1.126     brouard  1115: 
1.157     brouard  1116: /* #ifdef LINUX */
                   1117: /* #include <time.h> */
                   1118: /* #include "timeval.h" */
                   1119: /* #else */
                   1120: /* #include <sys/time.h> */
                   1121: /* #endif */
                   1122: 
1.126     brouard  1123: #include <time.h>
                   1124: 
1.136     brouard  1125: #ifdef GSL
                   1126: #include <gsl/gsl_errno.h>
                   1127: #include <gsl/gsl_multimin.h>
                   1128: #endif
                   1129: 
1.167     brouard  1130: 
1.162     brouard  1131: #ifdef NLOPT
                   1132: #include <nlopt.h>
                   1133: typedef struct {
                   1134:   double (* function)(double [] );
                   1135: } myfunc_data ;
                   1136: #endif
                   1137: 
1.126     brouard  1138: /* #include <libintl.h> */
                   1139: /* #define _(String) gettext (String) */
                   1140: 
1.251     brouard  1141: #define MAXLINE 2048 /* Was 256 and 1024. Overflow with 312 with 2 states and 4 covariates. Should be ok */
1.126     brouard  1142: 
                   1143: #define GNUPLOTPROGRAM "gnuplot"
                   1144: /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
                   1145: #define FILENAMELENGTH 132
                   1146: 
                   1147: #define        GLOCK_ERROR_NOPATH              -1      /* empty path */
                   1148: #define        GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
                   1149: 
1.144     brouard  1150: #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
                   1151: #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
1.126     brouard  1152: 
                   1153: #define NINTERVMAX 8
1.144     brouard  1154: #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
                   1155: #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
1.291     brouard  1156: #define NCOVMAX 20  /**< Maximum number of covariates, including generated covariates V1*V2 */
1.197     brouard  1157: #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.211     brouard  1158: /*#define decodtabm(h,k,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (k-1)) & 1) +1 : -1)*/
                   1159: #define decodtabm(h,k,cptcoveff) (((h-1) >> (k-1)) & 1) +1 
1.290     brouard  1160: /*#define MAXN 20000 */ /* Should by replaced by nobs, real number of observations and unlimited */
1.144     brouard  1161: #define YEARM 12. /**< Number of months per year */
1.218     brouard  1162: /* #define AGESUP 130 */
1.288     brouard  1163: /* #define AGESUP 150 */
                   1164: #define AGESUP 200
1.268     brouard  1165: #define AGEINF 0
1.218     brouard  1166: #define AGEMARGE 25 /* Marge for agemin and agemax for(iage=agemin-AGEMARGE; iage <= agemax+3+AGEMARGE; iage++) */
1.126     brouard  1167: #define AGEBASE 40
1.194     brouard  1168: #define AGEOVERFLOW 1.e20
1.164     brouard  1169: #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
1.157     brouard  1170: #ifdef _WIN32
                   1171: #define DIRSEPARATOR '\\'
                   1172: #define CHARSEPARATOR "\\"
                   1173: #define ODIRSEPARATOR '/'
                   1174: #else
1.126     brouard  1175: #define DIRSEPARATOR '/'
                   1176: #define CHARSEPARATOR "/"
                   1177: #define ODIRSEPARATOR '\\'
                   1178: #endif
                   1179: 
1.315   ! brouard  1180: /* $Id: imach.c,v 1.314 2022/04/13 17:43:09 brouard Exp $ */
1.126     brouard  1181: /* $State: Exp $ */
1.196     brouard  1182: #include "version.h"
                   1183: char version[]=__IMACH_VERSION__;
1.308     brouard  1184: char copyright[]="March 2021,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015-2020, Nihon University 2021, INED 2000-2021";
1.315   ! brouard  1185: char fullversion[]="$Revision: 1.314 $ $Date: 2022/04/13 17:43:09 $"; 
1.126     brouard  1186: char strstart[80];
                   1187: char optionfilext[10], optionfilefiname[FILENAMELENGTH];
1.130     brouard  1188: int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
1.187     brouard  1189: int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
1.145     brouard  1190: /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
                   1191: int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
                   1192: int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
1.225     brouard  1193: int cptcovs=0; /**< cptcovs number of simple covariates in the model V2+V1 =2 */
                   1194: int cptcovsnq=0; /**< cptcovsnq number of simple covariates in the model but non quantitative V2+V1 =2 */
1.145     brouard  1195: int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
                   1196: int cptcovprodnoage=0; /**< Number of covariate products without age */   
                   1197: int cptcoveff=0; /* Total number of covariates to vary for printing results */
1.233     brouard  1198: int ncovf=0; /* Total number of effective fixed covariates (dummy or quantitative) in the model */
                   1199: int ncovv=0; /* Total number of effective (wave) varying covariates (dummy or quantitative) in the model */
1.232     brouard  1200: int ncova=0; /* Total number of effective (wave and stepm) varying with age covariates (dummy of quantitative) in the model */
1.234     brouard  1201: int nsd=0; /**< Total number of single dummy variables (output) */
                   1202: int nsq=0; /**< Total number of single quantitative variables (output) */
1.232     brouard  1203: int ncoveff=0; /* Total number of effective fixed dummy covariates in the model */
1.225     brouard  1204: int nqfveff=0; /**< nqfveff Number of Quantitative Fixed Variables Effective */
1.224     brouard  1205: int ntveff=0; /**< ntveff number of effective time varying variables */
                   1206: int nqtveff=0; /**< ntqveff number of effective time varying quantitative variables */
1.145     brouard  1207: int cptcov=0; /* Working variable */
1.290     brouard  1208: int nobs=10;  /* Number of observations in the data lastobs-firstobs */
1.218     brouard  1209: int ncovcombmax=NCOVMAX; /* Maximum calculated number of covariate combination = pow(2, cptcoveff) */
1.302     brouard  1210: int npar=NPARMAX; /* Number of parameters (nlstate+ndeath-1)*nlstate*ncovmodel; */
1.126     brouard  1211: int nlstate=2; /* Number of live states */
                   1212: int ndeath=1; /* Number of dead states */
1.130     brouard  1213: int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
1.223     brouard  1214: int  nqv=0, ntv=0, nqtv=0;    /* Total number of quantitative variables, time variable (dummy), quantitative and time variable */ 
1.126     brouard  1215: int popbased=0;
                   1216: 
                   1217: int *wav; /* Number of waves for this individuual 0 is possible */
1.130     brouard  1218: int maxwav=0; /* Maxim number of waves */
                   1219: int jmin=0, jmax=0; /* min, max spacing between 2 waves */
                   1220: int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
                   1221: int gipmx=0, gsw=0; /* Global variables on the number of contributions 
1.126     brouard  1222:                   to the likelihood and the sum of weights (done by funcone)*/
1.130     brouard  1223: int mle=1, weightopt=0;
1.126     brouard  1224: int **mw; /* mw[mi][i] is number of the mi wave for this individual */
                   1225: int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
                   1226: int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
                   1227:           * wave mi and wave mi+1 is not an exact multiple of stepm. */
1.162     brouard  1228: int countcallfunc=0;  /* Count the number of calls to func */
1.230     brouard  1229: int selected(int kvar); /* Is covariate kvar selected for printing results */
                   1230: 
1.130     brouard  1231: double jmean=1; /* Mean space between 2 waves */
1.145     brouard  1232: double **matprod2(); /* test */
1.126     brouard  1233: double **oldm, **newm, **savm; /* Working pointers to matrices */
                   1234: double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
1.218     brouard  1235: double  **ddnewms, **ddoldms, **ddsavms; /* for freeing later */
                   1236: 
1.136     brouard  1237: /*FILE *fic ; */ /* Used in readdata only */
1.217     brouard  1238: FILE *ficpar, *ficparo,*ficres, *ficresp, *ficresphtm, *ficresphtmfr, *ficrespl, *ficresplb,*ficrespij, *ficrespijb, *ficrest,*ficresf, *ficresfb,*ficrespop;
1.126     brouard  1239: FILE *ficlog, *ficrespow;
1.130     brouard  1240: int globpr=0; /* Global variable for printing or not */
1.126     brouard  1241: double fretone; /* Only one call to likelihood */
1.130     brouard  1242: long ipmx=0; /* Number of contributions */
1.126     brouard  1243: double sw; /* Sum of weights */
                   1244: char filerespow[FILENAMELENGTH];
                   1245: char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
                   1246: FILE *ficresilk;
                   1247: FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
                   1248: FILE *ficresprobmorprev;
                   1249: FILE *fichtm, *fichtmcov; /* Html File */
                   1250: FILE *ficreseij;
                   1251: char filerese[FILENAMELENGTH];
                   1252: FILE *ficresstdeij;
                   1253: char fileresstde[FILENAMELENGTH];
                   1254: FILE *ficrescveij;
                   1255: char filerescve[FILENAMELENGTH];
                   1256: FILE  *ficresvij;
                   1257: char fileresv[FILENAMELENGTH];
1.269     brouard  1258: 
1.126     brouard  1259: char title[MAXLINE];
1.234     brouard  1260: char model[MAXLINE]; /**< The model line */
1.217     brouard  1261: char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH],  fileresplb[FILENAMELENGTH];
1.126     brouard  1262: char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
                   1263: char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
                   1264: char command[FILENAMELENGTH];
                   1265: int  outcmd=0;
                   1266: 
1.217     brouard  1267: char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filerespijb[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
1.202     brouard  1268: char fileresu[FILENAMELENGTH]; /* fileres without r in front */
1.126     brouard  1269: char filelog[FILENAMELENGTH]; /* Log file */
                   1270: char filerest[FILENAMELENGTH];
                   1271: char fileregp[FILENAMELENGTH];
                   1272: char popfile[FILENAMELENGTH];
                   1273: 
                   1274: char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
                   1275: 
1.157     brouard  1276: /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
                   1277: /* struct timezone tzp; */
                   1278: /* extern int gettimeofday(); */
                   1279: struct tm tml, *gmtime(), *localtime();
                   1280: 
                   1281: extern time_t time();
                   1282: 
                   1283: struct tm start_time, end_time, curr_time, last_time, forecast_time;
                   1284: time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
                   1285: struct tm tm;
                   1286: 
1.126     brouard  1287: char strcurr[80], strfor[80];
                   1288: 
                   1289: char *endptr;
                   1290: long lval;
                   1291: double dval;
                   1292: 
                   1293: #define NR_END 1
                   1294: #define FREE_ARG char*
                   1295: #define FTOL 1.0e-10
                   1296: 
                   1297: #define NRANSI 
1.240     brouard  1298: #define ITMAX 200
                   1299: #define ITPOWMAX 20 /* This is now multiplied by the number of parameters */ 
1.126     brouard  1300: 
                   1301: #define TOL 2.0e-4 
                   1302: 
                   1303: #define CGOLD 0.3819660 
                   1304: #define ZEPS 1.0e-10 
                   1305: #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
                   1306: 
                   1307: #define GOLD 1.618034 
                   1308: #define GLIMIT 100.0 
                   1309: #define TINY 1.0e-20 
                   1310: 
                   1311: static double maxarg1,maxarg2;
                   1312: #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
                   1313: #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
                   1314:   
                   1315: #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                   1316: #define rint(a) floor(a+0.5)
1.166     brouard  1317: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
1.183     brouard  1318: #define mytinydouble 1.0e-16
1.166     brouard  1319: /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
                   1320: /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
                   1321: /* static double dsqrarg; */
                   1322: /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
1.126     brouard  1323: static double sqrarg;
                   1324: #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
                   1325: #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
                   1326: int agegomp= AGEGOMP;
                   1327: 
                   1328: int imx; 
                   1329: int stepm=1;
                   1330: /* Stepm, step in month: minimum step interpolation*/
                   1331: 
                   1332: int estepm;
                   1333: /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
                   1334: 
                   1335: int m,nb;
                   1336: long *num;
1.197     brouard  1337: int firstpass=0, lastpass=4,*cod, *cens;
1.192     brouard  1338: int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
                   1339:                   covariate for which somebody answered excluding 
                   1340:                   undefined. Usually 2: 0 and 1. */
                   1341: int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
                   1342:                             covariate for which somebody answered including 
                   1343:                             undefined. Usually 3: -1, 0 and 1. */
1.126     brouard  1344: double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
1.218     brouard  1345: double **pmmij, ***probs; /* Global pointer */
1.219     brouard  1346: double ***mobaverage, ***mobaverages; /* New global variable */
1.126     brouard  1347: double *ageexmed,*agecens;
                   1348: double dateintmean=0;
1.296     brouard  1349:   double anprojd, mprojd, jprojd; /* For eventual projections */
                   1350:   double anprojf, mprojf, jprojf;
1.126     brouard  1351: 
1.296     brouard  1352:   double anbackd, mbackd, jbackd; /* For eventual backprojections */
                   1353:   double anbackf, mbackf, jbackf;
                   1354:   double jintmean,mintmean,aintmean;  
1.126     brouard  1355: double *weight;
                   1356: int **s; /* Status */
1.141     brouard  1357: double *agedc;
1.145     brouard  1358: double  **covar; /**< covar[j,i], value of jth covariate for individual i,
1.141     brouard  1359:                  * covar=matrix(0,NCOVMAX,1,n); 
1.187     brouard  1360:                  * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
1.268     brouard  1361: double **coqvar; /* Fixed quantitative covariate nqv */
                   1362: double ***cotvar; /* Time varying covariate ntv */
1.225     brouard  1363: double ***cotqvar; /* Time varying quantitative covariate itqv */
1.141     brouard  1364: double  idx; 
                   1365: int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
1.234     brouard  1366: /*           V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1367: /*k          1  2   3   4     5    6    7     8    9 */
                   1368: /*Tvar[k]=   5  4   3   6     5    2    7     1    1 */
                   1369: /* Tndvar[k]    1   2   3               4          5 */
                   1370: /*TDvar         4   3   6               7          1 */ /* For outputs only; combination of dummies fixed or varying */
                   1371: /* Tns[k]    1  2   2              4               5 */ /* Number of single cova */
                   1372: /* TvarsD[k]    1   2                              3 */ /* Number of single dummy cova */
                   1373: /* TvarsDind    2   3                              9 */ /* position K of single dummy cova */
                   1374: /* TvarsQ[k] 1                     2                 */ /* Number of single quantitative cova */
                   1375: /* TvarsQind 1                     6                 */ /* position K of single quantitative cova */
                   1376: /* Tprod[i]=k           4               7            */
                   1377: /* Tage[i]=k                  5               8      */
                   1378: /* */
                   1379: /* Type                    */
                   1380: /* V         1  2  3  4  5 */
                   1381: /*           F  F  V  V  V */
                   1382: /*           D  Q  D  D  Q */
                   1383: /*                         */
                   1384: int *TvarsD;
                   1385: int *TvarsDind;
                   1386: int *TvarsQ;
                   1387: int *TvarsQind;
                   1388: 
1.235     brouard  1389: #define MAXRESULTLINES 10
                   1390: int nresult=0;
1.258     brouard  1391: int parameterline=0; /* # of the parameter (type) line */
1.235     brouard  1392: int TKresult[MAXRESULTLINES];
1.237     brouard  1393: int Tresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
                   1394: int Tinvresult[MAXRESULTLINES][NCOVMAX];/* For dummy variable , value (output) */
1.235     brouard  1395: int Tvresult[MAXRESULTLINES][NCOVMAX]; /* For dummy variable , variable # (output) */
                   1396: double Tqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.237     brouard  1397: double Tqinvresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , value (output) */
1.235     brouard  1398: int Tvqresult[MAXRESULTLINES][NCOVMAX]; /* For quantitative variable , variable # (output) */
                   1399: 
1.234     brouard  1400: /* int *TDvar; /\**< TDvar[1]=4,  TDvarF[2]=3, TDvar[3]=6  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 *\/ */
1.232     brouard  1401: int *TvarF; /**< TvarF[1]=Tvar[6]=2,  TvarF[2]=Tvar[7]=7, TvarF[3]=Tvar[9]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1402: int *TvarFind; /**< TvarFind[1]=6,  TvarFind[2]=7, Tvarind[3]=9  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1403: int *TvarV; /**< TvarV[1]=Tvar[1]=5, TvarV[2]=Tvar[2]=4  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1404: int *TvarVind; /**< TvarVind[1]=1, TvarVind[2]=2  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1405: int *TvarA; /**< TvarA[1]=Tvar[5]=5, TvarA[2]=Tvar[8]=1  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1406: int *TvarAind; /**< TvarindA[1]=5, TvarAind[2]=8  in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  1407: int *TvarFD; /**< TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1408: int *TvarFDind; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   1409: int *TvarFQ; /* TvarFQ[1]=V2 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1410: int *TvarFQind; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1411: int *TvarVD; /* TvarVD[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1412: int *TvarVDind; /* TvarVDind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
                   1413: int *TvarVQ; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1414: int *TvarVQind; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   1415: 
1.230     brouard  1416: int *Tvarsel; /**< Selected covariates for output */
                   1417: double *Tvalsel; /**< Selected modality value of covariate for output */
1.226     brouard  1418: int *Typevar; /**< 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product */
1.227     brouard  1419: int *Fixed; /** Fixed[k] 0=fixed, 1 varying, 2 fixed with age product, 3 varying with age product */ 
                   1420: int *Dummy; /** Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product */ 
1.238     brouard  1421: int *DummyV; /** Dummy[v] 0=dummy (0 1), 1 quantitative */
                   1422: int *FixedV; /** FixedV[v] 0 fixed, 1 varying */
1.197     brouard  1423: int *Tage;
1.227     brouard  1424: int anyvaryingduminmodel=0; /**< Any varying dummy in Model=1 yes, 0 no, to avoid a loop on waves in freq */ 
1.228     brouard  1425: int *Tmodelind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.230     brouard  1426: int *TmodelInvind; /** Tmodelind[Tvaraff[3]]=9 for V1 position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/ 
                   1427: int *TmodelInvQind; /** Tmodelqind[1]=1 for V5(quantitative varying) position,Tvaraff[1]@9={4, 3, 1, 0, 0, 0, 0, 0, 0}, model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1  */
1.145     brouard  1428: int *Ndum; /** Freq of modality (tricode */
1.200     brouard  1429: /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
1.227     brouard  1430: int **Tvard;
                   1431: int *Tprod;/**< Gives the k position of the k1 product */
1.238     brouard  1432: /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3  */
1.227     brouard  1433: int *Tposprod; /**< Gives the k1 product from the k position */
1.238     brouard  1434:    /* if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2) */
                   1435:    /* Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5(V3*V2)]=2 (2nd product without age) */
1.227     brouard  1436: int cptcovprod, *Tvaraff, *invalidvarcomb;
1.126     brouard  1437: double *lsurv, *lpop, *tpop;
                   1438: 
1.231     brouard  1439: #define FD 1; /* Fixed dummy covariate */
                   1440: #define FQ 2; /* Fixed quantitative covariate */
                   1441: #define FP 3; /* Fixed product covariate */
                   1442: #define FPDD 7; /* Fixed product dummy*dummy covariate */
                   1443: #define FPDQ 8; /* Fixed product dummy*quantitative covariate */
                   1444: #define FPQQ 9; /* Fixed product quantitative*quantitative covariate */
                   1445: #define VD 10; /* Varying dummy covariate */
                   1446: #define VQ 11; /* Varying quantitative covariate */
                   1447: #define VP 12; /* Varying product covariate */
                   1448: #define VPDD 13; /* Varying product dummy*dummy covariate */
                   1449: #define VPDQ 14; /* Varying product dummy*quantitative covariate */
                   1450: #define VPQQ 15; /* Varying product quantitative*quantitative covariate */
                   1451: #define APFD 16; /* Age product * fixed dummy covariate */
                   1452: #define APFQ 17; /* Age product * fixed quantitative covariate */
                   1453: #define APVD 18; /* Age product * varying dummy covariate */
                   1454: #define APVQ 19; /* Age product * varying quantitative covariate */
                   1455: 
                   1456: #define FTYPE 1; /* Fixed covariate */
                   1457: #define VTYPE 2; /* Varying covariate (loop in wave) */
                   1458: #define ATYPE 2; /* Age product covariate (loop in dh within wave)*/
                   1459: 
                   1460: struct kmodel{
                   1461:        int maintype; /* main type */
                   1462:        int subtype; /* subtype */
                   1463: };
                   1464: struct kmodel modell[NCOVMAX];
                   1465: 
1.143     brouard  1466: double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
                   1467: double ftolhess; /**< Tolerance for computing hessian */
1.126     brouard  1468: 
                   1469: /**************** split *************************/
                   1470: static int split( char *path, char *dirc, char *name, char *ext, char *finame )
                   1471: {
                   1472:   /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
                   1473:      the name of the file (name), its extension only (ext) and its first part of the name (finame)
                   1474:   */ 
                   1475:   char *ss;                            /* pointer */
1.186     brouard  1476:   int  l1=0, l2=0;                             /* length counters */
1.126     brouard  1477: 
                   1478:   l1 = strlen(path );                  /* length of path */
                   1479:   if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1480:   ss= strrchr( path, DIRSEPARATOR );           /* find last / */
                   1481:   if ( ss == NULL ) {                  /* no directory, so determine current directory */
                   1482:     strcpy( name, path );              /* we got the fullname name because no directory */
                   1483:     /*if(strrchr(path, ODIRSEPARATOR )==NULL)
                   1484:       printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
                   1485:     /* get current working directory */
                   1486:     /*    extern  char* getcwd ( char *buf , int len);*/
1.184     brouard  1487: #ifdef WIN32
                   1488:     if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
                   1489: #else
                   1490:        if (getcwd(dirc, FILENAME_MAX) == NULL) {
                   1491: #endif
1.126     brouard  1492:       return( GLOCK_ERROR_GETCWD );
                   1493:     }
                   1494:     /* got dirc from getcwd*/
                   1495:     printf(" DIRC = %s \n",dirc);
1.205     brouard  1496:   } else {                             /* strip directory from path */
1.126     brouard  1497:     ss++;                              /* after this, the filename */
                   1498:     l2 = strlen( ss );                 /* length of filename */
                   1499:     if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
                   1500:     strcpy( name, ss );                /* save file name */
                   1501:     strncpy( dirc, path, l1 - l2 );    /* now the directory */
1.186     brouard  1502:     dirc[l1-l2] = '\0';                        /* add zero */
1.126     brouard  1503:     printf(" DIRC2 = %s \n",dirc);
                   1504:   }
                   1505:   /* We add a separator at the end of dirc if not exists */
                   1506:   l1 = strlen( dirc );                 /* length of directory */
                   1507:   if( dirc[l1-1] != DIRSEPARATOR ){
                   1508:     dirc[l1] =  DIRSEPARATOR;
                   1509:     dirc[l1+1] = 0; 
                   1510:     printf(" DIRC3 = %s \n",dirc);
                   1511:   }
                   1512:   ss = strrchr( name, '.' );           /* find last / */
                   1513:   if (ss >0){
                   1514:     ss++;
                   1515:     strcpy(ext,ss);                    /* save extension */
                   1516:     l1= strlen( name);
                   1517:     l2= strlen(ss)+1;
                   1518:     strncpy( finame, name, l1-l2);
                   1519:     finame[l1-l2]= 0;
                   1520:   }
                   1521: 
                   1522:   return( 0 );                         /* we're done */
                   1523: }
                   1524: 
                   1525: 
                   1526: /******************************************/
                   1527: 
                   1528: void replace_back_to_slash(char *s, char*t)
                   1529: {
                   1530:   int i;
                   1531:   int lg=0;
                   1532:   i=0;
                   1533:   lg=strlen(t);
                   1534:   for(i=0; i<= lg; i++) {
                   1535:     (s[i] = t[i]);
                   1536:     if (t[i]== '\\') s[i]='/';
                   1537:   }
                   1538: }
                   1539: 
1.132     brouard  1540: char *trimbb(char *out, char *in)
1.137     brouard  1541: { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
1.132     brouard  1542:   char *s;
                   1543:   s=out;
                   1544:   while (*in != '\0'){
1.137     brouard  1545:     while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
1.132     brouard  1546:       in++;
                   1547:     }
                   1548:     *out++ = *in++;
                   1549:   }
                   1550:   *out='\0';
                   1551:   return s;
                   1552: }
                   1553: 
1.187     brouard  1554: /* char *substrchaine(char *out, char *in, char *chain) */
                   1555: /* { */
                   1556: /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
                   1557: /*   char *s, *t; */
                   1558: /*   t=in;s=out; */
                   1559: /*   while ((*in != *chain) && (*in != '\0')){ */
                   1560: /*     *out++ = *in++; */
                   1561: /*   } */
                   1562: 
                   1563: /*   /\* *in matches *chain *\/ */
                   1564: /*   while ((*in++ == *chain++) && (*in != '\0')){ */
                   1565: /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1566: /*   } */
                   1567: /*   in--; chain--; */
                   1568: /*   while ( (*in != '\0')){ */
                   1569: /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1570: /*     *out++ = *in++; */
                   1571: /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
                   1572: /*   } */
                   1573: /*   *out='\0'; */
                   1574: /*   out=s; */
                   1575: /*   return out; */
                   1576: /* } */
                   1577: char *substrchaine(char *out, char *in, char *chain)
                   1578: {
                   1579:   /* Substract chain 'chain' from 'in', return and output 'out' */
                   1580:   /* in="V1+V1*age+age*age+V2", chain="age*age" */
                   1581: 
                   1582:   char *strloc;
                   1583: 
                   1584:   strcpy (out, in); 
                   1585:   strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
                   1586:   printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
                   1587:   if(strloc != NULL){ 
                   1588:     /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
                   1589:     memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
                   1590:     /* strcpy (strloc, strloc +strlen(chain));*/
                   1591:   }
                   1592:   printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
                   1593:   return out;
                   1594: }
                   1595: 
                   1596: 
1.145     brouard  1597: char *cutl(char *blocc, char *alocc, char *in, char occ)
                   1598: {
1.187     brouard  1599:   /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
1.145     brouard  1600:      and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
1.310     brouard  1601:      gives alocc="abcdef" and blocc="ghi2j".
1.145     brouard  1602:      If occ is not found blocc is null and alocc is equal to in. Returns blocc
                   1603:   */
1.160     brouard  1604:   char *s, *t;
1.145     brouard  1605:   t=in;s=in;
                   1606:   while ((*in != occ) && (*in != '\0')){
                   1607:     *alocc++ = *in++;
                   1608:   }
                   1609:   if( *in == occ){
                   1610:     *(alocc)='\0';
                   1611:     s=++in;
                   1612:   }
                   1613:  
                   1614:   if (s == t) {/* occ not found */
                   1615:     *(alocc-(in-s))='\0';
                   1616:     in=s;
                   1617:   }
                   1618:   while ( *in != '\0'){
                   1619:     *blocc++ = *in++;
                   1620:   }
                   1621: 
                   1622:   *blocc='\0';
                   1623:   return t;
                   1624: }
1.137     brouard  1625: char *cutv(char *blocc, char *alocc, char *in, char occ)
                   1626: {
1.187     brouard  1627:   /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
1.137     brouard  1628:      and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
                   1629:      gives blocc="abcdef2ghi" and alocc="j".
                   1630:      If occ is not found blocc is null and alocc is equal to in. Returns alocc
                   1631:   */
                   1632:   char *s, *t;
                   1633:   t=in;s=in;
                   1634:   while (*in != '\0'){
                   1635:     while( *in == occ){
                   1636:       *blocc++ = *in++;
                   1637:       s=in;
                   1638:     }
                   1639:     *blocc++ = *in++;
                   1640:   }
                   1641:   if (s == t) /* occ not found */
                   1642:     *(blocc-(in-s))='\0';
                   1643:   else
                   1644:     *(blocc-(in-s)-1)='\0';
                   1645:   in=s;
                   1646:   while ( *in != '\0'){
                   1647:     *alocc++ = *in++;
                   1648:   }
                   1649: 
                   1650:   *alocc='\0';
                   1651:   return s;
                   1652: }
                   1653: 
1.126     brouard  1654: int nbocc(char *s, char occ)
                   1655: {
                   1656:   int i,j=0;
                   1657:   int lg=20;
                   1658:   i=0;
                   1659:   lg=strlen(s);
                   1660:   for(i=0; i<= lg; i++) {
1.234     brouard  1661:     if  (s[i] == occ ) j++;
1.126     brouard  1662:   }
                   1663:   return j;
                   1664: }
                   1665: 
1.137     brouard  1666: /* void cutv(char *u,char *v, char*t, char occ) */
                   1667: /* { */
                   1668: /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
                   1669: /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
                   1670: /*      gives u="abcdef2ghi" and v="j" *\/ */
                   1671: /*   int i,lg,j,p=0; */
                   1672: /*   i=0; */
                   1673: /*   lg=strlen(t); */
                   1674: /*   for(j=0; j<=lg-1; j++) { */
                   1675: /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
                   1676: /*   } */
1.126     brouard  1677: 
1.137     brouard  1678: /*   for(j=0; j<p; j++) { */
                   1679: /*     (u[j] = t[j]); */
                   1680: /*   } */
                   1681: /*      u[p]='\0'; */
1.126     brouard  1682: 
1.137     brouard  1683: /*    for(j=0; j<= lg; j++) { */
                   1684: /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
                   1685: /*   } */
                   1686: /* } */
1.126     brouard  1687: 
1.160     brouard  1688: #ifdef _WIN32
                   1689: char * strsep(char **pp, const char *delim)
                   1690: {
                   1691:   char *p, *q;
                   1692:          
                   1693:   if ((p = *pp) == NULL)
                   1694:     return 0;
                   1695:   if ((q = strpbrk (p, delim)) != NULL)
                   1696:   {
                   1697:     *pp = q + 1;
                   1698:     *q = '\0';
                   1699:   }
                   1700:   else
                   1701:     *pp = 0;
                   1702:   return p;
                   1703: }
                   1704: #endif
                   1705: 
1.126     brouard  1706: /********************** nrerror ********************/
                   1707: 
                   1708: void nrerror(char error_text[])
                   1709: {
                   1710:   fprintf(stderr,"ERREUR ...\n");
                   1711:   fprintf(stderr,"%s\n",error_text);
                   1712:   exit(EXIT_FAILURE);
                   1713: }
                   1714: /*********************** vector *******************/
                   1715: double *vector(int nl, int nh)
                   1716: {
                   1717:   double *v;
                   1718:   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
                   1719:   if (!v) nrerror("allocation failure in vector");
                   1720:   return v-nl+NR_END;
                   1721: }
                   1722: 
                   1723: /************************ free vector ******************/
                   1724: void free_vector(double*v, int nl, int nh)
                   1725: {
                   1726:   free((FREE_ARG)(v+nl-NR_END));
                   1727: }
                   1728: 
                   1729: /************************ivector *******************************/
                   1730: int *ivector(long nl,long nh)
                   1731: {
                   1732:   int *v;
                   1733:   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
                   1734:   if (!v) nrerror("allocation failure in ivector");
                   1735:   return v-nl+NR_END;
                   1736: }
                   1737: 
                   1738: /******************free ivector **************************/
                   1739: void free_ivector(int *v, long nl, long nh)
                   1740: {
                   1741:   free((FREE_ARG)(v+nl-NR_END));
                   1742: }
                   1743: 
                   1744: /************************lvector *******************************/
                   1745: long *lvector(long nl,long nh)
                   1746: {
                   1747:   long *v;
                   1748:   v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
                   1749:   if (!v) nrerror("allocation failure in ivector");
                   1750:   return v-nl+NR_END;
                   1751: }
                   1752: 
                   1753: /******************free lvector **************************/
                   1754: void free_lvector(long *v, long nl, long nh)
                   1755: {
                   1756:   free((FREE_ARG)(v+nl-NR_END));
                   1757: }
                   1758: 
                   1759: /******************* imatrix *******************************/
                   1760: int **imatrix(long nrl, long nrh, long ncl, long nch) 
                   1761:      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
                   1762: { 
                   1763:   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
                   1764:   int **m; 
                   1765:   
                   1766:   /* allocate pointers to rows */ 
                   1767:   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
                   1768:   if (!m) nrerror("allocation failure 1 in matrix()"); 
                   1769:   m += NR_END; 
                   1770:   m -= nrl; 
                   1771:   
                   1772:   
                   1773:   /* allocate rows and set pointers to them */ 
                   1774:   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
                   1775:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
                   1776:   m[nrl] += NR_END; 
                   1777:   m[nrl] -= ncl; 
                   1778:   
                   1779:   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
                   1780:   
                   1781:   /* return pointer to array of pointers to rows */ 
                   1782:   return m; 
                   1783: } 
                   1784: 
                   1785: /****************** free_imatrix *************************/
                   1786: void free_imatrix(m,nrl,nrh,ncl,nch)
                   1787:       int **m;
                   1788:       long nch,ncl,nrh,nrl; 
                   1789:      /* free an int matrix allocated by imatrix() */ 
                   1790: { 
                   1791:   free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
                   1792:   free((FREE_ARG) (m+nrl-NR_END)); 
                   1793: } 
                   1794: 
                   1795: /******************* matrix *******************************/
                   1796: double **matrix(long nrl, long nrh, long ncl, long nch)
                   1797: {
                   1798:   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
                   1799:   double **m;
                   1800: 
                   1801:   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1802:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1803:   m += NR_END;
                   1804:   m -= nrl;
                   1805: 
                   1806:   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1807:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1808:   m[nrl] += NR_END;
                   1809:   m[nrl] -= ncl;
                   1810: 
                   1811:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1812:   return m;
1.145     brouard  1813:   /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
                   1814: m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
                   1815: that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
1.126     brouard  1816:    */
                   1817: }
                   1818: 
                   1819: /*************************free matrix ************************/
                   1820: void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
                   1821: {
                   1822:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1823:   free((FREE_ARG)(m+nrl-NR_END));
                   1824: }
                   1825: 
                   1826: /******************* ma3x *******************************/
                   1827: double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
                   1828: {
                   1829:   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
                   1830:   double ***m;
                   1831: 
                   1832:   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
                   1833:   if (!m) nrerror("allocation failure 1 in matrix()");
                   1834:   m += NR_END;
                   1835:   m -= nrl;
                   1836: 
                   1837:   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
                   1838:   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
                   1839:   m[nrl] += NR_END;
                   1840:   m[nrl] -= ncl;
                   1841: 
                   1842:   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
                   1843: 
                   1844:   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
                   1845:   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
                   1846:   m[nrl][ncl] += NR_END;
                   1847:   m[nrl][ncl] -= nll;
                   1848:   for (j=ncl+1; j<=nch; j++) 
                   1849:     m[nrl][j]=m[nrl][j-1]+nlay;
                   1850:   
                   1851:   for (i=nrl+1; i<=nrh; i++) {
                   1852:     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
                   1853:     for (j=ncl+1; j<=nch; j++) 
                   1854:       m[i][j]=m[i][j-1]+nlay;
                   1855:   }
                   1856:   return m; 
                   1857:   /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
                   1858:            &(m[i][j][k]) <=> *((*(m+i) + j)+k)
                   1859:   */
                   1860: }
                   1861: 
                   1862: /*************************free ma3x ************************/
                   1863: void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
                   1864: {
                   1865:   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
                   1866:   free((FREE_ARG)(m[nrl]+ncl-NR_END));
                   1867:   free((FREE_ARG)(m+nrl-NR_END));
                   1868: }
                   1869: 
                   1870: /*************** function subdirf ***********/
                   1871: char *subdirf(char fileres[])
                   1872: {
                   1873:   /* Caution optionfilefiname is hidden */
                   1874:   strcpy(tmpout,optionfilefiname);
                   1875:   strcat(tmpout,"/"); /* Add to the right */
                   1876:   strcat(tmpout,fileres);
                   1877:   return tmpout;
                   1878: }
                   1879: 
                   1880: /*************** function subdirf2 ***********/
                   1881: char *subdirf2(char fileres[], char *preop)
                   1882: {
1.314     brouard  1883:   /* Example subdirf2(optionfilefiname,"FB_") with optionfilefiname="texte", result="texte/FB_texte"
                   1884:  Errors in subdirf, 2, 3 while printing tmpout is
1.315   ! brouard  1885:  rewritten within the same printf. Workaround: many printfs */
1.126     brouard  1886:   /* Caution optionfilefiname is hidden */
                   1887:   strcpy(tmpout,optionfilefiname);
                   1888:   strcat(tmpout,"/");
                   1889:   strcat(tmpout,preop);
                   1890:   strcat(tmpout,fileres);
                   1891:   return tmpout;
                   1892: }
                   1893: 
                   1894: /*************** function subdirf3 ***********/
                   1895: char *subdirf3(char fileres[], char *preop, char *preop2)
                   1896: {
                   1897:   
                   1898:   /* Caution optionfilefiname is hidden */
                   1899:   strcpy(tmpout,optionfilefiname);
                   1900:   strcat(tmpout,"/");
                   1901:   strcat(tmpout,preop);
                   1902:   strcat(tmpout,preop2);
                   1903:   strcat(tmpout,fileres);
                   1904:   return tmpout;
                   1905: }
1.213     brouard  1906:  
                   1907: /*************** function subdirfext ***********/
                   1908: char *subdirfext(char fileres[], char *preop, char *postop)
                   1909: {
                   1910:   
                   1911:   strcpy(tmpout,preop);
                   1912:   strcat(tmpout,fileres);
                   1913:   strcat(tmpout,postop);
                   1914:   return tmpout;
                   1915: }
1.126     brouard  1916: 
1.213     brouard  1917: /*************** function subdirfext3 ***********/
                   1918: char *subdirfext3(char fileres[], char *preop, char *postop)
                   1919: {
                   1920:   
                   1921:   /* Caution optionfilefiname is hidden */
                   1922:   strcpy(tmpout,optionfilefiname);
                   1923:   strcat(tmpout,"/");
                   1924:   strcat(tmpout,preop);
                   1925:   strcat(tmpout,fileres);
                   1926:   strcat(tmpout,postop);
                   1927:   return tmpout;
                   1928: }
                   1929:  
1.162     brouard  1930: char *asc_diff_time(long time_sec, char ascdiff[])
                   1931: {
                   1932:   long sec_left, days, hours, minutes;
                   1933:   days = (time_sec) / (60*60*24);
                   1934:   sec_left = (time_sec) % (60*60*24);
                   1935:   hours = (sec_left) / (60*60) ;
                   1936:   sec_left = (sec_left) %(60*60);
                   1937:   minutes = (sec_left) /60;
                   1938:   sec_left = (sec_left) % (60);
                   1939:   sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
                   1940:   return ascdiff;
                   1941: }
                   1942: 
1.126     brouard  1943: /***************** f1dim *************************/
                   1944: extern int ncom; 
                   1945: extern double *pcom,*xicom;
                   1946: extern double (*nrfunc)(double []); 
                   1947:  
                   1948: double f1dim(double x) 
                   1949: { 
                   1950:   int j; 
                   1951:   double f;
                   1952:   double *xt; 
                   1953:  
                   1954:   xt=vector(1,ncom); 
                   1955:   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
                   1956:   f=(*nrfunc)(xt); 
                   1957:   free_vector(xt,1,ncom); 
                   1958:   return f; 
                   1959: } 
                   1960: 
                   1961: /*****************brent *************************/
                   1962: double brent(double ax, double bx, double cx, double (*f)(double), double tol,         double *xmin) 
1.187     brouard  1963: {
                   1964:   /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
                   1965:    * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
                   1966:    * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
                   1967:    * the minimum is returned as xmin, and the minimum function value is returned as brent , the
                   1968:    * returned function value. 
                   1969:   */
1.126     brouard  1970:   int iter; 
                   1971:   double a,b,d,etemp;
1.159     brouard  1972:   double fu=0,fv,fw,fx;
1.164     brouard  1973:   double ftemp=0.;
1.126     brouard  1974:   double p,q,r,tol1,tol2,u,v,w,x,xm; 
                   1975:   double e=0.0; 
                   1976:  
                   1977:   a=(ax < cx ? ax : cx); 
                   1978:   b=(ax > cx ? ax : cx); 
                   1979:   x=w=v=bx; 
                   1980:   fw=fv=fx=(*f)(x); 
                   1981:   for (iter=1;iter<=ITMAX;iter++) { 
                   1982:     xm=0.5*(a+b); 
                   1983:     tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
                   1984:     /*         if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
                   1985:     printf(".");fflush(stdout);
                   1986:     fprintf(ficlog,".");fflush(ficlog);
1.162     brouard  1987: #ifdef DEBUGBRENT
1.126     brouard  1988:     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1989:     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                   1990:     /*         if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   1991: #endif
                   1992:     if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   1993:       *xmin=x; 
                   1994:       return fx; 
                   1995:     } 
                   1996:     ftemp=fu;
                   1997:     if (fabs(e) > tol1) { 
                   1998:       r=(x-w)*(fx-fv); 
                   1999:       q=(x-v)*(fx-fw); 
                   2000:       p=(x-v)*q-(x-w)*r; 
                   2001:       q=2.0*(q-r); 
                   2002:       if (q > 0.0) p = -p; 
                   2003:       q=fabs(q); 
                   2004:       etemp=e; 
                   2005:       e=d; 
                   2006:       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
1.224     brouard  2007:                                d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
1.126     brouard  2008:       else { 
1.224     brouard  2009:                                d=p/q; 
                   2010:                                u=x+d; 
                   2011:                                if (u-a < tol2 || b-u < tol2) 
                   2012:                                        d=SIGN(tol1,xm-x); 
1.126     brouard  2013:       } 
                   2014:     } else { 
                   2015:       d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
                   2016:     } 
                   2017:     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
                   2018:     fu=(*f)(u); 
                   2019:     if (fu <= fx) { 
                   2020:       if (u >= x) a=x; else b=x; 
                   2021:       SHFT(v,w,x,u) 
1.183     brouard  2022:       SHFT(fv,fw,fx,fu) 
                   2023:     } else { 
                   2024:       if (u < x) a=u; else b=u; 
                   2025:       if (fu <= fw || w == x) { 
1.224     brouard  2026:                                v=w; 
                   2027:                                w=u; 
                   2028:                                fv=fw; 
                   2029:                                fw=fu; 
1.183     brouard  2030:       } else if (fu <= fv || v == x || v == w) { 
1.224     brouard  2031:                                v=u; 
                   2032:                                fv=fu; 
1.183     brouard  2033:       } 
                   2034:     } 
1.126     brouard  2035:   } 
                   2036:   nrerror("Too many iterations in brent"); 
                   2037:   *xmin=x; 
                   2038:   return fx; 
                   2039: } 
                   2040: 
                   2041: /****************** mnbrak ***********************/
                   2042: 
                   2043: void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
                   2044:            double (*func)(double)) 
1.183     brouard  2045: { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
                   2046: the downhill direction (defined by the function as evaluated at the initial points) and returns
                   2047: new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
                   2048: values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
                   2049:    */
1.126     brouard  2050:   double ulim,u,r,q, dum;
                   2051:   double fu; 
1.187     brouard  2052: 
                   2053:   double scale=10.;
                   2054:   int iterscale=0;
                   2055: 
                   2056:   *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
                   2057:   *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
                   2058: 
                   2059: 
                   2060:   /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
                   2061:   /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
                   2062:   /*   *bx = *ax - (*ax - *bx)/scale; */
                   2063:   /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
                   2064:   /* } */
                   2065: 
1.126     brouard  2066:   if (*fb > *fa) { 
                   2067:     SHFT(dum,*ax,*bx,dum) 
1.183     brouard  2068:     SHFT(dum,*fb,*fa,dum) 
                   2069:   } 
1.126     brouard  2070:   *cx=(*bx)+GOLD*(*bx-*ax); 
                   2071:   *fc=(*func)(*cx); 
1.183     brouard  2072: #ifdef DEBUG
1.224     brouard  2073:   printf("mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
                   2074:   fprintf(ficlog,"mnbrak0 a=%lf *fa=%lf, b=%lf *fb=%lf, c=%lf *fc=%lf\n",*ax,*fa,*bx,*fb,*cx, *fc);
1.183     brouard  2075: #endif
1.224     brouard  2076:   while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc. If fc=inf it exits and if flat fb=fc it exits too.*/
1.126     brouard  2077:     r=(*bx-*ax)*(*fb-*fc); 
1.224     brouard  2078:     q=(*bx-*cx)*(*fb-*fa); /* What if fa=inf */
1.126     brouard  2079:     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
1.183     brouard  2080:       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
                   2081:     ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
                   2082:     if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
1.126     brouard  2083:       fu=(*func)(u); 
1.163     brouard  2084: #ifdef DEBUG
                   2085:       /* f(x)=A(x-u)**2+f(u) */
                   2086:       double A, fparabu; 
                   2087:       A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2088:       fparabu= *fa - A*(*ax-u)*(*ax-u);
1.224     brouard  2089:       printf("\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
                   2090:       fprintf(ficlog,"\nmnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f, q=%lf < %lf=r)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu,q,r);
1.183     brouard  2091:       /* And thus,it can be that fu > *fc even if fparabu < *fc */
                   2092:       /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
                   2093:         (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
                   2094:       /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
1.163     brouard  2095: #endif 
1.184     brouard  2096: #ifdef MNBRAKORIGINAL
1.183     brouard  2097: #else
1.191     brouard  2098: /*       if (fu > *fc) { */
                   2099: /* #ifdef DEBUG */
                   2100: /*       printf("mnbrak4  fu > fc \n"); */
                   2101: /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
                   2102: /* #endif */
                   2103: /*     /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
                   2104: /*     /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
                   2105: /*     dum=u; /\* Shifting c and u *\/ */
                   2106: /*     u = *cx; */
                   2107: /*     *cx = dum; */
                   2108: /*     dum = fu; */
                   2109: /*     fu = *fc; */
                   2110: /*     *fc =dum; */
                   2111: /*       } else { /\* end *\/ */
                   2112: /* #ifdef DEBUG */
                   2113: /*       printf("mnbrak3  fu < fc \n"); */
                   2114: /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
                   2115: /* #endif */
                   2116: /*     dum=u; /\* Shifting c and u *\/ */
                   2117: /*     u = *cx; */
                   2118: /*     *cx = dum; */
                   2119: /*     dum = fu; */
                   2120: /*     fu = *fc; */
                   2121: /*     *fc =dum; */
                   2122: /*       } */
1.224     brouard  2123: #ifdef DEBUGMNBRAK
                   2124:                 double A, fparabu; 
                   2125:      A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
                   2126:      fparabu= *fa - A*(*ax-u)*(*ax-u);
                   2127:      printf("\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
                   2128:      fprintf(ficlog,"\nmnbrak35 ax=%lf fa=%lf bx=%lf fb=%lf, u=%lf fp=%lf fu=%lf < or >= fc=%lf cx=%lf, q=%lf < %lf=r \n",*ax, *fa, *bx,*fb,u,fparabu,fu,*fc,*cx,q,r);
1.183     brouard  2129: #endif
1.191     brouard  2130:       dum=u; /* Shifting c and u */
                   2131:       u = *cx;
                   2132:       *cx = dum;
                   2133:       dum = fu;
                   2134:       fu = *fc;
                   2135:       *fc =dum;
1.183     brouard  2136: #endif
1.162     brouard  2137:     } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
1.183     brouard  2138: #ifdef DEBUG
1.224     brouard  2139:       printf("\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
                   2140:       fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim\n",u,*cx);
1.183     brouard  2141: #endif
1.126     brouard  2142:       fu=(*func)(u); 
                   2143:       if (fu < *fc) { 
1.183     brouard  2144: #ifdef DEBUG
1.224     brouard  2145:                                printf("\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2146:                          fprintf(ficlog,"\nmnbrak2  u=%lf after c=%lf but before ulim=%lf AND fu=%lf < %lf=fc\n",u,*cx,ulim,fu, *fc);
                   2147: #endif
                   2148:                          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
                   2149:                                SHFT(*fb,*fc,fu,(*func)(u)) 
                   2150: #ifdef DEBUG
                   2151:                                        printf("\nmnbrak2 shift GOLD c=%lf",*cx+GOLD*(*cx-*bx));
1.183     brouard  2152: #endif
                   2153:       } 
1.162     brouard  2154:     } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
1.183     brouard  2155: #ifdef DEBUG
1.224     brouard  2156:       printf("\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
                   2157:       fprintf(ficlog,"\nmnbrak2  u=%lf outside ulim=%lf (verifying that ulim is beyond c=%lf)\n",u,ulim,*cx);
1.183     brouard  2158: #endif
1.126     brouard  2159:       u=ulim; 
                   2160:       fu=(*func)(u); 
1.183     brouard  2161:     } else { /* u could be left to b (if r > q parabola has a maximum) */
                   2162: #ifdef DEBUG
1.224     brouard  2163:       printf("\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
                   2164:       fprintf(ficlog,"\nmnbrak2  u=%lf could be left to b=%lf (if r=%lf > q=%lf parabola has a maximum)\n",u,*bx,r,q);
1.183     brouard  2165: #endif
1.126     brouard  2166:       u=(*cx)+GOLD*(*cx-*bx); 
                   2167:       fu=(*func)(u); 
1.224     brouard  2168: #ifdef DEBUG
                   2169:       printf("\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2170:       fprintf(ficlog,"\nmnbrak2 new u=%lf fu=%lf shifted gold left from c=%lf and b=%lf \n",u,fu,*cx,*bx);
                   2171: #endif
1.183     brouard  2172:     } /* end tests */
1.126     brouard  2173:     SHFT(*ax,*bx,*cx,u) 
1.183     brouard  2174:     SHFT(*fa,*fb,*fc,fu) 
                   2175: #ifdef DEBUG
1.224     brouard  2176:       printf("\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
                   2177:       fprintf(ficlog, "\nmnbrak2 shift (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc);
1.183     brouard  2178: #endif
                   2179:   } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
1.126     brouard  2180: } 
                   2181: 
                   2182: /*************** linmin ************************/
1.162     brouard  2183: /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
                   2184: resets p to where the function func(p) takes on a minimum along the direction xi from p ,
                   2185: and replaces xi by the actual vector displacement that p was moved. Also returns as fret
                   2186: the value of func at the returned location p . This is actually all accomplished by calling the
                   2187: routines mnbrak and brent .*/
1.126     brouard  2188: int ncom; 
                   2189: double *pcom,*xicom;
                   2190: double (*nrfunc)(double []); 
                   2191:  
1.224     brouard  2192: #ifdef LINMINORIGINAL
1.126     brouard  2193: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
1.224     brouard  2194: #else
                   2195: void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []), int *flat) 
                   2196: #endif
1.126     brouard  2197: { 
                   2198:   double brent(double ax, double bx, double cx, 
                   2199:               double (*f)(double), double tol, double *xmin); 
                   2200:   double f1dim(double x); 
                   2201:   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
                   2202:              double *fc, double (*func)(double)); 
                   2203:   int j; 
                   2204:   double xx,xmin,bx,ax; 
                   2205:   double fx,fb,fa;
1.187     brouard  2206: 
1.203     brouard  2207: #ifdef LINMINORIGINAL
                   2208: #else
                   2209:   double scale=10., axs, xxs; /* Scale added for infinity */
                   2210: #endif
                   2211:   
1.126     brouard  2212:   ncom=n; 
                   2213:   pcom=vector(1,n); 
                   2214:   xicom=vector(1,n); 
                   2215:   nrfunc=func; 
                   2216:   for (j=1;j<=n;j++) { 
                   2217:     pcom[j]=p[j]; 
1.202     brouard  2218:     xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
1.126     brouard  2219:   } 
1.187     brouard  2220: 
1.203     brouard  2221: #ifdef LINMINORIGINAL
                   2222:   xx=1.;
                   2223: #else
                   2224:   axs=0.0;
                   2225:   xxs=1.;
                   2226:   do{
                   2227:     xx= xxs;
                   2228: #endif
1.187     brouard  2229:     ax=0.;
                   2230:     mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
                   2231:     /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
                   2232:     /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
                   2233:     /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
                   2234:     /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
                   2235:     /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
                   2236:     /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
1.203     brouard  2237: #ifdef LINMINORIGINAL
                   2238: #else
                   2239:     if (fx != fx){
1.224     brouard  2240:                        xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
                   2241:                        printf("|");
                   2242:                        fprintf(ficlog,"|");
1.203     brouard  2243: #ifdef DEBUGLINMIN
1.224     brouard  2244:                        printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
1.203     brouard  2245: #endif
                   2246:     }
1.224     brouard  2247:   }while(fx != fx && xxs > 1.e-5);
1.203     brouard  2248: #endif
                   2249:   
1.191     brouard  2250: #ifdef DEBUGLINMIN
                   2251:   printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.202     brouard  2252:   fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
1.191     brouard  2253: #endif
1.224     brouard  2254: #ifdef LINMINORIGINAL
                   2255: #else
                   2256:        if(fb == fx){ /* Flat function in the direction */
                   2257:                xmin=xx;
                   2258:     *flat=1;
                   2259:        }else{
                   2260:     *flat=0;
                   2261: #endif
                   2262:                /*Flat mnbrak2 shift (*ax=0.000000000000, *fa=51626.272983130431), (*bx=-1.618034000000, *fb=51590.149499362531), (*cx=-4.236068025156, *fc=51590.149499362531) */
1.187     brouard  2263:   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
                   2264:   /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
                   2265:   /* fmin = f(p[j] + xmin * xi[j]) */
                   2266:   /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
                   2267:   /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
1.126     brouard  2268: #ifdef DEBUG
1.224     brouard  2269:   printf("retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2270:   fprintf(ficlog,"retour brent from bracket (a=%lf fa=%lf, xx=%lf fx=%lf, b=%lf fb=%lf): fret=%lf xmin=%lf\n",ax,fa,xx,fx,bx,fb,*fret,xmin);
                   2271: #endif
                   2272: #ifdef LINMINORIGINAL
                   2273: #else
                   2274:                        }
1.126     brouard  2275: #endif
1.191     brouard  2276: #ifdef DEBUGLINMIN
                   2277:   printf("linmin end ");
1.202     brouard  2278:   fprintf(ficlog,"linmin end ");
1.191     brouard  2279: #endif
1.126     brouard  2280:   for (j=1;j<=n;j++) { 
1.203     brouard  2281: #ifdef LINMINORIGINAL
                   2282:     xi[j] *= xmin; 
                   2283: #else
                   2284: #ifdef DEBUGLINMIN
                   2285:     if(xxs <1.0)
                   2286:       printf(" before xi[%d]=%12.8f", j,xi[j]);
                   2287: #endif
                   2288:     xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
                   2289: #ifdef DEBUGLINMIN
                   2290:     if(xxs <1.0)
                   2291:       printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
                   2292: #endif
                   2293: #endif
1.187     brouard  2294:     p[j] += xi[j]; /* Parameters values are updated accordingly */
1.126     brouard  2295:   } 
1.191     brouard  2296: #ifdef DEBUGLINMIN
1.203     brouard  2297:   printf("\n");
1.191     brouard  2298:   printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.202     brouard  2299:   fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
1.191     brouard  2300:   for (j=1;j<=n;j++) { 
1.202     brouard  2301:     printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2302:     fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
                   2303:     if(j % ncovmodel == 0){
1.191     brouard  2304:       printf("\n");
1.202     brouard  2305:       fprintf(ficlog,"\n");
                   2306:     }
1.191     brouard  2307:   }
1.203     brouard  2308: #else
1.191     brouard  2309: #endif
1.126     brouard  2310:   free_vector(xicom,1,n); 
                   2311:   free_vector(pcom,1,n); 
                   2312: } 
                   2313: 
                   2314: 
                   2315: /*************** powell ************************/
1.162     brouard  2316: /*
                   2317: Minimization of a function func of n variables. Input consists of an initial starting point
                   2318: p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
                   2319: rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
                   2320: such that failure to decrease by more than this amount on one iteration signals doneness. On
                   2321: output, p is set to the best point found, xi is the then-current direction set, fret is the returned
                   2322: function value at p , and iter is the number of iterations taken. The routine linmin is used.
                   2323:  */
1.224     brouard  2324: #ifdef LINMINORIGINAL
                   2325: #else
                   2326:        int *flatdir; /* Function is vanishing in that direction */
1.225     brouard  2327:        int flat=0, flatd=0; /* Function is vanishing in that direction */
1.224     brouard  2328: #endif
1.126     brouard  2329: void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
                   2330:            double (*func)(double [])) 
                   2331: { 
1.224     brouard  2332: #ifdef LINMINORIGINAL
                   2333:  void linmin(double p[], double xi[], int n, double *fret, 
1.126     brouard  2334:              double (*func)(double [])); 
1.224     brouard  2335: #else 
1.241     brouard  2336:  void linmin(double p[], double xi[], int n, double *fret,
                   2337:             double (*func)(double []),int *flat); 
1.224     brouard  2338: #endif
1.239     brouard  2339:  int i,ibig,j,jk,k; 
1.126     brouard  2340:   double del,t,*pt,*ptt,*xit;
1.181     brouard  2341:   double directest;
1.126     brouard  2342:   double fp,fptt;
                   2343:   double *xits;
                   2344:   int niterf, itmp;
1.224     brouard  2345: #ifdef LINMINORIGINAL
                   2346: #else
                   2347: 
                   2348:   flatdir=ivector(1,n); 
                   2349:   for (j=1;j<=n;j++) flatdir[j]=0; 
                   2350: #endif
1.126     brouard  2351: 
                   2352:   pt=vector(1,n); 
                   2353:   ptt=vector(1,n); 
                   2354:   xit=vector(1,n); 
                   2355:   xits=vector(1,n); 
                   2356:   *fret=(*func)(p); 
                   2357:   for (j=1;j<=n;j++) pt[j]=p[j]; 
1.202     brouard  2358:   rcurr_time = time(NULL);  
1.126     brouard  2359:   for (*iter=1;;++(*iter)) { 
1.187     brouard  2360:     fp=(*fret); /* From former iteration or initial value */
1.126     brouard  2361:     ibig=0; 
                   2362:     del=0.0; 
1.157     brouard  2363:     rlast_time=rcurr_time;
                   2364:     /* (void) gettimeofday(&curr_time,&tzp); */
                   2365:     rcurr_time = time(NULL);  
                   2366:     curr_time = *localtime(&rcurr_time);
                   2367:     printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
                   2368:     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
                   2369: /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
1.192     brouard  2370:     for (i=1;i<=n;i++) {
1.126     brouard  2371:       fprintf(ficrespow," %.12lf", p[i]);
                   2372:     }
1.239     brouard  2373:     fprintf(ficrespow,"\n");fflush(ficrespow);
                   2374:     printf("\n#model=  1      +     age ");
                   2375:     fprintf(ficlog,"\n#model=  1      +     age ");
                   2376:     if(nagesqr==1){
1.241     brouard  2377:        printf("  + age*age  ");
                   2378:        fprintf(ficlog,"  + age*age  ");
1.239     brouard  2379:     }
                   2380:     for(j=1;j <=ncovmodel-2;j++){
                   2381:       if(Typevar[j]==0) {
                   2382:        printf("  +      V%d  ",Tvar[j]);
                   2383:        fprintf(ficlog,"  +      V%d  ",Tvar[j]);
                   2384:       }else if(Typevar[j]==1) {
                   2385:        printf("  +    V%d*age ",Tvar[j]);
                   2386:        fprintf(ficlog,"  +    V%d*age ",Tvar[j]);
                   2387:       }else if(Typevar[j]==2) {
                   2388:        printf("  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2389:        fprintf(ficlog,"  +    V%d*V%d ",Tvard[Tposprod[j]][1],Tvard[Tposprod[j]][2]);
                   2390:       }
                   2391:     }
1.126     brouard  2392:     printf("\n");
1.239     brouard  2393: /*     printf("12   47.0114589    0.0154322   33.2424412    0.3279905    2.3731903  */
                   2394: /* 13  -21.5392400    0.1118147    1.2680506    1.2973408   -1.0663662  */
1.126     brouard  2395:     fprintf(ficlog,"\n");
1.239     brouard  2396:     for(i=1,jk=1; i <=nlstate; i++){
                   2397:       for(k=1; k <=(nlstate+ndeath); k++){
                   2398:        if (k != i) {
                   2399:          printf("%d%d ",i,k);
                   2400:          fprintf(ficlog,"%d%d ",i,k);
                   2401:          for(j=1; j <=ncovmodel; j++){
                   2402:            printf("%12.7f ",p[jk]);
                   2403:            fprintf(ficlog,"%12.7f ",p[jk]);
                   2404:            jk++; 
                   2405:          }
                   2406:          printf("\n");
                   2407:          fprintf(ficlog,"\n");
                   2408:        }
                   2409:       }
                   2410:     }
1.241     brouard  2411:     if(*iter <=3 && *iter >1){
1.157     brouard  2412:       tml = *localtime(&rcurr_time);
                   2413:       strcpy(strcurr,asctime(&tml));
                   2414:       rforecast_time=rcurr_time; 
1.126     brouard  2415:       itmp = strlen(strcurr);
                   2416:       if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
1.241     brouard  2417:        strcurr[itmp-1]='\0';
1.162     brouard  2418:       printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.157     brouard  2419:       fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
1.126     brouard  2420:       for(niterf=10;niterf<=30;niterf+=10){
1.241     brouard  2421:        rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
                   2422:        forecast_time = *localtime(&rforecast_time);
                   2423:        strcpy(strfor,asctime(&forecast_time));
                   2424:        itmp = strlen(strfor);
                   2425:        if(strfor[itmp-1]=='\n')
                   2426:          strfor[itmp-1]='\0';
                   2427:        printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
                   2428:        fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
1.126     brouard  2429:       }
                   2430:     }
1.187     brouard  2431:     for (i=1;i<=n;i++) { /* For each direction i */
                   2432:       for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
1.126     brouard  2433:       fptt=(*fret); 
                   2434: #ifdef DEBUG
1.203     brouard  2435:       printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
                   2436:       fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
1.126     brouard  2437: #endif
1.203     brouard  2438:       printf("%d",i);fflush(stdout); /* print direction (parameter) i */
1.126     brouard  2439:       fprintf(ficlog,"%d",i);fflush(ficlog);
1.224     brouard  2440: #ifdef LINMINORIGINAL
1.188     brouard  2441:       linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
1.224     brouard  2442: #else
                   2443:       linmin(p,xit,n,fret,func,&flat); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
                   2444:                        flatdir[i]=flat; /* Function is vanishing in that direction i */
                   2445: #endif
                   2446:                        /* Outputs are fret(new point p) p is updated and xit rescaled */
1.188     brouard  2447:       if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
1.224     brouard  2448:                                /* because that direction will be replaced unless the gain del is small */
                   2449:                                /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
                   2450:                                /* Unless the n directions are conjugate some gain in the determinant may be obtained */
                   2451:                                /* with the new direction. */
                   2452:                                del=fabs(fptt-(*fret)); 
                   2453:                                ibig=i; 
1.126     brouard  2454:       } 
                   2455: #ifdef DEBUG
                   2456:       printf("%d %.12e",i,(*fret));
                   2457:       fprintf(ficlog,"%d %.12e",i,(*fret));
                   2458:       for (j=1;j<=n;j++) {
1.224     brouard  2459:                                xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
                   2460:                                printf(" x(%d)=%.12e",j,xit[j]);
                   2461:                                fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
1.126     brouard  2462:       }
                   2463:       for(j=1;j<=n;j++) {
1.225     brouard  2464:                                printf(" p(%d)=%.12e",j,p[j]);
                   2465:                                fprintf(ficlog," p(%d)=%.12e",j,p[j]);
1.126     brouard  2466:       }
                   2467:       printf("\n");
                   2468:       fprintf(ficlog,"\n");
                   2469: #endif
1.187     brouard  2470:     } /* end loop on each direction i */
                   2471:     /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
1.188     brouard  2472:     /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
1.187     brouard  2473:     /* New value of last point Pn is not computed, P(n-1) */
1.224     brouard  2474:       for(j=1;j<=n;j++) {
1.302     brouard  2475:        if(flatdir[j] >0){
                   2476:          printf(" p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2477:          fprintf(ficlog," p(%d)=%lf flat=%d ",j,p[j],flatdir[j]);
                   2478:        }
                   2479:        /* printf("\n"); */
                   2480:        /* fprintf(ficlog,"\n"); */
                   2481:       }
1.243     brouard  2482:     /* if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /\* Did we reach enough precision? *\/ */
                   2483:     if (2.0*fabs(fp-(*fret)) <= ftol) { /* Did we reach enough precision? */
1.188     brouard  2484:       /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
                   2485:       /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
                   2486:       /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
                   2487:       /* decreased of more than 3.84  */
                   2488:       /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
                   2489:       /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
                   2490:       /* By adding 10 parameters more the gain should be 18.31 */
1.224     brouard  2491:                        
1.188     brouard  2492:       /* Starting the program with initial values given by a former maximization will simply change */
                   2493:       /* the scales of the directions and the directions, because the are reset to canonical directions */
                   2494:       /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
                   2495:       /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
1.126     brouard  2496: #ifdef DEBUG
                   2497:       int k[2],l;
                   2498:       k[0]=1;
                   2499:       k[1]=-1;
                   2500:       printf("Max: %.12e",(*func)(p));
                   2501:       fprintf(ficlog,"Max: %.12e",(*func)(p));
                   2502:       for (j=1;j<=n;j++) {
                   2503:        printf(" %.12e",p[j]);
                   2504:        fprintf(ficlog," %.12e",p[j]);
                   2505:       }
                   2506:       printf("\n");
                   2507:       fprintf(ficlog,"\n");
                   2508:       for(l=0;l<=1;l++) {
                   2509:        for (j=1;j<=n;j++) {
                   2510:          ptt[j]=p[j]+(p[j]-pt[j])*k[l];
                   2511:          printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2512:          fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
                   2513:        }
                   2514:        printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2515:        fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
                   2516:       }
                   2517: #endif
                   2518: 
1.224     brouard  2519: #ifdef LINMINORIGINAL
                   2520: #else
                   2521:       free_ivector(flatdir,1,n); 
                   2522: #endif
1.126     brouard  2523:       free_vector(xit,1,n); 
                   2524:       free_vector(xits,1,n); 
                   2525:       free_vector(ptt,1,n); 
                   2526:       free_vector(pt,1,n); 
                   2527:       return; 
1.192     brouard  2528:     } /* enough precision */ 
1.240     brouard  2529:     if (*iter == ITMAX*n) nrerror("powell exceeding maximum iterations."); 
1.181     brouard  2530:     for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
1.126     brouard  2531:       ptt[j]=2.0*p[j]-pt[j]; 
                   2532:       xit[j]=p[j]-pt[j]; 
                   2533:       pt[j]=p[j]; 
                   2534:     } 
1.181     brouard  2535:     fptt=(*func)(ptt); /* f_3 */
1.224     brouard  2536: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
                   2537:                if (*iter <=4) {
1.225     brouard  2538: #else
                   2539: #endif
1.224     brouard  2540: #ifdef POWELLNOF3INFF1TEST    /* skips test F3 <F1 */
1.192     brouard  2541: #else
1.161     brouard  2542:     if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
1.192     brouard  2543: #endif
1.162     brouard  2544:       /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
1.161     brouard  2545:       /* From x1 (P0) distance of x2 is at h and x3 is 2h */
1.162     brouard  2546:       /* Let f"(x2) be the 2nd derivative equal everywhere.  */
                   2547:       /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
                   2548:       /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
1.224     brouard  2549:       /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del or directest <0 */
                   2550:       /* also  lamda^2=(f1-f2)^2/mu² is a parasite solution of powell */
                   2551:       /* For powell, inclusion of this average direction is only if t(del)<0 or del inbetween mu^2 and lambda^2 */
1.161     brouard  2552:       /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
1.224     brouard  2553:       /*  Even if f3 <f1, directest can be negative and t >0 */
                   2554:       /* mu² and del² are equal when f3=f1 */
                   2555:                        /* f3 < f1 : mu² < del <= lambda^2 both test are equivalent */
                   2556:                        /* f3 < f1 : mu² < lambda^2 < del then directtest is negative and powell t is positive */
                   2557:                        /* f3 > f1 : lambda² < mu^2 < del then t is negative and directest >0  */
                   2558:                        /* f3 > f1 : lambda² < del < mu^2 then t is positive and directest >0  */
1.183     brouard  2559: #ifdef NRCORIGINAL
                   2560:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
                   2561: #else
                   2562:       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
1.161     brouard  2563:       t= t- del*SQR(fp-fptt);
1.183     brouard  2564: #endif
1.202     brouard  2565:       directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
1.161     brouard  2566: #ifdef DEBUG
1.181     brouard  2567:       printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
                   2568:       fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
1.161     brouard  2569:       printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2570:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2571:       fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
                   2572:             (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
                   2573:       printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2574:       fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
                   2575: #endif
1.183     brouard  2576: #ifdef POWELLORIGINAL
                   2577:       if (t < 0.0) { /* Then we use it for new direction */
                   2578: #else
1.182     brouard  2579:       if (directest*t < 0.0) { /* Contradiction between both tests */
1.224     brouard  2580:                                printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
1.192     brouard  2581:         printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
1.224     brouard  2582:         fprintf(ficlog,"directest= %.12lf (if directest<0 or t<0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
1.192     brouard  2583:         fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
                   2584:       } 
1.181     brouard  2585:       if (directest < 0.0) { /* Then we use it for new direction */
                   2586: #endif
1.191     brouard  2587: #ifdef DEBUGLINMIN
1.234     brouard  2588:        printf("Before linmin in direction P%d-P0\n",n);
                   2589:        for (j=1;j<=n;j++) {
                   2590:          printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2591:          fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2592:          if(j % ncovmodel == 0){
                   2593:            printf("\n");
                   2594:            fprintf(ficlog,"\n");
                   2595:          }
                   2596:        }
1.224     brouard  2597: #endif
                   2598: #ifdef LINMINORIGINAL
1.234     brouard  2599:        linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
1.224     brouard  2600: #else
1.234     brouard  2601:        linmin(p,xit,n,fret,func,&flat); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
                   2602:        flatdir[i]=flat; /* Function is vanishing in that direction i */
1.191     brouard  2603: #endif
1.234     brouard  2604:        
1.191     brouard  2605: #ifdef DEBUGLINMIN
1.234     brouard  2606:        for (j=1;j<=n;j++) { 
                   2607:          printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2608:          fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
                   2609:          if(j % ncovmodel == 0){
                   2610:            printf("\n");
                   2611:            fprintf(ficlog,"\n");
                   2612:          }
                   2613:        }
1.224     brouard  2614: #endif
1.234     brouard  2615:        for (j=1;j<=n;j++) { 
                   2616:          xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
                   2617:          xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
                   2618:        }
1.224     brouard  2619: #ifdef LINMINORIGINAL
                   2620: #else
1.234     brouard  2621:        for (j=1, flatd=0;j<=n;j++) {
                   2622:          if(flatdir[j]>0)
                   2623:            flatd++;
                   2624:        }
                   2625:        if(flatd >0){
1.255     brouard  2626:          printf("%d flat directions: ",flatd);
                   2627:          fprintf(ficlog,"%d flat directions :",flatd);
1.234     brouard  2628:          for (j=1;j<=n;j++) { 
                   2629:            if(flatdir[j]>0){
                   2630:              printf("%d ",j);
                   2631:              fprintf(ficlog,"%d ",j);
                   2632:            }
                   2633:          }
                   2634:          printf("\n");
                   2635:          fprintf(ficlog,"\n");
                   2636:        }
1.191     brouard  2637: #endif
1.234     brouard  2638:        printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2639:        fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
                   2640:        
1.126     brouard  2641: #ifdef DEBUG
1.234     brouard  2642:        printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2643:        fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
                   2644:        for(j=1;j<=n;j++){
                   2645:          printf(" %lf",xit[j]);
                   2646:          fprintf(ficlog," %lf",xit[j]);
                   2647:        }
                   2648:        printf("\n");
                   2649:        fprintf(ficlog,"\n");
1.126     brouard  2650: #endif
1.192     brouard  2651:       } /* end of t or directest negative */
1.224     brouard  2652: #ifdef POWELLNOF3INFF1TEST
1.192     brouard  2653: #else
1.234     brouard  2654:       } /* end if (fptt < fp)  */
1.192     brouard  2655: #endif
1.225     brouard  2656: #ifdef NODIRECTIONCHANGEDUNTILNITER  /* No change in drections until some iterations are done */
1.234     brouard  2657:     } /*NODIRECTIONCHANGEDUNTILNITER  No change in drections until some iterations are done */
1.225     brouard  2658: #else
1.224     brouard  2659: #endif
1.234     brouard  2660:                } /* loop iteration */ 
1.126     brouard  2661: } 
1.234     brouard  2662:   
1.126     brouard  2663: /**** Prevalence limit (stable or period prevalence)  ****************/
1.234     brouard  2664:   
1.235     brouard  2665:   double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij, int nres)
1.234     brouard  2666:   {
1.279     brouard  2667:     /**< Computes the prevalence limit in each live state at age x and for covariate combination ij 
                   2668:      *   (and selected quantitative values in nres)
                   2669:      *  by left multiplying the unit
                   2670:      *  matrix by transitions matrix until convergence is reached with precision ftolpl 
                   2671:      * Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I
                   2672:      * Wx is row vector: population in state 1, population in state 2, population dead
                   2673:      * or prevalence in state 1, prevalence in state 2, 0
                   2674:      * newm is the matrix after multiplications, its rows are identical at a factor.
                   2675:      * Inputs are the parameter, age, a tolerance for the prevalence limit ftolpl.
                   2676:      * Output is prlim.
                   2677:      * Initial matrix pimij 
                   2678:      */
1.206     brouard  2679:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2680:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2681:   /*  0,                   0                  , 1} */
                   2682:   /*
                   2683:    * and after some iteration: */
                   2684:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2685:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2686:   /*  0,                   0                  , 1} */
                   2687:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2688:   /* {0.51571254859325999, 0.4842874514067399, */
                   2689:   /*  0.51326036147820708, 0.48673963852179264} */
                   2690:   /* If we start from prlim again, prlim tends to a constant matrix */
1.234     brouard  2691:     
1.126     brouard  2692:   int i, ii,j,k;
1.209     brouard  2693:   double *min, *max, *meandiff, maxmax,sumnew=0.;
1.145     brouard  2694:   /* double **matprod2(); */ /* test */
1.218     brouard  2695:   double **out, cov[NCOVMAX+1], **pmij(); /* **pmmij is a global variable feeded with oldms etc */
1.126     brouard  2696:   double **newm;
1.209     brouard  2697:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
1.203     brouard  2698:   int ncvloop=0;
1.288     brouard  2699:   int first=0;
1.169     brouard  2700:   
1.209     brouard  2701:   min=vector(1,nlstate);
                   2702:   max=vector(1,nlstate);
                   2703:   meandiff=vector(1,nlstate);
                   2704: 
1.218     brouard  2705:        /* Starting with matrix unity */
1.126     brouard  2706:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2707:     for (j=1;j<=nlstate+ndeath;j++){
                   2708:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2709:     }
1.169     brouard  2710:   
                   2711:   cov[1]=1.;
                   2712:   
                   2713:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
1.202     brouard  2714:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.126     brouard  2715:   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
1.202     brouard  2716:     ncvloop++;
1.126     brouard  2717:     newm=savm;
                   2718:     /* Covariates have to be included here again */
1.138     brouard  2719:     cov[2]=agefin;
1.187     brouard  2720:     if(nagesqr==1)
                   2721:       cov[3]= agefin*agefin;;
1.234     brouard  2722:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2723:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2724:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.235     brouard  2725:       /* printf("prevalim Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.234     brouard  2726:     }
                   2727:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2728:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
1.235     brouard  2729:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2730:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
1.138     brouard  2731:     }
1.237     brouard  2732:     for (k=1; k<=cptcovage;k++){  /* For product with age */
1.234     brouard  2733:       if(Dummy[Tvar[Tage[k]]]){
                   2734:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2735:       } else{
1.235     brouard  2736:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
1.234     brouard  2737:       }
1.235     brouard  2738:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
1.234     brouard  2739:     }
1.237     brouard  2740:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
1.235     brouard  2741:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
1.237     brouard  2742:       if(Dummy[Tvard[k][1]==0]){
                   2743:        if(Dummy[Tvard[k][2]==0]){
                   2744:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2745:        }else{
                   2746:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2747:        }
                   2748:       }else{
                   2749:        if(Dummy[Tvard[k][2]==0]){
                   2750:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2751:        }else{
                   2752:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2753:        }
                   2754:       }
1.234     brouard  2755:     }
1.138     brouard  2756:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2757:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2758:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
1.145     brouard  2759:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2760:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2761:                /* age and covariate values of ij are in 'cov' */
1.142     brouard  2762:     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
1.138     brouard  2763:     
1.126     brouard  2764:     savm=oldm;
                   2765:     oldm=newm;
1.209     brouard  2766: 
                   2767:     for(j=1; j<=nlstate; j++){
                   2768:       max[j]=0.;
                   2769:       min[j]=1.;
                   2770:     }
                   2771:     for(i=1;i<=nlstate;i++){
                   2772:       sumnew=0;
                   2773:       for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
                   2774:       for(j=1; j<=nlstate; j++){ 
                   2775:        prlim[i][j]= newm[i][j]/(1-sumnew);
                   2776:        max[j]=FMAX(max[j],prlim[i][j]);
                   2777:        min[j]=FMIN(min[j],prlim[i][j]);
                   2778:       }
                   2779:     }
                   2780: 
1.126     brouard  2781:     maxmax=0.;
1.209     brouard  2782:     for(j=1; j<=nlstate; j++){
                   2783:       meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
                   2784:       maxmax=FMAX(maxmax,meandiff[j]);
                   2785:       /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
1.169     brouard  2786:     } /* j loop */
1.203     brouard  2787:     *ncvyear= (int)age- (int)agefin;
1.208     brouard  2788:     /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.126     brouard  2789:     if(maxmax < ftolpl){
1.209     brouard  2790:       /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
                   2791:       free_vector(min,1,nlstate);
                   2792:       free_vector(max,1,nlstate);
                   2793:       free_vector(meandiff,1,nlstate);
1.126     brouard  2794:       return prlim;
                   2795:     }
1.288     brouard  2796:   } /* agefin loop */
1.208     brouard  2797:     /* After some age loop it doesn't converge */
1.288     brouard  2798:   if(!first){
                   2799:     first=1;
                   2800:     printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d). Others in log file only...\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2801:   }
                   2802:   fprintf(ficlog, "Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.d years and %d loops. Try to lower 'ftolpl'. Youngest age to start was %d=(%d-%d).\n", (int)age, maxmax, ftolpl, *ncvyear, ncvloop, (int)(agefin+stepm/YEARM),  (int)(age-stepm/YEARM), (int)delaymax);
                   2803: 
1.209     brouard  2804:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2805:   free_vector(min,1,nlstate);
                   2806:   free_vector(max,1,nlstate);
                   2807:   free_vector(meandiff,1,nlstate);
1.208     brouard  2808:   
1.169     brouard  2809:   return prlim; /* should not reach here */
1.126     brouard  2810: }
                   2811: 
1.217     brouard  2812: 
                   2813:  /**** Back Prevalence limit (stable or period prevalence)  ****************/
                   2814: 
1.218     brouard  2815:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ageminpar, double agemaxpar, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
                   2816:  /* double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, double ftolpl, int *ncvyear, int ij) */
1.242     brouard  2817:   double **bprevalim(double **bprlim, double ***prevacurrent, int nlstate, double x[], double age, double ftolpl, int *ncvyear, int ij, int nres)
1.217     brouard  2818: {
1.264     brouard  2819:   /* Computes the prevalence limit in each live state at age x and for covariate combination ij (<=2**cptcoveff) by left multiplying the unit
1.217     brouard  2820:      matrix by transitions matrix until convergence is reached with precision ftolpl */
                   2821:   /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
                   2822:   /* Wx is row vector: population in state 1, population in state 2, population dead */
                   2823:   /* or prevalence in state 1, prevalence in state 2, 0 */
                   2824:   /* newm is the matrix after multiplications, its rows are identical at a factor */
                   2825:   /* Initial matrix pimij */
                   2826:   /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
                   2827:   /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
                   2828:   /*  0,                   0                  , 1} */
                   2829:   /*
                   2830:    * and after some iteration: */
                   2831:   /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
                   2832:   /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
                   2833:   /*  0,                   0                  , 1} */
                   2834:   /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
                   2835:   /* {0.51571254859325999, 0.4842874514067399, */
                   2836:   /*  0.51326036147820708, 0.48673963852179264} */
                   2837:   /* If we start from prlim again, prlim tends to a constant matrix */
                   2838: 
                   2839:   int i, ii,j,k;
1.247     brouard  2840:   int first=0;
1.217     brouard  2841:   double *min, *max, *meandiff, maxmax,sumnew=0.;
                   2842:   /* double **matprod2(); */ /* test */
                   2843:   double **out, cov[NCOVMAX+1], **bmij();
                   2844:   double **newm;
1.218     brouard  2845:   double        **dnewm, **doldm, **dsavm;  /* for use */
                   2846:   double        **oldm, **savm;  /* for use */
                   2847: 
1.217     brouard  2848:   double agefin, delaymax=200. ; /* 100 Max number of years to converge */
                   2849:   int ncvloop=0;
                   2850:   
                   2851:   min=vector(1,nlstate);
                   2852:   max=vector(1,nlstate);
                   2853:   meandiff=vector(1,nlstate);
                   2854: 
1.266     brouard  2855:   dnewm=ddnewms; doldm=ddoldms; dsavm=ddsavms;
                   2856:   oldm=oldms; savm=savms;
                   2857:   
                   2858:   /* Starting with matrix unity */
                   2859:   for (ii=1;ii<=nlstate+ndeath;ii++)
                   2860:     for (j=1;j<=nlstate+ndeath;j++){
1.217     brouard  2861:       oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   2862:     }
                   2863:   
                   2864:   cov[1]=1.;
                   2865:   
                   2866:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   2867:   /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
1.218     brouard  2868:   /* for(agefin=age+stepm/YEARM; agefin<=age+delaymax; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
1.288     brouard  2869:   /* for(agefin=age; agefin<AGESUP; agefin=agefin+stepm/YEARM){ /\* A changer en age *\/ */
                   2870:   for(agefin=age; agefin<FMIN(AGESUP,age+delaymax); agefin=agefin+stepm/YEARM){ /* A changer en age */
1.217     brouard  2871:     ncvloop++;
1.218     brouard  2872:     newm=savm; /* oldm should be kept from previous iteration or unity at start */
                   2873:                /* newm points to the allocated table savm passed by the function it can be written, savm could be reallocated */
1.217     brouard  2874:     /* Covariates have to be included here again */
                   2875:     cov[2]=agefin;
                   2876:     if(nagesqr==1)
                   2877:       cov[3]= agefin*agefin;;
1.242     brouard  2878:     for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   2879:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   2880:       cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
1.264     brouard  2881:       /* printf("bprevalim Dummy agefin=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agefin,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
1.242     brouard  2882:     }
                   2883:     /* for (k=1; k<=cptcovn;k++) { */
                   2884:     /*   /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   2885:     /*   cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   2886:     /*   /\* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); *\/ */
                   2887:     /* } */
                   2888:     for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   2889:                        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   2890:       cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   2891:       /* printf("prevalim Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   2892:     }
                   2893:     /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2]; */
                   2894:     /* for (k=1; k<=cptcovprod;k++) /\* Useless *\/ */
                   2895:     /*   /\* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; *\/ */
                   2896:     /*   cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)]; */
                   2897:     for (k=1; k<=cptcovage;k++){  /* For product with age */
                   2898:       if(Dummy[Tvar[Tage[k]]]){
                   2899:        cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   2900:       } else{
                   2901:        cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   2902:       }
                   2903:       /* printf("prevalim Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   2904:     }
                   2905:     for (k=1; k<=cptcovprod;k++){ /* For product without age */
                   2906:       /* printf("prevalim Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   2907:       if(Dummy[Tvard[k][1]==0]){
                   2908:        if(Dummy[Tvard[k][2]==0]){
                   2909:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   2910:        }else{
                   2911:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * Tqresult[nres][k];
                   2912:        }
                   2913:       }else{
                   2914:        if(Dummy[Tvard[k][2]==0]){
                   2915:          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][2]][codtabm(ij,k)] * Tqinvresult[nres][Tvard[k][1]];
                   2916:        }else{
                   2917:          cov[2+nagesqr+Tprod[k]]=Tqinvresult[nres][Tvard[k][1]]*  Tqinvresult[nres][Tvard[k][2]];
                   2918:        }
                   2919:       }
1.217     brouard  2920:     }
                   2921:     
                   2922:     /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
                   2923:     /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
                   2924:     /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
                   2925:     /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   2926:     /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
1.218     brouard  2927:                /* ij should be linked to the correct index of cov */
                   2928:                /* age and covariate values ij are in 'cov', but we need to pass
                   2929:                 * ij for the observed prevalence at age and status and covariate
                   2930:                 * number:  prevacurrent[(int)agefin][ii][ij]
                   2931:                 */
                   2932:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, ageminpar, agemaxpar, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2933:     /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij)); /\* Bug Valgrind *\/ */
                   2934:     out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij)); /* Bug Valgrind */
1.268     brouard  2935:     /* if((int)age == 86 || (int)age == 87){ */
1.266     brouard  2936:     /*   printf(" Backward prevalim age=%d agefin=%d \n", (int) age, (int) agefin); */
                   2937:     /*   for(i=1; i<=nlstate+ndeath; i++) { */
                   2938:     /*         printf("%d newm= ",i); */
                   2939:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2940:     /*           printf("%f ",newm[i][j]); */
                   2941:     /*         } */
                   2942:     /*         printf("oldm * "); */
                   2943:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2944:     /*           printf("%f ",oldm[i][j]); */
                   2945:     /*         } */
1.268     brouard  2946:     /*         printf(" bmmij "); */
1.266     brouard  2947:     /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   2948:     /*           printf("%f ",pmmij[i][j]); */
                   2949:     /*         } */
                   2950:     /*         printf("\n"); */
                   2951:     /*   } */
                   2952:     /* } */
1.217     brouard  2953:     savm=oldm;
                   2954:     oldm=newm;
1.266     brouard  2955: 
1.217     brouard  2956:     for(j=1; j<=nlstate; j++){
                   2957:       max[j]=0.;
                   2958:       min[j]=1.;
                   2959:     }
                   2960:     for(j=1; j<=nlstate; j++){ 
                   2961:       for(i=1;i<=nlstate;i++){
1.234     brouard  2962:        /* bprlim[i][j]= newm[i][j]/(1-sumnew); */
                   2963:        bprlim[i][j]= newm[i][j];
                   2964:        max[i]=FMAX(max[i],bprlim[i][j]); /* Max in line */
                   2965:        min[i]=FMIN(min[i],bprlim[i][j]);
1.217     brouard  2966:       }
                   2967:     }
1.218     brouard  2968:                
1.217     brouard  2969:     maxmax=0.;
                   2970:     for(i=1; i<=nlstate; i++){
                   2971:       meandiff[i]=(max[i]-min[i])/(max[i]+min[i])*2.; /* mean difference for each column */
                   2972:       maxmax=FMAX(maxmax,meandiff[i]);
                   2973:       /* printf("Back age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, i, meandiff[i],(int)agefin, i, max[i], i, min[i],maxmax); */
1.268     brouard  2974:     } /* i loop */
1.217     brouard  2975:     *ncvyear= -( (int)age- (int)agefin);
1.268     brouard  2976:     /* printf("Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2977:     if(maxmax < ftolpl){
1.220     brouard  2978:       /* printf("OK Back maxmax=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
1.217     brouard  2979:       free_vector(min,1,nlstate);
                   2980:       free_vector(max,1,nlstate);
                   2981:       free_vector(meandiff,1,nlstate);
                   2982:       return bprlim;
                   2983:     }
1.288     brouard  2984:   } /* agefin loop */
1.217     brouard  2985:     /* After some age loop it doesn't converge */
1.288     brouard  2986:   if(!first){
1.247     brouard  2987:     first=1;
                   2988:     printf("Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. Others in log file only...\n\
                   2989: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2990:   }
                   2991:   fprintf(ficlog,"Warning: the back stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
1.217     brouard  2992: Oldest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
                   2993:   /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
                   2994:   free_vector(min,1,nlstate);
                   2995:   free_vector(max,1,nlstate);
                   2996:   free_vector(meandiff,1,nlstate);
                   2997:   
                   2998:   return bprlim; /* should not reach here */
                   2999: }
                   3000: 
1.126     brouard  3001: /*************** transition probabilities ***************/ 
                   3002: 
                   3003: double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
                   3004: {
1.138     brouard  3005:   /* According to parameters values stored in x and the covariate's values stored in cov,
1.266     brouard  3006:      computes the probability to be observed in state j (after stepm years) being in state i by appying the
1.138     brouard  3007:      model to the ncovmodel covariates (including constant and age).
                   3008:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3009:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3010:      ncth covariate in the global vector x is given by the formula:
                   3011:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3012:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3013:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3014:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
1.266     brouard  3015:      Outputs ps[i][j] or probability to be observed in j being in i according to
1.138     brouard  3016:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
1.266     brouard  3017:      Sum on j ps[i][j] should equal to 1.
1.138     brouard  3018:   */
                   3019:   double s1, lnpijopii;
1.126     brouard  3020:   /*double t34;*/
1.164     brouard  3021:   int i,j, nc, ii, jj;
1.126     brouard  3022: 
1.223     brouard  3023:   for(i=1; i<= nlstate; i++){
                   3024:     for(j=1; j<i;j++){
                   3025:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3026:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3027:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3028:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3029:       }
                   3030:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3031:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3032:     }
                   3033:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3034:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3035:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3036:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3037:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3038:       }
                   3039:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3040:     }
                   3041:   }
1.218     brouard  3042:   
1.223     brouard  3043:   for(i=1; i<= nlstate; i++){
                   3044:     s1=0;
                   3045:     for(j=1; j<i; j++){
                   3046:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3047:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3048:     }
                   3049:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3050:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3051:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3052:     }
                   3053:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3054:     ps[i][i]=1./(s1+1.);
                   3055:     /* Computing other pijs */
                   3056:     for(j=1; j<i; j++)
                   3057:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3058:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3059:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3060:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3061:   } /* end i */
1.218     brouard  3062:   
1.223     brouard  3063:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3064:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3065:       ps[ii][jj]=0;
                   3066:       ps[ii][ii]=1;
                   3067:     }
                   3068:   }
1.294     brouard  3069: 
                   3070: 
1.223     brouard  3071:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3072:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3073:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3074:   /*   } */
                   3075:   /*   printf("\n "); */
                   3076:   /* } */
                   3077:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3078:   /*
                   3079:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
1.218     brouard  3080:                goto end;*/
1.266     brouard  3081:   return ps; /* Pointer is unchanged since its call */
1.126     brouard  3082: }
                   3083: 
1.218     brouard  3084: /*************** backward transition probabilities ***************/ 
                   3085: 
                   3086:  /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ageminpar, double agemaxpar, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3087: /* double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, double ***dnewm, double **doldm, double **dsavm, int ij ) */
                   3088:  double **bmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate,  double ***prevacurrent, int ij )
                   3089: {
1.302     brouard  3090:   /* Computes the backward probability at age agefin, cov[2], and covariate combination 'ij'. In fact cov is already filled and x too.
1.266     brouard  3091:    * Call to pmij(cov and x), call to cross prevalence, sums and inverses, left multiply, and returns in **ps as well as **bmij.
1.222     brouard  3092:    */
1.218     brouard  3093:   int i, ii, j,k;
1.222     brouard  3094:   
                   3095:   double **out, **pmij();
                   3096:   double sumnew=0.;
1.218     brouard  3097:   double agefin;
1.292     brouard  3098:   double k3=0.; /* constant of the w_x diagonal matrix (in order for B to sum to 1 even for death state) */
1.222     brouard  3099:   double **dnewm, **dsavm, **doldm;
                   3100:   double **bbmij;
                   3101:   
1.218     brouard  3102:   doldm=ddoldms; /* global pointers */
1.222     brouard  3103:   dnewm=ddnewms;
                   3104:   dsavm=ddsavms;
                   3105:   
                   3106:   agefin=cov[2];
1.268     brouard  3107:   /* Bx = Diag(w_x) P_x Diag(Sum_i w^i_x p^ij_x */
1.222     brouard  3108:   /* bmij *//* age is cov[2], ij is included in cov, but we need for
1.266     brouard  3109:      the observed prevalence (with this covariate ij) at beginning of transition */
                   3110:   /* dsavm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
1.268     brouard  3111: 
                   3112:   /* P_x */
1.266     brouard  3113:   pmmij=pmij(pmmij,cov,ncovmodel,x,nlstate); /*This is forward probability from agefin to agefin + stepm */
1.268     brouard  3114:   /* outputs pmmij which is a stochastic matrix in row */
                   3115: 
                   3116:   /* Diag(w_x) */
1.292     brouard  3117:   /* Rescaling the cross-sectional prevalence: Problem with prevacurrent which can be zero */
1.268     brouard  3118:   sumnew=0.;
1.269     brouard  3119:   /*for (ii=1;ii<=nlstate+ndeath;ii++){*/
1.268     brouard  3120:   for (ii=1;ii<=nlstate;ii++){ /* Only on live states */
1.297     brouard  3121:     /* printf(" agefin=%d, ii=%d, ij=%d, prev=%f\n",(int)agefin,ii, ij, prevacurrent[(int)agefin][ii][ij]); */
1.268     brouard  3122:     sumnew+=prevacurrent[(int)agefin][ii][ij];
                   3123:   }
                   3124:   if(sumnew >0.01){  /* At least some value in the prevalence */
                   3125:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3126:       for (j=1;j<=nlstate+ndeath;j++)
1.269     brouard  3127:        doldm[ii][j]=(ii==j ? prevacurrent[(int)agefin][ii][ij]/sumnew : 0.0);
1.268     brouard  3128:     }
                   3129:   }else{
                   3130:     for (ii=1;ii<=nlstate+ndeath;ii++){
                   3131:       for (j=1;j<=nlstate+ndeath;j++)
                   3132:       doldm[ii][j]=(ii==j ? 1./nlstate : 0.0);
                   3133:     }
                   3134:     /* if(sumnew <0.9){ */
                   3135:     /*   printf("Problem internal bmij B: sum on i wi <0.9: j=%d, sum_i wi=%lf,agefin=%d\n",j,sumnew, (int)agefin); */
                   3136:     /* } */
                   3137:   }
                   3138:   k3=0.0;  /* We put the last diagonal to 0 */
                   3139:   for (ii=nlstate+1;ii<=nlstate+ndeath;ii++){
                   3140:       doldm[ii][ii]= k3;
                   3141:   }
                   3142:   /* End doldm, At the end doldm is diag[(w_i)] */
                   3143:   
1.292     brouard  3144:   /* Left product of this diag matrix by pmmij=Px (dnewm=dsavm*doldm): diag[(w_i)*Px */
                   3145:   bbmij=matprod2(dnewm, doldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, pmmij); /* was a Bug Valgrind */
1.268     brouard  3146: 
1.292     brouard  3147:   /* Diag(Sum_i w^i_x p^ij_x, should be the prevalence at age x+stepm */
1.268     brouard  3148:   /* w1 p11 + w2 p21 only on live states N1./N..*N11/N1. + N2./N..*N21/N2.=(N11+N21)/N..=N.1/N.. */
1.222     brouard  3149:   for (j=1;j<=nlstate+ndeath;j++){
1.268     brouard  3150:     sumnew=0.;
1.222     brouard  3151:     for (ii=1;ii<=nlstate;ii++){
1.266     brouard  3152:       /* sumnew+=dsavm[ii][j]*prevacurrent[(int)agefin][ii][ij]; */
1.268     brouard  3153:       sumnew+=pmmij[ii][j]*doldm[ii][ii]; /* Yes prevalence at beginning of transition */
1.222     brouard  3154:     } /* sumnew is (N11+N21)/N..= N.1/N.. = sum on i of w_i pij */
1.268     brouard  3155:     for (ii=1;ii<=nlstate+ndeath;ii++){
1.222     brouard  3156:        /* if(agefin >= agemaxpar && agefin <= agemaxpar+stepm/YEARM){ */
1.268     brouard  3157:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3158:        /* }else if(agefin >= agemaxpar+stepm/YEARM){ */
1.268     brouard  3159:        /*      dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0); */
1.222     brouard  3160:        /* }else */
1.268     brouard  3161:       dsavm[ii][j]=(ii==j ? 1./sumnew : 0.0);
                   3162:     } /*End ii */
                   3163:   } /* End j, At the end dsavm is diag[1/(w_1p1i+w_2 p2i)] for ALL states even if the sum is only for live states */
                   3164: 
1.292     brouard  3165:   ps=matprod2(ps, dnewm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, dsavm); /* was a Bug Valgrind */
1.268     brouard  3166:   /* ps is now diag[w_i] * Px * diag [1/(w_1p1i+w_2 p2i)] */
1.222     brouard  3167:   /* end bmij */
1.266     brouard  3168:   return ps; /*pointer is unchanged */
1.218     brouard  3169: }
1.217     brouard  3170: /*************** transition probabilities ***************/ 
                   3171: 
1.218     brouard  3172: double **bpmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
1.217     brouard  3173: {
                   3174:   /* According to parameters values stored in x and the covariate's values stored in cov,
                   3175:      computes the probability to be observed in state j being in state i by appying the
                   3176:      model to the ncovmodel covariates (including constant and age).
                   3177:      lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
                   3178:      and, according on how parameters are entered, the position of the coefficient xij(nc) of the
                   3179:      ncth covariate in the global vector x is given by the formula:
                   3180:      j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
                   3181:      j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
                   3182:      Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
                   3183:      sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
                   3184:      Outputs ps[i][j] the probability to be observed in j being in j according to
                   3185:      the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
                   3186:   */
                   3187:   double s1, lnpijopii;
                   3188:   /*double t34;*/
                   3189:   int i,j, nc, ii, jj;
                   3190: 
1.234     brouard  3191:   for(i=1; i<= nlstate; i++){
                   3192:     for(j=1; j<i;j++){
                   3193:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3194:        /*lnpijopii += param[i][j][nc]*cov[nc];*/
                   3195:        lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
                   3196:        /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3197:       }
                   3198:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3199:       /*       printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
                   3200:     }
                   3201:     for(j=i+1; j<=nlstate+ndeath;j++){
                   3202:       for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
                   3203:        /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
                   3204:        lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
                   3205:        /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
                   3206:       }
                   3207:       ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
                   3208:     }
                   3209:   }
                   3210:   
                   3211:   for(i=1; i<= nlstate; i++){
                   3212:     s1=0;
                   3213:     for(j=1; j<i; j++){
                   3214:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3215:       /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3216:     }
                   3217:     for(j=i+1; j<=nlstate+ndeath; j++){
                   3218:       s1+=exp(ps[i][j]); /* In fact sums pij/pii */
                   3219:       /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
                   3220:     }
                   3221:     /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
                   3222:     ps[i][i]=1./(s1+1.);
                   3223:     /* Computing other pijs */
                   3224:     for(j=1; j<i; j++)
                   3225:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3226:     for(j=i+1; j<=nlstate+ndeath; j++)
                   3227:       ps[i][j]= exp(ps[i][j])*ps[i][i];
                   3228:     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
                   3229:   } /* end i */
                   3230:   
                   3231:   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
                   3232:     for(jj=1; jj<= nlstate+ndeath; jj++){
                   3233:       ps[ii][jj]=0;
                   3234:       ps[ii][ii]=1;
                   3235:     }
                   3236:   }
1.296     brouard  3237:   /* Added for prevbcast */ /* Transposed matrix too */
1.234     brouard  3238:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3239:     s1=0.;
                   3240:     for(ii=1; ii<= nlstate+ndeath; ii++){
                   3241:       s1+=ps[ii][jj];
                   3242:     }
                   3243:     for(ii=1; ii<= nlstate; ii++){
                   3244:       ps[ii][jj]=ps[ii][jj]/s1;
                   3245:     }
                   3246:   }
                   3247:   /* Transposition */
                   3248:   for(jj=1; jj<= nlstate+ndeath; jj++){
                   3249:     for(ii=jj; ii<= nlstate+ndeath; ii++){
                   3250:       s1=ps[ii][jj];
                   3251:       ps[ii][jj]=ps[jj][ii];
                   3252:       ps[jj][ii]=s1;
                   3253:     }
                   3254:   }
                   3255:   /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
                   3256:   /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
                   3257:   /*   printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
                   3258:   /*   } */
                   3259:   /*   printf("\n "); */
                   3260:   /* } */
                   3261:   /* printf("\n ");printf("%lf ",cov[2]);*/
                   3262:   /*
                   3263:     for(i=1; i<= npar; i++) printf("%f ",x[i]);
                   3264:     goto end;*/
                   3265:   return ps;
1.217     brouard  3266: }
                   3267: 
                   3268: 
1.126     brouard  3269: /**************** Product of 2 matrices ******************/
                   3270: 
1.145     brouard  3271: double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
1.126     brouard  3272: {
                   3273:   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
                   3274:      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
                   3275:   /* in, b, out are matrice of pointers which should have been initialized 
                   3276:      before: only the contents of out is modified. The function returns
                   3277:      a pointer to pointers identical to out */
1.145     brouard  3278:   int i, j, k;
1.126     brouard  3279:   for(i=nrl; i<= nrh; i++)
1.145     brouard  3280:     for(k=ncolol; k<=ncoloh; k++){
                   3281:       out[i][k]=0.;
                   3282:       for(j=ncl; j<=nch; j++)
                   3283:        out[i][k] +=in[i][j]*b[j][k];
                   3284:     }
1.126     brouard  3285:   return out;
                   3286: }
                   3287: 
                   3288: 
                   3289: /************* Higher Matrix Product ***************/
                   3290: 
1.235     brouard  3291: double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij, int nres )
1.126     brouard  3292: {
1.218     brouard  3293:   /* Computes the transition matrix starting at age 'age' and combination of covariate values corresponding to ij over 
1.126     brouard  3294:      'nhstepm*hstepm*stepm' months (i.e. until
                   3295:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
                   3296:      nhstepm*hstepm matrices. 
                   3297:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
                   3298:      (typically every 2 years instead of every month which is too big 
                   3299:      for the memory).
                   3300:      Model is determined by parameters x and covariates have to be 
                   3301:      included manually here. 
                   3302: 
                   3303:      */
                   3304: 
                   3305:   int i, j, d, h, k;
1.131     brouard  3306:   double **out, cov[NCOVMAX+1];
1.126     brouard  3307:   double **newm;
1.187     brouard  3308:   double agexact;
1.214     brouard  3309:   double agebegin, ageend;
1.126     brouard  3310: 
                   3311:   /* Hstepm could be zero and should return the unit matrix */
                   3312:   for (i=1;i<=nlstate+ndeath;i++)
                   3313:     for (j=1;j<=nlstate+ndeath;j++){
                   3314:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3315:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3316:     }
                   3317:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3318:   for(h=1; h <=nhstepm; h++){
                   3319:     for(d=1; d <=hstepm; d++){
                   3320:       newm=savm;
                   3321:       /* Covariates have to be included here again */
                   3322:       cov[1]=1.;
1.214     brouard  3323:       agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /* age just before transition */
1.187     brouard  3324:       cov[2]=agexact;
                   3325:       if(nagesqr==1)
1.227     brouard  3326:        cov[3]= agexact*agexact;
1.235     brouard  3327:       for (k=1; k<=nsd;k++) { /* For single dummy covariates only */
                   3328:                        /* Here comes the value of the covariate 'ij' after renumbering k with single dummy covariates */
                   3329:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3330:        /* printf("hpxij Dummy combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3331:       }
                   3332:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3333:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3334:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3335:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3336:       }
                   3337:       for (k=1; k<=cptcovage;k++){
                   3338:        if(Dummy[Tvar[Tage[k]]]){
                   3339:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3340:        } else{
                   3341:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3342:        }
                   3343:        /* printf("hPxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3344:       }
                   3345:       for (k=1; k<=cptcovprod;k++){ /*  */
                   3346:        /* printf("hPxij Prod ij=%d k=%d  Tprod[%d]=%d Tvard[%d][1]=V%d, Tvard[%d][2]=V%d\n",ij,k,k,Tprod[k], k,Tvard[k][1], k,Tvard[k][2]); */
                   3347:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
                   3348:       }
                   3349:       /* for (k=1; k<=cptcovn;k++)  */
                   3350:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3351:       /* for (k=1; k<=cptcovage;k++) /\* Should start at cptcovn+1 *\/ */
                   3352:       /*       cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2]; */
                   3353:       /* for (k=1; k<=cptcovprod;k++) /\* Useless because included in cptcovn *\/ */
                   3354:       /*       cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)]; */
1.227     brouard  3355:       
                   3356:       
1.126     brouard  3357:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3358:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.218     brouard  3359:                        /* right multiplication of oldm by the current matrix */
1.126     brouard  3360:       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
                   3361:                   pmij(pmmij,cov,ncovmodel,x,nlstate));
1.217     brouard  3362:       /* if((int)age == 70){ */
                   3363:       /*       printf(" Forward hpxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3364:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3365:       /*         printf("%d pmmij ",i); */
                   3366:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3367:       /*           printf("%f ",pmmij[i][j]); */
                   3368:       /*         } */
                   3369:       /*         printf(" oldm "); */
                   3370:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3371:       /*           printf("%f ",oldm[i][j]); */
                   3372:       /*         } */
                   3373:       /*         printf("\n"); */
                   3374:       /*       } */
                   3375:       /* } */
1.126     brouard  3376:       savm=oldm;
                   3377:       oldm=newm;
                   3378:     }
                   3379:     for(i=1; i<=nlstate+ndeath; i++)
                   3380:       for(j=1;j<=nlstate+ndeath;j++) {
1.267     brouard  3381:        po[i][j][h]=newm[i][j];
                   3382:        /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
1.126     brouard  3383:       }
1.128     brouard  3384:     /*printf("h=%d ",h);*/
1.126     brouard  3385:   } /* end h */
1.267     brouard  3386:   /*     printf("\n H=%d \n",h); */
1.126     brouard  3387:   return po;
                   3388: }
                   3389: 
1.217     brouard  3390: /************* Higher Back Matrix Product ***************/
1.218     brouard  3391: /* double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, double **oldm, double **savm, double **dnewm, double **doldm, double **dsavm, int ij ) */
1.267     brouard  3392: double ***hbxij(double ***po, int nhstepm, double age, int hstepm, double *x, double ***prevacurrent, int nlstate, int stepm, int ij, int nres )
1.217     brouard  3393: {
1.266     brouard  3394:   /* For a combination of dummy covariate ij, computes the transition matrix starting at age 'age' over
1.217     brouard  3395:      'nhstepm*hstepm*stepm' months (i.e. until
1.218     brouard  3396:      age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying
                   3397:      nhstepm*hstepm matrices.
                   3398:      Output is stored in matrix po[i][j][h] for h every 'hstepm' step
                   3399:      (typically every 2 years instead of every month which is too big
1.217     brouard  3400:      for the memory).
1.218     brouard  3401:      Model is determined by parameters x and covariates have to be
1.266     brouard  3402:      included manually here. Then we use a call to bmij(x and cov)
                   3403:      The addresss of po (p3mat allocated to the dimension of nhstepm) should be stored for output
1.222     brouard  3404:   */
1.217     brouard  3405: 
                   3406:   int i, j, d, h, k;
1.266     brouard  3407:   double **out, cov[NCOVMAX+1], **bmij();
                   3408:   double **newm, ***newmm;
1.217     brouard  3409:   double agexact;
                   3410:   double agebegin, ageend;
1.222     brouard  3411:   double **oldm, **savm;
1.217     brouard  3412: 
1.266     brouard  3413:   newmm=po; /* To be saved */
                   3414:   oldm=oldms;savm=savms; /* Global pointers */
1.217     brouard  3415:   /* Hstepm could be zero and should return the unit matrix */
                   3416:   for (i=1;i<=nlstate+ndeath;i++)
                   3417:     for (j=1;j<=nlstate+ndeath;j++){
                   3418:       oldm[i][j]=(i==j ? 1.0 : 0.0);
                   3419:       po[i][j][0]=(i==j ? 1.0 : 0.0);
                   3420:     }
                   3421:   /* Even if hstepm = 1, at least one multiplication by the unit matrix */
                   3422:   for(h=1; h <=nhstepm; h++){
                   3423:     for(d=1; d <=hstepm; d++){
                   3424:       newm=savm;
                   3425:       /* Covariates have to be included here again */
                   3426:       cov[1]=1.;
1.271     brouard  3427:       agexact=age-( (h-1)*hstepm + (d)  )*stepm/YEARM; /* age just before transition, d or d-1? */
1.217     brouard  3428:       /* agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM; /\* age just before transition *\/ */
                   3429:       cov[2]=agexact;
                   3430:       if(nagesqr==1)
1.222     brouard  3431:        cov[3]= agexact*agexact;
1.266     brouard  3432:       for (k=1; k<=cptcovn;k++){
                   3433:       /*       cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)]; */
                   3434:       /* /\* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; *\/ */
                   3435:        cov[2+nagesqr+TvarsDind[k]]=nbcode[TvarsD[k]][codtabm(ij,k)];
                   3436:         /* printf("hbxij Dummy agexact=%.0f combi=%d k=%d TvarsD[%d]=V%d TvarsDind[%d]=%d nbcode=%d cov[%d]=%lf codtabm(%d,Tvar[%d])=%d \n",agexact,ij,k, k, TvarsD[k],k,TvarsDind[k],nbcode[TvarsD[k]][codtabm(ij,k)],2+nagesqr+TvarsDind[k],cov[2+nagesqr+TvarsDind[k]], ij, k, codtabm(ij,k)); */
                   3437:       }
1.267     brouard  3438:       for (k=1; k<=nsq;k++) { /* For single varying covariates only */
                   3439:        /* Here comes the value of quantitative after renumbering k with single quantitative covariates */
                   3440:        cov[2+nagesqr+TvarsQind[k]]=Tqresult[nres][k]; 
                   3441:        /* printf("hPxij Quantitative k=%d  TvarsQind[%d]=%d, TvarsQ[%d]=V%d,Tqresult[%d][%d]=%f\n",k,k,TvarsQind[k],k,TvarsQ[k],nres,k,Tqresult[nres][k]); */
                   3442:       }
                   3443:       for (k=1; k<=cptcovage;k++){ /* Should start at cptcovn+1 */
                   3444:        if(Dummy[Tvar[Tage[k]]]){
                   3445:          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   3446:        } else{
                   3447:          cov[2+nagesqr+Tage[k]]=Tqresult[nres][k]; 
                   3448:        }
                   3449:        /* printf("hBxij Age combi=%d k=%d  Tage[%d]=V%d Tqresult[%d][%d]=%f\n",ij,k,k,Tage[k],nres,k,Tqresult[nres][k]); */
                   3450:       }
                   3451:       for (k=1; k<=cptcovprod;k++){ /* Useless because included in cptcovn */
1.222     brouard  3452:        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.267     brouard  3453:       }                        
1.217     brouard  3454:       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
                   3455:       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
1.267     brouard  3456: 
1.218     brouard  3457:       /* Careful transposed matrix */
1.266     brouard  3458:       /* age is in cov[2], prevacurrent at beginning of transition. */
1.218     brouard  3459:       /* out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent, dnewm, doldm, dsavm,ij),\ */
1.222     brouard  3460:       /*                                                1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); */
1.218     brouard  3461:       out=matprod2(newm, bmij(pmmij,cov,ncovmodel,x,nlstate,prevacurrent,ij),\
1.222     brouard  3462:                   1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);
1.217     brouard  3463:       /* if((int)age == 70){ */
                   3464:       /*       printf(" Backward hbxij age=%d agexact=%f d=%d nhstepm=%d hstepm=%d\n", (int) age, agexact, d, nhstepm, hstepm); */
                   3465:       /*       for(i=1; i<=nlstate+ndeath; i++) { */
                   3466:       /*         printf("%d pmmij ",i); */
                   3467:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3468:       /*           printf("%f ",pmmij[i][j]); */
                   3469:       /*         } */
                   3470:       /*         printf(" oldm "); */
                   3471:       /*         for(j=1;j<=nlstate+ndeath;j++) { */
                   3472:       /*           printf("%f ",oldm[i][j]); */
                   3473:       /*         } */
                   3474:       /*         printf("\n"); */
                   3475:       /*       } */
                   3476:       /* } */
                   3477:       savm=oldm;
                   3478:       oldm=newm;
                   3479:     }
                   3480:     for(i=1; i<=nlstate+ndeath; i++)
                   3481:       for(j=1;j<=nlstate+ndeath;j++) {
1.222     brouard  3482:        po[i][j][h]=newm[i][j];
1.268     brouard  3483:        /* if(h==nhstepm) */
                   3484:        /*   printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]); */
1.217     brouard  3485:       }
1.268     brouard  3486:     /* printf("h=%d %.1f ",h, agexact); */
1.217     brouard  3487:   } /* end h */
1.268     brouard  3488:   /* printf("\n H=%d nhs=%d \n",h, nhstepm); */
1.217     brouard  3489:   return po;
                   3490: }
                   3491: 
                   3492: 
1.162     brouard  3493: #ifdef NLOPT
                   3494:   double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
                   3495:   double fret;
                   3496:   double *xt;
                   3497:   int j;
                   3498:   myfunc_data *d2 = (myfunc_data *) pd;
                   3499: /* xt = (p1-1); */
                   3500:   xt=vector(1,n); 
                   3501:   for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
                   3502: 
                   3503:   fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
                   3504:   /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
                   3505:   printf("Function = %.12lf ",fret);
                   3506:   for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
                   3507:   printf("\n");
                   3508:  free_vector(xt,1,n);
                   3509:   return fret;
                   3510: }
                   3511: #endif
1.126     brouard  3512: 
                   3513: /*************** log-likelihood *************/
                   3514: double func( double *x)
                   3515: {
1.226     brouard  3516:   int i, ii, j, k, mi, d, kk;
                   3517:   int ioffset=0;
                   3518:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
                   3519:   double **out;
                   3520:   double lli; /* Individual log likelihood */
                   3521:   int s1, s2;
1.228     brouard  3522:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
1.226     brouard  3523:   double bbh, survp;
                   3524:   long ipmx;
                   3525:   double agexact;
                   3526:   /*extern weight */
                   3527:   /* We are differentiating ll according to initial status */
                   3528:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3529:   /*for(i=1;i<imx;i++) 
                   3530:     printf(" %d\n",s[4][i]);
                   3531:   */
1.162     brouard  3532: 
1.226     brouard  3533:   ++countcallfunc;
1.162     brouard  3534: 
1.226     brouard  3535:   cov[1]=1.;
1.126     brouard  3536: 
1.226     brouard  3537:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3538:   ioffset=0;
1.226     brouard  3539:   if(mle==1){
                   3540:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3541:       /* Computes the values of the ncovmodel covariates of the model
                   3542:         depending if the covariates are fixed or varying (age dependent) and stores them in cov[]
                   3543:         Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                   3544:         to be observed in j being in i according to the model.
                   3545:       */
1.243     brouard  3546:       ioffset=2+nagesqr ;
1.233     brouard  3547:    /* Fixed */
1.234     brouard  3548:       for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products */
                   3549:        cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3550:       }
1.226     brouard  3551:       /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
                   3552:         is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
                   3553:         has been calculated etc */
                   3554:       /* For an individual i, wav[i] gives the number of effective waves */
                   3555:       /* We compute the contribution to Likelihood of each effective transition
                   3556:         mw[mi][i] is real wave of the mi th effectve wave */
                   3557:       /* Then statuses are computed at each begin and end of an effective wave s1=s[ mw[mi][i] ][i];
                   3558:         s2=s[mw[mi+1][i]][i];
                   3559:         And the iv th varying covariate is the cotvar[mw[mi+1][i]][iv][i]
                   3560:         But if the variable is not in the model TTvar[iv] is the real variable effective in the model:
                   3561:         meaning that decodemodel should be used cotvar[mw[mi+1][i]][TTvar[iv]][i]
                   3562:       */
                   3563:       for(mi=1; mi<= wav[i]-1; mi++){
1.234     brouard  3564:        for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3565:          /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3566:          cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
1.234     brouard  3567:        }
                   3568:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3569:          for (j=1;j<=nlstate+ndeath;j++){
                   3570:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3571:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3572:          }
                   3573:        for(d=0; d<dh[mi][i]; d++){
                   3574:          newm=savm;
                   3575:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3576:          cov[2]=agexact;
                   3577:          if(nagesqr==1)
                   3578:            cov[3]= agexact*agexact;  /* Should be changed here */
                   3579:          for (kk=1; kk<=cptcovage;kk++) {
1.242     brouard  3580:          if(!FixedV[Tvar[Tage[kk]]])
1.234     brouard  3581:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
1.242     brouard  3582:          else
                   3583:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
1.234     brouard  3584:          }
                   3585:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3586:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3587:          savm=oldm;
                   3588:          oldm=newm;
                   3589:        } /* end mult */
                   3590:        
                   3591:        /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
                   3592:        /* But now since version 0.9 we anticipate for bias at large stepm.
                   3593:         * If stepm is larger than one month (smallest stepm) and if the exact delay 
                   3594:         * (in months) between two waves is not a multiple of stepm, we rounded to 
                   3595:         * the nearest (and in case of equal distance, to the lowest) interval but now
                   3596:         * we keep into memory the bias bh[mi][i] and also the previous matrix product
                   3597:         * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
                   3598:         * probability in order to take into account the bias as a fraction of the way
1.231     brouard  3599:                                 * from savm to out if bh is negative or even beyond if bh is positive. bh varies
                   3600:                                 * -stepm/2 to stepm/2 .
                   3601:                                 * For stepm=1 the results are the same as for previous versions of Imach.
                   3602:                                 * For stepm > 1 the results are less biased than in previous versions. 
                   3603:                                 */
1.234     brouard  3604:        s1=s[mw[mi][i]][i];
                   3605:        s2=s[mw[mi+1][i]][i];
                   3606:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3607:        /* bias bh is positive if real duration
                   3608:         * is higher than the multiple of stepm and negative otherwise.
                   3609:         */
                   3610:        /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
                   3611:        if( s2 > nlstate){ 
                   3612:          /* i.e. if s2 is a death state and if the date of death is known 
                   3613:             then the contribution to the likelihood is the probability to 
                   3614:             die between last step unit time and current  step unit time, 
                   3615:             which is also equal to probability to die before dh 
                   3616:             minus probability to die before dh-stepm . 
                   3617:             In version up to 0.92 likelihood was computed
                   3618:             as if date of death was unknown. Death was treated as any other
                   3619:             health state: the date of the interview describes the actual state
                   3620:             and not the date of a change in health state. The former idea was
                   3621:             to consider that at each interview the state was recorded
                   3622:             (healthy, disable or death) and IMaCh was corrected; but when we
                   3623:             introduced the exact date of death then we should have modified
                   3624:             the contribution of an exact death to the likelihood. This new
                   3625:             contribution is smaller and very dependent of the step unit
                   3626:             stepm. It is no more the probability to die between last interview
                   3627:             and month of death but the probability to survive from last
                   3628:             interview up to one month before death multiplied by the
                   3629:             probability to die within a month. Thanks to Chris
                   3630:             Jackson for correcting this bug.  Former versions increased
                   3631:             mortality artificially. The bad side is that we add another loop
                   3632:             which slows down the processing. The difference can be up to 10%
                   3633:             lower mortality.
                   3634:          */
                   3635:          /* If, at the beginning of the maximization mostly, the
                   3636:             cumulative probability or probability to be dead is
                   3637:             constant (ie = 1) over time d, the difference is equal to
                   3638:             0.  out[s1][3] = savm[s1][3]: probability, being at state
                   3639:             s1 at precedent wave, to be dead a month before current
                   3640:             wave is equal to probability, being at state s1 at
                   3641:             precedent wave, to be dead at mont of the current
                   3642:             wave. Then the observed probability (that this person died)
                   3643:             is null according to current estimated parameter. In fact,
                   3644:             it should be very low but not zero otherwise the log go to
                   3645:             infinity.
                   3646:          */
1.183     brouard  3647: /* #ifdef INFINITYORIGINAL */
                   3648: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3649: /* #else */
                   3650: /*       if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                   3651: /*         lli=log(mytinydouble); */
                   3652: /*       else */
                   3653: /*         lli=log(out[s1][s2] - savm[s1][s2]); */
                   3654: /* #endif */
1.226     brouard  3655:          lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3656:          
1.226     brouard  3657:        } else if  ( s2==-1 ) { /* alive */
                   3658:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3659:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3660:          /*survp += out[s1][j]; */
                   3661:          lli= log(survp);
                   3662:        }
                   3663:        else if  (s2==-4) { 
                   3664:          for (j=3,survp=0. ; j<=nlstate; j++)  
                   3665:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3666:          lli= log(survp); 
                   3667:        } 
                   3668:        else if  (s2==-5) { 
                   3669:          for (j=1,survp=0. ; j<=2; j++)  
                   3670:            survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3671:          lli= log(survp); 
                   3672:        } 
                   3673:        else{
                   3674:          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3675:          /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   3676:        } 
                   3677:        /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                   3678:        /*if(lli ==000.0)*/
                   3679:        /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                   3680:        ipmx +=1;
                   3681:        sw += weight[i];
                   3682:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3683:        /* if (lli < log(mytinydouble)){ */
                   3684:        /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                   3685:        /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                   3686:        /* } */
                   3687:       } /* end of wave */
                   3688:     } /* end of individual */
                   3689:   }  else if(mle==2){
                   3690:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3691:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3692:       for(mi=1; mi<= wav[i]-1; mi++){
                   3693:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3694:          for (j=1;j<=nlstate+ndeath;j++){
                   3695:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3696:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3697:          }
                   3698:        for(d=0; d<=dh[mi][i]; d++){
                   3699:          newm=savm;
                   3700:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3701:          cov[2]=agexact;
                   3702:          if(nagesqr==1)
                   3703:            cov[3]= agexact*agexact;
                   3704:          for (kk=1; kk<=cptcovage;kk++) {
                   3705:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3706:          }
                   3707:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3708:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3709:          savm=oldm;
                   3710:          oldm=newm;
                   3711:        } /* end mult */
                   3712:       
                   3713:        s1=s[mw[mi][i]][i];
                   3714:        s2=s[mw[mi+1][i]][i];
                   3715:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3716:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   3717:        ipmx +=1;
                   3718:        sw += weight[i];
                   3719:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3720:       } /* end of wave */
                   3721:     } /* end of individual */
                   3722:   }  else if(mle==3){  /* exponential inter-extrapolation */
                   3723:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3724:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3725:       for(mi=1; mi<= wav[i]-1; mi++){
                   3726:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3727:          for (j=1;j<=nlstate+ndeath;j++){
                   3728:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3729:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3730:          }
                   3731:        for(d=0; d<dh[mi][i]; d++){
                   3732:          newm=savm;
                   3733:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3734:          cov[2]=agexact;
                   3735:          if(nagesqr==1)
                   3736:            cov[3]= agexact*agexact;
                   3737:          for (kk=1; kk<=cptcovage;kk++) {
                   3738:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3739:          }
                   3740:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3741:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3742:          savm=oldm;
                   3743:          oldm=newm;
                   3744:        } /* end mult */
                   3745:       
                   3746:        s1=s[mw[mi][i]][i];
                   3747:        s2=s[mw[mi+1][i]][i];
                   3748:        bbh=(double)bh[mi][i]/(double)stepm; 
                   3749:        lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
                   3750:        ipmx +=1;
                   3751:        sw += weight[i];
                   3752:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3753:       } /* end of wave */
                   3754:     } /* end of individual */
                   3755:   }else if (mle==4){  /* ml=4 no inter-extrapolation */
                   3756:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3757:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3758:       for(mi=1; mi<= wav[i]-1; mi++){
                   3759:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3760:          for (j=1;j<=nlstate+ndeath;j++){
                   3761:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3762:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3763:          }
                   3764:        for(d=0; d<dh[mi][i]; d++){
                   3765:          newm=savm;
                   3766:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3767:          cov[2]=agexact;
                   3768:          if(nagesqr==1)
                   3769:            cov[3]= agexact*agexact;
                   3770:          for (kk=1; kk<=cptcovage;kk++) {
                   3771:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3772:          }
1.126     brouard  3773:        
1.226     brouard  3774:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3775:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3776:          savm=oldm;
                   3777:          oldm=newm;
                   3778:        } /* end mult */
                   3779:       
                   3780:        s1=s[mw[mi][i]][i];
                   3781:        s2=s[mw[mi+1][i]][i];
                   3782:        if( s2 > nlstate){ 
                   3783:          lli=log(out[s1][s2] - savm[s1][s2]);
                   3784:        } else if  ( s2==-1 ) { /* alive */
                   3785:          for (j=1,survp=0. ; j<=nlstate; j++) 
                   3786:            survp += out[s1][j];
                   3787:          lli= log(survp);
                   3788:        }else{
                   3789:          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3790:        }
                   3791:        ipmx +=1;
                   3792:        sw += weight[i];
                   3793:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.126     brouard  3794: /*     printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.226     brouard  3795:       } /* end of wave */
                   3796:     } /* end of individual */
                   3797:   }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
                   3798:     for (i=1,ipmx=0, sw=0.; i<=imx; i++){
                   3799:       for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
                   3800:       for(mi=1; mi<= wav[i]-1; mi++){
                   3801:        for (ii=1;ii<=nlstate+ndeath;ii++)
                   3802:          for (j=1;j<=nlstate+ndeath;j++){
                   3803:            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3804:            savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3805:          }
                   3806:        for(d=0; d<dh[mi][i]; d++){
                   3807:          newm=savm;
                   3808:          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
                   3809:          cov[2]=agexact;
                   3810:          if(nagesqr==1)
                   3811:            cov[3]= agexact*agexact;
                   3812:          for (kk=1; kk<=cptcovage;kk++) {
                   3813:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3814:          }
1.126     brouard  3815:        
1.226     brouard  3816:          out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3817:                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3818:          savm=oldm;
                   3819:          oldm=newm;
                   3820:        } /* end mult */
                   3821:       
                   3822:        s1=s[mw[mi][i]][i];
                   3823:        s2=s[mw[mi+1][i]][i];
                   3824:        lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
                   3825:        ipmx +=1;
                   3826:        sw += weight[i];
                   3827:        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   3828:        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
                   3829:       } /* end of wave */
                   3830:     } /* end of individual */
                   3831:   } /* End of if */
                   3832:   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3833:   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3834:   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3835:   return -l;
1.126     brouard  3836: }
                   3837: 
                   3838: /*************** log-likelihood *************/
                   3839: double funcone( double *x)
                   3840: {
1.228     brouard  3841:   /* Same as func but slower because of a lot of printf and if */
1.126     brouard  3842:   int i, ii, j, k, mi, d, kk;
1.228     brouard  3843:   int ioffset=0;
1.131     brouard  3844:   double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
1.126     brouard  3845:   double **out;
                   3846:   double lli; /* Individual log likelihood */
                   3847:   double llt;
                   3848:   int s1, s2;
1.228     brouard  3849:   int iv=0, iqv=0, itv=0, iqtv=0 ; /* Index of varying covariate, fixed quantitative cov, time varying covariate, quantitative time varying covariate */
                   3850: 
1.126     brouard  3851:   double bbh, survp;
1.187     brouard  3852:   double agexact;
1.214     brouard  3853:   double agebegin, ageend;
1.126     brouard  3854:   /*extern weight */
                   3855:   /* We are differentiating ll according to initial status */
                   3856:   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
                   3857:   /*for(i=1;i<imx;i++) 
                   3858:     printf(" %d\n",s[4][i]);
                   3859:   */
                   3860:   cov[1]=1.;
                   3861: 
                   3862:   for(k=1; k<=nlstate; k++) ll[k]=0.;
1.224     brouard  3863:   ioffset=0;
                   3864:   for (i=1,ipmx=0, sw=0.; i<=imx; i++){
1.243     brouard  3865:     /* ioffset=2+nagesqr+cptcovage; */
                   3866:     ioffset=2+nagesqr;
1.232     brouard  3867:     /* Fixed */
1.224     brouard  3868:     /* for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i]; */
1.232     brouard  3869:     /* for (k=1; k<=ncoveff;k++){ /\* Simple and product fixed Dummy covariates without age* products *\/ */
1.311     brouard  3870:     for (k=1; k<=ncovf;k++){ /* Simple and product fixed covariates without age* products *//* Missing values are set to -1 but should be dropped */
1.232     brouard  3871:       cov[ioffset+TvarFind[k]]=covar[Tvar[TvarFind[k]]][i];/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V1 is fixed (k=6)*/
                   3872: /*    cov[ioffset+TvarFind[1]]=covar[Tvar[TvarFind[1]]][i];  */
                   3873: /*    cov[2+6]=covar[Tvar[6]][i];  */
                   3874: /*    cov[2+6]=covar[2][i]; V2  */
                   3875: /*    cov[TvarFind[2]]=covar[Tvar[TvarFind[2]]][i];  */
                   3876: /*    cov[2+7]=covar[Tvar[7]][i];  */
                   3877: /*    cov[2+7]=covar[7][i]; V7=V1*V2  */
                   3878: /*    cov[TvarFind[3]]=covar[Tvar[TvarFind[3]]][i];  */
                   3879: /*    cov[2+9]=covar[Tvar[9]][i];  */
                   3880: /*    cov[2+9]=covar[1][i]; V1  */
1.225     brouard  3881:     }
1.232     brouard  3882:     /* for (k=1; k<=nqfveff;k++){ /\* Simple and product fixed Quantitative covariates without age* products *\/ */
                   3883:     /*   cov[++ioffset]=coqvar[TvarFQ[k]][i];/\* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, only V2 and V1*V2 is fixed (k=6 and 7?)*\/ */
                   3884:     /* } */
1.231     brouard  3885:     /* for(iqv=1; iqv <= nqfveff; iqv++){ /\* Quantitative fixed covariates *\/ */
                   3886:     /*   cov[++ioffset]=coqvar[Tvar[iqv]][i]; /\* Only V2 k=6 and V1*V2 7 *\/ */
                   3887:     /* } */
1.225     brouard  3888:     
1.233     brouard  3889: 
                   3890:     for(mi=1; mi<= wav[i]-1; mi++){  /* Varying with waves */
1.232     brouard  3891:     /* Wave varying (but not age varying) */
                   3892:       for(k=1; k <= ncovv ; k++){ /* Varying  covariates (single and product but no age )*/
1.242     brouard  3893:        /* cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]][i]; */
                   3894:        cov[ioffset+TvarVind[k]]=cotvar[mw[mi][i]][Tvar[TvarVind[k]]-ncovcol-nqv][i];
                   3895:       }
1.232     brouard  3896:       /* for(itv=1; itv <= ntveff; itv++){ /\* Varying dummy covariates (single??)*\/ */
1.242     brouard  3897:       /* iv= Tvar[Tmodelind[ioffset-2-nagesqr-cptcovage+itv]]-ncovcol-nqv; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3898:       /* cov[ioffset+iv]=cotvar[mw[mi][i]][iv][i]; */
                   3899:       /* k=ioffset-2-nagesqr-cptcovage+itv; /\* position in simple model *\/ */
                   3900:       /* cov[ioffset+itv]=cotvar[mw[mi][i]][TmodelInvind[itv]][i]; */
                   3901:       /* printf(" i=%d,mi=%d,itv=%d,TmodelInvind[itv]=%d,cotvar[mw[mi][i]][TmodelInvind[itv]][i]=%f\n", i, mi, itv, TmodelInvind[itv],cotvar[mw[mi][i]][TmodelInvind[itv]][i]); */
1.232     brouard  3902:       /* for(iqtv=1; iqtv <= nqtveff; iqtv++){ /\* Varying quantitatives covariates *\/ */
1.242     brouard  3903:       /*       iv=TmodelInvQind[iqtv]; /\* Counting the # varying covariate from 1 to ntveff *\/ */
                   3904:       /*       /\* printf(" i=%d,mi=%d,iqtv=%d,TmodelInvQind[iqtv]=%d,cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]=%f\n", i, mi, iqtv, TmodelInvQind[iqtv],cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]); *\/ */
                   3905:       /*       cov[ioffset+ntveff+iqtv]=cotqvar[mw[mi][i]][TmodelInvQind[iqtv]][i]; */
1.232     brouard  3906:       /* } */
1.126     brouard  3907:       for (ii=1;ii<=nlstate+ndeath;ii++)
1.242     brouard  3908:        for (j=1;j<=nlstate+ndeath;j++){
                   3909:          oldm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3910:          savm[ii][j]=(ii==j ? 1.0 : 0.0);
                   3911:        }
1.214     brouard  3912:       
                   3913:       agebegin=agev[mw[mi][i]][i]; /* Age at beginning of effective wave */
                   3914:       ageend=agev[mw[mi][i]][i] + (dh[mi][i])*stepm/YEARM; /* Age at end of effective wave and at the end of transition */
                   3915:       for(d=0; d<dh[mi][i]; d++){  /* Delay between two effective waves */
1.247     brouard  3916:       /* for(d=0; d<=0; d++){  /\* Delay between two effective waves Only one matrix to speed up*\/ */
1.242     brouard  3917:        /*dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   3918:          and mw[mi+1][i]. dh depends on stepm.*/
                   3919:        newm=savm;
1.247     brouard  3920:        agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;  /* Here d is needed */
1.242     brouard  3921:        cov[2]=agexact;
                   3922:        if(nagesqr==1)
                   3923:          cov[3]= agexact*agexact;
                   3924:        for (kk=1; kk<=cptcovage;kk++) {
                   3925:          if(!FixedV[Tvar[Tage[kk]]])
                   3926:            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
                   3927:          else
                   3928:            cov[Tage[kk]+2+nagesqr]=cotvar[mw[mi][i]][Tvar[Tage[kk]]-ncovcol-nqv][i]*agexact;
                   3929:        }
                   3930:        /* printf("i=%d,mi=%d,d=%d,mw[mi][i]=%d\n",i, mi,d,mw[mi][i]); */
                   3931:        /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
                   3932:        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                   3933:                     1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
                   3934:        /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
                   3935:        /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
                   3936:        savm=oldm;
                   3937:        oldm=newm;
1.126     brouard  3938:       } /* end mult */
                   3939:       
                   3940:       s1=s[mw[mi][i]][i];
                   3941:       s2=s[mw[mi+1][i]][i];
1.217     brouard  3942:       /* if(s2==-1){ */
1.268     brouard  3943:       /*       printf(" ERROR s1=%d, s2=%d i=%d \n", s1, s2, i); */
1.217     brouard  3944:       /*       /\* exit(1); *\/ */
                   3945:       /* } */
1.126     brouard  3946:       bbh=(double)bh[mi][i]/(double)stepm; 
                   3947:       /* bias is positive if real duration
                   3948:        * is higher than the multiple of stepm and negative otherwise.
                   3949:        */
                   3950:       if( s2 > nlstate && (mle <5) ){  /* Jackson */
1.242     brouard  3951:        lli=log(out[s1][s2] - savm[s1][s2]);
1.216     brouard  3952:       } else if  ( s2==-1 ) { /* alive */
1.242     brouard  3953:        for (j=1,survp=0. ; j<=nlstate; j++) 
                   3954:          survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   3955:        lli= log(survp);
1.126     brouard  3956:       }else if (mle==1){
1.242     brouard  3957:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
1.126     brouard  3958:       } else if(mle==2){
1.242     brouard  3959:        lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
1.126     brouard  3960:       } else if(mle==3){  /* exponential inter-extrapolation */
1.242     brouard  3961:        lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
1.126     brouard  3962:       } else if (mle==4){  /* mle=4 no inter-extrapolation */
1.242     brouard  3963:        lli=log(out[s1][s2]); /* Original formula */
1.136     brouard  3964:       } else{  /* mle=0 back to 1 */
1.242     brouard  3965:        lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                   3966:        /*lli=log(out[s1][s2]); */ /* Original formula */
1.126     brouard  3967:       } /* End of if */
                   3968:       ipmx +=1;
                   3969:       sw += weight[i];
                   3970:       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
1.132     brouard  3971:       /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
1.126     brouard  3972:       if(globpr){
1.246     brouard  3973:        fprintf(ficresilk,"%09ld %6.1f %6.1f %6d %2d %2d %2d %2d %3d %15.6f %8.4f %8.3f\
1.126     brouard  3974:  %11.6f %11.6f %11.6f ", \
1.242     brouard  3975:                num[i], agebegin, ageend, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
1.268     brouard  3976:                2*weight[i]*lli,(s2==-1? -1: out[s1][s2]),(s2==-1? -1: savm[s1][s2]));
1.242     brouard  3977:        for(k=1,llt=0.,l=0.; k<=nlstate; k++){
                   3978:          llt +=ll[k]*gipmx/gsw;
                   3979:          fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
                   3980:        }
                   3981:        fprintf(ficresilk," %10.6f\n", -llt);
1.126     brouard  3982:       }
1.232     brouard  3983:        } /* end of wave */
                   3984: } /* end of individual */
                   3985: for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
                   3986: /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
                   3987: l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
                   3988: if(globpr==0){ /* First time we count the contributions and weights */
                   3989:        gipmx=ipmx;
                   3990:        gsw=sw;
                   3991: }
                   3992: return -l;
1.126     brouard  3993: }
                   3994: 
                   3995: 
                   3996: /*************** function likelione ***********/
1.292     brouard  3997: void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*func)(double []))
1.126     brouard  3998: {
                   3999:   /* This routine should help understanding what is done with 
                   4000:      the selection of individuals/waves and
                   4001:      to check the exact contribution to the likelihood.
                   4002:      Plotting could be done.
                   4003:    */
                   4004:   int k;
                   4005: 
                   4006:   if(*globpri !=0){ /* Just counts and sums, no printings */
1.201     brouard  4007:     strcpy(fileresilk,"ILK_"); 
1.202     brouard  4008:     strcat(fileresilk,fileresu);
1.126     brouard  4009:     if((ficresilk=fopen(fileresilk,"w"))==NULL) {
                   4010:       printf("Problem with resultfile: %s\n", fileresilk);
                   4011:       fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
                   4012:     }
1.214     brouard  4013:     fprintf(ficresilk, "#individual(line's_record) count ageb ageend s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
                   4014:     fprintf(ficresilk, "#num_i ageb agend i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
1.126     brouard  4015:     /*         i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
                   4016:     for(k=1; k<=nlstate; k++) 
                   4017:       fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
                   4018:     fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
                   4019:   }
                   4020: 
1.292     brouard  4021:   *fretone=(*func)(p);
1.126     brouard  4022:   if(*globpri !=0){
                   4023:     fclose(ficresilk);
1.205     brouard  4024:     if (mle ==0)
                   4025:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
                   4026:     else if(mle >=1)
                   4027:       fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
                   4028:     fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
1.274     brouard  4029:     fprintf(fichtm,"\n<br>Equation of the model: <b>model=1+age+%s</b><br>\n",model); 
1.208     brouard  4030:       
                   4031:     for (k=1; k<= nlstate ; k++) {
1.211     brouard  4032:       fprintf(fichtm,"<br>- Probability p<sub>%dj</sub> by origin %d and destination j. Dot's sizes are related to corresponding weight: <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
1.208     brouard  4033: <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                   4034:     }
1.207     brouard  4035:     fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
1.204     brouard  4036: <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4037:     fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
1.204     brouard  4038: <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
1.207     brouard  4039:     fflush(fichtm);
1.205     brouard  4040:   }
1.126     brouard  4041:   return;
                   4042: }
                   4043: 
                   4044: 
                   4045: /*********** Maximum Likelihood Estimation ***************/
                   4046: 
                   4047: void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                   4048: {
1.165     brouard  4049:   int i,j, iter=0;
1.126     brouard  4050:   double **xi;
                   4051:   double fret;
                   4052:   double fretone; /* Only one call to likelihood */
                   4053:   /*  char filerespow[FILENAMELENGTH];*/
1.162     brouard  4054: 
                   4055: #ifdef NLOPT
                   4056:   int creturn;
                   4057:   nlopt_opt opt;
                   4058:   /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
                   4059:   double *lb;
                   4060:   double minf; /* the minimum objective value, upon return */
                   4061:   double * p1; /* Shifted parameters from 0 instead of 1 */
                   4062:   myfunc_data dinst, *d = &dinst;
                   4063: #endif
                   4064: 
                   4065: 
1.126     brouard  4066:   xi=matrix(1,npar,1,npar);
                   4067:   for (i=1;i<=npar;i++)
                   4068:     for (j=1;j<=npar;j++)
                   4069:       xi[i][j]=(i==j ? 1.0 : 0.0);
                   4070:   printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.201     brouard  4071:   strcpy(filerespow,"POW_"); 
1.126     brouard  4072:   strcat(filerespow,fileres);
                   4073:   if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   4074:     printf("Problem with resultfile: %s\n", filerespow);
                   4075:     fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   4076:   }
                   4077:   fprintf(ficrespow,"# Powell\n# iter -2*LL");
                   4078:   for (i=1;i<=nlstate;i++)
                   4079:     for(j=1;j<=nlstate+ndeath;j++)
                   4080:       if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   4081:   fprintf(ficrespow,"\n");
1.162     brouard  4082: #ifdef POWELL
1.126     brouard  4083:   powell(p,xi,npar,ftol,&iter,&fret,func);
1.162     brouard  4084: #endif
1.126     brouard  4085: 
1.162     brouard  4086: #ifdef NLOPT
                   4087: #ifdef NEWUOA
                   4088:   opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
                   4089: #else
                   4090:   opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
                   4091: #endif
                   4092:   lb=vector(0,npar-1);
                   4093:   for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
                   4094:   nlopt_set_lower_bounds(opt, lb);
                   4095:   nlopt_set_initial_step1(opt, 0.1);
                   4096:   
                   4097:   p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
                   4098:   d->function = func;
                   4099:   printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
                   4100:   nlopt_set_min_objective(opt, myfunc, d);
                   4101:   nlopt_set_xtol_rel(opt, ftol);
                   4102:   if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
                   4103:     printf("nlopt failed! %d\n",creturn); 
                   4104:   }
                   4105:   else {
                   4106:     printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
                   4107:     printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
                   4108:     iter=1; /* not equal */
                   4109:   }
                   4110:   nlopt_destroy(opt);
                   4111: #endif
1.126     brouard  4112:   free_matrix(xi,1,npar,1,npar);
                   4113:   fclose(ficrespow);
1.203     brouard  4114:   printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
                   4115:   fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.180     brouard  4116:   fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
1.126     brouard  4117: 
                   4118: }
                   4119: 
                   4120: /**** Computes Hessian and covariance matrix ***/
1.203     brouard  4121: void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
1.126     brouard  4122: {
                   4123:   double  **a,**y,*x,pd;
1.203     brouard  4124:   /* double **hess; */
1.164     brouard  4125:   int i, j;
1.126     brouard  4126:   int *indx;
                   4127: 
                   4128:   double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
1.203     brouard  4129:   double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
1.126     brouard  4130:   void lubksb(double **a, int npar, int *indx, double b[]) ;
                   4131:   void ludcmp(double **a, int npar, int *indx, double *d) ;
                   4132:   double gompertz(double p[]);
1.203     brouard  4133:   /* hess=matrix(1,npar,1,npar); */
1.126     brouard  4134: 
                   4135:   printf("\nCalculation of the hessian matrix. Wait...\n");
                   4136:   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
                   4137:   for (i=1;i<=npar;i++){
1.203     brouard  4138:     printf("%d-",i);fflush(stdout);
                   4139:     fprintf(ficlog,"%d-",i);fflush(ficlog);
1.126     brouard  4140:    
                   4141:      hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
                   4142:     
                   4143:     /*  printf(" %f ",p[i]);
                   4144:        printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
                   4145:   }
                   4146:   
                   4147:   for (i=1;i<=npar;i++) {
                   4148:     for (j=1;j<=npar;j++)  {
                   4149:       if (j>i) { 
1.203     brouard  4150:        printf(".%d-%d",i,j);fflush(stdout);
                   4151:        fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
                   4152:        hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
1.126     brouard  4153:        
                   4154:        hess[j][i]=hess[i][j];    
                   4155:        /*printf(" %lf ",hess[i][j]);*/
                   4156:       }
                   4157:     }
                   4158:   }
                   4159:   printf("\n");
                   4160:   fprintf(ficlog,"\n");
                   4161: 
                   4162:   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4163:   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
                   4164:   
                   4165:   a=matrix(1,npar,1,npar);
                   4166:   y=matrix(1,npar,1,npar);
                   4167:   x=vector(1,npar);
                   4168:   indx=ivector(1,npar);
                   4169:   for (i=1;i<=npar;i++)
                   4170:     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   4171:   ludcmp(a,npar,indx,&pd);
                   4172: 
                   4173:   for (j=1;j<=npar;j++) {
                   4174:     for (i=1;i<=npar;i++) x[i]=0;
                   4175:     x[j]=1;
                   4176:     lubksb(a,npar,indx,x);
                   4177:     for (i=1;i<=npar;i++){ 
                   4178:       matcov[i][j]=x[i];
                   4179:     }
                   4180:   }
                   4181: 
                   4182:   printf("\n#Hessian matrix#\n");
                   4183:   fprintf(ficlog,"\n#Hessian matrix#\n");
                   4184:   for (i=1;i<=npar;i++) { 
                   4185:     for (j=1;j<=npar;j++) { 
1.203     brouard  4186:       printf("%.6e ",hess[i][j]);
                   4187:       fprintf(ficlog,"%.6e ",hess[i][j]);
1.126     brouard  4188:     }
                   4189:     printf("\n");
                   4190:     fprintf(ficlog,"\n");
                   4191:   }
                   4192: 
1.203     brouard  4193:   /* printf("\n#Covariance matrix#\n"); */
                   4194:   /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
                   4195:   /* for (i=1;i<=npar;i++) {  */
                   4196:   /*   for (j=1;j<=npar;j++) {  */
                   4197:   /*     printf("%.6e ",matcov[i][j]); */
                   4198:   /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
                   4199:   /*   } */
                   4200:   /*   printf("\n"); */
                   4201:   /*   fprintf(ficlog,"\n"); */
                   4202:   /* } */
                   4203: 
1.126     brouard  4204:   /* Recompute Inverse */
1.203     brouard  4205:   /* for (i=1;i<=npar;i++) */
                   4206:   /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
                   4207:   /* ludcmp(a,npar,indx,&pd); */
                   4208: 
                   4209:   /*  printf("\n#Hessian matrix recomputed#\n"); */
                   4210: 
                   4211:   /* for (j=1;j<=npar;j++) { */
                   4212:   /*   for (i=1;i<=npar;i++) x[i]=0; */
                   4213:   /*   x[j]=1; */
                   4214:   /*   lubksb(a,npar,indx,x); */
                   4215:   /*   for (i=1;i<=npar;i++){  */
                   4216:   /*     y[i][j]=x[i]; */
                   4217:   /*     printf("%.3e ",y[i][j]); */
                   4218:   /*     fprintf(ficlog,"%.3e ",y[i][j]); */
                   4219:   /*   } */
                   4220:   /*   printf("\n"); */
                   4221:   /*   fprintf(ficlog,"\n"); */
                   4222:   /* } */
                   4223: 
                   4224:   /* Verifying the inverse matrix */
                   4225: #ifdef DEBUGHESS
                   4226:   y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
1.126     brouard  4227: 
1.203     brouard  4228:    printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
                   4229:    fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
1.126     brouard  4230: 
                   4231:   for (j=1;j<=npar;j++) {
                   4232:     for (i=1;i<=npar;i++){ 
1.203     brouard  4233:       printf("%.2f ",y[i][j]);
                   4234:       fprintf(ficlog,"%.2f ",y[i][j]);
1.126     brouard  4235:     }
                   4236:     printf("\n");
                   4237:     fprintf(ficlog,"\n");
                   4238:   }
1.203     brouard  4239: #endif
1.126     brouard  4240: 
                   4241:   free_matrix(a,1,npar,1,npar);
                   4242:   free_matrix(y,1,npar,1,npar);
                   4243:   free_vector(x,1,npar);
                   4244:   free_ivector(indx,1,npar);
1.203     brouard  4245:   /* free_matrix(hess,1,npar,1,npar); */
1.126     brouard  4246: 
                   4247: 
                   4248: }
                   4249: 
                   4250: /*************** hessian matrix ****************/
                   4251: double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
1.203     brouard  4252: { /* Around values of x, computes the function func and returns the scales delti and hessian */
1.126     brouard  4253:   int i;
                   4254:   int l=1, lmax=20;
1.203     brouard  4255:   double k1,k2, res, fx;
1.132     brouard  4256:   double p2[MAXPARM+1]; /* identical to x */
1.126     brouard  4257:   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
                   4258:   int k=0,kmax=10;
                   4259:   double l1;
                   4260: 
                   4261:   fx=func(x);
                   4262:   for (i=1;i<=npar;i++) p2[i]=x[i];
1.145     brouard  4263:   for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
1.126     brouard  4264:     l1=pow(10,l);
                   4265:     delts=delt;
                   4266:     for(k=1 ; k <kmax; k=k+1){
                   4267:       delt = delta*(l1*k);
                   4268:       p2[theta]=x[theta] +delt;
1.145     brouard  4269:       k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
1.126     brouard  4270:       p2[theta]=x[theta]-delt;
                   4271:       k2=func(p2)-fx;
                   4272:       /*res= (k1-2.0*fx+k2)/delt/delt; */
1.203     brouard  4273:       res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
1.126     brouard  4274:       
1.203     brouard  4275: #ifdef DEBUGHESSII
1.126     brouard  4276:       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4277:       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
                   4278: #endif
                   4279:       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   4280:       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                   4281:        k=kmax;
                   4282:       }
                   4283:       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
1.164     brouard  4284:        k=kmax; l=lmax*10;
1.126     brouard  4285:       }
                   4286:       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   4287:        delts=delt;
                   4288:       }
1.203     brouard  4289:     } /* End loop k */
1.126     brouard  4290:   }
                   4291:   delti[theta]=delts;
                   4292:   return res; 
                   4293:   
                   4294: }
                   4295: 
1.203     brouard  4296: double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
1.126     brouard  4297: {
                   4298:   int i;
1.164     brouard  4299:   int l=1, lmax=20;
1.126     brouard  4300:   double k1,k2,k3,k4,res,fx;
1.132     brouard  4301:   double p2[MAXPARM+1];
1.203     brouard  4302:   int k, kmax=1;
                   4303:   double v1, v2, cv12, lc1, lc2;
1.208     brouard  4304: 
                   4305:   int firstime=0;
1.203     brouard  4306:   
1.126     brouard  4307:   fx=func(x);
1.203     brouard  4308:   for (k=1; k<=kmax; k=k+10) {
1.126     brouard  4309:     for (i=1;i<=npar;i++) p2[i]=x[i];
1.203     brouard  4310:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4311:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4312:     k1=func(p2)-fx;
                   4313:   
1.203     brouard  4314:     p2[thetai]=x[thetai]+delti[thetai]*k;
                   4315:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4316:     k2=func(p2)-fx;
                   4317:   
1.203     brouard  4318:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4319:     p2[thetaj]=x[thetaj]+delti[thetaj]*k;
1.126     brouard  4320:     k3=func(p2)-fx;
                   4321:   
1.203     brouard  4322:     p2[thetai]=x[thetai]-delti[thetai]*k;
                   4323:     p2[thetaj]=x[thetaj]-delti[thetaj]*k;
1.126     brouard  4324:     k4=func(p2)-fx;
1.203     brouard  4325:     res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
                   4326:     if(k1*k2*k3*k4 <0.){
1.208     brouard  4327:       firstime=1;
1.203     brouard  4328:       kmax=kmax+10;
1.208     brouard  4329:     }
                   4330:     if(kmax >=10 || firstime ==1){
1.246     brouard  4331:       printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
                   4332:       fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; you could increase ftol=%.2e\n",thetai,thetaj, ftol);
1.203     brouard  4333:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4334:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4335:     }
                   4336: #ifdef DEBUGHESSIJ
                   4337:     v1=hess[thetai][thetai];
                   4338:     v2=hess[thetaj][thetaj];
                   4339:     cv12=res;
                   4340:     /* Computing eigen value of Hessian matrix */
                   4341:     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4342:     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   4343:     if ((lc2 <0) || (lc1 <0) ){
                   4344:       printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4345:       fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
                   4346:       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4347:       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
                   4348:     }
1.126     brouard  4349: #endif
                   4350:   }
                   4351:   return res;
                   4352: }
                   4353: 
1.203     brouard  4354:     /* Not done yet: Was supposed to fix if not exactly at the maximum */
                   4355: /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
                   4356: /* { */
                   4357: /*   int i; */
                   4358: /*   int l=1, lmax=20; */
                   4359: /*   double k1,k2,k3,k4,res,fx; */
                   4360: /*   double p2[MAXPARM+1]; */
                   4361: /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
                   4362: /*   int k=0,kmax=10; */
                   4363: /*   double l1; */
                   4364:   
                   4365: /*   fx=func(x); */
                   4366: /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
                   4367: /*     l1=pow(10,l); */
                   4368: /*     delts=delt; */
                   4369: /*     for(k=1 ; k <kmax; k=k+1){ */
                   4370: /*       delt = delti*(l1*k); */
                   4371: /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
                   4372: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4373: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4374: /*       k1=func(p2)-fx; */
                   4375:       
                   4376: /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
                   4377: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4378: /*       k2=func(p2)-fx; */
                   4379:       
                   4380: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4381: /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
                   4382: /*       k3=func(p2)-fx; */
                   4383:       
                   4384: /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
                   4385: /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
                   4386: /*       k4=func(p2)-fx; */
                   4387: /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
                   4388: /* #ifdef DEBUGHESSIJ */
                   4389: /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4390: /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
                   4391: /* #endif */
                   4392: /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
                   4393: /*     k=kmax; */
                   4394: /*       } */
                   4395: /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
                   4396: /*     k=kmax; l=lmax*10; */
                   4397: /*       } */
                   4398: /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
                   4399: /*     delts=delt; */
                   4400: /*       } */
                   4401: /*     } /\* End loop k *\/ */
                   4402: /*   } */
                   4403: /*   delti[theta]=delts; */
                   4404: /*   return res;  */
                   4405: /* } */
                   4406: 
                   4407: 
1.126     brouard  4408: /************** Inverse of matrix **************/
                   4409: void ludcmp(double **a, int n, int *indx, double *d) 
                   4410: { 
                   4411:   int i,imax,j,k; 
                   4412:   double big,dum,sum,temp; 
                   4413:   double *vv; 
                   4414:  
                   4415:   vv=vector(1,n); 
                   4416:   *d=1.0; 
                   4417:   for (i=1;i<=n;i++) { 
                   4418:     big=0.0; 
                   4419:     for (j=1;j<=n;j++) 
                   4420:       if ((temp=fabs(a[i][j])) > big) big=temp; 
1.256     brouard  4421:     if (big == 0.0){
                   4422:       printf(" Singular Hessian matrix at row %d:\n",i);
                   4423:       for (j=1;j<=n;j++) {
                   4424:        printf(" a[%d][%d]=%f,",i,j,a[i][j]);
                   4425:        fprintf(ficlog," a[%d][%d]=%f,",i,j,a[i][j]);
                   4426:       }
                   4427:       fflush(ficlog);
                   4428:       fclose(ficlog);
                   4429:       nrerror("Singular matrix in routine ludcmp"); 
                   4430:     }
1.126     brouard  4431:     vv[i]=1.0/big; 
                   4432:   } 
                   4433:   for (j=1;j<=n;j++) { 
                   4434:     for (i=1;i<j;i++) { 
                   4435:       sum=a[i][j]; 
                   4436:       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
                   4437:       a[i][j]=sum; 
                   4438:     } 
                   4439:     big=0.0; 
                   4440:     for (i=j;i<=n;i++) { 
                   4441:       sum=a[i][j]; 
                   4442:       for (k=1;k<j;k++) 
                   4443:        sum -= a[i][k]*a[k][j]; 
                   4444:       a[i][j]=sum; 
                   4445:       if ( (dum=vv[i]*fabs(sum)) >= big) { 
                   4446:        big=dum; 
                   4447:        imax=i; 
                   4448:       } 
                   4449:     } 
                   4450:     if (j != imax) { 
                   4451:       for (k=1;k<=n;k++) { 
                   4452:        dum=a[imax][k]; 
                   4453:        a[imax][k]=a[j][k]; 
                   4454:        a[j][k]=dum; 
                   4455:       } 
                   4456:       *d = -(*d); 
                   4457:       vv[imax]=vv[j]; 
                   4458:     } 
                   4459:     indx[j]=imax; 
                   4460:     if (a[j][j] == 0.0) a[j][j]=TINY; 
                   4461:     if (j != n) { 
                   4462:       dum=1.0/(a[j][j]); 
                   4463:       for (i=j+1;i<=n;i++) a[i][j] *= dum; 
                   4464:     } 
                   4465:   } 
                   4466:   free_vector(vv,1,n);  /* Doesn't work */
                   4467: ;
                   4468: } 
                   4469: 
                   4470: void lubksb(double **a, int n, int *indx, double b[]) 
                   4471: { 
                   4472:   int i,ii=0,ip,j; 
                   4473:   double sum; 
                   4474:  
                   4475:   for (i=1;i<=n;i++) { 
                   4476:     ip=indx[i]; 
                   4477:     sum=b[ip]; 
                   4478:     b[ip]=b[i]; 
                   4479:     if (ii) 
                   4480:       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
                   4481:     else if (sum) ii=i; 
                   4482:     b[i]=sum; 
                   4483:   } 
                   4484:   for (i=n;i>=1;i--) { 
                   4485:     sum=b[i]; 
                   4486:     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
                   4487:     b[i]=sum/a[i][i]; 
                   4488:   } 
                   4489: } 
                   4490: 
                   4491: void pstamp(FILE *fichier)
                   4492: {
1.196     brouard  4493:   fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
1.126     brouard  4494: }
                   4495: 
1.297     brouard  4496: void date2dmy(double date,double *day, double *month, double *year){
                   4497:   double yp=0., yp1=0., yp2=0.;
                   4498:   
                   4499:   yp1=modf(date,&yp);/* extracts integral of date in yp  and
                   4500:                        fractional in yp1 */
                   4501:   *year=yp;
                   4502:   yp2=modf((yp1*12),&yp);
                   4503:   *month=yp;
                   4504:   yp1=modf((yp2*30.5),&yp);
                   4505:   *day=yp;
                   4506:   if(*day==0) *day=1;
                   4507:   if(*month==0) *month=1;
                   4508: }
                   4509: 
1.253     brouard  4510: 
                   4511: 
1.126     brouard  4512: /************ Frequencies ********************/
1.251     brouard  4513: void  freqsummary(char fileres[], double p[], double pstart[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, \
1.226     brouard  4514:                  int *Tvaraff, int *invalidvarcomb, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[], \
                   4515:                  int firstpass,  int lastpass, int stepm, int weightopt, char model[])
1.250     brouard  4516: {  /* Some frequencies as well as proposing some starting values */
1.226     brouard  4517:   
1.265     brouard  4518:   int i, m, jk, j1, bool, z1,j, nj, nl, k, iv, jj=0, s1=1, s2=1;
1.226     brouard  4519:   int iind=0, iage=0;
                   4520:   int mi; /* Effective wave */
                   4521:   int first;
                   4522:   double ***freq; /* Frequencies */
1.268     brouard  4523:   double *x, *y, a=0.,b=0.,r=1., sa=0., sb=0.; /* for regression, y=b+m*x and r is the correlation coefficient */
                   4524:   int no=0, linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb);
1.284     brouard  4525:   double *meanq, *stdq, *idq;
1.226     brouard  4526:   double **meanqt;
                   4527:   double *pp, **prop, *posprop, *pospropt;
                   4528:   double pos=0., posproptt=0., pospropta=0., k2, dateintsum=0,k2cpt=0;
                   4529:   char fileresp[FILENAMELENGTH], fileresphtm[FILENAMELENGTH], fileresphtmfr[FILENAMELENGTH];
                   4530:   double agebegin, ageend;
                   4531:     
                   4532:   pp=vector(1,nlstate);
1.251     brouard  4533:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.226     brouard  4534:   posprop=vector(1,nlstate); /* Counting the number of transition starting from a live state per age */ 
                   4535:   pospropt=vector(1,nlstate); /* Counting the number of transition starting from a live state */ 
                   4536:   /* prop=matrix(1,nlstate,iagemin,iagemax+3); */
                   4537:   meanq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.284     brouard  4538:   stdq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.283     brouard  4539:   idq=vector(1,nqfveff); /* Number of Quantitative Fixed Variables Effective */
1.226     brouard  4540:   meanqt=matrix(1,lastpass,1,nqtveff);
                   4541:   strcpy(fileresp,"P_");
                   4542:   strcat(fileresp,fileresu);
                   4543:   /*strcat(fileresphtm,fileresu);*/
                   4544:   if((ficresp=fopen(fileresp,"w"))==NULL) {
                   4545:     printf("Problem with prevalence resultfile: %s\n", fileresp);
                   4546:     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
                   4547:     exit(0);
                   4548:   }
1.240     brouard  4549:   
1.226     brouard  4550:   strcpy(fileresphtm,subdirfext(optionfilefiname,"PHTM_",".htm"));
                   4551:   if((ficresphtm=fopen(fileresphtm,"w"))==NULL) {
                   4552:     printf("Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4553:     fprintf(ficlog,"Problem with prevalence HTM resultfile '%s' with errno='%s'\n",fileresphtm,strerror(errno));
                   4554:     fflush(ficlog);
                   4555:     exit(70); 
                   4556:   }
                   4557:   else{
                   4558:     fprintf(ficresphtm,"<html><head>\n<title>IMaCh PHTM_ %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4559: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4560: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4561:            fileresphtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4562:   }
1.237     brouard  4563:   fprintf(ficresphtm,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies and prevalence by age at begin of transition and dummy covariate value at beginning of transition</h4>\n",fileresphtm, fileresphtm);
1.240     brouard  4564:   
1.226     brouard  4565:   strcpy(fileresphtmfr,subdirfext(optionfilefiname,"PHTMFR_",".htm"));
                   4566:   if((ficresphtmfr=fopen(fileresphtmfr,"w"))==NULL) {
                   4567:     printf("Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4568:     fprintf(ficlog,"Problem with frequency table HTM resultfile '%s' with errno='%s'\n",fileresphtmfr,strerror(errno));
                   4569:     fflush(ficlog);
                   4570:     exit(70); 
1.240     brouard  4571:   } else{
1.226     brouard  4572:     fprintf(ficresphtmfr,"<html><head>\n<title>IMaCh PHTM_Frequency table %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
1.240     brouard  4573: <hr size=\"2\" color=\"#EC5E5E\"> \n                                   \
1.214     brouard  4574: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.226     brouard  4575:            fileresphtmfr,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   4576:   }
1.240     brouard  4577:   fprintf(ficresphtmfr,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Frequencies of all effective transitions of the model, by age at begin of transition, and covariate value at the begin of transition (if the covariate is a varying covariate) </h4>Unknown status is -1<br/>\n",fileresphtmfr, fileresphtmfr);
                   4578:   
1.253     brouard  4579:   y= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
                   4580:   x= vector(iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.251     brouard  4581:   freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.226     brouard  4582:   j1=0;
1.126     brouard  4583:   
1.227     brouard  4584:   /* j=ncoveff;  /\* Only fixed dummy covariates *\/ */
                   4585:   j=cptcoveff;  /* Only dummy covariates of the model */
1.226     brouard  4586:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.240     brouard  4587:   
                   4588:   
1.226     brouard  4589:   /* Detects if a combination j1 is empty: for a multinomial variable like 3 education levels:
                   4590:      reference=low_education V1=0,V2=0
                   4591:      med_educ                V1=1 V2=0, 
                   4592:      high_educ               V1=0 V2=1
                   4593:      Then V1=1 and V2=1 is a noisy combination that we want to exclude for the list 2**cptcoveff 
                   4594:   */
1.249     brouard  4595:   dateintsum=0;
                   4596:   k2cpt=0;
                   4597: 
1.253     brouard  4598:   if(cptcoveff == 0 )
1.265     brouard  4599:     nl=1;  /* Constant and age model only */
1.253     brouard  4600:   else
                   4601:     nl=2;
1.265     brouard  4602: 
                   4603:   /* if a constant only model, one pass to compute frequency tables and to write it on ficresp */
                   4604:   /* Loop on nj=1 or 2 if dummy covariates j!=0
                   4605:    *   Loop on j1(1 to 2**cptcoveff) covariate combination
                   4606:    *     freq[s1][s2][iage] =0.
                   4607:    *     Loop on iind
                   4608:    *       ++freq[s1][s2][iage] weighted
                   4609:    *     end iind
                   4610:    *     if covariate and j!0
                   4611:    *       headers Variable on one line
                   4612:    *     endif cov j!=0
                   4613:    *     header of frequency table by age
                   4614:    *     Loop on age
                   4615:    *       pp[s1]+=freq[s1][s2][iage] weighted
                   4616:    *       pos+=freq[s1][s2][iage] weighted
                   4617:    *       Loop on s1 initial state
                   4618:    *         fprintf(ficresp
                   4619:    *       end s1
                   4620:    *     end age
                   4621:    *     if j!=0 computes starting values
                   4622:    *     end compute starting values
                   4623:    *   end j1
                   4624:    * end nl 
                   4625:    */
1.253     brouard  4626:   for (nj = 1; nj <= nl; nj++){   /* nj= 1 constant model, nl number of loops. */
                   4627:     if(nj==1)
                   4628:       j=0;  /* First pass for the constant */
1.265     brouard  4629:     else{
1.253     brouard  4630:       j=cptcoveff; /* Other passes for the covariate values */
1.265     brouard  4631:     }
1.251     brouard  4632:     first=1;
1.265     brouard  4633:     for (j1 = 1; j1 <= (int) pow(2,j); j1++){ /* Loop on all covariates combination of the model, excluding quantitatives, V4=0, V3=0 for example, fixed or varying covariates */
1.251     brouard  4634:       posproptt=0.;
                   4635:       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
                   4636:        scanf("%d", i);*/
                   4637:       for (i=-5; i<=nlstate+ndeath; i++)  
1.265     brouard  4638:        for (s2=-5; s2<=nlstate+ndeath; s2++)  
1.251     brouard  4639:          for(m=iagemin; m <= iagemax+3; m++)
1.265     brouard  4640:            freq[i][s2][m]=0;
1.251     brouard  4641:       
                   4642:       for (i=1; i<=nlstate; i++)  {
1.240     brouard  4643:        for(m=iagemin; m <= iagemax+3; m++)
1.251     brouard  4644:          prop[i][m]=0;
                   4645:        posprop[i]=0;
                   4646:        pospropt[i]=0;
                   4647:       }
1.283     brouard  4648:       for (z1=1; z1<= nqfveff; z1++) { /* zeroing for each combination j1 as well as for the total */
1.284     brouard  4649:         idq[z1]=0.;
                   4650:         meanq[z1]=0.;
                   4651:         stdq[z1]=0.;
1.283     brouard  4652:       }
                   4653:       /* for (z1=1; z1<= nqtveff; z1++) { */
1.251     brouard  4654:       /*   for(m=1;m<=lastpass;m++){ */
1.283     brouard  4655:       /*         meanqt[m][z1]=0.; */
                   4656:       /*       } */
                   4657:       /* }       */
1.251     brouard  4658:       /* dateintsum=0; */
                   4659:       /* k2cpt=0; */
                   4660:       
1.265     brouard  4661:       /* For that combination of covariates j1 (V4=1 V3=0 for example), we count and print the frequencies in one pass */
1.251     brouard  4662:       for (iind=1; iind<=imx; iind++) { /* For each individual iind */
                   4663:        bool=1;
                   4664:        if(j !=0){
                   4665:          if(anyvaryingduminmodel==0){ /* If All fixed covariates */
                   4666:            if (cptcoveff >0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
                   4667:              for (z1=1; z1<=cptcoveff; z1++) { /* loops on covariates in the model */
                   4668:                /* if(Tvaraff[z1] ==-20){ */
                   4669:                /*       /\* sumnew+=cotvar[mw[mi][iind]][z1][iind]; *\/ */
                   4670:                /* }else  if(Tvaraff[z1] ==-10){ */
                   4671:                /*       /\* sumnew+=coqvar[z1][iind]; *\/ */
                   4672:                /* }else  */
                   4673:                if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){ /* for combination j1 of covariates */
1.265     brouard  4674:                  /* Tests if the value of the covariate z1 for this individual iind responded to combination j1 (V4=1 V3=0) */
1.251     brouard  4675:                  bool=0; /* bool should be equal to 1 to be selected, one covariate value failed */
                   4676:                  /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
                   4677:                     bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
                   4678:                     j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
                   4679:                  /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
                   4680:                } /* Onlyf fixed */
                   4681:              } /* end z1 */
                   4682:            } /* cptcovn > 0 */
                   4683:          } /* end any */
                   4684:        }/* end j==0 */
1.265     brouard  4685:        if (bool==1){ /* We selected an individual iind satisfying combination j1 (V4=1 V3=0) or all fixed covariates */
1.251     brouard  4686:          /* for(m=firstpass; m<=lastpass; m++){ */
1.284     brouard  4687:          for(mi=1; mi<wav[iind];mi++){ /* For each wave */
1.251     brouard  4688:            m=mw[mi][iind];
                   4689:            if(j!=0){
                   4690:              if(anyvaryingduminmodel==1){ /* Some are varying covariates */
                   4691:                for (z1=1; z1<=cptcoveff; z1++) {
                   4692:                  if( Fixed[Tmodelind[z1]]==1){
                   4693:                    iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   4694:                    if (cotvar[m][iv][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality. If covariate's 
                   4695:                                                                                      value is -1, we don't select. It differs from the 
                   4696:                                                                                      constant and age model which counts them. */
                   4697:                      bool=0; /* not selected */
                   4698:                  }else if( Fixed[Tmodelind[z1]]== 0) { /* fixed */
                   4699:                    if (covar[Tvaraff[z1]][iind]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   4700:                      bool=0;
                   4701:                    }
                   4702:                  }
                   4703:                }
                   4704:              }/* Some are varying covariates, we tried to speed up if all fixed covariates in the model, avoiding waves loop  */
                   4705:            } /* end j==0 */
                   4706:            /* bool =0 we keep that guy which corresponds to the combination of dummy values */
1.284     brouard  4707:            if(bool==1){ /*Selected */
1.251     brouard  4708:              /* dh[m][iind] or dh[mw[mi][iind]][iind] is the delay between two effective (mi) waves m=mw[mi][iind]
                   4709:                 and mw[mi+1][iind]. dh depends on stepm. */
                   4710:              agebegin=agev[m][iind]; /* Age at beginning of wave before transition*/
                   4711:              ageend=agev[m][iind]+(dh[m][iind])*stepm/YEARM; /* Age at end of wave and transition */
                   4712:              if(m >=firstpass && m <=lastpass){
                   4713:                k2=anint[m][iind]+(mint[m][iind]/12.);
                   4714:                /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
                   4715:                if(agev[m][iind]==0) agev[m][iind]=iagemax+1;  /* All ages equal to 0 are in iagemax+1 */
                   4716:                if(agev[m][iind]==1) agev[m][iind]=iagemax+2;  /* All ages equal to 1 are in iagemax+2 */
                   4717:                if (s[m][iind]>0 && s[m][iind]<=nlstate)  /* If status at wave m is known and a live state */
                   4718:                  prop[s[m][iind]][(int)agev[m][iind]] += weight[iind];  /* At age of beginning of transition, where status is known */
                   4719:                if (m<lastpass) {
                   4720:                  /* if(s[m][iind]==4 && s[m+1][iind]==4) */
                   4721:                  /*   printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind]); */
                   4722:                  if(s[m][iind]==-1)
                   4723:                    printf(" num=%ld m=%d, iind=%d s1=%d s2=%d agev at m=%d agebegin=%.2f ageend=%.2f, agemed=%d\n", num[iind], m, iind,s[m][iind],s[m+1][iind], (int)agev[m][iind],agebegin, ageend, (int)((agebegin+ageend)/2.));
                   4724:                  freq[s[m][iind]][s[m+1][iind]][(int)agev[m][iind]] += weight[iind]; /* At age of beginning of transition, where status is known */
1.311     brouard  4725:                  for (z1=1; z1<= nqfveff; z1++) { /* Quantitative variables, calculating mean on known values only */
                   4726:                    if(!isnan(covar[ncovcol+z1][iind])){
                   4727:                        idq[z1]=idq[z1]+weight[iind];
                   4728:                        meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /* Computes mean of quantitative with selected filter */
                   4729:                        /* stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; *//*error*/
                   4730:                        stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]; /* *weight[iind];*/  /* Computes mean of quantitative with selected filter */
                   4731:                    }
1.284     brouard  4732:                  }
1.251     brouard  4733:                  /* if((int)agev[m][iind] == 55) */
                   4734:                  /*   printf("j=%d, j1=%d Age %d, iind=%d, num=%09ld m=%d\n",j,j1,(int)agev[m][iind],iind, num[iind],m); */
                   4735:                  /* freq[s[m][iind]][s[m+1][iind]][(int)((agebegin+ageend)/2.)] += weight[iind]; */
                   4736:                  freq[s[m][iind]][s[m+1][iind]][iagemax+3] += weight[iind]; /* Total is in iagemax+3 *//* At age of beginning of transition, where status is known */
1.234     brouard  4737:                }
1.251     brouard  4738:              } /* end if between passes */  
                   4739:              if ((agev[m][iind]>1) && (agev[m][iind]< (iagemax+3)) && (anint[m][iind]!=9999) && (mint[m][iind]!=99) && (j==0)) {
                   4740:                dateintsum=dateintsum+k2; /* on all covariates ?*/
                   4741:                k2cpt++;
                   4742:                /* printf("iind=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",iind, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
1.234     brouard  4743:              }
1.251     brouard  4744:            }else{
                   4745:              bool=1;
                   4746:            }/* end bool 2 */
                   4747:          } /* end m */
1.284     brouard  4748:          /* for (z1=1; z1<= nqfveff; z1++) { /\* Quantitative variables, calculating mean *\/ */
                   4749:          /*   idq[z1]=idq[z1]+weight[iind]; */
                   4750:          /*   meanq[z1]+=covar[ncovcol+z1][iind]*weight[iind];  /\* Computes mean of quantitative with selected filter *\/ */
                   4751:          /*   stdq[z1]+=covar[ncovcol+z1][iind]*covar[ncovcol+z1][iind]*weight[iind]*weight[iind]; /\* *weight[iind];*\/  /\* Computes mean of quantitative with selected filter *\/ */
                   4752:          /* } */
1.251     brouard  4753:        } /* end bool */
                   4754:       } /* end iind = 1 to imx */
                   4755:       /* prop[s][age] is feeded for any initial and valid live state as well as
                   4756:         freq[s1][s2][age] at single age of beginning the transition, for a combination j1 */
                   4757:       
                   4758:       
                   4759:       /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
1.265     brouard  4760:       if(cptcoveff==0 && nj==1) /* no covariate and first pass */
                   4761:         pstamp(ficresp);
1.251     brouard  4762:       if  (cptcoveff>0 && j!=0){
1.265     brouard  4763:         pstamp(ficresp);
1.251     brouard  4764:        printf( "\n#********** Variable "); 
                   4765:        fprintf(ficresp, "\n#********** Variable "); 
                   4766:        fprintf(ficresphtm, "\n<br/><br/><h3>********** Variable "); 
                   4767:        fprintf(ficresphtmfr, "\n<br/><br/><h3>********** Variable "); 
                   4768:        fprintf(ficlog, "\n#********** Variable "); 
                   4769:        for (z1=1; z1<=cptcoveff; z1++){
                   4770:          if(!FixedV[Tvaraff[z1]]){
                   4771:            printf( "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4772:            fprintf(ficresp, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4773:            fprintf(ficresphtm, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4774:            fprintf(ficresphtmfr, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4775:            fprintf(ficlog, "V%d(fixed)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.250     brouard  4776:          }else{
1.251     brouard  4777:            printf( "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4778:            fprintf(ficresp, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4779:            fprintf(ficresphtm, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4780:            fprintf(ficresphtmfr, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4781:            fprintf(ficlog, "V%d(varying)=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4782:          }
                   4783:        }
                   4784:        printf( "**********\n#");
                   4785:        fprintf(ficresp, "**********\n#");
                   4786:        fprintf(ficresphtm, "**********</h3>\n");
                   4787:        fprintf(ficresphtmfr, "**********</h3>\n");
                   4788:        fprintf(ficlog, "**********\n");
                   4789:       }
1.284     brouard  4790:       /*
                   4791:        Printing means of quantitative variables if any
                   4792:       */
                   4793:       for (z1=1; z1<= nqfveff; z1++) {
1.311     brouard  4794:        fprintf(ficlog,"Mean of fixed quantitative variable V%d on %.3g (weighted) individuals sum=%f", ncovcol+z1, idq[z1], meanq[z1]);
1.312     brouard  4795:        fprintf(ficlog,", mean=%.3g\n",meanq[z1]/idq[z1]);
1.284     brouard  4796:        if(weightopt==1){
                   4797:          printf(" Weighted mean and standard deviation of");
                   4798:          fprintf(ficlog," Weighted mean and standard deviation of");
                   4799:          fprintf(ficresphtmfr," Weighted mean and standard deviation of");
                   4800:        }
1.311     brouard  4801:        /* mu = \frac{w x}{\sum w}
                   4802:            var = \frac{\sum w (x-mu)^2}{\sum w} = \frac{w x^2}{\sum w} - mu^2 
                   4803:        */
                   4804:        printf(" fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   4805:        fprintf(ficlog," fixed quantitative variable V%d on  %.3g (weighted) representatives of the population : %8.5g (%8.5g)\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
                   4806:        fprintf(ficresphtmfr," fixed quantitative variable V%d on %.3g (weighted) representatives of the population : %8.5g (%8.5g)<p>\n", ncovcol+z1, idq[z1],meanq[z1]/idq[z1], sqrt(stdq[z1]/idq[z1]-meanq[z1]*meanq[z1]/idq[z1]/idq[z1]));
1.284     brouard  4807:       }
                   4808:       /* for (z1=1; z1<= nqtveff; z1++) { */
                   4809:       /*       for(m=1;m<=lastpass;m++){ */
                   4810:       /*         fprintf(ficresphtmfr,"V quantitative id %d, pass id=%d, mean=%f<p>\n", z1, m, meanqt[m][z1]); */
                   4811:       /*   } */
                   4812:       /* } */
1.283     brouard  4813: 
1.251     brouard  4814:       fprintf(ficresphtm,"<table style=\"text-align:center; border: 1px solid\">");
1.265     brouard  4815:       if((cptcoveff==0 && nj==1)|| nj==2 ) /* no covariate and first pass */
                   4816:         fprintf(ficresp, " Age");
                   4817:       if(nj==2) for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " V%d=%d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.251     brouard  4818:       for(i=1; i<=nlstate;i++) {
1.265     brouard  4819:        if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," Prev(%d)  N(%d)  N  ",i,i);
1.251     brouard  4820:        fprintf(ficresphtm, "<th>Age</th><th>Prev(%d)</th><th>N(%d)</th><th>N</th>",i,i);
                   4821:       }
1.265     brouard  4822:       if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp, "\n");
1.251     brouard  4823:       fprintf(ficresphtm, "\n");
                   4824:       
                   4825:       /* Header of frequency table by age */
                   4826:       fprintf(ficresphtmfr,"<table style=\"text-align:center; border: 1px solid\">");
                   4827:       fprintf(ficresphtmfr,"<th>Age</th> ");
1.265     brouard  4828:       for(s2=-1; s2 <=nlstate+ndeath; s2++){
1.251     brouard  4829:        for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4830:          if(s2!=0 && m!=0)
                   4831:            fprintf(ficresphtmfr,"<th>%d%d</th> ",s2,m);
1.240     brouard  4832:        }
1.226     brouard  4833:       }
1.251     brouard  4834:       fprintf(ficresphtmfr, "\n");
                   4835:     
                   4836:       /* For each age */
                   4837:       for(iage=iagemin; iage <= iagemax+3; iage++){
                   4838:        fprintf(ficresphtm,"<tr>");
                   4839:        if(iage==iagemax+1){
                   4840:          fprintf(ficlog,"1");
                   4841:          fprintf(ficresphtmfr,"<tr><th>0</th> ");
                   4842:        }else if(iage==iagemax+2){
                   4843:          fprintf(ficlog,"0");
                   4844:          fprintf(ficresphtmfr,"<tr><th>Unknown</th> ");
                   4845:        }else if(iage==iagemax+3){
                   4846:          fprintf(ficlog,"Total");
                   4847:          fprintf(ficresphtmfr,"<tr><th>Total</th> ");
                   4848:        }else{
1.240     brouard  4849:          if(first==1){
1.251     brouard  4850:            first=0;
                   4851:            printf("See log file for details...\n");
                   4852:          }
                   4853:          fprintf(ficresphtmfr,"<tr><th>%d</th> ",iage);
                   4854:          fprintf(ficlog,"Age %d", iage);
                   4855:        }
1.265     brouard  4856:        for(s1=1; s1 <=nlstate ; s1++){
                   4857:          for(m=-1, pp[s1]=0; m <=nlstate+ndeath ; m++)
                   4858:            pp[s1] += freq[s1][m][iage]; 
1.251     brouard  4859:        }
1.265     brouard  4860:        for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4861:          for(m=-1, pos=0; m <=0 ; m++)
1.265     brouard  4862:            pos += freq[s1][m][iage];
                   4863:          if(pp[s1]>=1.e-10){
1.251     brouard  4864:            if(first==1){
1.265     brouard  4865:              printf(" %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4866:            }
1.265     brouard  4867:            fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",s1,pp[s1],s1,100*pos/pp[s1]);
1.251     brouard  4868:          }else{
                   4869:            if(first==1)
1.265     brouard  4870:              printf(" %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
                   4871:            fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",s1,pp[s1],s1);
1.240     brouard  4872:          }
                   4873:        }
                   4874:       
1.265     brouard  4875:        for(s1=1; s1 <=nlstate ; s1++){ 
                   4876:          /* posprop[s1]=0; */
                   4877:          for(m=0, pp[s1]=0; m <=nlstate+ndeath; m++)/* Summing on all ages */
                   4878:            pp[s1] += freq[s1][m][iage];
                   4879:        }       /* pp[s1] is the total number of transitions starting from state s1 and any ending status until this age */
                   4880:       
                   4881:        for(s1=1,pos=0, pospropta=0.; s1 <=nlstate ; s1++){
                   4882:          pos += pp[s1]; /* pos is the total number of transitions until this age */
                   4883:          posprop[s1] += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4884:                                            from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4885:          pospropta += prop[s1][iage]; /* prop is the number of transitions from a live state
                   4886:                                          from s1 at age iage prop[s[m][iind]][(int)agev[m][iind]] += weight[iind] */
                   4887:        }
                   4888:        
                   4889:        /* Writing ficresp */
                   4890:        if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4891:           if( iage <= iagemax){
                   4892:            fprintf(ficresp," %d",iage);
                   4893:           }
                   4894:         }else if( nj==2){
                   4895:           if( iage <= iagemax){
                   4896:            fprintf(ficresp," %d",iage);
                   4897:             for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, " %d %d",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
                   4898:           }
1.240     brouard  4899:        }
1.265     brouard  4900:        for(s1=1; s1 <=nlstate ; s1++){
1.240     brouard  4901:          if(pos>=1.e-5){
1.251     brouard  4902:            if(first==1)
1.265     brouard  4903:              printf(" %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
                   4904:            fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",s1,pp[s1],s1,100*pp[s1]/pos);
1.251     brouard  4905:          }else{
                   4906:            if(first==1)
1.265     brouard  4907:              printf(" %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
                   4908:            fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",s1,pp[s1],s1);
1.251     brouard  4909:          }
                   4910:          if( iage <= iagemax){
                   4911:            if(pos>=1.e-5){
1.265     brouard  4912:              if(cptcoveff==0 && nj==1){ /* no covariate and first pass */
                   4913:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4914:               }else if( nj==2){
                   4915:                fprintf(ficresp," %.5f %.0f %.0f",prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4916:               }
                   4917:              fprintf(ficresphtm,"<th>%d</th><td>%.5f</td><td>%.0f</td><td>%.0f</td>",iage,prop[s1][iage]/pospropta, prop[s1][iage],pospropta);
                   4918:              /*probs[iage][s1][j1]= pp[s1]/pos;*/
                   4919:              /*printf("\niage=%d s1=%d j1=%d %.5f %.0f %.0f %f",iage,s1,j1,pp[s1]/pos, pp[s1],pos,probs[iage][s1][j1]);*/
                   4920:            } else{
                   4921:              if((cptcoveff==0 && nj==1)|| nj==2 ) fprintf(ficresp," NaNq %.0f %.0f",prop[s1][iage],pospropta);
                   4922:              fprintf(ficresphtm,"<th>%d</th><td>NaNq</td><td>%.0f</td><td>%.0f</td>",iage, prop[s1][iage],pospropta);
1.251     brouard  4923:            }
1.240     brouard  4924:          }
1.265     brouard  4925:          pospropt[s1] +=posprop[s1];
                   4926:        } /* end loop s1 */
1.251     brouard  4927:        /* pospropt=0.; */
1.265     brouard  4928:        for(s1=-1; s1 <=nlstate+ndeath; s1++){
1.251     brouard  4929:          for(m=-1; m <=nlstate+ndeath; m++){
1.265     brouard  4930:            if(freq[s1][m][iage] !=0 ) { /* minimizing output */
1.251     brouard  4931:              if(first==1){
1.265     brouard  4932:                printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4933:              }
1.265     brouard  4934:              /* printf(" %d%d=%.0f",s1,m,freq[s1][m][iage]); */
                   4935:              fprintf(ficlog," %d%d=%.0f",s1,m,freq[s1][m][iage]);
1.251     brouard  4936:            }
1.265     brouard  4937:            if(s1!=0 && m!=0)
                   4938:              fprintf(ficresphtmfr,"<td>%.0f</td> ",freq[s1][m][iage]);
1.240     brouard  4939:          }
1.265     brouard  4940:        } /* end loop s1 */
1.251     brouard  4941:        posproptt=0.; 
1.265     brouard  4942:        for(s1=1; s1 <=nlstate; s1++){
                   4943:          posproptt += pospropt[s1];
1.251     brouard  4944:        }
                   4945:        fprintf(ficresphtmfr,"</tr>\n ");
1.265     brouard  4946:        fprintf(ficresphtm,"</tr>\n");
                   4947:        if((cptcoveff==0 && nj==1)|| nj==2 ) {
                   4948:          if(iage <= iagemax)
                   4949:            fprintf(ficresp,"\n");
1.240     brouard  4950:        }
1.251     brouard  4951:        if(first==1)
                   4952:          printf("Others in log...\n");
                   4953:        fprintf(ficlog,"\n");
                   4954:       } /* end loop age iage */
1.265     brouard  4955:       
1.251     brouard  4956:       fprintf(ficresphtm,"<tr><th>Tot</th>");
1.265     brouard  4957:       for(s1=1; s1 <=nlstate ; s1++){
1.251     brouard  4958:        if(posproptt < 1.e-5){
1.265     brouard  4959:          fprintf(ficresphtm,"<td>Nanq</td><td>%.0f</td><td>%.0f</td>",pospropt[s1],posproptt); 
1.251     brouard  4960:        }else{
1.265     brouard  4961:          fprintf(ficresphtm,"<td>%.5f</td><td>%.0f</td><td>%.0f</td>",pospropt[s1]/posproptt,pospropt[s1],posproptt);  
1.240     brouard  4962:        }
1.226     brouard  4963:       }
1.251     brouard  4964:       fprintf(ficresphtm,"</tr>\n");
                   4965:       fprintf(ficresphtm,"</table>\n");
                   4966:       fprintf(ficresphtmfr,"</table>\n");
1.226     brouard  4967:       if(posproptt < 1.e-5){
1.251     brouard  4968:        fprintf(ficresphtm,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
                   4969:        fprintf(ficresphtmfr,"\n <p><b> This combination (%d) is not valid and no result will be produced</b></p>",j1);
1.260     brouard  4970:        fprintf(ficlog,"#  This combination (%d) is not valid and no result will be produced\n",j1);
                   4971:        printf("#  This combination (%d) is not valid and no result will be produced\n",j1);
1.251     brouard  4972:        invalidvarcomb[j1]=1;
1.226     brouard  4973:       }else{
1.251     brouard  4974:        fprintf(ficresphtm,"\n <p> This combination (%d) is valid and result will be produced.</p>",j1);
                   4975:        invalidvarcomb[j1]=0;
1.226     brouard  4976:       }
1.251     brouard  4977:       fprintf(ficresphtmfr,"</table>\n");
                   4978:       fprintf(ficlog,"\n");
                   4979:       if(j!=0){
                   4980:        printf("#Freqsummary: Starting values for combination j1=%d:\n", j1);
1.265     brouard  4981:        for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  4982:          for(k=1; k <=(nlstate+ndeath); k++){
                   4983:            if (k != i) {
1.265     brouard  4984:              for(jj=1; jj <=ncovmodel; jj++){ /* For counting s1 */
1.253     brouard  4985:                if(jj==1){  /* Constant case (in fact cste + age) */
1.251     brouard  4986:                  if(j1==1){ /* All dummy covariates to zero */
                   4987:                    freq[i][k][iagemax+4]=freq[i][k][iagemax+3]; /* Stores case 0 0 0 */
                   4988:                    freq[i][i][iagemax+4]=freq[i][i][iagemax+3]; /* Stores case 0 0 0 */
1.252     brouard  4989:                    printf("%d%d ",i,k);
                   4990:                    fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  4991:                    printf("%12.7f ln(%.0f/%.0f)= %f, OR=%f sd=%f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]),freq[i][k][iagemax+3]/freq[i][i][iagemax+3], sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]));
                   4992:                    fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f \n",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   4993:                    pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
1.251     brouard  4994:                  }
1.253     brouard  4995:                }else if((j1==1) && (jj==2 || nagesqr==1)){ /* age or age*age parameter without covariate V4*age (to be done later) */
                   4996:                  for(iage=iagemin; iage <= iagemax+3; iage++){
                   4997:                    x[iage]= (double)iage;
                   4998:                    y[iage]= log(freq[i][k][iage]/freq[i][i][iage]);
1.265     brouard  4999:                    /* printf("i=%d, k=%d, s1=%d, j1=%d, jj=%d, y[%d]=%f\n",i,k,s1,j1,jj, iage, y[iage]); */
1.253     brouard  5000:                  }
1.268     brouard  5001:                  /* Some are not finite, but linreg will ignore these ages */
                   5002:                  no=0;
1.253     brouard  5003:                  linreg(iagemin,iagemax,&no,x,y,&a,&b,&r, &sa, &sb ); /* y= a+b*x with standard errors */
1.265     brouard  5004:                  pstart[s1]=b;
                   5005:                  pstart[s1-1]=a;
1.252     brouard  5006:                }else if( j1!=1 && (j1==2 || (log(j1-1.)/log(2.)-(int)(log(j1-1.)/log(2.))) <0.010) && ( TvarsDind[(int)(log(j1-1.)/log(2.))+1]+2+nagesqr == jj)  && Dummy[jj-2-nagesqr]==0){ /* We want only if the position, jj, in model corresponds to unique covariate equal to 1 in j1 combination */ 
                   5007:                  printf("j1=%d, jj=%d, (int)(log(j1-1.)/log(2.))+1=%d, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(int)(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
                   5008:                  printf("j1=%d, jj=%d, (log(j1-1.)/log(2.))+1=%f, TvarsDind[(int)(log(j1-1.)/log(2.))+1]=%d\n",j1, jj,(log(j1-1.)/log(2.))+1,TvarsDind[(int)(log(j1-1.)/log(2.))+1]);
1.265     brouard  5009:                  pstart[s1]= log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]));
1.252     brouard  5010:                  printf("%d%d ",i,k);
                   5011:                  fprintf(ficlog,"%d%d ",i,k);
1.265     brouard  5012:                  printf("s1=%d,i=%d,k=%d,p[%d]=%12.7f ln((%.0f/%.0f)/(%.0f/%.0f))= %f, OR=%f sd=%f \n",s1,i,k,s1,p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3],freq[i][k][iagemax+4],freq[i][i][iagemax+4], log((freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4])),(freq[i][k][iagemax+3]/freq[i][i][iagemax+3])/(freq[i][k][iagemax+4]/freq[i][i][iagemax+4]), sqrt(1/freq[i][k][iagemax+3]+1/freq[i][i][iagemax+3]+1/freq[i][k][iagemax+4]+1/freq[i][i][iagemax+4]));
1.251     brouard  5013:                }else{ /* Other cases, like quantitative fixed or varying covariates */
                   5014:                  ;
                   5015:                }
                   5016:                /* printf("%12.7f )", param[i][jj][k]); */
                   5017:                /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5018:                s1++; 
1.251     brouard  5019:              } /* end jj */
                   5020:            } /* end k!= i */
                   5021:          } /* end k */
1.265     brouard  5022:        } /* end i, s1 */
1.251     brouard  5023:       } /* end j !=0 */
                   5024:     } /* end selected combination of covariate j1 */
                   5025:     if(j==0){ /* We can estimate starting values from the occurences in each case */
                   5026:       printf("#Freqsummary: Starting values for the constants:\n");
                   5027:       fprintf(ficlog,"\n");
1.265     brouard  5028:       for(i=1,s1=1; i <=nlstate; i++){
1.251     brouard  5029:        for(k=1; k <=(nlstate+ndeath); k++){
                   5030:          if (k != i) {
                   5031:            printf("%d%d ",i,k);
                   5032:            fprintf(ficlog,"%d%d ",i,k);
                   5033:            for(jj=1; jj <=ncovmodel; jj++){
1.265     brouard  5034:              pstart[s1]=p[s1]; /* Setting pstart to p values by default */
1.253     brouard  5035:              if(jj==1){ /* Age has to be done */
1.265     brouard  5036:                pstart[s1]= log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]);
                   5037:                printf("%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
                   5038:                fprintf(ficlog,"%12.7f ln(%.0f/%.0f)= %12.7f ",p[s1],freq[i][k][iagemax+3],freq[i][i][iagemax+3], log(freq[i][k][iagemax+3]/freq[i][i][iagemax+3]));
1.251     brouard  5039:              }
                   5040:              /* printf("%12.7f )", param[i][jj][k]); */
                   5041:              /* fprintf(ficlog,"%12.7f )", param[i][jj][k]); */
1.265     brouard  5042:              s1++; 
1.250     brouard  5043:            }
1.251     brouard  5044:            printf("\n");
                   5045:            fprintf(ficlog,"\n");
1.250     brouard  5046:          }
                   5047:        }
1.284     brouard  5048:       } /* end of state i */
1.251     brouard  5049:       printf("#Freqsummary\n");
                   5050:       fprintf(ficlog,"\n");
1.265     brouard  5051:       for(s1=-1; s1 <=nlstate+ndeath; s1++){
                   5052:        for(s2=-1; s2 <=nlstate+ndeath; s2++){
                   5053:          /* param[i]|j][k]= freq[s1][s2][iagemax+3] */
                   5054:          printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5055:          fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]);
                   5056:          /* if(freq[s1][s2][iage] !=0 ) { /\* minimizing output *\/ */
                   5057:          /*   printf(" %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
                   5058:          /*   fprintf(ficlog," %d%d=%.0f",s1,s2,freq[s1][s2][iagemax+3]); */
1.251     brouard  5059:          /* } */
                   5060:        }
1.265     brouard  5061:       } /* end loop s1 */
1.251     brouard  5062:       
                   5063:       printf("\n");
                   5064:       fprintf(ficlog,"\n");
                   5065:     } /* end j=0 */
1.249     brouard  5066:   } /* end j */
1.252     brouard  5067: 
1.253     brouard  5068:   if(mle == -2){  /* We want to use these values as starting values */
1.252     brouard  5069:     for(i=1, jk=1; i <=nlstate; i++){
                   5070:       for(j=1; j <=nlstate+ndeath; j++){
                   5071:        if(j!=i){
                   5072:          /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   5073:          printf("%1d%1d",i,j);
                   5074:          fprintf(ficparo,"%1d%1d",i,j);
                   5075:          for(k=1; k<=ncovmodel;k++){
                   5076:            /*    printf(" %lf",param[i][j][k]); */
                   5077:            /*    fprintf(ficparo," %lf",param[i][j][k]); */
                   5078:            p[jk]=pstart[jk];
                   5079:            printf(" %f ",pstart[jk]);
                   5080:            fprintf(ficparo," %f ",pstart[jk]);
                   5081:            jk++;
                   5082:          }
                   5083:          printf("\n");
                   5084:          fprintf(ficparo,"\n");
                   5085:        }
                   5086:       }
                   5087:     }
                   5088:   } /* end mle=-2 */
1.226     brouard  5089:   dateintmean=dateintsum/k2cpt; 
1.296     brouard  5090:   date2dmy(dateintmean,&jintmean,&mintmean,&aintmean);
1.240     brouard  5091:   
1.226     brouard  5092:   fclose(ficresp);
                   5093:   fclose(ficresphtm);
                   5094:   fclose(ficresphtmfr);
1.283     brouard  5095:   free_vector(idq,1,nqfveff);
1.226     brouard  5096:   free_vector(meanq,1,nqfveff);
1.284     brouard  5097:   free_vector(stdq,1,nqfveff);
1.226     brouard  5098:   free_matrix(meanqt,1,lastpass,1,nqtveff);
1.253     brouard  5099:   free_vector(x, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
                   5100:   free_vector(y, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.251     brouard  5101:   free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5102:   free_vector(pospropt,1,nlstate);
                   5103:   free_vector(posprop,1,nlstate);
1.251     brouard  5104:   free_matrix(prop,1,nlstate,iagemin-AGEMARGE, iagemax+4+AGEMARGE);
1.226     brouard  5105:   free_vector(pp,1,nlstate);
                   5106:   /* End of freqsummary */
                   5107: }
1.126     brouard  5108: 
1.268     brouard  5109: /* Simple linear regression */
                   5110: int linreg(int ifi, int ila, int *no, const double x[], const double y[], double* a, double* b, double* r, double* sa, double * sb) {
                   5111: 
                   5112:   /* y=a+bx regression */
                   5113:   double   sumx = 0.0;                        /* sum of x                      */
                   5114:   double   sumx2 = 0.0;                       /* sum of x**2                   */
                   5115:   double   sumxy = 0.0;                       /* sum of x * y                  */
                   5116:   double   sumy = 0.0;                        /* sum of y                      */
                   5117:   double   sumy2 = 0.0;                       /* sum of y**2                   */
                   5118:   double   sume2 = 0.0;                       /* sum of square or residuals */
                   5119:   double yhat;
                   5120:   
                   5121:   double denom=0;
                   5122:   int i;
                   5123:   int ne=*no;
                   5124:   
                   5125:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5126:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5127:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5128:       continue;
                   5129:     }
                   5130:     ne=ne+1;
                   5131:     sumx  += x[i];       
                   5132:     sumx2 += x[i]*x[i];  
                   5133:     sumxy += x[i] * y[i];
                   5134:     sumy  += y[i];      
                   5135:     sumy2 += y[i]*y[i]; 
                   5136:     denom = (ne * sumx2 - sumx*sumx);
                   5137:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5138:   } 
                   5139:   
                   5140:   denom = (ne * sumx2 - sumx*sumx);
                   5141:   if (denom == 0) {
                   5142:     // vertical, slope m is infinity
                   5143:     *b = INFINITY;
                   5144:     *a = 0;
                   5145:     if (r) *r = 0;
                   5146:     return 1;
                   5147:   }
                   5148:   
                   5149:   *b = (ne * sumxy  -  sumx * sumy) / denom;
                   5150:   *a = (sumy * sumx2  -  sumx * sumxy) / denom;
                   5151:   if (r!=NULL) {
                   5152:     *r = (sumxy - sumx * sumy / ne) /          /* compute correlation coeff     */
                   5153:       sqrt((sumx2 - sumx*sumx/ne) *
                   5154:           (sumy2 - sumy*sumy/ne));
                   5155:   }
                   5156:   *no=ne;
                   5157:   for ( i=ifi, ne=0;i<=ila;i++) {
                   5158:     if(!isfinite(x[i]) || !isfinite(y[i])){
                   5159:       /* printf(" x[%d]=%f, y[%d]=%f\n",i,x[i],i,y[i]); */
                   5160:       continue;
                   5161:     }
                   5162:     ne=ne+1;
                   5163:     yhat = y[i] - *a -*b* x[i];
                   5164:     sume2  += yhat * yhat ;       
                   5165:     
                   5166:     denom = (ne * sumx2 - sumx*sumx);
                   5167:     /* printf("ne=%d, i=%d,x[%d]=%f, y[%d]=%f sumx=%f, sumx2=%f, sumxy=%f, sumy=%f, sumy2=%f, denom=%f\n",ne,i,i,x[i],i,y[i], sumx, sumx2,sumxy, sumy, sumy2,denom); */
                   5168:   } 
                   5169:   *sb = sqrt(sume2/(double)(ne-2)/(sumx2 - sumx * sumx /(double)ne));
                   5170:   *sa= *sb * sqrt(sumx2/ne);
                   5171:   
                   5172:   return 0; 
                   5173: }
                   5174: 
1.126     brouard  5175: /************ Prevalence ********************/
1.227     brouard  5176: void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
                   5177: {  
                   5178:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   5179:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   5180:      We still use firstpass and lastpass as another selection.
                   5181:   */
1.126     brouard  5182:  
1.227     brouard  5183:   int i, m, jk, j1, bool, z1,j, iv;
                   5184:   int mi; /* Effective wave */
                   5185:   int iage;
                   5186:   double agebegin, ageend;
                   5187: 
                   5188:   double **prop;
                   5189:   double posprop; 
                   5190:   double  y2; /* in fractional years */
                   5191:   int iagemin, iagemax;
                   5192:   int first; /** to stop verbosity which is redirected to log file */
                   5193: 
                   5194:   iagemin= (int) agemin;
                   5195:   iagemax= (int) agemax;
                   5196:   /*pp=vector(1,nlstate);*/
1.251     brouard  5197:   prop=matrix(1,nlstate,iagemin-AGEMARGE,iagemax+4+AGEMARGE); 
1.227     brouard  5198:   /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
                   5199:   j1=0;
1.222     brouard  5200:   
1.227     brouard  5201:   /*j=cptcoveff;*/
                   5202:   if (cptcovn<1) {j=1;ncodemax[1]=1;}
1.222     brouard  5203:   
1.288     brouard  5204:   first=0;
1.227     brouard  5205:   for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){ /* For each combination of covariate */
                   5206:     for (i=1; i<=nlstate; i++)  
1.251     brouard  5207:       for(iage=iagemin-AGEMARGE; iage <= iagemax+4+AGEMARGE; iage++)
1.227     brouard  5208:        prop[i][iage]=0.0;
                   5209:     printf("Prevalence combination of varying and fixed dummies %d\n",j1);
                   5210:     /* fprintf(ficlog," V%d=%d ",Tvaraff[j1],nbcode[Tvaraff[j1]][codtabm(k,j1)]); */
                   5211:     fprintf(ficlog,"Prevalence combination of varying and fixed dummies %d\n",j1);
                   5212:     
                   5213:     for (i=1; i<=imx; i++) { /* Each individual */
                   5214:       bool=1;
                   5215:       /* for(m=firstpass; m<=lastpass; m++){/\* Other selection (we can limit to certain interviews*\/ */
                   5216:       for(mi=1; mi<wav[i];mi++){ /* For this wave too look where individual can be counted V4=0 V3=0 */
                   5217:        m=mw[mi][i];
                   5218:        /* Tmodelind[z1]=k is the position of the varying covariate in the model, but which # within 1 to ntv? */
                   5219:        /* Tvar[Tmodelind[z1]] is the n of Vn; n-ncovcol-nqv is the first time varying covariate or iv */
                   5220:        for (z1=1; z1<=cptcoveff; z1++){
                   5221:          if( Fixed[Tmodelind[z1]]==1){
                   5222:            iv= Tvar[Tmodelind[z1]]-ncovcol-nqv;
                   5223:            if (cotvar[m][iv][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) /* iv=1 to ntv, right modality */
                   5224:              bool=0;
                   5225:          }else if( Fixed[Tmodelind[z1]]== 0)  /* fixed */
                   5226:            if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) {
                   5227:              bool=0;
                   5228:            }
                   5229:        }
                   5230:        if(bool==1){ /* Otherwise we skip that wave/person */
                   5231:          agebegin=agev[m][i]; /* Age at beginning of wave before transition*/
                   5232:          /* ageend=agev[m][i]+(dh[m][i])*stepm/YEARM; /\* Age at end of wave and transition *\/ */
                   5233:          if(m >=firstpass && m <=lastpass){
                   5234:            y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
                   5235:            if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
                   5236:              if(agev[m][i]==0) agev[m][i]=iagemax+1;
                   5237:              if(agev[m][i]==1) agev[m][i]=iagemax+2;
1.251     brouard  5238:              if((int)agev[m][i] <iagemin-AGEMARGE || (int)agev[m][i] >iagemax+4+AGEMARGE){
1.227     brouard  5239:                printf("Error on individual # %d agev[m][i]=%f <%d-%d or > %d+3+%d  m=%d; either change agemin or agemax or fix data\n",i, agev[m][i],iagemin,AGEMARGE, iagemax,AGEMARGE,m); 
                   5240:                exit(1);
                   5241:              }
                   5242:              if (s[m][i]>0 && s[m][i]<=nlstate) { 
                   5243:                /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
                   5244:                prop[s[m][i]][(int)agev[m][i]] += weight[i];/* At age of beginning of transition, where status is known */
                   5245:                prop[s[m][i]][iagemax+3] += weight[i]; 
                   5246:              } /* end valid statuses */ 
                   5247:            } /* end selection of dates */
                   5248:          } /* end selection of waves */
                   5249:        } /* end bool */
                   5250:       } /* end wave */
                   5251:     } /* end individual */
                   5252:     for(i=iagemin; i <= iagemax+3; i++){  
                   5253:       for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
                   5254:        posprop += prop[jk][i]; 
                   5255:       } 
                   5256:       
                   5257:       for(jk=1; jk <=nlstate ; jk++){      
                   5258:        if( i <=  iagemax){ 
                   5259:          if(posprop>=1.e-5){ 
                   5260:            probs[i][jk][j1]= prop[jk][i]/posprop;
                   5261:          } else{
1.288     brouard  5262:            if(!first){
                   5263:              first=1;
1.266     brouard  5264:              printf("Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases\nSee others in log file...\n",jk,i,jk, j1,probs[i][jk][j1]);
                   5265:            }else{
1.288     brouard  5266:              fprintf(ficlog,"Warning Observed prevalence doesn't sum to 1 for state %d: probs[%d][%d][%d]=%lf because of lack of cases.\n",jk,i,jk, j1,probs[i][jk][j1]);
1.227     brouard  5267:            }
                   5268:          }
                   5269:        } 
                   5270:       }/* end jk */ 
                   5271:     }/* end i */ 
1.222     brouard  5272:      /*} *//* end i1 */
1.227     brouard  5273:   } /* end j1 */
1.222     brouard  5274:   
1.227     brouard  5275:   /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
                   5276:   /*free_vector(pp,1,nlstate);*/
1.251     brouard  5277:   free_matrix(prop,1,nlstate, iagemin-AGEMARGE,iagemax+4+AGEMARGE);
1.227     brouard  5278: }  /* End of prevalence */
1.126     brouard  5279: 
                   5280: /************* Waves Concatenation ***************/
                   5281: 
                   5282: void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
                   5283: {
1.298     brouard  5284:   /* Concatenates waves: wav[i] is the number of effective (useful waves in the sense that a non interview is useless) of individual i.
1.126     brouard  5285:      Death is a valid wave (if date is known).
                   5286:      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
                   5287:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
1.298     brouard  5288:      and mw[mi+1][i]. dh depends on stepm. s[m][i] exists for any wave from firstpass to lastpass
1.227     brouard  5289:   */
1.126     brouard  5290: 
1.224     brouard  5291:   int i=0, mi=0, m=0, mli=0;
1.126     brouard  5292:   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
                   5293:      double sum=0., jmean=0.;*/
1.224     brouard  5294:   int first=0, firstwo=0, firsthree=0, firstfour=0, firstfiv=0;
1.126     brouard  5295:   int j, k=0,jk, ju, jl;
                   5296:   double sum=0.;
                   5297:   first=0;
1.214     brouard  5298:   firstwo=0;
1.217     brouard  5299:   firsthree=0;
1.218     brouard  5300:   firstfour=0;
1.164     brouard  5301:   jmin=100000;
1.126     brouard  5302:   jmax=-1;
                   5303:   jmean=0.;
1.224     brouard  5304: 
                   5305: /* Treating live states */
1.214     brouard  5306:   for(i=1; i<=imx; i++){  /* For simple cases and if state is death */
1.224     brouard  5307:     mi=0;  /* First valid wave */
1.227     brouard  5308:     mli=0; /* Last valid wave */
1.309     brouard  5309:     m=firstpass;  /* Loop on waves */
                   5310:     while(s[m][i] <= nlstate){  /* a live state or unknown state  */
1.227     brouard  5311:       if(m >firstpass && s[m][i]==s[m-1][i] && mint[m][i]==mint[m-1][i] && anint[m][i]==anint[m-1][i]){/* Two succesive identical information on wave m */
                   5312:        mli=m-1;/* mw[++mi][i]=m-1; */
                   5313:       }else if(s[m][i]>=1 || s[m][i]==-4 || s[m][i]==-5){ /* Since 0.98r4 if status=-2 vital status is really unknown, wave should be skipped */
1.309     brouard  5314:        mw[++mi][i]=m; /* Valid wave: incrementing mi and updating mi; mw[mi] is the wave number of mi_th valid transition   */
1.227     brouard  5315:        mli=m;
1.224     brouard  5316:       } /* else might be a useless wave  -1 and mi is not incremented and mw[mi] not updated */
                   5317:       if(m < lastpass){ /* m < lastpass, standard case */
1.227     brouard  5318:        m++; /* mi gives the "effective" current wave, m the current wave, go to next wave by incrementing m */
1.216     brouard  5319:       }
1.309     brouard  5320:       else{ /* m = lastpass, eventual special issue with warning */
1.224     brouard  5321: #ifdef UNKNOWNSTATUSNOTCONTRIBUTING
1.227     brouard  5322:        break;
1.224     brouard  5323: #else
1.309     brouard  5324:        if(s[m][i]==-1 && (int) andc[i] == 9999 && (int)anint[m][i] != 9999){ /* case -2 (vital status unknown is warned later */
1.227     brouard  5325:          if(firsthree == 0){
1.302     brouard  5326:            printf("Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.227     brouard  5327:            firsthree=1;
                   5328:          }
1.302     brouard  5329:          fprintf(ficlog,"Information! Unknown status for individual %ld line=%d occurred at last wave %d at known date %d/%d. Please, check if your unknown date of death %d/%d means a live state %d at wave %d. This case(%d)/wave(%d) contributes to the likelihood as 1-p_{%d%d} .\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], (int) moisdc[i], (int) andc[i], s[m][i], m, i, m, s[m][i], nlstate+ndeath);
1.309     brouard  5330:          mw[++mi][i]=m; /* Valid transition with unknown status */
1.227     brouard  5331:          mli=m;
                   5332:        }
                   5333:        if(s[m][i]==-2){ /* Vital status is really unknown */
                   5334:          nbwarn++;
1.309     brouard  5335:          if((int)anint[m][i] == 9999){  /*  Has the vital status really been verified?not a transition */
1.227     brouard  5336:            printf("Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5337:            fprintf(ficlog,"Warning! Vital status for individual %ld (line=%d) at last wave %d interviewed at date %d/%d is unknown %d. Please, check if the vital status and the date of death %d/%d are really unknown. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], (int) moisdc[i], (int) andc[i], i, m);
                   5338:          }
                   5339:          break;
                   5340:        }
                   5341:        break;
1.224     brouard  5342: #endif
1.227     brouard  5343:       }/* End m >= lastpass */
1.126     brouard  5344:     }/* end while */
1.224     brouard  5345: 
1.227     brouard  5346:     /* mi is the last effective wave, m is lastpass, mw[j][i] gives the # of j-th effective wave for individual i */
1.216     brouard  5347:     /* After last pass */
1.224     brouard  5348: /* Treating death states */
1.214     brouard  5349:     if (s[m][i] > nlstate){  /* In a death state */
1.227     brouard  5350:       /* if( mint[m][i]==mdc[m][i] && anint[m][i]==andc[m][i]){ /\* same date of death and date of interview *\/ */
                   5351:       /* } */
1.126     brouard  5352:       mi++;    /* Death is another wave */
                   5353:       /* if(mi==0)  never been interviewed correctly before death */
1.227     brouard  5354:       /* Only death is a correct wave */
1.126     brouard  5355:       mw[mi][i]=m;
1.257     brouard  5356:     } /* else not in a death state */
1.224     brouard  5357: #ifndef DISPATCHINGKNOWNDEATHAFTERLASTWAVE
1.257     brouard  5358:     else if ((int) andc[i] != 9999) {  /* Date of death is known */
1.218     brouard  5359:       if ((int)anint[m][i]!= 9999) { /* date of last interview is known */
1.309     brouard  5360:        if((andc[i]+moisdc[i]/12.) <=(anint[m][i]+mint[m][i]/12.)){ /* month of death occured before last wave month and status should have been death instead of -1 */
1.227     brouard  5361:          nbwarn++;
                   5362:          if(firstfiv==0){
1.309     brouard  5363:            printf("Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5364:            firstfiv=1;
                   5365:          }else{
1.309     brouard  5366:            fprintf(ficlog,"Warning! Death for individual %ld line=%d occurred at %d/%d before last wave %d, interviewed on %d/%d and should have been coded as death instead of '%d'. This case (%d)/wave (%d) is contributing to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5367:          }
1.309     brouard  5368:            s[m][i]=nlstate+1; /* Fixing the status as death. Be careful if multiple death states */
                   5369:        }else{ /* Month of Death occured afer last wave month, potential bias */
1.227     brouard  5370:          nberr++;
                   5371:          if(firstwo==0){
1.309     brouard  5372:            printf("Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5373:            firstwo=1;
                   5374:          }
1.309     brouard  5375:          fprintf(ficlog,"Error! Death for individual %ld line=%d occurred at %d/%d after last wave %d interviewed at %d/%d with status %d. Potential bias if other individuals are still alive on this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood. Please add a new fictitious wave at the date of last vital status scan, with a dead status. See documentation\n\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5376:        }
1.257     brouard  5377:       }else{ /* if date of interview is unknown */
1.227     brouard  5378:        /* death is known but not confirmed by death status at any wave */
                   5379:        if(firstfour==0){
1.309     brouard  5380:          printf("Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\nOthers in log file only\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.227     brouard  5381:          firstfour=1;
                   5382:        }
1.309     brouard  5383:        fprintf(ficlog,"Error! Death for individual %ld line=%d  occurred %d/%d but not confirmed by any death status for any wave, including last wave %d at unknown date %d/%d  with status %d. Potential bias if other individuals are still alive at this date but ignored. This case (%d)/wave (%d) is skipped, no contribution to likelihood.\n",num[i],i,(int) moisdc[i], (int) andc[i], lastpass,(int)mint[m][i],(int)anint[m][i], s[m][i], i,m );
1.214     brouard  5384:       }
1.224     brouard  5385:     } /* end if date of death is known */
                   5386: #endif
1.309     brouard  5387:     wav[i]=mi; /* mi should be the last effective wave (or mli),  */
                   5388:     /* wav[i]=mw[mi][i];   */
1.126     brouard  5389:     if(mi==0){
                   5390:       nbwarn++;
                   5391:       if(first==0){
1.227     brouard  5392:        printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
                   5393:        first=1;
1.126     brouard  5394:       }
                   5395:       if(first==1){
1.227     brouard  5396:        fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
1.126     brouard  5397:       }
                   5398:     } /* end mi==0 */
                   5399:   } /* End individuals */
1.214     brouard  5400:   /* wav and mw are no more changed */
1.223     brouard  5401:        
1.214     brouard  5402:   
1.126     brouard  5403:   for(i=1; i<=imx; i++){
                   5404:     for(mi=1; mi<wav[i];mi++){
                   5405:       if (stepm <=0)
1.227     brouard  5406:        dh[mi][i]=1;
1.126     brouard  5407:       else{
1.260     brouard  5408:        if (s[mw[mi+1][i]][i] > nlstate) { /* A death, but what if date is unknown? */
1.227     brouard  5409:          if (agedc[i] < 2*AGESUP) {
                   5410:            j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                   5411:            if(j==0) j=1;  /* Survives at least one month after exam */
                   5412:            else if(j<0){
                   5413:              nberr++;
                   5414:              printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5415:              j=1; /* Temporary Dangerous patch */
                   5416:              printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5417:              fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5418:              fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
                   5419:            }
                   5420:            k=k+1;
                   5421:            if (j >= jmax){
                   5422:              jmax=j;
                   5423:              ijmax=i;
                   5424:            }
                   5425:            if (j <= jmin){
                   5426:              jmin=j;
                   5427:              ijmin=i;
                   5428:            }
                   5429:            sum=sum+j;
                   5430:            /*if (j<0) printf("j=%d num=%d \n",j,i);*/
                   5431:            /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
                   5432:          }
                   5433:        }
                   5434:        else{
                   5435:          j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
1.126     brouard  5436: /*       if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
1.223     brouard  5437:                                        
1.227     brouard  5438:          k=k+1;
                   5439:          if (j >= jmax) {
                   5440:            jmax=j;
                   5441:            ijmax=i;
                   5442:          }
                   5443:          else if (j <= jmin){
                   5444:            jmin=j;
                   5445:            ijmin=i;
                   5446:          }
                   5447:          /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                   5448:          /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
                   5449:          if(j<0){
                   5450:            nberr++;
                   5451:            printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5452:            fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                   5453:          }
                   5454:          sum=sum+j;
                   5455:        }
                   5456:        jk= j/stepm;
                   5457:        jl= j -jk*stepm;
                   5458:        ju= j -(jk+1)*stepm;
                   5459:        if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
                   5460:          if(jl==0){
                   5461:            dh[mi][i]=jk;
                   5462:            bh[mi][i]=0;
                   5463:          }else{ /* We want a negative bias in order to only have interpolation ie
                   5464:                  * to avoid the price of an extra matrix product in likelihood */
                   5465:            dh[mi][i]=jk+1;
                   5466:            bh[mi][i]=ju;
                   5467:          }
                   5468:        }else{
                   5469:          if(jl <= -ju){
                   5470:            dh[mi][i]=jk;
                   5471:            bh[mi][i]=jl;       /* bias is positive if real duration
                   5472:                                 * is higher than the multiple of stepm and negative otherwise.
                   5473:                                 */
                   5474:          }
                   5475:          else{
                   5476:            dh[mi][i]=jk+1;
                   5477:            bh[mi][i]=ju;
                   5478:          }
                   5479:          if(dh[mi][i]==0){
                   5480:            dh[mi][i]=1; /* At least one step */
                   5481:            bh[mi][i]=ju; /* At least one step */
                   5482:            /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
                   5483:          }
                   5484:        } /* end if mle */
1.126     brouard  5485:       }
                   5486:     } /* end wave */
                   5487:   }
                   5488:   jmean=sum/k;
                   5489:   printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
1.141     brouard  5490:   fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
1.227     brouard  5491: }
1.126     brouard  5492: 
                   5493: /*********** Tricode ****************************/
1.220     brouard  5494:  void tricode(int *cptcov, int *Tvar, int **nbcode, int imx, int *Ndum)
1.242     brouard  5495:  {
                   5496:    /**< Uses cptcovn+2*cptcovprod as the number of covariates */
                   5497:    /*    Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
                   5498:     * Boring subroutine which should only output nbcode[Tvar[j]][k]
                   5499:     * Tvar[5] in V2+V1+V3*age+V2*V4 is 4 (V4) even it is a time varying or quantitative variable
                   5500:     * nbcode[Tvar[5]][1]= nbcode[4][1]=0, nbcode[4][2]=1 (usually);
                   5501:     */
1.130     brouard  5502: 
1.242     brouard  5503:    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
                   5504:    int modmaxcovj=0; /* Modality max of covariates j */
                   5505:    int cptcode=0; /* Modality max of covariates j */
                   5506:    int modmincovj=0; /* Modality min of covariates j */
1.145     brouard  5507: 
                   5508: 
1.242     brouard  5509:    /* cptcoveff=0;  */
                   5510:    /* *cptcov=0; */
1.126     brouard  5511:  
1.242     brouard  5512:    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
1.285     brouard  5513:    for (k=1; k <= maxncov; k++)
                   5514:      for(j=1; j<=2; j++)
                   5515:        nbcode[k][j]=0; /* Valgrind */
1.126     brouard  5516: 
1.242     brouard  5517:    /* Loop on covariates without age and products and no quantitative variable */
                   5518:    for (k=1; k<=cptcovt; k++) { /* From model V1 + V2*age + V3 + V3*V4 keeps V1 + V3 = 2 only */
                   5519:      for (j=-1; (j < maxncov); j++) Ndum[j]=0;
                   5520:      if(Dummy[k]==0 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5521:        switch(Fixed[k]) {
                   5522:        case 0: /* Testing on fixed dummy covariate, simple or product of fixed */
1.311     brouard  5523:         modmaxcovj=0;
                   5524:         modmincovj=0;
1.242     brouard  5525:         for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5526:           ij=(int)(covar[Tvar[k]][i]);
                   5527:           /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
                   5528:            * If product of Vn*Vm, still boolean *:
                   5529:            * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
                   5530:            * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
                   5531:           /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
                   5532:              modality of the nth covariate of individual i. */
                   5533:           if (ij > modmaxcovj)
                   5534:             modmaxcovj=ij; 
                   5535:           else if (ij < modmincovj) 
                   5536:             modmincovj=ij; 
1.287     brouard  5537:           if (ij <0 || ij >1 ){
1.311     brouard  5538:             printf("ERROR, IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5539:             fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=-1, individual %d will be skipped.\n",Tvar[k],i);
                   5540:             fflush(ficlog);
                   5541:             exit(1);
1.287     brouard  5542:           }
                   5543:           if ((ij < -1) || (ij > NCOVMAX)){
1.242     brouard  5544:             printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
                   5545:             exit(1);
                   5546:           }else
                   5547:             Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
                   5548:           /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
                   5549:           /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
                   5550:           /* getting the maximum value of the modality of the covariate
                   5551:              (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
                   5552:              female ies 1, then modmaxcovj=1.
                   5553:           */
                   5554:         } /* end for loop on individuals i */
                   5555:         printf(" Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5556:         fprintf(ficlog," Minimal and maximal values of %d th (fixed) covariate V%d: min=%d max=%d \n", k, Tvar[k], modmincovj, modmaxcovj);
                   5557:         cptcode=modmaxcovj;
                   5558:         /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
                   5559:         /*for (i=0; i<=cptcode; i++) {*/
                   5560:         for (j=modmincovj;  j<=modmaxcovj; j++) { /* j=-1 ? 0 and 1*//* For each value j of the modality of model-cov k */
                   5561:           printf("Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5562:           fprintf(ficlog, "Frequencies of (fixed) covariate %d ie V%d with value %d: %d\n", k, Tvar[k], j, Ndum[j]);
                   5563:           if( Ndum[j] != 0 ){ /* Counts if nobody answered modality j ie empty modality, we skip it and reorder */
                   5564:             if( j != -1){
                   5565:               ncodemax[k]++;  /* ncodemax[k]= Number of modalities of the k th
                   5566:                                  covariate for which somebody answered excluding 
                   5567:                                  undefined. Usually 2: 0 and 1. */
                   5568:             }
                   5569:             ncodemaxwundef[k]++; /* ncodemax[j]= Number of modalities of the k th
                   5570:                                     covariate for which somebody answered including 
                   5571:                                     undefined. Usually 3: -1, 0 and 1. */
                   5572:           }    /* In fact  ncodemax[k]=2 (dichotom. variables only) but it could be more for
                   5573:                 * historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
                   5574:         } /* Ndum[-1] number of undefined modalities */
1.231     brouard  5575:                        
1.242     brouard  5576:         /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
                   5577:         /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. */
                   5578:         /* If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125; */
                   5579:         /* modmincovj=3; modmaxcovj = 7; */
                   5580:         /* There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3; */
                   5581:         /* which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10; */
                   5582:         /*              defining two dummy variables: variables V1_1 and V1_2.*/
                   5583:         /* nbcode[Tvar[j]][ij]=k; */
                   5584:         /* nbcode[Tvar[j]][1]=0; */
                   5585:         /* nbcode[Tvar[j]][2]=1; */
                   5586:         /* nbcode[Tvar[j]][3]=2; */
                   5587:         /* To be continued (not working yet). */
                   5588:         ij=0; /* ij is similar to i but can jump over null modalities */
1.287     brouard  5589: 
                   5590:         /* for (i=modmincovj; i<=modmaxcovj; i++) { */ /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
                   5591:         /* Skipping the case of missing values by reducing nbcode to 0 and 1 and not -1, 0, 1 */
                   5592:         /* model=V1+V2+V3, if V2=-1, 0 or 1, then nbcode[2][1]=0 and nbcode[2][2]=1 instead of
                   5593:          * nbcode[2][1]=-1, nbcode[2][2]=0 and nbcode[2][3]=1 */
                   5594:         /*, could be restored in the future */
                   5595:         for (i=0; i<=1; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
1.242     brouard  5596:           if (Ndum[i] == 0) { /* If nobody responded to this modality k */
                   5597:             break;
                   5598:           }
                   5599:           ij++;
1.287     brouard  5600:           nbcode[Tvar[k]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality. nbcode[1][1]=0 nbcode[1][2]=1 . Could be -1*/
1.242     brouard  5601:           cptcode = ij; /* New max modality for covar j */
                   5602:         } /* end of loop on modality i=-1 to 1 or more */
                   5603:         break;
                   5604:        case 1: /* Testing on varying covariate, could be simple and
                   5605:                * should look at waves or product of fixed *
                   5606:                * varying. No time to test -1, assuming 0 and 1 only */
                   5607:         ij=0;
                   5608:         for(i=0; i<=1;i++){
                   5609:           nbcode[Tvar[k]][++ij]=i;
                   5610:         }
                   5611:         break;
                   5612:        default:
                   5613:         break;
                   5614:        } /* end switch */
                   5615:      } /* end dummy test */
1.311     brouard  5616:      if(Dummy[k]==1 && Typevar[k] !=1){ /* Dummy covariate and not age product */ 
                   5617:        for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the  modality of this covariate Vj*/
                   5618:         if(isnan(covar[Tvar[k]][i])){
                   5619:           printf("ERROR, IMaCh doesn't treat fixed quantitative covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5620:           fprintf(ficlog,"ERROR, currently IMaCh doesn't treat covariate with missing values V%d=., individual %d will be skipped.\n",Tvar[k],i);
                   5621:           fflush(ficlog);
                   5622:           exit(1);
                   5623:          }
                   5624:        }
                   5625:      }
1.287     brouard  5626:    } /* end of loop on model-covariate k. nbcode[Tvark][1]=-1, nbcode[Tvark][1]=0 and nbcode[Tvark][2]=1 sets the value of covariate k*/  
1.242     brouard  5627:   
                   5628:    for (k=-1; k< maxncov; k++) Ndum[k]=0; 
                   5629:    /* Look at fixed dummy (single or product) covariates to check empty modalities */
                   5630:    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
                   5631:      /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
                   5632:      ij=Tvar[i]; /* Tvar 5,4,3,6,5,7,1,4 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V4*age */ 
                   5633:      Ndum[ij]++; /* Count the # of 1, 2 etc: {1,1,1,2,2,1,1} because V1 once, V2 once, two V4 and V5 in above */
                   5634:      /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1,  {2, 1, 1, 1, 2, 1, 1, 0, 0} */
                   5635:    } /* V4+V3+V5, Ndum[1]@5={0, 0, 1, 1, 1} */
                   5636:   
                   5637:    ij=0;
                   5638:    /* for (i=0; i<=  maxncov-1; i++) { /\* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) *\/ */
                   5639:    for (k=1; k<=  cptcovt; k++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
                   5640:      /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5641:      /* if((Ndum[i]!=0) && (i<=ncovcol)){  /\* Tvar[i] <= ncovmodel ? *\/ */
                   5642:      if(Ndum[Tvar[k]]!=0 && Dummy[k] == 0 && Typevar[k]==0){  /* Only Dummy and non empty in the model */
                   5643:        /* If product not in single variable we don't print results */
                   5644:        /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
                   5645:        ++ij;/* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, */
                   5646:        Tvaraff[ij]=Tvar[k]; /* For printing combination *//* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, Tvar {5, 4, 3, 6, 5, 2, 7, 1, 1} Tvaraff={4, 3, 1} V4, V3, V1*/
                   5647:        Tmodelind[ij]=k; /* Tmodelind: index in model of dummies Tmodelind[1]=2 V4: pos=2; V3: pos=3, V1=9 {2, 3, 9, ?, ?,} */
                   5648:        TmodelInvind[ij]=Tvar[k]- ncovcol-nqv; /* Inverse TmodelInvind[2=V4]=2 second dummy varying cov (V4)4-1-1 {0, 2, 1, } TmodelInvind[3]=1 */
                   5649:        if(Fixed[k]!=0)
                   5650:         anyvaryingduminmodel=1;
                   5651:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv)){ */
                   5652:        /*   Tvaraff[++ij]=-10; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5653:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv)){ */
                   5654:        /*   Tvaraff[++ij]=i; /\*For printing (unclear) *\/ */
                   5655:        /* }else if((Ndum[i]!=0) && (i<=ncovcol+nqv+ntv+nqtv)){ */
                   5656:        /*   Tvaraff[++ij]=-20; /\* Dont'n know how to treat quantitative variables yet *\/ */
                   5657:      } 
                   5658:    } /* Tvaraff[1]@5 {3, 4, -20, 0, 0} Very strange */
                   5659:    /* ij--; */
                   5660:    /* cptcoveff=ij; /\*Number of total covariates*\/ */
                   5661:    *cptcov=ij; /*Number of total real effective covariates: effective
                   5662:                * because they can be excluded from the model and real
                   5663:                * if in the model but excluded because missing values, but how to get k from ij?*/
                   5664:    for(j=ij+1; j<= cptcovt; j++){
                   5665:      Tvaraff[j]=0;
                   5666:      Tmodelind[j]=0;
                   5667:    }
                   5668:    for(j=ntveff+1; j<= cptcovt; j++){
                   5669:      TmodelInvind[j]=0;
                   5670:    }
                   5671:    /* To be sorted */
                   5672:    ;
                   5673:  }
1.126     brouard  5674: 
1.145     brouard  5675: 
1.126     brouard  5676: /*********** Health Expectancies ****************/
                   5677: 
1.235     brouard  5678:  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[], int nres )
1.126     brouard  5679: 
                   5680: {
                   5681:   /* Health expectancies, no variances */
1.164     brouard  5682:   int i, j, nhstepm, hstepm, h, nstepm;
1.126     brouard  5683:   int nhstepma, nstepma; /* Decreasing with age */
                   5684:   double age, agelim, hf;
                   5685:   double ***p3mat;
                   5686:   double eip;
                   5687: 
1.238     brouard  5688:   /* pstamp(ficreseij); */
1.126     brouard  5689:   fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
                   5690:   fprintf(ficreseij,"# Age");
                   5691:   for(i=1; i<=nlstate;i++){
                   5692:     for(j=1; j<=nlstate;j++){
                   5693:       fprintf(ficreseij," e%1d%1d ",i,j);
                   5694:     }
                   5695:     fprintf(ficreseij," e%1d. ",i);
                   5696:   }
                   5697:   fprintf(ficreseij,"\n");
                   5698: 
                   5699:   
                   5700:   if(estepm < stepm){
                   5701:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5702:   }
                   5703:   else  hstepm=estepm;   
                   5704:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5705:    * This is mainly to measure the difference between two models: for example
                   5706:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5707:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5708:    * progression in between and thus overestimating or underestimating according
                   5709:    * to the curvature of the survival function. If, for the same date, we 
                   5710:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5711:    * to compare the new estimate of Life expectancy with the same linear 
                   5712:    * hypothesis. A more precise result, taking into account a more precise
                   5713:    * curvature will be obtained if estepm is as small as stepm. */
                   5714: 
                   5715:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5716:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5717:      nhstepm is the number of hstepm from age to agelim 
                   5718:      nstepm is the number of stepm from age to agelin. 
1.270     brouard  5719:      Look at hpijx to understand the reason which relies in memory size consideration
1.126     brouard  5720:      and note for a fixed period like estepm months */
                   5721:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5722:      survival function given by stepm (the optimization length). Unfortunately it
                   5723:      means that if the survival funtion is printed only each two years of age and if
                   5724:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5725:      results. So we changed our mind and took the option of the best precision.
                   5726:   */
                   5727:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5728: 
                   5729:   agelim=AGESUP;
                   5730:   /* If stepm=6 months */
                   5731:     /* Computed by stepm unit matrices, product of hstepm matrices, stored
                   5732:        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
                   5733:     
                   5734: /* nhstepm age range expressed in number of stepm */
                   5735:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5736:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5737:   /* if (stepm >= YEARM) hstepm=1;*/
                   5738:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5739:   p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5740: 
                   5741:   for (age=bage; age<=fage; age ++){ 
                   5742:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5743:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5744:     /* if (stepm >= YEARM) hstepm=1;*/
                   5745:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
                   5746: 
                   5747:     /* If stepm=6 months */
                   5748:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5749:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5750:     
1.235     brouard  5751:     hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij, nres);  
1.126     brouard  5752:     
                   5753:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   5754:     
                   5755:     printf("%d|",(int)age);fflush(stdout);
                   5756:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5757:     
                   5758:     /* Computing expectancies */
                   5759:     for(i=1; i<=nlstate;i++)
                   5760:       for(j=1; j<=nlstate;j++)
                   5761:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5762:          eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
                   5763:          
                   5764:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
                   5765: 
                   5766:        }
                   5767: 
                   5768:     fprintf(ficreseij,"%3.0f",age );
                   5769:     for(i=1; i<=nlstate;i++){
                   5770:       eip=0;
                   5771:       for(j=1; j<=nlstate;j++){
                   5772:        eip +=eij[i][j][(int)age];
                   5773:        fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
                   5774:       }
                   5775:       fprintf(ficreseij,"%9.4f", eip );
                   5776:     }
                   5777:     fprintf(ficreseij,"\n");
                   5778:     
                   5779:   }
                   5780:   free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5781:   printf("\n");
                   5782:   fprintf(ficlog,"\n");
                   5783:   
                   5784: }
                   5785: 
1.235     brouard  5786:  void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[], int nres )
1.126     brouard  5787: 
                   5788: {
                   5789:   /* Covariances of health expectancies eij and of total life expectancies according
1.222     brouard  5790:      to initial status i, ei. .
1.126     brouard  5791:   */
                   5792:   int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
                   5793:   int nhstepma, nstepma; /* Decreasing with age */
                   5794:   double age, agelim, hf;
                   5795:   double ***p3matp, ***p3matm, ***varhe;
                   5796:   double **dnewm,**doldm;
                   5797:   double *xp, *xm;
                   5798:   double **gp, **gm;
                   5799:   double ***gradg, ***trgradg;
                   5800:   int theta;
                   5801: 
                   5802:   double eip, vip;
                   5803: 
                   5804:   varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
                   5805:   xp=vector(1,npar);
                   5806:   xm=vector(1,npar);
                   5807:   dnewm=matrix(1,nlstate*nlstate,1,npar);
                   5808:   doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
                   5809:   
                   5810:   pstamp(ficresstdeij);
                   5811:   fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
                   5812:   fprintf(ficresstdeij,"# Age");
                   5813:   for(i=1; i<=nlstate;i++){
                   5814:     for(j=1; j<=nlstate;j++)
                   5815:       fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
                   5816:     fprintf(ficresstdeij," e%1d. ",i);
                   5817:   }
                   5818:   fprintf(ficresstdeij,"\n");
                   5819: 
                   5820:   pstamp(ficrescveij);
                   5821:   fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
                   5822:   fprintf(ficrescveij,"# Age");
                   5823:   for(i=1; i<=nlstate;i++)
                   5824:     for(j=1; j<=nlstate;j++){
                   5825:       cptj= (j-1)*nlstate+i;
                   5826:       for(i2=1; i2<=nlstate;i2++)
                   5827:        for(j2=1; j2<=nlstate;j2++){
                   5828:          cptj2= (j2-1)*nlstate+i2;
                   5829:          if(cptj2 <= cptj)
                   5830:            fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
                   5831:        }
                   5832:     }
                   5833:   fprintf(ficrescveij,"\n");
                   5834:   
                   5835:   if(estepm < stepm){
                   5836:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   5837:   }
                   5838:   else  hstepm=estepm;   
                   5839:   /* We compute the life expectancy from trapezoids spaced every estepm months
                   5840:    * This is mainly to measure the difference between two models: for example
                   5841:    * if stepm=24 months pijx are given only every 2 years and by summing them
                   5842:    * we are calculating an estimate of the Life Expectancy assuming a linear 
                   5843:    * progression in between and thus overestimating or underestimating according
                   5844:    * to the curvature of the survival function. If, for the same date, we 
                   5845:    * estimate the model with stepm=1 month, we can keep estepm to 24 months
                   5846:    * to compare the new estimate of Life expectancy with the same linear 
                   5847:    * hypothesis. A more precise result, taking into account a more precise
                   5848:    * curvature will be obtained if estepm is as small as stepm. */
                   5849: 
                   5850:   /* For example we decided to compute the life expectancy with the smallest unit */
                   5851:   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   5852:      nhstepm is the number of hstepm from age to agelim 
                   5853:      nstepm is the number of stepm from age to agelin. 
                   5854:      Look at hpijx to understand the reason of that which relies in memory size
                   5855:      and note for a fixed period like estepm months */
                   5856:   /* We decided (b) to get a life expectancy respecting the most precise curvature of the
                   5857:      survival function given by stepm (the optimization length). Unfortunately it
                   5858:      means that if the survival funtion is printed only each two years of age and if
                   5859:      you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   5860:      results. So we changed our mind and took the option of the best precision.
                   5861:   */
                   5862:   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   5863: 
                   5864:   /* If stepm=6 months */
                   5865:   /* nhstepm age range expressed in number of stepm */
                   5866:   agelim=AGESUP;
                   5867:   nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
                   5868:   /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5869:   /* if (stepm >= YEARM) hstepm=1;*/
                   5870:   nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   5871:   
                   5872:   p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5873:   p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5874:   gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
                   5875:   trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
                   5876:   gp=matrix(0,nhstepm,1,nlstate*nlstate);
                   5877:   gm=matrix(0,nhstepm,1,nlstate*nlstate);
                   5878: 
                   5879:   for (age=bage; age<=fage; age ++){ 
                   5880:     nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
                   5881:     /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
                   5882:     /* if (stepm >= YEARM) hstepm=1;*/
                   5883:     nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
1.218     brouard  5884:                
1.126     brouard  5885:     /* If stepm=6 months */
                   5886:     /* Computed by stepm unit matrices, product of hstepma matrices, stored
                   5887:        in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
                   5888:     
                   5889:     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
1.218     brouard  5890:                
1.126     brouard  5891:     /* Computing  Variances of health expectancies */
                   5892:     /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
                   5893:        decrease memory allocation */
                   5894:     for(theta=1; theta <=npar; theta++){
                   5895:       for(i=1; i<=npar; i++){ 
1.222     brouard  5896:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   5897:        xm[i] = x[i] - (i==theta ?delti[theta]:0);
1.126     brouard  5898:       }
1.235     brouard  5899:       hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij, nres);  
                   5900:       hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij, nres);  
1.218     brouard  5901:                        
1.126     brouard  5902:       for(j=1; j<= nlstate; j++){
1.222     brouard  5903:        for(i=1; i<=nlstate; i++){
                   5904:          for(h=0; h<=nhstepm-1; h++){
                   5905:            gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
                   5906:            gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
                   5907:          }
                   5908:        }
1.126     brouard  5909:       }
1.218     brouard  5910:                        
1.126     brouard  5911:       for(ij=1; ij<= nlstate*nlstate; ij++)
1.222     brouard  5912:        for(h=0; h<=nhstepm-1; h++){
                   5913:          gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
                   5914:        }
1.126     brouard  5915:     }/* End theta */
                   5916:     
                   5917:     
                   5918:     for(h=0; h<=nhstepm-1; h++)
                   5919:       for(j=1; j<=nlstate*nlstate;j++)
1.222     brouard  5920:        for(theta=1; theta <=npar; theta++)
                   5921:          trgradg[h][j][theta]=gradg[h][theta][j];
1.126     brouard  5922:     
1.218     brouard  5923:                
1.222     brouard  5924:     for(ij=1;ij<=nlstate*nlstate;ij++)
1.126     brouard  5925:       for(ji=1;ji<=nlstate*nlstate;ji++)
1.222     brouard  5926:        varhe[ij][ji][(int)age] =0.;
1.218     brouard  5927:                
1.222     brouard  5928:     printf("%d|",(int)age);fflush(stdout);
                   5929:     fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
                   5930:     for(h=0;h<=nhstepm-1;h++){
1.126     brouard  5931:       for(k=0;k<=nhstepm-1;k++){
1.222     brouard  5932:        matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
                   5933:        matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
                   5934:        for(ij=1;ij<=nlstate*nlstate;ij++)
                   5935:          for(ji=1;ji<=nlstate*nlstate;ji++)
                   5936:            varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
1.126     brouard  5937:       }
                   5938:     }
1.218     brouard  5939:                
1.126     brouard  5940:     /* Computing expectancies */
1.235     brouard  5941:     hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij,nres);  
1.126     brouard  5942:     for(i=1; i<=nlstate;i++)
                   5943:       for(j=1; j<=nlstate;j++)
1.222     brouard  5944:        for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
                   5945:          eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
1.218     brouard  5946:                                        
1.222     brouard  5947:          /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
1.218     brouard  5948:                                        
1.222     brouard  5949:        }
1.269     brouard  5950: 
                   5951:     /* Standard deviation of expectancies ij */                
1.126     brouard  5952:     fprintf(ficresstdeij,"%3.0f",age );
                   5953:     for(i=1; i<=nlstate;i++){
                   5954:       eip=0.;
                   5955:       vip=0.;
                   5956:       for(j=1; j<=nlstate;j++){
1.222     brouard  5957:        eip += eij[i][j][(int)age];
                   5958:        for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
                   5959:          vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
                   5960:        fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
1.126     brouard  5961:       }
                   5962:       fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
                   5963:     }
                   5964:     fprintf(ficresstdeij,"\n");
1.218     brouard  5965:                
1.269     brouard  5966:     /* Variance of expectancies ij */          
1.126     brouard  5967:     fprintf(ficrescveij,"%3.0f",age );
                   5968:     for(i=1; i<=nlstate;i++)
                   5969:       for(j=1; j<=nlstate;j++){
1.222     brouard  5970:        cptj= (j-1)*nlstate+i;
                   5971:        for(i2=1; i2<=nlstate;i2++)
                   5972:          for(j2=1; j2<=nlstate;j2++){
                   5973:            cptj2= (j2-1)*nlstate+i2;
                   5974:            if(cptj2 <= cptj)
                   5975:              fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
                   5976:          }
1.126     brouard  5977:       }
                   5978:     fprintf(ficrescveij,"\n");
1.218     brouard  5979:                
1.126     brouard  5980:   }
                   5981:   free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
                   5982:   free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
                   5983:   free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
                   5984:   free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
                   5985:   free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5986:   free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   5987:   printf("\n");
                   5988:   fprintf(ficlog,"\n");
1.218     brouard  5989:        
1.126     brouard  5990:   free_vector(xm,1,npar);
                   5991:   free_vector(xp,1,npar);
                   5992:   free_matrix(dnewm,1,nlstate*nlstate,1,npar);
                   5993:   free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
                   5994:   free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
                   5995: }
1.218     brouard  5996:  
1.126     brouard  5997: /************ Variance ******************/
1.235     brouard  5998:  void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[], int nres)
1.218     brouard  5999:  {
1.279     brouard  6000:    /** Variance of health expectancies 
                   6001:     *  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);
                   6002:     * double **newm;
                   6003:     * int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav) 
                   6004:     */
1.218     brouard  6005:   
                   6006:    /* int movingaverage(); */
                   6007:    double **dnewm,**doldm;
                   6008:    double **dnewmp,**doldmp;
                   6009:    int i, j, nhstepm, hstepm, h, nstepm ;
1.288     brouard  6010:    int first=0;
1.218     brouard  6011:    int k;
                   6012:    double *xp;
1.279     brouard  6013:    double **gp, **gm;  /**< for var eij */
                   6014:    double ***gradg, ***trgradg; /**< for var eij */
                   6015:    double **gradgp, **trgradgp; /**< for var p point j */
                   6016:    double *gpp, *gmp; /**< for var p point j */
                   6017:    double **varppt; /**< for var p point j nlstate to nlstate+ndeath */
1.218     brouard  6018:    double ***p3mat;
                   6019:    double age,agelim, hf;
                   6020:    /* double ***mobaverage; */
                   6021:    int theta;
                   6022:    char digit[4];
                   6023:    char digitp[25];
                   6024: 
                   6025:    char fileresprobmorprev[FILENAMELENGTH];
                   6026: 
                   6027:    if(popbased==1){
                   6028:      if(mobilav!=0)
                   6029:        strcpy(digitp,"-POPULBASED-MOBILAV_");
                   6030:      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
                   6031:    }
                   6032:    else 
                   6033:      strcpy(digitp,"-STABLBASED_");
1.126     brouard  6034: 
1.218     brouard  6035:    /* if (mobilav!=0) { */
                   6036:    /*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6037:    /*   if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){ */
                   6038:    /*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); */
                   6039:    /*     printf(" Error in movingaverage mobilav=%d\n",mobilav); */
                   6040:    /*   } */
                   6041:    /* } */
                   6042: 
                   6043:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
                   6044:    sprintf(digit,"%-d",ij);
                   6045:    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
                   6046:    strcat(fileresprobmorprev,digit); /* Tvar to be done */
                   6047:    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
                   6048:    strcat(fileresprobmorprev,fileresu);
                   6049:    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
                   6050:      printf("Problem with resultfile: %s\n", fileresprobmorprev);
                   6051:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
                   6052:    }
                   6053:    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6054:    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
                   6055:    pstamp(ficresprobmorprev);
                   6056:    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
1.238     brouard  6057:    fprintf(ficresprobmorprev,"# Selected quantitative variables and dummies");
                   6058:    for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   6059:      fprintf(ficresprobmorprev," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   6060:    }
                   6061:    for(j=1;j<=cptcoveff;j++) 
                   6062:      fprintf(ficresprobmorprev,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(ij,j)]);
                   6063:    fprintf(ficresprobmorprev,"\n");
                   6064: 
1.218     brouard  6065:    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
                   6066:    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6067:      fprintf(ficresprobmorprev," p.%-d SE",j);
                   6068:      for(i=1; i<=nlstate;i++)
                   6069:        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
                   6070:    }  
                   6071:    fprintf(ficresprobmorprev,"\n");
                   6072:   
                   6073:    fprintf(ficgp,"\n# Routine varevsij");
                   6074:    fprintf(ficgp,"\nunset title \n");
                   6075:    /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
                   6076:    fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
                   6077:    fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
1.279     brouard  6078: 
1.218     brouard  6079:    varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6080:    pstamp(ficresvij);
                   6081:    fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
                   6082:    if(popbased==1)
                   6083:      fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
                   6084:    else
                   6085:      fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
                   6086:    fprintf(ficresvij,"# Age");
                   6087:    for(i=1; i<=nlstate;i++)
                   6088:      for(j=1; j<=nlstate;j++)
                   6089:        fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
                   6090:    fprintf(ficresvij,"\n");
                   6091: 
                   6092:    xp=vector(1,npar);
                   6093:    dnewm=matrix(1,nlstate,1,npar);
                   6094:    doldm=matrix(1,nlstate,1,nlstate);
                   6095:    dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
                   6096:    doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6097: 
                   6098:    gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
                   6099:    gpp=vector(nlstate+1,nlstate+ndeath);
                   6100:    gmp=vector(nlstate+1,nlstate+ndeath);
                   6101:    trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
1.126     brouard  6102:   
1.218     brouard  6103:    if(estepm < stepm){
                   6104:      printf ("Problem %d lower than %d\n",estepm, stepm);
                   6105:    }
                   6106:    else  hstepm=estepm;   
                   6107:    /* For example we decided to compute the life expectancy with the smallest unit */
                   6108:    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
                   6109:       nhstepm is the number of hstepm from age to agelim 
                   6110:       nstepm is the number of stepm from age to agelim. 
                   6111:       Look at function hpijx to understand why because of memory size limitations, 
                   6112:       we decided (b) to get a life expectancy respecting the most precise curvature of the
                   6113:       survival function given by stepm (the optimization length). Unfortunately it
                   6114:       means that if the survival funtion is printed every two years of age and if
                   6115:       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
                   6116:       results. So we changed our mind and took the option of the best precision.
                   6117:    */
                   6118:    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
                   6119:    agelim = AGESUP;
                   6120:    for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6121:      nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6122:      nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
                   6123:      p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6124:      gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
                   6125:      gp=matrix(0,nhstepm,1,nlstate);
                   6126:      gm=matrix(0,nhstepm,1,nlstate);
                   6127:                
                   6128:                
                   6129:      for(theta=1; theta <=npar; theta++){
                   6130:        for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
                   6131:         xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6132:        }
1.279     brouard  6133:        /**< Computes the prevalence limit with parameter theta shifted of delta up to ftolpl precision and 
                   6134:        * returns into prlim .
1.288     brouard  6135:        */
1.242     brouard  6136:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.279     brouard  6137: 
                   6138:        /* If popbased = 1 we use crossection prevalences. Previous step is useless but prlim is created */
1.218     brouard  6139:        if (popbased==1) {
                   6140:         if(mobilav ==0){
                   6141:           for(i=1; i<=nlstate;i++)
                   6142:             prlim[i][i]=probs[(int)age][i][ij];
                   6143:         }else{ /* mobilav */ 
                   6144:           for(i=1; i<=nlstate;i++)
                   6145:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6146:         }
                   6147:        }
1.295     brouard  6148:        /**< Computes the shifted transition matrix \f$ {}{h}_p^{ij}x\f$ at horizon h.
1.279     brouard  6149:        */                      
                   6150:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  /* Returns p3mat[i][j][h] for h=0 to nhstepm */
1.292     brouard  6151:        /**< And for each alive state j, sums over i \f$ w^i_x {}{h}_p^{ij}x\f$, which are the probability
1.279     brouard  6152:        * at horizon h in state j including mortality.
                   6153:        */
1.218     brouard  6154:        for(j=1; j<= nlstate; j++){
                   6155:         for(h=0; h<=nhstepm; h++){
                   6156:           for(i=1, gp[h][j]=0.;i<=nlstate;i++)
                   6157:             gp[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6158:         }
                   6159:        }
1.279     brouard  6160:        /* Next for computing shifted+ probability of death (h=1 means
1.218     brouard  6161:          computed over hstepm matrices product = hstepm*stepm months) 
1.279     brouard  6162:          as a weighted average of prlim(i) * p(i,j) p.3=w1*p13 + w2*p23 .
1.218     brouard  6163:        */
                   6164:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6165:         for(i=1,gpp[j]=0.; i<= nlstate; i++)
                   6166:           gpp[j] += prlim[i][i]*p3mat[i][j][1];
1.279     brouard  6167:        }
                   6168:        
                   6169:        /* Again with minus shift */
1.218     brouard  6170:                        
                   6171:        for(i=1; i<=npar; i++) /* Computes gradient x - delta */
                   6172:         xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6173: 
1.242     brouard  6174:        prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij, nres);
1.218     brouard  6175:                        
                   6176:        if (popbased==1) {
                   6177:         if(mobilav ==0){
                   6178:           for(i=1; i<=nlstate;i++)
                   6179:             prlim[i][i]=probs[(int)age][i][ij];
                   6180:         }else{ /* mobilav */ 
                   6181:           for(i=1; i<=nlstate;i++)
                   6182:             prlim[i][i]=mobaverage[(int)age][i][ij];
                   6183:         }
                   6184:        }
                   6185:                        
1.235     brouard  6186:        hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij,nres);  
1.218     brouard  6187:                        
                   6188:        for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
                   6189:         for(h=0; h<=nhstepm; h++){
                   6190:           for(i=1, gm[h][j]=0.;i<=nlstate;i++)
                   6191:             gm[h][j] += prlim[i][i]*p3mat[i][j][h];
                   6192:         }
                   6193:        }
                   6194:        /* This for computing probability of death (h=1 means
                   6195:          computed over hstepm matrices product = hstepm*stepm months) 
                   6196:          as a weighted average of prlim.
                   6197:        */
                   6198:        for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6199:         for(i=1,gmp[j]=0.; i<= nlstate; i++)
                   6200:           gmp[j] += prlim[i][i]*p3mat[i][j][1];
                   6201:        }    
1.279     brouard  6202:        /* end shifting computations */
                   6203: 
                   6204:        /**< Computing gradient matrix at horizon h 
                   6205:        */
1.218     brouard  6206:        for(j=1; j<= nlstate; j++) /* vareij */
                   6207:         for(h=0; h<=nhstepm; h++){
                   6208:           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
                   6209:         }
1.279     brouard  6210:        /**< Gradient of overall mortality p.3 (or p.j) 
                   6211:        */
                   6212:        for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu mortality from j */
1.218     brouard  6213:         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
                   6214:        }
                   6215:                        
                   6216:      } /* End theta */
1.279     brouard  6217:      
                   6218:      /* We got the gradient matrix for each theta and state j */               
1.218     brouard  6219:      trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
                   6220:                
                   6221:      for(h=0; h<=nhstepm; h++) /* veij */
                   6222:        for(j=1; j<=nlstate;j++)
                   6223:         for(theta=1; theta <=npar; theta++)
                   6224:           trgradg[h][j][theta]=gradg[h][theta][j];
                   6225:                
                   6226:      for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
                   6227:        for(theta=1; theta <=npar; theta++)
                   6228:         trgradgp[j][theta]=gradgp[theta][j];
1.279     brouard  6229:      /**< as well as its transposed matrix 
                   6230:       */               
1.218     brouard  6231:                
                   6232:      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
                   6233:      for(i=1;i<=nlstate;i++)
                   6234:        for(j=1;j<=nlstate;j++)
                   6235:         vareij[i][j][(int)age] =0.;
1.279     brouard  6236: 
                   6237:      /* Computing trgradg by matcov by gradg at age and summing over h
                   6238:       * and k (nhstepm) formula 15 of article
                   6239:       * Lievre-Brouard-Heathcote
                   6240:       */
                   6241:      
1.218     brouard  6242:      for(h=0;h<=nhstepm;h++){
                   6243:        for(k=0;k<=nhstepm;k++){
                   6244:         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
                   6245:         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
                   6246:         for(i=1;i<=nlstate;i++)
                   6247:           for(j=1;j<=nlstate;j++)
                   6248:             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
                   6249:        }
                   6250:      }
                   6251:                
1.279     brouard  6252:      /* pptj is p.3 or p.j = trgradgp by cov by gradgp, variance of
                   6253:       * p.j overall mortality formula 49 but computed directly because
                   6254:       * we compute the grad (wix pijx) instead of grad (pijx),even if
                   6255:       * wix is independent of theta.
                   6256:       */
1.218     brouard  6257:      matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
                   6258:      matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
                   6259:      for(j=nlstate+1;j<=nlstate+ndeath;j++)
                   6260:        for(i=nlstate+1;i<=nlstate+ndeath;i++)
                   6261:         varppt[j][i]=doldmp[j][i];
                   6262:      /* end ppptj */
                   6263:      /*  x centered again */
                   6264:                
1.242     brouard  6265:      prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij, nres);
1.218     brouard  6266:                
                   6267:      if (popbased==1) {
                   6268:        if(mobilav ==0){
                   6269:         for(i=1; i<=nlstate;i++)
                   6270:           prlim[i][i]=probs[(int)age][i][ij];
                   6271:        }else{ /* mobilav */ 
                   6272:         for(i=1; i<=nlstate;i++)
                   6273:           prlim[i][i]=mobaverage[(int)age][i][ij];
                   6274:        }
                   6275:      }
                   6276:                
                   6277:      /* This for computing probability of death (h=1 means
                   6278:        computed over hstepm (estepm) matrices product = hstepm*stepm months) 
                   6279:        as a weighted average of prlim.
                   6280:      */
1.235     brouard  6281:      hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij, nres);  
1.218     brouard  6282:      for(j=nlstate+1;j<=nlstate+ndeath;j++){
                   6283:        for(i=1,gmp[j]=0.;i<= nlstate; i++) 
                   6284:         gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
                   6285:      }    
                   6286:      /* end probability of death */
                   6287:                
                   6288:      fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
                   6289:      for(j=nlstate+1; j<=(nlstate+ndeath);j++){
                   6290:        fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
                   6291:        for(i=1; i<=nlstate;i++){
                   6292:         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
                   6293:        }
                   6294:      } 
                   6295:      fprintf(ficresprobmorprev,"\n");
                   6296:                
                   6297:      fprintf(ficresvij,"%.0f ",age );
                   6298:      for(i=1; i<=nlstate;i++)
                   6299:        for(j=1; j<=nlstate;j++){
                   6300:         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
                   6301:        }
                   6302:      fprintf(ficresvij,"\n");
                   6303:      free_matrix(gp,0,nhstepm,1,nlstate);
                   6304:      free_matrix(gm,0,nhstepm,1,nlstate);
                   6305:      free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
                   6306:      free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
                   6307:      free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   6308:    } /* End age */
                   6309:    free_vector(gpp,nlstate+1,nlstate+ndeath);
                   6310:    free_vector(gmp,nlstate+1,nlstate+ndeath);
                   6311:    free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
                   6312:    free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
                   6313:    /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
                   6314:    fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
                   6315:    /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
                   6316:    fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
                   6317:    fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6318:    /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
                   6319:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6320:    /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
                   6321:    fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
                   6322:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
                   6323:    fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
                   6324:    fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
                   6325:    fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
                   6326:    /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
1.126     brouard  6327:     */
1.218     brouard  6328:    /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
                   6329:    fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
1.126     brouard  6330: 
1.218     brouard  6331:    free_vector(xp,1,npar);
                   6332:    free_matrix(doldm,1,nlstate,1,nlstate);
                   6333:    free_matrix(dnewm,1,nlstate,1,npar);
                   6334:    free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6335:    free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
                   6336:    free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
                   6337:    /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   6338:    fclose(ficresprobmorprev);
                   6339:    fflush(ficgp);
                   6340:    fflush(fichtm); 
                   6341:  }  /* end varevsij */
1.126     brouard  6342: 
                   6343: /************ Variance of prevlim ******************/
1.269     brouard  6344:  void varprevlim(char fileresvpl[], FILE *ficresvpl, double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[], int nres)
1.126     brouard  6345: {
1.205     brouard  6346:   /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
1.126     brouard  6347:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
1.164     brouard  6348: 
1.268     brouard  6349:   double **dnewmpar,**doldm;
1.126     brouard  6350:   int i, j, nhstepm, hstepm;
                   6351:   double *xp;
                   6352:   double *gp, *gm;
                   6353:   double **gradg, **trgradg;
1.208     brouard  6354:   double **mgm, **mgp;
1.126     brouard  6355:   double age,agelim;
                   6356:   int theta;
                   6357:   
                   6358:   pstamp(ficresvpl);
1.288     brouard  6359:   fprintf(ficresvpl,"# Standard deviation of period (forward stable) prevalences \n");
1.241     brouard  6360:   fprintf(ficresvpl,"# Age ");
                   6361:   if(nresult >=1)
                   6362:     fprintf(ficresvpl," Result# ");
1.126     brouard  6363:   for(i=1; i<=nlstate;i++)
                   6364:       fprintf(ficresvpl," %1d-%1d",i,i);
                   6365:   fprintf(ficresvpl,"\n");
                   6366: 
                   6367:   xp=vector(1,npar);
1.268     brouard  6368:   dnewmpar=matrix(1,nlstate,1,npar);
1.126     brouard  6369:   doldm=matrix(1,nlstate,1,nlstate);
                   6370:   
                   6371:   hstepm=1*YEARM; /* Every year of age */
                   6372:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6373:   agelim = AGESUP;
                   6374:   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
                   6375:     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6376:     if (stepm >= YEARM) hstepm=1;
                   6377:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6378:     gradg=matrix(1,npar,1,nlstate);
1.208     brouard  6379:     mgp=matrix(1,npar,1,nlstate);
                   6380:     mgm=matrix(1,npar,1,nlstate);
1.126     brouard  6381:     gp=vector(1,nlstate);
                   6382:     gm=vector(1,nlstate);
                   6383: 
                   6384:     for(theta=1; theta <=npar; theta++){
                   6385:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6386:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6387:       }
1.288     brouard  6388:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6389:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6390:       /* else */
                   6391:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6392:       for(i=1;i<=nlstate;i++){
1.126     brouard  6393:        gp[i] = prlim[i][i];
1.208     brouard  6394:        mgp[theta][i] = prlim[i][i];
                   6395:       }
1.126     brouard  6396:       for(i=1; i<=npar; i++) /* Computes gradient */
                   6397:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
1.288     brouard  6398:       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ) */
                   6399:       /*       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres); */
                   6400:       /* else */
                   6401:       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij,nres);
1.208     brouard  6402:       for(i=1;i<=nlstate;i++){
1.126     brouard  6403:        gm[i] = prlim[i][i];
1.208     brouard  6404:        mgm[theta][i] = prlim[i][i];
                   6405:       }
1.126     brouard  6406:       for(i=1;i<=nlstate;i++)
                   6407:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
1.209     brouard  6408:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
1.126     brouard  6409:     } /* End theta */
                   6410: 
                   6411:     trgradg =matrix(1,nlstate,1,npar);
                   6412: 
                   6413:     for(j=1; j<=nlstate;j++)
                   6414:       for(theta=1; theta <=npar; theta++)
                   6415:        trgradg[j][theta]=gradg[theta][j];
1.209     brouard  6416:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6417:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6418:     /*   for(j=1; j<=nlstate;j++){ */
                   6419:     /*         printf(" %d ",j); */
                   6420:     /*         for(theta=1; theta <=npar; theta++) */
                   6421:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6422:     /*         printf("\n "); */
                   6423:     /*   } */
                   6424:     /* } */
                   6425:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6426:     /*   printf("\n gradg %d ",(int)age); */
                   6427:     /*   for(j=1; j<=nlstate;j++){ */
                   6428:     /*         printf("%d ",j); */
                   6429:     /*         for(theta=1; theta <=npar; theta++) */
                   6430:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6431:     /*         printf("\n "); */
                   6432:     /*   } */
                   6433:     /* } */
1.126     brouard  6434: 
                   6435:     for(i=1;i<=nlstate;i++)
                   6436:       varpl[i][(int)age] =0.;
1.209     brouard  6437:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
1.268     brouard  6438:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6439:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6440:     }else{
1.268     brouard  6441:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6442:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
1.205     brouard  6443:     }
1.126     brouard  6444:     for(i=1;i<=nlstate;i++)
                   6445:       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6446: 
                   6447:     fprintf(ficresvpl,"%.0f ",age );
1.241     brouard  6448:     if(nresult >=1)
                   6449:       fprintf(ficresvpl,"%d ",nres );
1.288     brouard  6450:     for(i=1; i<=nlstate;i++){
1.126     brouard  6451:       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
1.288     brouard  6452:       /* for(j=1;j<=nlstate;j++) */
                   6453:       /*       fprintf(ficresvpl," %d %.5f ",j,prlim[j][i]); */
                   6454:     }
1.126     brouard  6455:     fprintf(ficresvpl,"\n");
                   6456:     free_vector(gp,1,nlstate);
                   6457:     free_vector(gm,1,nlstate);
1.208     brouard  6458:     free_matrix(mgm,1,npar,1,nlstate);
                   6459:     free_matrix(mgp,1,npar,1,nlstate);
1.126     brouard  6460:     free_matrix(gradg,1,npar,1,nlstate);
                   6461:     free_matrix(trgradg,1,nlstate,1,npar);
                   6462:   } /* End age */
                   6463: 
                   6464:   free_vector(xp,1,npar);
                   6465:   free_matrix(doldm,1,nlstate,1,npar);
1.268     brouard  6466:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
                   6467: 
                   6468: }
                   6469: 
                   6470: 
                   6471: /************ Variance of backprevalence limit ******************/
1.269     brouard  6472:  void varbrevlim(char fileresvbl[], FILE  *ficresvbl, double **varbpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **bprlim, double ftolpl, int mobilavproj, int *ncvyearp, int ij, char strstart[], int nres)
1.268     brouard  6473: {
                   6474:   /* Variance of backward prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
                   6475:   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
                   6476: 
                   6477:   double **dnewmpar,**doldm;
                   6478:   int i, j, nhstepm, hstepm;
                   6479:   double *xp;
                   6480:   double *gp, *gm;
                   6481:   double **gradg, **trgradg;
                   6482:   double **mgm, **mgp;
                   6483:   double age,agelim;
                   6484:   int theta;
                   6485:   
                   6486:   pstamp(ficresvbl);
                   6487:   fprintf(ficresvbl,"# Standard deviation of back (stable) prevalences \n");
                   6488:   fprintf(ficresvbl,"# Age ");
                   6489:   if(nresult >=1)
                   6490:     fprintf(ficresvbl," Result# ");
                   6491:   for(i=1; i<=nlstate;i++)
                   6492:       fprintf(ficresvbl," %1d-%1d",i,i);
                   6493:   fprintf(ficresvbl,"\n");
                   6494: 
                   6495:   xp=vector(1,npar);
                   6496:   dnewmpar=matrix(1,nlstate,1,npar);
                   6497:   doldm=matrix(1,nlstate,1,nlstate);
                   6498:   
                   6499:   hstepm=1*YEARM; /* Every year of age */
                   6500:   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
                   6501:   agelim = AGEINF;
                   6502:   for (age=fage; age>=bage; age --){ /* If stepm=6 months */
                   6503:     nhstepm=(int) rint((age-agelim)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   6504:     if (stepm >= YEARM) hstepm=1;
                   6505:     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   6506:     gradg=matrix(1,npar,1,nlstate);
                   6507:     mgp=matrix(1,npar,1,nlstate);
                   6508:     mgm=matrix(1,npar,1,nlstate);
                   6509:     gp=vector(1,nlstate);
                   6510:     gm=vector(1,nlstate);
                   6511: 
                   6512:     for(theta=1; theta <=npar; theta++){
                   6513:       for(i=1; i<=npar; i++){ /* Computes gradient */
                   6514:        xp[i] = x[i] + (i==theta ?delti[theta]:0);
                   6515:       }
                   6516:       if(mobilavproj > 0 )
                   6517:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6518:       else
                   6519:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6520:       for(i=1;i<=nlstate;i++){
                   6521:        gp[i] = bprlim[i][i];
                   6522:        mgp[theta][i] = bprlim[i][i];
                   6523:       }
                   6524:      for(i=1; i<=npar; i++) /* Computes gradient */
                   6525:        xp[i] = x[i] - (i==theta ?delti[theta]:0);
                   6526:        if(mobilavproj > 0 )
                   6527:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6528:        else
                   6529:        bprevalim(bprlim, mobaverage,nlstate,xp,age,ftolpl,ncvyearp,ij,nres);
                   6530:       for(i=1;i<=nlstate;i++){
                   6531:        gm[i] = bprlim[i][i];
                   6532:        mgm[theta][i] = bprlim[i][i];
                   6533:       }
                   6534:       for(i=1;i<=nlstate;i++)
                   6535:        gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
                   6536:       /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
                   6537:     } /* End theta */
                   6538: 
                   6539:     trgradg =matrix(1,nlstate,1,npar);
                   6540: 
                   6541:     for(j=1; j<=nlstate;j++)
                   6542:       for(theta=1; theta <=npar; theta++)
                   6543:        trgradg[j][theta]=gradg[theta][j];
                   6544:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6545:     /*   printf("\nmgm mgp %d ",(int)age); */
                   6546:     /*   for(j=1; j<=nlstate;j++){ */
                   6547:     /*         printf(" %d ",j); */
                   6548:     /*         for(theta=1; theta <=npar; theta++) */
                   6549:     /*           printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
                   6550:     /*         printf("\n "); */
                   6551:     /*   } */
                   6552:     /* } */
                   6553:     /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
                   6554:     /*   printf("\n gradg %d ",(int)age); */
                   6555:     /*   for(j=1; j<=nlstate;j++){ */
                   6556:     /*         printf("%d ",j); */
                   6557:     /*         for(theta=1; theta <=npar; theta++) */
                   6558:     /*           printf("%d %lf ",theta,gradg[theta][j]); */
                   6559:     /*         printf("\n "); */
                   6560:     /*   } */
                   6561:     /* } */
                   6562: 
                   6563:     for(i=1;i<=nlstate;i++)
                   6564:       varbpl[i][(int)age] =0.;
                   6565:     if((int)age==79 ||(int)age== 80  ||(int)age== 81){
                   6566:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6567:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6568:     }else{
                   6569:     matprod2(dnewmpar,trgradg,1,nlstate,1,npar,1,npar,matcov);
                   6570:     matprod2(doldm,dnewmpar,1,nlstate,1,npar,1,nlstate,gradg);
                   6571:     }
                   6572:     for(i=1;i<=nlstate;i++)
                   6573:       varbpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
                   6574: 
                   6575:     fprintf(ficresvbl,"%.0f ",age );
                   6576:     if(nresult >=1)
                   6577:       fprintf(ficresvbl,"%d ",nres );
                   6578:     for(i=1; i<=nlstate;i++)
                   6579:       fprintf(ficresvbl," %.5f (%.5f)",bprlim[i][i],sqrt(varbpl[i][(int)age]));
                   6580:     fprintf(ficresvbl,"\n");
                   6581:     free_vector(gp,1,nlstate);
                   6582:     free_vector(gm,1,nlstate);
                   6583:     free_matrix(mgm,1,npar,1,nlstate);
                   6584:     free_matrix(mgp,1,npar,1,nlstate);
                   6585:     free_matrix(gradg,1,npar,1,nlstate);
                   6586:     free_matrix(trgradg,1,nlstate,1,npar);
                   6587:   } /* End age */
                   6588: 
                   6589:   free_vector(xp,1,npar);
                   6590:   free_matrix(doldm,1,nlstate,1,npar);
                   6591:   free_matrix(dnewmpar,1,nlstate,1,nlstate);
1.126     brouard  6592: 
                   6593: }
                   6594: 
                   6595: /************ Variance of one-step probabilities  ******************/
                   6596: void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
1.222     brouard  6597:  {
                   6598:    int i, j=0,  k1, l1, tj;
                   6599:    int k2, l2, j1,  z1;
                   6600:    int k=0, l;
                   6601:    int first=1, first1, first2;
                   6602:    double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
                   6603:    double **dnewm,**doldm;
                   6604:    double *xp;
                   6605:    double *gp, *gm;
                   6606:    double **gradg, **trgradg;
                   6607:    double **mu;
                   6608:    double age, cov[NCOVMAX+1];
                   6609:    double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
                   6610:    int theta;
                   6611:    char fileresprob[FILENAMELENGTH];
                   6612:    char fileresprobcov[FILENAMELENGTH];
                   6613:    char fileresprobcor[FILENAMELENGTH];
                   6614:    double ***varpij;
                   6615: 
                   6616:    strcpy(fileresprob,"PROB_"); 
                   6617:    strcat(fileresprob,fileres);
                   6618:    if((ficresprob=fopen(fileresprob,"w"))==NULL) {
                   6619:      printf("Problem with resultfile: %s\n", fileresprob);
                   6620:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
                   6621:    }
                   6622:    strcpy(fileresprobcov,"PROBCOV_"); 
                   6623:    strcat(fileresprobcov,fileresu);
                   6624:    if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
                   6625:      printf("Problem with resultfile: %s\n", fileresprobcov);
                   6626:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
                   6627:    }
                   6628:    strcpy(fileresprobcor,"PROBCOR_"); 
                   6629:    strcat(fileresprobcor,fileresu);
                   6630:    if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
                   6631:      printf("Problem with resultfile: %s\n", fileresprobcor);
                   6632:      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
                   6633:    }
                   6634:    printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6635:    fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
                   6636:    printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6637:    fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
                   6638:    printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6639:    fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
                   6640:    pstamp(ficresprob);
                   6641:    fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
                   6642:    fprintf(ficresprob,"# Age");
                   6643:    pstamp(ficresprobcov);
                   6644:    fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
                   6645:    fprintf(ficresprobcov,"# Age");
                   6646:    pstamp(ficresprobcor);
                   6647:    fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
                   6648:    fprintf(ficresprobcor,"# Age");
1.126     brouard  6649: 
                   6650: 
1.222     brouard  6651:    for(i=1; i<=nlstate;i++)
                   6652:      for(j=1; j<=(nlstate+ndeath);j++){
                   6653:        fprintf(ficresprob," p%1d-%1d (SE)",i,j);
                   6654:        fprintf(ficresprobcov," p%1d-%1d ",i,j);
                   6655:        fprintf(ficresprobcor," p%1d-%1d ",i,j);
                   6656:      }  
                   6657:    /* fprintf(ficresprob,"\n");
                   6658:       fprintf(ficresprobcov,"\n");
                   6659:       fprintf(ficresprobcor,"\n");
                   6660:    */
                   6661:    xp=vector(1,npar);
                   6662:    dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6663:    doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6664:    mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
                   6665:    varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
                   6666:    first=1;
                   6667:    fprintf(ficgp,"\n# Routine varprob");
                   6668:    fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
                   6669:    fprintf(fichtm,"\n");
                   6670: 
1.288     brouard  6671:    fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back. File %s</li>\n",optionfilehtmcov,optionfilehtmcov);
1.222     brouard  6672:    fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
                   6673:    fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
1.126     brouard  6674: and drawn. It helps understanding how is the covariance between two incidences.\
                   6675:  They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
1.222     brouard  6676:    fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
1.126     brouard  6677: It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
                   6678: would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
                   6679: standard deviations wide on each axis. <br>\
                   6680:  Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
                   6681:  and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
                   6682: To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
                   6683: 
1.222     brouard  6684:    cov[1]=1;
                   6685:    /* tj=cptcoveff; */
1.225     brouard  6686:    tj = (int) pow(2,cptcoveff);
1.222     brouard  6687:    if (cptcovn<1) {tj=1;ncodemax[1]=1;}
                   6688:    j1=0;
1.224     brouard  6689:    for(j1=1; j1<=tj;j1++){  /* For each valid combination of covariates or only once*/
1.222     brouard  6690:      if  (cptcovn>0) {
                   6691:        fprintf(ficresprob, "\n#********** Variable "); 
1.225     brouard  6692:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6693:        fprintf(ficresprob, "**********\n#\n");
                   6694:        fprintf(ficresprobcov, "\n#********** Variable "); 
1.225     brouard  6695:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6696:        fprintf(ficresprobcov, "**********\n#\n");
1.220     brouard  6697:                        
1.222     brouard  6698:        fprintf(ficgp, "\n#********** Variable "); 
1.225     brouard  6699:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6700:        fprintf(ficgp, "**********\n#\n");
1.220     brouard  6701:                        
                   6702:                        
1.222     brouard  6703:        fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
1.225     brouard  6704:        for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6705:        fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  6706:                        
1.222     brouard  6707:        fprintf(ficresprobcor, "\n#********** Variable ");    
1.225     brouard  6708:        for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
1.222     brouard  6709:        fprintf(ficresprobcor, "**********\n#");    
                   6710:        if(invalidvarcomb[j1]){
                   6711:         fprintf(ficgp,"\n#Combination (%d) ignored because no cases \n",j1); 
                   6712:         fprintf(fichtmcov,"\n<h3>Combination (%d) ignored because no cases </h3>\n",j1); 
                   6713:         continue;
                   6714:        }
                   6715:      }
                   6716:      gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
                   6717:      trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
                   6718:      gp=vector(1,(nlstate)*(nlstate+ndeath));
                   6719:      gm=vector(1,(nlstate)*(nlstate+ndeath));
                   6720:      for (age=bage; age<=fage; age ++){ 
                   6721:        cov[2]=age;
                   6722:        if(nagesqr==1)
                   6723:         cov[3]= age*age;
                   6724:        for (k=1; k<=cptcovn;k++) {
                   6725:         cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
                   6726:         /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                   6727:                                                                    * 1  1 1 1 1
                   6728:                                                                    * 2  2 1 1 1
                   6729:                                                                    * 3  1 2 1 1
                   6730:                                                                    */
                   6731:         /* nbcode[1][1]=0 nbcode[1][2]=1;*/
                   6732:        }
                   6733:        /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
                   6734:        for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
                   6735:        for (k=1; k<=cptcovprod;k++)
                   6736:         cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
1.220     brouard  6737:                        
                   6738:                        
1.222     brouard  6739:        for(theta=1; theta <=npar; theta++){
                   6740:         for(i=1; i<=npar; i++)
                   6741:           xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
1.220     brouard  6742:                                
1.222     brouard  6743:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
1.220     brouard  6744:                                
1.222     brouard  6745:         k=0;
                   6746:         for(i=1; i<= (nlstate); i++){
                   6747:           for(j=1; j<=(nlstate+ndeath);j++){
                   6748:             k=k+1;
                   6749:             gp[k]=pmmij[i][j];
                   6750:           }
                   6751:         }
1.220     brouard  6752:                                
1.222     brouard  6753:         for(i=1; i<=npar; i++)
                   6754:           xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
1.220     brouard  6755:                                
1.222     brouard  6756:         pmij(pmmij,cov,ncovmodel,xp,nlstate);
                   6757:         k=0;
                   6758:         for(i=1; i<=(nlstate); i++){
                   6759:           for(j=1; j<=(nlstate+ndeath);j++){
                   6760:             k=k+1;
                   6761:             gm[k]=pmmij[i][j];
                   6762:           }
                   6763:         }
1.220     brouard  6764:                                
1.222     brouard  6765:         for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
                   6766:           gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
                   6767:        }
1.126     brouard  6768: 
1.222     brouard  6769:        for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
                   6770:         for(theta=1; theta <=npar; theta++)
                   6771:           trgradg[j][theta]=gradg[theta][j];
1.220     brouard  6772:                        
1.222     brouard  6773:        matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
                   6774:        matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
1.220     brouard  6775:                        
1.222     brouard  6776:        pmij(pmmij,cov,ncovmodel,x,nlstate);
1.220     brouard  6777:                        
1.222     brouard  6778:        k=0;
                   6779:        for(i=1; i<=(nlstate); i++){
                   6780:         for(j=1; j<=(nlstate+ndeath);j++){
                   6781:           k=k+1;
                   6782:           mu[k][(int) age]=pmmij[i][j];
                   6783:         }
                   6784:        }
                   6785:        for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
                   6786:         for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
                   6787:           varpij[i][j][(int)age] = doldm[i][j];
1.220     brouard  6788:                        
1.222     brouard  6789:        /*printf("\n%d ",(int)age);
                   6790:         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6791:         printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6792:         fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
                   6793:         }*/
1.220     brouard  6794:                        
1.222     brouard  6795:        fprintf(ficresprob,"\n%d ",(int)age);
                   6796:        fprintf(ficresprobcov,"\n%d ",(int)age);
                   6797:        fprintf(ficresprobcor,"\n%d ",(int)age);
1.220     brouard  6798:                        
1.222     brouard  6799:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
                   6800:         fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
                   6801:        for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
                   6802:         fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
                   6803:         fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
                   6804:        }
                   6805:        i=0;
                   6806:        for (k=1; k<=(nlstate);k++){
                   6807:         for (l=1; l<=(nlstate+ndeath);l++){ 
                   6808:           i++;
                   6809:           fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
                   6810:           fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
                   6811:           for (j=1; j<=i;j++){
                   6812:             /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                   6813:             fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                   6814:             fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
                   6815:           }
                   6816:         }
                   6817:        }/* end of loop for state */
                   6818:      } /* end of loop for age */
                   6819:      free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6820:      free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
                   6821:      free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6822:      free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
                   6823:     
                   6824:      /* Confidence intervalle of pij  */
                   6825:      /*
                   6826:        fprintf(ficgp,"\nunset parametric;unset label");
                   6827:        fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
                   6828:        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
                   6829:        fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
                   6830:        fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
                   6831:        fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
                   6832:        fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
                   6833:      */
                   6834:                
                   6835:      /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
                   6836:      first1=1;first2=2;
                   6837:      for (k2=1; k2<=(nlstate);k2++){
                   6838:        for (l2=1; l2<=(nlstate+ndeath);l2++){ 
                   6839:         if(l2==k2) continue;
                   6840:         j=(k2-1)*(nlstate+ndeath)+l2;
                   6841:         for (k1=1; k1<=(nlstate);k1++){
                   6842:           for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                   6843:             if(l1==k1) continue;
                   6844:             i=(k1-1)*(nlstate+ndeath)+l1;
                   6845:             if(i<=j) continue;
                   6846:             for (age=bage; age<=fage; age ++){ 
                   6847:               if ((int)age %5==0){
                   6848:                 v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                   6849:                 v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6850:                 cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                   6851:                 mu1=mu[i][(int) age]/stepm*YEARM ;
                   6852:                 mu2=mu[j][(int) age]/stepm*YEARM;
                   6853:                 c12=cv12/sqrt(v1*v2);
                   6854:                 /* Computing eigen value of matrix of covariance */
                   6855:                 lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6856:                 lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                   6857:                 if ((lc2 <0) || (lc1 <0) ){
                   6858:                   if(first2==1){
                   6859:                     first1=0;
                   6860:                     printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                   6861:                   }
                   6862:                   fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                   6863:                   /* lc1=fabs(lc1); */ /* If we want to have them positive */
                   6864:                   /* lc2=fabs(lc2); */
                   6865:                 }
1.220     brouard  6866:                                                                
1.222     brouard  6867:                 /* Eigen vectors */
1.280     brouard  6868:                 if(1+(v1-lc1)*(v1-lc1)/cv12/cv12 <1.e-5){
                   6869:                   printf(" Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6870:                   fprintf(ficlog," Error sqrt of a negative number: %lf\n",1+(v1-lc1)*(v1-lc1)/cv12/cv12);
                   6871:                   v11=(1./sqrt(fabs(1+(v1-lc1)*(v1-lc1)/cv12/cv12)));
                   6872:                 }else
                   6873:                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
1.222     brouard  6874:                 /*v21=sqrt(1.-v11*v11); *//* error */
                   6875:                 v21=(lc1-v1)/cv12*v11;
                   6876:                 v12=-v21;
                   6877:                 v22=v11;
                   6878:                 tnalp=v21/v11;
                   6879:                 if(first1==1){
                   6880:                   first1=0;
                   6881:                   printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6882:                 }
                   6883:                 fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                   6884:                 /*printf(fignu*/
                   6885:                 /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                   6886:                 /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                   6887:                 if(first==1){
                   6888:                   first=0;
                   6889:                   fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                   6890:                   fprintf(ficgp,"\nset parametric;unset label");
                   6891:                   fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                   6892:                   fprintf(ficgp,"\nset ter svg size 640, 480");
1.266     brouard  6893:                   fprintf(fichtmcov,"\n<p><br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
1.220     brouard  6894:  :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">                                                                                                                                          \
1.201     brouard  6895: %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
1.222     brouard  6896:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,      \
                   6897:                           subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6898:                   fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6899:                   fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                   6900:                   fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6901:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6902:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6903:                   fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",      \
1.280     brouard  6904:                           mu1,std,v11,sqrt(fabs(lc1)),v12,sqrt(fabs(lc2)), \
                   6905:                           mu2,std,v21,sqrt(fabs(lc1)),v22,sqrt(fabs(lc2))); /* For gnuplot only */
1.222     brouard  6906:                 }else{
                   6907:                   first=0;
                   6908:                   fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                   6909:                   fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                   6910:                   fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                   6911:                   fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not", \
1.266     brouard  6912:                           mu1,std,v11,sqrt(lc1),v12,sqrt(fabs(lc2)),   \
                   6913:                           mu2,std,v21,sqrt(lc1),v22,sqrt(fabs(lc2)));
1.222     brouard  6914:                 }/* if first */
                   6915:               } /* age mod 5 */
                   6916:             } /* end loop age */
                   6917:             fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                   6918:             first=1;
                   6919:           } /*l12 */
                   6920:         } /* k12 */
                   6921:        } /*l1 */
                   6922:      }/* k1 */
                   6923:    }  /* loop on combination of covariates j1 */
                   6924:    free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
                   6925:    free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
                   6926:    free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
                   6927:    free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
                   6928:    free_vector(xp,1,npar);
                   6929:    fclose(ficresprob);
                   6930:    fclose(ficresprobcov);
                   6931:    fclose(ficresprobcor);
                   6932:    fflush(ficgp);
                   6933:    fflush(fichtmcov);
                   6934:  }
1.126     brouard  6935: 
                   6936: 
                   6937: /******************* Printing html file ***********/
1.201     brouard  6938: void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  6939:                  int lastpass, int stepm, int weightopt, char model[],\
                   6940:                  int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
1.296     brouard  6941:                  int popforecast, int mobilav, int prevfcast, int mobilavproj, int prevbcast, int estepm , \
                   6942:                  double jprev1, double mprev1,double anprev1, double dateprev1, double dateprojd, double dateback1, \
                   6943:                  double jprev2, double mprev2,double anprev2, double dateprev2, double dateprojf, double dateback2){
1.237     brouard  6944:   int jj1, k1, i1, cpt, k4, nres;
1.126     brouard  6945: 
                   6946:    fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
                   6947:    <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
                   6948: </ul>");
1.237     brouard  6949:    fprintf(fichtm,"<ul><li> model=1+age+%s\n \
                   6950: </ul>", model);
1.214     brouard  6951:    fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n");
                   6952:    fprintf(fichtm,"<li>- Observed frequency between two states (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file)<br/>\n",
                   6953:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTMFR_",".htm"),subdirfext3(optionfilefiname,"PHTMFR_",".htm"));
                   6954:    fprintf(fichtm,"<li> - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> (html file) ",
1.213     brouard  6955:           jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirfext3(optionfilefiname,"PHTM_",".htm"),subdirfext3(optionfilefiname,"PHTM_",".htm"));
                   6956:    fprintf(fichtm,",  <a href=\"%s\">%s</a> (text file) <br>\n",subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
1.126     brouard  6957:    fprintf(fichtm,"\
                   6958:  - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
1.201     brouard  6959:           stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
1.126     brouard  6960:    fprintf(fichtm,"\
1.217     brouard  6961:  - Estimated back transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
                   6962:           stepm,subdirf2(fileresu,"PIJB_"),subdirf2(fileresu,"PIJB_"));
                   6963:    fprintf(fichtm,"\
1.288     brouard  6964:  - Period (forward) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6965:           subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
1.126     brouard  6966:    fprintf(fichtm,"\
1.288     brouard  6967:  - Backward prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
1.217     brouard  6968:           subdirf2(fileresu,"PLB_"),subdirf2(fileresu,"PLB_"));
                   6969:    fprintf(fichtm,"\
1.211     brouard  6970:  - (a) Life expectancies by health status at initial age, e<sub>i.</sub> (b) health expectancies by health status at initial age, e<sub>ij</sub> . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
1.126     brouard  6971:    <a href=\"%s\">%s</a> <br>\n",
1.201     brouard  6972:           estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
1.211     brouard  6973:    if(prevfcast==1){
                   6974:      fprintf(fichtm,"\
                   6975:  - Prevalence projections by age and states:                           \
1.201     brouard  6976:    <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
1.211     brouard  6977:    }
1.126     brouard  6978: 
                   6979: 
1.225     brouard  6980:    m=pow(2,cptcoveff);
1.222     brouard  6981:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  6982: 
1.264     brouard  6983:    fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
                   6984: 
                   6985:    jj1=0;
                   6986: 
                   6987:    fprintf(fichtm," \n<ul>");
                   6988:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   6989:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
                   6990:      if(m != 1 && TKresult[nres]!= k1)
                   6991:        continue;
                   6992:      jj1++;
                   6993:      if (cptcovn > 0) {
                   6994:        fprintf(fichtm,"\n<li><a  size=\"1\" color=\"#EC5E5E\" href=\"#rescov");
                   6995:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   6996:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   6997:        }
                   6998:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   6999:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7000:        }
                   7001:        fprintf(fichtm,"\">");
                   7002:        
                   7003:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
                   7004:        fprintf(fichtm,"************ Results for covariates");
                   7005:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7006:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7007:        }
                   7008:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7009:         fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7010:        }
                   7011:        if(invalidvarcomb[k1]){
                   7012:         fprintf(fichtm," Warning Combination (%d) ignored because no cases ",k1); 
                   7013:         continue;
                   7014:        }
                   7015:        fprintf(fichtm,"</a></li>");
                   7016:      } /* cptcovn >0 */
                   7017:    }
                   7018:      fprintf(fichtm," \n</ul>");
                   7019: 
1.222     brouard  7020:    jj1=0;
1.237     brouard  7021: 
                   7022:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
1.241     brouard  7023:    for(k1=1; k1<=m;k1++){ /* For each combination of covariate */
1.253     brouard  7024:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7025:        continue;
1.220     brouard  7026: 
1.222     brouard  7027:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7028:      jj1++;
                   7029:      if (cptcovn > 0) {
1.264     brouard  7030:        fprintf(fichtm,"\n<p><a name=\"rescov");
                   7031:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
                   7032:         fprintf(fichtm,"_V%d=%d_",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7033:        }
                   7034:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7035:         fprintf(fichtm,"_V%d=%f_",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7036:        }
                   7037:        fprintf(fichtm,"\"</a>");
                   7038:  
1.222     brouard  7039:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7040:        for (cpt=1; cpt<=cptcoveff;cpt++){ 
1.237     brouard  7041:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],(int)Tresult[nres][cpt]);
                   7042:         printf(" V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);fflush(stdout);
                   7043:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7044:         /* printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout); */
1.222     brouard  7045:        }
1.237     brouard  7046:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7047:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7048:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);fflush(stdout);
                   7049:       }
                   7050:        
1.230     brouard  7051:        /* if(nqfveff+nqtveff 0) */ /* Test to be done */
1.222     brouard  7052:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
                   7053:        if(invalidvarcomb[k1]){
                   7054:         fprintf(fichtm,"\n<h3>Combination (%d) ignored because no cases </h3>\n",k1); 
                   7055:         printf("\nCombination (%d) ignored because no cases \n",k1); 
                   7056:         continue;
                   7057:        }
                   7058:      }
                   7059:      /* aij, bij */
1.259     brouard  7060:      fprintf(fichtm,"<br>- Logit model (yours is: logit(pij)=log(pij/pii)= aij+ bij age+%s) as a function of age: <a href=\"%s_%d-1-%d.svg\">%s_%d-1-%d.svg</a><br> \
1.241     brouard  7061: <img src=\"%s_%d-1-%d.svg\">",model,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);
1.222     brouard  7062:      /* Pij */
1.241     brouard  7063:      fprintf(fichtm,"<br>\n- P<sub>ij</sub> or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2-%d.svg\">%s_%d-2-%d.svg</a><br> \
                   7064: <img src=\"%s_%d-2-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres);     
1.222     brouard  7065:      /* Quasi-incidences */
                   7066:      fprintf(fichtm,"<br>\n- I<sub>ij</sub> or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
1.220     brouard  7067:  before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too, \
1.211     brouard  7068:  incidence (rates) are the limit when h tends to zero of the ratio of the probability  <sub>h</sub>P<sub>ij</sub> \
1.241     brouard  7069: divided by h: <sub>h</sub>P<sub>ij</sub>/h : <a href=\"%s_%d-3-%d.svg\">%s_%d-3-%d.svg</a><br> \
                   7070: <img src=\"%s_%d-3-%d.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres,subdirf2(optionfilefiname,"PE_"),k1,nres); 
1.222     brouard  7071:      /* Survival functions (period) in state j */
                   7072:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7073:        fprintf(fichtm,"<br>\n- Survival functions in state %d. And probability to be observed in state %d being in state (1 to %d) at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7074: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.222     brouard  7075:      }
                   7076:      /* State specific survival functions (period) */
                   7077:      for(cpt=1; cpt<=nlstate;cpt++){
1.292     brouard  7078:        fprintf(fichtm,"<br>\n- Survival functions in state %d and in any other live state (total).\
                   7079:  And probability to be observed in various states (up to %d) being in state %d at different ages.      \
1.283     brouard  7080:  <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres,subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.222     brouard  7081:      }
1.288     brouard  7082:      /* Period (forward stable) prevalence in each health state */
1.222     brouard  7083:      for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7084:        fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability for a person being in state (1 to %d) at different ages, to be in state %d some years after. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
                   7085: <img src=\"%s_%d-%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres,subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.222     brouard  7086:      }
1.296     brouard  7087:      if(prevbcast==1){
1.288     brouard  7088:        /* Backward prevalence in each health state */
1.222     brouard  7089:        for(cpt=1; cpt<=nlstate;cpt++){
1.264     brouard  7090:         fprintf(fichtm,"<br>\n- Convergence to mixed (stable) back prevalence in state %d. Or probability for a person to be in state %d at a younger age, knowing that she/he was in state (1 to %d) at different older ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a><br> \
1.241     brouard  7091: <img src=\"%s_%d-%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.222     brouard  7092:        }
1.217     brouard  7093:      }
1.222     brouard  7094:      if(prevfcast==1){
1.288     brouard  7095:        /* Projection of prevalence up to period (forward stable) prevalence in each health state */
1.222     brouard  7096:        for(cpt=1; cpt<=nlstate;cpt++){
1.314     brouard  7097:         fprintf(fichtm,"<br>\n- Projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), from year %.1f up to year %.1f tending to period (stable) forward prevalence in state %d. Or probability to be in state %d being in an observed weighted state (from 1 to %d). <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>", dateprev1, dateprev2, mobilavproj, dateprojd, dateprojf, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
                   7098:         fprintf(fichtm," (data from text file  <a href=\"%s.txt\">%s.txt</a>)\n<br>",subdirf2(optionfilefiname,"F_"),subdirf2(optionfilefiname,"F_"));
                   7099:         fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">",
                   7100:                 subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.222     brouard  7101:        }
                   7102:      }
1.296     brouard  7103:      if(prevbcast==1){
1.268     brouard  7104:       /* Back projection of prevalence up to stable (mixed) back-prevalence in each health state */
                   7105:        for(cpt=1; cpt<=nlstate;cpt++){
1.273     brouard  7106:         fprintf(fichtm,"<br>\n- Back projection of cross-sectional prevalence (estimated with cases observed from %.1f to %.1f and mobil_average=%d), \
                   7107:  from year %.1f up to year %.1f (probably close to stable [mixed] back prevalence in state %d (randomness in cross-sectional prevalence is not taken into \
                   7108:  account but can visually be appreciated). Or probability to have been in an state %d, knowing that the person was in either state (1 or %d) \
1.314     brouard  7109: with weights corresponding to observed prevalence at different ages. <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>", dateprev1, dateprev2, mobilavproj, dateback1, dateback2, cpt, cpt, nlstate, subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres,subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7110:         fprintf(fichtm," (data from text file  <a href=\"%s.txt\">%s.txt</a>)\n<br>",subdirf2(optionfilefiname,"FB_"),subdirf2(optionfilefiname,"FB_"));
                   7111:         fprintf(fichtm," <img src=\"%s_%d-%d-%d.svg\">", subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
1.268     brouard  7112:        }
                   7113:      }
1.220     brouard  7114:         
1.222     brouard  7115:      for(cpt=1; cpt<=nlstate;cpt++) {
1.314     brouard  7116:        fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d-%d-%d.svg\">%s_%d-%d-%d.svg</a>",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres,subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
                   7117:        fprintf(fichtm," (data from text file  <a href=\"%s.txt\"> %s.txt</a>)\n<br>",subdirf2(optionfilefiname,"E_"),subdirf2(optionfilefiname,"E_"));
                   7118:        fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">", subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres );
1.222     brouard  7119:      }
                   7120:      /* } /\* end i1 *\/ */
                   7121:    }/* End k1 */
                   7122:    fprintf(fichtm,"</ul>");
1.126     brouard  7123: 
1.222     brouard  7124:    fprintf(fichtm,"\
1.126     brouard  7125: \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
1.193     brouard  7126:  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
1.203     brouard  7127:  - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
1.197     brouard  7128: But because parameters are usually highly correlated (a higher incidence of disability \
                   7129: and a higher incidence of recovery can give very close observed transition) it might \
                   7130: be very useful to look not only at linear confidence intervals estimated from the \
                   7131: variances but at the covariance matrix. And instead of looking at the estimated coefficients \
                   7132: (parameters) of the logistic regression, it might be more meaningful to visualize the \
                   7133: covariance matrix of the one-step probabilities. \
                   7134: See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
1.126     brouard  7135: 
1.222     brouard  7136:    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
                   7137:           subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
                   7138:    fprintf(fichtm,"\
1.126     brouard  7139:  - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7140:           subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
1.126     brouard  7141: 
1.222     brouard  7142:    fprintf(fichtm,"\
1.126     brouard  7143:  - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7144:           subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
                   7145:    fprintf(fichtm,"\
1.126     brouard  7146:  - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
                   7147:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7148:           estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
1.222     brouard  7149:    fprintf(fichtm,"\
1.126     brouard  7150:  - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
                   7151:    <a href=\"%s\">%s</a> <br>\n</li>",
1.201     brouard  7152:           estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
1.222     brouard  7153:    fprintf(fichtm,"\
1.288     brouard  7154:  - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the forward (period) prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
1.222     brouard  7155:           estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
                   7156:    fprintf(fichtm,"\
1.128     brouard  7157:  - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
1.222     brouard  7158:           estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
                   7159:    fprintf(fichtm,"\
1.288     brouard  7160:  - Standard deviation of forward (period) prevalences: <a href=\"%s\">%s</a> <br>\n",\
1.222     brouard  7161:           subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
1.126     brouard  7162: 
                   7163: /*  if(popforecast==1) fprintf(fichtm,"\n */
                   7164: /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
                   7165: /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
                   7166: /*     <br>",fileres,fileres,fileres,fileres); */
                   7167: /*  else  */
                   7168: /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
1.222     brouard  7169:    fflush(fichtm);
                   7170:    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
1.126     brouard  7171: 
1.225     brouard  7172:    m=pow(2,cptcoveff);
1.222     brouard  7173:    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
1.126     brouard  7174: 
1.222     brouard  7175:    jj1=0;
1.237     brouard  7176: 
1.241     brouard  7177:    for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.222     brouard  7178:    for(k1=1; k1<=m;k1++){
1.253     brouard  7179:      if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7180:        continue;
1.222     brouard  7181:      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
                   7182:      jj1++;
1.126     brouard  7183:      if (cptcovn > 0) {
                   7184:        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
1.225     brouard  7185:        for (cpt=1; cpt<=cptcoveff;cpt++)  /**< cptcoveff number of variables */
1.237     brouard  7186:         fprintf(fichtm," V%d=%d ",Tvresult[nres][cpt],Tresult[nres][cpt]);
                   7187:         /* fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]); */
                   7188:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7189:        fprintf(fichtm," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7190:       }
                   7191: 
1.126     brouard  7192:        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
1.220     brouard  7193: 
1.222     brouard  7194:        if(invalidvarcomb[k1]){
                   7195:         fprintf(fichtm,"\n<h4>Combination (%d) ignored because no cases </h4>\n",k1); 
                   7196:         continue;
                   7197:        }
1.126     brouard  7198:      }
                   7199:      for(cpt=1; cpt<=nlstate;cpt++) {
1.258     brouard  7200:        fprintf(fichtm,"\n<br>- Observed (cross-sectional with mov_average=%d) and period (incidence based) \
1.314     brouard  7201: prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d-%d-%d.svg\"> %s_%d-%d-%d.svg</a>",mobilav,cpt,subdirf2(optionfilefiname,"V_"),cpt,k1,nres,subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7202:        fprintf(fichtm," (data from text file  <a href=\"%s\">%s</a>)\n <br>",subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
                   7203:        fprintf(fichtm,"<img src=\"%s_%d-%d-%d.svg\">",subdirf2(optionfilefiname,"V_"), cpt,k1,nres);
1.126     brouard  7204:      }
                   7205:      fprintf(fichtm,"\n<br>- Total life expectancy by age and \
1.314     brouard  7206: health expectancies in each live states (1 to %d). If popbased=1 the smooth (due to the model) \
1.128     brouard  7207: true period expectancies (those weighted with period prevalences are also\
                   7208:  drawn in addition to the population based expectancies computed using\
1.314     brouard  7209:  observed and cahotic prevalences:  <a href=\"%s_%d-%d.svg\">%s_%d-%d.svg</a>",nlstate, subdirf2(optionfilefiname,"E_"),k1,nres,subdirf2(optionfilefiname,"E_"),k1,nres);
                   7210:      fprintf(fichtm," (data from text file <a href=\"%s.txt\">%s.txt</a>) \n<br>",subdirf2(optionfilefiname,"T_"),subdirf2(optionfilefiname,"T_"));
                   7211:      fprintf(fichtm,"<img src=\"%s_%d-%d.svg\">",subdirf2(optionfilefiname,"E_"),k1,nres);
1.222     brouard  7212:      /* } /\* end i1 *\/ */
                   7213:    }/* End k1 */
1.241     brouard  7214:   }/* End nres */
1.222     brouard  7215:    fprintf(fichtm,"</ul>");
                   7216:    fflush(fichtm);
1.126     brouard  7217: }
                   7218: 
                   7219: /******************* Gnuplot file **************/
1.296     brouard  7220: void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double bage, double fage , int prevfcast, int prevbcast, char pathc[], double p[], int offyear, int offbyear){
1.126     brouard  7221: 
                   7222:   char dirfileres[132],optfileres[132];
1.264     brouard  7223:   char gplotcondition[132], gplotlabel[132];
1.237     brouard  7224:   int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,k4=0,ij=0, ijp=0, l=0;
1.211     brouard  7225:   int lv=0, vlv=0, kl=0;
1.130     brouard  7226:   int ng=0;
1.201     brouard  7227:   int vpopbased;
1.223     brouard  7228:   int ioffset; /* variable offset for columns */
1.270     brouard  7229:   int iyearc=1; /* variable column for year of projection  */
                   7230:   int iagec=1; /* variable column for age of projection  */
1.235     brouard  7231:   int nres=0; /* Index of resultline */
1.266     brouard  7232:   int istart=1; /* For starting graphs in projections */
1.219     brouard  7233: 
1.126     brouard  7234: /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
                   7235: /*     printf("Problem with file %s",optionfilegnuplot); */
                   7236: /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
                   7237: /*   } */
                   7238: 
                   7239:   /*#ifdef windows */
                   7240:   fprintf(ficgp,"cd \"%s\" \n",pathc);
1.223     brouard  7241:   /*#endif */
1.225     brouard  7242:   m=pow(2,cptcoveff);
1.126     brouard  7243: 
1.274     brouard  7244:   /* diagram of the model */
                   7245:   fprintf(ficgp,"\n#Diagram of the model \n");
                   7246:   fprintf(ficgp,"\ndelta=0.03;delta2=0.07;unset arrow;\n");
                   7247:   fprintf(ficgp,"yoff=(%d > 2? 0:1);\n",nlstate);
                   7248:   fprintf(ficgp,"\n#Peripheral arrows\nset for [i=1:%d] for [j=1:%d] arrow i*10+j from cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.95*(cos(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0) - cos(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta2:0)), -0.95*(sin(pi*((1-(%d/2)*2./%d)/2+(i-1)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) - sin(pi*((1-(%d/2)*2./%d)/2+(j-1)*2./%d))+( i!=j?(i-j)/abs(i-j)*delta2:0)) ls (i < j? 1:2)\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7249: 
                   7250:   fprintf(ficgp,"\n#Centripete arrows (turning in other direction (1-i) instead of (i-1)) \nset for [i=1:%d] arrow (%d+1)*10+i from cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))-(i!=j?(i-j)/abs(i-j)*delta:0), yoff +sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) rto -0.80*(cos(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d))+(i!=j?(i-j)/abs(i-j)*delta:0)  ), -0.80*(sin(pi*((1-(%d/2)*2./%d)/2+(1-i)*2./%d)) + (i!=j?(i-j)/abs(i-j)*delta:0) + yoff ) ls 4\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7251:   fprintf(ficgp,"\n#show arrow\nunset label\n");
                   7252:   fprintf(ficgp,"\n#States labels, starting from 2 (2-i) instead of (1-i), was (i-1)\nset for [i=1:%d] label i sprintf(\"State %%d\",i) center at cos(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)), yoff+sin(pi*((1-(%d/2)*2./%d)/2+(2-i)*2./%d)) font \"helvetica, 16\" tc rgbcolor \"blue\"\n",nlstate,nlstate,nlstate,nlstate,nlstate,nlstate,nlstate);
                   7253:   fprintf(ficgp,"\nset label %d+1 sprintf(\"State %%d\",%d+1) center at 0.,0.  font \"helvetica, 16\" tc rgbcolor \"red\"\n",nlstate,nlstate);
                   7254:   fprintf(ficgp,"\n#show label\nunset border;unset xtics; unset ytics;\n");
                   7255:   fprintf(ficgp,"\n\nset ter svg size 640, 480;set out \"%s_.svg\" \n",subdirf2(optionfilefiname,"D_"));
                   7256:   fprintf(ficgp,"unset log y; plot [-1.2:1.2][yoff-1.2:1.2] 1/0 not; set out;reset;\n");
                   7257: 
1.202     brouard  7258:   /* Contribution to likelihood */
                   7259:   /* Plot the probability implied in the likelihood */
1.223     brouard  7260:   fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
                   7261:   fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
                   7262:   /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
                   7263:   fprintf(ficgp,"\nset ter pngcairo size 640, 480");
1.204     brouard  7264: /* nice for mle=4 plot by number of matrix products.
1.202     brouard  7265:    replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
                   7266: /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
1.223     brouard  7267:   /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
                   7268:   fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7269:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):6 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
                   7270:   fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
                   7271:   fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$13):5 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
                   7272:   for (i=1; i<= nlstate ; i ++) {
                   7273:     fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
                   7274:     fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
                   7275:     fprintf(ficgp,"  u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
                   7276:     for (j=2; j<= nlstate+ndeath ; j ++) {
                   7277:       fprintf(ficgp,",\\\n \"\" u  2:($5 == %d && $6==%d ? $10 : 1/0):($12/4.):6 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
                   7278:     }
                   7279:     fprintf(ficgp,";\nset out; unset ylabel;\n"); 
                   7280:   }
                   7281:   /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */               
                   7282:   /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
                   7283:   /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
                   7284:   fprintf(ficgp,"\nset out;unset log\n");
                   7285:   /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
1.202     brouard  7286: 
1.126     brouard  7287:   strcpy(dirfileres,optionfilefiname);
                   7288:   strcpy(optfileres,"vpl");
1.223     brouard  7289:   /* 1eme*/
1.238     brouard  7290:   for (cpt=1; cpt<= nlstate ; cpt ++){ /* For each live state */
                   7291:     for (k1=1; k1<= m ; k1 ++){ /* For each valid combination of covariate */
1.236     brouard  7292:       for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.238     brouard  7293:        /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
1.253     brouard  7294:        if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7295:          continue;
                   7296:        /* We are interested in selected combination by the resultline */
1.246     brouard  7297:        /* printf("\n# 1st: Period (stable) prevalence with CI: 'VPL_' files and live state =%d ", cpt); */
1.288     brouard  7298:        fprintf(ficgp,"\n# 1st: Forward (stable period) prevalence with CI: 'VPL_' files  and live state =%d ", cpt);
1.264     brouard  7299:        strcpy(gplotlabel,"(");
1.238     brouard  7300:        for (k=1; k<=cptcoveff; k++){    /* For each covariate k get corresponding value lv for combination k1 */
                   7301:          lv= decodtabm(k1,k,cptcoveff); /* Should be the value of the covariate corresponding to k1 combination */
                   7302:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7303:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7304:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7305:          vlv= nbcode[Tvaraff[k]][lv]; /* vlv is the value of the covariate lv, 0 or 1 */
                   7306:          /* For each combination of covariate k1 (V1=1, V3=0), we printed the current covariate k and its value vlv */
1.246     brouard  7307:          /* printf(" V%d=%d ",Tvaraff[k],vlv); */
1.238     brouard  7308:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7309:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7310:        }
                   7311:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.246     brouard  7312:          /* printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]); */
1.238     brouard  7313:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7314:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7315:        }
                   7316:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.246     brouard  7317:        /* printf("\n#\n"); */
1.238     brouard  7318:        fprintf(ficgp,"\n#\n");
                   7319:        if(invalidvarcomb[k1]){
1.260     brouard  7320:           /*k1=k1-1;*/ /* To be checked */
1.238     brouard  7321:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7322:          continue;
                   7323:        }
1.235     brouard  7324:       
1.241     brouard  7325:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1,nres);
                   7326:        fprintf(ficgp,"\n#set out \"V_%s_%d-%d-%d.svg\" \n",optionfilefiname,cpt,k1,nres);
1.276     brouard  7327:        /* fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel); */
                   7328:        fprintf(ficgp,"set title \"Alive state %d %s\" font \"Helvetica,12\"\n",cpt,gplotlabel);
1.260     brouard  7329:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
                   7330:        /* fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter svg size 640, 480\nplot [%.f:%.f] \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1,nres); */
                   7331:       /* k1-1 error should be nres-1*/
1.238     brouard  7332:        for (i=1; i<= nlstate ; i ++) {
                   7333:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7334:          else        fprintf(ficgp," %%*lf (%%*lf)");
                   7335:        }
1.288     brouard  7336:        fprintf(ficgp,"\" t\"Forward prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres);
1.238     brouard  7337:        for (i=1; i<= nlstate ; i ++) {
                   7338:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7339:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7340:        } 
1.260     brouard  7341:        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VPL_"),nres-1,nres-1,nres); 
1.238     brouard  7342:        for (i=1; i<= nlstate ; i ++) {
                   7343:          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7344:          else fprintf(ficgp," %%*lf (%%*lf)");
                   7345:        }  
1.265     brouard  7346:        /* fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence\" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1)); */
                   7347:        
                   7348:        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" u 1:((",subdirf2(fileresu,"P_"));
                   7349:         if(cptcoveff ==0){
1.271     brouard  7350:          fprintf(ficgp,"$%d)) t 'Observed prevalence in state %d' with line lt 3",      2+3*(cpt-1),  cpt );
1.265     brouard  7351:        }else{
                   7352:          kl=0;
                   7353:          for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7354:            lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7355:            /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7356:            /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7357:            /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7358:            vlv= nbcode[Tvaraff[k]][lv];
                   7359:            kl++;
                   7360:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7361:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7362:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7363:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7364:            if(k==cptcoveff){
                   7365:              fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Observed prevalence in state %d' w l lt 2",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
                   7366:                      2+cptcoveff*2+3*(cpt-1),  cpt );  /* 4 or 6 ?*/
                   7367:            }else{
                   7368:              fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7369:              kl++;
                   7370:            }
                   7371:          } /* end covariate */
                   7372:        } /* end if no covariate */
                   7373: 
1.296     brouard  7374:        if(prevbcast==1){ /* We need to get the corresponding values of the covariates involved in this combination k1 */
1.238     brouard  7375:          /* fprintf(ficgp,",\"%s\" every :::%d::%d u 1:($%d) t\"Backward stable prevalence\" w l lt 3",subdirf2(fileresu,"PLB_"),k1-1,k1-1,1+cpt); */
1.242     brouard  7376:          fprintf(ficgp,",\"%s\" u 1:((",subdirf2(fileresu,"PLB_")); /* Age is in 1, nres in 2 to be fixed */
1.238     brouard  7377:          if(cptcoveff ==0){
1.245     brouard  7378:            fprintf(ficgp,"$%d)) t 'Backward prevalence in state %d' with line lt 3",    2+(cpt-1),  cpt );
1.238     brouard  7379:          }else{
                   7380:            kl=0;
                   7381:            for (k=1; k<=cptcoveff; k++){    /* For each combination of covariate  */
                   7382:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7383:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7384:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7385:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7386:              vlv= nbcode[Tvaraff[k]][lv];
1.223     brouard  7387:              kl++;
1.238     brouard  7388:              /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7389:              /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7390:              /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7391:              /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7392:              if(k==cptcoveff){
1.245     brouard  7393:                fprintf(ficgp,"$%d==%d && $%d==%d)? $%d : 1/0) t 'Backward prevalence in state %d' w l lt 3",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv], \
1.242     brouard  7394:                        2+cptcoveff*2+(cpt-1),  cpt );  /* 4 or 6 ?*/
1.238     brouard  7395:              }else{
                   7396:                fprintf(ficgp,"$%d==%d && $%d==%d && ",kl+1, Tvaraff[k],kl+1+1,nbcode[Tvaraff[k]][lv]);
                   7397:                kl++;
                   7398:              }
                   7399:            } /* end covariate */
                   7400:          } /* end if no covariate */
1.296     brouard  7401:          if(prevbcast == 1){
1.268     brouard  7402:            fprintf(ficgp,", \"%s\" every :::%d::%d u 1:($2==%d ? $3:1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
                   7403:            /* k1-1 error should be nres-1*/
                   7404:            for (i=1; i<= nlstate ; i ++) {
                   7405:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7406:              else        fprintf(ficgp," %%*lf (%%*lf)");
                   7407:            }
1.271     brouard  7408:            fprintf(ficgp,"\" t\"Backward (stable) prevalence\" w l lt 6 dt 3,\"%s\" every :::%d::%d u 1:($2==%d ? $3+1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres);
1.268     brouard  7409:            for (i=1; i<= nlstate ; i ++) {
                   7410:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7411:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7412:            } 
1.276     brouard  7413:            fprintf(ficgp,"\" t\"95%% CI\" w l lt 4,\"%s\" every :::%d::%d u 1:($2==%d ? $3-1.96*$4 : 1/0) \"%%lf %%lf",subdirf2(fileresu,"VBL_"),nres-1,nres-1,nres); 
1.268     brouard  7414:            for (i=1; i<= nlstate ; i ++) {
                   7415:              if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
                   7416:              else fprintf(ficgp," %%*lf (%%*lf)");
                   7417:            } 
1.274     brouard  7418:            fprintf(ficgp,"\" t\"\" w l lt 4");
1.268     brouard  7419:          } /* end if backprojcast */
1.296     brouard  7420:        } /* end if prevbcast */
1.276     brouard  7421:        /* fprintf(ficgp,"\nset out ;unset label;\n"); */
                   7422:        fprintf(ficgp,"\nset out ;unset title;\n");
1.238     brouard  7423:       } /* nres */
1.201     brouard  7424:     } /* k1 */
                   7425:   } /* cpt */
1.235     brouard  7426: 
                   7427:   
1.126     brouard  7428:   /*2 eme*/
1.238     brouard  7429:   for (k1=1; k1<= m ; k1 ++){  
                   7430:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7431:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7432:        continue;
                   7433:       fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files ");
1.264     brouard  7434:       strcpy(gplotlabel,"(");
1.238     brouard  7435:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.225     brouard  7436:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
1.223     brouard  7437:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7438:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7439:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7440:        vlv= nbcode[Tvaraff[k]][lv];
                   7441:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7442:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7443:       }
1.237     brouard  7444:       /* for(k=1; k <= ncovds; k++){ */
1.236     brouard  7445:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  7446:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.236     brouard  7447:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7448:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7449:       }
1.264     brouard  7450:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7451:       fprintf(ficgp,"\n#\n");
1.223     brouard  7452:       if(invalidvarcomb[k1]){
                   7453:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7454:        continue;
                   7455:       }
1.219     brouard  7456:                        
1.241     brouard  7457:       fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1,nres);
1.238     brouard  7458:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.264     brouard  7459:        fprintf(ficgp,"\nset label \"popbased %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",vpopbased,gplotlabel);
                   7460:        if(vpopbased==0){
1.238     brouard  7461:          fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
1.264     brouard  7462:        }else
1.238     brouard  7463:          fprintf(ficgp,"\nreplot ");
                   7464:        for (i=1; i<= nlstate+1 ; i ++) {
                   7465:          k=2*i;
1.261     brouard  7466:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1, vpopbased);
1.238     brouard  7467:          for (j=1; j<= nlstate+1 ; j ++) {
                   7468:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7469:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7470:          }   
                   7471:          if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
                   7472:          else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
1.261     brouard  7473:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7474:          for (j=1; j<= nlstate+1 ; j ++) {
                   7475:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7476:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7477:          }   
                   7478:          fprintf(ficgp,"\" t\"\" w l lt 0,");
1.261     brouard  7479:          fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),nres-1,nres-1,vpopbased);
1.238     brouard  7480:          for (j=1; j<= nlstate+1 ; j ++) {
                   7481:            if (j==i) fprintf(ficgp," %%lf (%%lf)");
                   7482:            else fprintf(ficgp," %%*lf (%%*lf)");
                   7483:          }   
                   7484:          if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
                   7485:          else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
                   7486:        } /* state */
                   7487:       } /* vpopbased */
1.264     brouard  7488:       fprintf(ficgp,"\nset out;set out \"%s_%d-%d.svg\"; replot; set out; unset label;\n",subdirf2(optionfilefiname,"E_"),k1,nres); /* Buggy gnuplot */
1.238     brouard  7489:     } /* end nres */
                   7490:   } /* k1 end 2 eme*/
                   7491:        
                   7492:        
                   7493:   /*3eme*/
                   7494:   for (k1=1; k1<= m ; k1 ++){
                   7495:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7496:       if(m != 1 && TKresult[nres]!= k1)
1.238     brouard  7497:        continue;
                   7498: 
                   7499:       for (cpt=1; cpt<= nlstate ; cpt ++) {
1.261     brouard  7500:        fprintf(ficgp,"\n\n# 3d: Life expectancy with EXP_ files:  combination=%d state=%d",k1, cpt);
1.264     brouard  7501:        strcpy(gplotlabel,"(");
1.238     brouard  7502:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7503:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7504:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7505:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7506:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7507:          vlv= nbcode[Tvaraff[k]][lv];
                   7508:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7509:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7510:        }
                   7511:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7512:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7513:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7514:        }       
1.264     brouard  7515:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7516:        fprintf(ficgp,"\n#\n");
                   7517:        if(invalidvarcomb[k1]){
                   7518:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7519:          continue;
                   7520:        }
                   7521:                        
                   7522:        /*       k=2+nlstate*(2*cpt-2); */
                   7523:        k=2+(nlstate+1)*(cpt-1);
1.241     brouard  7524:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1,nres);
1.264     brouard  7525:        fprintf(ficgp,"set label \"%s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel);
1.238     brouard  7526:        fprintf(ficgp,"set ter svg size 640, 480\n\
1.261     brouard  7527: plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),nres-1,nres-1,k,cpt);
1.238     brouard  7528:        /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7529:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7530:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
                   7531:          fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
                   7532:          for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
                   7533:          fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
1.219     brouard  7534:                                
1.238     brouard  7535:        */
                   7536:        for (i=1; i< nlstate ; i ++) {
1.261     brouard  7537:          fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+i,cpt,i+1);
1.238     brouard  7538:          /*    fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
1.219     brouard  7539:                                
1.238     brouard  7540:        } 
1.261     brouard  7541:        fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),nres-1,nres-1,k+nlstate,cpt);
1.238     brouard  7542:       }
1.264     brouard  7543:       fprintf(ficgp,"\nunset label;\n");
1.238     brouard  7544:     } /* end nres */
                   7545:   } /* end kl 3eme */
1.126     brouard  7546:   
1.223     brouard  7547:   /* 4eme */
1.201     brouard  7548:   /* Survival functions (period) from state i in state j by initial state i */
1.238     brouard  7549:   for (k1=1; k1<=m; k1++){    /* For each covariate and each value */
                   7550:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7551:       if(m != 1 && TKresult[nres]!= k1)
1.223     brouard  7552:        continue;
1.238     brouard  7553:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state cpt*/
1.264     brouard  7554:        strcpy(gplotlabel,"(");
1.238     brouard  7555:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'LIJ_' files, cov=%d state=%d",k1, cpt);
                   7556:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7557:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7558:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7559:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7560:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7561:          vlv= nbcode[Tvaraff[k]][lv];
                   7562:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7563:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7564:        }
                   7565:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7566:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7567:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7568:        }       
1.264     brouard  7569:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7570:        fprintf(ficgp,"\n#\n");
                   7571:        if(invalidvarcomb[k1]){
                   7572:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7573:          continue;
1.223     brouard  7574:        }
1.238     brouard  7575:       
1.241     brouard  7576:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1,nres);
1.264     brouard  7577:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7578:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7579: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7580:        k=3;
                   7581:        for (i=1; i<= nlstate ; i ++){
                   7582:          if(i==1){
                   7583:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7584:          }else{
                   7585:            fprintf(ficgp,", '' ");
                   7586:          }
                   7587:          l=(nlstate+ndeath)*(i-1)+1;
                   7588:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7589:          for (j=2; j<= nlstate+ndeath ; j ++)
                   7590:            fprintf(ficgp,"+$%d",k+l+j-1);
                   7591:          fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
                   7592:        } /* nlstate */
1.264     brouard  7593:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7594:       } /* end cpt state*/ 
                   7595:     } /* end nres */
                   7596:   } /* end covariate k1 */  
                   7597: 
1.220     brouard  7598: /* 5eme */
1.201     brouard  7599:   /* Survival functions (period) from state i in state j by final state j */
1.238     brouard  7600:   for (k1=1; k1<= m ; k1++){ /* For each covariate combination if any */
                   7601:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7602:       if(m != 1 && TKresult[nres]!= k1)
1.227     brouard  7603:        continue;
1.238     brouard  7604:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
1.264     brouard  7605:        strcpy(gplotlabel,"(");
1.238     brouard  7606:        fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
                   7607:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7608:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7609:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7610:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7611:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7612:          vlv= nbcode[Tvaraff[k]][lv];
                   7613:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7614:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.238     brouard  7615:        }
                   7616:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7617:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7618:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.238     brouard  7619:        }       
1.264     brouard  7620:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.238     brouard  7621:        fprintf(ficgp,"\n#\n");
                   7622:        if(invalidvarcomb[k1]){
                   7623:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7624:          continue;
                   7625:        }
1.227     brouard  7626:       
1.241     brouard  7627:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1,nres);
1.264     brouard  7628:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.238     brouard  7629:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
                   7630: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7631:        k=3;
                   7632:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7633:          if(j==1)
                   7634:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7635:          else
                   7636:            fprintf(ficgp,", '' ");
                   7637:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7638:          fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
                   7639:          /* for (i=2; i<= nlstate+ndeath ; i ++) */
                   7640:          /*   fprintf(ficgp,"+$%d",k+l+i-1); */
                   7641:          fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
                   7642:        } /* nlstate */
                   7643:        fprintf(ficgp,", '' ");
                   7644:        fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
                   7645:        for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
                   7646:          l=(nlstate+ndeath)*(cpt-1) +j;
                   7647:          if(j < nlstate)
                   7648:            fprintf(ficgp,"$%d +",k+l);
                   7649:          else
                   7650:            fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
                   7651:        }
1.264     brouard  7652:        fprintf(ficgp,"\nset out; unset label;\n");
1.238     brouard  7653:       } /* end cpt state*/ 
                   7654:     } /* end covariate */  
                   7655:   } /* end nres */
1.227     brouard  7656:   
1.220     brouard  7657: /* 6eme */
1.202     brouard  7658:   /* CV preval stable (period) for each covariate */
1.237     brouard  7659:   for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7660:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7661:     if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7662:       continue;
1.255     brouard  7663:     for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state of arrival */
1.264     brouard  7664:       strcpy(gplotlabel,"(");      
1.288     brouard  7665:       fprintf(ficgp,"\n#\n#\n#CV preval stable (forward): 'pij' files, covariatecombination#=%d state=%d",k1, cpt);
1.225     brouard  7666:       for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
1.227     brouard  7667:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7668:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7669:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7670:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7671:        vlv= nbcode[Tvaraff[k]][lv];
                   7672:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7673:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.211     brouard  7674:       }
1.237     brouard  7675:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7676:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7677:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7678:       }        
1.264     brouard  7679:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.211     brouard  7680:       fprintf(ficgp,"\n#\n");
1.223     brouard  7681:       if(invalidvarcomb[k1]){
1.227     brouard  7682:        fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7683:        continue;
1.223     brouard  7684:       }
1.227     brouard  7685:       
1.241     brouard  7686:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1,nres);
1.264     brouard  7687:       fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.126     brouard  7688:       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7689: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.211     brouard  7690:       k=3; /* Offset */
1.255     brouard  7691:       for (i=1; i<= nlstate ; i ++){ /* State of origin */
1.227     brouard  7692:        if(i==1)
                   7693:          fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
                   7694:        else
                   7695:          fprintf(ficgp,", '' ");
1.255     brouard  7696:        l=(nlstate+ndeath)*(i-1)+1; /* 1, 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7697:        fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
                   7698:        for (j=2; j<= nlstate ; j ++)
                   7699:          fprintf(ficgp,"+$%d",k+l+j-1);
                   7700:        fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
1.153     brouard  7701:       } /* nlstate */
1.264     brouard  7702:       fprintf(ficgp,"\nset out; unset label;\n");
1.153     brouard  7703:     } /* end cpt state*/ 
                   7704:   } /* end covariate */  
1.227     brouard  7705:   
                   7706:   
1.220     brouard  7707: /* 7eme */
1.296     brouard  7708:   if(prevbcast == 1){
1.288     brouard  7709:     /* CV backward prevalence  for each covariate */
1.237     brouard  7710:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7711:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7712:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7713:        continue;
1.268     brouard  7714:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life origin state */
1.264     brouard  7715:        strcpy(gplotlabel,"(");      
1.288     brouard  7716:        fprintf(ficgp,"\n#\n#\n#CV Backward stable prevalence: 'pijb' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7717:        for (k=1; k<=cptcoveff; k++){    /* For each covariate and each value */
                   7718:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate number corresponding to k1 combination */
                   7719:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7720:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
1.223     brouard  7721:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
1.227     brouard  7722:          vlv= nbcode[Tvaraff[k]][lv];
                   7723:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7724:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7725:        }
1.237     brouard  7726:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7727:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7728:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7729:        }       
1.264     brouard  7730:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7731:        fprintf(ficgp,"\n#\n");
                   7732:        if(invalidvarcomb[k1]){
                   7733:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7734:          continue;
                   7735:        }
                   7736:        
1.241     brouard  7737:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PB_"),cpt,k1,nres);
1.268     brouard  7738:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7739:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
1.238     brouard  7740: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.227     brouard  7741:        k=3; /* Offset */
1.268     brouard  7742:        for (i=1; i<= nlstate ; i ++){ /* State of arrival */
1.227     brouard  7743:          if(i==1)
                   7744:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJB_"));
                   7745:          else
                   7746:            fprintf(ficgp,", '' ");
                   7747:          /* l=(nlstate+ndeath)*(i-1)+1; */
1.255     brouard  7748:          l=(nlstate+ndeath)*(cpt-1)+1; /* fixed for i; cpt=1 1, cpt=2 1+ nlstate+ndeath, 1+2*(nlstate+ndeath) */
1.227     brouard  7749:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l); /\* a vérifier *\/ */
                   7750:          /* fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l+(cpt-1)+i-1); /\* a vérifier *\/ */
1.255     brouard  7751:          fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d",k1,k+l+i-1); /* To be verified */
1.227     brouard  7752:          /* for (j=2; j<= nlstate ; j ++) */
                   7753:          /*    fprintf(ficgp,"+$%d",k+l+j-1); */
                   7754:          /*    /\* fprintf(ficgp,"+$%d",k+l+j-1); *\/ */
1.268     brouard  7755:          fprintf(ficgp,") t \"bprev(%d,%d)\" w l",cpt,i);
1.227     brouard  7756:        } /* nlstate */
1.264     brouard  7757:        fprintf(ficgp,"\nset out; unset label;\n");
1.218     brouard  7758:       } /* end cpt state*/ 
                   7759:     } /* end covariate */  
1.296     brouard  7760:   } /* End if prevbcast */
1.218     brouard  7761:   
1.223     brouard  7762:   /* 8eme */
1.218     brouard  7763:   if(prevfcast==1){
1.288     brouard  7764:     /* Projection from cross-sectional to forward stable (period) prevalence for each covariate */
1.218     brouard  7765:     
1.237     brouard  7766:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7767:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  7768:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  7769:        continue;
1.211     brouard  7770:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
1.264     brouard  7771:        strcpy(gplotlabel,"(");      
1.288     brouard  7772:        fprintf(ficgp,"\n#\n#\n#Projection of prevalence to forward stable prevalence (period): 'PROJ_' files, covariatecombination#=%d state=%d",k1, cpt);
1.227     brouard  7773:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7774:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7775:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7776:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7777:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7778:          vlv= nbcode[Tvaraff[k]][lv];
                   7779:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
1.264     brouard  7780:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
1.227     brouard  7781:        }
1.237     brouard  7782:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7783:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  7784:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  7785:        }       
1.264     brouard  7786:        strcpy(gplotlabel+strlen(gplotlabel),")");
1.227     brouard  7787:        fprintf(ficgp,"\n#\n");
                   7788:        if(invalidvarcomb[k1]){
                   7789:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7790:          continue;
                   7791:        }
                   7792:        
                   7793:        fprintf(ficgp,"# hpijx=probability over h years, hp.jx is weighted by observed prev\n ");
1.241     brouard  7794:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJ_"),cpt,k1,nres);
1.264     brouard  7795:        fprintf(ficgp,"set label \"Alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
1.227     brouard  7796:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
1.238     brouard  7797: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
1.266     brouard  7798: 
                   7799:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7800:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7801:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7802:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
1.227     brouard  7803:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7804:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7805:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7806:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
1.266     brouard  7807:          if(i==istart){
1.227     brouard  7808:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"F_"));
                   7809:          }else{
                   7810:            fprintf(ficgp,",\\\n '' ");
                   7811:          }
                   7812:          if(cptcoveff ==0){ /* No covariate */
                   7813:            ioffset=2; /* Age is in 2 */
                   7814:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7815:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7816:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7817:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7818:            fprintf(ficgp," u %d:(", ioffset); 
1.266     brouard  7819:            if(i==nlstate+1){
1.270     brouard  7820:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'pw.%d' with line lc variable ",        \
1.266     brouard  7821:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7822:              fprintf(ficgp,",\\\n '' ");
                   7823:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7824:              fprintf(ficgp," (($1-$2) == %d ) ? $%d/(1.-$%d) : 1/0):1 with labels center not ", \
1.266     brouard  7825:                     offyear,                           \
1.268     brouard  7826:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate );
1.266     brouard  7827:            }else
1.227     brouard  7828:              fprintf(ficgp," $%d/(1.-$%d)) t 'p%d%d' with line ",      \
                   7829:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7830:          }else{ /* more than 2 covariates */
1.270     brouard  7831:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7832:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7833:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7834:            iyearc=ioffset-1;
                   7835:            iagec=ioffset;
1.227     brouard  7836:            fprintf(ficgp," u %d:(",ioffset); 
                   7837:            kl=0;
                   7838:            strcpy(gplotcondition,"(");
                   7839:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7840:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7841:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7842:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7843:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7844:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7845:              kl++;
                   7846:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7847:              kl++;
                   7848:              if(k <cptcoveff && cptcoveff>1)
                   7849:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7850:            }
                   7851:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7852:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7853:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7854:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7855:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7856:            if(i==nlstate+1){
1.270     brouard  7857:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0):%d t 'p.%d' with line lc variable", gplotcondition, \
                   7858:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,iyearc, cpt );
1.266     brouard  7859:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7860:              fprintf(ficgp," u %d:(",iagec); 
                   7861:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d/(1.-$%d) : 1/0):%d with labels center not ", gplotcondition, \
                   7862:                      iyearc, iagec, offyear,                           \
                   7863:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate, iyearc );
1.266     brouard  7864: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
1.227     brouard  7865:            }else{
                   7866:              fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \
                   7867:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), ioffset +1+(i-1)+(nlstate+1)*nlstate,i,cpt );
                   7868:            }
                   7869:          } /* end if covariate */
                   7870:        } /* nlstate */
1.264     brouard  7871:        fprintf(ficgp,"\nset out; unset label;\n");
1.223     brouard  7872:       } /* end cpt state*/
                   7873:     } /* end covariate */
                   7874:   } /* End if prevfcast */
1.227     brouard  7875:   
1.296     brouard  7876:   if(prevbcast==1){
1.268     brouard  7877:     /* Back projection from cross-sectional to stable (mixed) for each covariate */
                   7878:     
                   7879:     for (k1=1; k1<= m ; k1 ++) /* For each covariate combination if any */
                   7880:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   7881:       if(m != 1 && TKresult[nres]!= k1)
                   7882:        continue;
                   7883:       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
                   7884:        strcpy(gplotlabel,"(");      
                   7885:        fprintf(ficgp,"\n#\n#\n#Back projection of prevalence to stable (mixed) back prevalence: 'BPROJ_' files, covariatecombination#=%d originstate=%d",k1, cpt);
                   7886:        for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   7887:          lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   7888:          /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7889:          /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7890:          /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7891:          vlv= nbcode[Tvaraff[k]][lv];
                   7892:          fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   7893:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   7894:        }
                   7895:        for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   7896:          fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7897:          sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   7898:        }       
                   7899:        strcpy(gplotlabel+strlen(gplotlabel),")");
                   7900:        fprintf(ficgp,"\n#\n");
                   7901:        if(invalidvarcomb[k1]){
                   7902:          fprintf(ficgp,"#Combination (%d) ignored because no cases \n",k1); 
                   7903:          continue;
                   7904:        }
                   7905:        
                   7906:        fprintf(ficgp,"# hbijx=backprobability over h years, hb.jx is weighted by observed prev at destination state\n ");
                   7907:        fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" \n",subdirf2(optionfilefiname,"PROJB_"),cpt,k1,nres);
                   7908:        fprintf(ficgp,"set label \"Origin alive state %d %s\" at graph 0.98,0.5 center rotate font \"Helvetica,12\"\n",cpt,gplotlabel);
                   7909:        fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Prevalence\" \n\
                   7910: set ter svg size 640, 480\nunset log y\nplot [%.f:%.f]  ", ageminpar, agemaxpar);
                   7911: 
                   7912:        /* for (i=1; i<= nlstate+1 ; i ++){  /\* nlstate +1 p11 p21 p.1 *\/ */
                   7913:        istart=nlstate+1; /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7914:        /*istart=1;*/ /* Could be one if by state, but nlstate+1 is w.i projection only */
                   7915:        for (i=istart; i<= nlstate+1 ; i ++){  /* nlstate +1 p11 p21 p.1 */
                   7916:          /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7917:          /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7918:          /*# yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7919:          /*#   1       2   3    4    5      6  7   8   9   10   11 12  13   14  15 */   
                   7920:          if(i==istart){
                   7921:            fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"FB_"));
                   7922:          }else{
                   7923:            fprintf(ficgp,",\\\n '' ");
                   7924:          }
                   7925:          if(cptcoveff ==0){ /* No covariate */
                   7926:            ioffset=2; /* Age is in 2 */
                   7927:            /*# yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7928:            /*#   1       2   3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7929:            /*# V1  = 1 yearproj age p11 p21 p31 p.1 p12 p22 p32 p.2 p13 p23 p33 p.3 p14 p24 p34 p.4*/
                   7930:            /*#  1    2        3   4   5  6    7  8   9   10  11  12  13  14  15  16  17  18 */
                   7931:            fprintf(ficgp," u %d:(", ioffset); 
                   7932:            if(i==nlstate+1){
1.270     brouard  7933:              fprintf(ficgp," $%d/(1.-$%d)):1 t 'bw%d' with line lc variable ", \
1.268     brouard  7934:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt );
                   7935:              fprintf(ficgp,",\\\n '' ");
                   7936:              fprintf(ficgp," u %d:(",ioffset); 
1.270     brouard  7937:              fprintf(ficgp," (($1-$2) == %d ) ? $%d : 1/0):1 with labels center not ", \
1.268     brouard  7938:                     offbyear,                          \
                   7939:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1) );
                   7940:            }else
                   7941:              fprintf(ficgp," $%d/(1.-$%d)) t 'b%d%d' with line ",      \
                   7942:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),  ioffset+1+(i-1)+(nlstate+1)*nlstate,cpt,i );
                   7943:          }else{ /* more than 2 covariates */
1.270     brouard  7944:            ioffset=2*cptcoveff+2; /* Age is in 4 or 6 or etc.*/
                   7945:            /*#  V1  = 1  V2 =  0 yearproj age p11 p21 p.1 p12 p22 p.2 p13 p23 p.3*/
                   7946:            /*#   1    2   3    4    5      6  7   8   9   10   11 12  13   14  15 */
                   7947:            iyearc=ioffset-1;
                   7948:            iagec=ioffset;
1.268     brouard  7949:            fprintf(ficgp," u %d:(",ioffset); 
                   7950:            kl=0;
                   7951:            strcpy(gplotcondition,"(");
                   7952:            for (k=1; k<=cptcoveff; k++){    /* For each covariate writing the chain of conditions */
                   7953:              lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to combination k1 and covariate k */
                   7954:              /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   7955:              /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   7956:              /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   7957:              vlv= nbcode[Tvaraff[k]][lv]; /* Value of the modality of Tvaraff[k] */
                   7958:              kl++;
                   7959:              sprintf(gplotcondition+strlen(gplotcondition),"$%d==%d && $%d==%d " ,kl,Tvaraff[k], kl+1, nbcode[Tvaraff[k]][lv]);
                   7960:              kl++;
                   7961:              if(k <cptcoveff && cptcoveff>1)
                   7962:                sprintf(gplotcondition+strlen(gplotcondition)," && ");
                   7963:            }
                   7964:            strcpy(gplotcondition+strlen(gplotcondition),")");
                   7965:            /* kl=6+(cpt-1)*(nlstate+1)+1+(i-1); /\* 6+(1-1)*(2+1)+1+(1-1)=7, 6+(2-1)(2+1)+1+(1-1)=10 *\/ */
                   7966:            /*6+(cpt-1)*(nlstate+1)+1+(i-1)+(nlstate+1)*nlstate; 6+(1-1)*(2+1)+1+(1-1) +(2+1)*2=13 */ 
                   7967:            /*6+1+(i-1)+(nlstate+1)*nlstate; 6+1+(1-1) +(2+1)*2=13 */ 
                   7968:            /* ''  u 6:(($1==1 && $2==0 && $3==2 && $4==0)? $9/(1.-$15) : 1/0):($5==2000? 3:2) t 'p.1' with line lc variable*/
                   7969:            if(i==nlstate+1){
1.270     brouard  7970:              fprintf(ficgp,"%s ? $%d : 1/0):%d t 'bw%d' with line lc variable", gplotcondition, \
                   7971:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1),iyearc,cpt );
1.268     brouard  7972:              fprintf(ficgp,",\\\n '' ");
1.270     brouard  7973:              fprintf(ficgp," u %d:(",iagec); 
1.268     brouard  7974:              /* fprintf(ficgp,"%s && (($5-$6) == %d ) ? $%d/(1.-$%d) : 1/0):5 with labels center not ", gplotcondition, \ */
1.270     brouard  7975:              fprintf(ficgp,"%s && (($%d-$%d) == %d ) ? $%d : 1/0):%d with labels center not ", gplotcondition, \
                   7976:                      iyearc,iagec,offbyear,                            \
                   7977:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), iyearc );
1.268     brouard  7978: /*  '' u 6:(($1==1 && $2==0  && $3==2 && $4==0) && (($5-$6) == 1947) ? $10/(1.-$22) : 1/0):5 with labels center boxed not*/
                   7979:            }else{
                   7980:              /* fprintf(ficgp,"%s ? $%d/(1.-$%d) : 1/0) t 'p%d%d' with line ", gplotcondition, \ */
                   7981:              fprintf(ficgp,"%s ? $%d : 1/0) t 'b%d%d' with line ", gplotcondition, \
                   7982:                      ioffset+(cpt-1)*(nlstate+1)+1+(i-1), cpt,i );
                   7983:            }
                   7984:          } /* end if covariate */
                   7985:        } /* nlstate */
                   7986:        fprintf(ficgp,"\nset out; unset label;\n");
                   7987:       } /* end cpt state*/
                   7988:     } /* end covariate */
1.296     brouard  7989:   } /* End if prevbcast */
1.268     brouard  7990:   
1.227     brouard  7991:   
1.238     brouard  7992:   /* 9eme writing MLE parameters */
                   7993:   fprintf(ficgp,"\n##############\n#9eme MLE estimated parameters\n#############\n");
1.126     brouard  7994:   for(i=1,jk=1; i <=nlstate; i++){
1.187     brouard  7995:     fprintf(ficgp,"# initial state %d\n",i);
1.126     brouard  7996:     for(k=1; k <=(nlstate+ndeath); k++){
                   7997:       if (k != i) {
1.227     brouard  7998:        fprintf(ficgp,"#   current state %d\n",k);
                   7999:        for(j=1; j <=ncovmodel; j++){
                   8000:          fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
                   8001:          jk++; 
                   8002:        }
                   8003:        fprintf(ficgp,"\n");
1.126     brouard  8004:       }
                   8005:     }
1.223     brouard  8006:   }
1.187     brouard  8007:   fprintf(ficgp,"##############\n#\n");
1.227     brouard  8008:   
1.145     brouard  8009:   /*goto avoid;*/
1.238     brouard  8010:   /* 10eme Graphics of probabilities or incidences using written MLE parameters */
                   8011:   fprintf(ficgp,"\n##############\n#10eme Graphics of probabilities or incidences\n#############\n");
1.187     brouard  8012:   fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
                   8013:   fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
                   8014:   fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
                   8015:   fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
                   8016:   fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8017:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8018:   fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8019:   fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
                   8020:   fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
                   8021:   fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
                   8022:   fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
                   8023:   fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
                   8024:   fprintf(ficgp,"#\n");
1.223     brouard  8025:   for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
1.238     brouard  8026:     fprintf(ficgp,"#Number of graphics: first is logit, 2nd is probabilities, third is incidences per year\n");
1.237     brouard  8027:     fprintf(ficgp,"#model=%s \n",model);
1.238     brouard  8028:     fprintf(ficgp,"# Type of graphic ng=%d\n",ng);
1.264     brouard  8029:     fprintf(ficgp,"#   k1=1 to 2^%d=%d\n",cptcoveff,m);/* to be checked */
                   8030:     for(k1=1; k1 <=m; k1++)  /* For each combination of covariate */
1.237     brouard  8031:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.264     brouard  8032:       if(m != 1 && TKresult[nres]!= k1)
1.237     brouard  8033:        continue;
1.264     brouard  8034:       fprintf(ficgp,"\n\n# Combination of dummy  k1=%d which is ",k1);
                   8035:       strcpy(gplotlabel,"(");
1.276     brouard  8036:       /*sprintf(gplotlabel+strlen(gplotlabel)," Dummy combination %d ",k1);*/
1.264     brouard  8037:       for (k=1; k<=cptcoveff; k++){    /* For each correspondig covariate value  */
                   8038:        lv= decodtabm(k1,k,cptcoveff); /* Should be the covariate value corresponding to k1 combination and kth covariate */
                   8039:        /* decodtabm(1,1,4) = 1 because h=1  k= (1) 1  1  1 */
                   8040:        /* decodtabm(1,2,4) = 1 because h=1  k=  1 (1) 1  1 */
                   8041:        /* decodtabm(13,3,4)= 2 because h=13 k=  1  1 (2) 2 */
                   8042:        vlv= nbcode[Tvaraff[k]][lv];
                   8043:        fprintf(ficgp," V%d=%d ",Tvaraff[k],vlv);
                   8044:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%d ",Tvaraff[k],vlv);
                   8045:       }
1.237     brouard  8046:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8047:        fprintf(ficgp," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.264     brouard  8048:        sprintf(gplotlabel+strlen(gplotlabel)," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.237     brouard  8049:       }        
1.264     brouard  8050:       strcpy(gplotlabel+strlen(gplotlabel),")");
1.237     brouard  8051:       fprintf(ficgp,"\n#\n");
1.264     brouard  8052:       fprintf(ficgp,"\nset out \"%s_%d-%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),k1,ng,nres);
1.276     brouard  8053:       fprintf(ficgp,"\nset key outside ");
                   8054:       /* fprintf(ficgp,"\nset label \"%s\" at graph 1.2,0.5 center rotate font \"Helvetica,12\"\n",gplotlabel); */
                   8055:       fprintf(ficgp,"\nset title \"%s\" font \"Helvetica,12\"\n",gplotlabel);
1.223     brouard  8056:       fprintf(ficgp,"\nset ter svg size 640, 480 ");
                   8057:       if (ng==1){
                   8058:        fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
                   8059:        fprintf(ficgp,"\nunset log y");
                   8060:       }else if (ng==2){
                   8061:        fprintf(ficgp,"\nset ylabel \"Probability\"\n");
                   8062:        fprintf(ficgp,"\nset log y");
                   8063:       }else if (ng==3){
                   8064:        fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
                   8065:        fprintf(ficgp,"\nset log y");
                   8066:       }else
                   8067:        fprintf(ficgp,"\nunset title ");
                   8068:       fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
                   8069:       i=1;
                   8070:       for(k2=1; k2<=nlstate; k2++) {
                   8071:        k3=i;
                   8072:        for(k=1; k<=(nlstate+ndeath); k++) {
                   8073:          if (k != k2){
                   8074:            switch( ng) {
                   8075:            case 1:
                   8076:              if(nagesqr==0)
                   8077:                fprintf(ficgp," p%d+p%d*x",i,i+1);
                   8078:              else /* nagesqr =1 */
                   8079:                fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8080:              break;
                   8081:            case 2: /* ng=2 */
                   8082:              if(nagesqr==0)
                   8083:                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                   8084:              else /* nagesqr =1 */
                   8085:                fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                   8086:              break;
                   8087:            case 3:
                   8088:              if(nagesqr==0)
                   8089:                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                   8090:              else /* nagesqr =1 */
                   8091:                fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                   8092:              break;
                   8093:            }
                   8094:            ij=1;/* To be checked else nbcode[0][0] wrong */
1.237     brouard  8095:            ijp=1; /* product no age */
                   8096:            /* for(j=3; j <=ncovmodel-nagesqr; j++) { */
                   8097:            for(j=1; j <=cptcovt; j++) { /* For each covariate of the simplified model */
1.223     brouard  8098:              /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
1.268     brouard  8099:              if(cptcovage >0){ /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8100:                if(j==Tage[ij]) { /* Product by age  To be looked at!!*/
                   8101:                  if(ij <=cptcovage) { /* V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1, 2 V5 and V1 */
                   8102:                    if(DummyV[j]==0){
                   8103:                      fprintf(ficgp,"+p%d*%d*x",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]);;
                   8104:                    }else{ /* quantitative */
                   8105:                      fprintf(ficgp,"+p%d*%f*x",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* Tqinvresult in decoderesult */
                   8106:                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8107:                    }
                   8108:                    ij++;
1.237     brouard  8109:                  }
1.268     brouard  8110:                } 
                   8111:              }else if(cptcovprod >0){
                   8112:                if(j==Tprod[ijp]) { /* */ 
                   8113:                  /* printf("Tprod[%d]=%d, j=%d\n", ij, Tprod[ijp], j); */
                   8114:                  if(ijp <=cptcovprod) { /* Product */
                   8115:                    if(DummyV[Tvard[ijp][1]]==0){/* Vn is dummy */
                   8116:                      if(DummyV[Tvard[ijp][2]]==0){/* Vn and Vm are dummy */
                   8117:                        /* fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],nbcode[Tvard[ijp][2]][codtabm(k1,j)]); */
                   8118:                        fprintf(ficgp,"+p%d*%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tinvresult[nres][Tvard[ijp][2]]);
                   8119:                      }else{ /* Vn is dummy and Vm is quanti */
                   8120:                        /* fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,nbcode[Tvard[ijp][1]][codtabm(k1,j)],Tqinvresult[nres][Tvard[ijp][2]]); */
                   8121:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8122:                      }
                   8123:                    }else{ /* Vn*Vm Vn is quanti */
                   8124:                      if(DummyV[Tvard[ijp][2]]==0){
                   8125:                        fprintf(ficgp,"+p%d*%d*%f",i+j+2+nagesqr-1,Tinvresult[nres][Tvard[ijp][2]],Tqinvresult[nres][Tvard[ijp][1]]);
                   8126:                      }else{ /* Both quanti */
                   8127:                        fprintf(ficgp,"+p%d*%f*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvard[ijp][1]],Tqinvresult[nres][Tvard[ijp][2]]);
                   8128:                      }
1.237     brouard  8129:                    }
1.268     brouard  8130:                    ijp++;
1.237     brouard  8131:                  }
1.268     brouard  8132:                } /* end Tprod */
1.237     brouard  8133:              } else{  /* simple covariate */
1.264     brouard  8134:                /* fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,nbcode[Tvar[j]][codtabm(k1,j)]); /\* Valgrind bug nbcode *\/ */
1.237     brouard  8135:                if(Dummy[j]==0){
                   8136:                  fprintf(ficgp,"+p%d*%d",i+j+2+nagesqr-1,Tinvresult[nres][Tvar[j]]); /*  */
                   8137:                }else{ /* quantitative */
                   8138:                  fprintf(ficgp,"+p%d*%f",i+j+2+nagesqr-1,Tqinvresult[nres][Tvar[j]]); /* */
1.264     brouard  8139:                  /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
1.223     brouard  8140:                }
1.237     brouard  8141:              } /* end simple */
                   8142:            } /* end j */
1.223     brouard  8143:          }else{
                   8144:            i=i-ncovmodel;
                   8145:            if(ng !=1 ) /* For logit formula of log p11 is more difficult to get */
                   8146:              fprintf(ficgp," (1.");
                   8147:          }
1.227     brouard  8148:          
1.223     brouard  8149:          if(ng != 1){
                   8150:            fprintf(ficgp,")/(1");
1.227     brouard  8151:            
1.264     brouard  8152:            for(cpt=1; cpt <=nlstate; cpt++){ 
1.223     brouard  8153:              if(nagesqr==0)
1.264     brouard  8154:                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1);
1.223     brouard  8155:              else /* nagesqr =1 */
1.264     brouard  8156:                fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(cpt-1)*ncovmodel,k3+(cpt-1)*ncovmodel+1,k3+(cpt-1)*ncovmodel+1+nagesqr);
1.217     brouard  8157:               
1.223     brouard  8158:              ij=1;
                   8159:              for(j=3; j <=ncovmodel-nagesqr; j++){
1.268     brouard  8160:                 if(cptcovage >0){ 
                   8161:                   if((j-2)==Tage[ij]) { /* Bug valgrind */
                   8162:                     if(ij <=cptcovage) { /* Bug valgrind */
                   8163:                       fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);
                   8164:                       /* fprintf(ficgp,"+p%d*%d*x",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,Tvar[j-2])]); */
                   8165:                       ij++;
                   8166:                     }
                   8167:                   }
                   8168:                 }else
                   8169:                   fprintf(ficgp,"+p%d*%d",k3+(cpt-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(k1,j-2)]);/* Valgrind bug nbcode */
1.223     brouard  8170:              }
                   8171:              fprintf(ficgp,")");
                   8172:            }
                   8173:            fprintf(ficgp,")");
                   8174:            if(ng ==2)
1.276     brouard  8175:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"p%d%d\" ", nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8176:            else /* ng= 3 */
1.276     brouard  8177:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"i%d%d\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8178:          }else{ /* end ng <> 1 */
                   8179:            if( k !=k2) /* logit p11 is hard to draw */
1.276     brouard  8180:              fprintf(ficgp," w l lw 2 lt (%d*%d+%d)%%%d+1 dt %d t \"logit(p%d%d)\" ",  nlstate+ndeath, k2, k, nlstate+ndeath, k2, k2,k);
1.223     brouard  8181:          }
                   8182:          if ((k+k2)!= (nlstate*2+ndeath) && ng != 1)
                   8183:            fprintf(ficgp,",");
                   8184:          if (ng == 1 && k!=k2 && (k+k2)!= (nlstate*2+ndeath))
                   8185:            fprintf(ficgp,",");
                   8186:          i=i+ncovmodel;
                   8187:        } /* end k */
                   8188:       } /* end k2 */
1.276     brouard  8189:       /* fprintf(ficgp,"\n set out; unset label;set key default;\n"); */
                   8190:       fprintf(ficgp,"\n set out; unset title;set key default;\n");
1.264     brouard  8191:     } /* end k1 */
1.223     brouard  8192:   } /* end ng */
                   8193:   /* avoid: */
                   8194:   fflush(ficgp); 
1.126     brouard  8195: }  /* end gnuplot */
                   8196: 
                   8197: 
                   8198: /*************** Moving average **************/
1.219     brouard  8199: /* int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav, double bageout, double fageout){ */
1.222     brouard  8200:  int movingaverage(double ***probs, double bage, double fage, double ***mobaverage, int mobilav){
1.218     brouard  8201:    
1.222     brouard  8202:    int i, cpt, cptcod;
                   8203:    int modcovmax =1;
                   8204:    int mobilavrange, mob;
                   8205:    int iage=0;
1.288     brouard  8206:    int firstA1=0, firstA2=0;
1.222     brouard  8207: 
1.266     brouard  8208:    double sum=0., sumr=0.;
1.222     brouard  8209:    double age;
1.266     brouard  8210:    double *sumnewp, *sumnewm, *sumnewmr;
                   8211:    double *agemingood, *agemaxgood; 
                   8212:    double *agemingoodr, *agemaxgoodr; 
1.222     brouard  8213:   
                   8214:   
1.278     brouard  8215:    /* modcovmax=2*cptcoveff;  Max number of modalities. We suppose  */
                   8216:    /*             a covariate has 2 modalities, should be equal to ncovcombmax   */
1.222     brouard  8217: 
                   8218:    sumnewp = vector(1,ncovcombmax);
                   8219:    sumnewm = vector(1,ncovcombmax);
1.266     brouard  8220:    sumnewmr = vector(1,ncovcombmax);
1.222     brouard  8221:    agemingood = vector(1,ncovcombmax); 
1.266     brouard  8222:    agemingoodr = vector(1,ncovcombmax);        
1.222     brouard  8223:    agemaxgood = vector(1,ncovcombmax);
1.266     brouard  8224:    agemaxgoodr = vector(1,ncovcombmax);
1.222     brouard  8225: 
                   8226:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
1.266     brouard  8227:      sumnewm[cptcod]=0.; sumnewmr[cptcod]=0.;
1.222     brouard  8228:      sumnewp[cptcod]=0.;
1.266     brouard  8229:      agemingood[cptcod]=0, agemingoodr[cptcod]=0;
                   8230:      agemaxgood[cptcod]=0, agemaxgoodr[cptcod]=0;
1.222     brouard  8231:    }
                   8232:    if (cptcovn<1) ncovcombmax=1; /* At least 1 pass */
                   8233:   
1.266     brouard  8234:    if(mobilav==-1 || mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
                   8235:      if(mobilav==1 || mobilav==-1) mobilavrange=5; /* default */
1.222     brouard  8236:      else mobilavrange=mobilav;
                   8237:      for (age=bage; age<=fage; age++)
                   8238:        for (i=1; i<=nlstate;i++)
                   8239:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++)
                   8240:           mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8241:      /* We keep the original values on the extreme ages bage, fage and for 
                   8242:        fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
                   8243:        we use a 5 terms etc. until the borders are no more concerned. 
                   8244:      */ 
                   8245:      for (mob=3;mob <=mobilavrange;mob=mob+2){
                   8246:        for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
1.266     brouard  8247:         for (cptcod=1;cptcod<=ncovcombmax;cptcod++){
                   8248:           sumnewm[cptcod]=0.;
                   8249:           for (i=1; i<=nlstate;i++){
1.222     brouard  8250:             mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                   8251:             for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   8252:               mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   8253:               mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                   8254:             }
                   8255:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
1.266     brouard  8256:             sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8257:           } /* end i */
                   8258:           if(sumnewm[cptcod] >1.e-3) mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/sumnewm[cptcod]; /* Rescaling to sum one */
                   8259:         } /* end cptcod */
1.222     brouard  8260:        }/* end age */
                   8261:      }/* end mob */
1.266     brouard  8262:    }else{
                   8263:      printf("Error internal in movingaverage, mobilav=%d.\n",mobilav);
1.222     brouard  8264:      return -1;
1.266     brouard  8265:    }
                   8266: 
                   8267:    for (cptcod=1;cptcod<=ncovcombmax;cptcod++){ /* for each combination */
1.222     brouard  8268:      /* for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ */
                   8269:      if(invalidvarcomb[cptcod]){
                   8270:        printf("\nCombination (%d) ignored because no cases \n",cptcod); 
                   8271:        continue;
                   8272:      }
1.219     brouard  8273: 
1.266     brouard  8274:      for (age=fage-(mob-1)/2; age>=bage+(mob-1)/2; age--){ /*looking for the youngest and oldest good age */
                   8275:        sumnewm[cptcod]=0.;
                   8276:        sumnewmr[cptcod]=0.;
                   8277:        for (i=1; i<=nlstate;i++){
                   8278:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8279:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8280:        }
                   8281:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8282:         agemingoodr[cptcod]=age;
                   8283:        }
                   8284:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8285:           agemingood[cptcod]=age;
                   8286:        }
                   8287:      } /* age */
                   8288:      for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){ /*looking for the youngest and oldest good age */
1.222     brouard  8289:        sumnewm[cptcod]=0.;
1.266     brouard  8290:        sumnewmr[cptcod]=0.;
1.222     brouard  8291:        for (i=1; i<=nlstate;i++){
                   8292:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8293:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8294:        }
                   8295:        if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8296:         agemaxgoodr[cptcod]=age;
1.222     brouard  8297:        }
                   8298:        if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
1.266     brouard  8299:         agemaxgood[cptcod]=age;
                   8300:        }
                   8301:      } /* age */
                   8302:      /* Thus we have agemingood and agemaxgood as well as goodr for raw (preobs) */
                   8303:      /* but they will change */
1.288     brouard  8304:      firstA1=0;firstA2=0;
1.266     brouard  8305:      for (age=fage-(mob-1)/2; age>=bage; age--){/* From oldest to youngest, filling up to the youngest */
                   8306:        sumnewm[cptcod]=0.;
                   8307:        sumnewmr[cptcod]=0.;
                   8308:        for (i=1; i<=nlstate;i++){
                   8309:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8310:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8311:        }
                   8312:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8313:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good without smoothing */
                   8314:           agemaxgoodr[cptcod]=age;  /* age min */
                   8315:           for (i=1; i<=nlstate;i++)
                   8316:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8317:         }else{ /* bad we change the value with the values of good ages */
                   8318:           for (i=1; i<=nlstate;i++){
                   8319:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgoodr[cptcod]][i][cptcod];
                   8320:           } /* i */
                   8321:         } /* end bad */
                   8322:        }else{
                   8323:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8324:           agemaxgood[cptcod]=age;
                   8325:         }else{ /* bad we change the value with the values of good ages */
                   8326:           for (i=1; i<=nlstate;i++){
                   8327:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod];
                   8328:           } /* i */
                   8329:         } /* end bad */
                   8330:        }/* end else */
                   8331:        sum=0.;sumr=0.;
                   8332:        for (i=1; i<=nlstate;i++){
                   8333:         sum+=mobaverage[(int)age][i][cptcod];
                   8334:         sumr+=probs[(int)age][i][cptcod];
                   8335:        }
                   8336:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.288     brouard  8337:         if(!firstA1){
                   8338:           firstA1=1;
                   8339:           printf("Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8340:         }
                   8341:         fprintf(ficlog,"Moving average A1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.266     brouard  8342:        } /* end bad */
                   8343:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8344:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.288     brouard  8345:         if(!firstA2){
                   8346:           firstA2=1;
                   8347:           printf("Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d. Others in log file...\n",cptcod,sumr, (int)age, (int)bage);
                   8348:         }
                   8349:         fprintf(ficlog,"Moving average A2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase bage=%d\n",cptcod,sumr, (int)age, (int)bage);
1.222     brouard  8350:        } /* end bad */
                   8351:      }/* age */
1.266     brouard  8352: 
                   8353:      for (age=bage+(mob-1)/2; age<=fage; age++){/* From youngest, finding the oldest wrong */
1.222     brouard  8354:        sumnewm[cptcod]=0.;
1.266     brouard  8355:        sumnewmr[cptcod]=0.;
1.222     brouard  8356:        for (i=1; i<=nlstate;i++){
                   8357:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
1.266     brouard  8358:         sumnewmr[cptcod]+=probs[(int)age][i][cptcod];
                   8359:        } 
                   8360:        if(mobilav==-1){ /* Forcing raw ages if good else agemingood */
                   8361:         if(fabs(sumnewmr[cptcod] - 1.) <= 1.e-3) { /* good */
                   8362:           agemingoodr[cptcod]=age;
                   8363:           for (i=1; i<=nlstate;i++)
                   8364:             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
                   8365:         }else{ /* bad we change the value with the values of good ages */
                   8366:           for (i=1; i<=nlstate;i++){
                   8367:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingoodr[cptcod]][i][cptcod];
                   8368:           } /* i */
                   8369:         } /* end bad */
                   8370:        }else{
                   8371:         if(fabs(sumnewm[cptcod] - 1.) <= 1.e-3) { /* good */
                   8372:           agemingood[cptcod]=age;
                   8373:         }else{ /* bad */
                   8374:           for (i=1; i<=nlstate;i++){
                   8375:             mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod];
                   8376:           } /* i */
                   8377:         } /* end bad */
                   8378:        }/* end else */
                   8379:        sum=0.;sumr=0.;
                   8380:        for (i=1; i<=nlstate;i++){
                   8381:         sum+=mobaverage[(int)age][i][cptcod];
                   8382:         sumr+=mobaverage[(int)age][i][cptcod];
1.222     brouard  8383:        }
1.266     brouard  8384:        if(fabs(sum - 1.) > 1.e-3) { /* bad */
1.268     brouard  8385:         printf("Moving average B1: For this combination of covariate cptcod=%d, we can't get a smoothed prevalence which sums to one (%f) at any descending age! age=%d, could you decrease fage=%d?\n",cptcod, sum, (int) age, (int)fage);
1.266     brouard  8386:        } /* end bad */
                   8387:        /* else{ /\* We found some ages summing to one, we will smooth the oldest *\/ */
                   8388:        if(fabs(sumr - 1.) > 1.e-3) { /* bad */
1.268     brouard  8389:         printf("Moving average B2: For this combination of covariate cptcod=%d, the raw prevalence doesn't sums to one (%f) even with smoothed values at young ages! age=%d, could you increase fage=%d\n",cptcod,sumr, (int)age, (int)fage);
1.222     brouard  8390:        } /* end bad */
                   8391:      }/* age */
1.266     brouard  8392: 
1.222     brouard  8393:                
                   8394:      for (age=bage; age<=fage; age++){
1.235     brouard  8395:        /* printf("%d %d ", cptcod, (int)age); */
1.222     brouard  8396:        sumnewp[cptcod]=0.;
                   8397:        sumnewm[cptcod]=0.;
                   8398:        for (i=1; i<=nlstate;i++){
                   8399:         sumnewp[cptcod]+=probs[(int)age][i][cptcod];
                   8400:         sumnewm[cptcod]+=mobaverage[(int)age][i][cptcod];
                   8401:         /* printf("%.4f %.4f ",probs[(int)age][i][cptcod], mobaverage[(int)age][i][cptcod]); */
                   8402:        }
                   8403:        /* printf("%.4f %.4f \n",sumnewp[cptcod], sumnewm[cptcod]); */
                   8404:      }
                   8405:      /* printf("\n"); */
                   8406:      /* } */
1.266     brouard  8407: 
1.222     brouard  8408:      /* brutal averaging */
1.266     brouard  8409:      /* for (i=1; i<=nlstate;i++){ */
                   8410:      /*   for (age=1; age<=bage; age++){ */
                   8411:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemingood[cptcod]][i][cptcod]; */
                   8412:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8413:      /*   }     */
                   8414:      /*   for (age=fage; age<=AGESUP; age++){ */
                   8415:      /*         mobaverage[(int)age][i][cptcod]=mobaverage[(int)agemaxgood[cptcod]][i][cptcod]; */
                   8416:      /*         /\* printf("age=%d i=%d cptcod=%d mobaverage=%.4f \n",(int)age,i, cptcod, mobaverage[(int)age][i][cptcod]); *\/ */
                   8417:      /*   } */
                   8418:      /* } /\* end i status *\/ */
                   8419:      /* for (i=nlstate+1; i<=nlstate+ndeath;i++){ */
                   8420:      /*   for (age=1; age<=AGESUP; age++){ */
                   8421:      /*         /\*printf("i=%d, age=%d, cptcod=%d\n",i, (int)age, cptcod);*\/ */
                   8422:      /*         mobaverage[(int)age][i][cptcod]=0.; */
                   8423:      /*   } */
                   8424:      /* } */
1.222     brouard  8425:    }/* end cptcod */
1.266     brouard  8426:    free_vector(agemaxgoodr,1, ncovcombmax);
                   8427:    free_vector(agemaxgood,1, ncovcombmax);
                   8428:    free_vector(agemingood,1, ncovcombmax);
                   8429:    free_vector(agemingoodr,1, ncovcombmax);
                   8430:    free_vector(sumnewmr,1, ncovcombmax);
1.222     brouard  8431:    free_vector(sumnewm,1, ncovcombmax);
                   8432:    free_vector(sumnewp,1, ncovcombmax);
                   8433:    return 0;
                   8434:  }/* End movingaverage */
1.218     brouard  8435:  
1.126     brouard  8436: 
1.296     brouard  8437:  
1.126     brouard  8438: /************** Forecasting ******************/
1.296     brouard  8439: /* void prevforecast(char fileres[], double dateintmean, double anprojd, double mprojd, double jprojd, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double anprojf, double p[], int cptcoveff)*/
                   8440: void prevforecast(char fileres[], double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double ***prev, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8441:   /* dateintemean, mean date of interviews
                   8442:      dateprojd, year, month, day of starting projection 
                   8443:      dateprojf date of end of projection;year of end of projection (same day and month as proj1).
1.126     brouard  8444:      agemin, agemax range of age
                   8445:      dateprev1 dateprev2 range of dates during which prevalence is computed
                   8446:   */
1.296     brouard  8447:   /* double anprojd, mprojd, jprojd; */
                   8448:   /* double anprojf, mprojf, jprojf; */
1.267     brouard  8449:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
1.126     brouard  8450:   double agec; /* generic age */
1.296     brouard  8451:   double agelim, ppij, yp,yp1,yp2;
1.126     brouard  8452:   double *popeffectif,*popcount;
                   8453:   double ***p3mat;
1.218     brouard  8454:   /* double ***mobaverage; */
1.126     brouard  8455:   char fileresf[FILENAMELENGTH];
                   8456: 
                   8457:   agelim=AGESUP;
1.211     brouard  8458:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8459:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8460:      We still use firstpass and lastpass as another selection.
                   8461:   */
1.214     brouard  8462:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8463:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
1.126     brouard  8464:  
1.201     brouard  8465:   strcpy(fileresf,"F_"); 
                   8466:   strcat(fileresf,fileresu);
1.126     brouard  8467:   if((ficresf=fopen(fileresf,"w"))==NULL) {
                   8468:     printf("Problem with forecast resultfile: %s\n", fileresf);
                   8469:     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
                   8470:   }
1.235     brouard  8471:   printf("\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
                   8472:   fprintf(ficlog,"\nComputing forecasting: result on file '%s', please wait... \n", fileresf);
1.126     brouard  8473: 
1.225     brouard  8474:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
1.126     brouard  8475: 
                   8476: 
                   8477:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8478:   if (stepm<=12) stepsize=1;
                   8479:   if(estepm < stepm){
                   8480:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8481:   }
1.270     brouard  8482:   else{
                   8483:     hstepm=estepm;   
                   8484:   }
                   8485:   if(estepm > stepm){ /* Yes every two year */
                   8486:     stepsize=2;
                   8487:   }
1.296     brouard  8488:   hstepm=hstepm/stepm;
1.126     brouard  8489: 
1.296     brouard  8490:   
                   8491:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8492:   /*                              fractional in yp1 *\/ */
                   8493:   /* aintmean=yp; */
                   8494:   /* yp2=modf((yp1*12),&yp); */
                   8495:   /* mintmean=yp; */
                   8496:   /* yp1=modf((yp2*30.5),&yp); */
                   8497:   /* jintmean=yp; */
                   8498:   /* if(jintmean==0) jintmean=1; */
                   8499:   /* if(mintmean==0) mintmean=1; */
1.126     brouard  8500: 
1.296     brouard  8501: 
                   8502:   /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */
                   8503:   /* date2dmy(dateprojd,&jprojd, &mprojd, &anprojd); */
                   8504:   /* date2dmy(dateprojf,&jprojf, &mprojf, &anprojf); */
1.227     brouard  8505:   i1=pow(2,cptcoveff);
1.126     brouard  8506:   if (cptcovn < 1){i1=1;}
                   8507:   
1.296     brouard  8508:   fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2); 
1.126     brouard  8509:   
                   8510:   fprintf(ficresf,"#****** Routine prevforecast **\n");
1.227     brouard  8511:   
1.126     brouard  8512: /*           if (h==(int)(YEARM*yearp)){ */
1.235     brouard  8513:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8514:   for(k=1; k<=i1;k++){
1.253     brouard  8515:     if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  8516:       continue;
1.227     brouard  8517:     if(invalidvarcomb[k]){
                   8518:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8519:       continue;
                   8520:     }
                   8521:     fprintf(ficresf,"\n#****** hpijx=probability over h years, hp.jx is weighted by observed prev \n#");
                   8522:     for(j=1;j<=cptcoveff;j++) {
                   8523:       fprintf(ficresf," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8524:     }
1.235     brouard  8525:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
1.238     brouard  8526:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
1.235     brouard  8527:     }
1.227     brouard  8528:     fprintf(ficresf," yearproj age");
                   8529:     for(j=1; j<=nlstate+ndeath;j++){ 
                   8530:       for(i=1; i<=nlstate;i++)               
                   8531:        fprintf(ficresf," p%d%d",i,j);
                   8532:       fprintf(ficresf," wp.%d",j);
                   8533:     }
1.296     brouard  8534:     for (yearp=0; yearp<=(anprojf-anprojd);yearp +=stepsize) {
1.227     brouard  8535:       fprintf(ficresf,"\n");
1.296     brouard  8536:       fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jprojd,mprojd,anprojd+yearp);   
1.270     brouard  8537:       /* for (agec=fage; agec>=(ageminpar-1); agec--){  */
                   8538:       for (agec=fage; agec>=(bage); agec--){ 
1.227     brouard  8539:        nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
                   8540:        nhstepm = nhstepm/hstepm; 
                   8541:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8542:        oldm=oldms;savm=savms;
1.268     brouard  8543:        /* We compute pii at age agec over nhstepm);*/
1.235     brouard  8544:        hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k,nres);
1.268     brouard  8545:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
1.227     brouard  8546:        for (h=0; h<=nhstepm; h++){
                   8547:          if (h*hstepm/YEARM*stepm ==yearp) {
1.268     brouard  8548:            break;
                   8549:          }
                   8550:        }
                   8551:        fprintf(ficresf,"\n");
                   8552:        for(j=1;j<=cptcoveff;j++) 
                   8553:          fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8554:        fprintf(ficresf,"%.f %.f ",anprojd+yearp,agec+h*hstepm/YEARM*stepm);
1.268     brouard  8555:        
                   8556:        for(j=1; j<=nlstate+ndeath;j++) {
                   8557:          ppij=0.;
                   8558:          for(i=1; i<=nlstate;i++) {
1.278     brouard  8559:            if (mobilav>=1)
                   8560:             ppij=ppij+p3mat[i][j][h]*prev[(int)agec][i][k];
                   8561:            else { /* even if mobilav==-1 we use mobaverage, probs may not sums to 1 */
                   8562:                ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k];
                   8563:            }
1.268     brouard  8564:            fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   8565:          } /* end i */
                   8566:          fprintf(ficresf," %.3f", ppij);
                   8567:        }/* end j */
1.227     brouard  8568:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8569:       } /* end agec */
1.266     brouard  8570:       /* diffyear=(int) anproj1+yearp-ageminpar-1; */
                   8571:       /*printf("Prevforecast %d+%d-%d=diffyear=%d\n",(int) anproj1, (int)yearp,(int)ageminpar,(int) anproj1-(int)ageminpar);*/
1.227     brouard  8572:     } /* end yearp */
                   8573:   } /* end  k */
1.219     brouard  8574:        
1.126     brouard  8575:   fclose(ficresf);
1.215     brouard  8576:   printf("End of Computing forecasting \n");
                   8577:   fprintf(ficlog,"End of Computing forecasting\n");
                   8578: 
1.126     brouard  8579: }
                   8580: 
1.269     brouard  8581: /************** Back Forecasting ******************/
1.296     brouard  8582:  /* void prevbackforecast(char fileres[], double ***prevacurrent, double anback1, double mback1, double jback1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anback2, double p[], int cptcoveff){ */
                   8583:  void prevbackforecast(char fileres[], double ***prevacurrent, double dateintmean, double dateprojd, double dateprojf, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double p[], int cptcoveff){
                   8584:   /* back1, year, month, day of starting backprojection
1.267     brouard  8585:      agemin, agemax range of age
                   8586:      dateprev1 dateprev2 range of dates during which prevalence is computed
1.269     brouard  8587:      anback2 year of end of backprojection (same day and month as back1).
                   8588:      prevacurrent and prev are prevalences.
1.267     brouard  8589:   */
                   8590:   int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1, k4, nres=0;
                   8591:   double agec; /* generic age */
1.302     brouard  8592:   double agelim, ppij, ppi, yp,yp1,yp2; /* ,jintmean,mintmean,aintmean;*/
1.267     brouard  8593:   double *popeffectif,*popcount;
                   8594:   double ***p3mat;
                   8595:   /* double ***mobaverage; */
                   8596:   char fileresfb[FILENAMELENGTH];
                   8597:  
1.268     brouard  8598:   agelim=AGEINF;
1.267     brouard  8599:   /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
                   8600:      in each health status at the date of interview (if between dateprev1 and dateprev2).
                   8601:      We still use firstpass and lastpass as another selection.
                   8602:   */
                   8603:   /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart,\ */
                   8604:   /*         firstpass, lastpass,  stepm,  weightopt, model); */
                   8605: 
                   8606:   /*Do we need to compute prevalence again?*/
                   8607: 
                   8608:   /* prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
                   8609:   
                   8610:   strcpy(fileresfb,"FB_");
                   8611:   strcat(fileresfb,fileresu);
                   8612:   if((ficresfb=fopen(fileresfb,"w"))==NULL) {
                   8613:     printf("Problem with back forecast resultfile: %s\n", fileresfb);
                   8614:     fprintf(ficlog,"Problem with back forecast resultfile: %s\n", fileresfb);
                   8615:   }
                   8616:   printf("\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8617:   fprintf(ficlog,"\nComputing back forecasting: result on file '%s', please wait... \n", fileresfb);
                   8618:   
                   8619:   if (cptcoveff==0) ncodemax[cptcoveff]=1;
                   8620:   
                   8621:    
                   8622:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   8623:   if (stepm<=12) stepsize=1;
                   8624:   if(estepm < stepm){
                   8625:     printf ("Problem %d lower than %d\n",estepm, stepm);
                   8626:   }
1.270     brouard  8627:   else{
                   8628:     hstepm=estepm;   
                   8629:   }
                   8630:   if(estepm >= stepm){ /* Yes every two year */
                   8631:     stepsize=2;
                   8632:   }
1.267     brouard  8633:   
                   8634:   hstepm=hstepm/stepm;
1.296     brouard  8635:   /* yp1=modf(dateintmean,&yp);/\* extracts integral of datemean in yp  and */
                   8636:   /*                              fractional in yp1 *\/ */
                   8637:   /* aintmean=yp; */
                   8638:   /* yp2=modf((yp1*12),&yp); */
                   8639:   /* mintmean=yp; */
                   8640:   /* yp1=modf((yp2*30.5),&yp); */
                   8641:   /* jintmean=yp; */
                   8642:   /* if(jintmean==0) jintmean=1; */
                   8643:   /* if(mintmean==0) jintmean=1; */
1.267     brouard  8644:   
                   8645:   i1=pow(2,cptcoveff);
                   8646:   if (cptcovn < 1){i1=1;}
                   8647:   
1.296     brouard  8648:   fprintf(ficresfb,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
                   8649:   printf("# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jintmean,mintmean,aintmean,dateintmean,dateprev1,dateprev2);
1.267     brouard  8650:   
                   8651:   fprintf(ficresfb,"#****** Routine prevbackforecast **\n");
                   8652:   
                   8653:   for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8654:   for(k=1; k<=i1;k++){
                   8655:     if(i1 != 1 && TKresult[nres]!= k)
                   8656:       continue;
                   8657:     if(invalidvarcomb[k]){
                   8658:       printf("\nCombination (%d) projection ignored because no cases \n",k); 
                   8659:       continue;
                   8660:     }
1.268     brouard  8661:     fprintf(ficresfb,"\n#****** hbijx=probability over h years, hb.jx is weighted by observed prev \n#");
1.267     brouard  8662:     for(j=1;j<=cptcoveff;j++) {
                   8663:       fprintf(ficresfb," V%d (=) %d",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8664:     }
                   8665:     for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   8666:       fprintf(ficresf," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   8667:     }
                   8668:     fprintf(ficresfb," yearbproj age");
                   8669:     for(j=1; j<=nlstate+ndeath;j++){
                   8670:       for(i=1; i<=nlstate;i++)
1.268     brouard  8671:        fprintf(ficresfb," b%d%d",i,j);
                   8672:       fprintf(ficresfb," b.%d",j);
1.267     brouard  8673:     }
1.296     brouard  8674:     for (yearp=0; yearp>=(anbackf-anbackd);yearp -=stepsize) {
1.267     brouard  8675:       /* for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) {  */
                   8676:       fprintf(ficresfb,"\n");
1.296     brouard  8677:       fprintf(ficresfb,"\n# Back Forecasting at date %.lf/%.lf/%.lf ",jbackd,mbackd,anbackd+yearp);
1.273     brouard  8678:       /* printf("\n# Back Forecasting at date %.lf/%.lf/%.lf ",jback1,mback1,anback1+yearp); */
1.270     brouard  8679:       /* for (agec=bage; agec<=agemax-1; agec++){  /\* testing *\/ */
                   8680:       for (agec=bage; agec<=fage; agec++){  /* testing */
1.268     brouard  8681:        /* We compute bij at age agec over nhstepm, nhstepm decreases when agec increases because of agemax;*/
1.271     brouard  8682:        nhstepm=(int) (agec-agelim) *YEARM/stepm;/*     nhstepm=(int) rint((agec-agelim)*YEARM/stepm);*/
1.267     brouard  8683:        nhstepm = nhstepm/hstepm;
                   8684:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8685:        oldm=oldms;savm=savms;
1.268     brouard  8686:        /* computes hbxij at age agec over 1 to nhstepm */
1.271     brouard  8687:        /* printf("####prevbackforecast debug  agec=%.2f nhstepm=%d\n",agec, nhstepm);fflush(stdout); */
1.267     brouard  8688:        hbxij(p3mat,nhstepm,agec,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.268     brouard  8689:        /* hpxij(p3mat,nhstepm,agec,hstepm,p,             nlstate,stepm,oldm,savm, k,nres); */
                   8690:        /* Then we print p3mat for h corresponding to the right agec+h*stepms=yearp */
                   8691:        /* printf(" agec=%.2f\n",agec);fflush(stdout); */
1.267     brouard  8692:        for (h=0; h<=nhstepm; h++){
1.268     brouard  8693:          if (h*hstepm/YEARM*stepm ==-yearp) {
                   8694:            break;
                   8695:          }
                   8696:        }
                   8697:        fprintf(ficresfb,"\n");
                   8698:        for(j=1;j<=cptcoveff;j++)
                   8699:          fprintf(ficresfb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.296     brouard  8700:        fprintf(ficresfb,"%.f %.f ",anbackd+yearp,agec-h*hstepm/YEARM*stepm);
1.268     brouard  8701:        for(i=1; i<=nlstate+ndeath;i++) {
                   8702:          ppij=0.;ppi=0.;
                   8703:          for(j=1; j<=nlstate;j++) {
                   8704:            /* if (mobilav==1) */
1.269     brouard  8705:            ppij=ppij+p3mat[i][j][h]*prevacurrent[(int)agec][j][k];
                   8706:            ppi=ppi+prevacurrent[(int)agec][j][k];
                   8707:            /* ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][j][k]; */
                   8708:            /* ppi=ppi+mobaverage[(int)agec][j][k]; */
1.267     brouard  8709:              /* else { */
                   8710:              /*        ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][k]; */
                   8711:              /* } */
1.268     brouard  8712:            fprintf(ficresfb," %.3f", p3mat[i][j][h]);
                   8713:          } /* end j */
                   8714:          if(ppi <0.99){
                   8715:            printf("Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8716:            fprintf(ficlog,"Error in prevbackforecast, prevalence doesn't sum to 1 for state %d: %3f\n",i, ppi);
                   8717:          }
                   8718:          fprintf(ficresfb," %.3f", ppij);
                   8719:        }/* end j */
1.267     brouard  8720:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   8721:       } /* end agec */
                   8722:     } /* end yearp */
                   8723:   } /* end k */
1.217     brouard  8724:   
1.267     brouard  8725:   /* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
1.217     brouard  8726:   
1.267     brouard  8727:   fclose(ficresfb);
                   8728:   printf("End of Computing Back forecasting \n");
                   8729:   fprintf(ficlog,"End of Computing Back forecasting\n");
1.218     brouard  8730:        
1.267     brouard  8731: }
1.217     brouard  8732: 
1.269     brouard  8733: /* Variance of prevalence limit: varprlim */
                   8734:  void varprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **prlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
1.288     brouard  8735:     /*------- Variance of forward period (stable) prevalence------*/   
1.269     brouard  8736:  
                   8737:    char fileresvpl[FILENAMELENGTH];  
                   8738:    FILE *ficresvpl;
                   8739:    double **oldm, **savm;
                   8740:    double **varpl; /* Variances of prevalence limits by age */   
                   8741:    int i1, k, nres, j ;
                   8742:    
                   8743:     strcpy(fileresvpl,"VPL_");
                   8744:     strcat(fileresvpl,fileresu);
                   8745:     if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
1.288     brouard  8746:       printf("Problem with variance of forward period (stable) prevalence  resultfile: %s\n", fileresvpl);
1.269     brouard  8747:       exit(0);
                   8748:     }
1.288     brouard  8749:     printf("Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
                   8750:     fprintf(ficlog, "Computing Variance-covariance of forward period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
1.269     brouard  8751:     
                   8752:     /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
                   8753:       for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
                   8754:     
                   8755:     i1=pow(2,cptcoveff);
                   8756:     if (cptcovn < 1){i1=1;}
                   8757: 
                   8758:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8759:     for(k=1; k<=i1;k++){
                   8760:       if(i1 != 1 && TKresult[nres]!= k)
                   8761:        continue;
                   8762:       fprintf(ficresvpl,"\n#****** ");
                   8763:       printf("\n#****** ");
                   8764:       fprintf(ficlog,"\n#****** ");
                   8765:       for(j=1;j<=cptcoveff;j++) {
                   8766:        fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8767:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8768:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8769:       }
                   8770:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8771:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8772:        fprintf(ficresvpl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8773:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8774:       }        
                   8775:       fprintf(ficresvpl,"******\n");
                   8776:       printf("******\n");
                   8777:       fprintf(ficlog,"******\n");
                   8778:       
                   8779:       varpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8780:       oldm=oldms;savm=savms;
                   8781:       varprevlim(fileresvpl, ficresvpl, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, ncvyearp, k, strstart, nres);
                   8782:       free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
                   8783:       /*}*/
                   8784:     }
                   8785:     
                   8786:     fclose(ficresvpl);
1.288     brouard  8787:     printf("done variance-covariance of forward period prevalence\n");fflush(stdout);
                   8788:     fprintf(ficlog,"done variance-covariance of forward period prevalence\n");fflush(ficlog);
1.269     brouard  8789: 
                   8790:  }
                   8791: /* Variance of back prevalence: varbprlim */
                   8792:  void varbprlim(char fileresu[], int nresult, double ***prevacurrent, int mobilavproj, double bage, double fage, double **bprlim, int *ncvyearp, double ftolpl, double p[], double **matcov, double *delti, int stepm, int cptcoveff){
                   8793:       /*------- Variance of back (stable) prevalence------*/
                   8794: 
                   8795:    char fileresvbl[FILENAMELENGTH];  
                   8796:    FILE  *ficresvbl;
                   8797: 
                   8798:    double **oldm, **savm;
                   8799:    double **varbpl; /* Variances of back prevalence limits by age */   
                   8800:    int i1, k, nres, j ;
                   8801: 
                   8802:    strcpy(fileresvbl,"VBL_");
                   8803:    strcat(fileresvbl,fileresu);
                   8804:    if((ficresvbl=fopen(fileresvbl,"w"))==NULL) {
                   8805:      printf("Problem with variance of back (stable) prevalence  resultfile: %s\n", fileresvbl);
                   8806:      exit(0);
                   8807:    }
                   8808:    printf("Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(stdout);
                   8809:    fprintf(ficlog, "Computing Variance-covariance of back (stable) prevalence: file '%s' ...", fileresvbl);fflush(ficlog);
                   8810:    
                   8811:    
                   8812:    i1=pow(2,cptcoveff);
                   8813:    if (cptcovn < 1){i1=1;}
                   8814:    
                   8815:    for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   8816:      for(k=1; k<=i1;k++){
                   8817:        if(i1 != 1 && TKresult[nres]!= k)
                   8818:         continue;
                   8819:        fprintf(ficresvbl,"\n#****** ");
                   8820:        printf("\n#****** ");
                   8821:        fprintf(ficlog,"\n#****** ");
                   8822:        for(j=1;j<=cptcoveff;j++) {
                   8823:         fprintf(ficresvbl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8824:         fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8825:         printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   8826:        }
                   8827:        for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   8828:         printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8829:         fprintf(ficresvbl," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8830:         fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   8831:        }
                   8832:        fprintf(ficresvbl,"******\n");
                   8833:        printf("******\n");
                   8834:        fprintf(ficlog,"******\n");
                   8835:        
                   8836:        varbpl=matrix(1,nlstate,(int) bage, (int) fage);
                   8837:        oldm=oldms;savm=savms;
                   8838:        
                   8839:        varbrevlim(fileresvbl, ficresvbl, varbpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, bprlim, ftolpl, mobilavproj, ncvyearp, k, strstart, nres);
                   8840:        free_matrix(varbpl,1,nlstate,(int) bage, (int)fage);
                   8841:        /*}*/
                   8842:      }
                   8843:    
                   8844:    fclose(ficresvbl);
                   8845:    printf("done variance-covariance of back prevalence\n");fflush(stdout);
                   8846:    fprintf(ficlog,"done variance-covariance of back prevalence\n");fflush(ficlog);
                   8847: 
                   8848:  } /* End of varbprlim */
                   8849: 
1.126     brouard  8850: /************** Forecasting *****not tested NB*************/
1.227     brouard  8851: /* void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2s, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){ */
1.126     brouard  8852:   
1.227     brouard  8853: /*   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h; */
                   8854: /*   int *popage; */
                   8855: /*   double calagedatem, agelim, kk1, kk2; */
                   8856: /*   double *popeffectif,*popcount; */
                   8857: /*   double ***p3mat,***tabpop,***tabpopprev; */
                   8858: /*   /\* double ***mobaverage; *\/ */
                   8859: /*   char filerespop[FILENAMELENGTH]; */
1.126     brouard  8860: 
1.227     brouard  8861: /*   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8862: /*   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   8863: /*   agelim=AGESUP; */
                   8864: /*   calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM; */
1.126     brouard  8865:   
1.227     brouard  8866: /*   prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass); */
1.126     brouard  8867:   
                   8868:   
1.227     brouard  8869: /*   strcpy(filerespop,"POP_");  */
                   8870: /*   strcat(filerespop,fileresu); */
                   8871: /*   if((ficrespop=fopen(filerespop,"w"))==NULL) { */
                   8872: /*     printf("Problem with forecast resultfile: %s\n", filerespop); */
                   8873: /*     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop); */
                   8874: /*   } */
                   8875: /*   printf("Computing forecasting: result on file '%s' \n", filerespop); */
                   8876: /*   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop); */
1.126     brouard  8877: 
1.227     brouard  8878: /*   if (cptcoveff==0) ncodemax[cptcoveff]=1; */
1.126     brouard  8879: 
1.227     brouard  8880: /*   /\* if (mobilav!=0) { *\/ */
                   8881: /*   /\*   mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
                   8882: /*   /\*   if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){ *\/ */
                   8883: /*   /\*     fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8884: /*   /\*     printf(" Error in movingaverage mobilav=%d\n",mobilav); *\/ */
                   8885: /*   /\*   } *\/ */
                   8886: /*   /\* } *\/ */
1.126     brouard  8887: 
1.227     brouard  8888: /*   stepsize=(int) (stepm+YEARM-1)/YEARM; */
                   8889: /*   if (stepm<=12) stepsize=1; */
1.126     brouard  8890:   
1.227     brouard  8891: /*   agelim=AGESUP; */
1.126     brouard  8892:   
1.227     brouard  8893: /*   hstepm=1; */
                   8894: /*   hstepm=hstepm/stepm;  */
1.218     brouard  8895:        
1.227     brouard  8896: /*   if (popforecast==1) { */
                   8897: /*     if((ficpop=fopen(popfile,"r"))==NULL) { */
                   8898: /*       printf("Problem with population file : %s\n",popfile);exit(0); */
                   8899: /*       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0); */
                   8900: /*     }  */
                   8901: /*     popage=ivector(0,AGESUP); */
                   8902: /*     popeffectif=vector(0,AGESUP); */
                   8903: /*     popcount=vector(0,AGESUP); */
1.126     brouard  8904:     
1.227     brouard  8905: /*     i=1;    */
                   8906: /*     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1; */
1.218     brouard  8907:     
1.227     brouard  8908: /*     imx=i; */
                   8909: /*     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i]; */
                   8910: /*   } */
1.218     brouard  8911:   
1.227     brouard  8912: /*   for(cptcov=1,k=0;cptcov<=i2;cptcov++){ */
                   8913: /*     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){ */
                   8914: /*       k=k+1; */
                   8915: /*       fprintf(ficrespop,"\n#******"); */
                   8916: /*       for(j=1;j<=cptcoveff;j++) { */
                   8917: /*     fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */
                   8918: /*       } */
                   8919: /*       fprintf(ficrespop,"******\n"); */
                   8920: /*       fprintf(ficrespop,"# Age"); */
                   8921: /*       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j); */
                   8922: /*       if (popforecast==1)  fprintf(ficrespop," [Population]"); */
1.126     brouard  8923:       
1.227     brouard  8924: /*       for (cpt=0; cpt<=0;cpt++) {  */
                   8925: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
1.126     brouard  8926:        
1.227     brouard  8927: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8928: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8929: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8930:          
1.227     brouard  8931: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8932: /*       oldm=oldms;savm=savms; */
                   8933: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.218     brouard  8934:          
1.227     brouard  8935: /*       for (h=0; h<=nhstepm; h++){ */
                   8936: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8937: /*           fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8938: /*         }  */
                   8939: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8940: /*           kk1=0.;kk2=0; */
                   8941: /*           for(i=1; i<=nlstate;i++) {               */
                   8942: /*             if (mobilav==1)  */
                   8943: /*               kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod]; */
                   8944: /*             else { */
                   8945: /*               kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod]; */
                   8946: /*             } */
                   8947: /*           } */
                   8948: /*           if (h==(int)(calagedatem+12*cpt)){ */
                   8949: /*             tabpop[(int)(agedeb)][j][cptcod]=kk1; */
                   8950: /*             /\*fprintf(ficrespop," %.3f", kk1); */
                   8951: /*               if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*\/ */
                   8952: /*           } */
                   8953: /*         } */
                   8954: /*         for(i=1; i<=nlstate;i++){ */
                   8955: /*           kk1=0.; */
                   8956: /*           for(j=1; j<=nlstate;j++){ */
                   8957: /*             kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  */
                   8958: /*           } */
                   8959: /*           tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)]; */
                   8960: /*         } */
1.218     brouard  8961:            
1.227     brouard  8962: /*         if (h==(int)(calagedatem+12*cpt)) */
                   8963: /*           for(j=1; j<=nlstate;j++)  */
                   8964: /*             fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]); */
                   8965: /*       } */
                   8966: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8967: /*     } */
                   8968: /*       } */
1.218     brouard  8969:       
1.227     brouard  8970: /*       /\******\/ */
1.218     brouard  8971:       
1.227     brouard  8972: /*       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {  */
                   8973: /*     fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);    */
                   8974: /*     for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){  */
                   8975: /*       nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);  */
                   8976: /*       nhstepm = nhstepm/hstepm;  */
1.126     brouard  8977:          
1.227     brouard  8978: /*       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8979: /*       oldm=oldms;savm=savms; */
                   8980: /*       hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
                   8981: /*       for (h=0; h<=nhstepm; h++){ */
                   8982: /*         if (h==(int) (calagedatem+YEARM*cpt)) { */
                   8983: /*           fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm); */
                   8984: /*         }  */
                   8985: /*         for(j=1; j<=nlstate+ndeath;j++) { */
                   8986: /*           kk1=0.;kk2=0; */
                   8987: /*           for(i=1; i<=nlstate;i++) {               */
                   8988: /*             kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];     */
                   8989: /*           } */
                   8990: /*           if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);         */
                   8991: /*         } */
                   8992: /*       } */
                   8993: /*       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); */
                   8994: /*     } */
                   8995: /*       } */
                   8996: /*     }  */
                   8997: /*   } */
1.218     brouard  8998:   
1.227     brouard  8999: /*   /\* if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); *\/ */
1.218     brouard  9000:   
1.227     brouard  9001: /*   if (popforecast==1) { */
                   9002: /*     free_ivector(popage,0,AGESUP); */
                   9003: /*     free_vector(popeffectif,0,AGESUP); */
                   9004: /*     free_vector(popcount,0,AGESUP); */
                   9005: /*   } */
                   9006: /*   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9007: /*   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX); */
                   9008: /*   fclose(ficrespop); */
                   9009: /* } /\* End of popforecast *\/ */
1.218     brouard  9010:  
1.126     brouard  9011: int fileappend(FILE *fichier, char *optionfich)
                   9012: {
                   9013:   if((fichier=fopen(optionfich,"a"))==NULL) {
                   9014:     printf("Problem with file: %s\n", optionfich);
                   9015:     fprintf(ficlog,"Problem with file: %s\n", optionfich);
                   9016:     return (0);
                   9017:   }
                   9018:   fflush(fichier);
                   9019:   return (1);
                   9020: }
                   9021: 
                   9022: 
                   9023: /**************** function prwizard **********************/
                   9024: void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
                   9025: {
                   9026: 
                   9027:   /* Wizard to print covariance matrix template */
                   9028: 
1.164     brouard  9029:   char ca[32], cb[32];
                   9030:   int i,j, k, li, lj, lk, ll, jj, npar, itimes;
1.126     brouard  9031:   int numlinepar;
                   9032: 
                   9033:   printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9034:   fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   9035:   for(i=1; i <=nlstate; i++){
                   9036:     jj=0;
                   9037:     for(j=1; j <=nlstate+ndeath; j++){
                   9038:       if(j==i) continue;
                   9039:       jj++;
                   9040:       /*ca[0]= k+'a'-1;ca[1]='\0';*/
                   9041:       printf("%1d%1d",i,j);
                   9042:       fprintf(ficparo,"%1d%1d",i,j);
                   9043:       for(k=1; k<=ncovmodel;k++){
                   9044:        /*        printf(" %lf",param[i][j][k]); */
                   9045:        /*        fprintf(ficparo," %lf",param[i][j][k]); */
                   9046:        printf(" 0.");
                   9047:        fprintf(ficparo," 0.");
                   9048:       }
                   9049:       printf("\n");
                   9050:       fprintf(ficparo,"\n");
                   9051:     }
                   9052:   }
                   9053:   printf("# Scales (for hessian or gradient estimation)\n");
                   9054:   fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
                   9055:   npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
                   9056:   for(i=1; i <=nlstate; i++){
                   9057:     jj=0;
                   9058:     for(j=1; j <=nlstate+ndeath; j++){
                   9059:       if(j==i) continue;
                   9060:       jj++;
                   9061:       fprintf(ficparo,"%1d%1d",i,j);
                   9062:       printf("%1d%1d",i,j);
                   9063:       fflush(stdout);
                   9064:       for(k=1; k<=ncovmodel;k++){
                   9065:        /*      printf(" %le",delti3[i][j][k]); */
                   9066:        /*      fprintf(ficparo," %le",delti3[i][j][k]); */
                   9067:        printf(" 0.");
                   9068:        fprintf(ficparo," 0.");
                   9069:       }
                   9070:       numlinepar++;
                   9071:       printf("\n");
                   9072:       fprintf(ficparo,"\n");
                   9073:     }
                   9074:   }
                   9075:   printf("# Covariance matrix\n");
                   9076: /* # 121 Var(a12)\n\ */
                   9077: /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9078: /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   9079: /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   9080: /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   9081: /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   9082: /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   9083: /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   9084:   fflush(stdout);
                   9085:   fprintf(ficparo,"# Covariance matrix\n");
                   9086:   /* # 121 Var(a12)\n\ */
                   9087:   /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   9088:   /* #   ...\n\ */
                   9089:   /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
                   9090:   
                   9091:   for(itimes=1;itimes<=2;itimes++){
                   9092:     jj=0;
                   9093:     for(i=1; i <=nlstate; i++){
                   9094:       for(j=1; j <=nlstate+ndeath; j++){
                   9095:        if(j==i) continue;
                   9096:        for(k=1; k<=ncovmodel;k++){
                   9097:          jj++;
                   9098:          ca[0]= k+'a'-1;ca[1]='\0';
                   9099:          if(itimes==1){
                   9100:            printf("#%1d%1d%d",i,j,k);
                   9101:            fprintf(ficparo,"#%1d%1d%d",i,j,k);
                   9102:          }else{
                   9103:            printf("%1d%1d%d",i,j,k);
                   9104:            fprintf(ficparo,"%1d%1d%d",i,j,k);
                   9105:            /*  printf(" %.5le",matcov[i][j]); */
                   9106:          }
                   9107:          ll=0;
                   9108:          for(li=1;li <=nlstate; li++){
                   9109:            for(lj=1;lj <=nlstate+ndeath; lj++){
                   9110:              if(lj==li) continue;
                   9111:              for(lk=1;lk<=ncovmodel;lk++){
                   9112:                ll++;
                   9113:                if(ll<=jj){
                   9114:                  cb[0]= lk +'a'-1;cb[1]='\0';
                   9115:                  if(ll<jj){
                   9116:                    if(itimes==1){
                   9117:                      printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9118:                      fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   9119:                    }else{
                   9120:                      printf(" 0.");
                   9121:                      fprintf(ficparo," 0.");
                   9122:                    }
                   9123:                  }else{
                   9124:                    if(itimes==1){
                   9125:                      printf(" Var(%s%1d%1d)",ca,i,j);
                   9126:                      fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                   9127:                    }else{
                   9128:                      printf(" 0.");
                   9129:                      fprintf(ficparo," 0.");
                   9130:                    }
                   9131:                  }
                   9132:                }
                   9133:              } /* end lk */
                   9134:            } /* end lj */
                   9135:          } /* end li */
                   9136:          printf("\n");
                   9137:          fprintf(ficparo,"\n");
                   9138:          numlinepar++;
                   9139:        } /* end k*/
                   9140:       } /*end j */
                   9141:     } /* end i */
                   9142:   } /* end itimes */
                   9143: 
                   9144: } /* end of prwizard */
                   9145: /******************* Gompertz Likelihood ******************************/
                   9146: double gompertz(double x[])
                   9147: { 
1.302     brouard  9148:   double A=0.0,B=0.,L=0.0,sump=0.,num=0.;
1.126     brouard  9149:   int i,n=0; /* n is the size of the sample */
                   9150: 
1.220     brouard  9151:   for (i=1;i<=imx ; i++) {
1.126     brouard  9152:     sump=sump+weight[i];
                   9153:     /*    sump=sump+1;*/
                   9154:     num=num+1;
                   9155:   }
1.302     brouard  9156:   L=0.0;
                   9157:   /* agegomp=AGEGOMP; */
1.126     brouard  9158:   /* for (i=0; i<=imx; i++) 
                   9159:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9160: 
1.302     brouard  9161:   for (i=1;i<=imx ; i++) {
                   9162:     /* mu(a)=mu(agecomp)*exp(teta*(age-agegomp))
                   9163:        mu(a)=x[1]*exp(x[2]*(age-agegomp)); x[1] and x[2] are per year.
                   9164:      * L= Product mu(agedeces)exp(-\int_ageexam^agedc mu(u) du ) for a death between agedc (in month) 
                   9165:      *   and agedc +1 month, cens[i]=0: log(x[1]/YEARM)
                   9166:      * +
                   9167:      * exp(-\int_ageexam^agecens mu(u) du ) when censored, cens[i]=1
                   9168:      */
                   9169:      if (wav[i] > 1 || agedc[i] < AGESUP) {
                   9170:        if (cens[i] == 1){
                   9171:         A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
                   9172:        } else if (cens[i] == 0){
1.126     brouard  9173:        A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
1.302     brouard  9174:          +log(x[1]/YEARM) +x[2]*(agedc[i]-agegomp)+log(YEARM);
                   9175:       } else
                   9176:         printf("Gompertz cens[%d] neither 1 nor 0\n",i);
1.126     brouard  9177:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
1.302     brouard  9178:        L=L+A*weight[i];
1.126     brouard  9179:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
1.302     brouard  9180:      }
                   9181:   }
1.126     brouard  9182: 
1.302     brouard  9183:   /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
1.126     brouard  9184:  
                   9185:   return -2*L*num/sump;
                   9186: }
                   9187: 
1.136     brouard  9188: #ifdef GSL
                   9189: /******************* Gompertz_f Likelihood ******************************/
                   9190: double gompertz_f(const gsl_vector *v, void *params)
                   9191: { 
1.302     brouard  9192:   double A=0.,B=0.,LL=0.0,sump=0.,num=0.;
1.136     brouard  9193:   double *x= (double *) v->data;
                   9194:   int i,n=0; /* n is the size of the sample */
                   9195: 
                   9196:   for (i=0;i<=imx-1 ; i++) {
                   9197:     sump=sump+weight[i];
                   9198:     /*    sump=sump+1;*/
                   9199:     num=num+1;
                   9200:   }
                   9201:  
                   9202:  
                   9203:   /* for (i=0; i<=imx; i++) 
                   9204:      if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
                   9205:   printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
                   9206:   for (i=1;i<=imx ; i++)
                   9207:     {
                   9208:       if (cens[i] == 1 && wav[i]>1)
                   9209:        A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
                   9210:       
                   9211:       if (cens[i] == 0 && wav[i]>1)
                   9212:        A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                   9213:             +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
                   9214:       
                   9215:       /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
                   9216:       if (wav[i] > 1 ) { /* ??? */
                   9217:        LL=LL+A*weight[i];
                   9218:        /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
                   9219:       }
                   9220:     }
                   9221: 
                   9222:  /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
                   9223:   printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
                   9224:  
                   9225:   return -2*LL*num/sump;
                   9226: }
                   9227: #endif
                   9228: 
1.126     brouard  9229: /******************* Printing html file ***********/
1.201     brouard  9230: void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
1.126     brouard  9231:                  int lastpass, int stepm, int weightopt, char model[],\
                   9232:                  int imx,  double p[],double **matcov,double agemortsup){
                   9233:   int i,k;
                   9234: 
                   9235:   fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
                   9236:   fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
                   9237:   for (i=1;i<=2;i++) 
                   9238:     fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.199     brouard  9239:   fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
1.126     brouard  9240:   fprintf(fichtm,"</ul>");
                   9241: 
                   9242: fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
                   9243: 
                   9244:  fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
                   9245: 
                   9246:  for (k=agegomp;k<(agemortsup-2);k++) 
                   9247:    fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   9248: 
                   9249:  
                   9250:   fflush(fichtm);
                   9251: }
                   9252: 
                   9253: /******************* Gnuplot file **************/
1.201     brouard  9254: void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
1.126     brouard  9255: 
                   9256:   char dirfileres[132],optfileres[132];
1.164     brouard  9257: 
1.126     brouard  9258:   int ng;
                   9259: 
                   9260: 
                   9261:   /*#ifdef windows */
                   9262:   fprintf(ficgp,"cd \"%s\" \n",pathc);
                   9263:     /*#endif */
                   9264: 
                   9265: 
                   9266:   strcpy(dirfileres,optionfilefiname);
                   9267:   strcpy(optfileres,"vpl");
1.199     brouard  9268:   fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
1.126     brouard  9269:   fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
1.199     brouard  9270:   fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
1.145     brouard  9271:   /* fprintf(ficgp, "set size 0.65,0.65\n"); */
1.126     brouard  9272:   fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
                   9273: 
                   9274: } 
                   9275: 
1.136     brouard  9276: int readdata(char datafile[], int firstobs, int lastobs, int *imax)
                   9277: {
1.126     brouard  9278: 
1.136     brouard  9279:   /*-------- data file ----------*/
                   9280:   FILE *fic;
                   9281:   char dummy[]="                         ";
1.240     brouard  9282:   int i=0, j=0, n=0, iv=0, v;
1.223     brouard  9283:   int lstra;
1.136     brouard  9284:   int linei, month, year,iout;
1.302     brouard  9285:   int noffset=0; /* This is the offset if BOM data file */
1.136     brouard  9286:   char line[MAXLINE], linetmp[MAXLINE];
1.164     brouard  9287:   char stra[MAXLINE], strb[MAXLINE];
1.136     brouard  9288:   char *stratrunc;
1.223     brouard  9289: 
1.240     brouard  9290:   DummyV=ivector(1,NCOVMAX); /* 1 to 3 */
                   9291:   FixedV=ivector(1,NCOVMAX); /* 1 to 3 */
1.126     brouard  9292: 
1.240     brouard  9293:   for(v=1; v <=ncovcol;v++){
                   9294:     DummyV[v]=0;
                   9295:     FixedV[v]=0;
                   9296:   }
                   9297:   for(v=ncovcol+1; v <=ncovcol+nqv;v++){
                   9298:     DummyV[v]=1;
                   9299:     FixedV[v]=0;
                   9300:   }
                   9301:   for(v=ncovcol+nqv+1; v <=ncovcol+nqv+ntv;v++){
                   9302:     DummyV[v]=0;
                   9303:     FixedV[v]=1;
                   9304:   }
                   9305:   for(v=ncovcol+nqv+ntv+1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9306:     DummyV[v]=1;
                   9307:     FixedV[v]=1;
                   9308:   }
                   9309:   for(v=1; v <=ncovcol+nqv+ntv+nqtv;v++){
                   9310:     printf("Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9311:     fprintf(ficlog,"Covariate type in the data: V%d, DummyV(V%d)=%d, FixedV(V%d)=%d\n",v,v,DummyV[v],v,FixedV[v]);
                   9312:   }
1.126     brouard  9313: 
1.136     brouard  9314:   if((fic=fopen(datafile,"r"))==NULL)    {
1.218     brouard  9315:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9316:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
1.136     brouard  9317:   }
1.126     brouard  9318: 
1.302     brouard  9319:     /* Is it a BOM UTF-8 Windows file? */
                   9320:   /* First data line */
                   9321:   linei=0;
                   9322:   while(fgets(line, MAXLINE, fic)) {
                   9323:     noffset=0;
                   9324:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   9325:     {
                   9326:       noffset=noffset+3;
                   9327:       printf("# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);fflush(stdout);
                   9328:       fprintf(ficlog,"# Data file '%s'  is an UTF8 BOM file, please convert to UTF8 or ascii file and rerun.\n",datafile);
                   9329:       fflush(ficlog); return 1;
                   9330:     }
                   9331:     /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   9332:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
                   9333:     {
                   9334:       noffset=noffset+2;
1.304     brouard  9335:       printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9336:       fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9337:       fflush(ficlog); return 1;
                   9338:     }
                   9339:     else if( line[0] == 0 && line[1] == 0)
                   9340:     {
                   9341:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   9342:        noffset=noffset+4;
1.304     brouard  9343:        printf("# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);fflush(stdout);
                   9344:        fprintf(ficlog,"# Error Data file '%s'  is a huge UTF16BE BOM file, please convert to UTF8 or ascii file (for example with dos2unix) and rerun.\n",datafile);
1.302     brouard  9345:        fflush(ficlog); return 1;
                   9346:       }
                   9347:     } else{
                   9348:       ;/*printf(" Not a BOM file\n");*/
                   9349:     }
                   9350:         /* If line starts with a # it is a comment */
                   9351:     if (line[noffset] == '#') {
                   9352:       linei=linei+1;
                   9353:       break;
                   9354:     }else{
                   9355:       break;
                   9356:     }
                   9357:   }
                   9358:   fclose(fic);
                   9359:   if((fic=fopen(datafile,"r"))==NULL)    {
                   9360:     printf("Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(stdout);
                   9361:     fprintf(ficlog,"Problem while opening datafile: %s with errno='%s'\n", datafile,strerror(errno));fflush(ficlog);return 1;
                   9362:   }
                   9363:   /* Not a Bom file */
                   9364:   
1.136     brouard  9365:   i=1;
                   9366:   while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
                   9367:     linei=linei+1;
                   9368:     for(j=strlen(line); j>=0;j--){  /* Untabifies line */
                   9369:       if(line[j] == '\t')
                   9370:        line[j] = ' ';
                   9371:     }
                   9372:     for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
                   9373:       ;
                   9374:     };
                   9375:     line[j+1]=0;  /* Trims blanks at end of line */
                   9376:     if(line[0]=='#'){
                   9377:       fprintf(ficlog,"Comment line\n%s\n",line);
                   9378:       printf("Comment line\n%s\n",line);
                   9379:       continue;
                   9380:     }
                   9381:     trimbb(linetmp,line); /* Trims multiple blanks in line */
1.164     brouard  9382:     strcpy(line, linetmp);
1.223     brouard  9383:     
                   9384:     /* Loops on waves */
                   9385:     for (j=maxwav;j>=1;j--){
                   9386:       for (iv=nqtv;iv>=1;iv--){  /* Loop  on time varying quantitative variables */
1.238     brouard  9387:        cutv(stra, strb, line, ' '); 
                   9388:        if(strb[0]=='.') { /* Missing value */
                   9389:          lval=-1;
                   9390:          cotqvar[j][iv][i]=-1; /* 0.0/0.0 */
                   9391:          cotvar[j][ntv+iv][i]=-1; /* For performance reasons */
                   9392:          if(isalpha(strb[1])) { /* .m or .d Really Missing value */
                   9393:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);
                   9394:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. If missing, you should remove this individual or impute a value.  Exiting.\n", strb, linei,i,line,iv, nqtv, j);fflush(ficlog);
                   9395:            return 1;
                   9396:          }
                   9397:        }else{
                   9398:          errno=0;
                   9399:          /* what_kind_of_number(strb); */
                   9400:          dval=strtod(strb,&endptr); 
                   9401:          /* if( strb[0]=='\0' || (*endptr != '\0')){ */
                   9402:          /* if(strb != endptr && *endptr == '\0') */
                   9403:          /*    dval=dlval; */
                   9404:          /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9405:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9406:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, nqtv, j,maxwav);
                   9407:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqtv, j,maxwav);fflush(ficlog);
                   9408:            return 1;
                   9409:          }
                   9410:          cotqvar[j][iv][i]=dval; 
                   9411:          cotvar[j][ntv+iv][i]=dval; 
                   9412:        }
                   9413:        strcpy(line,stra);
1.223     brouard  9414:       }/* end loop ntqv */
1.225     brouard  9415:       
1.223     brouard  9416:       for (iv=ntv;iv>=1;iv--){  /* Loop  on time varying dummies */
1.238     brouard  9417:        cutv(stra, strb, line, ' '); 
                   9418:        if(strb[0]=='.') { /* Missing value */
                   9419:          lval=-1;
                   9420:        }else{
                   9421:          errno=0;
                   9422:          lval=strtol(strb,&endptr,10); 
                   9423:          /*    if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9424:          if( strb[0]=='\0' || (*endptr != '\0')){
                   9425:            printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th dummy covariate out of %d measured at wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv, j,maxwav);
                   9426:            fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d dummy covariate out of %d measured wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,iv, ntv,j,maxwav);fflush(ficlog);
                   9427:            return 1;
                   9428:          }
                   9429:        }
                   9430:        if(lval <-1 || lval >1){
                   9431:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9432:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9433:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9434:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9435:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9436:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9437:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9438:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9439:  Exiting.\n",lval,linei, i,line,j);
1.238     brouard  9440:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.223     brouard  9441:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9442:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.238     brouard  9443:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9444:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9445:         V1=1 V2=0 for (2) \n                                           \
1.223     brouard  9446:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.238     brouard  9447:  output of IMaCh is often meaningless.\n                               \
1.223     brouard  9448:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.238     brouard  9449:          return 1;
                   9450:        }
                   9451:        cotvar[j][iv][i]=(double)(lval);
                   9452:        strcpy(line,stra);
1.223     brouard  9453:       }/* end loop ntv */
1.225     brouard  9454:       
1.223     brouard  9455:       /* Statuses  at wave */
1.137     brouard  9456:       cutv(stra, strb, line, ' '); 
1.223     brouard  9457:       if(strb[0]=='.') { /* Missing value */
1.238     brouard  9458:        lval=-1;
1.136     brouard  9459:       }else{
1.238     brouard  9460:        errno=0;
                   9461:        lval=strtol(strb,&endptr,10); 
                   9462:        /*      if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
                   9463:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9464:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
                   9465:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
                   9466:          return 1;
                   9467:        }
1.136     brouard  9468:       }
1.225     brouard  9469:       
1.136     brouard  9470:       s[j][i]=lval;
1.225     brouard  9471:       
1.223     brouard  9472:       /* Date of Interview */
1.136     brouard  9473:       strcpy(line,stra);
                   9474:       cutv(stra, strb,line,' ');
1.169     brouard  9475:       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9476:       }
1.169     brouard  9477:       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.225     brouard  9478:        month=99;
                   9479:        year=9999;
1.136     brouard  9480:       }else{
1.225     brouard  9481:        printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
                   9482:        fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
                   9483:        return 1;
1.136     brouard  9484:       }
                   9485:       anint[j][i]= (double) year; 
1.302     brouard  9486:       mint[j][i]= (double)month;
                   9487:       /* if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){ */
                   9488:       /*       printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9489:       /*       fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, mint[j][i],anint[j][i], moisnais[i],annais[i]); */
                   9490:       /* } */
1.136     brouard  9491:       strcpy(line,stra);
1.223     brouard  9492:     } /* End loop on waves */
1.225     brouard  9493:     
1.223     brouard  9494:     /* Date of death */
1.136     brouard  9495:     cutv(stra, strb,line,' '); 
1.169     brouard  9496:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9497:     }
1.169     brouard  9498:     else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
1.136     brouard  9499:       month=99;
                   9500:       year=9999;
                   9501:     }else{
1.141     brouard  9502:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
1.225     brouard  9503:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
                   9504:       return 1;
1.136     brouard  9505:     }
                   9506:     andc[i]=(double) year; 
                   9507:     moisdc[i]=(double) month; 
                   9508:     strcpy(line,stra);
                   9509:     
1.223     brouard  9510:     /* Date of birth */
1.136     brouard  9511:     cutv(stra, strb,line,' '); 
1.169     brouard  9512:     if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
1.136     brouard  9513:     }
1.169     brouard  9514:     else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
1.136     brouard  9515:       month=99;
                   9516:       year=9999;
                   9517:     }else{
1.141     brouard  9518:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
                   9519:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9520:       return 1;
1.136     brouard  9521:     }
                   9522:     if (year==9999) {
1.141     brouard  9523:       printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
                   9524:       fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
1.225     brouard  9525:       return 1;
                   9526:       
1.136     brouard  9527:     }
                   9528:     annais[i]=(double)(year);
1.302     brouard  9529:     moisnais[i]=(double)(month);
                   9530:     for (j=1;j<=maxwav;j++){
                   9531:       if( (int)anint[j][i]+ (int)(mint[j][i])/12. < (int) (moisnais[i]/12.+annais[i])){
                   9532:        printf("Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j,(int)moisnais[i],(int)annais[i]);
                   9533:        fprintf(ficlog,"Warning reading data around '%s' at line number %d for individual %d, '%s'\nThe date of interview (%2d/%4d) at wave %d occurred before the date of birth (%2d/%4d).\n",strb, linei,i, line, (int)mint[j][i],(int)anint[j][i], j, (int)moisnais[i],(int)annais[i]);
                   9534:       }
                   9535:     }
                   9536: 
1.136     brouard  9537:     strcpy(line,stra);
1.225     brouard  9538:     
1.223     brouard  9539:     /* Sample weight */
1.136     brouard  9540:     cutv(stra, strb,line,' '); 
                   9541:     errno=0;
                   9542:     dval=strtod(strb,&endptr); 
                   9543:     if( strb[0]=='\0' || (*endptr != '\0')){
1.141     brouard  9544:       printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
                   9545:       fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
1.136     brouard  9546:       fflush(ficlog);
                   9547:       return 1;
                   9548:     }
                   9549:     weight[i]=dval; 
                   9550:     strcpy(line,stra);
1.225     brouard  9551:     
1.223     brouard  9552:     for (iv=nqv;iv>=1;iv--){  /* Loop  on fixed quantitative variables */
                   9553:       cutv(stra, strb, line, ' '); 
                   9554:       if(strb[0]=='.') { /* Missing value */
1.225     brouard  9555:        lval=-1;
1.311     brouard  9556:        coqvar[iv][i]=NAN; 
                   9557:        covar[ncovcol+iv][i]=NAN; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9558:       }else{
1.225     brouard  9559:        errno=0;
                   9560:        /* what_kind_of_number(strb); */
                   9561:        dval=strtod(strb,&endptr);
                   9562:        /* if(strb != endptr && *endptr == '\0') */
                   9563:        /*   dval=dlval; */
                   9564:        /* if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN)) */
                   9565:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9566:          printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);
                   9567:          fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be the %d th quantitative value (out of %d) constant for all waves. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line, iv, nqv, maxwav);fflush(ficlog);
                   9568:          return 1;
                   9569:        }
                   9570:        coqvar[iv][i]=dval; 
1.226     brouard  9571:        covar[ncovcol+iv][i]=dval; /* including qvar in standard covar for performance reasons */ 
1.223     brouard  9572:       }
                   9573:       strcpy(line,stra);
                   9574:     }/* end loop nqv */
1.136     brouard  9575:     
1.223     brouard  9576:     /* Covariate values */
1.136     brouard  9577:     for (j=ncovcol;j>=1;j--){
                   9578:       cutv(stra, strb,line,' '); 
1.223     brouard  9579:       if(strb[0]=='.') { /* Missing covariate value */
1.225     brouard  9580:        lval=-1;
1.136     brouard  9581:       }else{
1.225     brouard  9582:        errno=0;
                   9583:        lval=strtol(strb,&endptr,10); 
                   9584:        if( strb[0]=='\0' || (*endptr != '\0')){
                   9585:          printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
                   9586:          fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
                   9587:          return 1;
                   9588:        }
1.136     brouard  9589:       }
                   9590:       if(lval <-1 || lval >1){
1.225     brouard  9591:        printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9592:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9593:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9594:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9595:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9596:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9597:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9598:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9599:  Exiting.\n",lval,linei, i,line,j);
1.225     brouard  9600:        fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
1.136     brouard  9601:  Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
                   9602:  for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
1.225     brouard  9603:  For example, for multinomial values like 1, 2 and 3,\n                        \
                   9604:  build V1=0 V2=0 for the reference value (1),\n                                \
                   9605:         V1=1 V2=0 for (2) \n                                           \
1.136     brouard  9606:  and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
1.225     brouard  9607:  output of IMaCh is often meaningless.\n                               \
1.136     brouard  9608:  Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
1.225     brouard  9609:        return 1;
1.136     brouard  9610:       }
                   9611:       covar[j][i]=(double)(lval);
                   9612:       strcpy(line,stra);
                   9613:     }  
                   9614:     lstra=strlen(stra);
1.225     brouard  9615:     
1.136     brouard  9616:     if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
                   9617:       stratrunc = &(stra[lstra-9]);
                   9618:       num[i]=atol(stratrunc);
                   9619:     }
                   9620:     else
                   9621:       num[i]=atol(stra);
                   9622:     /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
                   9623:       printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
                   9624:     
                   9625:     i=i+1;
                   9626:   } /* End loop reading  data */
1.225     brouard  9627:   
1.136     brouard  9628:   *imax=i-1; /* Number of individuals */
                   9629:   fclose(fic);
1.225     brouard  9630:   
1.136     brouard  9631:   return (0);
1.164     brouard  9632:   /* endread: */
1.225     brouard  9633:   printf("Exiting readdata: ");
                   9634:   fclose(fic);
                   9635:   return (1);
1.223     brouard  9636: }
1.126     brouard  9637: 
1.234     brouard  9638: void removefirstspace(char **stri){/*, char stro[]) {*/
1.230     brouard  9639:   char *p1 = *stri, *p2 = *stri;
1.235     brouard  9640:   while (*p2 == ' ')
1.234     brouard  9641:     p2++; 
                   9642:   /* while ((*p1++ = *p2++) !=0) */
                   9643:   /*   ; */
                   9644:   /* do */
                   9645:   /*   while (*p2 == ' ') */
                   9646:   /*     p2++; */
                   9647:   /* while (*p1++ == *p2++); */
                   9648:   *stri=p2; 
1.145     brouard  9649: }
                   9650: 
1.235     brouard  9651: int decoderesult ( char resultline[], int nres)
1.230     brouard  9652: /**< This routine decode one result line and returns the combination # of dummy covariates only **/
                   9653: {
1.235     brouard  9654:   int j=0, k=0, k1=0, k2=0, k3=0, k4=0, match=0, k2q=0, k3q=0, k4q=0;
1.230     brouard  9655:   char resultsav[MAXLINE];
1.234     brouard  9656:   int resultmodel[MAXLINE];
                   9657:   int modelresult[MAXLINE];
1.230     brouard  9658:   char stra[80], strb[80], strc[80], strd[80],stre[80];
                   9659: 
1.234     brouard  9660:   removefirstspace(&resultline);
1.230     brouard  9661: 
                   9662:   if (strstr(resultline,"v") !=0){
                   9663:     printf("Error. 'v' must be in upper case 'V' result: %s ",resultline);
                   9664:     fprintf(ficlog,"Error. 'v' must be in upper case result: %s ",resultline);fflush(ficlog);
                   9665:     return 1;
                   9666:   }
                   9667:   trimbb(resultsav, resultline);
                   9668:   if (strlen(resultsav) >1){
                   9669:     j=nbocc(resultsav,'='); /**< j=Number of covariate values'=' */
                   9670:   }
1.253     brouard  9671:   if(j == 0){ /* Resultline but no = */
                   9672:     TKresult[nres]=0; /* Combination for the nresult and the model */
                   9673:     return (0);
                   9674:   }
1.234     brouard  9675:   if( j != cptcovs ){ /* Be careful if a variable is in a product but not single */
1.310     brouard  9676:     printf("ERROR: the number of variables in the resultline, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
                   9677:     fprintf(ficlog,"ERROR: the number of variables in the resultline, %d, differs from the number of variables used in the model line, %d.\n",j, cptcovs);
1.234     brouard  9678:   }
                   9679:   for(k=1; k<=j;k++){ /* Loop on any covariate of the result line */
                   9680:     if(nbocc(resultsav,'=') >1){
                   9681:        cutl(stra,strb,resultsav,' '); /* keeps in strb after the first ' ' 
1.310     brouard  9682:                                      resultsav= V4=1 V5=25.1 V3=0 stra= V5=25.1 V3=0 strb= V4=1 */
1.234     brouard  9683:        cutl(strc,strd,strb,'=');  /* strb:V4=1 strc=1 strd=V4 */
                   9684:     }else
                   9685:       cutl(strc,strd,resultsav,'=');
1.230     brouard  9686:     Tvalsel[k]=atof(strc); /* 1 */
1.234     brouard  9687:     
1.230     brouard  9688:     cutl(strc,stre,strd,'V'); /* strd='V4' strc=4 stre='V' */;
                   9689:     Tvarsel[k]=atoi(strc);
                   9690:     /* Typevarsel[k]=1;  /\* 1 for age product *\/ */
                   9691:     /* cptcovsel++;     */
                   9692:     if (nbocc(stra,'=') >0)
                   9693:       strcpy(resultsav,stra); /* and analyzes it */
                   9694:   }
1.235     brouard  9695:   /* Checking for missing or useless values in comparison of current model needs */
1.236     brouard  9696:   for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9697:     if(Typevar[k1]==0){ /* Single covariate in model */
1.234     brouard  9698:       match=0;
1.236     brouard  9699:       for(k2=1; k2 <=j;k2++){/* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.237     brouard  9700:        if(Tvar[k1]==Tvarsel[k2]) {/* Tvar[1]=5 == Tvarsel[2]=5   */
1.236     brouard  9701:          modelresult[k2]=k1;/* modelresult[2]=1 modelresult[1]=2  modelresult[3]=3  modelresult[6]=4 modelresult[9]=5 */
1.234     brouard  9702:          match=1;
                   9703:          break;
                   9704:        }
                   9705:       }
                   9706:       if(match == 0){
1.310     brouard  9707:        printf("Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9708:        fprintf(ficlog,"Error in result line: V%d is missing in result: %s according to model=%s\n",k1, resultline, model);
                   9709:        return 1;
1.234     brouard  9710:       }
                   9711:     }
                   9712:   }
1.235     brouard  9713:   /* Checking for missing or useless values in comparison of current model needs */
                   9714:   for(k2=1; k2 <=j;k2++){ /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
1.234     brouard  9715:     match=0;
1.235     brouard  9716:     for(k1=1; k1<= cptcovt ;k1++){ /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9717:       if(Typevar[k1]==0){ /* Single */
1.237     brouard  9718:        if(Tvar[k1]==Tvarsel[k2]) { /* Tvar[2]=4 == Tvarsel[1]=4   */
1.235     brouard  9719:          resultmodel[k1]=k2;  /* resultmodel[2]=1 resultmodel[1]=2  resultmodel[3]=3  resultmodel[6]=4 resultmodel[9]=5 */
1.234     brouard  9720:          ++match;
                   9721:        }
                   9722:       }
                   9723:     }
                   9724:     if(match == 0){
                   9725:       printf("Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
1.310     brouard  9726:       fprintf(ficlog,"Error in result line: %d value missing; result: %s, model=%s\n",k1, resultline, model);
                   9727:       return 1;
1.234     brouard  9728:     }else if(match > 1){
                   9729:       printf("Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
1.310     brouard  9730:       fprintf(ficlog,"Error in result line: %d doubled; result: %s, model=%s\n",k2, resultline, model);
                   9731:       return 1;
1.234     brouard  9732:     }
                   9733:   }
1.235     brouard  9734:       
1.234     brouard  9735:   /* We need to deduce which combination number is chosen and save quantitative values */
1.235     brouard  9736:   /* model line V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   9737:   /* result line V4=1 V5=25.1 V3=0  V2=8 V1=1 */
                   9738:   /* should give a combination of dummy V4=1, V3=0, V1=1 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 5 + (1offset) = 6*/
                   9739:   /* result line V4=1 V5=24.1 V3=1  V2=8 V1=0 */
                   9740:   /* should give a combination of dummy V4=1, V3=1, V1=0 => V4*2**(0) + V3*2**(1) + V1*2**(2) = 3 + (1offset) = 4*/
                   9741:   /*    1 0 0 0 */
                   9742:   /*    2 1 0 0 */
                   9743:   /*    3 0 1 0 */ 
                   9744:   /*    4 1 1 0 */ /* V4=1, V3=1, V1=0 */
                   9745:   /*    5 0 0 1 */
                   9746:   /*    6 1 0 1 */ /* V4=1, V3=0, V1=1 */
                   9747:   /*    7 0 1 1 */
                   9748:   /*    8 1 1 1 */
1.237     brouard  9749:   /* V(Tvresult)=Tresult V4=1 V3=0 V1=1 Tresult[nres=1][2]=0 */
                   9750:   /* V(Tvqresult)=Tqresult V5=25.1 V2=8 Tqresult[nres=1][1]=25.1 */
                   9751:   /* V5*age V5 known which value for nres?  */
                   9752:   /* Tqinvresult[2]=8 Tqinvresult[1]=25.1  */
1.235     brouard  9753:   for(k1=1, k=0, k4=0, k4q=0; k1 <=cptcovt;k1++){ /* model line */
                   9754:     if( Dummy[k1]==0 && Typevar[k1]==0 ){ /* Single dummy */
1.237     brouard  9755:       k3= resultmodel[k1]; /* resultmodel[2(V4)] = 1=k3 */
1.235     brouard  9756:       k2=(int)Tvarsel[k3]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
                   9757:       k+=Tvalsel[k3]*pow(2,k4);  /*  Tvalsel[1]=1  */
1.237     brouard  9758:       Tresult[nres][k4+1]=Tvalsel[k3];/* Tresult[nres][1]=1(V4=1)  Tresult[nres][2]=0(V3=0) */
                   9759:       Tvresult[nres][k4+1]=(int)Tvarsel[k3];/* Tvresult[nres][1]=4 Tvresult[nres][3]=1 */
                   9760:       Tinvresult[nres][(int)Tvarsel[k3]]=Tvalsel[k3]; /* Tinvresult[nres][4]=1 */
1.235     brouard  9761:       printf("Decoderesult Dummy k=%d, V(k2=V%d)= Tvalsel[%d]=%d, 2**(%d)\n",k, k2, k3, (int)Tvalsel[k3], k4);
                   9762:       k4++;;
                   9763:     }  else if( Dummy[k1]==1 && Typevar[k1]==0 ){ /* Single quantitative */
                   9764:       k3q= resultmodel[k1]; /* resultmodel[2] = 1=k3 */
                   9765:       k2q=(int)Tvarsel[k3q]; /*  Tvarsel[resultmodel[2]]= Tvarsel[1] = 4=k2 */
1.237     brouard  9766:       Tqresult[nres][k4q+1]=Tvalsel[k3q]; /* Tqresult[nres][1]=25.1 */
                   9767:       Tvqresult[nres][k4q+1]=(int)Tvarsel[k3q]; /* Tvqresult[nres][1]=5 */
                   9768:       Tqinvresult[nres][(int)Tvarsel[k3q]]=Tvalsel[k3q]; /* Tqinvresult[nres][5]=25.1 */
1.235     brouard  9769:       printf("Decoderesult Quantitative nres=%d, V(k2q=V%d)= Tvalsel[%d]=%d, Tvarsel[%d]=%f\n",nres, k2q, k3q, Tvarsel[k3q], k3q, Tvalsel[k3q]);
                   9770:       k4q++;;
                   9771:     }
                   9772:   }
1.234     brouard  9773:   
1.235     brouard  9774:   TKresult[nres]=++k; /* Combination for the nresult and the model */
1.230     brouard  9775:   return (0);
                   9776: }
1.235     brouard  9777: 
1.230     brouard  9778: int decodemodel( char model[], int lastobs)
                   9779:  /**< This routine decodes the model and returns:
1.224     brouard  9780:        * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
                   9781:        * - nagesqr = 1 if age*age in the model, otherwise 0.
                   9782:        * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
                   9783:        * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
                   9784:        * - cptcovage number of covariates with age*products =2
                   9785:        * - cptcovs number of simple covariates
                   9786:        * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
                   9787:        *     which is a new column after the 9 (ncovcol) variables. 
                   9788:        * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
                   9789:        * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
                   9790:        *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
                   9791:        * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
                   9792:        */
1.136     brouard  9793: {
1.238     brouard  9794:   int i, j, k, ks, v;
1.227     brouard  9795:   int  j1, k1, k2, k3, k4;
1.136     brouard  9796:   char modelsav[80];
1.145     brouard  9797:   char stra[80], strb[80], strc[80], strd[80],stre[80];
1.187     brouard  9798:   char *strpt;
1.136     brouard  9799: 
1.145     brouard  9800:   /*removespace(model);*/
1.136     brouard  9801:   if (strlen(model) >1){ /* If there is at least 1 covariate */
1.145     brouard  9802:     j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
1.137     brouard  9803:     if (strstr(model,"AGE") !=0){
1.192     brouard  9804:       printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
                   9805:       fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
1.136     brouard  9806:       return 1;
                   9807:     }
1.141     brouard  9808:     if (strstr(model,"v") !=0){
                   9809:       printf("Error. 'v' must be in upper case 'V' model=%s ",model);
                   9810:       fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
                   9811:       return 1;
                   9812:     }
1.187     brouard  9813:     strcpy(modelsav,model); 
                   9814:     if ((strpt=strstr(model,"age*age")) !=0){
                   9815:       printf(" strpt=%s, model=%s\n",strpt, model);
                   9816:       if(strpt != model){
1.234     brouard  9817:        printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9818:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9819:  corresponding column of parameters.\n",model);
1.234     brouard  9820:        fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
1.192     brouard  9821:  'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
1.187     brouard  9822:  corresponding column of parameters.\n",model); fflush(ficlog);
1.234     brouard  9823:        return 1;
1.225     brouard  9824:       }
1.187     brouard  9825:       nagesqr=1;
                   9826:       if (strstr(model,"+age*age") !=0)
1.234     brouard  9827:        substrchaine(modelsav, model, "+age*age");
1.187     brouard  9828:       else if (strstr(model,"age*age+") !=0)
1.234     brouard  9829:        substrchaine(modelsav, model, "age*age+");
1.187     brouard  9830:       else 
1.234     brouard  9831:        substrchaine(modelsav, model, "age*age");
1.187     brouard  9832:     }else
                   9833:       nagesqr=0;
                   9834:     if (strlen(modelsav) >1){
                   9835:       j=nbocc(modelsav,'+'); /**< j=Number of '+' */
                   9836:       j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
1.224     brouard  9837:       cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =5-3=2  */
1.187     brouard  9838:       cptcovt= j+1; /* Number of total covariates in the model, not including
1.225     brouard  9839:                     * cst, age and age*age 
                   9840:                     * V1+V1*age+ V3 + V3*V4+age*age=> 3+1=4*/
                   9841:       /* including age products which are counted in cptcovage.
                   9842:        * but the covariates which are products must be treated 
                   9843:        * separately: ncovn=4- 2=2 (V1+V3). */
1.187     brouard  9844:       cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
                   9845:       cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
1.225     brouard  9846:       
                   9847:       
1.187     brouard  9848:       /*   Design
                   9849:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
                   9850:        *  <          ncovcol=8                >
                   9851:        * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
                   9852:        *   k=  1    2      3       4     5       6      7        8
                   9853:        *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
                   9854:        *  covar[k,i], value of kth covariate if not including age for individual i:
1.224     brouard  9855:        *       covar[1][i]= (V1), covar[4][i]=(V4), covar[8][i]=(V8)
                   9856:        *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[2]=1 Tvar[4]=3 Tvar[8]=8
1.187     brouard  9857:        *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
                   9858:        *  Tage[++cptcovage]=k
                   9859:        *       if products, new covar are created after ncovcol with k1
                   9860:        *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
                   9861:        *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
                   9862:        *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
                   9863:        *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
                   9864:        *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
                   9865:        *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
                   9866:        *  <          ncovcol=8                >
                   9867:        *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
                   9868:        *          k=  1    2      3       4     5       6      7        8    9   10   11  12
                   9869:        *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
                   9870:        * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9871:        * p Tprod[1]@2={                         6, 5}
                   9872:        *p Tvard[1][1]@4= {7, 8, 5, 6}
                   9873:        * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
                   9874:        *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
                   9875:        *How to reorganize?
                   9876:        * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
                   9877:        * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
                   9878:        *       {2,   1,     4,      8,    5,      6,     3,       7}
                   9879:        * Struct []
                   9880:        */
1.225     brouard  9881:       
1.187     brouard  9882:       /* This loop fills the array Tvar from the string 'model'.*/
                   9883:       /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
                   9884:       /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
                   9885:       /*       k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
                   9886:       /*       k=3 V4 Tvar[k=3]= 4 (from V4) */
                   9887:       /*       k=2 V1 Tvar[k=2]= 1 (from V1) */
                   9888:       /*       k=1 Tvar[1]=2 (from V2) */
                   9889:       /*       k=5 Tvar[5] */
                   9890:       /* for (k=1; k<=cptcovn;k++) { */
1.198     brouard  9891:       /*       cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
1.187     brouard  9892:       /*       } */
1.198     brouard  9893:       /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
1.187     brouard  9894:       /*
                   9895:        * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
1.227     brouard  9896:       for(k=cptcovt; k>=1;k--){ /**< Number of covariates not including constant and age, neither age*age*/
                   9897:         Tvar[k]=0; Tprod[k]=0; Tposprod[k]=0;
                   9898:       }
1.187     brouard  9899:       cptcovage=0;
                   9900:       for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
1.234     brouard  9901:        cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
1.225     brouard  9902:                                         modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
1.234     brouard  9903:        if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
                   9904:        /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
                   9905:        /*scanf("%d",i);*/
                   9906:        if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
                   9907:          cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
                   9908:          if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
                   9909:            /* covar is not filled and then is empty */
                   9910:            cptcovprod--;
                   9911:            cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
                   9912:            Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
                   9913:            Typevar[k]=1;  /* 1 for age product */
                   9914:            cptcovage++; /* Sums the number of covariates which include age as a product */
                   9915:            Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
                   9916:            /*printf("stre=%s ", stre);*/
                   9917:          } else if (strcmp(strd,"age")==0) { /* or age*Vn */
                   9918:            cptcovprod--;
                   9919:            cutl(stre,strb,strc,'V');
                   9920:            Tvar[k]=atoi(stre);
                   9921:            Typevar[k]=1;  /* 1 for age product */
                   9922:            cptcovage++;
                   9923:            Tage[cptcovage]=k;
                   9924:          } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
                   9925:            /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
                   9926:            cptcovn++;
                   9927:            cptcovprodnoage++;k1++;
                   9928:            cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
                   9929:            Tvar[k]=ncovcol+nqv+ntv+nqtv+k1; /* For model-covariate k tells which data-covariate to use but
                   9930:                                                because this model-covariate is a construction we invent a new column
                   9931:                                                which is after existing variables ncovcol+nqv+ntv+nqtv + k1
                   9932:                                                If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                   9933:                                                Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
                   9934:            Typevar[k]=2;  /* 2 for double fixed dummy covariates */
                   9935:            cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
                   9936:            Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
                   9937:            Tposprod[k]=k1; /* Tpsprod[3]=1, Tposprod[2]=5 */
                   9938:            Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
                   9939:            Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
                   9940:            k2=k2+2;  /* k2 is initialize to -1, We want to store the n and m in Vn*Vm at the end of Tvar */
                   9941:            /* Tvar[cptcovt+k2]=Tvard[k1][1]; /\* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) *\/ */
                   9942:            /* Tvar[cptcovt+k2+1]=Tvard[k1][2];  /\* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) *\/ */
1.225     brouard  9943:             /*ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2, Tvar[3]=5, Tvar[4]=6, cptcovt=5 */
1.234     brouard  9944:            /*                     1  2   3      4     5 | Tvar[5+1)=1, Tvar[7]=2   */
                   9945:            for (i=1; i<=lastobs;i++){
                   9946:              /* Computes the new covariate which is a product of
                   9947:                 covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                   9948:              covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
                   9949:            }
                   9950:          } /* End age is not in the model */
                   9951:        } /* End if model includes a product */
                   9952:        else { /* no more sum */
                   9953:          /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
                   9954:          /*  scanf("%d",i);*/
                   9955:          cutl(strd,strc,strb,'V');
                   9956:          ks++; /**< Number of simple covariates dummy or quantitative, fixe or varying */
                   9957:          cptcovn++; /** V4+V3+V5: V4 and V3 timevarying dummy covariates, V5 timevarying quantitative */
                   9958:          Tvar[k]=atoi(strd);
                   9959:          Typevar[k]=0;  /* 0 for simple covariates */
                   9960:        }
                   9961:        strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
1.223     brouard  9962:                                /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
1.225     brouard  9963:                                  scanf("%d",i);*/
1.187     brouard  9964:       } /* end of loop + on total covariates */
                   9965:     } /* end if strlen(modelsave == 0) age*age might exist */
                   9966:   } /* end if strlen(model == 0) */
1.136     brouard  9967:   
                   9968:   /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
                   9969:     If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
1.225     brouard  9970:   
1.136     brouard  9971:   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
1.225     brouard  9972:      printf("cptcovprod=%d ", cptcovprod);
                   9973:      fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
                   9974:      scanf("%d ",i);*/
                   9975: 
                   9976: 
1.230     brouard  9977: /* Until here, decodemodel knows only the grammar (simple, product, age*) of the model but not what kind
                   9978:    of variable (dummy vs quantitative, fixed vs time varying) is behind. But we know the # of each. */
1.226     brouard  9979: /* ncovcol= 1, nqv=1 | ntv=2, nqtv= 1  = 5 possible variables data: 2 fixed 3, varying
                   9980:    model=        V5 + V4 +V3 + V4*V3 + V5*age + V2 + V1*V2 + V1*age + V5*age, V1 is not used saving its place
                   9981:    k =           1    2   3     4       5       6      7      8        9
                   9982:    Tvar[k]=      5    4   3 1+1+2+1+1=6 5       2      7      1        5
                   9983:    Typevar[k]=   0    0   0     2       1       0      2      1        1
1.227     brouard  9984:    Fixed[k]      1    1   1     1       3       0    0 or 2   2        3
                   9985:    Dummy[k]      1    0   0     0       3       1      1      2        3
                   9986:          Tmodelind[combination of covar]=k;
1.225     brouard  9987: */  
                   9988: /* Dispatching between quantitative and time varying covariates */
1.226     brouard  9989:   /* If Tvar[k] >ncovcol it is a product */
1.225     brouard  9990:   /* Tvar[k] is the value n of Vn with n varying for 1 to nvcol, or p  Vp=Vn*Vm for product */
1.226     brouard  9991:        /* Computing effective variables, ie used by the model, that is from the cptcovt variables */
1.227     brouard  9992:   printf("Model=%s\n\
                   9993: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9994: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9995: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
                   9996:   fprintf(ficlog,"Model=%s\n\
                   9997: Typevar: 0 for simple covariate (dummy, quantitative, fixed or varying), 1 for age product, 2 for  product \n\
                   9998: Fixed[k] 0=fixed (product or simple), 1 varying, 2 fixed with age product, 3 varying with age product \n\
                   9999: Dummy[k] 0=dummy (0 1), 1 quantitative (single or product without age), 2 dummy with age product, 3 quant with age product\n",model);
1.285     brouard  10000:   for(k=-1;k<=cptcovt; k++){ Fixed[k]=0; Dummy[k]=0;}
1.234     brouard  10001:   for(k=1, ncovf=0, nsd=0, nsq=0, ncovv=0, ncova=0, ncoveff=0, nqfveff=0, ntveff=0, nqtveff=0;k<=cptcovt; k++){ /* or cptocvt */
                   10002:     if (Tvar[k] <=ncovcol && Typevar[k]==0 ){ /* Simple fixed dummy (<=ncovcol) covariates */
1.227     brouard  10003:       Fixed[k]= 0;
                   10004:       Dummy[k]= 0;
1.225     brouard  10005:       ncoveff++;
1.232     brouard  10006:       ncovf++;
1.234     brouard  10007:       nsd++;
                   10008:       modell[k].maintype= FTYPE;
                   10009:       TvarsD[nsd]=Tvar[k];
                   10010:       TvarsDind[nsd]=k;
                   10011:       TvarF[ncovf]=Tvar[k];
                   10012:       TvarFind[ncovf]=k;
                   10013:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10014:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
                   10015:     }else if( Tvar[k] <=ncovcol &&  Typevar[k]==2){ /* Product of fixed dummy (<=ncovcol) covariates */
                   10016:       Fixed[k]= 0;
                   10017:       Dummy[k]= 0;
                   10018:       ncoveff++;
                   10019:       ncovf++;
                   10020:       modell[k].maintype= FTYPE;
                   10021:       TvarF[ncovf]=Tvar[k];
                   10022:       TvarFind[ncovf]=k;
1.230     brouard  10023:       TvarFD[ncoveff]=Tvar[k]; /* TvarFD[1]=V1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.231     brouard  10024:       TvarFDind[ncoveff]=k; /* TvarFDind[1]=9 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */
1.240     brouard  10025:     }else if( Tvar[k] <=ncovcol+nqv && Typevar[k]==0){/* Remind that product Vn*Vm are added in k Only simple fixed quantitative variable */
1.227     brouard  10026:       Fixed[k]= 0;
                   10027:       Dummy[k]= 1;
1.230     brouard  10028:       nqfveff++;
1.234     brouard  10029:       modell[k].maintype= FTYPE;
                   10030:       modell[k].subtype= FQ;
                   10031:       nsq++;
                   10032:       TvarsQ[nsq]=Tvar[k];
                   10033:       TvarsQind[nsq]=k;
1.232     brouard  10034:       ncovf++;
1.234     brouard  10035:       TvarF[ncovf]=Tvar[k];
                   10036:       TvarFind[ncovf]=k;
1.231     brouard  10037:       TvarFQ[nqfveff]=Tvar[k]-ncovcol; /* TvarFQ[1]=V2-1=1st in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.230     brouard  10038:       TvarFQind[nqfveff]=k; /* TvarFQind[1]=6 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple fixed quantitative variable */
1.242     brouard  10039:     }else if( Tvar[k] <=ncovcol+nqv+ntv && Typevar[k]==0){/* Only simple time varying dummy variables */
1.227     brouard  10040:       Fixed[k]= 1;
                   10041:       Dummy[k]= 0;
1.225     brouard  10042:       ntveff++; /* Only simple time varying dummy variable */
1.234     brouard  10043:       modell[k].maintype= VTYPE;
                   10044:       modell[k].subtype= VD;
                   10045:       nsd++;
                   10046:       TvarsD[nsd]=Tvar[k];
                   10047:       TvarsDind[nsd]=k;
                   10048:       ncovv++; /* Only simple time varying variables */
                   10049:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10050:       TvarVind[ncovv]=k; /* TvarVind[2]=2  TvarVind[3]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10051:       TvarVD[ntveff]=Tvar[k]; /* TvarVD[1]=V4  TvarVD[2]=V3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
                   10052:       TvarVDind[ntveff]=k; /* TvarVDind[1]=2 TvarVDind[2]=3 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying dummy variable */
1.228     brouard  10053:       printf("Quasi Tmodelind[%d]=%d,Tvar[Tmodelind[%d]]=V%d, ncovcol=%d, nqv=%d,Tvar[k]- ncovcol-nqv=%d\n",ntveff,k,ntveff,Tvar[k], ncovcol, nqv,Tvar[k]- ncovcol-nqv);
                   10054:       printf("Quasi TmodelInvind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv);
1.231     brouard  10055:     }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv  && Typevar[k]==0){ /* Only simple time varying quantitative variable V5*/
1.234     brouard  10056:       Fixed[k]= 1;
                   10057:       Dummy[k]= 1;
                   10058:       nqtveff++;
                   10059:       modell[k].maintype= VTYPE;
                   10060:       modell[k].subtype= VQ;
                   10061:       ncovv++; /* Only simple time varying variables */
                   10062:       nsq++;
                   10063:       TvarsQ[nsq]=Tvar[k];
                   10064:       TvarsQind[nsq]=k;
                   10065:       TvarV[ncovv]=Tvar[k];
1.242     brouard  10066:       TvarVind[ncovv]=k; /* TvarVind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Any time varying singele */
1.231     brouard  10067:       TvarVQ[nqtveff]=Tvar[k]; /* TvarVQ[1]=V5 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
                   10068:       TvarVQind[nqtveff]=k; /* TvarVQind[1]=1 in V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 */ /* Only simple time varying quantitative variable */
1.234     brouard  10069:       TmodelInvQind[nqtveff]=Tvar[k]- ncovcol-nqv-ntv;/* Only simple time varying quantitative variable */
                   10070:       /* Tmodeliqind[k]=nqtveff;/\* Only simple time varying quantitative variable *\/ */
                   10071:       printf("Quasi TmodelQind[%d]=%d,Tvar[TmodelQind[%d]]=V%d, ncovcol=%d, nqv=%d, ntv=%d,Tvar[k]- ncovcol-nqv-ntv=%d\n",nqtveff,k,nqtveff,Tvar[k], ncovcol, nqv, ntv, Tvar[k]- ncovcol-nqv-ntv);
1.228     brouard  10072:       printf("Quasi TmodelInvQind[%d]=%d\n",k,Tvar[k]- ncovcol-nqv-ntv);
1.227     brouard  10073:     }else if (Typevar[k] == 1) {  /* product with age */
1.234     brouard  10074:       ncova++;
                   10075:       TvarA[ncova]=Tvar[k];
                   10076:       TvarAind[ncova]=k;
1.231     brouard  10077:       if (Tvar[k] <=ncovcol ){ /* Product age with fixed dummy covariatee */
1.240     brouard  10078:        Fixed[k]= 2;
                   10079:        Dummy[k]= 2;
                   10080:        modell[k].maintype= ATYPE;
                   10081:        modell[k].subtype= APFD;
                   10082:        /* ncoveff++; */
1.227     brouard  10083:       }else if( Tvar[k] <=ncovcol+nqv) { /* Remind that product Vn*Vm are added in k*/
1.240     brouard  10084:        Fixed[k]= 2;
                   10085:        Dummy[k]= 3;
                   10086:        modell[k].maintype= ATYPE;
                   10087:        modell[k].subtype= APFQ;                /*      Product age * fixed quantitative */
                   10088:        /* nqfveff++;  /\* Only simple fixed quantitative variable *\/ */
1.227     brouard  10089:       }else if( Tvar[k] <=ncovcol+nqv+ntv ){
1.240     brouard  10090:        Fixed[k]= 3;
                   10091:        Dummy[k]= 2;
                   10092:        modell[k].maintype= ATYPE;
                   10093:        modell[k].subtype= APVD;                /*      Product age * varying dummy */
                   10094:        /* ntveff++; /\* Only simple time varying dummy variable *\/ */
1.227     brouard  10095:       }else if( Tvar[k] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10096:        Fixed[k]= 3;
                   10097:        Dummy[k]= 3;
                   10098:        modell[k].maintype= ATYPE;
                   10099:        modell[k].subtype= APVQ;                /*      Product age * varying quantitative */
                   10100:        /* nqtveff++;/\* Only simple time varying quantitative variable *\/ */
1.227     brouard  10101:       }
                   10102:     }else if (Typevar[k] == 2) {  /* product without age */
                   10103:       k1=Tposprod[k];
                   10104:       if(Tvard[k1][1] <=ncovcol){
1.240     brouard  10105:        if(Tvard[k1][2] <=ncovcol){
                   10106:          Fixed[k]= 1;
                   10107:          Dummy[k]= 0;
                   10108:          modell[k].maintype= FTYPE;
                   10109:          modell[k].subtype= FPDD;              /*      Product fixed dummy * fixed dummy */
                   10110:          ncovf++; /* Fixed variables without age */
                   10111:          TvarF[ncovf]=Tvar[k];
                   10112:          TvarFind[ncovf]=k;
                   10113:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10114:          Fixed[k]= 0;  /* or 2 ?*/
                   10115:          Dummy[k]= 1;
                   10116:          modell[k].maintype= FTYPE;
                   10117:          modell[k].subtype= FPDQ;              /*      Product fixed dummy * fixed quantitative */
                   10118:          ncovf++; /* Varying variables without age */
                   10119:          TvarF[ncovf]=Tvar[k];
                   10120:          TvarFind[ncovf]=k;
                   10121:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10122:          Fixed[k]= 1;
                   10123:          Dummy[k]= 0;
                   10124:          modell[k].maintype= VTYPE;
                   10125:          modell[k].subtype= VPDD;              /*      Product fixed dummy * varying dummy */
                   10126:          ncovv++; /* Varying variables without age */
                   10127:          TvarV[ncovv]=Tvar[k];
                   10128:          TvarVind[ncovv]=k;
                   10129:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10130:          Fixed[k]= 1;
                   10131:          Dummy[k]= 1;
                   10132:          modell[k].maintype= VTYPE;
                   10133:          modell[k].subtype= VPDQ;              /*      Product fixed dummy * varying quantitative */
                   10134:          ncovv++; /* Varying variables without age */
                   10135:          TvarV[ncovv]=Tvar[k];
                   10136:          TvarVind[ncovv]=k;
                   10137:        }
1.227     brouard  10138:       }else if(Tvard[k1][1] <=ncovcol+nqv){
1.240     brouard  10139:        if(Tvard[k1][2] <=ncovcol){
                   10140:          Fixed[k]= 0;  /* or 2 ?*/
                   10141:          Dummy[k]= 1;
                   10142:          modell[k].maintype= FTYPE;
                   10143:          modell[k].subtype= FPDQ;              /*      Product fixed quantitative * fixed dummy */
                   10144:          ncovf++; /* Fixed variables without age */
                   10145:          TvarF[ncovf]=Tvar[k];
                   10146:          TvarFind[ncovf]=k;
                   10147:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10148:          Fixed[k]= 1;
                   10149:          Dummy[k]= 1;
                   10150:          modell[k].maintype= VTYPE;
                   10151:          modell[k].subtype= VPDQ;              /*      Product fixed quantitative * varying dummy */
                   10152:          ncovv++; /* Varying variables without age */
                   10153:          TvarV[ncovv]=Tvar[k];
                   10154:          TvarVind[ncovv]=k;
                   10155:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10156:          Fixed[k]= 1;
                   10157:          Dummy[k]= 1;
                   10158:          modell[k].maintype= VTYPE;
                   10159:          modell[k].subtype= VPQQ;              /*      Product fixed quantitative * varying quantitative */
                   10160:          ncovv++; /* Varying variables without age */
                   10161:          TvarV[ncovv]=Tvar[k];
                   10162:          TvarVind[ncovv]=k;
                   10163:          ncovv++; /* Varying variables without age */
                   10164:          TvarV[ncovv]=Tvar[k];
                   10165:          TvarVind[ncovv]=k;
                   10166:        }
1.227     brouard  10167:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv){
1.240     brouard  10168:        if(Tvard[k1][2] <=ncovcol){
                   10169:          Fixed[k]= 1;
                   10170:          Dummy[k]= 1;
                   10171:          modell[k].maintype= VTYPE;
                   10172:          modell[k].subtype= VPDD;              /*      Product time varying dummy * fixed dummy */
                   10173:          ncovv++; /* Varying variables without age */
                   10174:          TvarV[ncovv]=Tvar[k];
                   10175:          TvarVind[ncovv]=k;
                   10176:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10177:          Fixed[k]= 1;
                   10178:          Dummy[k]= 1;
                   10179:          modell[k].maintype= VTYPE;
                   10180:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * fixed quantitative */
                   10181:          ncovv++; /* Varying variables without age */
                   10182:          TvarV[ncovv]=Tvar[k];
                   10183:          TvarVind[ncovv]=k;
                   10184:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10185:          Fixed[k]= 1;
                   10186:          Dummy[k]= 0;
                   10187:          modell[k].maintype= VTYPE;
                   10188:          modell[k].subtype= VPDD;              /*      Product time varying dummy * time varying dummy */
                   10189:          ncovv++; /* Varying variables without age */
                   10190:          TvarV[ncovv]=Tvar[k];
                   10191:          TvarVind[ncovv]=k;
                   10192:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10193:          Fixed[k]= 1;
                   10194:          Dummy[k]= 1;
                   10195:          modell[k].maintype= VTYPE;
                   10196:          modell[k].subtype= VPDQ;              /*      Product time varying dummy * time varying quantitative */
                   10197:          ncovv++; /* Varying variables without age */
                   10198:          TvarV[ncovv]=Tvar[k];
                   10199:          TvarVind[ncovv]=k;
                   10200:        }
1.227     brouard  10201:       }else if(Tvard[k1][1] <=ncovcol+nqv+ntv+nqtv){
1.240     brouard  10202:        if(Tvard[k1][2] <=ncovcol){
                   10203:          Fixed[k]= 1;
                   10204:          Dummy[k]= 1;
                   10205:          modell[k].maintype= VTYPE;
                   10206:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * fixed dummy */
                   10207:          ncovv++; /* Varying variables without age */
                   10208:          TvarV[ncovv]=Tvar[k];
                   10209:          TvarVind[ncovv]=k;
                   10210:        }else if(Tvard[k1][2] <=ncovcol+nqv){
                   10211:          Fixed[k]= 1;
                   10212:          Dummy[k]= 1;
                   10213:          modell[k].maintype= VTYPE;
                   10214:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * fixed quantitative */
                   10215:          ncovv++; /* Varying variables without age */
                   10216:          TvarV[ncovv]=Tvar[k];
                   10217:          TvarVind[ncovv]=k;
                   10218:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv){
                   10219:          Fixed[k]= 1;
                   10220:          Dummy[k]= 1;
                   10221:          modell[k].maintype= VTYPE;
                   10222:          modell[k].subtype= VPDQ;              /*      Product time varying quantitative * time varying dummy */
                   10223:          ncovv++; /* Varying variables without age */
                   10224:          TvarV[ncovv]=Tvar[k];
                   10225:          TvarVind[ncovv]=k;
                   10226:        }else if(Tvard[k1][2] <=ncovcol+nqv+ntv+nqtv){
                   10227:          Fixed[k]= 1;
                   10228:          Dummy[k]= 1;
                   10229:          modell[k].maintype= VTYPE;
                   10230:          modell[k].subtype= VPQQ;              /*      Product time varying quantitative * time varying quantitative */
                   10231:          ncovv++; /* Varying variables without age */
                   10232:          TvarV[ncovv]=Tvar[k];
                   10233:          TvarVind[ncovv]=k;
                   10234:        }
1.227     brouard  10235:       }else{
1.240     brouard  10236:        printf("Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10237:        fprintf(ficlog,"Error unknown type of covariate: Tvard[%d][1]=%d,Tvard[%d][2]=%d\n",k1,Tvard[k1][1],k1,Tvard[k1][2]);
                   10238:       } /*end k1*/
1.225     brouard  10239:     }else{
1.226     brouard  10240:       printf("Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
                   10241:       fprintf(ficlog,"Error, current version can't treat for performance reasons, Tvar[%d]=%d, Typevar[%d]=%d\n", k, Tvar[k], k, Typevar[k]);
1.225     brouard  10242:     }
1.227     brouard  10243:     printf("Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
1.231     brouard  10244:     printf("           modell[%d].maintype=%d, modell[%d].subtype=%d\n",k,modell[k].maintype,k,modell[k].subtype);
1.227     brouard  10245:     fprintf(ficlog,"Decodemodel, k=%d, Tvar[%d]=V%d,Typevar=%d, Fixed=%d, Dummy=%d\n",k, k,Tvar[k],Typevar[k],Fixed[k],Dummy[k]);
                   10246:   }
                   10247:   /* Searching for doublons in the model */
                   10248:   for(k1=1; k1<= cptcovt;k1++){
                   10249:     for(k2=1; k2 <k1;k2++){
1.285     brouard  10250:       /* if((Typevar[k1]==Typevar[k2]) && (Fixed[Tvar[k1]]==Fixed[Tvar[k2]]) && (Dummy[Tvar[k1]]==Dummy[Tvar[k2]] )){ */
                   10251:       if((Typevar[k1]==Typevar[k2]) && (Fixed[k1]==Fixed[k2]) && (Dummy[k1]==Dummy[k2] )){
1.234     brouard  10252:        if((Typevar[k1] == 0 || Typevar[k1] == 1)){ /* Simple or age product */
                   10253:          if(Tvar[k1]==Tvar[k2]){
1.285     brouard  10254:            printf("Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]);
                   10255:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, Tvar[%d]=V%d, Tvar[%d]=V%d, Typevar=%d, Fixed=%d, Dummy=%d\n", model, k1,k2, k1, Tvar[k1], k2, Tvar[k2],Typevar[k1],Fixed[k1],Dummy[k1]); fflush(ficlog);
1.234     brouard  10256:            return(1);
                   10257:          }
                   10258:        }else if (Typevar[k1] ==2){
                   10259:          k3=Tposprod[k1];
                   10260:          k4=Tposprod[k2];
                   10261:          if( ((Tvard[k3][1]== Tvard[k4][1])&&(Tvard[k3][2]== Tvard[k4][2])) || ((Tvard[k3][1]== Tvard[k4][2])&&(Tvard[k3][2]== Tvard[k4][1])) ){
                   10262:            printf("Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]);
                   10263:            fprintf(ficlog,"Error duplication in the model=%s at positions (+) %d and %d, V%d*V%d, Typevar=%d, Fixed=%d, Dummy=%d\n",model, k1,k2, Tvard[k3][1], Tvard[k3][2],Typevar[k1],Fixed[Tvar[k1]],Dummy[Tvar[k1]]); fflush(ficlog);
                   10264:            return(1);
                   10265:          }
                   10266:        }
1.227     brouard  10267:       }
                   10268:     }
1.225     brouard  10269:   }
                   10270:   printf("ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
                   10271:   fprintf(ficlog,"ncoveff=%d, nqfveff=%d, ntveff=%d, nqtveff=%d, cptcovn=%d\n",ncoveff,nqfveff,ntveff,nqtveff,cptcovn);
1.234     brouard  10272:   printf("ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd,nsq);
                   10273:   fprintf(ficlog,"ncovf=%d, ncovv=%d, ncova=%d, nsd=%d, nsq=%d\n",ncovf,ncovv,ncova,nsd, nsq);
1.137     brouard  10274:   return (0); /* with covar[new additional covariate if product] and Tage if age */ 
1.164     brouard  10275:   /*endread:*/
1.225     brouard  10276:   printf("Exiting decodemodel: ");
                   10277:   return (1);
1.136     brouard  10278: }
                   10279: 
1.169     brouard  10280: int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
1.248     brouard  10281: {/* Check ages at death */
1.136     brouard  10282:   int i, m;
1.218     brouard  10283:   int firstone=0;
                   10284:   
1.136     brouard  10285:   for (i=1; i<=imx; i++) {
                   10286:     for(m=2; (m<= maxwav); m++) {
                   10287:       if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
                   10288:        anint[m][i]=9999;
1.216     brouard  10289:        if (s[m][i] != -2) /* Keeping initial status of unknown vital status */
                   10290:          s[m][i]=-1;
1.136     brouard  10291:       }
                   10292:       if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
1.260     brouard  10293:        *nberr = *nberr + 1;
1.218     brouard  10294:        if(firstone == 0){
                   10295:          firstone=1;
1.260     brouard  10296:        printf("Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\nOther similar cases in log file\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.218     brouard  10297:        }
1.262     brouard  10298:        fprintf(ficlog,"Warning (#%d)! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown but status is a death state %d at wave %d. If you don't know the vital status, please enter -2. If he/she is still alive but don't know the state, please code with '-1 or '.'. Here, we do not believe in a death, skipped.\n", *nberr,(int)moisdc[i],(int)andc[i],num[i],i,s[m][i],m);
1.260     brouard  10299:        s[m][i]=-1;  /* Droping the death status */
1.136     brouard  10300:       }
                   10301:       if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
1.169     brouard  10302:        (*nberr)++;
1.259     brouard  10303:        printf("Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\nOther similar cases in log file\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.262     brouard  10304:        fprintf(ficlog,"Error (#%d)! Month of death of individual %ld on line %d was unknown (%2d) (year of death is %4d) and status is a death state %d at wave %d. Please impute an arbitrary (or not) month and rerun. Currently this transition to death will be skipped (status is set to -2).\n", *nberr, num[i],i,(int)moisdc[i],(int)andc[i],s[m][i],m);
1.259     brouard  10305:        s[m][i]=-2; /* We prefer to skip it (and to skip it in version 0.8a1 too */
1.136     brouard  10306:       }
                   10307:     }
                   10308:   }
                   10309: 
                   10310:   for (i=1; i<=imx; i++)  {
                   10311:     agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
                   10312:     for(m=firstpass; (m<= lastpass); m++){
1.214     brouard  10313:       if(s[m][i] >0  || s[m][i]==-1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){ /* What if s[m][i]=-1 */
1.136     brouard  10314:        if (s[m][i] >= nlstate+1) {
1.169     brouard  10315:          if(agedc[i]>0){
                   10316:            if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
1.136     brouard  10317:              agev[m][i]=agedc[i];
1.214     brouard  10318:              /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
1.169     brouard  10319:            }else {
1.136     brouard  10320:              if ((int)andc[i]!=9999){
                   10321:                nbwarn++;
                   10322:                printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   10323:                fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   10324:                agev[m][i]=-1;
                   10325:              }
                   10326:            }
1.169     brouard  10327:          } /* agedc > 0 */
1.214     brouard  10328:        } /* end if */
1.136     brouard  10329:        else if(s[m][i] !=9){ /* Standard case, age in fractional
                   10330:                                 years but with the precision of a month */
                   10331:          agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
                   10332:          if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
                   10333:            agev[m][i]=1;
                   10334:          else if(agev[m][i] < *agemin){ 
                   10335:            *agemin=agev[m][i];
                   10336:            printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
                   10337:          }
                   10338:          else if(agev[m][i] >*agemax){
                   10339:            *agemax=agev[m][i];
1.156     brouard  10340:            /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
1.136     brouard  10341:          }
                   10342:          /*agev[m][i]=anint[m][i]-annais[i];*/
                   10343:          /*     agev[m][i] = age[i]+2*m;*/
1.214     brouard  10344:        } /* en if 9*/
1.136     brouard  10345:        else { /* =9 */
1.214     brouard  10346:          /* printf("Debug num[%d]=%ld s[%d][%d]=%d\n",i,num[i], m,i, s[m][i]); */
1.136     brouard  10347:          agev[m][i]=1;
                   10348:          s[m][i]=-1;
                   10349:        }
                   10350:       }
1.214     brouard  10351:       else if(s[m][i]==0) /*= 0 Unknown */
1.136     brouard  10352:        agev[m][i]=1;
1.214     brouard  10353:       else{
                   10354:        printf("Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10355:        fprintf(ficlog, "Warning, num[%d]=%ld, s[%d][%d]=%d\n", i, num[i], m, i,s[m][i]); 
                   10356:        agev[m][i]=0;
                   10357:       }
                   10358:     } /* End for lastpass */
                   10359:   }
1.136     brouard  10360:     
                   10361:   for (i=1; i<=imx; i++)  {
                   10362:     for(m=firstpass; (m<=lastpass); m++){
                   10363:       if (s[m][i] > (nlstate+ndeath)) {
1.169     brouard  10364:        (*nberr)++;
1.136     brouard  10365:        printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10366:        fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
                   10367:        return 1;
                   10368:       }
                   10369:     }
                   10370:   }
                   10371: 
                   10372:   /*for (i=1; i<=imx; i++){
                   10373:   for (m=firstpass; (m<lastpass); m++){
                   10374:      printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
                   10375: }
                   10376: 
                   10377: }*/
                   10378: 
                   10379: 
1.139     brouard  10380:   printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
                   10381:   fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
1.136     brouard  10382: 
                   10383:   return (0);
1.164     brouard  10384:  /* endread:*/
1.136     brouard  10385:     printf("Exiting calandcheckages: ");
                   10386:     return (1);
                   10387: }
                   10388: 
1.172     brouard  10389: #if defined(_MSC_VER)
                   10390: /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10391: /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
                   10392: //#include "stdafx.h"
                   10393: //#include <stdio.h>
                   10394: //#include <tchar.h>
                   10395: //#include <windows.h>
                   10396: //#include <iostream>
                   10397: typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
                   10398: 
                   10399: LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10400: 
                   10401: BOOL IsWow64()
                   10402: {
                   10403:        BOOL bIsWow64 = FALSE;
                   10404: 
                   10405:        //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
                   10406:        //  (HANDLE, PBOOL);
                   10407: 
                   10408:        //LPFN_ISWOW64PROCESS fnIsWow64Process;
                   10409: 
                   10410:        HMODULE module = GetModuleHandle(_T("kernel32"));
                   10411:        const char funcName[] = "IsWow64Process";
                   10412:        fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   10413:                GetProcAddress(module, funcName);
                   10414: 
                   10415:        if (NULL != fnIsWow64Process)
                   10416:        {
                   10417:                if (!fnIsWow64Process(GetCurrentProcess(),
                   10418:                        &bIsWow64))
                   10419:                        //throw std::exception("Unknown error");
                   10420:                        printf("Unknown error\n");
                   10421:        }
                   10422:        return bIsWow64 != FALSE;
                   10423: }
                   10424: #endif
1.177     brouard  10425: 
1.191     brouard  10426: void syscompilerinfo(int logged)
1.292     brouard  10427: {
                   10428: #include <stdint.h>
                   10429: 
                   10430:   /* #include "syscompilerinfo.h"*/
1.185     brouard  10431:    /* command line Intel compiler 32bit windows, XP compatible:*/
                   10432:    /* /GS /W3 /Gy
                   10433:       /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
                   10434:       "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
                   10435:       "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
1.186     brouard  10436:       /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
                   10437:    */ 
                   10438:    /* 64 bits */
1.185     brouard  10439:    /*
                   10440:      /GS /W3 /Gy
                   10441:      /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
                   10442:      /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
                   10443:      /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
                   10444:      "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
                   10445:    /* Optimization are useless and O3 is slower than O2 */
                   10446:    /*
                   10447:      /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
                   10448:      /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
                   10449:      /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
                   10450:      /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
                   10451:    */
1.186     brouard  10452:    /* Link is */ /* /OUT:"visual studio
1.185     brouard  10453:       2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
                   10454:       /PDB:"visual studio
                   10455:       2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
                   10456:       "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
                   10457:       "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
                   10458:       "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
                   10459:       /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
                   10460:       /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
                   10461:       uiAccess='false'"
                   10462:       /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
                   10463:       /NOLOGO /TLBID:1
                   10464:    */
1.292     brouard  10465: 
                   10466: 
1.177     brouard  10467: #if defined __INTEL_COMPILER
1.178     brouard  10468: #if defined(__GNUC__)
                   10469:        struct utsname sysInfo;  /* For Intel on Linux and OS/X */
                   10470: #endif
1.177     brouard  10471: #elif defined(__GNUC__) 
1.179     brouard  10472: #ifndef  __APPLE__
1.174     brouard  10473: #include <gnu/libc-version.h>  /* Only on gnu */
1.179     brouard  10474: #endif
1.177     brouard  10475:    struct utsname sysInfo;
1.178     brouard  10476:    int cross = CROSS;
                   10477:    if (cross){
                   10478:           printf("Cross-");
1.191     brouard  10479:           if(logged) fprintf(ficlog, "Cross-");
1.178     brouard  10480:    }
1.174     brouard  10481: #endif
                   10482: 
1.191     brouard  10483:    printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
1.169     brouard  10484: #if defined(__clang__)
1.191     brouard  10485:    printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");      /* Clang/LLVM. ---------------------------------------------- */
1.169     brouard  10486: #endif
                   10487: #if defined(__ICC) || defined(__INTEL_COMPILER)
1.191     brouard  10488:    printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
1.169     brouard  10489: #endif
                   10490: #if defined(__GNUC__) || defined(__GNUG__)
1.191     brouard  10491:    printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
1.169     brouard  10492: #endif
                   10493: #if defined(__HP_cc) || defined(__HP_aCC)
1.191     brouard  10494:    printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
1.169     brouard  10495: #endif
                   10496: #if defined(__IBMC__) || defined(__IBMCPP__)
1.191     brouard  10497:    printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
1.169     brouard  10498: #endif
                   10499: #if defined(_MSC_VER)
1.191     brouard  10500:    printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
1.169     brouard  10501: #endif
                   10502: #if defined(__PGI)
1.191     brouard  10503:    printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
1.169     brouard  10504: #endif
                   10505: #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
1.191     brouard  10506:    printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
1.167     brouard  10507: #endif
1.191     brouard  10508:    printf(" for "); if (logged) fprintf(ficlog, " for ");
1.169     brouard  10509:    
1.167     brouard  10510: // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
                   10511: #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
                   10512:     // Windows (x64 and x86)
1.191     brouard  10513:    printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
1.167     brouard  10514: #elif __unix__ // all unices, not all compilers
                   10515:     // Unix
1.191     brouard  10516:    printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
1.167     brouard  10517: #elif __linux__
                   10518:     // linux
1.191     brouard  10519:    printf("linux ");if(logged) fprintf(ficlog,"linux ");
1.167     brouard  10520: #elif __APPLE__
1.174     brouard  10521:     // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
1.191     brouard  10522:    printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
1.167     brouard  10523: #endif
                   10524: 
                   10525: /*  __MINGW32__          */
                   10526: /*  __CYGWIN__  */
                   10527: /* __MINGW64__  */
                   10528: // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
                   10529: /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
                   10530: /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
                   10531: /* _WIN64  // Defined for applications for Win64. */
                   10532: /* _M_X64 // Defined for compilations that target x64 processors. */
                   10533: /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
1.171     brouard  10534: 
1.167     brouard  10535: #if UINTPTR_MAX == 0xffffffff
1.191     brouard  10536:    printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
1.167     brouard  10537: #elif UINTPTR_MAX == 0xffffffffffffffff
1.191     brouard  10538:    printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
1.167     brouard  10539: #else
1.191     brouard  10540:    printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
1.167     brouard  10541: #endif
                   10542: 
1.169     brouard  10543: #if defined(__GNUC__)
                   10544: # if defined(__GNUC_PATCHLEVEL__)
                   10545: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10546:                             + __GNUC_MINOR__ * 100 \
                   10547:                             + __GNUC_PATCHLEVEL__)
                   10548: # else
                   10549: #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                   10550:                             + __GNUC_MINOR__ * 100)
                   10551: # endif
1.174     brouard  10552:    printf(" using GNU C version %d.\n", __GNUC_VERSION__);
1.191     brouard  10553:    if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
1.176     brouard  10554: 
                   10555:    if (uname(&sysInfo) != -1) {
                   10556:      printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.191     brouard  10557:         if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
1.176     brouard  10558:    }
                   10559:    else
                   10560:       perror("uname() error");
1.179     brouard  10561:    //#ifndef __INTEL_COMPILER 
                   10562: #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
1.174     brouard  10563:    printf("GNU libc version: %s\n", gnu_get_libc_version()); 
1.191     brouard  10564:    if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
1.177     brouard  10565: #endif
1.169     brouard  10566: #endif
1.172     brouard  10567: 
1.286     brouard  10568:    //   void main ()
1.172     brouard  10569:    //   {
1.169     brouard  10570: #if defined(_MSC_VER)
1.174     brouard  10571:    if (IsWow64()){
1.191     brouard  10572:           printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
                   10573:           if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
1.174     brouard  10574:    }
                   10575:    else{
1.191     brouard  10576:           printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
                   10577:           if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
1.174     brouard  10578:    }
1.172     brouard  10579:    //     printf("\nPress Enter to continue...");
                   10580:    //     getchar();
                   10581:    //   }
                   10582: 
1.169     brouard  10583: #endif
                   10584:    
1.167     brouard  10585: 
1.219     brouard  10586: }
1.136     brouard  10587: 
1.219     brouard  10588: int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
1.288     brouard  10589:   /*--------------- Prevalence limit  (forward period or forward stable prevalence) --------------*/
1.235     brouard  10590:   int i, j, k, i1, k4=0, nres=0 ;
1.202     brouard  10591:   /* double ftolpl = 1.e-10; */
1.180     brouard  10592:   double age, agebase, agelim;
1.203     brouard  10593:   double tot;
1.180     brouard  10594: 
1.202     brouard  10595:   strcpy(filerespl,"PL_");
                   10596:   strcat(filerespl,fileresu);
                   10597:   if((ficrespl=fopen(filerespl,"w"))==NULL) {
1.288     brouard  10598:     printf("Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
                   10599:     fprintf(ficlog,"Problem with forward period (stable) prevalence resultfile: %s\n", filerespl);return 1;
1.202     brouard  10600:   }
1.288     brouard  10601:   printf("\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
                   10602:   fprintf(ficlog,"\nComputing forward period (stable) prevalence: result on file '%s' \n", filerespl);
1.202     brouard  10603:   pstamp(ficrespl);
1.288     brouard  10604:   fprintf(ficrespl,"# Forward period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.202     brouard  10605:   fprintf(ficrespl,"#Age ");
                   10606:   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
                   10607:   fprintf(ficrespl,"\n");
1.180     brouard  10608:   
1.219     brouard  10609:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
1.180     brouard  10610: 
1.219     brouard  10611:   agebase=ageminpar;
                   10612:   agelim=agemaxpar;
1.180     brouard  10613: 
1.227     brouard  10614:   /* i1=pow(2,ncoveff); */
1.234     brouard  10615:   i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
1.219     brouard  10616:   if (cptcovn < 1){i1=1;}
1.180     brouard  10617: 
1.238     brouard  10618:   for(k=1; k<=i1;k++){ /* For each combination k of dummy covariates in the model */
                   10619:     for(nres=1; nres <= nresult; nres++){ /* For each resultline */
1.253     brouard  10620:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10621:        continue;
1.235     brouard  10622: 
1.238     brouard  10623:       /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10624:       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
                   10625:       //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
                   10626:       /* k=k+1; */
                   10627:       /* to clean */
                   10628:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10629:       fprintf(ficrespl,"#******");
                   10630:       printf("#******");
                   10631:       fprintf(ficlog,"#******");
                   10632:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10633:        fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); /* Here problem for varying dummy*/
                   10634:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10635:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10636:       }
                   10637:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10638:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10639:        fprintf(ficrespl," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10640:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10641:       }
                   10642:       fprintf(ficrespl,"******\n");
                   10643:       printf("******\n");
                   10644:       fprintf(ficlog,"******\n");
                   10645:       if(invalidvarcomb[k]){
                   10646:        printf("\nCombination (%d) ignored because no case \n",k); 
                   10647:        fprintf(ficrespl,"#Combination (%d) ignored because no case \n",k); 
                   10648:        fprintf(ficlog,"\nCombination (%d) ignored because no case \n",k); 
                   10649:        continue;
                   10650:       }
1.219     brouard  10651: 
1.238     brouard  10652:       fprintf(ficrespl,"#Age ");
                   10653:       for(j=1;j<=cptcoveff;j++) {
                   10654:        fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10655:       }
                   10656:       for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
                   10657:       fprintf(ficrespl,"Total Years_to_converge\n");
1.227     brouard  10658:     
1.238     brouard  10659:       for (age=agebase; age<=agelim; age++){
                   10660:        /* for (age=agebase; age<=agebase; age++){ */
                   10661:        prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k, nres);
                   10662:        fprintf(ficrespl,"%.0f ",age );
                   10663:        for(j=1;j<=cptcoveff;j++)
                   10664:          fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10665:        tot=0.;
                   10666:        for(i=1; i<=nlstate;i++){
                   10667:          tot +=  prlim[i][i];
                   10668:          fprintf(ficrespl," %.5f", prlim[i][i]);
                   10669:        }
                   10670:        fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
                   10671:       } /* Age */
                   10672:       /* was end of cptcod */
                   10673:     } /* cptcov */
                   10674:   } /* nres */
1.219     brouard  10675:   return 0;
1.180     brouard  10676: }
                   10677: 
1.218     brouard  10678: int back_prevalence_limit(double *p, double **bprlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp, double dateprev1,double dateprev2, int firstpass, int lastpass, int mobilavproj){
1.288     brouard  10679:        /*--------------- Back Prevalence limit  (backward stable prevalence) --------------*/
1.218     brouard  10680:        
                   10681:        /* Computes the back prevalence limit  for any combination      of covariate values 
                   10682:    * at any age between ageminpar and agemaxpar
                   10683:         */
1.235     brouard  10684:   int i, j, k, i1, nres=0 ;
1.217     brouard  10685:   /* double ftolpl = 1.e-10; */
                   10686:   double age, agebase, agelim;
                   10687:   double tot;
1.218     brouard  10688:   /* double ***mobaverage; */
                   10689:   /* double     **dnewm, **doldm, **dsavm;  /\* for use *\/ */
1.217     brouard  10690: 
                   10691:   strcpy(fileresplb,"PLB_");
                   10692:   strcat(fileresplb,fileresu);
                   10693:   if((ficresplb=fopen(fileresplb,"w"))==NULL) {
1.288     brouard  10694:     printf("Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
                   10695:     fprintf(ficlog,"Problem with backward prevalence resultfile: %s\n", fileresplb);return 1;
1.217     brouard  10696:   }
1.288     brouard  10697:   printf("Computing backward prevalence: result on file '%s' \n", fileresplb);
                   10698:   fprintf(ficlog,"Computing backward prevalence: result on file '%s' \n", fileresplb);
1.217     brouard  10699:   pstamp(ficresplb);
1.288     brouard  10700:   fprintf(ficresplb,"# Backward prevalence. Precision given by ftolpl=%g \n", ftolpl);
1.217     brouard  10701:   fprintf(ficresplb,"#Age ");
                   10702:   for(i=1; i<=nlstate;i++) fprintf(ficresplb,"%d-%d ",i,i);
                   10703:   fprintf(ficresplb,"\n");
                   10704:   
1.218     brouard  10705:   
                   10706:   /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
                   10707:   
                   10708:   agebase=ageminpar;
                   10709:   agelim=agemaxpar;
                   10710:   
                   10711:   
1.227     brouard  10712:   i1=pow(2,cptcoveff);
1.218     brouard  10713:   if (cptcovn < 1){i1=1;}
1.227     brouard  10714:   
1.238     brouard  10715:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10716:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10717:      if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10718:        continue;
                   10719:       //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
                   10720:       fprintf(ficresplb,"#******");
                   10721:       printf("#******");
                   10722:       fprintf(ficlog,"#******");
                   10723:       for(j=1;j<=cptcoveff ;j++) {/* all covariates */
                   10724:        fprintf(ficresplb," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10725:        printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10726:        fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10727:       }
                   10728:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10729:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10730:        fprintf(ficresplb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10731:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10732:       }
                   10733:       fprintf(ficresplb,"******\n");
                   10734:       printf("******\n");
                   10735:       fprintf(ficlog,"******\n");
                   10736:       if(invalidvarcomb[k]){
                   10737:        printf("\nCombination (%d) ignored because no cases \n",k); 
                   10738:        fprintf(ficresplb,"#Combination (%d) ignored because no cases \n",k); 
                   10739:        fprintf(ficlog,"\nCombination (%d) ignored because no cases \n",k); 
                   10740:        continue;
                   10741:       }
1.218     brouard  10742:     
1.238     brouard  10743:       fprintf(ficresplb,"#Age ");
                   10744:       for(j=1;j<=cptcoveff;j++) {
                   10745:        fprintf(ficresplb,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10746:       }
                   10747:       for(i=1; i<=nlstate;i++) fprintf(ficresplb,"  %d-%d   ",i,i);
                   10748:       fprintf(ficresplb,"Total Years_to_converge\n");
1.218     brouard  10749:     
                   10750:     
1.238     brouard  10751:       for (age=agebase; age<=agelim; age++){
                   10752:        /* for (age=agebase; age<=agebase; age++){ */
                   10753:        if(mobilavproj > 0){
                   10754:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, ageminpar, agemaxpar, oldm, savm, doldm, dsavm, ftolpl, ncvyearp, k); */
                   10755:          /* bprevalim(bprlim, mobaverage, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10756:          bprevalim(bprlim, mobaverage, nlstate, p, age, ftolpl, ncvyearp, k, nres);
1.238     brouard  10757:        }else if (mobilavproj == 0){
                   10758:          printf("There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10759:          fprintf(ficlog,"There is no chance to get back prevalence limit if data aren't non zero and summing to 1, please try a non null mobil_average(=%d) parameter or mobil_average=-1 if you want to try at your own risk.\n",mobilavproj);
                   10760:          exit(1);
                   10761:        }else{
                   10762:          /* bprevalim(bprlim, probs, nlstate, p, age, oldm, savm, dnewm, doldm, dsavm, ftolpl, ncvyearp, k); */
1.242     brouard  10763:          bprevalim(bprlim, probs, nlstate, p, age, ftolpl, ncvyearp, k,nres);
1.266     brouard  10764:          /* printf("TOTOT\n"); */
                   10765:           /* exit(1); */
1.238     brouard  10766:        }
                   10767:        fprintf(ficresplb,"%.0f ",age );
                   10768:        for(j=1;j<=cptcoveff;j++)
                   10769:          fprintf(ficresplb,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10770:        tot=0.;
                   10771:        for(i=1; i<=nlstate;i++){
                   10772:          tot +=  bprlim[i][i];
                   10773:          fprintf(ficresplb," %.5f", bprlim[i][i]);
                   10774:        }
                   10775:        fprintf(ficresplb," %.3f %d\n", tot, *ncvyearp);
                   10776:       } /* Age */
                   10777:       /* was end of cptcod */
1.255     brouard  10778:       /*fprintf(ficresplb,"\n");*/ /* Seems to be necessary for gnuplot only if two result lines and no covariate. */
1.238     brouard  10779:     } /* end of any combination */
                   10780:   } /* end of nres */  
1.218     brouard  10781:   /* hBijx(p, bage, fage); */
                   10782:   /* fclose(ficrespijb); */
                   10783:   
                   10784:   return 0;
1.217     brouard  10785: }
1.218     brouard  10786:  
1.180     brouard  10787: int hPijx(double *p, int bage, int fage){
                   10788:     /*------------- h Pij x at various ages ------------*/
                   10789: 
                   10790:   int stepsize;
                   10791:   int agelim;
                   10792:   int hstepm;
                   10793:   int nhstepm;
1.235     brouard  10794:   int h, i, i1, j, k, k4, nres=0;
1.180     brouard  10795: 
                   10796:   double agedeb;
                   10797:   double ***p3mat;
                   10798: 
1.201     brouard  10799:     strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
1.180     brouard  10800:     if((ficrespij=fopen(filerespij,"w"))==NULL) {
                   10801:       printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10802:       fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
                   10803:     }
                   10804:     printf("Computing pij: result on file '%s' \n", filerespij);
                   10805:     fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
                   10806:   
                   10807:     stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10808:     /*if (stepm<=24) stepsize=2;*/
                   10809: 
                   10810:     agelim=AGESUP;
                   10811:     hstepm=stepsize*YEARM; /* Every year of age */
                   10812:     hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
1.218     brouard  10813:                
1.180     brouard  10814:     /* hstepm=1;   aff par mois*/
                   10815:     pstamp(ficrespij);
                   10816:     fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
1.227     brouard  10817:     i1= pow(2,cptcoveff);
1.218     brouard  10818:                /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10819:                /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10820:                /*      k=k+1;  */
1.235     brouard  10821:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   10822:     for(k=1; k<=i1;k++){
1.253     brouard  10823:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  10824:        continue;
1.183     brouard  10825:       fprintf(ficrespij,"\n#****** ");
1.227     brouard  10826:       for(j=1;j<=cptcoveff;j++) 
1.198     brouard  10827:        fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  10828:       for (k4=1; k4<= nsq; k4++){ /* For each selected (single) quantitative value */
                   10829:        printf(" V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10830:        fprintf(ficrespij," V%d=%f ",Tvqresult[nres][k4],Tqresult[nres][k4]);
                   10831:       }
1.183     brouard  10832:       fprintf(ficrespij,"******\n");
                   10833:       
                   10834:       for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
                   10835:        nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
                   10836:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
                   10837:        
                   10838:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
1.180     brouard  10839:        
1.183     brouard  10840:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10841:        oldm=oldms;savm=savms;
1.235     brouard  10842:        hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k, nres);  
1.183     brouard  10843:        fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
                   10844:        for(i=1; i<=nlstate;i++)
                   10845:          for(j=1; j<=nlstate+ndeath;j++)
                   10846:            fprintf(ficrespij," %1d-%1d",i,j);
                   10847:        fprintf(ficrespij,"\n");
                   10848:        for (h=0; h<=nhstepm; h++){
                   10849:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10850:          fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
1.180     brouard  10851:          for(i=1; i<=nlstate;i++)
                   10852:            for(j=1; j<=nlstate+ndeath;j++)
1.183     brouard  10853:              fprintf(ficrespij," %.5f", p3mat[i][j][h]);
1.180     brouard  10854:          fprintf(ficrespij,"\n");
                   10855:        }
1.183     brouard  10856:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10857:        fprintf(ficrespij,"\n");
                   10858:       }
1.180     brouard  10859:       /*}*/
                   10860:     }
1.218     brouard  10861:     return 0;
1.180     brouard  10862: }
1.218     brouard  10863:  
                   10864:  int hBijx(double *p, int bage, int fage, double ***prevacurrent){
1.217     brouard  10865:     /*------------- h Bij x at various ages ------------*/
                   10866: 
                   10867:   int stepsize;
1.218     brouard  10868:   /* int agelim; */
                   10869:        int ageminl;
1.217     brouard  10870:   int hstepm;
                   10871:   int nhstepm;
1.238     brouard  10872:   int h, i, i1, j, k, nres;
1.218     brouard  10873:        
1.217     brouard  10874:   double agedeb;
                   10875:   double ***p3mat;
1.218     brouard  10876:        
                   10877:   strcpy(filerespijb,"PIJB_");  strcat(filerespijb,fileresu);
                   10878:   if((ficrespijb=fopen(filerespijb,"w"))==NULL) {
                   10879:     printf("Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10880:     fprintf(ficlog,"Problem with Pij back resultfile: %s\n", filerespijb); return 1;
                   10881:   }
                   10882:   printf("Computing pij back: result on file '%s' \n", filerespijb);
                   10883:   fprintf(ficlog,"Computing pij back: result on file '%s' \n", filerespijb);
                   10884:   
                   10885:   stepsize=(int) (stepm+YEARM-1)/YEARM;
                   10886:   /*if (stepm<=24) stepsize=2;*/
1.217     brouard  10887:   
1.218     brouard  10888:   /* agelim=AGESUP; */
1.289     brouard  10889:   ageminl=AGEINF; /* was 30 */
1.218     brouard  10890:   hstepm=stepsize*YEARM; /* Every year of age */
                   10891:   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */
                   10892:   
                   10893:   /* hstepm=1;   aff par mois*/
                   10894:   pstamp(ficrespijb);
1.255     brouard  10895:   fprintf(ficrespijb,"#****** h Bij x Back probability to be in state i at age x-h being in j at x: B1j+B2j+...=1 ");
1.227     brouard  10896:   i1= pow(2,cptcoveff);
1.218     brouard  10897:   /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
                   10898:   /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
                   10899:   /*   k=k+1;  */
1.238     brouard  10900:   for(nres=1; nres <= nresult; nres++){ /* For each resultline */
                   10901:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  10902:       if(i1 != 1 && TKresult[nres]!= k)
1.238     brouard  10903:        continue;
                   10904:       fprintf(ficrespijb,"\n#****** ");
                   10905:       for(j=1;j<=cptcoveff;j++)
                   10906:        fprintf(ficrespijb,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   10907:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   10908:        fprintf(ficrespijb," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   10909:       }
                   10910:       fprintf(ficrespijb,"******\n");
1.264     brouard  10911:       if(invalidvarcomb[k]){  /* Is it necessary here? */
1.238     brouard  10912:        fprintf(ficrespijb,"\n#Combination (%d) ignored because no cases \n",k); 
                   10913:        continue;
                   10914:       }
                   10915:       
                   10916:       /* for (agedeb=fage; agedeb>=bage; agedeb--){ /\* If stepm=6 months *\/ */
                   10917:       for (agedeb=bage; agedeb<=fage; agedeb++){ /* If stepm=6 months and estepm=24 (2 years) */
                   10918:        /* nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /\* Typically 20 years = 20*12/6=40 *\/ */
1.297     brouard  10919:        nhstepm=(int) rint((agedeb-ageminl)*YEARM/stepm+0.1)-1; /* Typically 20 years = 20*12/6=40 or 55*12/24=27.5-1.1=>27 */
                   10920:        nhstepm = nhstepm/hstepm; /* Typically 40/4=10, because estepm=24 stepm=6 => hstepm=24/6=4 or 28*/
1.238     brouard  10921:        
                   10922:        /*        nhstepm=nhstepm*YEARM; aff par mois*/
                   10923:        
1.266     brouard  10924:        p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm); /* We can't have it at an upper level because of nhstepm */
                   10925:        /* and memory limitations if stepm is small */
                   10926: 
1.238     brouard  10927:        /* oldm=oldms;savm=savms; */
                   10928:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);   */
1.267     brouard  10929:        hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm, k, nres);
1.238     brouard  10930:        /* hbxij(p3mat,nhstepm,agedeb,hstepm,p,prevacurrent,nlstate,stepm,oldm,savm, dnewm, doldm, dsavm, k); */
1.255     brouard  10931:        fprintf(ficrespijb,"# Cov Agex agex-h hbijx with i,j=");
1.217     brouard  10932:        for(i=1; i<=nlstate;i++)
                   10933:          for(j=1; j<=nlstate+ndeath;j++)
1.238     brouard  10934:            fprintf(ficrespijb," %1d-%1d",i,j);
1.217     brouard  10935:        fprintf(ficrespijb,"\n");
1.238     brouard  10936:        for (h=0; h<=nhstepm; h++){
                   10937:          /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
                   10938:          fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb - h*hstepm/YEARM*stepm );
                   10939:          /* fprintf(ficrespijb,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm ); */
                   10940:          for(i=1; i<=nlstate;i++)
                   10941:            for(j=1; j<=nlstate+ndeath;j++)
                   10942:              fprintf(ficrespijb," %.5f", p3mat[i][j][h]);
                   10943:          fprintf(ficrespijb,"\n");
                   10944:        }
                   10945:        free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
                   10946:        fprintf(ficrespijb,"\n");
                   10947:       } /* end age deb */
                   10948:     } /* end combination */
                   10949:   } /* end nres */
1.218     brouard  10950:   return 0;
                   10951:  } /*  hBijx */
1.217     brouard  10952: 
1.180     brouard  10953: 
1.136     brouard  10954: /***********************************************/
                   10955: /**************** Main Program *****************/
                   10956: /***********************************************/
                   10957: 
                   10958: int main(int argc, char *argv[])
                   10959: {
                   10960: #ifdef GSL
                   10961:   const gsl_multimin_fminimizer_type *T;
                   10962:   size_t iteri = 0, it;
                   10963:   int rval = GSL_CONTINUE;
                   10964:   int status = GSL_SUCCESS;
                   10965:   double ssval;
                   10966: #endif
                   10967:   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
1.290     brouard  10968:   int i,j, k, iter=0,m,size=100, cptcod; /* Suppressing because nobs */
                   10969:   /* int i,j, k, n=MAXN,iter=0,m,size=100, cptcod; */
1.209     brouard  10970:   int ncvyear=0; /* Number of years needed for the period prevalence to converge */
1.164     brouard  10971:   int jj, ll, li, lj, lk;
1.136     brouard  10972:   int numlinepar=0; /* Current linenumber of parameter file */
1.197     brouard  10973:   int num_filled;
1.136     brouard  10974:   int itimes;
                   10975:   int NDIM=2;
                   10976:   int vpopbased=0;
1.235     brouard  10977:   int nres=0;
1.258     brouard  10978:   int endishere=0;
1.277     brouard  10979:   int noffset=0;
1.274     brouard  10980:   int ncurrv=0; /* Temporary variable */
                   10981:   
1.164     brouard  10982:   char ca[32], cb[32];
1.136     brouard  10983:   /*  FILE *fichtm; *//* Html File */
                   10984:   /* FILE *ficgp;*/ /*Gnuplot File */
                   10985:   struct stat info;
1.191     brouard  10986:   double agedeb=0.;
1.194     brouard  10987: 
                   10988:   double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
1.219     brouard  10989:   double ageminout=-AGEOVERFLOW,agemaxout=AGEOVERFLOW; /* Smaller Age range redefined after movingaverage */
1.136     brouard  10990: 
1.165     brouard  10991:   double fret;
1.191     brouard  10992:   double dum=0.; /* Dummy variable */
1.136     brouard  10993:   double ***p3mat;
1.218     brouard  10994:   /* double ***mobaverage; */
1.164     brouard  10995: 
                   10996:   char line[MAXLINE];
1.197     brouard  10997:   char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
                   10998: 
1.234     brouard  10999:   char  modeltemp[MAXLINE];
1.230     brouard  11000:   char resultline[MAXLINE];
                   11001:   
1.136     brouard  11002:   char pathr[MAXLINE], pathimach[MAXLINE]; 
1.164     brouard  11003:   char *tok, *val; /* pathtot */
1.290     brouard  11004:   int firstobs=1, lastobs=10; /* nobs = lastobs-firstobs declared globally ;*/
1.195     brouard  11005:   int c,  h , cpt, c2;
1.191     brouard  11006:   int jl=0;
                   11007:   int i1, j1, jk, stepsize=0;
1.194     brouard  11008:   int count=0;
                   11009: 
1.164     brouard  11010:   int *tab; 
1.136     brouard  11011:   int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
1.296     brouard  11012:   /* double anprojd, mprojd, jprojd; /\* For eventual projections *\/ */
                   11013:   /* double anprojf, mprojf, jprojf; */
                   11014:   /* double jintmean,mintmean,aintmean;   */
                   11015:   int prvforecast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11016:   int prvbackcast = 0; /* Might be 1 (date of beginning of projection is a choice or 2 is the dateintmean */
                   11017:   double yrfproj= 10.0; /* Number of years of forward projections */
                   11018:   double yrbproj= 10.0; /* Number of years of backward projections */
                   11019:   int prevbcast=0; /* defined as global for mlikeli and mle, replacing backcast */
1.136     brouard  11020:   int mobilav=0,popforecast=0;
1.191     brouard  11021:   int hstepm=0, nhstepm=0;
1.136     brouard  11022:   int agemortsup;
                   11023:   float  sumlpop=0.;
                   11024:   double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
                   11025:   double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
                   11026: 
1.191     brouard  11027:   double bage=0, fage=110., age, agelim=0., agebase=0.;
1.136     brouard  11028:   double ftolpl=FTOL;
                   11029:   double **prlim;
1.217     brouard  11030:   double **bprlim;
1.136     brouard  11031:   double ***param; /* Matrix of parameters */
1.251     brouard  11032:   double ***paramstart; /* Matrix of starting parameter values */
                   11033:   double  *p, *pstart; /* p=param[1][1] pstart is for starting values guessed by freqsummary */
1.136     brouard  11034:   double **matcov; /* Matrix of covariance */
1.203     brouard  11035:   double **hess; /* Hessian matrix */
1.136     brouard  11036:   double ***delti3; /* Scale */
                   11037:   double *delti; /* Scale */
                   11038:   double ***eij, ***vareij;
                   11039:   double **varpl; /* Variances of prevalence limits by age */
1.269     brouard  11040: 
1.136     brouard  11041:   double *epj, vepp;
1.164     brouard  11042: 
1.273     brouard  11043:   double dateprev1, dateprev2;
1.296     brouard  11044:   double jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000, dateproj1=0, dateproj2=0, dateprojd=0, dateprojf=0;
                   11045:   double jback1=1,mback1=1,anback1=2000,jback2=1,mback2=1,anback2=2000, dateback1=0, dateback2=0, datebackd=0, datebackf=0;
                   11046: 
1.217     brouard  11047: 
1.136     brouard  11048:   double **ximort;
1.145     brouard  11049:   char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
1.136     brouard  11050:   int *dcwave;
                   11051: 
1.164     brouard  11052:   char z[1]="c";
1.136     brouard  11053: 
                   11054:   /*char  *strt;*/
                   11055:   char strtend[80];
1.126     brouard  11056: 
1.164     brouard  11057: 
1.126     brouard  11058: /*   setlocale (LC_ALL, ""); */
                   11059: /*   bindtextdomain (PACKAGE, LOCALEDIR); */
                   11060: /*   textdomain (PACKAGE); */
                   11061: /*   setlocale (LC_CTYPE, ""); */
                   11062: /*   setlocale (LC_MESSAGES, ""); */
                   11063: 
                   11064:   /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
1.157     brouard  11065:   rstart_time = time(NULL);  
                   11066:   /*  (void) gettimeofday(&start_time,&tzp);*/
                   11067:   start_time = *localtime(&rstart_time);
1.126     brouard  11068:   curr_time=start_time;
1.157     brouard  11069:   /*tml = *localtime(&start_time.tm_sec);*/
                   11070:   /* strcpy(strstart,asctime(&tml)); */
                   11071:   strcpy(strstart,asctime(&start_time));
1.126     brouard  11072: 
                   11073: /*  printf("Localtime (at start)=%s",strstart); */
1.157     brouard  11074: /*  tp.tm_sec = tp.tm_sec +86400; */
                   11075: /*  tm = *localtime(&start_time.tm_sec); */
1.126     brouard  11076: /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
                   11077: /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
                   11078: /*   tmg.tm_hour=tmg.tm_hour + 1; */
1.157     brouard  11079: /*   tp.tm_sec = mktime(&tmg); */
1.126     brouard  11080: /*   strt=asctime(&tmg); */
                   11081: /*   printf("Time(after) =%s",strstart);  */
                   11082: /*  (void) time (&time_value);
                   11083: *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
                   11084: *  tm = *localtime(&time_value);
                   11085: *  strstart=asctime(&tm);
                   11086: *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
                   11087: */
                   11088: 
                   11089:   nberr=0; /* Number of errors and warnings */
                   11090:   nbwarn=0;
1.184     brouard  11091: #ifdef WIN32
                   11092:   _getcwd(pathcd, size);
                   11093: #else
1.126     brouard  11094:   getcwd(pathcd, size);
1.184     brouard  11095: #endif
1.191     brouard  11096:   syscompilerinfo(0);
1.196     brouard  11097:   printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
1.126     brouard  11098:   if(argc <=1){
                   11099:     printf("\nEnter the parameter file name: ");
1.205     brouard  11100:     if(!fgets(pathr,FILENAMELENGTH,stdin)){
                   11101:       printf("ERROR Empty parameter file name\n");
                   11102:       goto end;
                   11103:     }
1.126     brouard  11104:     i=strlen(pathr);
                   11105:     if(pathr[i-1]=='\n')
                   11106:       pathr[i-1]='\0';
1.156     brouard  11107:     i=strlen(pathr);
1.205     brouard  11108:     if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
1.156     brouard  11109:       pathr[i-1]='\0';
1.205     brouard  11110:     }
                   11111:     i=strlen(pathr);
                   11112:     if( i==0 ){
                   11113:       printf("ERROR Empty parameter file name\n");
                   11114:       goto end;
                   11115:     }
                   11116:     for (tok = pathr; tok != NULL; ){
1.126     brouard  11117:       printf("Pathr |%s|\n",pathr);
                   11118:       while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
                   11119:       printf("val= |%s| pathr=%s\n",val,pathr);
                   11120:       strcpy (pathtot, val);
                   11121:       if(pathr[0] == '\0') break; /* Dirty */
                   11122:     }
                   11123:   }
1.281     brouard  11124:   else if (argc<=2){
                   11125:     strcpy(pathtot,argv[1]);
                   11126:   }
1.126     brouard  11127:   else{
                   11128:     strcpy(pathtot,argv[1]);
1.281     brouard  11129:     strcpy(z,argv[2]);
                   11130:     printf("\nargv[2]=%s z=%c\n",argv[2],z[0]);
1.126     brouard  11131:   }
                   11132:   /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
                   11133:   /*cygwin_split_path(pathtot,path,optionfile);
                   11134:     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
                   11135:   /* cutv(path,optionfile,pathtot,'\\');*/
                   11136: 
                   11137:   /* Split argv[0], imach program to get pathimach */
                   11138:   printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
                   11139:   split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11140:   printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
                   11141:  /*   strcpy(pathimach,argv[0]); */
                   11142:   /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
                   11143:   split(pathtot,path,optionfile,optionfilext,optionfilefiname);
                   11144:   printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
1.184     brouard  11145: #ifdef WIN32
                   11146:   _chdir(path); /* Can be a relative path */
                   11147:   if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
                   11148: #else
1.126     brouard  11149:   chdir(path); /* Can be a relative path */
1.184     brouard  11150:   if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
                   11151: #endif
                   11152:   printf("Current directory %s!\n",pathcd);
1.126     brouard  11153:   strcpy(command,"mkdir ");
                   11154:   strcat(command,optionfilefiname);
                   11155:   if((outcmd=system(command)) != 0){
1.169     brouard  11156:     printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
1.126     brouard  11157:     /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
                   11158:     /* fclose(ficlog); */
                   11159: /*     exit(1); */
                   11160:   }
                   11161: /*   if((imk=mkdir(optionfilefiname))<0){ */
                   11162: /*     perror("mkdir"); */
                   11163: /*   } */
                   11164: 
                   11165:   /*-------- arguments in the command line --------*/
                   11166: 
1.186     brouard  11167:   /* Main Log file */
1.126     brouard  11168:   strcat(filelog, optionfilefiname);
                   11169:   strcat(filelog,".log");    /* */
                   11170:   if((ficlog=fopen(filelog,"w"))==NULL)    {
                   11171:     printf("Problem with logfile %s\n",filelog);
                   11172:     goto end;
                   11173:   }
                   11174:   fprintf(ficlog,"Log filename:%s\n",filelog);
1.197     brouard  11175:   fprintf(ficlog,"Version %s %s",version,fullversion);
1.126     brouard  11176:   fprintf(ficlog,"\nEnter the parameter file name: \n");
                   11177:   fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
                   11178:  path=%s \n\
                   11179:  optionfile=%s\n\
                   11180:  optionfilext=%s\n\
1.156     brouard  11181:  optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
1.126     brouard  11182: 
1.197     brouard  11183:   syscompilerinfo(1);
1.167     brouard  11184: 
1.126     brouard  11185:   printf("Local time (at start):%s",strstart);
                   11186:   fprintf(ficlog,"Local time (at start): %s",strstart);
                   11187:   fflush(ficlog);
                   11188: /*   (void) gettimeofday(&curr_time,&tzp); */
1.157     brouard  11189: /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
1.126     brouard  11190: 
                   11191:   /* */
                   11192:   strcpy(fileres,"r");
                   11193:   strcat(fileres, optionfilefiname);
1.201     brouard  11194:   strcat(fileresu, optionfilefiname); /* Without r in front */
1.126     brouard  11195:   strcat(fileres,".txt");    /* Other files have txt extension */
1.201     brouard  11196:   strcat(fileresu,".txt");    /* Other files have txt extension */
1.126     brouard  11197: 
1.186     brouard  11198:   /* Main ---------arguments file --------*/
1.126     brouard  11199: 
                   11200:   if((ficpar=fopen(optionfile,"r"))==NULL)    {
1.155     brouard  11201:     printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
                   11202:     fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
1.126     brouard  11203:     fflush(ficlog);
1.149     brouard  11204:     /* goto end; */
                   11205:     exit(70); 
1.126     brouard  11206:   }
                   11207: 
                   11208:   strcpy(filereso,"o");
1.201     brouard  11209:   strcat(filereso,fileresu);
1.126     brouard  11210:   if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
                   11211:     printf("Problem with Output resultfile: %s\n", filereso);
                   11212:     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
                   11213:     fflush(ficlog);
                   11214:     goto end;
                   11215:   }
1.278     brouard  11216:       /*-------- Rewriting parameter file ----------*/
                   11217:   strcpy(rfileres,"r");    /* "Rparameterfile */
                   11218:   strcat(rfileres,optionfilefiname);    /* Parameter file first name */
                   11219:   strcat(rfileres,".");    /* */
                   11220:   strcat(rfileres,optionfilext);    /* Other files have txt extension */
                   11221:   if((ficres =fopen(rfileres,"w"))==NULL) {
                   11222:     printf("Problem writing new parameter file: %s\n", rfileres);goto end;
                   11223:     fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
                   11224:     fflush(ficlog);
                   11225:     goto end;
                   11226:   }
                   11227:   fprintf(ficres,"#IMaCh %s\n",version);
1.126     brouard  11228: 
1.278     brouard  11229:                                      
1.126     brouard  11230:   /* Reads comments: lines beginning with '#' */
                   11231:   numlinepar=0;
1.277     brouard  11232:   /* Is it a BOM UTF-8 Windows file? */
                   11233:   /* First parameter line */
1.197     brouard  11234:   while(fgets(line, MAXLINE, ficpar)) {
1.277     brouard  11235:     noffset=0;
                   11236:     if( line[0] == (char)0xEF && line[1] == (char)0xBB) /* EF BB BF */
                   11237:     {
                   11238:       noffset=noffset+3;
                   11239:       printf("# File is an UTF8 Bom.\n"); // 0xBF
                   11240:     }
1.302     brouard  11241: /*    else if( line[0] == (char)0xFE && line[1] == (char)0xFF)*/
                   11242:     else if( line[0] == (char)0xFF && line[1] == (char)0xFE)
1.277     brouard  11243:     {
                   11244:       noffset=noffset+2;
                   11245:       printf("# File is an UTF16BE BOM file\n");
                   11246:     }
                   11247:     else if( line[0] == 0 && line[1] == 0)
                   11248:     {
                   11249:       if( line[2] == (char)0xFE && line[3] == (char)0xFF){
                   11250:        noffset=noffset+4;
                   11251:        printf("# File is an UTF16BE BOM file\n");
                   11252:       }
                   11253:     } else{
                   11254:       ;/*printf(" Not a BOM file\n");*/
                   11255:     }
                   11256:   
1.197     brouard  11257:     /* If line starts with a # it is a comment */
1.277     brouard  11258:     if (line[noffset] == '#') {
1.197     brouard  11259:       numlinepar++;
                   11260:       fputs(line,stdout);
                   11261:       fputs(line,ficparo);
1.278     brouard  11262:       fputs(line,ficres);
1.197     brouard  11263:       fputs(line,ficlog);
                   11264:       continue;
                   11265:     }else
                   11266:       break;
                   11267:   }
                   11268:   if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                   11269:                        title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
                   11270:     if (num_filled != 5) {
                   11271:       printf("Should be 5 parameters\n");
1.283     brouard  11272:       fprintf(ficlog,"Should be 5 parameters\n");
1.197     brouard  11273:     }
1.126     brouard  11274:     numlinepar++;
1.197     brouard  11275:     printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.283     brouard  11276:     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11277:     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
                   11278:     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
1.197     brouard  11279:   }
                   11280:   /* Second parameter line */
                   11281:   while(fgets(line, MAXLINE, ficpar)) {
1.283     brouard  11282:     /* while(fscanf(ficpar,"%[^\n]", line)) { */
                   11283:     /* If line starts with a # it is a comment. Strangely fgets reads the EOL and fputs doesn't */
1.197     brouard  11284:     if (line[0] == '#') {
                   11285:       numlinepar++;
1.283     brouard  11286:       printf("%s",line);
                   11287:       fprintf(ficres,"%s",line);
                   11288:       fprintf(ficparo,"%s",line);
                   11289:       fprintf(ficlog,"%s",line);
1.197     brouard  11290:       continue;
                   11291:     }else
                   11292:       break;
                   11293:   }
1.223     brouard  11294:   if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                   11295:                        &ftol, &stepm, &ncovcol, &nqv, &ntv, &nqtv, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
                   11296:     if (num_filled != 11) {
                   11297:       printf("Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
1.209     brouard  11298:       printf("but line=%s\n",line);
1.283     brouard  11299:       fprintf(ficlog,"Not 11 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nqv=1 ntv=2 nqtv=1  nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
                   11300:       fprintf(ficlog,"but line=%s\n",line);
1.197     brouard  11301:     }
1.286     brouard  11302:     if( lastpass > maxwav){
                   11303:       printf("Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11304:       fprintf(ficlog,"Error (lastpass = %d) > (maxwav = %d)\n",lastpass, maxwav);
                   11305:       fflush(ficlog);
                   11306:       goto end;
                   11307:     }
                   11308:       printf("ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.283     brouard  11309:     fprintf(ficparo,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.286     brouard  11310:     fprintf(ficres,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, 0, weightopt);
1.283     brouard  11311:     fprintf(ficlog,"ftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, mle, weightopt);
1.126     brouard  11312:   }
1.203     brouard  11313:   /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
1.209     brouard  11314:   /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
1.197     brouard  11315:   /* Third parameter line */
                   11316:   while(fgets(line, MAXLINE, ficpar)) {
                   11317:     /* If line starts with a # it is a comment */
                   11318:     if (line[0] == '#') {
                   11319:       numlinepar++;
1.283     brouard  11320:       printf("%s",line);
                   11321:       fprintf(ficres,"%s",line);
                   11322:       fprintf(ficparo,"%s",line);
                   11323:       fprintf(ficlog,"%s",line);
1.197     brouard  11324:       continue;
                   11325:     }else
                   11326:       break;
                   11327:   }
1.201     brouard  11328:   if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
1.279     brouard  11329:     if (num_filled != 1){
1.302     brouard  11330:       printf("ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
                   11331:       fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age+' instead of '%s'\n",num_filled, line);
1.197     brouard  11332:       model[0]='\0';
                   11333:       goto end;
                   11334:     }
                   11335:     else{
                   11336:       if (model[0]=='+'){
                   11337:        for(i=1; i<=strlen(model);i++)
                   11338:          modeltemp[i-1]=model[i];
1.201     brouard  11339:        strcpy(model,modeltemp); 
1.197     brouard  11340:       }
                   11341:     }
1.199     brouard  11342:     /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
1.203     brouard  11343:     printf("model=1+age+%s\n",model);fflush(stdout);
1.283     brouard  11344:     fprintf(ficparo,"model=1+age+%s\n",model);fflush(stdout);
                   11345:     fprintf(ficres,"model=1+age+%s\n",model);fflush(stdout);
                   11346:     fprintf(ficlog,"model=1+age+%s\n",model);fflush(stdout);
1.197     brouard  11347:   }
                   11348:   /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
                   11349:   /* numlinepar=numlinepar+3; /\* In general *\/ */
                   11350:   /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
1.283     brouard  11351:   /* fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
                   11352:   /* fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol, nqv, ntv, nqtv, nlstate,ndeath,maxwav, mle, weightopt,model); */
1.126     brouard  11353:   fflush(ficlog);
1.190     brouard  11354:   /* if(model[0]=='#'|| model[0]== '\0'){ */
                   11355:   if(model[0]=='#'){
1.279     brouard  11356:     printf("Error in 'model' line: model should start with 'model=1+age+' and end without space \n \
                   11357:  'model=1+age+' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age' or \n \
                   11358:  'model=1+age+V1+V2' or 'model=1+age+V1+V2+V1*V2' etc. \n");           \
1.187     brouard  11359:     if(mle != -1){
1.279     brouard  11360:       printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter vectors and subdiagonal covariance matrix.\n");
1.187     brouard  11361:       exit(1);
                   11362:     }
                   11363:   }
1.126     brouard  11364:   while((c=getc(ficpar))=='#' && c!= EOF){
                   11365:     ungetc(c,ficpar);
                   11366:     fgets(line, MAXLINE, ficpar);
                   11367:     numlinepar++;
1.195     brouard  11368:     if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
                   11369:       z[0]=line[1];
                   11370:     }
                   11371:     /* printf("****line [1] = %c \n",line[1]); */
1.141     brouard  11372:     fputs(line, stdout);
                   11373:     //puts(line);
1.126     brouard  11374:     fputs(line,ficparo);
                   11375:     fputs(line,ficlog);
                   11376:   }
                   11377:   ungetc(c,ficpar);
                   11378: 
                   11379:    
1.290     brouard  11380:   covar=matrix(0,NCOVMAX,firstobs,lastobs);  /**< used in readdata */
                   11381:   if(nqv>=1)coqvar=matrix(1,nqv,firstobs,lastobs);  /**< Fixed quantitative covariate */
                   11382:   if(nqtv>=1)cotqvar=ma3x(1,maxwav,1,nqtv,firstobs,lastobs);  /**< Time varying quantitative covariate */
                   11383:   if(ntv+nqtv>=1)cotvar=ma3x(1,maxwav,1,ntv+nqtv,firstobs,lastobs);  /**< Time varying covariate (dummy and quantitative)*/
1.136     brouard  11384:   cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
                   11385:   /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
                   11386:      v1+v2*age+v2*v3 makes cptcovn = 3
                   11387:   */
                   11388:   if (strlen(model)>1) 
1.187     brouard  11389:     ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
1.145     brouard  11390:   else
1.187     brouard  11391:     ncovmodel=2; /* Constant and age */
1.133     brouard  11392:   nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
                   11393:   npar= nforce*ncovmodel; /* Number of parameters like aij*/
1.131     brouard  11394:   if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
                   11395:     printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11396:     fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
                   11397:     fflush(stdout);
                   11398:     fclose (ficlog);
                   11399:     goto end;
                   11400:   }
1.126     brouard  11401:   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11402:   delti=delti3[1][1];
                   11403:   /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
                   11404:   if(mle==-1){ /* Print a wizard for help writing covariance matrix */
1.247     brouard  11405: /* We could also provide initial parameters values giving by simple logistic regression 
                   11406:  * only one way, that is without matrix product. We will have nlstate maximizations */
                   11407:       /* for(i=1;i<nlstate;i++){ */
                   11408:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   11409:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   11410:       /* } */
1.126     brouard  11411:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.191     brouard  11412:     printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
                   11413:     fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11414:     free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   11415:     fclose (ficparo);
                   11416:     fclose (ficlog);
                   11417:     goto end;
                   11418:     exit(0);
1.220     brouard  11419:   }  else if(mle==-5) { /* Main Wizard */
1.126     brouard  11420:     prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
1.192     brouard  11421:     printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
                   11422:     fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
1.126     brouard  11423:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
                   11424:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11425:     hess=matrix(1,npar,1,npar);
1.220     brouard  11426:   }  else{ /* Begin of mle != -1 or -5 */
1.145     brouard  11427:     /* Read guessed parameters */
1.126     brouard  11428:     /* Reads comments: lines beginning with '#' */
                   11429:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11430:       ungetc(c,ficpar);
                   11431:       fgets(line, MAXLINE, ficpar);
                   11432:       numlinepar++;
1.141     brouard  11433:       fputs(line,stdout);
1.126     brouard  11434:       fputs(line,ficparo);
                   11435:       fputs(line,ficlog);
                   11436:     }
                   11437:     ungetc(c,ficpar);
                   11438:     
                   11439:     param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.251     brouard  11440:     paramstart= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
1.126     brouard  11441:     for(i=1; i <=nlstate; i++){
1.234     brouard  11442:       j=0;
1.126     brouard  11443:       for(jj=1; jj <=nlstate+ndeath; jj++){
1.234     brouard  11444:        if(jj==i) continue;
                   11445:        j++;
1.292     brouard  11446:        while((c=getc(ficpar))=='#' && c!= EOF){
                   11447:          ungetc(c,ficpar);
                   11448:          fgets(line, MAXLINE, ficpar);
                   11449:          numlinepar++;
                   11450:          fputs(line,stdout);
                   11451:          fputs(line,ficparo);
                   11452:          fputs(line,ficlog);
                   11453:        }
                   11454:        ungetc(c,ficpar);
1.234     brouard  11455:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11456:        if ((i1 != i) || (j1 != jj)){
                   11457:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
1.126     brouard  11458: It might be a problem of design; if ncovcol and the model are correct\n \
                   11459: run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
1.234     brouard  11460:          exit(1);
                   11461:        }
                   11462:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11463:        if(mle==1)
                   11464:          printf("%1d%1d",i,jj);
                   11465:        fprintf(ficlog,"%1d%1d",i,jj);
                   11466:        for(k=1; k<=ncovmodel;k++){
                   11467:          fscanf(ficpar," %lf",&param[i][j][k]);
                   11468:          if(mle==1){
                   11469:            printf(" %lf",param[i][j][k]);
                   11470:            fprintf(ficlog," %lf",param[i][j][k]);
                   11471:          }
                   11472:          else
                   11473:            fprintf(ficlog," %lf",param[i][j][k]);
                   11474:          fprintf(ficparo," %lf",param[i][j][k]);
                   11475:        }
                   11476:        fscanf(ficpar,"\n");
                   11477:        numlinepar++;
                   11478:        if(mle==1)
                   11479:          printf("\n");
                   11480:        fprintf(ficlog,"\n");
                   11481:        fprintf(ficparo,"\n");
1.126     brouard  11482:       }
                   11483:     }  
                   11484:     fflush(ficlog);
1.234     brouard  11485:     
1.251     brouard  11486:     /* Reads parameters values */
1.126     brouard  11487:     p=param[1][1];
1.251     brouard  11488:     pstart=paramstart[1][1];
1.126     brouard  11489:     
                   11490:     /* Reads comments: lines beginning with '#' */
                   11491:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11492:       ungetc(c,ficpar);
                   11493:       fgets(line, MAXLINE, ficpar);
                   11494:       numlinepar++;
1.141     brouard  11495:       fputs(line,stdout);
1.126     brouard  11496:       fputs(line,ficparo);
                   11497:       fputs(line,ficlog);
                   11498:     }
                   11499:     ungetc(c,ficpar);
                   11500: 
                   11501:     for(i=1; i <=nlstate; i++){
                   11502:       for(j=1; j <=nlstate+ndeath-1; j++){
1.234     brouard  11503:        fscanf(ficpar,"%1d%1d",&i1,&j1);
                   11504:        if ( (i1-i) * (j1-j) != 0){
                   11505:          printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
                   11506:          exit(1);
                   11507:        }
                   11508:        printf("%1d%1d",i,j);
                   11509:        fprintf(ficparo,"%1d%1d",i1,j1);
                   11510:        fprintf(ficlog,"%1d%1d",i1,j1);
                   11511:        for(k=1; k<=ncovmodel;k++){
                   11512:          fscanf(ficpar,"%le",&delti3[i][j][k]);
                   11513:          printf(" %le",delti3[i][j][k]);
                   11514:          fprintf(ficparo," %le",delti3[i][j][k]);
                   11515:          fprintf(ficlog," %le",delti3[i][j][k]);
                   11516:        }
                   11517:        fscanf(ficpar,"\n");
                   11518:        numlinepar++;
                   11519:        printf("\n");
                   11520:        fprintf(ficparo,"\n");
                   11521:        fprintf(ficlog,"\n");
1.126     brouard  11522:       }
                   11523:     }
                   11524:     fflush(ficlog);
1.234     brouard  11525:     
1.145     brouard  11526:     /* Reads covariance matrix */
1.126     brouard  11527:     delti=delti3[1][1];
1.220     brouard  11528:                
                   11529:                
1.126     brouard  11530:     /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
1.220     brouard  11531:                
1.126     brouard  11532:     /* Reads comments: lines beginning with '#' */
                   11533:     while((c=getc(ficpar))=='#' && c!= EOF){
                   11534:       ungetc(c,ficpar);
                   11535:       fgets(line, MAXLINE, ficpar);
                   11536:       numlinepar++;
1.141     brouard  11537:       fputs(line,stdout);
1.126     brouard  11538:       fputs(line,ficparo);
                   11539:       fputs(line,ficlog);
                   11540:     }
                   11541:     ungetc(c,ficpar);
1.220     brouard  11542:                
1.126     brouard  11543:     matcov=matrix(1,npar,1,npar);
1.203     brouard  11544:     hess=matrix(1,npar,1,npar);
1.131     brouard  11545:     for(i=1; i <=npar; i++)
                   11546:       for(j=1; j <=npar; j++) matcov[i][j]=0.;
1.220     brouard  11547:                
1.194     brouard  11548:     /* Scans npar lines */
1.126     brouard  11549:     for(i=1; i <=npar; i++){
1.226     brouard  11550:       count=fscanf(ficpar,"%1d%1d%d",&i1,&j1,&jk);
1.194     brouard  11551:       if(count != 3){
1.226     brouard  11552:        printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11553: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11554: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11555:        fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
1.194     brouard  11556: This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
                   11557: Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
1.226     brouard  11558:        exit(1);
1.220     brouard  11559:       }else{
1.226     brouard  11560:        if(mle==1)
                   11561:          printf("%1d%1d%d",i1,j1,jk);
                   11562:       }
                   11563:       fprintf(ficlog,"%1d%1d%d",i1,j1,jk);
                   11564:       fprintf(ficparo,"%1d%1d%d",i1,j1,jk);
1.126     brouard  11565:       for(j=1; j <=i; j++){
1.226     brouard  11566:        fscanf(ficpar," %le",&matcov[i][j]);
                   11567:        if(mle==1){
                   11568:          printf(" %.5le",matcov[i][j]);
                   11569:        }
                   11570:        fprintf(ficlog," %.5le",matcov[i][j]);
                   11571:        fprintf(ficparo," %.5le",matcov[i][j]);
1.126     brouard  11572:       }
                   11573:       fscanf(ficpar,"\n");
                   11574:       numlinepar++;
                   11575:       if(mle==1)
1.220     brouard  11576:                                printf("\n");
1.126     brouard  11577:       fprintf(ficlog,"\n");
                   11578:       fprintf(ficparo,"\n");
                   11579:     }
1.194     brouard  11580:     /* End of read covariance matrix npar lines */
1.126     brouard  11581:     for(i=1; i <=npar; i++)
                   11582:       for(j=i+1;j<=npar;j++)
1.226     brouard  11583:        matcov[i][j]=matcov[j][i];
1.126     brouard  11584:     
                   11585:     if(mle==1)
                   11586:       printf("\n");
                   11587:     fprintf(ficlog,"\n");
                   11588:     
                   11589:     fflush(ficlog);
                   11590:     
                   11591:   }    /* End of mle != -3 */
1.218     brouard  11592:   
1.186     brouard  11593:   /*  Main data
                   11594:    */
1.290     brouard  11595:   nobs=lastobs-firstobs+1; /* was = lastobs;*/
                   11596:   /* num=lvector(1,n); */
                   11597:   /* moisnais=vector(1,n); */
                   11598:   /* annais=vector(1,n); */
                   11599:   /* moisdc=vector(1,n); */
                   11600:   /* andc=vector(1,n); */
                   11601:   /* weight=vector(1,n); */
                   11602:   /* agedc=vector(1,n); */
                   11603:   /* cod=ivector(1,n); */
                   11604:   /* for(i=1;i<=n;i++){ */
                   11605:   num=lvector(firstobs,lastobs);
                   11606:   moisnais=vector(firstobs,lastobs);
                   11607:   annais=vector(firstobs,lastobs);
                   11608:   moisdc=vector(firstobs,lastobs);
                   11609:   andc=vector(firstobs,lastobs);
                   11610:   weight=vector(firstobs,lastobs);
                   11611:   agedc=vector(firstobs,lastobs);
                   11612:   cod=ivector(firstobs,lastobs);
                   11613:   for(i=firstobs;i<=lastobs;i++){
1.234     brouard  11614:     num[i]=0;
                   11615:     moisnais[i]=0;
                   11616:     annais[i]=0;
                   11617:     moisdc[i]=0;
                   11618:     andc[i]=0;
                   11619:     agedc[i]=0;
                   11620:     cod[i]=0;
                   11621:     weight[i]=1.0; /* Equal weights, 1 by default */
                   11622:   }
1.290     brouard  11623:   mint=matrix(1,maxwav,firstobs,lastobs);
                   11624:   anint=matrix(1,maxwav,firstobs,lastobs);
                   11625:   s=imatrix(1,maxwav+1,firstobs,lastobs); /* s[i][j] health state for wave i and individual j */ 
1.126     brouard  11626:   tab=ivector(1,NCOVMAX);
1.144     brouard  11627:   ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.192     brouard  11628:   ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
1.126     brouard  11629: 
1.136     brouard  11630:   /* Reads data from file datafile */
                   11631:   if (readdata(datafile, firstobs, lastobs, &imx)==1)
                   11632:     goto end;
                   11633: 
                   11634:   /* Calculation of the number of parameters from char model */
1.234     brouard  11635:   /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
1.137     brouard  11636:        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
                   11637:        k=3 V4 Tvar[k=3]= 4 (from V4)
                   11638:        k=2 V1 Tvar[k=2]= 1 (from V1)
                   11639:        k=1 Tvar[1]=2 (from V2)
1.234     brouard  11640:   */
                   11641:   
                   11642:   Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
                   11643:   TvarsDind=ivector(1,NCOVMAX); /*  */
                   11644:   TvarsD=ivector(1,NCOVMAX); /*  */
                   11645:   TvarsQind=ivector(1,NCOVMAX); /*  */
                   11646:   TvarsQ=ivector(1,NCOVMAX); /*  */
1.232     brouard  11647:   TvarF=ivector(1,NCOVMAX); /*  */
                   11648:   TvarFind=ivector(1,NCOVMAX); /*  */
                   11649:   TvarV=ivector(1,NCOVMAX); /*  */
                   11650:   TvarVind=ivector(1,NCOVMAX); /*  */
                   11651:   TvarA=ivector(1,NCOVMAX); /*  */
                   11652:   TvarAind=ivector(1,NCOVMAX); /*  */
1.231     brouard  11653:   TvarFD=ivector(1,NCOVMAX); /*  */
                   11654:   TvarFDind=ivector(1,NCOVMAX); /*  */
                   11655:   TvarFQ=ivector(1,NCOVMAX); /*  */
                   11656:   TvarFQind=ivector(1,NCOVMAX); /*  */
                   11657:   TvarVD=ivector(1,NCOVMAX); /*  */
                   11658:   TvarVDind=ivector(1,NCOVMAX); /*  */
                   11659:   TvarVQ=ivector(1,NCOVMAX); /*  */
                   11660:   TvarVQind=ivector(1,NCOVMAX); /*  */
                   11661: 
1.230     brouard  11662:   Tvalsel=vector(1,NCOVMAX); /*  */
1.233     brouard  11663:   Tvarsel=ivector(1,NCOVMAX); /*  */
1.226     brouard  11664:   Typevar=ivector(-1,NCOVMAX); /* -1 to 2 */
                   11665:   Fixed=ivector(-1,NCOVMAX); /* -1 to 3 */
                   11666:   Dummy=ivector(-1,NCOVMAX); /* -1 to 3 */
1.137     brouard  11667:   /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
                   11668:       For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
                   11669:       Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
                   11670:   */
                   11671:   /* For model-covariate k tells which data-covariate to use but
                   11672:     because this model-covariate is a construction we invent a new column
                   11673:     ncovcol + k1
                   11674:     If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
                   11675:     Tvar[3=V1*V4]=4+1 etc */
1.227     brouard  11676:   Tprod=ivector(1,NCOVMAX); /* Gives the k position of the k1 product */
                   11677:   Tposprod=ivector(1,NCOVMAX); /* Gives the k1 product from the k position */
1.137     brouard  11678:   /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
                   11679:      if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
1.227     brouard  11680:      Tposprod[k]=k1 , Tposprod[3]=1, Tposprod[5]=2 
1.137     brouard  11681:   */
1.145     brouard  11682:   Tvaraff=ivector(1,NCOVMAX); /* Unclear */
                   11683:   Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
1.141     brouard  11684:                            * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                   11685:                            * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
1.145     brouard  11686:   Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
1.137     brouard  11687:                         4 covariates (3 plus signs)
                   11688:                         Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                   11689:                      */  
1.230     brouard  11690:   Tmodelind=ivector(1,NCOVMAX);/** gives the k model position of an
1.227     brouard  11691:                                * individual dummy, fixed or varying:
                   11692:                                * Tmodelind[Tvaraff[3]]=9,Tvaraff[1]@9={4,
                   11693:                                * 3, 1, 0, 0, 0, 0, 0, 0},
1.230     brouard  11694:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1 , 
                   11695:                                * V1 df, V2 qf, V3 & V4 dv, V5 qv
                   11696:                                * Tmodelind[1]@9={9,0,3,2,}*/
                   11697:   TmodelInvind=ivector(1,NCOVMAX); /* TmodelInvind=Tvar[k]- ncovcol-nqv={5-2-1=2,*/
                   11698:   TmodelInvQind=ivector(1,NCOVMAX);/** gives the k model position of an
1.228     brouard  11699:                                * individual quantitative, fixed or varying:
                   11700:                                * Tmodelqind[1]=1,Tvaraff[1]@9={4,
                   11701:                                * 3, 1, 0, 0, 0, 0, 0, 0},
                   11702:                                * model=V5+V4+V3+V4*V3+V5*age+V2+V1*V2+V1*age+V1*/
1.186     brouard  11703: /* Main decodemodel */
                   11704: 
1.187     brouard  11705: 
1.223     brouard  11706:   if(decodemodel(model, lastobs) == 1) /* In order to get Tvar[k] V4+V3+V5 p Tvar[1]@3  = {4, 3, 5}*/
1.136     brouard  11707:     goto end;
                   11708: 
1.137     brouard  11709:   if((double)(lastobs-imx)/(double)imx > 1.10){
                   11710:     nbwarn++;
                   11711:     printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11712:     fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
                   11713:   }
1.136     brouard  11714:     /*  if(mle==1){*/
1.137     brouard  11715:   if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
                   11716:     for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
1.136     brouard  11717:   }
                   11718: 
                   11719:     /*-calculation of age at interview from date of interview and age at death -*/
                   11720:   agev=matrix(1,maxwav,1,imx);
                   11721: 
                   11722:   if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
                   11723:     goto end;
                   11724: 
1.126     brouard  11725: 
1.136     brouard  11726:   agegomp=(int)agemin;
1.290     brouard  11727:   free_vector(moisnais,firstobs,lastobs);
                   11728:   free_vector(annais,firstobs,lastobs);
1.126     brouard  11729:   /* free_matrix(mint,1,maxwav,1,n);
                   11730:      free_matrix(anint,1,maxwav,1,n);*/
1.215     brouard  11731:   /* free_vector(moisdc,1,n); */
                   11732:   /* free_vector(andc,1,n); */
1.145     brouard  11733:   /* */
                   11734:   
1.126     brouard  11735:   wav=ivector(1,imx);
1.214     brouard  11736:   /* dh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11737:   /* bh=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11738:   /* mw=imatrix(1,lastpass-firstpass+1,1,imx); */
                   11739:   dh=imatrix(1,lastpass-firstpass+2,1,imx); /* We are adding a wave if status is unknown at last wave but death occurs after last wave.*/
                   11740:   bh=imatrix(1,lastpass-firstpass+2,1,imx);
                   11741:   mw=imatrix(1,lastpass-firstpass+2,1,imx);
1.126     brouard  11742:    
                   11743:   /* Concatenates waves */
1.214     brouard  11744:   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
                   11745:      Death is a valid wave (if date is known).
                   11746:      mw[mi][i] is the number of (mi=1 to wav[i]) effective wave out of mi of individual i
                   11747:      dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
                   11748:      and mw[mi+1][i]. dh depends on stepm.
                   11749:   */
                   11750: 
1.126     brouard  11751:   concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
1.248     brouard  11752:   /* Concatenates waves */
1.145     brouard  11753:  
1.290     brouard  11754:   free_vector(moisdc,firstobs,lastobs);
                   11755:   free_vector(andc,firstobs,lastobs);
1.215     brouard  11756: 
1.126     brouard  11757:   /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
                   11758:   nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
                   11759:   ncodemax[1]=1;
1.145     brouard  11760:   Ndum =ivector(-1,NCOVMAX);  
1.225     brouard  11761:   cptcoveff=0;
1.220     brouard  11762:   if (ncovmodel-nagesqr > 2 ){ /* That is if covariate other than cst, age and age*age */
                   11763:     tricode(&cptcoveff,Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
1.227     brouard  11764:   }
                   11765:   
                   11766:   ncovcombmax=pow(2,cptcoveff);
                   11767:   invalidvarcomb=ivector(1, ncovcombmax); 
                   11768:   for(i=1;i<ncovcombmax;i++)
                   11769:     invalidvarcomb[i]=0;
                   11770:   
1.211     brouard  11771:   /* Nbcode gives the value of the lth modality (currently 1 to 2) of jth covariate, in
1.186     brouard  11772:      V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
1.211     brouard  11773:   /* 1 to ncodemax[j] which is the maximum value of this jth covariate */
1.227     brouard  11774:   
1.200     brouard  11775:   /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
1.198     brouard  11776:   /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
1.186     brouard  11777:   /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
1.211     brouard  11778:   /* nbcode[Tvaraff[j]][codtabm(h,j)]) : if there are only 2 modalities for a covariate j, 
                   11779:    * codtabm(h,j) gives its value classified at position h and nbcode gives how it is coded 
                   11780:    * (currently 0 or 1) in the data.
                   11781:    * In a loop on h=1 to 2**k, and a loop on j (=1 to k), we get the value of 
                   11782:    * corresponding modality (h,j).
                   11783:    */
                   11784: 
1.145     brouard  11785:   h=0;
                   11786:   /*if (cptcovn > 0) */
1.126     brouard  11787:   m=pow(2,cptcoveff);
                   11788:  
1.144     brouard  11789:          /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
1.211     brouard  11790:           * For k=4 covariates, h goes from 1 to m=2**k
                   11791:           * codtabm(h,k)=  (1 & (h-1) >> (k-1)) + 1;
                   11792:            * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
1.186     brouard  11793:           *     h\k   1     2     3     4
1.143     brouard  11794:           *______________________________  
                   11795:           *     1 i=1 1 i=1 1 i=1 1 i=1 1
                   11796:           *     2     2     1     1     1
                   11797:           *     3 i=2 1     2     1     1
                   11798:           *     4     2     2     1     1
                   11799:           *     5 i=3 1 i=2 1     2     1
                   11800:           *     6     2     1     2     1
                   11801:           *     7 i=4 1     2     2     1
                   11802:           *     8     2     2     2     1
1.197     brouard  11803:           *     9 i=5 1 i=3 1 i=2 1     2
                   11804:           *    10     2     1     1     2
                   11805:           *    11 i=6 1     2     1     2
                   11806:           *    12     2     2     1     2
                   11807:           *    13 i=7 1 i=4 1     2     2    
                   11808:           *    14     2     1     2     2
                   11809:           *    15 i=8 1     2     2     2
                   11810:           *    16     2     2     2     2
1.143     brouard  11811:           */
1.212     brouard  11812:   /* How to do the opposite? From combination h (=1 to 2**k) how to get the value on the covariates? */
1.211     brouard  11813:      /* from h=5 and m, we get then number of covariates k=log(m)/log(2)=4
                   11814:      * and the value of each covariate?
                   11815:      * V1=1, V2=1, V3=2, V4=1 ?
                   11816:      * h-1=4 and 4 is 0100 or reverse 0010, and +1 is 1121 ok.
                   11817:      * h=6, 6-1=5, 5 is 0101, 1010, 2121, V1=2nd, V2=1st, V3=2nd, V4=1st.
                   11818:      * In order to get the real value in the data, we use nbcode
                   11819:      * nbcode[Tvar[3][2nd]]=1 and nbcode[Tvar[4][1]]=0
                   11820:      * We are keeping this crazy system in order to be able (in the future?) 
                   11821:      * to have more than 2 values (0 or 1) for a covariate.
                   11822:      * #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
                   11823:      * h=6, k=2? h-1=5=0101, reverse 1010, +1=2121, k=2nd position: value is 1: codtabm(6,2)=1
                   11824:      *              bbbbbbbb
                   11825:      *              76543210     
                   11826:      *   h-1        00000101 (6-1=5)
1.219     brouard  11827:      *(h-1)>>(k-1)= 00000010 >> (2-1) = 1 right shift
1.211     brouard  11828:      *           &
                   11829:      *     1        00000001 (1)
1.219     brouard  11830:      *              00000000        = 1 & ((h-1) >> (k-1))
                   11831:      *          +1= 00000001 =1 
1.211     brouard  11832:      *
                   11833:      * h=14, k=3 => h'=h-1=13, k'=k-1=2
                   11834:      *          h'      1101 =2^3+2^2+0x2^1+2^0
                   11835:      *    >>k'            11
                   11836:      *          &   00000001
                   11837:      *            = 00000001
                   11838:      *      +1    = 00000010=2    =  codtabm(14,3)   
                   11839:      * Reverse h=6 and m=16?
                   11840:      * cptcoveff=log(16)/log(2)=4 covariate: 6-1=5=0101 reversed=1010 +1=2121 =>V1=2, V2=1, V3=2, V4=1.
                   11841:      * for (j=1 to cptcoveff) Vj=decodtabm(j,h,cptcoveff)
                   11842:      * decodtabm(h,j,cptcoveff)= (((h-1) >> (j-1)) & 1) +1 
                   11843:      * decodtabm(h,j,cptcoveff)= (h <= (1<<cptcoveff)?(((h-1) >> (j-1)) & 1) +1 : -1)
                   11844:      * V3=decodtabm(14,3,2**4)=2
                   11845:      *          h'=13   1101 =2^3+2^2+0x2^1+2^0
                   11846:      *(h-1) >> (j-1)    0011 =13 >> 2
                   11847:      *          &1 000000001
                   11848:      *           = 000000001
                   11849:      *         +1= 000000010 =2
                   11850:      *                  2211
                   11851:      *                  V1=1+1, V2=0+1, V3=1+1, V4=1+1
                   11852:      *                  V3=2
1.220     brouard  11853:                 * codtabm and decodtabm are identical
1.211     brouard  11854:      */
                   11855: 
1.145     brouard  11856: 
                   11857:  free_ivector(Ndum,-1,NCOVMAX);
                   11858: 
                   11859: 
1.126     brouard  11860:     
1.186     brouard  11861:   /* Initialisation of ----------- gnuplot -------------*/
1.126     brouard  11862:   strcpy(optionfilegnuplot,optionfilefiname);
                   11863:   if(mle==-3)
1.201     brouard  11864:     strcat(optionfilegnuplot,"-MORT_");
1.126     brouard  11865:   strcat(optionfilegnuplot,".gp");
                   11866: 
                   11867:   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
                   11868:     printf("Problem with file %s",optionfilegnuplot);
                   11869:   }
                   11870:   else{
1.204     brouard  11871:     fprintf(ficgp,"\n# IMaCh-%s\n", version); 
1.126     brouard  11872:     fprintf(ficgp,"# %s\n", optionfilegnuplot); 
1.141     brouard  11873:     //fprintf(ficgp,"set missing 'NaNq'\n");
                   11874:     fprintf(ficgp,"set datafile missing 'NaNq'\n");
1.126     brouard  11875:   }
                   11876:   /*  fclose(ficgp);*/
1.186     brouard  11877: 
                   11878: 
                   11879:   /* Initialisation of --------- index.htm --------*/
1.126     brouard  11880: 
                   11881:   strcpy(optionfilehtm,optionfilefiname); /* Main html file */
                   11882:   if(mle==-3)
1.201     brouard  11883:     strcat(optionfilehtm,"-MORT_");
1.126     brouard  11884:   strcat(optionfilehtm,".htm");
                   11885:   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
1.131     brouard  11886:     printf("Problem with %s \n",optionfilehtm);
                   11887:     exit(0);
1.126     brouard  11888:   }
                   11889: 
                   11890:   strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
                   11891:   strcat(optionfilehtmcov,"-cov.htm");
                   11892:   if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
                   11893:     printf("Problem with %s \n",optionfilehtmcov), exit(0);
                   11894:   }
                   11895:   else{
                   11896:   fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
                   11897: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11898: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
1.126     brouard  11899:          optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
                   11900:   }
                   11901: 
1.213     brouard  11902:   fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-2013-2016-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015-2018</a></font><br>  \
1.204     brouard  11903: <hr size=\"2\" color=\"#EC5E5E\"> \n\
                   11904: <font size=\"2\">IMaCh-%s <br> %s</font> \
1.126     brouard  11905: <hr size=\"2\" color=\"#EC5E5E\"> \n\
1.204     brouard  11906: Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
1.126     brouard  11907: \n\
                   11908: <hr  size=\"2\" color=\"#EC5E5E\">\
                   11909:  <ul><li><h4>Parameter files</h4>\n\
                   11910:  - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
                   11911:  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
                   11912:  - Log file of the run: <a href=\"%s\">%s</a><br>\n\
                   11913:  - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
                   11914:  - Date and time at start: %s</ul>\n",\
                   11915:          optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
                   11916:          optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
                   11917:          fileres,fileres,\
                   11918:          filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
                   11919:   fflush(fichtm);
                   11920: 
                   11921:   strcpy(pathr,path);
                   11922:   strcat(pathr,optionfilefiname);
1.184     brouard  11923: #ifdef WIN32
                   11924:   _chdir(optionfilefiname); /* Move to directory named optionfile */
                   11925: #else
1.126     brouard  11926:   chdir(optionfilefiname); /* Move to directory named optionfile */
1.184     brouard  11927: #endif
                   11928:          
1.126     brouard  11929:   
1.220     brouard  11930:   /* Calculates basic frequencies. Computes observed prevalence at single age 
                   11931:                 and for any valid combination of covariates
1.126     brouard  11932:      and prints on file fileres'p'. */
1.251     brouard  11933:   freqsummary(fileres, p, pstart, agemin, agemax, s, agev, nlstate, imx, Tvaraff, invalidvarcomb, nbcode, ncodemax,mint,anint,strstart, \
1.227     brouard  11934:              firstpass, lastpass,  stepm,  weightopt, model);
1.126     brouard  11935: 
                   11936:   fprintf(fichtm,"\n");
1.286     brouard  11937:   fprintf(fichtm,"<h4>Parameter line 2</h4><ul><li>Tolerance for the convergence of the likelihood: ftol=%g \n<li>Interval for the elementary matrix (in month): stepm=%d",\
1.274     brouard  11938:          ftol, stepm);
                   11939:   fprintf(fichtm,"\n<li>Number of fixed dummy covariates: ncovcol=%d ", ncovcol);
                   11940:   ncurrv=1;
                   11941:   for(i=ncurrv; i <=ncovcol; i++) fprintf(fichtm,"V%d ", i);
                   11942:   fprintf(fichtm,"\n<li> Number of fixed quantitative variables: nqv=%d ", nqv); 
                   11943:   ncurrv=i;
                   11944:   for(i=ncurrv; i <=ncurrv-1+nqv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11945:   fprintf(fichtm,"\n<li> Number of time varying (wave varying) dummy covariates: ntv=%d ", ntv);
1.274     brouard  11946:   ncurrv=i;
                   11947:   for(i=ncurrv; i <=ncurrv-1+ntv; i++) fprintf(fichtm,"V%d ", i);
1.290     brouard  11948:   fprintf(fichtm,"\n<li>Number of time varying  quantitative covariates: nqtv=%d ", nqtv);
1.274     brouard  11949:   ncurrv=i;
                   11950:   for(i=ncurrv; i <=ncurrv-1+nqtv; i++) fprintf(fichtm,"V%d ", i);
                   11951:   fprintf(fichtm,"\n<li>Weights column \n<br>Number of alive states: nlstate=%d <br>Number of death states (not really implemented): ndeath=%d \n<li>Number of waves: maxwav=%d \n<li>Parameter for maximization (1), using parameter values (0), for design of parameters and variance-covariance matrix: mle=%d \n<li>Does the weight column be taken into account (1), or not (0): weight=%d</ul>\n", \
                   11952:           nlstate, ndeath, maxwav, mle, weightopt);
                   11953: 
                   11954:   fprintf(fichtm,"<h4> Diagram of states <a href=\"%s_.svg\">%s_.svg</a></h4> \n\
                   11955: <img src=\"%s_.svg\">", subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"),subdirf2(optionfilefiname,"D_"));
                   11956: 
                   11957:   
                   11958:   fprintf(fichtm,"\n<h4>Some descriptive statistics </h4>\n<br>Total number of observations=%d <br>\n\
1.126     brouard  11959: Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
                   11960: Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
1.274     brouard  11961:   imx,agemin,agemax,jmin,jmax,jmean);
1.126     brouard  11962:   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
1.268     brouard  11963:   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11964:   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11965:   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
                   11966:   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
1.218     brouard  11967: 
1.126     brouard  11968:   /* For Powell, parameters are in a vector p[] starting at p[1]
                   11969:      so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
                   11970:   p=param[1][1]; /* *(*(*(param +1)+1)+0) */
                   11971: 
                   11972:   globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
1.186     brouard  11973:   /* For mortality only */
1.126     brouard  11974:   if (mle==-3){
1.136     brouard  11975:     ximort=matrix(1,NDIM,1,NDIM); 
1.248     brouard  11976:     for(i=1;i<=NDIM;i++)
                   11977:       for(j=1;j<=NDIM;j++)
                   11978:        ximort[i][j]=0.;
1.186     brouard  11979:     /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
1.290     brouard  11980:     cens=ivector(firstobs,lastobs);
                   11981:     ageexmed=vector(firstobs,lastobs);
                   11982:     agecens=vector(firstobs,lastobs);
                   11983:     dcwave=ivector(firstobs,lastobs);
1.223     brouard  11984:                
1.126     brouard  11985:     for (i=1; i<=imx; i++){
                   11986:       dcwave[i]=-1;
                   11987:       for (m=firstpass; m<=lastpass; m++)
1.226     brouard  11988:        if (s[m][i]>nlstate) {
                   11989:          dcwave[i]=m;
                   11990:          /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
                   11991:          break;
                   11992:        }
1.126     brouard  11993:     }
1.226     brouard  11994:     
1.126     brouard  11995:     for (i=1; i<=imx; i++) {
                   11996:       if (wav[i]>0){
1.226     brouard  11997:        ageexmed[i]=agev[mw[1][i]][i];
                   11998:        j=wav[i];
                   11999:        agecens[i]=1.; 
                   12000:        
                   12001:        if (ageexmed[i]> 1 && wav[i] > 0){
                   12002:          agecens[i]=agev[mw[j][i]][i];
                   12003:          cens[i]= 1;
                   12004:        }else if (ageexmed[i]< 1) 
                   12005:          cens[i]= -1;
                   12006:        if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
                   12007:          cens[i]=0 ;
1.126     brouard  12008:       }
                   12009:       else cens[i]=-1;
                   12010:     }
                   12011:     
                   12012:     for (i=1;i<=NDIM;i++) {
                   12013:       for (j=1;j<=NDIM;j++)
1.226     brouard  12014:        ximort[i][j]=(i == j ? 1.0 : 0.0);
1.126     brouard  12015:     }
                   12016:     
1.302     brouard  12017:     p[1]=0.0268; p[NDIM]=0.083;
                   12018:     /* printf("%lf %lf", p[1], p[2]); */
1.126     brouard  12019:     
                   12020:     
1.136     brouard  12021: #ifdef GSL
                   12022:     printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
1.162     brouard  12023: #else
1.126     brouard  12024:     printf("Powell\n");  fprintf(ficlog,"Powell\n");
1.136     brouard  12025: #endif
1.201     brouard  12026:     strcpy(filerespow,"POW-MORT_"); 
                   12027:     strcat(filerespow,fileresu);
1.126     brouard  12028:     if((ficrespow=fopen(filerespow,"w"))==NULL) {
                   12029:       printf("Problem with resultfile: %s\n", filerespow);
                   12030:       fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
                   12031:     }
1.136     brouard  12032: #ifdef GSL
                   12033:     fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
1.162     brouard  12034: #else
1.126     brouard  12035:     fprintf(ficrespow,"# Powell\n# iter -2*LL");
1.136     brouard  12036: #endif
1.126     brouard  12037:     /*  for (i=1;i<=nlstate;i++)
                   12038:        for(j=1;j<=nlstate+ndeath;j++)
                   12039:        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
                   12040:     */
                   12041:     fprintf(ficrespow,"\n");
1.136     brouard  12042: #ifdef GSL
                   12043:     /* gsl starts here */ 
                   12044:     T = gsl_multimin_fminimizer_nmsimplex;
                   12045:     gsl_multimin_fminimizer *sfm = NULL;
                   12046:     gsl_vector *ss, *x;
                   12047:     gsl_multimin_function minex_func;
                   12048: 
                   12049:     /* Initial vertex size vector */
                   12050:     ss = gsl_vector_alloc (NDIM);
                   12051:     
                   12052:     if (ss == NULL){
                   12053:       GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
                   12054:     }
                   12055:     /* Set all step sizes to 1 */
                   12056:     gsl_vector_set_all (ss, 0.001);
                   12057: 
                   12058:     /* Starting point */
1.126     brouard  12059:     
1.136     brouard  12060:     x = gsl_vector_alloc (NDIM);
                   12061:     
                   12062:     if (x == NULL){
                   12063:       gsl_vector_free(ss);
                   12064:       GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
                   12065:     }
                   12066:   
                   12067:     /* Initialize method and iterate */
                   12068:     /*     p[1]=0.0268; p[NDIM]=0.083; */
1.186     brouard  12069:     /*     gsl_vector_set(x, 0, 0.0268); */
                   12070:     /*     gsl_vector_set(x, 1, 0.083); */
1.136     brouard  12071:     gsl_vector_set(x, 0, p[1]);
                   12072:     gsl_vector_set(x, 1, p[2]);
                   12073: 
                   12074:     minex_func.f = &gompertz_f;
                   12075:     minex_func.n = NDIM;
                   12076:     minex_func.params = (void *)&p; /* ??? */
                   12077:     
                   12078:     sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
                   12079:     gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
                   12080:     
                   12081:     printf("Iterations beginning .....\n\n");
                   12082:     printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
                   12083: 
                   12084:     iteri=0;
                   12085:     while (rval == GSL_CONTINUE){
                   12086:       iteri++;
                   12087:       status = gsl_multimin_fminimizer_iterate(sfm);
                   12088:       
                   12089:       if (status) printf("error: %s\n", gsl_strerror (status));
                   12090:       fflush(0);
                   12091:       
                   12092:       if (status) 
                   12093:         break;
                   12094:       
                   12095:       rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
                   12096:       ssval = gsl_multimin_fminimizer_size (sfm);
                   12097:       
                   12098:       if (rval == GSL_SUCCESS)
                   12099:         printf ("converged to a local maximum at\n");
                   12100:       
                   12101:       printf("%5d ", iteri);
                   12102:       for (it = 0; it < NDIM; it++){
                   12103:        printf ("%10.5f ", gsl_vector_get (sfm->x, it));
                   12104:       }
                   12105:       printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
                   12106:     }
                   12107:     
                   12108:     printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
                   12109:     
                   12110:     gsl_vector_free(x); /* initial values */
                   12111:     gsl_vector_free(ss); /* inital step size */
                   12112:     for (it=0; it<NDIM; it++){
                   12113:       p[it+1]=gsl_vector_get(sfm->x,it);
                   12114:       fprintf(ficrespow," %.12lf", p[it]);
                   12115:     }
                   12116:     gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
                   12117: #endif
                   12118: #ifdef POWELL
                   12119:      powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
                   12120: #endif  
1.126     brouard  12121:     fclose(ficrespow);
                   12122:     
1.203     brouard  12123:     hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
1.126     brouard  12124: 
                   12125:     for(i=1; i <=NDIM; i++)
                   12126:       for(j=i+1;j<=NDIM;j++)
1.220     brouard  12127:                                matcov[i][j]=matcov[j][i];
1.126     brouard  12128:     
                   12129:     printf("\nCovariance matrix\n ");
1.203     brouard  12130:     fprintf(ficlog,"\nCovariance matrix\n ");
1.126     brouard  12131:     for(i=1; i <=NDIM; i++) {
                   12132:       for(j=1;j<=NDIM;j++){ 
1.220     brouard  12133:                                printf("%f ",matcov[i][j]);
                   12134:                                fprintf(ficlog,"%f ",matcov[i][j]);
1.126     brouard  12135:       }
1.203     brouard  12136:       printf("\n ");  fprintf(ficlog,"\n ");
1.126     brouard  12137:     }
                   12138:     
                   12139:     printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
1.193     brouard  12140:     for (i=1;i<=NDIM;i++) {
1.126     brouard  12141:       printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
1.193     brouard  12142:       fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
                   12143:     }
1.302     brouard  12144:     lsurv=vector(agegomp,AGESUP);
                   12145:     lpop=vector(agegomp,AGESUP);
                   12146:     tpop=vector(agegomp,AGESUP);
1.126     brouard  12147:     lsurv[agegomp]=100000;
                   12148:     
                   12149:     for (k=agegomp;k<=AGESUP;k++) {
                   12150:       agemortsup=k;
                   12151:       if (p[1]*exp(p[2]*(k-agegomp))>1) break;
                   12152:     }
                   12153:     
                   12154:     for (k=agegomp;k<agemortsup;k++)
                   12155:       lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
                   12156:     
                   12157:     for (k=agegomp;k<agemortsup;k++){
                   12158:       lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
                   12159:       sumlpop=sumlpop+lpop[k];
                   12160:     }
                   12161:     
                   12162:     tpop[agegomp]=sumlpop;
                   12163:     for (k=agegomp;k<(agemortsup-3);k++){
                   12164:       /*  tpop[k+1]=2;*/
                   12165:       tpop[k+1]=tpop[k]-lpop[k];
                   12166:     }
                   12167:     
                   12168:     
                   12169:     printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
                   12170:     for (k=agegomp;k<(agemortsup-2);k++) 
                   12171:       printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
                   12172:     
                   12173:     
                   12174:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.220     brouard  12175:                ageminpar=50;
                   12176:                agemaxpar=100;
1.194     brouard  12177:     if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
                   12178:        printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12179: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12180: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
                   12181:        fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
                   12182: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12183: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12184:     }else{
                   12185:                        printf("Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
                   12186:                        fprintf(ficlog,"Warning! ageminpar %f and agemaxpar %f have been fixed because for simplification until it is fixed...\n\n",ageminpar,agemaxpar);
1.201     brouard  12187:       printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
1.220     brouard  12188:                }
1.201     brouard  12189:     printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
1.126     brouard  12190:                     stepm, weightopt,\
                   12191:                     model,imx,p,matcov,agemortsup);
                   12192:     
1.302     brouard  12193:     free_vector(lsurv,agegomp,AGESUP);
                   12194:     free_vector(lpop,agegomp,AGESUP);
                   12195:     free_vector(tpop,agegomp,AGESUP);
1.220     brouard  12196:     free_matrix(ximort,1,NDIM,1,NDIM);
1.290     brouard  12197:     free_ivector(dcwave,firstobs,lastobs);
                   12198:     free_vector(agecens,firstobs,lastobs);
                   12199:     free_vector(ageexmed,firstobs,lastobs);
                   12200:     free_ivector(cens,firstobs,lastobs);
1.220     brouard  12201: #ifdef GSL
1.136     brouard  12202: #endif
1.186     brouard  12203:   } /* Endof if mle==-3 mortality only */
1.205     brouard  12204:   /* Standard  */
                   12205:   else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
                   12206:     globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12207:     /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
1.132     brouard  12208:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
1.126     brouard  12209:     printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12210:     for (k=1; k<=npar;k++)
                   12211:       printf(" %d %8.5f",k,p[k]);
                   12212:     printf("\n");
1.205     brouard  12213:     if(mle>=1){ /* Could be 1 or 2, Real Maximization */
                   12214:       /* mlikeli uses func not funcone */
1.247     brouard  12215:       /* for(i=1;i<nlstate;i++){ */
                   12216:       /*       /\*reducing xi for 1 to npar to 1 to ncovmodel; *\/ */
                   12217:       /*    mlikeli(ficres,p, ncovmodel, ncovmodel, nlstate, ftol, funcnoprod); */
                   12218:       /* } */
1.205     brouard  12219:       mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
                   12220:     }
                   12221:     if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
                   12222:       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
                   12223:       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
                   12224:       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12225:     }
                   12226:     globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
1.126     brouard  12227:     likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
                   12228:     printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
                   12229:     for (k=1; k<=npar;k++)
                   12230:       printf(" %d %8.5f",k,p[k]);
                   12231:     printf("\n");
                   12232:     
                   12233:     /*--------- results files --------------*/
1.283     brouard  12234:     /* fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nqv=%d ntv=%d nqtv=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nqv, ntv, nqtv, nlstate, ndeath, maxwav, weightopt,model); */
1.126     brouard  12235:     
                   12236:     
                   12237:     fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12238:     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12239:     fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
                   12240:     for(i=1,jk=1; i <=nlstate; i++){
                   12241:       for(k=1; k <=(nlstate+ndeath); k++){
1.225     brouard  12242:        if (k != i) {
                   12243:          printf("%d%d ",i,k);
                   12244:          fprintf(ficlog,"%d%d ",i,k);
                   12245:          fprintf(ficres,"%1d%1d ",i,k);
                   12246:          for(j=1; j <=ncovmodel; j++){
                   12247:            printf("%12.7f ",p[jk]);
                   12248:            fprintf(ficlog,"%12.7f ",p[jk]);
                   12249:            fprintf(ficres,"%12.7f ",p[jk]);
                   12250:            jk++; 
                   12251:          }
                   12252:          printf("\n");
                   12253:          fprintf(ficlog,"\n");
                   12254:          fprintf(ficres,"\n");
                   12255:        }
1.126     brouard  12256:       }
                   12257:     }
1.203     brouard  12258:     if(mle != 0){
                   12259:       /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
1.126     brouard  12260:       ftolhess=ftol; /* Usually correct */
1.203     brouard  12261:       hesscov(matcov, hess, p, npar, delti, ftolhess, func);
                   12262:       printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12263:       fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
                   12264:       for(i=1,jk=1; i <=nlstate; i++){
1.225     brouard  12265:        for(k=1; k <=(nlstate+ndeath); k++){
                   12266:          if (k != i) {
                   12267:            printf("%d%d ",i,k);
                   12268:            fprintf(ficlog,"%d%d ",i,k);
                   12269:            for(j=1; j <=ncovmodel; j++){
                   12270:              printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12271:              fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                   12272:              jk++; 
                   12273:            }
                   12274:            printf("\n");
                   12275:            fprintf(ficlog,"\n");
                   12276:          }
                   12277:        }
1.193     brouard  12278:       }
1.203     brouard  12279:     } /* end of hesscov and Wald tests */
1.225     brouard  12280:     
1.203     brouard  12281:     /*  */
1.126     brouard  12282:     fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
                   12283:     printf("# Scales (for hessian or gradient estimation)\n");
                   12284:     fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
                   12285:     for(i=1,jk=1; i <=nlstate; i++){
                   12286:       for(j=1; j <=nlstate+ndeath; j++){
1.225     brouard  12287:        if (j!=i) {
                   12288:          fprintf(ficres,"%1d%1d",i,j);
                   12289:          printf("%1d%1d",i,j);
                   12290:          fprintf(ficlog,"%1d%1d",i,j);
                   12291:          for(k=1; k<=ncovmodel;k++){
                   12292:            printf(" %.5e",delti[jk]);
                   12293:            fprintf(ficlog," %.5e",delti[jk]);
                   12294:            fprintf(ficres," %.5e",delti[jk]);
                   12295:            jk++;
                   12296:          }
                   12297:          printf("\n");
                   12298:          fprintf(ficlog,"\n");
                   12299:          fprintf(ficres,"\n");
                   12300:        }
1.126     brouard  12301:       }
                   12302:     }
                   12303:     
                   12304:     fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
1.203     brouard  12305:     if(mle >= 1) /* To big for the screen */
1.126     brouard  12306:       printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12307:     fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
                   12308:     /* # 121 Var(a12)\n\ */
                   12309:     /* # 122 Cov(b12,a12) Var(b12)\n\ */
                   12310:     /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
                   12311:     /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
                   12312:     /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
                   12313:     /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
                   12314:     /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
                   12315:     /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
                   12316:     
                   12317:     
                   12318:     /* Just to have a covariance matrix which will be more understandable
                   12319:        even is we still don't want to manage dictionary of variables
                   12320:     */
                   12321:     for(itimes=1;itimes<=2;itimes++){
                   12322:       jj=0;
                   12323:       for(i=1; i <=nlstate; i++){
1.225     brouard  12324:        for(j=1; j <=nlstate+ndeath; j++){
                   12325:          if(j==i) continue;
                   12326:          for(k=1; k<=ncovmodel;k++){
                   12327:            jj++;
                   12328:            ca[0]= k+'a'-1;ca[1]='\0';
                   12329:            if(itimes==1){
                   12330:              if(mle>=1)
                   12331:                printf("#%1d%1d%d",i,j,k);
                   12332:              fprintf(ficlog,"#%1d%1d%d",i,j,k);
                   12333:              fprintf(ficres,"#%1d%1d%d",i,j,k);
                   12334:            }else{
                   12335:              if(mle>=1)
                   12336:                printf("%1d%1d%d",i,j,k);
                   12337:              fprintf(ficlog,"%1d%1d%d",i,j,k);
                   12338:              fprintf(ficres,"%1d%1d%d",i,j,k);
                   12339:            }
                   12340:            ll=0;
                   12341:            for(li=1;li <=nlstate; li++){
                   12342:              for(lj=1;lj <=nlstate+ndeath; lj++){
                   12343:                if(lj==li) continue;
                   12344:                for(lk=1;lk<=ncovmodel;lk++){
                   12345:                  ll++;
                   12346:                  if(ll<=jj){
                   12347:                    cb[0]= lk +'a'-1;cb[1]='\0';
                   12348:                    if(ll<jj){
                   12349:                      if(itimes==1){
                   12350:                        if(mle>=1)
                   12351:                          printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12352:                        fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12353:                        fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                   12354:                      }else{
                   12355:                        if(mle>=1)
                   12356:                          printf(" %.5e",matcov[jj][ll]); 
                   12357:                        fprintf(ficlog," %.5e",matcov[jj][ll]); 
                   12358:                        fprintf(ficres," %.5e",matcov[jj][ll]); 
                   12359:                      }
                   12360:                    }else{
                   12361:                      if(itimes==1){
                   12362:                        if(mle>=1)
                   12363:                          printf(" Var(%s%1d%1d)",ca,i,j);
                   12364:                        fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                   12365:                        fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                   12366:                      }else{
                   12367:                        if(mle>=1)
                   12368:                          printf(" %.7e",matcov[jj][ll]); 
                   12369:                        fprintf(ficlog," %.7e",matcov[jj][ll]); 
                   12370:                        fprintf(ficres," %.7e",matcov[jj][ll]); 
                   12371:                      }
                   12372:                    }
                   12373:                  }
                   12374:                } /* end lk */
                   12375:              } /* end lj */
                   12376:            } /* end li */
                   12377:            if(mle>=1)
                   12378:              printf("\n");
                   12379:            fprintf(ficlog,"\n");
                   12380:            fprintf(ficres,"\n");
                   12381:            numlinepar++;
                   12382:          } /* end k*/
                   12383:        } /*end j */
1.126     brouard  12384:       } /* end i */
                   12385:     } /* end itimes */
                   12386:     
                   12387:     fflush(ficlog);
                   12388:     fflush(ficres);
1.225     brouard  12389:     while(fgets(line, MAXLINE, ficpar)) {
                   12390:       /* If line starts with a # it is a comment */
                   12391:       if (line[0] == '#') {
                   12392:        numlinepar++;
                   12393:        fputs(line,stdout);
                   12394:        fputs(line,ficparo);
                   12395:        fputs(line,ficlog);
1.299     brouard  12396:        fputs(line,ficres);
1.225     brouard  12397:        continue;
                   12398:       }else
                   12399:        break;
                   12400:     }
                   12401:     
1.209     brouard  12402:     /* while((c=getc(ficpar))=='#' && c!= EOF){ */
                   12403:     /*   ungetc(c,ficpar); */
                   12404:     /*   fgets(line, MAXLINE, ficpar); */
                   12405:     /*   fputs(line,stdout); */
                   12406:     /*   fputs(line,ficparo); */
                   12407:     /* } */
                   12408:     /* ungetc(c,ficpar); */
1.126     brouard  12409:     
                   12410:     estepm=0;
1.209     brouard  12411:     if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
1.225     brouard  12412:       
                   12413:       if (num_filled != 6) {
                   12414:        printf("Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12415:        fprintf(ficlog,"Error: Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n, your line=%s . Probably you are running an older format.\n",line);
                   12416:        goto end;
                   12417:       }
                   12418:       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
                   12419:     }
                   12420:     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
                   12421:     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
                   12422:     
1.209     brouard  12423:     /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
1.126     brouard  12424:     if (estepm==0 || estepm < stepm) estepm=stepm;
                   12425:     if (fage <= 2) {
                   12426:       bage = ageminpar;
                   12427:       fage = agemaxpar;
                   12428:     }
                   12429:     
                   12430:     fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
1.211     brouard  12431:     fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
                   12432:     fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d, ftolpl=%e\n",ageminpar,agemaxpar,bage,fage, estepm, ftolpl);
1.220     brouard  12433:                
1.186     brouard  12434:     /* Other stuffs, more or less useful */    
1.254     brouard  12435:     while(fgets(line, MAXLINE, ficpar)) {
                   12436:       /* If line starts with a # it is a comment */
                   12437:       if (line[0] == '#') {
                   12438:        numlinepar++;
                   12439:        fputs(line,stdout);
                   12440:        fputs(line,ficparo);
                   12441:        fputs(line,ficlog);
1.299     brouard  12442:        fputs(line,ficres);
1.254     brouard  12443:        continue;
                   12444:       }else
                   12445:        break;
                   12446:     }
                   12447: 
                   12448:     if((num_filled=sscanf(line,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav)) !=EOF){
                   12449:       
                   12450:       if (num_filled != 7) {
                   12451:        printf("Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12452:        fprintf(ficlog,"Error: Not 7 (data)parameters in line but %d, for example:begin-prev-date=1/1/1990 end-prev-date=1/6/2004  mov_average=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12453:        goto end;
                   12454:       }
                   12455:       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12456:       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12457:       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
                   12458:       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
1.126     brouard  12459:     }
1.254     brouard  12460: 
                   12461:     while(fgets(line, MAXLINE, ficpar)) {
                   12462:       /* If line starts with a # it is a comment */
                   12463:       if (line[0] == '#') {
                   12464:        numlinepar++;
                   12465:        fputs(line,stdout);
                   12466:        fputs(line,ficparo);
                   12467:        fputs(line,ficlog);
1.299     brouard  12468:        fputs(line,ficres);
1.254     brouard  12469:        continue;
                   12470:       }else
                   12471:        break;
1.126     brouard  12472:     }
                   12473:     
                   12474:     
                   12475:     dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
                   12476:     dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
                   12477:     
1.254     brouard  12478:     if((num_filled=sscanf(line,"pop_based=%d\n",&popbased)) !=EOF){
                   12479:       if (num_filled != 1) {
                   12480:        printf("Error: Not 1 (data)parameters in line but %d, for example:pop_based=0\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12481:        fprintf(ficlog,"Error: Not 1 (data)parameters in line but %d, for example: pop_based=1\n, your line=%s . Probably you are running an older format.\n",num_filled,line);
                   12482:        goto end;
                   12483:       }
                   12484:       printf("pop_based=%d\n",popbased);
                   12485:       fprintf(ficlog,"pop_based=%d\n",popbased);
                   12486:       fprintf(ficparo,"pop_based=%d\n",popbased);   
                   12487:       fprintf(ficres,"pop_based=%d\n",popbased);   
                   12488:     }
                   12489:      
1.258     brouard  12490:     /* Results */
1.307     brouard  12491:     endishere=0;
1.258     brouard  12492:     nresult=0;
1.308     brouard  12493:     parameterline=0;
1.258     brouard  12494:     do{
                   12495:       if(!fgets(line, MAXLINE, ficpar)){
                   12496:        endishere=1;
1.308     brouard  12497:        parameterline=15;
1.258     brouard  12498:       }else if (line[0] == '#') {
                   12499:        /* If line starts with a # it is a comment */
1.254     brouard  12500:        numlinepar++;
                   12501:        fputs(line,stdout);
                   12502:        fputs(line,ficparo);
                   12503:        fputs(line,ficlog);
1.299     brouard  12504:        fputs(line,ficres);
1.254     brouard  12505:        continue;
1.258     brouard  12506:       }else if(sscanf(line,"prevforecast=%[^\n]\n",modeltemp))
                   12507:        parameterline=11;
1.296     brouard  12508:       else if(sscanf(line,"prevbackcast=%[^\n]\n",modeltemp))
1.258     brouard  12509:        parameterline=12;
1.307     brouard  12510:       else if(sscanf(line,"result:%[^\n]\n",modeltemp)){
1.258     brouard  12511:        parameterline=13;
1.307     brouard  12512:       }
1.258     brouard  12513:       else{
                   12514:        parameterline=14;
1.254     brouard  12515:       }
1.308     brouard  12516:       switch (parameterline){ /* =0 only if only comments */
1.258     brouard  12517:       case 11:
1.296     brouard  12518:        if((num_filled=sscanf(line,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12519:                  fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
1.258     brouard  12520:          printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12521:          fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12522:          fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
                   12523:          /* day and month of proj2 are not used but only year anproj2.*/
1.273     brouard  12524:          dateproj1=anproj1+(mproj1-1)/12.+(jproj1-1)/365.;
                   12525:          dateproj2=anproj2+(mproj2-1)/12.+(jproj2-1)/365.;
1.296     brouard  12526:           prvforecast = 1;
                   12527:        } 
                   12528:        else if((num_filled=sscanf(line,"prevforecast=%d yearsfproj=%lf mobil_average=%d\n",&prevfcast,&yrfproj,&mobilavproj)) !=EOF){/* && (num_filled == 3))*/
1.313     brouard  12529:          printf("prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12530:          fprintf(ficlog,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
                   12531:          fprintf(ficres,"prevforecast=%d yearsfproj=%.2lf mobil_average=%d\n",prevfcast,yrfproj,mobilavproj);
1.296     brouard  12532:           prvforecast = 2;
                   12533:        }
                   12534:        else {
                   12535:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearsfproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12536:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevforecast=1 starting-proj-date=1/1/1990 final-proj-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevforecast=1 yearproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12537:          goto end;
1.258     brouard  12538:        }
1.254     brouard  12539:        break;
1.258     brouard  12540:       case 12:
1.296     brouard  12541:        if((num_filled=sscanf(line,"prevbackcast=%d starting-back-date=%lf/%lf/%lf final-back-date=%lf/%lf/%lf mobil_average=%d\n",&prevbcast,&jback1,&mback1,&anback1,&jback2,&mback2,&anback2,&mobilavproj)) !=EOF && (num_filled == 8)){
                   12542:           fprintf(ficparo,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12543:          printf("prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12544:          fprintf(ficlog,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12545:          fprintf(ficres,"prevbackcast=%d starting-back-date=%.lf/%.lf/%.lf final-back-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevbcast,jback1,mback1,anback1,jback2,mback2,anback2,mobilavproj);
                   12546:          /* day and month of back2 are not used but only year anback2.*/
1.273     brouard  12547:          dateback1=anback1+(mback1-1)/12.+(jback1-1)/365.;
                   12548:          dateback2=anback2+(mback2-1)/12.+(jback2-1)/365.;
1.296     brouard  12549:           prvbackcast = 1;
                   12550:        } 
                   12551:        else if((num_filled=sscanf(line,"prevbackcast=%d yearsbproj=%lf mobil_average=%d\n",&prevbcast,&yrbproj,&mobilavproj)) ==3){/* && (num_filled == 3))*/
1.313     brouard  12552:          printf("prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12553:          fprintf(ficlog,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
                   12554:          fprintf(ficres,"prevbackcast=%d yearsbproj=%.2lf mobil_average=%d\n",prevbcast,yrbproj,mobilavproj);
1.296     brouard  12555:           prvbackcast = 2;
                   12556:        }
                   12557:        else {
                   12558:          printf("Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearsbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12559:          fprintf(ficlog,"Error: Not 8 (data)parameters in line but %d, for example:prevbackcast=1 starting-back-date=1/1/1990 final-back-date=1/1/2000 mobil_average=0\nnor 3 (data)parameters, for example:prevbackcast=1 yearbproj=10 mobil_average=0. Your line=%s . You are running probably an older format.\n, ",num_filled,line);
                   12560:          goto end;
1.258     brouard  12561:        }
1.230     brouard  12562:        break;
1.258     brouard  12563:       case 13:
1.307     brouard  12564:        num_filled=sscanf(line,"result:%[^\n]\n",resultline);
                   12565:        nresult++; /* Sum of resultlines */
                   12566:        printf("Result %d: result:%s\n",nresult, resultline);
                   12567:        if(nresult > MAXRESULTLINES){
                   12568:          printf("ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINES,nresult,rfileres);
                   12569:          fprintf(ficlog,"ERROR: Current version of IMaCh limits the number of resultlines to %d, you used %d\nYou can use the 'r' parameter file '%s' which uses option mle=0 to get other results. ",MAXRESULTLINES,nresult,rfileres);
                   12570:          goto end;
                   12571:        }
1.310     brouard  12572:        if(!decoderesult(resultline, nresult)){ /* Fills TKresult[nresult] combination and Tresult[nresult][k4+1] combination values */
1.314     brouard  12573:          fprintf(ficparo,"result: %s\n",resultline);
                   12574:          fprintf(ficres,"result: %s\n",resultline);
                   12575:          fprintf(ficlog,"result: %s\n",resultline);
1.310     brouard  12576:        } else
                   12577:          goto end;
1.307     brouard  12578:        break;
                   12579:       case 14:
                   12580:        printf("Error: Unknown command '%s'\n",line);
                   12581:        fprintf(ficlog,"Error: Unknown command '%s'\n",line);
1.314     brouard  12582:        if(line[0] == ' ' || line[0] == '\n'){
                   12583:          printf("It should not be an empty line '%s'\n",line);
                   12584:          fprintf(ficlog,"It should not be an empty line '%s'\n",line);
                   12585:        }         
1.307     brouard  12586:        if(ncovmodel >=2 && nresult==0 ){
                   12587:          printf("ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
                   12588:          fprintf(ficlog,"ERROR: no result lines! It should be at minimum 'result: V2=0 V1=1 or result:.' %s\n",line);
1.258     brouard  12589:        }
1.307     brouard  12590:        /* goto end; */
                   12591:        break;
1.308     brouard  12592:       case 15:
                   12593:        printf("End of resultlines.\n");
                   12594:        fprintf(ficlog,"End of resultlines.\n");
                   12595:        break;
                   12596:       default: /* parameterline =0 */
1.307     brouard  12597:        nresult=1;
                   12598:        decoderesult(".",nresult ); /* No covariate */
1.258     brouard  12599:       } /* End switch parameterline */
                   12600:     }while(endishere==0); /* End do */
1.126     brouard  12601:     
1.230     brouard  12602:     /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
1.145     brouard  12603:     /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
1.126     brouard  12604:     
                   12605:     replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
1.194     brouard  12606:     if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
1.230     brouard  12607:       printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12608: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12609: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.230     brouard  12610:       fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
1.194     brouard  12611: This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
                   12612: Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
1.220     brouard  12613:     }else{
1.270     brouard  12614:       /* printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, prevfcast, backcast, pathc,p, (int)anproj1-(int)agemin, (int)anback1-(int)agemax+1); */
1.296     brouard  12615:       /* It seems that anprojd which is computed from the mean year at interview which is known yet because of freqsummary */
                   12616:       /* date2dmy(dateintmean,&jintmean,&mintmean,&aintmean); */ /* Done in freqsummary */
                   12617:       if(prvforecast==1){
                   12618:         dateprojd=(jproj1+12*mproj1+365*anproj1)/365;
                   12619:         jprojd=jproj1;
                   12620:         mprojd=mproj1;
                   12621:         anprojd=anproj1;
                   12622:         dateprojf=(jproj2+12*mproj2+365*anproj2)/365;
                   12623:         jprojf=jproj2;
                   12624:         mprojf=mproj2;
                   12625:         anprojf=anproj2;
                   12626:       } else if(prvforecast == 2){
                   12627:         dateprojd=dateintmean;
                   12628:         date2dmy(dateprojd,&jprojd, &mprojd, &anprojd);
                   12629:         dateprojf=dateintmean+yrfproj;
                   12630:         date2dmy(dateprojf,&jprojf, &mprojf, &anprojf);
                   12631:       }
                   12632:       if(prvbackcast==1){
                   12633:         datebackd=(jback1+12*mback1+365*anback1)/365;
                   12634:         jbackd=jback1;
                   12635:         mbackd=mback1;
                   12636:         anbackd=anback1;
                   12637:         datebackf=(jback2+12*mback2+365*anback2)/365;
                   12638:         jbackf=jback2;
                   12639:         mbackf=mback2;
                   12640:         anbackf=anback2;
                   12641:       } else if(prvbackcast == 2){
                   12642:         datebackd=dateintmean;
                   12643:         date2dmy(datebackd,&jbackd, &mbackd, &anbackd);
                   12644:         datebackf=dateintmean-yrbproj;
                   12645:         date2dmy(datebackf,&jbackf, &mbackf, &anbackf);
                   12646:       }
                   12647:       
                   12648:       printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,bage, fage, prevfcast, prevbcast, pathc,p, (int)anprojd-bage, (int)anbackd-fage);
1.220     brouard  12649:     }
                   12650:     printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt, \
1.296     brouard  12651:                 model,imx,jmin,jmax,jmean,rfileres,popforecast,mobilav,prevfcast,mobilavproj,prevbcast, estepm, \
                   12652:                 jprev1,mprev1,anprev1,dateprev1, dateprojd, datebackd,jprev2,mprev2,anprev2,dateprev2,dateprojf, datebackf);
1.220     brouard  12653:                
1.225     brouard  12654:     /*------------ free_vector  -------------*/
                   12655:     /*  chdir(path); */
1.220     brouard  12656:                
1.215     brouard  12657:     /* free_ivector(wav,1,imx); */  /* Moved after last prevalence call */
                   12658:     /* free_imatrix(dh,1,lastpass-firstpass+2,1,imx); */
                   12659:     /* free_imatrix(bh,1,lastpass-firstpass+2,1,imx); */
                   12660:     /* free_imatrix(mw,1,lastpass-firstpass+2,1,imx);    */
1.290     brouard  12661:     free_lvector(num,firstobs,lastobs);
                   12662:     free_vector(agedc,firstobs,lastobs);
1.126     brouard  12663:     /*free_matrix(covar,0,NCOVMAX,1,n);*/
                   12664:     /*free_matrix(covar,1,NCOVMAX,1,n);*/
                   12665:     fclose(ficparo);
                   12666:     fclose(ficres);
1.220     brouard  12667:                
                   12668:                
1.186     brouard  12669:     /* Other results (useful)*/
1.220     brouard  12670:                
                   12671:                
1.126     brouard  12672:     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
1.180     brouard  12673:     /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
                   12674:     prlim=matrix(1,nlstate,1,nlstate);
1.209     brouard  12675:     prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
1.126     brouard  12676:     fclose(ficrespl);
                   12677: 
                   12678:     /*------------- h Pij x at various ages ------------*/
1.180     brouard  12679:     /*#include "hpijx.h"*/
                   12680:     hPijx(p, bage, fage);
1.145     brouard  12681:     fclose(ficrespij);
1.227     brouard  12682:     
1.220     brouard  12683:     /* ncovcombmax=  pow(2,cptcoveff); */
1.219     brouard  12684:     /*-------------- Variance of one-step probabilities---*/
1.145     brouard  12685:     k=1;
1.126     brouard  12686:     varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
1.227     brouard  12687:     
1.269     brouard  12688:     /* Prevalence for each covariate combination in probs[age][status][cov] */
                   12689:     probs= ma3x(AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12690:     for(i=AGEINF;i<=AGESUP;i++)
1.219     brouard  12691:       for(j=1;j<=nlstate+ndeath;j++) /* ndeath is useless but a necessity to be compared with mobaverages */
1.225     brouard  12692:        for(k=1;k<=ncovcombmax;k++)
                   12693:          probs[i][j][k]=0.;
1.269     brouard  12694:     prevalence(probs, ageminpar, agemaxpar, s, agev, nlstate, imx, Tvar, nbcode, 
                   12695:               ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
1.219     brouard  12696:     if (mobilav!=0 ||mobilavproj !=0 ) {
1.269     brouard  12697:       mobaverages= ma3x(AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
                   12698:       for(i=AGEINF;i<=AGESUP;i++)
1.268     brouard  12699:        for(j=1;j<=nlstate+ndeath;j++)
1.227     brouard  12700:          for(k=1;k<=ncovcombmax;k++)
                   12701:            mobaverages[i][j][k]=0.;
1.219     brouard  12702:       mobaverage=mobaverages;
                   12703:       if (mobilav!=0) {
1.235     brouard  12704:        printf("Movingaveraging observed prevalence\n");
1.258     brouard  12705:        fprintf(ficlog,"Movingaveraging observed prevalence\n");
1.227     brouard  12706:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilav)!=0){
                   12707:          fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
                   12708:          printf(" Error in movingaverage mobilav=%d\n",mobilav);
                   12709:        }
1.269     brouard  12710:       } else if (mobilavproj !=0) {
1.235     brouard  12711:        printf("Movingaveraging projected observed prevalence\n");
1.258     brouard  12712:        fprintf(ficlog,"Movingaveraging projected observed prevalence\n");
1.227     brouard  12713:        if (movingaverage(probs, ageminpar, agemaxpar, mobaverage, mobilavproj)!=0){
                   12714:          fprintf(ficlog," Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12715:          printf(" Error in movingaverage mobilavproj=%d\n",mobilavproj);
                   12716:        }
1.269     brouard  12717:       }else{
                   12718:        printf("Internal error moving average\n");
                   12719:        fflush(stdout);
                   12720:        exit(1);
1.219     brouard  12721:       }
                   12722:     }/* end if moving average */
1.227     brouard  12723:     
1.126     brouard  12724:     /*---------- Forecasting ------------------*/
1.296     brouard  12725:     if(prevfcast==1){ 
                   12726:       /*   /\*    if(stepm ==1){*\/ */
                   12727:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12728:       /*This done previously after freqsummary.*/
                   12729:       /*   dateprojd=(jproj1+12*mproj1+365*anproj1)/365; */
                   12730:       /*   dateprojf=(jproj2+12*mproj2+365*anproj2)/365; */
                   12731:       
                   12732:       /* } else if (prvforecast==2){ */
                   12733:       /*   /\*    if(stepm ==1){*\/ */
                   12734:       /*   /\*  anproj1, mproj1, jproj1 either read explicitly or yrfproj *\/ */
                   12735:       /* } */
                   12736:       /*prevforecast(fileresu, dateintmean, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);*/
                   12737:       prevforecast(fileresu,dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2, mobilavproj, mobaverage, bage, fage, firstpass, lastpass, p, cptcoveff);
1.126     brouard  12738:     }
1.269     brouard  12739: 
1.296     brouard  12740:     /* Prevbcasting */
                   12741:     if(prevbcast==1){
1.219     brouard  12742:       ddnewms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12743:       ddoldms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);       
                   12744:       ddsavms=matrix(1,nlstate+ndeath,1,nlstate+ndeath);
                   12745: 
                   12746:       /*--------------- Back Prevalence limit  (period or stable prevalence) --------------*/
                   12747: 
                   12748:       bprlim=matrix(1,nlstate,1,nlstate);
1.269     brouard  12749: 
1.219     brouard  12750:       back_prevalence_limit(p, bprlim,  ageminpar, agemaxpar, ftolpl, &ncvyear, dateprev1, dateprev2, firstpass, lastpass, mobilavproj);
                   12751:       fclose(ficresplb);
                   12752: 
1.222     brouard  12753:       hBijx(p, bage, fage, mobaverage);
                   12754:       fclose(ficrespijb);
1.219     brouard  12755: 
1.296     brouard  12756:       /* /\* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, *\/ */
                   12757:       /* /\*                  mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); *\/ */
                   12758:       /* prevbackforecast(fileresu, mobaverage, anback1, mback1, jback1, agemin, agemax, dateprev1, dateprev2, */
                   12759:       /*                      mobilavproj, bage, fage, firstpass, lastpass, anback2, p, cptcoveff); */
                   12760:       prevbackforecast(fileresu, mobaverage, dateintmean, dateprojd, dateprojf, agemin, agemax, dateprev1, dateprev2,
                   12761:                       mobilavproj, bage, fage, firstpass, lastpass, p, cptcoveff);
                   12762: 
                   12763:       
1.269     brouard  12764:       varbprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, bprlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12765: 
                   12766:       
1.269     brouard  12767:       free_matrix(bprlim,1,nlstate,1,nlstate); /*here or after loop ? */
1.219     brouard  12768:       free_matrix(ddnewms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12769:       free_matrix(ddsavms, 1, nlstate+ndeath, 1, nlstate+ndeath);
                   12770:       free_matrix(ddoldms, 1, nlstate+ndeath, 1, nlstate+ndeath);
1.296     brouard  12771:     }    /* end  Prevbcasting */
1.268     brouard  12772:  
1.186     brouard  12773:  
                   12774:     /* ------ Other prevalence ratios------------ */
1.126     brouard  12775: 
1.215     brouard  12776:     free_ivector(wav,1,imx);
                   12777:     free_imatrix(dh,1,lastpass-firstpass+2,1,imx);
                   12778:     free_imatrix(bh,1,lastpass-firstpass+2,1,imx);
                   12779:     free_imatrix(mw,1,lastpass-firstpass+2,1,imx);   
1.218     brouard  12780:                
                   12781:                
1.127     brouard  12782:     /*---------- Health expectancies, no variances ------------*/
1.218     brouard  12783:                
1.201     brouard  12784:     strcpy(filerese,"E_");
                   12785:     strcat(filerese,fileresu);
1.126     brouard  12786:     if((ficreseij=fopen(filerese,"w"))==NULL) {
                   12787:       printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12788:       fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
                   12789:     }
1.208     brouard  12790:     printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
                   12791:     fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
1.238     brouard  12792: 
                   12793:     pstamp(ficreseij);
1.219     brouard  12794:                
1.235     brouard  12795:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12796:     if (cptcovn < 1){i1=1;}
                   12797:     
                   12798:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12799:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12800:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12801:        continue;
1.219     brouard  12802:       fprintf(ficreseij,"\n#****** ");
1.235     brouard  12803:       printf("\n#****** ");
1.225     brouard  12804:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12805:        fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12806:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12807:       }
                   12808:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12809:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12810:        fprintf(ficreseij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
1.219     brouard  12811:       }
                   12812:       fprintf(ficreseij,"******\n");
1.235     brouard  12813:       printf("******\n");
1.219     brouard  12814:       
                   12815:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12816:       oldm=oldms;savm=savms;
1.235     brouard  12817:       evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart, nres);  
1.127     brouard  12818:       
1.219     brouard  12819:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.127     brouard  12820:     }
                   12821:     fclose(ficreseij);
1.208     brouard  12822:     printf("done evsij\n");fflush(stdout);
                   12823:     fprintf(ficlog,"done evsij\n");fflush(ficlog);
1.269     brouard  12824: 
1.218     brouard  12825:                
1.227     brouard  12826:     /*---------- State-specific expectancies and variances ------------*/
1.218     brouard  12827:                
1.201     brouard  12828:     strcpy(filerest,"T_");
                   12829:     strcat(filerest,fileresu);
1.127     brouard  12830:     if((ficrest=fopen(filerest,"w"))==NULL) {
                   12831:       printf("Problem with total LE resultfile: %s\n", filerest);goto end;
                   12832:       fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
                   12833:     }
1.208     brouard  12834:     printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
                   12835:     fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
1.201     brouard  12836:     strcpy(fileresstde,"STDE_");
                   12837:     strcat(fileresstde,fileresu);
1.126     brouard  12838:     if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
1.227     brouard  12839:       printf("Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
                   12840:       fprintf(ficlog,"Problem with State specific Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
1.126     brouard  12841:     }
1.227     brouard  12842:     printf("  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
                   12843:     fprintf(ficlog,"  Computing State-specific Expectancies and standard errors: result on file '%s' \n", fileresstde);
1.126     brouard  12844: 
1.201     brouard  12845:     strcpy(filerescve,"CVE_");
                   12846:     strcat(filerescve,fileresu);
1.126     brouard  12847:     if((ficrescveij=fopen(filerescve,"w"))==NULL) {
1.227     brouard  12848:       printf("Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
                   12849:       fprintf(ficlog,"Problem with Covar. State-specific Exp. resultfile: %s\n", filerescve); exit(0);
1.126     brouard  12850:     }
1.227     brouard  12851:     printf("    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
                   12852:     fprintf(ficlog,"    Computing Covar. of State-specific Expectancies: result on file '%s' \n", filerescve);
1.126     brouard  12853: 
1.201     brouard  12854:     strcpy(fileresv,"V_");
                   12855:     strcat(fileresv,fileresu);
1.126     brouard  12856:     if((ficresvij=fopen(fileresv,"w"))==NULL) {
                   12857:       printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12858:       fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
                   12859:     }
1.227     brouard  12860:     printf("      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(stdout);
                   12861:     fprintf(ficlog,"      Computing Variance-covariance of State-specific Expectancies: file '%s' ... ", fileresv);fflush(ficlog);
1.126     brouard  12862: 
1.235     brouard  12863:     i1=pow(2,cptcoveff); /* Number of combination of dummy covariates */
                   12864:     if (cptcovn < 1){i1=1;}
                   12865:     
                   12866:     for(nres=1; nres <= nresult; nres++) /* For each resultline */
                   12867:     for(k=1; k<=i1;k++){ /* For any combination of dummy covariates, fixed and varying */
1.253     brouard  12868:       if(i1 != 1 && TKresult[nres]!= k)
1.235     brouard  12869:        continue;
1.242     brouard  12870:       printf("\n#****** Result for:");
                   12871:       fprintf(ficrest,"\n#****** Result for:");
                   12872:       fprintf(ficlog,"\n#****** Result for:");
1.227     brouard  12873:       for(j=1;j<=cptcoveff;j++){ 
                   12874:        printf("V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12875:        fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12876:        fprintf(ficlog,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12877:       }
1.235     brouard  12878:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12879:        printf(" V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12880:        fprintf(ficrest," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12881:        fprintf(ficlog," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12882:       }        
1.208     brouard  12883:       fprintf(ficrest,"******\n");
1.227     brouard  12884:       fprintf(ficlog,"******\n");
                   12885:       printf("******\n");
1.208     brouard  12886:       
                   12887:       fprintf(ficresstdeij,"\n#****** ");
                   12888:       fprintf(ficrescveij,"\n#****** ");
1.225     brouard  12889:       for(j=1;j<=cptcoveff;j++) {
1.227     brouard  12890:        fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                   12891:        fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.208     brouard  12892:       }
1.235     brouard  12893:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12894:        fprintf(ficresstdeij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12895:        fprintf(ficrescveij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12896:       }        
1.208     brouard  12897:       fprintf(ficresstdeij,"******\n");
                   12898:       fprintf(ficrescveij,"******\n");
                   12899:       
                   12900:       fprintf(ficresvij,"\n#****** ");
1.238     brouard  12901:       /* pstamp(ficresvij); */
1.225     brouard  12902:       for(j=1;j<=cptcoveff;j++) 
1.227     brouard  12903:        fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
1.235     brouard  12904:       for (j=1; j<= nsq; j++){ /* For each selected (single) quantitative value */
                   12905:        fprintf(ficresvij," V%d=%f ",Tvqresult[nres][j],Tqresult[nres][j]);
                   12906:       }        
1.208     brouard  12907:       fprintf(ficresvij,"******\n");
                   12908:       
                   12909:       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12910:       oldm=oldms;savm=savms;
1.235     brouard  12911:       printf(" cvevsij ");
                   12912:       fprintf(ficlog, " cvevsij ");
                   12913:       cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart, nres);
1.208     brouard  12914:       printf(" end cvevsij \n ");
                   12915:       fprintf(ficlog, " end cvevsij \n ");
                   12916:       
                   12917:       /*
                   12918:        */
                   12919:       /* goto endfree; */
                   12920:       
                   12921:       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
                   12922:       pstamp(ficrest);
                   12923:       
1.269     brouard  12924:       epj=vector(1,nlstate+1);
1.208     brouard  12925:       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
1.227     brouard  12926:        oldm=oldms;savm=savms; /* ZZ Segmentation fault */
                   12927:        cptcod= 0; /* To be deleted */
                   12928:        printf("varevsij vpopbased=%d \n",vpopbased);
                   12929:        fprintf(ficlog, "varevsij vpopbased=%d \n",vpopbased);
1.235     brouard  12930:        varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart, nres); /* cptcod not initialized Intel */
1.227     brouard  12931:        fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
                   12932:        if(vpopbased==1)
                   12933:          fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
                   12934:        else
1.288     brouard  12935:          fprintf(ficrest,"the age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12936:        fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
                   12937:        for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
                   12938:        fprintf(ficrest,"\n");
                   12939:        /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
1.288     brouard  12940:        printf("Computing age specific forward period (stable) prevalences in each health state \n");
                   12941:        fprintf(ficlog,"Computing age specific forward period (stable) prevalences in each health state \n");
1.227     brouard  12942:        for(age=bage; age <=fage ;age++){
1.235     brouard  12943:          prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k, nres); /*ZZ Is it the correct prevalim */
1.227     brouard  12944:          if (vpopbased==1) {
                   12945:            if(mobilav ==0){
                   12946:              for(i=1; i<=nlstate;i++)
                   12947:                prlim[i][i]=probs[(int)age][i][k];
                   12948:            }else{ /* mobilav */ 
                   12949:              for(i=1; i<=nlstate;i++)
                   12950:                prlim[i][i]=mobaverage[(int)age][i][k];
                   12951:            }
                   12952:          }
1.219     brouard  12953:          
1.227     brouard  12954:          fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
                   12955:          /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
                   12956:          /* printf(" age %4.0f ",age); */
                   12957:          for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
                   12958:            for(i=1, epj[j]=0.;i <=nlstate;i++) {
                   12959:              epj[j] += prlim[i][i]*eij[i][j][(int)age];
                   12960:              /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                   12961:              /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
                   12962:            }
                   12963:            epj[nlstate+1] +=epj[j];
                   12964:          }
                   12965:          /* printf(" age %4.0f \n",age); */
1.219     brouard  12966:          
1.227     brouard  12967:          for(i=1, vepp=0.;i <=nlstate;i++)
                   12968:            for(j=1;j <=nlstate;j++)
                   12969:              vepp += vareij[i][j][(int)age];
                   12970:          fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
                   12971:          for(j=1;j <=nlstate;j++){
                   12972:            fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
                   12973:          }
                   12974:          fprintf(ficrest,"\n");
                   12975:        }
1.208     brouard  12976:       } /* End vpopbased */
1.269     brouard  12977:       free_vector(epj,1,nlstate+1);
1.208     brouard  12978:       free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
                   12979:       free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
1.235     brouard  12980:       printf("done selection\n");fflush(stdout);
                   12981:       fprintf(ficlog,"done selection\n");fflush(ficlog);
1.208     brouard  12982:       
1.235     brouard  12983:     } /* End k selection */
1.227     brouard  12984: 
                   12985:     printf("done State-specific expectancies\n");fflush(stdout);
                   12986:     fprintf(ficlog,"done State-specific expectancies\n");fflush(ficlog);
                   12987: 
1.288     brouard  12988:     /* variance-covariance of forward period prevalence*/
1.269     brouard  12989:     varprlim(fileresu, nresult, mobaverage, mobilavproj, bage, fage, prlim, &ncvyear, ftolpl, p, matcov, delti, stepm, cptcoveff);
1.268     brouard  12990: 
1.227     brouard  12991:     
1.290     brouard  12992:     free_vector(weight,firstobs,lastobs);
1.227     brouard  12993:     free_imatrix(Tvard,1,NCOVMAX,1,2);
1.290     brouard  12994:     free_imatrix(s,1,maxwav+1,firstobs,lastobs);
                   12995:     free_matrix(anint,1,maxwav,firstobs,lastobs); 
                   12996:     free_matrix(mint,1,maxwav,firstobs,lastobs);
                   12997:     free_ivector(cod,firstobs,lastobs);
1.227     brouard  12998:     free_ivector(tab,1,NCOVMAX);
                   12999:     fclose(ficresstdeij);
                   13000:     fclose(ficrescveij);
                   13001:     fclose(ficresvij);
                   13002:     fclose(ficrest);
                   13003:     fclose(ficpar);
                   13004:     
                   13005:     
1.126     brouard  13006:     /*---------- End : free ----------------*/
1.219     brouard  13007:     if (mobilav!=0 ||mobilavproj !=0)
1.269     brouard  13008:       free_ma3x(mobaverages,AGEINF, AGESUP,1,nlstate+ndeath, 1,ncovcombmax); /* We need to have a squared matrix with prevalence of the dead! */
                   13009:     free_ma3x(probs,AGEINF,AGESUP,1,nlstate+ndeath, 1,ncovcombmax);
1.220     brouard  13010:     free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
                   13011:     free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
1.126     brouard  13012:   }  /* mle==-3 arrives here for freeing */
1.227     brouard  13013:   /* endfree:*/
                   13014:   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   13015:   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
                   13016:   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
1.290     brouard  13017:   if(ntv+nqtv>=1)free_ma3x(cotvar,1,maxwav,1,ntv+nqtv,firstobs,lastobs);
                   13018:   if(nqtv>=1)free_ma3x(cotqvar,1,maxwav,1,nqtv,firstobs,lastobs);
                   13019:   if(nqv>=1)free_matrix(coqvar,1,nqv,firstobs,lastobs);
                   13020:   free_matrix(covar,0,NCOVMAX,firstobs,lastobs);
1.227     brouard  13021:   free_matrix(matcov,1,npar,1,npar);
                   13022:   free_matrix(hess,1,npar,1,npar);
                   13023:   /*free_vector(delti,1,npar);*/
                   13024:   free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
                   13025:   free_matrix(agev,1,maxwav,1,imx);
1.269     brouard  13026:   free_ma3x(paramstart,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
1.227     brouard  13027:   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
                   13028:   
                   13029:   free_ivector(ncodemax,1,NCOVMAX);
                   13030:   free_ivector(ncodemaxwundef,1,NCOVMAX);
                   13031:   free_ivector(Dummy,-1,NCOVMAX);
                   13032:   free_ivector(Fixed,-1,NCOVMAX);
1.238     brouard  13033:   free_ivector(DummyV,1,NCOVMAX);
                   13034:   free_ivector(FixedV,1,NCOVMAX);
1.227     brouard  13035:   free_ivector(Typevar,-1,NCOVMAX);
                   13036:   free_ivector(Tvar,1,NCOVMAX);
1.234     brouard  13037:   free_ivector(TvarsQ,1,NCOVMAX);
                   13038:   free_ivector(TvarsQind,1,NCOVMAX);
                   13039:   free_ivector(TvarsD,1,NCOVMAX);
                   13040:   free_ivector(TvarsDind,1,NCOVMAX);
1.231     brouard  13041:   free_ivector(TvarFD,1,NCOVMAX);
                   13042:   free_ivector(TvarFDind,1,NCOVMAX);
1.232     brouard  13043:   free_ivector(TvarF,1,NCOVMAX);
                   13044:   free_ivector(TvarFind,1,NCOVMAX);
                   13045:   free_ivector(TvarV,1,NCOVMAX);
                   13046:   free_ivector(TvarVind,1,NCOVMAX);
                   13047:   free_ivector(TvarA,1,NCOVMAX);
                   13048:   free_ivector(TvarAind,1,NCOVMAX);
1.231     brouard  13049:   free_ivector(TvarFQ,1,NCOVMAX);
                   13050:   free_ivector(TvarFQind,1,NCOVMAX);
                   13051:   free_ivector(TvarVD,1,NCOVMAX);
                   13052:   free_ivector(TvarVDind,1,NCOVMAX);
                   13053:   free_ivector(TvarVQ,1,NCOVMAX);
                   13054:   free_ivector(TvarVQind,1,NCOVMAX);
1.230     brouard  13055:   free_ivector(Tvarsel,1,NCOVMAX);
                   13056:   free_vector(Tvalsel,1,NCOVMAX);
1.227     brouard  13057:   free_ivector(Tposprod,1,NCOVMAX);
                   13058:   free_ivector(Tprod,1,NCOVMAX);
                   13059:   free_ivector(Tvaraff,1,NCOVMAX);
                   13060:   free_ivector(invalidvarcomb,1,ncovcombmax);
                   13061:   free_ivector(Tage,1,NCOVMAX);
                   13062:   free_ivector(Tmodelind,1,NCOVMAX);
1.228     brouard  13063:   free_ivector(TmodelInvind,1,NCOVMAX);
                   13064:   free_ivector(TmodelInvQind,1,NCOVMAX);
1.227     brouard  13065:   
                   13066:   free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
                   13067:   /* free_imatrix(codtab,1,100,1,10); */
1.126     brouard  13068:   fflush(fichtm);
                   13069:   fflush(ficgp);
                   13070:   
1.227     brouard  13071:   
1.126     brouard  13072:   if((nberr >0) || (nbwarn>0)){
1.216     brouard  13073:     printf("End of Imach with %d errors and/or %d warnings. Please look at the log file for details.\n",nberr,nbwarn);
                   13074:     fprintf(ficlog,"End of Imach with %d errors and/or warnings %d. Please look at the log file for details.\n",nberr,nbwarn);
1.126     brouard  13075:   }else{
                   13076:     printf("End of Imach\n");
                   13077:     fprintf(ficlog,"End of Imach\n");
                   13078:   }
                   13079:   printf("See log file on %s\n",filelog);
                   13080:   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
1.157     brouard  13081:   /*(void) gettimeofday(&end_time,&tzp);*/
                   13082:   rend_time = time(NULL);  
                   13083:   end_time = *localtime(&rend_time);
                   13084:   /* tml = *localtime(&end_time.tm_sec); */
                   13085:   strcpy(strtend,asctime(&end_time));
1.126     brouard  13086:   printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
                   13087:   fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
1.157     brouard  13088:   printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
1.227     brouard  13089:   
1.157     brouard  13090:   printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
                   13091:   fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
                   13092:   fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
1.126     brouard  13093:   /*  printf("Total time was %d uSec.\n", total_usecs);*/
                   13094: /*   if(fileappend(fichtm,optionfilehtm)){ */
                   13095:   fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13096:   fclose(fichtm);
                   13097:   fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
                   13098:   fclose(fichtmcov);
                   13099:   fclose(ficgp);
                   13100:   fclose(ficlog);
                   13101:   /*------ End -----------*/
1.227     brouard  13102:   
1.281     brouard  13103: 
                   13104: /* Executes gnuplot */
1.227     brouard  13105:   
                   13106:   printf("Before Current directory %s!\n",pathcd);
1.184     brouard  13107: #ifdef WIN32
1.227     brouard  13108:   if (_chdir(pathcd) != 0)
                   13109:     printf("Can't move to directory %s!\n",path);
                   13110:   if(_getcwd(pathcd,MAXLINE) > 0)
1.184     brouard  13111: #else
1.227     brouard  13112:     if(chdir(pathcd) != 0)
                   13113:       printf("Can't move to directory %s!\n", path);
                   13114:   if (getcwd(pathcd, MAXLINE) > 0)
1.184     brouard  13115: #endif 
1.126     brouard  13116:     printf("Current directory %s!\n",pathcd);
                   13117:   /*strcat(plotcmd,CHARSEPARATOR);*/
                   13118:   sprintf(plotcmd,"gnuplot");
1.157     brouard  13119: #ifdef _WIN32
1.126     brouard  13120:   sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
                   13121: #endif
                   13122:   if(!stat(plotcmd,&info)){
1.158     brouard  13123:     printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13124:     if(!stat(getenv("GNUPLOTBIN"),&info)){
1.158     brouard  13125:       printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
1.126     brouard  13126:     }else
                   13127:       strcpy(pplotcmd,plotcmd);
1.157     brouard  13128: #ifdef __unix
1.126     brouard  13129:     strcpy(plotcmd,GNUPLOTPROGRAM);
                   13130:     if(!stat(plotcmd,&info)){
1.158     brouard  13131:       printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
1.126     brouard  13132:     }else
                   13133:       strcpy(pplotcmd,plotcmd);
                   13134: #endif
                   13135:   }else
                   13136:     strcpy(pplotcmd,plotcmd);
                   13137:   
                   13138:   sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
1.158     brouard  13139:   printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
1.292     brouard  13140:   strcpy(pplotcmd,plotcmd);
1.227     brouard  13141:   
1.126     brouard  13142:   if((outcmd=system(plotcmd)) != 0){
1.292     brouard  13143:     printf("Error in gnuplot, command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
1.154     brouard  13144:     printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
1.152     brouard  13145:     sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
1.292     brouard  13146:     if((outcmd=system(plotcmd)) != 0){
1.153     brouard  13147:       printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
1.292     brouard  13148:       strcpy(plotcmd,pplotcmd);
                   13149:     }
1.126     brouard  13150:   }
1.158     brouard  13151:   printf(" Successful, please wait...");
1.126     brouard  13152:   while (z[0] != 'q') {
                   13153:     /* chdir(path); */
1.154     brouard  13154:     printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
1.126     brouard  13155:     scanf("%s",z);
                   13156: /*     if (z[0] == 'c') system("./imach"); */
                   13157:     if (z[0] == 'e') {
1.158     brouard  13158: #ifdef __APPLE__
1.152     brouard  13159:       sprintf(pplotcmd, "open %s", optionfilehtm);
1.157     brouard  13160: #elif __linux
                   13161:       sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
1.153     brouard  13162: #else
1.152     brouard  13163:       sprintf(pplotcmd, "%s", optionfilehtm);
1.153     brouard  13164: #endif
                   13165:       printf("Starting browser with: %s",pplotcmd);fflush(stdout);
                   13166:       system(pplotcmd);
1.126     brouard  13167:     }
                   13168:     else if (z[0] == 'g') system(plotcmd);
                   13169:     else if (z[0] == 'q') exit(0);
                   13170:   }
1.227     brouard  13171: end:
1.126     brouard  13172:   while (z[0] != 'q') {
1.195     brouard  13173:     printf("\nType  q for exiting: "); fflush(stdout);
1.126     brouard  13174:     scanf("%s",z);
                   13175:   }
1.283     brouard  13176:   printf("End\n");
1.282     brouard  13177:   exit(0);
1.126     brouard  13178: }

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