Diff for /imach/src/imach.c between versions 1.50 and 1.210

version 1.50, 2002/06/26 23:25:02 version 1.210, 2015/11/18 17:41:20
Line 1 Line 1
 /* $Id$  /* $Id$
    Interpolated Markov Chain    $State$
     $Log$
   Short summary of the programme:    Revision 1.210  2015/11/18 17:41:20  brouard
      Summary: Start working on projected prevalences
   This program computes Healthy Life Expectancies from  
   cross-longitudinal data. Cross-longitudinal data consist in: -1- a    Revision 1.209  2015/11/17 22:12:03  brouard
   first survey ("cross") where individuals from different ages are    Summary: Adding ftolpl parameter
   interviewed on their health status or degree of disability (in the    Author: N Brouard
   case of a health survey which is our main interest) -2- at least a  
   second wave of interviews ("longitudinal") which measure each change    We had difficulties to get smoothed confidence intervals. It was due
   (if any) in individual health status.  Health expectancies are    to the period prevalence which wasn't computed accurately. The inner
   computed from the time spent in each health state according to a    parameter ftolpl is now an outer parameter of the .imach parameter
   model. More health states you consider, more time is necessary to reach the    file after estepm. If ftolpl is small 1.e-4 and estepm too,
   Maximum Likelihood of the parameters involved in the model.  The    computation are long.
   simplest model is the multinomial logistic model where pij is the  
   probability to be observed in state j at the second wave    Revision 1.208  2015/11/17 14:31:57  brouard
   conditional to be observed in state i at the first wave. Therefore    Summary: temporary
   the model is: log(pij/pii)= aij + bij*age+ cij*sex + etc , where  
   'age' is age and 'sex' is a covariate. If you want to have a more    Revision 1.207  2015/10/27 17:36:57  brouard
   complex model than "constant and age", you should modify the program    *** empty log message ***
   where the markup *Covariates have to be included here again* invites  
   you to do it.  More covariates you add, slower the    Revision 1.206  2015/10/24 07:14:11  brouard
   convergence.    *** empty log message ***
   
   The advantage of this computer programme, compared to a simple    Revision 1.205  2015/10/23 15:50:53  brouard
   multinomial logistic model, is clear when the delay between waves is not    Summary: 0.98r3 some clarification for graphs on likelihood contributions
   identical for each individual. Also, if a individual missed an  
   intermediate interview, the information is lost, but taken into    Revision 1.204  2015/10/01 16:20:26  brouard
   account using an interpolation or extrapolation.      Summary: Some new graphs of contribution to likelihood
   
   hPijx is the probability to be observed in state i at age x+h    Revision 1.203  2015/09/30 17:45:14  brouard
   conditional to the observed state i at age x. The delay 'h' can be    Summary: looking at better estimation of the hessian
   split into an exact number (nh*stepm) of unobserved intermediate  
   states. This elementary transition (by month or quarter trimester,    Also a better criteria for convergence to the period prevalence And
   semester or year) is model as a multinomial logistic.  The hPx    therefore adding the number of years needed to converge. (The
   matrix is simply the matrix product of nh*stepm elementary matrices    prevalence in any alive state shold sum to one
   and the contribution of each individual to the likelihood is simply  
   hPijx.    Revision 1.202  2015/09/22 19:45:16  brouard
     Summary: Adding some overall graph on contribution to likelihood. Might change
   Also this programme outputs the covariance matrix of the parameters but also  
   of the life expectancies. It also computes the prevalence limits.    Revision 1.201  2015/09/15 17:34:58  brouard
      Summary: 0.98r0
   Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).  
            Institut national d'études démographiques, Paris.    - Some new graphs like suvival functions
   This software have been partly granted by Euro-REVES, a concerted action    - Some bugs fixed like model=1+age+V2.
   from the European Union.  
   It is copyrighted identically to a GNU software product, ie programme and    Revision 1.200  2015/09/09 16:53:55  brouard
   software can be distributed freely for non commercial use. Latest version    Summary: Big bug thanks to Flavia
   can be accessed at http://euroreves.ined.fr/imach .  
   **********************************************************************/    Even model=1+age+V2. did not work anymore
    
 #include <math.h>    Revision 1.199  2015/09/07 14:09:23  brouard
 #include <stdio.h>    Summary: 0.98q6 changing default small png format for graph to vectorized svg.
 #include <stdlib.h>  
 #include <unistd.h>    Revision 1.198  2015/09/03 07:14:39  brouard
     Summary: 0.98q5 Flavia
 #define MAXLINE 256  
 #define GNUPLOTPROGRAM "gnuplot"    Revision 1.197  2015/09/01 18:24:39  brouard
 /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/    *** empty log message ***
 #define FILENAMELENGTH 80  
 /*#define DEBUG*/    Revision 1.196  2015/08/18 23:17:52  brouard
 #define windows    Summary: 0.98q5
 #define GLOCK_ERROR_NOPATH              -1      /* empty path */  
 #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */    Revision 1.195  2015/08/18 16:28:39  brouard
     Summary: Adding a hack for testing purpose
 #define MAXPARM 30 /* Maximum number of parameters for the optimization */  
 #define NPARMAX 64 /* (nlstate+ndeath-1)*nlstate*ncovmodel */    After reading the title, ftol and model lines, if the comment line has
     a q, starting with #q, the answer at the end of the run is quit. It
 #define NINTERVMAX 8    permits to run test files in batch with ctest. The former workaround was
 #define NLSTATEMAX 8 /* Maximum number of live states (for func) */    $ echo q | imach foo.imach
 #define NDEATHMAX 8 /* Maximum number of dead states (for func) */  
 #define NCOVMAX 8 /* Maximum number of covariates */    Revision 1.194  2015/08/18 13:32:00  brouard
 #define MAXN 20000    Summary:  Adding error when the covariance matrix doesn't contain the exact number of lines required by the model line.
 #define YEARM 12. /* Number of months per year */  
 #define AGESUP 130    Revision 1.193  2015/08/04 07:17:42  brouard
 #define AGEBASE 40    Summary: 0.98q4
 #ifdef windows  
 #define DIRSEPARATOR '\\'    Revision 1.192  2015/07/16 16:49:02  brouard
 #define ODIRSEPARATOR '/'    Summary: Fixing some outputs
 #else  
 #define DIRSEPARATOR '/'    Revision 1.191  2015/07/14 10:00:33  brouard
 #define ODIRSEPARATOR '\\'    Summary: Some fixes
 #endif  
     Revision 1.190  2015/05/05 08:51:13  brouard
 char version[80]="Imach version 0.8i, June 2002, INED-EUROREVES ";    Summary: Adding digits in output parameters (7 digits instead of 6)
 int erreur; /* Error number */  
 int nvar;    Fix 1+age+.
 int cptcovn=0, cptcovage=0, cptcoveff=0,cptcov;  
 int npar=NPARMAX;    Revision 1.189  2015/04/30 14:45:16  brouard
 int nlstate=2; /* Number of live states */    Summary: 0.98q2
 int ndeath=1; /* Number of dead states */  
 int ncovmodel, ncovcol;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */    Revision 1.188  2015/04/30 08:27:53  brouard
 int popbased=0;    *** empty log message ***
   
 int *wav; /* Number of waves for this individuual 0 is possible */    Revision 1.187  2015/04/29 09:11:15  brouard
 int maxwav; /* Maxim number of waves */    *** empty log message ***
 int jmin, jmax; /* min, max spacing between 2 waves */  
 int mle, weightopt;    Revision 1.186  2015/04/23 12:01:52  brouard
 int **mw; /* mw[mi][i] is number of the mi wave for this individual */    Summary: V1*age is working now, version 0.98q1
 int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */  
 double jmean; /* Mean space between 2 waves */    Some codes had been disabled in order to simplify and Vn*age was
 double **oldm, **newm, **savm; /* Working pointers to matrices */    working in the optimization phase, ie, giving correct MLE parameters,
 double **oldms, **newms, **savms; /* Fixed working pointers to matrices */    but, as usual, outputs were not correct and program core dumped.
 FILE *fic,*ficpar, *ficparo,*ficres,  *ficrespl, *ficrespij, *ficrest,*ficresf,*ficrespop;  
 FILE *ficlog;    Revision 1.185  2015/03/11 13:26:42  brouard
 FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;    Summary: Inclusion of compile and links command line for Intel Compiler
 FILE *ficresprobmorprev;  
 FILE *fichtm; /* Html File */    Revision 1.184  2015/03/11 11:52:39  brouard
 FILE *ficreseij;    Summary: Back from Windows 8. Intel Compiler
 char filerese[FILENAMELENGTH];  
 FILE  *ficresvij;    Revision 1.183  2015/03/10 20:34:32  brouard
 char fileresv[FILENAMELENGTH];    Summary: 0.98q0, trying with directest, mnbrak fixed
 FILE  *ficresvpl;  
 char fileresvpl[FILENAMELENGTH];    We use directest instead of original Powell test; probably no
 char title[MAXLINE];    incidence on the results, but better justifications;
 char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];    We fixed Numerical Recipes mnbrak routine which was wrong and gave
 char optionfilext[10], optionfilefiname[FILENAMELENGTH], plotcmd[FILENAMELENGTH];    wrong results.
   
 char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];    Revision 1.182  2015/02/12 08:19:57  brouard
 char filelog[FILENAMELENGTH]; /* Log file */    Summary: Trying to keep directest which seems simpler and more general
 char filerest[FILENAMELENGTH];    Author: Nicolas Brouard
 char fileregp[FILENAMELENGTH];  
 char popfile[FILENAMELENGTH];    Revision 1.181  2015/02/11 23:22:24  brouard
     Summary: Comments on Powell added
 char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH];  
     Author:
 #define NR_END 1  
 #define FREE_ARG char*    Revision 1.180  2015/02/11 17:33:45  brouard
 #define FTOL 1.0e-10    Summary: Finishing move from main to function (hpijx and prevalence_limit)
   
 #define NRANSI    Revision 1.179  2015/01/04 09:57:06  brouard
 #define ITMAX 200    Summary: back to OS/X
   
 #define TOL 2.0e-4    Revision 1.178  2015/01/04 09:35:48  brouard
     *** empty log message ***
 #define CGOLD 0.3819660  
 #define ZEPS 1.0e-10    Revision 1.177  2015/01/03 18:40:56  brouard
 #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d);    Summary: Still testing ilc32 on OSX
   
 #define GOLD 1.618034    Revision 1.176  2015/01/03 16:45:04  brouard
 #define GLIMIT 100.0    *** empty log message ***
 #define TINY 1.0e-20  
     Revision 1.175  2015/01/03 16:33:42  brouard
 static double maxarg1,maxarg2;    *** empty log message ***
 #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))  
 #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))    Revision 1.174  2015/01/03 16:15:49  brouard
      Summary: Still in cross-compilation
 #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))  
 #define rint(a) floor(a+0.5)    Revision 1.173  2015/01/03 12:06:26  brouard
     Summary: trying to detect cross-compilation
 static double sqrarg;  
 #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)    Revision 1.172  2014/12/27 12:07:47  brouard
 #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;}    Summary: Back from Visual Studio and Intel, options for compiling for Windows XP
   
 int imx;    Revision 1.171  2014/12/23 13:26:59  brouard
 int stepm;    Summary: Back from Visual C
 /* Stepm, step in month: minimum step interpolation*/  
     Still problem with utsname.h on Windows
 int estepm;  
 /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/    Revision 1.170  2014/12/23 11:17:12  brouard
     Summary: Cleaning some \%% back to %%
 int m,nb;  
 int *num, firstpass=0, lastpass=4,*cod, *ncodemax, *Tage;    The escape was mandatory for a specific compiler (which one?), but too many warnings.
 double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;  
 double **pmmij, ***probs, ***mobaverage;    Revision 1.169  2014/12/22 23:08:31  brouard
 double dateintmean=0;    Summary: 0.98p
   
 double *weight;    Outputs some informations on compiler used, OS etc. Testing on different platforms.
 int **s; /* Status */  
 double *agedc, **covar, idx;    Revision 1.168  2014/12/22 15:17:42  brouard
 int **nbcode, *Tcode, *Tvar, **codtab, **Tvard, *Tprod, cptcovprod, *Tvaraff;    Summary: update
   
 double ftol=FTOL; /* Tolerance for computing Max Likelihood */    Revision 1.167  2014/12/22 13:50:56  brouard
 double ftolhess; /* Tolerance for computing hessian */    Summary: Testing uname and compiler version and if compiled 32 or 64
   
 /**************** split *************************/    Testing on Linux 64
 static  int split( char *path, char *dirc, char *name, char *ext, char *finame )  
 {    Revision 1.166  2014/12/22 11:40:47  brouard
    char *s;                             /* pointer */    *** empty log message ***
    int  l1, l2;                         /* length counters */  
     Revision 1.165  2014/12/16 11:20:36  brouard
    l1 = strlen( path );                 /* length of path */    Summary: After compiling on Visual C
    if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );  
    s= strrchr( path, DIRSEPARATOR );            /* find last / */    * imach.c (Module): Merging 1.61 to 1.162
    if ( s == NULL ) {                   /* no directory, so use current */  
      /*if(strrchr(path, ODIRSEPARATOR )==NULL)    Revision 1.164  2014/12/16 10:52:11  brouard
        printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/    Summary: Merging with Visual C after suppressing some warnings for unused variables. Also fixing Saito's bug 0.98Xn
 #if     defined(__bsd__)                /* get current working directory */  
       extern char       *getwd( );    * imach.c (Module): Merging 1.61 to 1.162
   
       if ( getwd( dirc ) == NULL ) {    Revision 1.163  2014/12/16 10:30:11  brouard
 #else    * imach.c (Module): Merging 1.61 to 1.162
       extern char       *getcwd( );  
     Revision 1.162  2014/09/25 11:43:39  brouard
       if ( getcwd( dirc, FILENAME_MAX ) == NULL ) {    Summary: temporary backup 0.99!
 #endif  
          return( GLOCK_ERROR_GETCWD );    Revision 1.1  2014/09/16 11:06:58  brouard
       }    Summary: With some code (wrong) for nlopt
       strcpy( name, path );             /* we've got it */  
    } else {                             /* strip direcotry from path */    Author:
       s++;                              /* after this, the filename */  
       l2 = strlen( s );                 /* length of filename */    Revision 1.161  2014/09/15 20:41:41  brouard
       if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );    Summary: Problem with macro SQR on Intel compiler
       strcpy( name, s );                /* save file name */  
       strncpy( dirc, path, l1 - l2 );   /* now the directory */    Revision 1.160  2014/09/02 09:24:05  brouard
       dirc[l1-l2] = 0;                  /* add zero */    *** empty log message ***
    }  
    l1 = strlen( dirc );                 /* length of directory */    Revision 1.159  2014/09/01 10:34:10  brouard
 #ifdef windows    Summary: WIN32
    if ( dirc[l1-1] != '\\' ) { dirc[l1] = '\\'; dirc[l1+1] = 0; }    Author: Brouard
 #else  
    if ( dirc[l1-1] != '/' ) { dirc[l1] = '/'; dirc[l1+1] = 0; }    Revision 1.158  2014/08/27 17:11:51  brouard
 #endif    *** empty log message ***
    s = strrchr( name, '.' );            /* find last / */  
    s++;    Revision 1.157  2014/08/27 16:26:55  brouard
    strcpy(ext,s);                       /* save extension */    Summary: Preparing windows Visual studio version
    l1= strlen( name);    Author: Brouard
    l2= strlen( s)+1;  
    strncpy( finame, name, l1-l2);    In order to compile on Visual studio, time.h is now correct and time_t
    finame[l1-l2]= 0;    and tm struct should be used. difftime should be used but sometimes I
    return( 0 );                         /* we're done */    just make the differences in raw time format (time(&now).
 }    Trying to suppress #ifdef LINUX
     Add xdg-open for __linux in order to open default browser.
   
 /******************************************/    Revision 1.156  2014/08/25 20:10:10  brouard
     *** empty log message ***
 void replace(char *s, char*t)  
 {    Revision 1.155  2014/08/25 18:32:34  brouard
   int i;    Summary: New compile, minor changes
   int lg=20;    Author: Brouard
   i=0;  
   lg=strlen(t);    Revision 1.154  2014/06/20 17:32:08  brouard
   for(i=0; i<= lg; i++) {    Summary: Outputs now all graphs of convergence to period prevalence
     (s[i] = t[i]);  
     if (t[i]== '\\') s[i]='/';    Revision 1.153  2014/06/20 16:45:46  brouard
   }    Summary: If 3 live state, convergence to period prevalence on same graph
 }    Author: Brouard
   
 int nbocc(char *s, char occ)    Revision 1.152  2014/06/18 17:54:09  brouard
 {    Summary: open browser, use gnuplot on same dir than imach if not found in the path
   int i,j=0;  
   int lg=20;    Revision 1.151  2014/06/18 16:43:30  brouard
   i=0;    *** empty log message ***
   lg=strlen(s);  
   for(i=0; i<= lg; i++) {    Revision 1.150  2014/06/18 16:42:35  brouard
   if  (s[i] == occ ) j++;    Summary: If gnuplot is not in the path try on same directory than imach binary (OSX)
   }    Author: brouard
   return j;  
 }    Revision 1.149  2014/06/18 15:51:14  brouard
     Summary: Some fixes in parameter files errors
 void cutv(char *u,char *v, char*t, char occ)    Author: Nicolas Brouard
 {  
   /* cuts string t into u and v where u is ended by char occ excluding it    Revision 1.148  2014/06/17 17:38:48  brouard
      and v is after occ excluding it too : ex cutv(u,v,"abcdef2ghi2j",2)    Summary: Nothing new
      gives u="abcedf" and v="ghi2j" */    Author: Brouard
   int i,lg,j,p=0;  
   i=0;    Just a new packaging for OS/X version 0.98nS
   for(j=0; j<=strlen(t)-1; j++) {  
     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1;    Revision 1.147  2014/06/16 10:33:11  brouard
   }    *** empty log message ***
   
   lg=strlen(t);    Revision 1.146  2014/06/16 10:20:28  brouard
   for(j=0; j<p; j++) {    Summary: Merge
     (u[j] = t[j]);    Author: Brouard
   }  
      u[p]='\0';    Merge, before building revised version.
   
    for(j=0; j<= lg; j++) {    Revision 1.145  2014/06/10 21:23:15  brouard
     if (j>=(p+1))(v[j-p-1] = t[j]);    Summary: Debugging with valgrind
   }    Author: Nicolas Brouard
 }  
     Lot of changes in order to output the results with some covariates
 /********************** nrerror ********************/    After the Edimburgh REVES conference 2014, it seems mandatory to
     improve the code.
 void nrerror(char error_text[])    No more memory valgrind error but a lot has to be done in order to
 {    continue the work of splitting the code into subroutines.
   fprintf(stderr,"ERREUR ...\n");    Also, decodemodel has been improved. Tricode is still not
   fprintf(stderr,"%s\n",error_text);    optimal. nbcode should be improved. Documentation has been added in
   exit(1);    the source code.
 }  
 /*********************** vector *******************/    Revision 1.143  2014/01/26 09:45:38  brouard
 double *vector(int nl, int nh)    Summary: Version 0.98nR (to be improved, but gives same optimization results as 0.98k. Nice, promising
 {  
   double *v;    * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
   v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));    (Module): Version 0.98nR Running ok, but output format still only works for three covariates.
   if (!v) nrerror("allocation failure in vector");  
   return v-nl+NR_END;    Revision 1.142  2014/01/26 03:57:36  brouard
 }    Summary: gnuplot changed plot w l 1 has to be changed to plot w l lt 2
   
 /************************ free vector ******************/    * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
 void free_vector(double*v, int nl, int nh)  
 {    Revision 1.141  2014/01/26 02:42:01  brouard
   free((FREE_ARG)(v+nl-NR_END));    * imach.c (Module): Trying to merge old staffs together while being at Tokyo. Not tested...
 }  
     Revision 1.140  2011/09/02 10:37:54  brouard
 /************************ivector *******************************/    Summary: times.h is ok with mingw32 now.
 int *ivector(long nl,long nh)  
 {    Revision 1.139  2010/06/14 07:50:17  brouard
   int *v;    After the theft of my laptop, I probably lost some lines of codes which were not uploaded to the CVS tree.
   v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));    I remember having already fixed agemin agemax which are pointers now but not cvs saved.
   if (!v) nrerror("allocation failure in ivector");  
   return v-nl+NR_END;    Revision 1.138  2010/04/30 18:19:40  brouard
 }    *** empty log message ***
   
 /******************free ivector **************************/    Revision 1.137  2010/04/29 18:11:38  brouard
 void free_ivector(int *v, long nl, long nh)    (Module): Checking covariates for more complex models
 {    than V1+V2. A lot of change to be done. Unstable.
   free((FREE_ARG)(v+nl-NR_END));  
 }    Revision 1.136  2010/04/26 20:30:53  brouard
     (Module): merging some libgsl code. Fixing computation
 /******************* imatrix *******************************/    of likelione (using inter/intrapolation if mle = 0) in order to
 int **imatrix(long nrl, long nrh, long ncl, long nch)    get same likelihood as if mle=1.
      /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */    Some cleaning of code and comments added.
 {  
   long i, nrow=nrh-nrl+1,ncol=nch-ncl+1;    Revision 1.135  2009/10/29 15:33:14  brouard
   int **m;    (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
    
   /* allocate pointers to rows */    Revision 1.134  2009/10/29 13:18:53  brouard
   m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*)));    (Module): Now imach stops if date of birth, at least year of birth, is not given. Some cleaning of the code.
   if (!m) nrerror("allocation failure 1 in matrix()");  
   m += NR_END;    Revision 1.133  2009/07/06 10:21:25  brouard
   m -= nrl;    just nforces
    
      Revision 1.132  2009/07/06 08:22:05  brouard
   /* allocate rows and set pointers to them */    Many tings
   m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int)));  
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");    Revision 1.131  2009/06/20 16:22:47  brouard
   m[nrl] += NR_END;    Some dimensions resccaled
   m[nrl] -= ncl;  
      Revision 1.130  2009/05/26 06:44:34  brouard
   for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol;    (Module): Max Covariate is now set to 20 instead of 8. A
      lot of cleaning with variables initialized to 0. Trying to make
   /* return pointer to array of pointers to rows */    V2+V3*age+V1+V4 strb=V3*age+V1+V4 working better.
   return m;  
 }    Revision 1.129  2007/08/31 13:49:27  lievre
     Modification of the way of exiting when the covariate is not binary in order to see on the window the error message before exiting
 /****************** free_imatrix *************************/  
 void free_imatrix(m,nrl,nrh,ncl,nch)    Revision 1.128  2006/06/30 13:02:05  brouard
       int **m;    (Module): Clarifications on computing e.j
       long nch,ncl,nrh,nrl;  
      /* free an int matrix allocated by imatrix() */    Revision 1.127  2006/04/28 18:11:50  brouard
 {    (Module): Yes the sum of survivors was wrong since
   free((FREE_ARG) (m[nrl]+ncl-NR_END));    imach-114 because nhstepm was no more computed in the age
   free((FREE_ARG) (m+nrl-NR_END));    loop. Now we define nhstepma in the age loop.
 }    (Module): In order to speed up (in case of numerous covariates) we
     compute health expectancies (without variances) in a first step
 /******************* matrix *******************************/    and then all the health expectancies with variances or standard
 double **matrix(long nrl, long nrh, long ncl, long nch)    deviation (needs data from the Hessian matrices) which slows the
 {    computation.
   long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;    In the future we should be able to stop the program is only health
   double **m;    expectancies and graph are needed without standard deviations.
   
   m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));    Revision 1.126  2006/04/28 17:23:28  brouard
   if (!m) nrerror("allocation failure 1 in matrix()");    (Module): Yes the sum of survivors was wrong since
   m += NR_END;    imach-114 because nhstepm was no more computed in the age
   m -= nrl;    loop. Now we define nhstepma in the age loop.
     Version 0.98h
   m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));  
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");    Revision 1.125  2006/04/04 15:20:31  lievre
   m[nrl] += NR_END;    Errors in calculation of health expectancies. Age was not initialized.
   m[nrl] -= ncl;    Forecasting file added.
   
   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;    Revision 1.124  2006/03/22 17:13:53  lievre
   return m;    Parameters are printed with %lf instead of %f (more numbers after the comma).
 }    The log-likelihood is printed in the log file
   
 /*************************free matrix ************************/    Revision 1.123  2006/03/20 10:52:43  brouard
 void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)    * imach.c (Module): <title> changed, corresponds to .htm file
 {    name. <head> headers where missing.
   free((FREE_ARG)(m[nrl]+ncl-NR_END));  
   free((FREE_ARG)(m+nrl-NR_END));    * imach.c (Module): Weights can have a decimal point as for
 }    English (a comma might work with a correct LC_NUMERIC environment,
     otherwise the weight is truncated).
 /******************* ma3x *******************************/    Modification of warning when the covariates values are not 0 or
 double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)    1.
 {    Version 0.98g
   long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;  
   double ***m;    Revision 1.122  2006/03/20 09:45:41  brouard
     (Module): Weights can have a decimal point as for
   m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));    English (a comma might work with a correct LC_NUMERIC environment,
   if (!m) nrerror("allocation failure 1 in matrix()");    otherwise the weight is truncated).
   m += NR_END;    Modification of warning when the covariates values are not 0 or
   m -= nrl;    1.
     Version 0.98g
   m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));  
   if (!m[nrl]) nrerror("allocation failure 2 in matrix()");    Revision 1.121  2006/03/16 17:45:01  lievre
   m[nrl] += NR_END;    * imach.c (Module): Comments concerning covariates added
   m[nrl] -= ncl;  
     * imach.c (Module): refinements in the computation of lli if
   for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;    status=-2 in order to have more reliable computation if stepm is
     not 1 month. Version 0.98f
   m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));  
   if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");    Revision 1.120  2006/03/16 15:10:38  lievre
   m[nrl][ncl] += NR_END;    (Module): refinements in the computation of lli if
   m[nrl][ncl] -= nll;    status=-2 in order to have more reliable computation if stepm is
   for (j=ncl+1; j<=nch; j++)    not 1 month. Version 0.98f
     m[nrl][j]=m[nrl][j-1]+nlay;  
      Revision 1.119  2006/03/15 17:42:26  brouard
   for (i=nrl+1; i<=nrh; i++) {    (Module): Bug if status = -2, the loglikelihood was
     m[i][ncl]=m[i-1l][ncl]+ncol*nlay;    computed as likelihood omitting the logarithm. Version O.98e
     for (j=ncl+1; j<=nch; j++)  
       m[i][j]=m[i][j-1]+nlay;    Revision 1.118  2006/03/14 18:20:07  brouard
   }    (Module): varevsij Comments added explaining the second
   return m;    table of variances if popbased=1 .
 }    (Module): Covariances of eij, ekl added, graphs fixed, new html link.
     (Module): Function pstamp added
 /*************************free ma3x ************************/    (Module): Version 0.98d
 void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)  
 {    Revision 1.117  2006/03/14 17:16:22  brouard
   free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));    (Module): varevsij Comments added explaining the second
   free((FREE_ARG)(m[nrl]+ncl-NR_END));    table of variances if popbased=1 .
   free((FREE_ARG)(m+nrl-NR_END));    (Module): Covariances of eij, ekl added, graphs fixed, new html link.
 }    (Module): Function pstamp added
     (Module): Version 0.98d
 /***************** f1dim *************************/  
 extern int ncom;    Revision 1.116  2006/03/06 10:29:27  brouard
 extern double *pcom,*xicom;    (Module): Variance-covariance wrong links and
 extern double (*nrfunc)(double []);    varian-covariance of ej. is needed (Saito).
    
 double f1dim(double x)    Revision 1.115  2006/02/27 12:17:45  brouard
 {    (Module): One freematrix added in mlikeli! 0.98c
   int j;  
   double f;    Revision 1.114  2006/02/26 12:57:58  brouard
   double *xt;    (Module): Some improvements in processing parameter
      filename with strsep.
   xt=vector(1,ncom);  
   for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j];    Revision 1.113  2006/02/24 14:20:24  brouard
   f=(*nrfunc)(xt);    (Module): Memory leaks checks with valgrind and:
   free_vector(xt,1,ncom);    datafile was not closed, some imatrix were not freed and on matrix
   return f;    allocation too.
 }  
     Revision 1.112  2006/01/30 09:55:26  brouard
 /*****************brent *************************/    (Module): Back to gnuplot.exe instead of wgnuplot.exe
 double brent(double ax, double bx, double cx, double (*f)(double), double tol,  double *xmin)  
 {    Revision 1.111  2006/01/25 20:38:18  brouard
   int iter;    (Module): Lots of cleaning and bugs added (Gompertz)
   double a,b,d,etemp;    (Module): Comments can be added in data file. Missing date values
   double fu,fv,fw,fx;    can be a simple dot '.'.
   double ftemp;  
   double p,q,r,tol1,tol2,u,v,w,x,xm;    Revision 1.110  2006/01/25 00:51:50  brouard
   double e=0.0;    (Module): Lots of cleaning and bugs added (Gompertz)
    
   a=(ax < cx ? ax : cx);    Revision 1.109  2006/01/24 19:37:15  brouard
   b=(ax > cx ? ax : cx);    (Module): Comments (lines starting with a #) are allowed in data.
   x=w=v=bx;  
   fw=fv=fx=(*f)(x);    Revision 1.108  2006/01/19 18:05:42  lievre
   for (iter=1;iter<=ITMAX;iter++) {    Gnuplot problem appeared...
     xm=0.5*(a+b);    To be fixed
     tol2=2.0*(tol1=tol*fabs(x)+ZEPS);  
     /*          if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/    Revision 1.107  2006/01/19 16:20:37  brouard
     printf(".");fflush(stdout);    Test existence of gnuplot in imach path
     fprintf(ficlog,".");fflush(ficlog);  
 #ifdef DEBUG    Revision 1.106  2006/01/19 13:24:36  brouard
     printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);    Some cleaning and links added in html output
     fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);  
     /*          if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */    Revision 1.105  2006/01/05 20:23:19  lievre
 #endif    *** empty log message ***
     if (fabs(x-xm) <= (tol2-0.5*(b-a))){  
       *xmin=x;    Revision 1.104  2005/09/30 16:11:43  lievre
       return fx;    (Module): sump fixed, loop imx fixed, and simplifications.
     }    (Module): If the status is missing at the last wave but we know
     ftemp=fu;    that the person is alive, then we can code his/her status as -2
     if (fabs(e) > tol1) {    (instead of missing=-1 in earlier versions) and his/her
       r=(x-w)*(fx-fv);    contributions to the likelihood is 1 - Prob of dying from last
       q=(x-v)*(fx-fw);    health status (= 1-p13= p11+p12 in the easiest case of somebody in
       p=(x-v)*q-(x-w)*r;    the healthy state at last known wave). Version is 0.98
       q=2.0*(q-r);  
       if (q > 0.0) p = -p;    Revision 1.103  2005/09/30 15:54:49  lievre
       q=fabs(q);    (Module): sump fixed, loop imx fixed, and simplifications.
       etemp=e;  
       e=d;    Revision 1.102  2004/09/15 17:31:30  brouard
       if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x))    Add the possibility to read data file including tab characters.
         d=CGOLD*(e=(x >= xm ? a-x : b-x));  
       else {    Revision 1.101  2004/09/15 10:38:38  brouard
         d=p/q;    Fix on curr_time
         u=x+d;  
         if (u-a < tol2 || b-u < tol2)    Revision 1.100  2004/07/12 18:29:06  brouard
           d=SIGN(tol1,xm-x);    Add version for Mac OS X. Just define UNIX in Makefile
       }  
     } else {    Revision 1.99  2004/06/05 08:57:40  brouard
       d=CGOLD*(e=(x >= xm ? a-x : b-x));    *** empty log message ***
     }  
     u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d));    Revision 1.98  2004/05/16 15:05:56  brouard
     fu=(*f)(u);    New version 0.97 . First attempt to estimate force of mortality
     if (fu <= fx) {    directly from the data i.e. without the need of knowing the health
       if (u >= x) a=x; else b=x;    state at each age, but using a Gompertz model: log u =a + b*age .
       SHFT(v,w,x,u)    This is the basic analysis of mortality and should be done before any
         SHFT(fv,fw,fx,fu)    other analysis, in order to test if the mortality estimated from the
         } else {    cross-longitudinal survey is different from the mortality estimated
           if (u < x) a=u; else b=u;    from other sources like vital statistic data.
           if (fu <= fw || w == x) {  
             v=w;    The same imach parameter file can be used but the option for mle should be -3.
             w=u;  
             fv=fw;    Agnès, who wrote this part of the code, tried to keep most of the
             fw=fu;    former routines in order to include the new code within the former code.
           } else if (fu <= fv || v == x || v == w) {  
             v=u;    The output is very simple: only an estimate of the intercept and of
             fv=fu;    the slope with 95% confident intervals.
           }  
         }    Current limitations:
   }    A) Even if you enter covariates, i.e. with the
   nrerror("Too many iterations in brent");    model= V1+V2 equation for example, the programm does only estimate a unique global model without covariates.
   *xmin=x;    B) There is no computation of Life Expectancy nor Life Table.
   return fx;  
 }    Revision 1.97  2004/02/20 13:25:42  lievre
     Version 0.96d. Population forecasting command line is (temporarily)
 /****************** mnbrak ***********************/    suppressed.
   
 void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc,    Revision 1.96  2003/07/15 15:38:55  brouard
             double (*func)(double))    * imach.c (Repository): Errors in subdirf, 2, 3 while printing tmpout is
 {    rewritten within the same printf. Workaround: many printfs.
   double ulim,u,r,q, dum;  
   double fu;    Revision 1.95  2003/07/08 07:54:34  brouard
      * imach.c (Repository):
   *fa=(*func)(*ax);    (Repository): Using imachwizard code to output a more meaningful covariance
   *fb=(*func)(*bx);    matrix (cov(a12,c31) instead of numbers.
   if (*fb > *fa) {  
     SHFT(dum,*ax,*bx,dum)    Revision 1.94  2003/06/27 13:00:02  brouard
       SHFT(dum,*fb,*fa,dum)    Just cleaning
       }  
   *cx=(*bx)+GOLD*(*bx-*ax);    Revision 1.93  2003/06/25 16:33:55  brouard
   *fc=(*func)(*cx);    (Module): On windows (cygwin) function asctime_r doesn't
   while (*fb > *fc) {    exist so I changed back to asctime which exists.
     r=(*bx-*ax)*(*fb-*fc);    (Module): Version 0.96b
     q=(*bx-*cx)*(*fb-*fa);  
     u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/    Revision 1.92  2003/06/25 16:30:45  brouard
       (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r));    (Module): On windows (cygwin) function asctime_r doesn't
     ulim=(*bx)+GLIMIT*(*cx-*bx);    exist so I changed back to asctime which exists.
     if ((*bx-u)*(u-*cx) > 0.0) {  
       fu=(*func)(u);    Revision 1.91  2003/06/25 15:30:29  brouard
     } else if ((*cx-u)*(u-ulim) > 0.0) {    * imach.c (Repository): Duplicated warning errors corrected.
       fu=(*func)(u);    (Repository): Elapsed time after each iteration is now output. It
       if (fu < *fc) {    helps to forecast when convergence will be reached. Elapsed time
         SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx))    is stamped in powell.  We created a new html file for the graphs
           SHFT(*fb,*fc,fu,(*func)(u))    concerning matrix of covariance. It has extension -cov.htm.
           }  
     } else if ((u-ulim)*(ulim-*cx) >= 0.0) {    Revision 1.90  2003/06/24 12:34:15  brouard
       u=ulim;    (Module): Some bugs corrected for windows. Also, when
       fu=(*func)(u);    mle=-1 a template is output in file "or"mypar.txt with the design
     } else {    of the covariance matrix to be input.
       u=(*cx)+GOLD*(*cx-*bx);  
       fu=(*func)(u);    Revision 1.89  2003/06/24 12:30:52  brouard
     }    (Module): Some bugs corrected for windows. Also, when
     SHFT(*ax,*bx,*cx,u)    mle=-1 a template is output in file "or"mypar.txt with the design
       SHFT(*fa,*fb,*fc,fu)    of the covariance matrix to be input.
       }  
 }    Revision 1.88  2003/06/23 17:54:56  brouard
     * imach.c (Repository): Create a sub-directory where all the secondary files are. Only imach, htm, gp and r(imach) are on the main directory. Correct time and other things.
 /*************** linmin ************************/  
     Revision 1.87  2003/06/18 12:26:01  brouard
 int ncom;    Version 0.96
 double *pcom,*xicom;  
 double (*nrfunc)(double []);    Revision 1.86  2003/06/17 20:04:08  brouard
      (Module): Change position of html and gnuplot routines and added
 void linmin(double p[], double xi[], int n, double *fret,double (*func)(double []))    routine fileappend.
 {  
   double brent(double ax, double bx, double cx,    Revision 1.85  2003/06/17 13:12:43  brouard
                double (*f)(double), double tol, double *xmin);    * imach.c (Repository): Check when date of death was earlier that
   double f1dim(double x);    current date of interview. It may happen when the death was just
   void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb,    prior to the death. In this case, dh was negative and likelihood
               double *fc, double (*func)(double));    was wrong (infinity). We still send an "Error" but patch by
   int j;    assuming that the date of death was just one stepm after the
   double xx,xmin,bx,ax;    interview.
   double fx,fb,fa;    (Repository): Because some people have very long ID (first column)
      we changed int to long in num[] and we added a new lvector for
   ncom=n;    memory allocation. But we also truncated to 8 characters (left
   pcom=vector(1,n);    truncation)
   xicom=vector(1,n);    (Repository): No more line truncation errors.
   nrfunc=func;  
   for (j=1;j<=n;j++) {    Revision 1.84  2003/06/13 21:44:43  brouard
     pcom[j]=p[j];    * imach.c (Repository): Replace "freqsummary" at a correct
     xicom[j]=xi[j];    place. It differs from routine "prevalence" which may be called
   }    many times. Probs is memory consuming and must be used with
   ax=0.0;    parcimony.
   xx=1.0;    Version 0.95a3 (should output exactly the same maximization than 0.8a2)
   mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  
   *fret=brent(ax,xx,bx,f1dim,TOL,&xmin);    Revision 1.83  2003/06/10 13:39:11  lievre
 #ifdef DEBUG    *** empty log message ***
   printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);  
   fprintf(ficlog,"retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);    Revision 1.82  2003/06/05 15:57:20  brouard
 #endif    Add log in  imach.c and  fullversion number is now printed.
   for (j=1;j<=n;j++) {  
     xi[j] *= xmin;  */
     p[j] += xi[j];  /*
   }     Interpolated Markov Chain
   free_vector(xicom,1,n);  
   free_vector(pcom,1,n);    Short summary of the programme:
 }    
     This program computes Healthy Life Expectancies from
 /*************** powell ************************/    cross-longitudinal data. Cross-longitudinal data consist in: -1- a
 void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret,    first survey ("cross") where individuals from different ages are
             double (*func)(double []))    interviewed on their health status or degree of disability (in the
 {    case of a health survey which is our main interest) -2- at least a
   void linmin(double p[], double xi[], int n, double *fret,    second wave of interviews ("longitudinal") which measure each change
               double (*func)(double []));    (if any) in individual health status.  Health expectancies are
   int i,ibig,j;    computed from the time spent in each health state according to a
   double del,t,*pt,*ptt,*xit;    model. More health states you consider, more time is necessary to reach the
   double fp,fptt;    Maximum Likelihood of the parameters involved in the model.  The
   double *xits;    simplest model is the multinomial logistic model where pij is the
   pt=vector(1,n);    probability to be observed in state j at the second wave
   ptt=vector(1,n);    conditional to be observed in state i at the first wave. Therefore
   xit=vector(1,n);    the model is: log(pij/pii)= aij + bij*age+ cij*sex + etc , where
   xits=vector(1,n);    'age' is age and 'sex' is a covariate. If you want to have a more
   *fret=(*func)(p);    complex model than "constant and age", you should modify the program
   for (j=1;j<=n;j++) pt[j]=p[j];    where the markup *Covariates have to be included here again* invites
   for (*iter=1;;++(*iter)) {    you to do it.  More covariates you add, slower the
     fp=(*fret);    convergence.
     ibig=0;  
     del=0.0;    The advantage of this computer programme, compared to a simple
     printf("\nPowell iter=%d -2*LL=%.12f",*iter,*fret);    multinomial logistic model, is clear when the delay between waves is not
     fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f",*iter,*fret);    identical for each individual. Also, if a individual missed an
     for (i=1;i<=n;i++)    intermediate interview, the information is lost, but taken into
       printf(" %d %.12f",i, p[i]);    account using an interpolation or extrapolation.  
     fprintf(ficlog," %d %.12f",i, p[i]);  
     printf("\n");    hPijx is the probability to be observed in state i at age x+h
     fprintf(ficlog,"\n");    conditional to the observed state i at age x. The delay 'h' can be
     for (i=1;i<=n;i++) {    split into an exact number (nh*stepm) of unobserved intermediate
       for (j=1;j<=n;j++) xit[j]=xi[j][i];    states. This elementary transition (by month, quarter,
       fptt=(*fret);    semester or year) is modelled as a multinomial logistic.  The hPx
 #ifdef DEBUG    matrix is simply the matrix product of nh*stepm elementary matrices
       printf("fret=%lf \n",*fret);    and the contribution of each individual to the likelihood is simply
       fprintf(ficlog,"fret=%lf \n",*fret);    hPijx.
 #endif  
       printf("%d",i);fflush(stdout);    Also this programme outputs the covariance matrix of the parameters but also
       fprintf(ficlog,"%d",i);fflush(ficlog);    of the life expectancies. It also computes the period (stable) prevalence. 
       linmin(p,xit,n,fret,func);    
       if (fabs(fptt-(*fret)) > del) {    Authors: Nicolas Brouard (brouard@ined.fr) and Agnès Lièvre (lievre@ined.fr).
         del=fabs(fptt-(*fret));             Institut national d'études démographiques, Paris.
         ibig=i;    This software have been partly granted by Euro-REVES, a concerted action
       }    from the European Union.
 #ifdef DEBUG    It is copyrighted identically to a GNU software product, ie programme and
       printf("%d %.12e",i,(*fret));    software can be distributed freely for non commercial use. Latest version
       fprintf(ficlog,"%d %.12e",i,(*fret));    can be accessed at http://euroreves.ined.fr/imach .
       for (j=1;j<=n;j++) {  
         xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);    Help to debug: LD_PRELOAD=/usr/local/lib/libnjamd.so ./imach foo.imach
         printf(" x(%d)=%.12e",j,xit[j]);    or better on gdb : set env LD_PRELOAD=/usr/local/lib/libnjamd.so
         fprintf(ficlog," x(%d)=%.12e",j,xit[j]);    
       }    **********************************************************************/
       for(j=1;j<=n;j++) {  /*
         printf(" p=%.12e",p[j]);    main
         fprintf(ficlog," p=%.12e",p[j]);    read parameterfile
       }    read datafile
       printf("\n");    concatwav
       fprintf(ficlog,"\n");    freqsummary
 #endif    if (mle >= 1)
     }      mlikeli
     if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) {    print results files
 #ifdef DEBUG    if mle==1 
       int k[2],l;       computes hessian
       k[0]=1;    read end of parameter file: agemin, agemax, bage, fage, estepm
       k[1]=-1;        begin-prev-date,...
       printf("Max: %.12e",(*func)(p));    open gnuplot file
       fprintf(ficlog,"Max: %.12e",(*func)(p));    open html file
       for (j=1;j<=n;j++) {    period (stable) prevalence      | pl_nom    1-1 2-2 etc by covariate
         printf(" %.12e",p[j]);     for age prevalim()             | #****** V1=0  V2=1  V3=1  V4=0 ******
         fprintf(ficlog," %.12e",p[j]);                                    | 65 1 0 2 1 3 1 4 0  0.96326 0.03674
       }      freexexit2 possible for memory heap.
       printf("\n");  
       fprintf(ficlog,"\n");    h Pij x                         | pij_nom  ficrestpij
       for(l=0;l<=1;l++) {     # Cov Agex agex+h hpijx with i,j= 1-1 1-2     1-3     2-1     2-2     2-3
         for (j=1;j<=n;j++) {         1  85   85    1.00000             0.00000 0.00000 0.00000 1.00000 0.00000
           ptt[j]=p[j]+(p[j]-pt[j])*k[l];         1  85   86    0.68299             0.22291 0.09410 0.71093 0.00000 0.28907
           printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);  
           fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);         1  65   99    0.00364             0.00322 0.99314 0.00350 0.00310 0.99340
         }         1  65  100    0.00214             0.00204 0.99581 0.00206 0.00196 0.99597
         printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));    variance of p one-step probabilities varprob  | prob_nom   ficresprob #One-step probabilities and stand. devi in ()
         fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));     Standard deviation of one-step probabilities | probcor_nom   ficresprobcor #One-step probabilities and correlation matrix
       }     Matrix of variance covariance of one-step probabilities |  probcov_nom ficresprobcov #One-step probabilities and covariance matrix
 #endif  
     forecasting if prevfcast==1 prevforecast call prevalence()
     health expectancies
       free_vector(xit,1,n);    Variance-covariance of DFLE
       free_vector(xits,1,n);    prevalence()
       free_vector(ptt,1,n);     movingaverage()
       free_vector(pt,1,n);    varevsij() 
       return;    if popbased==1 varevsij(,popbased)
     }    total life expectancies
     if (*iter == ITMAX) nrerror("powell exceeding maximum iterations.");    Variance of period (stable) prevalence
     for (j=1;j<=n;j++) {   end
       ptt[j]=2.0*p[j]-pt[j];  */
       xit[j]=p[j]-pt[j];  
       pt[j]=p[j];  /* #define DEBUG */
     }  /* #define DEBUGBRENT */
     fptt=(*func)(ptt);  /* #define DEBUGLINMIN */
     if (fptt < fp) {  /* #define DEBUGHESS */
       t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt);  #define DEBUGHESSIJ
       if (t < 0.0) {  /* #define LINMINORIGINAL  /\* Don't use loop on scale in linmin (accepting nan)*\/ */
         linmin(p,xit,n,fret,func);  #define POWELL /* Instead of NLOPT */
         for (j=1;j<=n;j++) {  #define POWELLF1F3 /* Skip test */
           xi[j][ibig]=xi[j][n];  /* #define POWELLORIGINAL /\* Don't use Directest to decide new direction but original Powell test *\/ */
           xi[j][n]=xit[j];  /* #define MNBRAKORIGINAL /\* Don't use mnbrak fix *\/ */
         }  
 #ifdef DEBUG  #include <math.h>
         printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);  #include <stdio.h>
         fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);  #include <stdlib.h>
         for(j=1;j<=n;j++){  #include <string.h>
           printf(" %.12e",xit[j]);  
           fprintf(ficlog," %.12e",xit[j]);  #ifdef _WIN32
         }  #include <io.h>
         printf("\n");  #include <windows.h>
         fprintf(ficlog,"\n");  #include <tchar.h>
 #endif  #else
       }  #include <unistd.h>
     }  #endif
   }  
 }  #include <limits.h>
   #include <sys/types.h>
 /**** Prevalence limit ****************/  
   #if defined(__GNUC__)
 double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int ij)  #include <sys/utsname.h> /* Doesn't work on Windows */
 {  #endif
   /* Computes the prevalence limit in each live state at age x by left multiplying the unit  
      matrix by transitions matrix until convergence is reached */  #include <sys/stat.h>
   #include <errno.h>
   int i, ii,j,k;  /* extern int errno; */
   double min, max, maxmin, maxmax,sumnew=0.;  
   double **matprod2();  /* #ifdef LINUX */
   double **out, cov[NCOVMAX], **pmij();  /* #include <time.h> */
   double **newm;  /* #include "timeval.h" */
   double agefin, delaymax=50 ; /* Max number of years to converge */  /* #else */
   /* #include <sys/time.h> */
   for (ii=1;ii<=nlstate+ndeath;ii++)  /* #endif */
     for (j=1;j<=nlstate+ndeath;j++){  
       oldm[ii][j]=(ii==j ? 1.0 : 0.0);  #include <time.h>
     }  
   #ifdef GSL
    cov[1]=1.;  #include <gsl/gsl_errno.h>
    #include <gsl/gsl_multimin.h>
  /* Even if hstepm = 1, at least one multiplication by the unit matrix */  #endif
   for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){  
     newm=savm;  
     /* Covariates have to be included here again */  #ifdef NLOPT
      cov[2]=agefin;  #include <nlopt.h>
    typedef struct {
       for (k=1; k<=cptcovn;k++) {    double (* function)(double [] );
         cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];  } myfunc_data ;
         /*      printf("ij=%d k=%d Tvar[k]=%d nbcode=%d cov=%lf codtab[ij][Tvar[k]]=%d \n",ij,k, Tvar[k],nbcode[Tvar[k]][codtab[ij][Tvar[k]]],cov[2+k], codtab[ij][Tvar[k]]);*/  #endif
       }  
       for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];  /* #include <libintl.h> */
       for (k=1; k<=cptcovprod;k++)  /* #define _(String) gettext (String) */
         cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];  
   #define MAXLINE 1024 /* Was 256. Overflow with 312 with 2 states and 4 covariates. Should be ok */
       /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/  
       /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/  #define GNUPLOTPROGRAM "gnuplot"
       /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/  /*#define GNUPLOTPROGRAM "..\\gp37mgw\\wgnuplot"*/
     out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm);  #define FILENAMELENGTH 132
   
     savm=oldm;  #define GLOCK_ERROR_NOPATH              -1      /* empty path */
     oldm=newm;  #define GLOCK_ERROR_GETCWD              -2      /* cannot get cwd */
     maxmax=0.;  
     for(j=1;j<=nlstate;j++){  #define MAXPARM 128 /**< Maximum number of parameters for the optimization */
       min=1.;  #define NPARMAX 64 /**< (nlstate+ndeath-1)*nlstate*ncovmodel */
       max=0.;  
       for(i=1; i<=nlstate; i++) {  #define NINTERVMAX 8
         sumnew=0;  #define NLSTATEMAX 8 /**< Maximum number of live states (for func) */
         for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];  #define NDEATHMAX 8 /**< Maximum number of dead states (for func) */
         prlim[i][j]= newm[i][j]/(1-sumnew);  #define NCOVMAX 20 /**< Maximum number of covariates, including generated covariates V1*V2 */
         max=FMAX(max,prlim[i][j]);  #define codtabm(h,k)  (1 & (h-1) >> (k-1))+1
         min=FMIN(min,prlim[i][j]);  #define MAXN 20000
       }  #define YEARM 12. /**< Number of months per year */
       maxmin=max-min;  #define AGESUP 130
       maxmax=FMAX(maxmax,maxmin);  #define AGEBASE 40
     }  #define AGEOVERFLOW 1.e20
     if(maxmax < ftolpl){  #define AGEGOMP 10 /**< Minimal age for Gompertz adjustment */
       return prlim;  #ifdef _WIN32
     }  #define DIRSEPARATOR '\\'
   }  #define CHARSEPARATOR "\\"
 }  #define ODIRSEPARATOR '/'
   #else
 /*************** transition probabilities ***************/  #define DIRSEPARATOR '/'
   #define CHARSEPARATOR "/"
 double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )  #define ODIRSEPARATOR '\\'
 {  #endif
   double s1, s2;  
   /*double t34;*/  /* $Id$ */
   int i,j,j1, nc, ii, jj;  /* $State$ */
   #include "version.h"
     for(i=1; i<= nlstate; i++){  char version[]=__IMACH_VERSION__;
     for(j=1; j<i;j++){  char copyright[]="October 2015,INED-EUROREVES-Institut de longevite-Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research 25293121), Intel Software 2015";
       for (nc=1, s2=0.;nc <=ncovmodel; nc++){  char fullversion[]="$Revision$ $Date$"; 
         /*s2 += param[i][j][nc]*cov[nc];*/  char strstart[80];
         s2 += x[(i-1)*nlstate*ncovmodel+(j-1)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];  char optionfilext[10], optionfilefiname[FILENAMELENGTH];
         /*printf("Int j<i s1=%.17e, s2=%.17e\n",s1,s2);*/  int erreur=0, nberr=0, nbwarn=0; /* Error number, number of errors number of warnings  */
       }  int nagesqr=0, nforce=0; /* nagesqr=1 if model is including age*age, number of forces */
       ps[i][j]=s2;  /* Number of covariates model=V2+V1+ V3*age+V2*V4 */
       /*printf("s1=%.17e, s2=%.17e\n",s1,s2);*/  int cptcovn=0; /**< cptcovn number of covariates added in the model (excepting constant and age and age*product) */
     }  int cptcovt=0; /**< cptcovt number of covariates added in the model (excepting constant and age) */
     for(j=i+1; j<=nlstate+ndeath;j++){  int cptcovs=0; /**< cptcovs number of simple covariates V2+V1 =2 */
       for (nc=1, s2=0.;nc <=ncovmodel; nc++){  int cptcovage=0; /**< Number of covariates with age: V3*age only =1 */
         s2 += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];  int cptcovprodnoage=0; /**< Number of covariate products without age */   
         /*printf("Int j>i s1=%.17e, s2=%.17e %lx %lx\n",s1,s2,s1,s2);*/  int cptcoveff=0; /* Total number of covariates to vary for printing results */
       }  int cptcov=0; /* Working variable */
       ps[i][j]=s2;  int npar=NPARMAX;
     }  int nlstate=2; /* Number of live states */
   }  int ndeath=1; /* Number of dead states */
     /*ps[3][2]=1;*/  int ncovmodel=0, ncovcol=0;     /* Total number of covariables including constant a12*1 +b12*x ncovmodel=2 */
   int popbased=0;
   for(i=1; i<= nlstate; i++){  
      s1=0;  int *wav; /* Number of waves for this individuual 0 is possible */
     for(j=1; j<i; j++)  int maxwav=0; /* Maxim number of waves */
       s1+=exp(ps[i][j]);  int jmin=0, jmax=0; /* min, max spacing between 2 waves */
     for(j=i+1; j<=nlstate+ndeath; j++)  int ijmin=0, ijmax=0; /* Individuals having jmin and jmax */ 
       s1+=exp(ps[i][j]);  int gipmx=0, gsw=0; /* Global variables on the number of contributions 
     ps[i][i]=1./(s1+1.);                     to the likelihood and the sum of weights (done by funcone)*/
     for(j=1; j<i; j++)  int mle=1, weightopt=0;
       ps[i][j]= exp(ps[i][j])*ps[i][i];  int **mw; /* mw[mi][i] is number of the mi wave for this individual */
     for(j=i+1; j<=nlstate+ndeath; j++)  int **dh; /* dh[mi][i] is number of steps between mi,mi+1 for this individual */
       ps[i][j]= exp(ps[i][j])*ps[i][i];  int **bh; /* bh[mi][i] is the bias (+ or -) for this individual if the delay between
     /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */             * wave mi and wave mi+1 is not an exact multiple of stepm. */
   } /* end i */  int countcallfunc=0;  /* Count the number of calls to func */
   double jmean=1; /* Mean space between 2 waves */
   for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){  double **matprod2(); /* test */
     for(jj=1; jj<= nlstate+ndeath; jj++){  double **oldm, **newm, **savm; /* Working pointers to matrices */
       ps[ii][jj]=0;  double **oldms, **newms, **savms; /* Fixed working pointers to matrices */
       ps[ii][ii]=1;  /*FILE *fic ; */ /* Used in readdata only */
     }  FILE *ficpar, *ficparo,*ficres, *ficresp, *ficrespl, *ficrespij, *ficrest,*ficresf,*ficrespop;
   }  FILE *ficlog, *ficrespow;
   int globpr=0; /* Global variable for printing or not */
   double fretone; /* Only one call to likelihood */
   /*   for(ii=1; ii<= nlstate+ndeath; ii++){  long ipmx=0; /* Number of contributions */
     for(jj=1; jj<= nlstate+ndeath; jj++){  double sw; /* Sum of weights */
      printf("%lf ",ps[ii][jj]);  char filerespow[FILENAMELENGTH];
    }  char fileresilk[FILENAMELENGTH]; /* File of individual contributions to the likelihood */
     printf("\n ");  FILE *ficresilk;
     }  FILE *ficgp,*ficresprob,*ficpop, *ficresprobcov, *ficresprobcor;
     printf("\n ");printf("%lf ",cov[2]);*/  FILE *ficresprobmorprev;
 /*  FILE *fichtm, *fichtmcov; /* Html File */
   for(i=1; i<= npar; i++) printf("%f ",x[i]);  FILE *ficreseij;
   goto end;*/  char filerese[FILENAMELENGTH];
     return ps;  FILE *ficresstdeij;
 }  char fileresstde[FILENAMELENGTH];
   FILE *ficrescveij;
 /**************** Product of 2 matrices ******************/  char filerescve[FILENAMELENGTH];
   FILE  *ficresvij;
 double **matprod2(double **out, double **in,long nrl, long nrh, long ncl, long nch, long ncolol, long ncoloh, double **b)  char fileresv[FILENAMELENGTH];
 {  FILE  *ficresvpl;
   /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times  char fileresvpl[FILENAMELENGTH];
      b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */  char title[MAXLINE];
   /* in, b, out are matrice of pointers which should have been initialized  char optionfile[FILENAMELENGTH], datafile[FILENAMELENGTH],  filerespl[FILENAMELENGTH];
      before: only the contents of out is modified. The function returns  char plotcmd[FILENAMELENGTH], pplotcmd[FILENAMELENGTH];
      a pointer to pointers identical to out */  char tmpout[FILENAMELENGTH],  tmpout2[FILENAMELENGTH]; 
   long i, j, k;  char command[FILENAMELENGTH];
   for(i=nrl; i<= nrh; i++)  int  outcmd=0;
     for(k=ncolol; k<=ncoloh; k++)  
       for(j=ncl,out[i][k]=0.; j<=nch; j++)  char fileres[FILENAMELENGTH], filerespij[FILENAMELENGTH], filereso[FILENAMELENGTH], rfileres[FILENAMELENGTH];
         out[i][k] +=in[i][j]*b[j][k];  char fileresu[FILENAMELENGTH]; /* fileres without r in front */
   char filelog[FILENAMELENGTH]; /* Log file */
   return out;  char filerest[FILENAMELENGTH];
 }  char fileregp[FILENAMELENGTH];
   char popfile[FILENAMELENGTH];
   
 /************* Higher Matrix Product ***************/  char optionfilegnuplot[FILENAMELENGTH], optionfilehtm[FILENAMELENGTH], optionfilehtmcov[FILENAMELENGTH] ;
   
 double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )  /* struct timeval start_time, end_time, curr_time, last_time, forecast_time; */
 {  /* struct timezone tzp; */
   /* Computes the transition matrix starting at age 'age' over 'nhstepm*hstepm*stepm' month  /* extern int gettimeofday(); */
      duration (i.e. until  struct tm tml, *gmtime(), *localtime();
      age (in years)  age+nhstepm*stepm/12) by multiplying nhstepm*hstepm matrices.  
      Output is stored in matrix po[i][j][h] for h every 'hstepm' step  extern time_t time();
      (typically every 2 years instead of every month which is too big).  
      Model is determined by parameters x and covariates have to be  struct tm start_time, end_time, curr_time, last_time, forecast_time;
      included manually here.  time_t  rstart_time, rend_time, rcurr_time, rlast_time, rforecast_time; /* raw time */
   struct tm tm;
      */  
   char strcurr[80], strfor[80];
   int i, j, d, h, k;  
   double **out, cov[NCOVMAX];  char *endptr;
   double **newm;  long lval;
   double dval;
   /* Hstepm could be zero and should return the unit matrix */  
   for (i=1;i<=nlstate+ndeath;i++)  #define NR_END 1
     for (j=1;j<=nlstate+ndeath;j++){  #define FREE_ARG char*
       oldm[i][j]=(i==j ? 1.0 : 0.0);  #define FTOL 1.0e-10
       po[i][j][0]=(i==j ? 1.0 : 0.0);  
     }  #define NRANSI 
   /* Even if hstepm = 1, at least one multiplication by the unit matrix */  #define ITMAX 200 
   for(h=1; h <=nhstepm; h++){  
     for(d=1; d <=hstepm; d++){  #define TOL 2.0e-4 
       newm=savm;  
       /* Covariates have to be included here again */  #define CGOLD 0.3819660 
       cov[1]=1.;  #define ZEPS 1.0e-10 
       cov[2]=age+((h-1)*hstepm + (d-1))*stepm/YEARM;  #define SHFT(a,b,c,d) (a)=(b);(b)=(c);(c)=(d); 
       for (k=1; k<=cptcovn;k++) cov[2+k]=nbcode[Tvar[k]][codtab[ij][Tvar[k]]];  
       for (k=1; k<=cptcovage;k++)  #define GOLD 1.618034 
         cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];  #define GLIMIT 100.0 
       for (k=1; k<=cptcovprod;k++)  #define TINY 1.0e-20 
         cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];  
   static double maxarg1,maxarg2;
   #define FMAX(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)>(maxarg2)? (maxarg1):(maxarg2))
       /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/  #define FMIN(a,b) (maxarg1=(a),maxarg2=(b),(maxarg1)<(maxarg2)? (maxarg1):(maxarg2))
       /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/    
       out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath,  #define SIGN(a,b) ((b)>0.0 ? fabs(a) : -fabs(a))
                    pmij(pmmij,cov,ncovmodel,x,nlstate));  #define rint(a) floor(a+0.5)
       savm=oldm;  /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/myutils_8h-source.html */
       oldm=newm;  #define mytinydouble 1.0e-16
     }  /* #define DEQUAL(a,b) (fabs((a)-(b))<mytinydouble) */
     for(i=1; i<=nlstate+ndeath; i++)  /* http://www.thphys.uni-heidelberg.de/~robbers/cmbeasy/doc/html/mynrutils_8h-source.html */
       for(j=1;j<=nlstate+ndeath;j++) {  /* static double dsqrarg; */
         po[i][j][h]=newm[i][j];  /* #define DSQR(a) (DEQUAL((dsqrarg=(a)),0.0) ? 0.0 : dsqrarg*dsqrarg) */
         /*printf("i=%d j=%d h=%d po[i][j][h]=%f ",i,j,h,po[i][j][h]);  static double sqrarg;
          */  #define SQR(a) ((sqrarg=(a)) == 0.0 ? 0.0 :sqrarg*sqrarg)
       }  #define SWAP(a,b) {temp=(a);(a)=(b);(b)=temp;} 
   } /* end h */  int agegomp= AGEGOMP;
   return po;  
 }  int imx; 
   int stepm=1;
   /* Stepm, step in month: minimum step interpolation*/
 /*************** log-likelihood *************/  
 double func( double *x)  int estepm;
 {  /* Estepm, step in month to interpolate survival function in order to approximate Life Expectancy*/
   int i, ii, j, k, mi, d, kk;  
   double l, ll[NLSTATEMAX], cov[NCOVMAX];  int m,nb;
   double **out;  long *num;
   double sw; /* Sum of weights */  int firstpass=0, lastpass=4,*cod, *cens;
   double lli; /* Individual log likelihood */  int *ncodemax;  /* ncodemax[j]= Number of modalities of the j th
   long ipmx;                     covariate for which somebody answered excluding 
   /*extern weight */                     undefined. Usually 2: 0 and 1. */
   /* We are differentiating ll according to initial status */  int *ncodemaxwundef;  /* ncodemax[j]= Number of modalities of the j th
   /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/                               covariate for which somebody answered including 
   /*for(i=1;i<imx;i++)                               undefined. Usually 3: -1, 0 and 1. */
     printf(" %d\n",s[4][i]);  double **agev,*moisnais, *annais, *moisdc, *andc,**mint, **anint;
   */  double **pmmij, ***probs;
   cov[1]=1.;  double *ageexmed,*agecens;
   double dateintmean=0;
   for(k=1; k<=nlstate; k++) ll[k]=0.;  
   for (i=1,ipmx=0, sw=0.; i<=imx; i++){  double *weight;
     for (k=1; k<=cptcovn;k++) cov[2+k]=covar[Tvar[k]][i];  int **s; /* Status */
     for(mi=1; mi<= wav[i]-1; mi++){  double *agedc;
       for (ii=1;ii<=nlstate+ndeath;ii++)  double  **covar; /**< covar[j,i], value of jth covariate for individual i,
         for (j=1;j<=nlstate+ndeath;j++) oldm[ii][j]=(ii==j ? 1.0 : 0.0);                    * covar=matrix(0,NCOVMAX,1,n); 
       for(d=0; d<dh[mi][i]; d++){                    * cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*age; */
         newm=savm;  double  idx; 
         cov[2]=agev[mw[mi][i]][i]+d*stepm/YEARM;  int **nbcode, *Tvar; /**< model=V2 => Tvar[1]= 2 */
         for (kk=1; kk<=cptcovage;kk++) {  int *Tage;
           cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];  int *Ndum; /** Freq of modality (tricode */
         }  /* int **codtab;*/ /**< codtab=imatrix(1,100,1,10); */
          int **Tvard, *Tprod, cptcovprod, *Tvaraff;
         out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,  double *lsurv, *lpop, *tpop;
                      1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));  
         savm=oldm;  double ftol=FTOL; /**< Tolerance for computing Max Likelihood */
         oldm=newm;  double ftolhess; /**< Tolerance for computing hessian */
          
          /**************** split *************************/
       } /* end mult */  static  int split( char *path, char *dirc, char *name, char *ext, char *finame )
        {
       lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);    /* From a file name with (full) path (either Unix or Windows) we extract the directory (dirc)
       /* printf(" %f ",out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/       the name of the file (name), its extension only (ext) and its first part of the name (finame)
       ipmx +=1;    */ 
       sw += weight[i];    char  *ss;                            /* pointer */
       ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;    int   l1=0, l2=0;                             /* length counters */
     } /* end of wave */  
   } /* end of individual */    l1 = strlen(path );                   /* length of path */
     if ( l1 == 0 ) return( GLOCK_ERROR_NOPATH );
   for(k=1,l=0.; k<=nlstate; k++) l += ll[k];    ss= strrchr( path, DIRSEPARATOR );            /* find last / */
   /* printf("l1=%f l2=%f ",ll[1],ll[2]); */    if ( ss == NULL ) {                   /* no directory, so determine current directory */
   l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */      strcpy( name, path );               /* we got the fullname name because no directory */
   return -l;      /*if(strrchr(path, ODIRSEPARATOR )==NULL)
 }        printf("Warning you should use %s as a separator\n",DIRSEPARATOR);*/
       /* get current working directory */
       /*    extern  char* getcwd ( char *buf , int len);*/
 /*********** Maximum Likelihood Estimation ***************/  #ifdef WIN32
       if (_getcwd( dirc, FILENAME_MAX ) == NULL ) {
 void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))  #else
 {          if (getcwd(dirc, FILENAME_MAX) == NULL) {
   int i,j, iter;  #endif
   double **xi,*delti;        return( GLOCK_ERROR_GETCWD );
   double fret;      }
   xi=matrix(1,npar,1,npar);      /* got dirc from getcwd*/
   for (i=1;i<=npar;i++)      printf(" DIRC = %s \n",dirc);
     for (j=1;j<=npar;j++)    } else {                              /* strip directory from path */
       xi[i][j]=(i==j ? 1.0 : 0.0);      ss++;                               /* after this, the filename */
   printf("Powell\n");  fprintf(ficlog,"Powell\n");      l2 = strlen( ss );                  /* length of filename */
   powell(p,xi,npar,ftol,&iter,&fret,func);      if ( l2 == 0 ) return( GLOCK_ERROR_NOPATH );
       strcpy( name, ss );         /* save file name */
    printf("\n#Number of iterations = %d, -2 Log likelihood = %.12f\n",iter,func(p));      strncpy( dirc, path, l1 - l2 );     /* now the directory */
   fprintf(ficlog,"#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));      dirc[l1-l2] = '\0';                 /* add zero */
   fprintf(ficres,"#Number of iterations = %d, -2 Log likelihood = %.12f \n",iter,func(p));      printf(" DIRC2 = %s \n",dirc);
     }
 }    /* We add a separator at the end of dirc if not exists */
     l1 = strlen( dirc );                  /* length of directory */
 /**** Computes Hessian and covariance matrix ***/    if( dirc[l1-1] != DIRSEPARATOR ){
 void hesscov(double **matcov, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))      dirc[l1] =  DIRSEPARATOR;
 {      dirc[l1+1] = 0; 
   double  **a,**y,*x,pd;      printf(" DIRC3 = %s \n",dirc);
   double **hess;    }
   int i, j,jk;    ss = strrchr( name, '.' );            /* find last / */
   int *indx;    if (ss >0){
       ss++;
   double hessii(double p[], double delta, int theta, double delti[]);      strcpy(ext,ss);                     /* save extension */
   double hessij(double p[], double delti[], int i, int j);      l1= strlen( name);
   void lubksb(double **a, int npar, int *indx, double b[]) ;      l2= strlen(ss)+1;
   void ludcmp(double **a, int npar, int *indx, double *d) ;      strncpy( finame, name, l1-l2);
       finame[l1-l2]= 0;
   hess=matrix(1,npar,1,npar);    }
   
   printf("\nCalculation of the hessian matrix. Wait...\n");    return( 0 );                          /* we're done */
   fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");  }
   for (i=1;i<=npar;i++){  
     printf("%d",i);fflush(stdout);  
     fprintf(ficlog,"%d",i);fflush(ficlog);  /******************************************/
     hess[i][i]=hessii(p,ftolhess,i,delti);  
     /*printf(" %f ",p[i]);*/  void replace_back_to_slash(char *s, char*t)
     /*printf(" %lf ",hess[i][i]);*/  {
   }    int i;
      int lg=0;
   for (i=1;i<=npar;i++) {    i=0;
     for (j=1;j<=npar;j++)  {    lg=strlen(t);
       if (j>i) {    for(i=0; i<= lg; i++) {
         printf(".%d%d",i,j);fflush(stdout);      (s[i] = t[i]);
         fprintf(ficlog,".%d%d",i,j);fflush(ficlog);      if (t[i]== '\\') s[i]='/';
         hess[i][j]=hessij(p,delti,i,j);    }
         hess[j][i]=hess[i][j];      }
         /*printf(" %lf ",hess[i][j]);*/  
       }  char *trimbb(char *out, char *in)
     }  { /* Trim multiple blanks in line but keeps first blanks if line starts with blanks */
   }    char *s;
   printf("\n");    s=out;
   fprintf(ficlog,"\n");    while (*in != '\0'){
       while( *in == ' ' && *(in+1) == ' '){ /* && *(in+1) != '\0'){*/
   printf("\nInverting the hessian to get the covariance matrix. Wait...\n");        in++;
   fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");      }
        *out++ = *in++;
   a=matrix(1,npar,1,npar);    }
   y=matrix(1,npar,1,npar);    *out='\0';
   x=vector(1,npar);    return s;
   indx=ivector(1,npar);  }
   for (i=1;i<=npar;i++)  
     for (j=1;j<=npar;j++) a[i][j]=hess[i][j];  /* char *substrchaine(char *out, char *in, char *chain) */
   ludcmp(a,npar,indx,&pd);  /* { */
   /*   /\* Substract chain 'chain' from 'in', return and output 'out' *\/ */
   for (j=1;j<=npar;j++) {  /*   char *s, *t; */
     for (i=1;i<=npar;i++) x[i]=0;  /*   t=in;s=out; */
     x[j]=1;  /*   while ((*in != *chain) && (*in != '\0')){ */
     lubksb(a,npar,indx,x);  /*     *out++ = *in++; */
     for (i=1;i<=npar;i++){  /*   } */
       matcov[i][j]=x[i];  
     }  /*   /\* *in matches *chain *\/ */
   }  /*   while ((*in++ == *chain++) && (*in != '\0')){ */
   /*     printf("*in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
   printf("\n#Hessian matrix#\n");  /*   } */
   fprintf(ficlog,"\n#Hessian matrix#\n");  /*   in--; chain--; */
   for (i=1;i<=npar;i++) {  /*   while ( (*in != '\0')){ */
     for (j=1;j<=npar;j++) {  /*     printf("Bef *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
       printf("%.3e ",hess[i][j]);  /*     *out++ = *in++; */
       fprintf(ficlog,"%.3e ",hess[i][j]);  /*     printf("Aft *in = %c, *out= %c *chain= %c \n", *in, *out, *chain);  */
     }  /*   } */
     printf("\n");  /*   *out='\0'; */
     fprintf(ficlog,"\n");  /*   out=s; */
   }  /*   return out; */
   /* } */
   /* Recompute Inverse */  char *substrchaine(char *out, char *in, char *chain)
   for (i=1;i<=npar;i++)  {
     for (j=1;j<=npar;j++) a[i][j]=matcov[i][j];    /* Substract chain 'chain' from 'in', return and output 'out' */
   ludcmp(a,npar,indx,&pd);    /* in="V1+V1*age+age*age+V2", chain="age*age" */
   
   /*  printf("\n#Hessian matrix recomputed#\n");    char *strloc;
   
   for (j=1;j<=npar;j++) {    strcpy (out, in); 
     for (i=1;i<=npar;i++) x[i]=0;    strloc = strstr(out, chain); /* strloc points to out at age*age+V2 */
     x[j]=1;    printf("Bef strloc=%s chain=%s out=%s \n", strloc, chain, out);
     lubksb(a,npar,indx,x);    if(strloc != NULL){ 
     for (i=1;i<=npar;i++){      /* will affect out */ /* strloc+strlenc(chain)=+V2 */ /* Will also work in Unicode */
       y[i][j]=x[i];      memmove(strloc,strloc+strlen(chain), strlen(strloc+strlen(chain))+1);
       printf("%.3e ",y[i][j]);      /* strcpy (strloc, strloc +strlen(chain));*/
       fprintf(ficlog,"%.3e ",y[i][j]);    }
     }    printf("Aft strloc=%s chain=%s in=%s out=%s \n", strloc, chain, in, out);
     printf("\n");    return out;
     fprintf(ficlog,"\n");  }
   }  
   */  
   char *cutl(char *blocc, char *alocc, char *in, char occ)
   free_matrix(a,1,npar,1,npar);  {
   free_matrix(y,1,npar,1,npar);    /* cuts string in into blocc and alocc where blocc ends before FIRST occurence of char 'occ' 
   free_vector(x,1,npar);       and alocc starts after first occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
   free_ivector(indx,1,npar);       gives blocc="abcdef" and alocc="ghi2j".
   free_matrix(hess,1,npar,1,npar);       If occ is not found blocc is null and alocc is equal to in. Returns blocc
     */
     char *s, *t;
 }    t=in;s=in;
     while ((*in != occ) && (*in != '\0')){
 /*************** hessian matrix ****************/      *alocc++ = *in++;
 double hessii( double x[], double delta, int theta, double delti[])    }
 {    if( *in == occ){
   int i;      *(alocc)='\0';
   int l=1, lmax=20;      s=++in;
   double k1,k2;    }
   double p2[NPARMAX+1];   
   double res;    if (s == t) {/* occ not found */
   double delt, delts, nkhi=10.,nkhif=1., khi=1.e-4;      *(alocc-(in-s))='\0';
   double fx;      in=s;
   int k=0,kmax=10;    }
   double l1;    while ( *in != '\0'){
       *blocc++ = *in++;
   fx=func(x);    }
   for (i=1;i<=npar;i++) p2[i]=x[i];  
   for(l=0 ; l <=lmax; l++){    *blocc='\0';
     l1=pow(10,l);    return t;
     delts=delt;  }
     for(k=1 ; k <kmax; k=k+1){  char *cutv(char *blocc, char *alocc, char *in, char occ)
       delt = delta*(l1*k);  {
       p2[theta]=x[theta] +delt;    /* cuts string in into blocc and alocc where blocc ends before LAST occurence of char 'occ' 
       k1=func(p2)-fx;       and alocc starts after last occurence of char 'occ' : ex cutv(blocc,alocc,"abcdef2ghi2j",'2')
       p2[theta]=x[theta]-delt;       gives blocc="abcdef2ghi" and alocc="j".
       k2=func(p2)-fx;       If occ is not found blocc is null and alocc is equal to in. Returns alocc
       /*res= (k1-2.0*fx+k2)/delt/delt; */    */
       res= (k1+k2)/delt/delt/2.; /* Divided by because L and not 2*L */    char *s, *t;
          t=in;s=in;
 #ifdef DEBUG    while (*in != '\0'){
       printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);      while( *in == occ){
       fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);        *blocc++ = *in++;
 #endif        s=in;
       /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */      }
       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){      *blocc++ = *in++;
         k=kmax;    }
       }    if (s == t) /* occ not found */
       else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */      *(blocc-(in-s))='\0';
         k=kmax; l=lmax*10.;    else
       }      *(blocc-(in-s)-1)='\0';
       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){    in=s;
         delts=delt;    while ( *in != '\0'){
       }      *alocc++ = *in++;
     }    }
   }  
   delti[theta]=delts;    *alocc='\0';
   return res;    return s;
    }
 }  
   int nbocc(char *s, char occ)
 double hessij( double x[], double delti[], int thetai,int thetaj)  {
 {    int i,j=0;
   int i;    int lg=20;
   int l=1, l1, lmax=20;    i=0;
   double k1,k2,k3,k4,res,fx;    lg=strlen(s);
   double p2[NPARMAX+1];    for(i=0; i<= lg; i++) {
   int k;    if  (s[i] == occ ) j++;
     }
   fx=func(x);    return j;
   for (k=1; k<=2; k++) {  }
     for (i=1;i<=npar;i++) p2[i]=x[i];  
     p2[thetai]=x[thetai]+delti[thetai]/k;  /* void cutv(char *u,char *v, char*t, char occ) */
     p2[thetaj]=x[thetaj]+delti[thetaj]/k;  /* { */
     k1=func(p2)-fx;  /*   /\* cuts string t into u and v where u ends before last occurence of char 'occ'  */
    /*      and v starts after last occurence of char 'occ' : ex cutv(u,v,"abcdef2ghi2j",'2') */
     p2[thetai]=x[thetai]+delti[thetai]/k;  /*      gives u="abcdef2ghi" and v="j" *\/ */
     p2[thetaj]=x[thetaj]-delti[thetaj]/k;  /*   int i,lg,j,p=0; */
     k2=func(p2)-fx;  /*   i=0; */
    /*   lg=strlen(t); */
     p2[thetai]=x[thetai]-delti[thetai]/k;  /*   for(j=0; j<=lg-1; j++) { */
     p2[thetaj]=x[thetaj]+delti[thetaj]/k;  /*     if((t[j]!= occ) && (t[j+1]== occ)) p=j+1; */
     k3=func(p2)-fx;  /*   } */
    
     p2[thetai]=x[thetai]-delti[thetai]/k;  /*   for(j=0; j<p; j++) { */
     p2[thetaj]=x[thetaj]-delti[thetaj]/k;  /*     (u[j] = t[j]); */
     k4=func(p2)-fx;  /*   } */
     res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /* Because of L not 2*L */  /*      u[p]='\0'; */
 #ifdef DEBUG  
     printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);  /*    for(j=0; j<= lg; j++) { */
     fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);  /*     if (j>=(p+1))(v[j-p-1] = t[j]); */
 #endif  /*   } */
   }  /* } */
   return res;  
 }  #ifdef _WIN32
   char * strsep(char **pp, const char *delim)
 /************** Inverse of matrix **************/  {
 void ludcmp(double **a, int n, int *indx, double *d)    char *p, *q;
 {           
   int i,imax,j,k;    if ((p = *pp) == NULL)
   double big,dum,sum,temp;      return 0;
   double *vv;    if ((q = strpbrk (p, delim)) != NULL)
      {
   vv=vector(1,n);      *pp = q + 1;
   *d=1.0;      *q = '\0';
   for (i=1;i<=n;i++) {    }
     big=0.0;    else
     for (j=1;j<=n;j++)      *pp = 0;
       if ((temp=fabs(a[i][j])) > big) big=temp;    return p;
     if (big == 0.0) nrerror("Singular matrix in routine ludcmp");  }
     vv[i]=1.0/big;  #endif
   }  
   for (j=1;j<=n;j++) {  /********************** nrerror ********************/
     for (i=1;i<j;i++) {  
       sum=a[i][j];  void nrerror(char error_text[])
       for (k=1;k<i;k++) sum -= a[i][k]*a[k][j];  {
       a[i][j]=sum;    fprintf(stderr,"ERREUR ...\n");
     }    fprintf(stderr,"%s\n",error_text);
     big=0.0;    exit(EXIT_FAILURE);
     for (i=j;i<=n;i++) {  }
       sum=a[i][j];  /*********************** vector *******************/
       for (k=1;k<j;k++)  double *vector(int nl, int nh)
         sum -= a[i][k]*a[k][j];  {
       a[i][j]=sum;    double *v;
       if ( (dum=vv[i]*fabs(sum)) >= big) {    v=(double *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(double)));
         big=dum;    if (!v) nrerror("allocation failure in vector");
         imax=i;    return v-nl+NR_END;
       }  }
     }  
     if (j != imax) {  /************************ free vector ******************/
       for (k=1;k<=n;k++) {  void free_vector(double*v, int nl, int nh)
         dum=a[imax][k];  {
         a[imax][k]=a[j][k];    free((FREE_ARG)(v+nl-NR_END));
         a[j][k]=dum;  }
       }  
       *d = -(*d);  /************************ivector *******************************/
       vv[imax]=vv[j];  int *ivector(long nl,long nh)
     }  {
     indx[j]=imax;    int *v;
     if (a[j][j] == 0.0) a[j][j]=TINY;    v=(int *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(int)));
     if (j != n) {    if (!v) nrerror("allocation failure in ivector");
       dum=1.0/(a[j][j]);    return v-nl+NR_END;
       for (i=j+1;i<=n;i++) a[i][j] *= dum;  }
     }  
   }  /******************free ivector **************************/
   free_vector(vv,1,n);  /* Doesn't work */  void free_ivector(int *v, long nl, long nh)
 ;  {
 }    free((FREE_ARG)(v+nl-NR_END));
   }
 void lubksb(double **a, int n, int *indx, double b[])  
 {  /************************lvector *******************************/
   int i,ii=0,ip,j;  long *lvector(long nl,long nh)
   double sum;  {
      long *v;
   for (i=1;i<=n;i++) {    v=(long *) malloc((size_t)((nh-nl+1+NR_END)*sizeof(long)));
     ip=indx[i];    if (!v) nrerror("allocation failure in ivector");
     sum=b[ip];    return v-nl+NR_END;
     b[ip]=b[i];  }
     if (ii)  
       for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j];  /******************free lvector **************************/
     else if (sum) ii=i;  void free_lvector(long *v, long nl, long nh)
     b[i]=sum;  {
   }    free((FREE_ARG)(v+nl-NR_END));
   for (i=n;i>=1;i--) {  }
     sum=b[i];  
     for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j];  /******************* imatrix *******************************/
     b[i]=sum/a[i][i];  int **imatrix(long nrl, long nrh, long ncl, long nch) 
   }       /* allocate a int matrix with subscript range m[nrl..nrh][ncl..nch] */ 
 }  { 
     long i, nrow=nrh-nrl+1,ncol=nch-ncl+1; 
 /************ Frequencies ********************/    int **m; 
 void  freqsummary(char fileres[], int agemin, int agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2,double jprev1, double mprev1,double anprev1,double jprev2, double mprev2,double anprev2)    
 {  /* Some frequencies */    /* allocate pointers to rows */ 
      m=(int **) malloc((size_t)((nrow+NR_END)*sizeof(int*))); 
   int i, m, jk, k1,i1, j1, bool, z1,z2,j;    if (!m) nrerror("allocation failure 1 in matrix()"); 
   int first;    m += NR_END; 
   double ***freq; /* Frequencies */    m -= nrl; 
   double *pp;    
   double pos, k2, dateintsum=0,k2cpt=0;    
   FILE *ficresp;    /* allocate rows and set pointers to them */ 
   char fileresp[FILENAMELENGTH];    m[nrl]=(int *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(int))); 
      if (!m[nrl]) nrerror("allocation failure 2 in matrix()"); 
   pp=vector(1,nlstate);    m[nrl] += NR_END; 
   probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);    m[nrl] -= ncl; 
   strcpy(fileresp,"p");    
   strcat(fileresp,fileres);    for(i=nrl+1;i<=nrh;i++) m[i]=m[i-1]+ncol; 
   if((ficresp=fopen(fileresp,"w"))==NULL) {    
     printf("Problem with prevalence resultfile: %s\n", fileresp);    /* return pointer to array of pointers to rows */ 
     fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);    return m; 
     exit(0);  } 
   }  
   freq= ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,agemin,agemax+3);  /****************** free_imatrix *************************/
   j1=0;  void free_imatrix(m,nrl,nrh,ncl,nch)
          int **m;
   j=cptcoveff;        long nch,ncl,nrh,nrl; 
   if (cptcovn<1) {j=1;ncodemax[1]=1;}       /* free an int matrix allocated by imatrix() */ 
   { 
   first=1;    free((FREE_ARG) (m[nrl]+ncl-NR_END)); 
     free((FREE_ARG) (m+nrl-NR_END)); 
   for(k1=1; k1<=j;k1++){  } 
     for(i1=1; i1<=ncodemax[k1];i1++){  
       j1++;  /******************* matrix *******************************/
       /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);  double **matrix(long nrl, long nrh, long ncl, long nch)
         scanf("%d", i);*/  {
       for (i=-1; i<=nlstate+ndeath; i++)      long i, nrow=nrh-nrl+1, ncol=nch-ncl+1;
         for (jk=-1; jk<=nlstate+ndeath; jk++)      double **m;
           for(m=agemin; m <= agemax+3; m++)  
             freq[i][jk][m]=0;    m=(double **) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
          if (!m) nrerror("allocation failure 1 in matrix()");
       dateintsum=0;    m += NR_END;
       k2cpt=0;    m -= nrl;
       for (i=1; i<=imx; i++) {  
         bool=1;    m[nrl]=(double *) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
         if  (cptcovn>0) {    if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
           for (z1=1; z1<=cptcoveff; z1++)    m[nrl] += NR_END;
             if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]])    m[nrl] -= ncl;
               bool=0;  
         }    for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
         if (bool==1) {    return m;
           for(m=firstpass; m<=lastpass; m++){    /* print *(*(m+1)+70) or print m[1][70]; print m+1 or print &(m[1]) or &(m[1][0])
             k2=anint[m][i]+(mint[m][i]/12.);  m[i] = address of ith row of the table. &(m[i]) is its value which is another adress
             if ((k2>=dateprev1) && (k2<=dateprev2)) {  that of m[i][0]. In order to get the value p m[i][0] but it is unitialized.
               if(agev[m][i]==0) agev[m][i]=agemax+1;     */
               if(agev[m][i]==1) agev[m][i]=agemax+2;  }
               if (m<lastpass) {  
                 freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];  /*************************free matrix ************************/
                 freq[s[m][i]][s[m+1][i]][(int) agemax+3] += weight[i];  void free_matrix(double **m, long nrl, long nrh, long ncl, long nch)
               }  {
                  free((FREE_ARG)(m[nrl]+ncl-NR_END));
               if ((agev[m][i]>1) && (agev[m][i]< (agemax+3))) {    free((FREE_ARG)(m+nrl-NR_END));
                 dateintsum=dateintsum+k2;  }
                 k2cpt++;  
               }  /******************* ma3x *******************************/
             }  double ***ma3x(long nrl, long nrh, long ncl, long nch, long nll, long nlh)
           }  {
         }    long i, j, nrow=nrh-nrl+1, ncol=nch-ncl+1, nlay=nlh-nll+1;
       }    double ***m;
          
       fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);    m=(double ***) malloc((size_t)((nrow+NR_END)*sizeof(double*)));
     if (!m) nrerror("allocation failure 1 in matrix()");
       if  (cptcovn>0) {    m += NR_END;
         fprintf(ficresp, "\n#********** Variable ");    m -= nrl;
         for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);  
         fprintf(ficresp, "**********\n#");    m[nrl]=(double **) malloc((size_t)((nrow*ncol+NR_END)*sizeof(double)));
       }    if (!m[nrl]) nrerror("allocation failure 2 in matrix()");
       for(i=1; i<=nlstate;i++)    m[nrl] += NR_END;
         fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);    m[nrl] -= ncl;
       fprintf(ficresp, "\n");  
          for (i=nrl+1; i<=nrh; i++) m[i]=m[i-1]+ncol;
       for(i=(int)agemin; i <= (int)agemax+3; i++){  
         if(i==(int)agemax+3){    m[nrl][ncl]=(double *) malloc((size_t)((nrow*ncol*nlay+NR_END)*sizeof(double)));
           fprintf(ficlog,"Total");    if (!m[nrl][ncl]) nrerror("allocation failure 3 in matrix()");
         }else{    m[nrl][ncl] += NR_END;
           if(first==1){    m[nrl][ncl] -= nll;
             first=0;    for (j=ncl+1; j<=nch; j++) 
             printf("See log file for details...\n");      m[nrl][j]=m[nrl][j-1]+nlay;
           }    
           fprintf(ficlog,"Age %d", i);    for (i=nrl+1; i<=nrh; i++) {
         }      m[i][ncl]=m[i-1l][ncl]+ncol*nlay;
         for(jk=1; jk <=nlstate ; jk++){      for (j=ncl+1; j<=nch; j++) 
           for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)        m[i][j]=m[i][j-1]+nlay;
             pp[jk] += freq[jk][m][i];    }
         }    return m; 
         for(jk=1; jk <=nlstate ; jk++){    /*  gdb: p *(m+1) <=> p m[1] and p (m+1) <=> p (m+1) <=> p &(m[1])
           for(m=-1, pos=0; m <=0 ; m++)             &(m[i][j][k]) <=> *((*(m+i) + j)+k)
             pos += freq[jk][m][i];    */
           if(pp[jk]>=1.e-10){  }
             if(first==1){  
             printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);  /*************************free ma3x ************************/
             }  void free_ma3x(double ***m, long nrl, long nrh, long ncl, long nch,long nll, long nlh)
             fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);  {
           }else{    free((FREE_ARG)(m[nrl][ncl]+ nll-NR_END));
             if(first==1)    free((FREE_ARG)(m[nrl]+ncl-NR_END));
               printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);    free((FREE_ARG)(m+nrl-NR_END));
             fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);  }
           }  
         }  /*************** function subdirf ***********/
   char *subdirf(char fileres[])
         for(jk=1; jk <=nlstate ; jk++){  {
           for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)    /* Caution optionfilefiname is hidden */
             pp[jk] += freq[jk][m][i];    strcpy(tmpout,optionfilefiname);
         }    strcat(tmpout,"/"); /* Add to the right */
     strcat(tmpout,fileres);
         for(jk=1,pos=0; jk <=nlstate ; jk++)    return tmpout;
           pos += pp[jk];  }
         for(jk=1; jk <=nlstate ; jk++){  
           if(pos>=1.e-5){  /*************** function subdirf2 ***********/
             if(first==1)  char *subdirf2(char fileres[], char *preop)
               printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);  {
             fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);    
           }else{    /* Caution optionfilefiname is hidden */
             if(first==1)    strcpy(tmpout,optionfilefiname);
               printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);    strcat(tmpout,"/");
             fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);    strcat(tmpout,preop);
           }    strcat(tmpout,fileres);
           if( i <= (int) agemax){    return tmpout;
             if(pos>=1.e-5){  }
               fprintf(ficresp," %d %.5f %.0f %.0f",i,pp[jk]/pos, pp[jk],pos);  
               probs[i][jk][j1]= pp[jk]/pos;  /*************** function subdirf3 ***********/
               /*printf("\ni=%d jk=%d j1=%d %.5f %.0f %.0f %f",i,jk,j1,pp[jk]/pos, pp[jk],pos,probs[i][jk][j1]);*/  char *subdirf3(char fileres[], char *preop, char *preop2)
             }  {
             else    
               fprintf(ficresp," %d NaNq %.0f %.0f",i,pp[jk],pos);    /* Caution optionfilefiname is hidden */
           }    strcpy(tmpout,optionfilefiname);
         }    strcat(tmpout,"/");
            strcat(tmpout,preop);
         for(jk=-1; jk <=nlstate+ndeath; jk++)    strcat(tmpout,preop2);
           for(m=-1; m <=nlstate+ndeath; m++)    strcat(tmpout,fileres);
             if(freq[jk][m][i] !=0 ) {    return tmpout;
             if(first==1)  }
               printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);  
               fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][i]);  char *asc_diff_time(long time_sec, char ascdiff[])
             }  {
         if(i <= (int) agemax)    long sec_left, days, hours, minutes;
           fprintf(ficresp,"\n");    days = (time_sec) / (60*60*24);
         if(first==1)    sec_left = (time_sec) % (60*60*24);
           printf("Others in log...\n");    hours = (sec_left) / (60*60) ;
         fprintf(ficlog,"\n");    sec_left = (sec_left) %(60*60);
       }    minutes = (sec_left) /60;
     }    sec_left = (sec_left) % (60);
   }    sprintf(ascdiff,"%ld day(s) %ld hour(s) %ld minute(s) %ld second(s)",days, hours, minutes, sec_left);  
   dateintmean=dateintsum/k2cpt;    return ascdiff;
    }
   fclose(ficresp);  
   free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);  /***************** f1dim *************************/
   free_vector(pp,1,nlstate);  extern int ncom; 
    extern double *pcom,*xicom;
   /* End of Freq */  extern double (*nrfunc)(double []); 
 }   
   double f1dim(double x) 
 /************ Prevalence ********************/  { 
 void prevalence(int agemin, float agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, double calagedate)    int j; 
 {  /* Some frequencies */    double f;
      double *xt; 
   int i, m, jk, k1, i1, j1, bool, z1,z2,j;   
   double ***freq; /* Frequencies */    xt=vector(1,ncom); 
   double *pp;    for (j=1;j<=ncom;j++) xt[j]=pcom[j]+x*xicom[j]; 
   double pos, k2;    f=(*nrfunc)(xt); 
     free_vector(xt,1,ncom); 
   pp=vector(1,nlstate);    return f; 
   probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);  } 
    
   freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,agemin,agemax+3);  /*****************brent *************************/
   j1=0;  double brent(double ax, double bx, double cx, double (*f)(double), double tol,  double *xmin) 
    {
   j=cptcoveff;    /* Given a function f, and given a bracketing triplet of abscissas ax, bx, cx (such that bx is
   if (cptcovn<1) {j=1;ncodemax[1]=1;}     * between ax and cx, and f(bx) is less than both f(ax) and f(cx) ), this routine isolates
       * the minimum to a fractional precision of about tol using Brent’s method. The abscissa of
   for(k1=1; k1<=j;k1++){     * the minimum is returned as xmin, and the minimum function value is returned as brent , the
     for(i1=1; i1<=ncodemax[k1];i1++){     * returned function value. 
       j1++;    */
          int iter; 
       for (i=-1; i<=nlstate+ndeath; i++)      double a,b,d,etemp;
         for (jk=-1; jk<=nlstate+ndeath; jk++)      double fu=0,fv,fw,fx;
           for(m=agemin; m <= agemax+3; m++)    double ftemp=0.;
             freq[i][jk][m]=0;    double p,q,r,tol1,tol2,u,v,w,x,xm; 
          double e=0.0; 
       for (i=1; i<=imx; i++) {   
         bool=1;    a=(ax < cx ? ax : cx); 
         if  (cptcovn>0) {    b=(ax > cx ? ax : cx); 
           for (z1=1; z1<=cptcoveff; z1++)    x=w=v=bx; 
             if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtab[j1][z1]])    fw=fv=fx=(*f)(x); 
               bool=0;    for (iter=1;iter<=ITMAX;iter++) { 
         }      xm=0.5*(a+b); 
         if (bool==1) {      tol2=2.0*(tol1=tol*fabs(x)+ZEPS); 
           for(m=firstpass; m<=lastpass; m++){      /*          if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret)))*/
             k2=anint[m][i]+(mint[m][i]/12.);      printf(".");fflush(stdout);
             if ((k2>=dateprev1) && (k2<=dateprev2)) {      fprintf(ficlog,".");fflush(ficlog);
               if(agev[m][i]==0) agev[m][i]=agemax+1;  #ifdef DEBUGBRENT
               if(agev[m][i]==1) agev[m][i]=agemax+2;      printf("br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
               if (m<lastpass) {      fprintf(ficlog,"br %d,x=%.10e xm=%.10e b=%.10e a=%.10e tol=%.10e tol1=%.10e tol2=%.10e x-xm=%.10e fx=%.12e fu=%.12e,fw=%.12e,ftemp=%.12e,ftol=%.12e\n",iter,x,xm,b,a,tol,tol1,tol2,(x-xm),fx,fu,fw,ftemp,ftol);
                 if (calagedate>0)      /*          if ((fabs(x-xm) <= (tol2-0.5*(b-a)))||(2.0*fabs(fu-ftemp) <= ftol*1.e-2*(fabs(fu)+fabs(ftemp)))) { */
                   freq[s[m][i]][s[m+1][i]][(int)(agev[m][i]+1-((int)calagedate %12)/12.)] += weight[i];  #endif
                 else      if (fabs(x-xm) <= (tol2-0.5*(b-a))){ 
                   freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];        *xmin=x; 
                 freq[s[m][i]][s[m+1][i]][(int)(agemax+3)] += weight[i];        return fx; 
               }      } 
             }      ftemp=fu;
           }      if (fabs(e) > tol1) { 
         }        r=(x-w)*(fx-fv); 
       }        q=(x-v)*(fx-fw); 
       for(i=(int)agemin; i <= (int)agemax+3; i++){        p=(x-v)*q-(x-w)*r; 
         for(jk=1; jk <=nlstate ; jk++){        q=2.0*(q-r); 
           for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)        if (q > 0.0) p = -p; 
             pp[jk] += freq[jk][m][i];        q=fabs(q); 
         }        etemp=e; 
         for(jk=1; jk <=nlstate ; jk++){        e=d; 
           for(m=-1, pos=0; m <=0 ; m++)        if (fabs(p) >= fabs(0.5*q*etemp) || p <= q*(a-x) || p >= q*(b-x)) 
             pos += freq[jk][m][i];          d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
         }        else { 
                  d=p/q; 
         for(jk=1; jk <=nlstate ; jk++){          u=x+d; 
           for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)          if (u-a < tol2 || b-u < tol2) 
             pp[jk] += freq[jk][m][i];            d=SIGN(tol1,xm-x); 
         }        } 
              } else { 
         for(jk=1,pos=0; jk <=nlstate ; jk++) pos += pp[jk];        d=CGOLD*(e=(x >= xm ? a-x : b-x)); 
              } 
         for(jk=1; jk <=nlstate ; jk++){          u=(fabs(d) >= tol1 ? x+d : x+SIGN(tol1,d)); 
           if( i <= (int) agemax){      fu=(*f)(u); 
             if(pos>=1.e-5){      if (fu <= fx) { 
               probs[i][jk][j1]= pp[jk]/pos;        if (u >= x) a=x; else b=x; 
             }        SHFT(v,w,x,u) 
           }        SHFT(fv,fw,fx,fu) 
         }/* end jk */      } else { 
       }/* end i */        if (u < x) a=u; else b=u; 
     } /* end i1 */        if (fu <= fw || w == x) { 
   } /* end k1 */          v=w; 
           w=u; 
            fv=fw; 
   free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath,(int) agemin,(int) agemax+3);          fw=fu; 
   free_vector(pp,1,nlstate);        } else if (fu <= fv || v == x || v == w) { 
            v=u; 
 }  /* End of Freq */          fv=fu; 
         } 
 /************* Waves Concatenation ***************/      } 
     } 
 void  concatwav(int wav[], int **dh, int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)    nrerror("Too many iterations in brent"); 
 {    *xmin=x; 
   /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.    return fx; 
      Death is a valid wave (if date is known).  } 
      mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i  
      dh[m][i] of dh[mw[mi][i][i] is the delay between two effective waves m=mw[mi][i]  /****************** mnbrak ***********************/
      and mw[mi+1][i]. dh depends on stepm.  
      */  void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, double *fc, 
               double (*func)(double)) 
   int i, mi, m;  { /* Given a function func , and given distinct initial points ax and bx , this routine searches in
   /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;  the downhill direction (defined by the function as evaluated at the initial points) and returns
      double sum=0., jmean=0.;*/  new points ax , bx , cx that bracket a minimum of the function. Also returned are the function
   int first;  values at the three points, fa, fb , and fc such that fa > fb and fb < fc.
   int j, k=0,jk, ju, jl;     */
   double sum=0.;    double ulim,u,r,q, dum;
   first=0;    double fu; 
   jmin=1e+5;  
   jmax=-1;    double scale=10.;
   jmean=0.;    int iterscale=0;
   for(i=1; i<=imx; i++){  
     mi=0;    *fa=(*func)(*ax); /*  xta[j]=pcom[j]+(*ax)*xicom[j]; fa=f(xta[j])*/
     m=firstpass;    *fb=(*func)(*bx); /*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) */
     while(s[m][i] <= nlstate){  
       if(s[m][i]>=1)  
         mw[++mi][i]=m;    /* while(*fb != *fb){ /\* *ax should be ok, reducing distance to *ax *\/ */
       if(m >=lastpass)    /*   printf("Warning mnbrak *fb = %lf, *bx=%lf *ax=%lf *fa==%lf iter=%d\n",*fb, *bx, *ax, *fa, iterscale++); */
         break;    /*   *bx = *ax - (*ax - *bx)/scale; */
       else    /*   *fb=(*func)(*bx);  /\*  xtb[j]=pcom[j]+(*bx)*xicom[j]; fb=f(xtb[j]) *\/ */
         m++;    /* } */
     }/* end while */  
     if (s[m][i] > nlstate){    if (*fb > *fa) { 
       mi++;     /* Death is another wave */      SHFT(dum,*ax,*bx,dum) 
       /* if(mi==0)  never been interviewed correctly before death */      SHFT(dum,*fb,*fa,dum) 
          /* Only death is a correct wave */    } 
       mw[mi][i]=m;    *cx=(*bx)+GOLD*(*bx-*ax); 
     }    *fc=(*func)(*cx); 
   #ifdef DEBUG
     wav[i]=mi;    printf("mnbrak0 *fb=%.12e *fc=%.12e\n",*fb,*fc);
     if(mi==0){    fprintf(ficlog,"mnbrak0 *fb=%.12e *fc=%.12e\n",*fb,*fc);
       if(first==0){  #endif
         printf("Warning, no any valid information for:%d line=%d and may be others, see log file\n",num[i],i);    while (*fb > *fc) { /* Declining a,b,c with fa> fb > fc */
         first=1;      r=(*bx-*ax)*(*fb-*fc); 
       }      q=(*bx-*cx)*(*fb-*fa); 
       if(first==1){      u=(*bx)-((*bx-*cx)*q-(*bx-*ax)*r)/ 
         fprintf(ficlog,"Warning, no any valid information for:%d line=%d\n",num[i],i);        (2.0*SIGN(FMAX(fabs(q-r),TINY),q-r)); /* Minimum abscissa of a parabolic estimated from (a,fa), (b,fb) and (c,fc). */
       }      ulim=(*bx)+GLIMIT*(*cx-*bx); /* Maximum abscissa where function should be evaluated */
     } /* end mi==0 */      if ((*bx-u)*(u-*cx) > 0.0) { /* if u_p is between b and c */
   }        fu=(*func)(u); 
   #ifdef DEBUG
   for(i=1; i<=imx; i++){        /* f(x)=A(x-u)**2+f(u) */
     for(mi=1; mi<wav[i];mi++){        double A, fparabu; 
       if (stepm <=0)        A= (*fb - *fa)/(*bx-*ax)/(*bx+*ax-2*u);
         dh[mi][i]=1;        fparabu= *fa - A*(*ax-u)*(*ax-u);
       else{        printf("mnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu);
         if (s[mw[mi+1][i]][i] > nlstate) {        fprintf(ficlog, "mnbrak (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf, fparabu=%.12f)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu, fparabu);
           if (agedc[i] < 2*AGESUP) {        /* And thus,it can be that fu > *fc even if fparabu < *fc */
           j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12);        /* mnbrak (*ax=7.666299858533, *fa=299039.693133272231), (*bx=8.595447774979, *fb=298976.598289369489),
           if(j==0) j=1;  /* Survives at least one month after exam */          (*cx=10.098840694817, *fc=298946.631474258087),  (*u=9.852501168332, fu=298948.773013752128, fparabu=298945.434711494134) */
           k=k+1;        /* In that case, there is no bracket in the output! Routine is wrong with many consequences.*/
           if (j >= jmax) jmax=j;  #endif 
           if (j <= jmin) jmin=j;  #ifdef MNBRAKORIGINAL
           sum=sum+j;  #else
           /*if (j<0) printf("j=%d num=%d \n",j,i); */  /*       if (fu > *fc) { */
           }  /* #ifdef DEBUG */
         }  /*       printf("mnbrak4  fu > fc \n"); */
         else{  /*       fprintf(ficlog, "mnbrak4 fu > fc\n"); */
           j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));  /* #endif */
           k=k+1;  /*      /\* SHFT(u,*cx,*cx,u) /\\* ie a=c, c=u and u=c; in that case, next SHFT(a,b,c,u) will give a=b=b, b=c=u, c=u=c and *\\/  *\/ */
           if (j >= jmax) jmax=j;  /*      /\* SHFT(*fa,*fc,fu,*fc) /\\* (b, u, c) is a bracket while test fb > fc will be fu > fc  will exit *\\/ *\/ */
           else if (j <= jmin)jmin=j;  /*      dum=u; /\* Shifting c and u *\/ */
           /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */  /*      u = *cx; */
           sum=sum+j;  /*      *cx = dum; */
         }  /*      dum = fu; */
         jk= j/stepm;  /*      fu = *fc; */
         jl= j -jk*stepm;  /*      *fc =dum; */
         ju= j -(jk+1)*stepm;  /*       } else { /\* end *\/ */
         if(jl <= -ju)  /* #ifdef DEBUG */
           dh[mi][i]=jk;  /*       printf("mnbrak3  fu < fc \n"); */
         else  /*       fprintf(ficlog, "mnbrak3 fu < fc\n"); */
           dh[mi][i]=jk+1;  /* #endif */
         if(dh[mi][i]==0)  /*      dum=u; /\* Shifting c and u *\/ */
           dh[mi][i]=1; /* At least one step */  /*      u = *cx; */
       }  /*      *cx = dum; */
     }  /*      dum = fu; */
   }  /*      fu = *fc; */
   jmean=sum/k;  /*      *fc =dum; */
   printf("Delay (in months) between two waves Min=%d Max=%d Mean=%f\n\n ",jmin, jmax,jmean);  /*       } */
   fprintf(ficlog,"Delay (in months) between two waves Min=%d Max=%d Mean=%f\n\n ",jmin, jmax,jmean);  #ifdef DEBUG
  }        printf("mnbrak34  fu < or >= fc \n");
         fprintf(ficlog, "mnbrak34 fu < fc\n");
 /*********** Tricode ****************************/  #endif
 void tricode(int *Tvar, int **nbcode, int imx)        dum=u; /* Shifting c and u */
 {        u = *cx;
   int Ndum[20],ij=1, k, j, i;        *cx = dum;
   int cptcode=0;        dum = fu;
   cptcoveff=0;        fu = *fc;
          *fc =dum;
   for (k=0; k<19; k++) Ndum[k]=0;  #endif
   for (k=1; k<=7; k++) ncodemax[k]=0;      } else if ((*cx-u)*(u-ulim) > 0.0) { /* u is after c but before ulim */
   #ifdef DEBUG
   for (j=1; j<=(cptcovn+2*cptcovprod); j++) {        printf("mnbrak2  u after c but before ulim\n");
     for (i=1; i<=imx; i++) {        fprintf(ficlog, "mnbrak2 u after c but before ulim\n");
       ij=(int)(covar[Tvar[j]][i]);  #endif
       Ndum[ij]++;        fu=(*func)(u); 
       /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/        if (fu < *fc) { 
       if (ij > cptcode) cptcode=ij;  #ifdef DEBUG
     }        printf("mnbrak2  u after c but before ulim AND fu < fc\n");
         fprintf(ficlog, "mnbrak2 u after c but before ulim AND fu <fc \n");
     for (i=0; i<=cptcode; i++) {  #endif
       if(Ndum[i]!=0) ncodemax[j]++;          SHFT(*bx,*cx,u,*cx+GOLD*(*cx-*bx)) 
     }          SHFT(*fb,*fc,fu,(*func)(u)) 
     ij=1;        } 
       } else if ((u-ulim)*(ulim-*cx) >= 0.0) { /* u outside ulim (verifying that ulim is beyond c) */
   #ifdef DEBUG
     for (i=1; i<=ncodemax[j]; i++) {        printf("mnbrak2  u outside ulim (verifying that ulim is beyond c)\n");
       for (k=0; k<=19; k++) {        fprintf(ficlog, "mnbrak2 u outside ulim (verifying that ulim is beyond c)\n");
         if (Ndum[k] != 0) {  #endif
           nbcode[Tvar[j]][ij]=k;        u=ulim; 
                  fu=(*func)(u); 
           ij++;      } else { /* u could be left to b (if r > q parabola has a maximum) */
         }  #ifdef DEBUG
         if (ij > ncodemax[j]) break;        printf("mnbrak2  u could be left to b (if r > q parabola has a maximum)\n");
       }          fprintf(ficlog, "mnbrak2  u could be left to b (if r > q parabola has a maximum)\n");
     }  #endif
   }          u=(*cx)+GOLD*(*cx-*bx); 
         fu=(*func)(u); 
  for (k=0; k<19; k++) Ndum[k]=0;      } /* end tests */
       SHFT(*ax,*bx,*cx,u) 
  for (i=1; i<=ncovmodel-2; i++) {      SHFT(*fa,*fb,*fc,fu) 
    ij=Tvar[i];  #ifdef DEBUG
    Ndum[ij]++;        printf("mnbrak2 (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu);
  }        fprintf(ficlog, "mnbrak2 (*ax=%.12f, *fa=%.12lf), (*bx=%.12f, *fb=%.12lf), (*cx=%.12f, *fc=%.12lf),  (*u=%.12f, fu=%.12lf)\n",*ax,*fa,*bx,*fb,*cx,*fc,u,fu);
   #endif
  ij=1;    } /* end while; ie return (a, b, c, fa, fb, fc) such that a < b < c with f(a) > f(b) and fb < f(c) */
  for (i=1; i<=10; i++) {  } 
    if((Ndum[i]!=0) && (i<=ncovcol)){  
      Tvaraff[ij]=i;  /*************** linmin ************************/
      ij++;  /* Given an n -dimensional point p[1..n] and an n -dimensional direction xi[1..n] , moves and
    }  resets p to where the function func(p) takes on a minimum along the direction xi from p ,
  }  and replaces xi by the actual vector displacement that p was moved. Also returns as fret
    the value of func at the returned location p . This is actually all accomplished by calling the
  cptcoveff=ij-1;  routines mnbrak and brent .*/
 }  int ncom; 
   double *pcom,*xicom;
 /*********** Health Expectancies ****************/  double (*nrfunc)(double []); 
    
 void evsij(char fileres[], double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int ij, int estepm,double delti[],double **matcov )  void linmin(double p[], double xi[], int n, double *fret,double (*func)(double [])) 
   { 
 {    double brent(double ax, double bx, double cx, 
   /* Health expectancies */                 double (*f)(double), double tol, double *xmin); 
   int i, j, nhstepm, hstepm, h, nstepm, k, cptj;    double f1dim(double x); 
   double age, agelim, hf;    void mnbrak(double *ax, double *bx, double *cx, double *fa, double *fb, 
   double ***p3mat,***varhe;                double *fc, double (*func)(double)); 
   double **dnewm,**doldm;    int j; 
   double *xp;    double xx,xmin,bx,ax; 
   double **gp, **gm;    double fx,fb,fa;
   double ***gradg, ***trgradg;  
   int theta;  #ifdef LINMINORIGINAL
   #else
   varhe=ma3x(1,nlstate*2,1,nlstate*2,(int) bage, (int) fage);    double scale=10., axs, xxs; /* Scale added for infinity */
   xp=vector(1,npar);  #endif
   dnewm=matrix(1,nlstate*2,1,npar);    
   doldm=matrix(1,nlstate*2,1,nlstate*2);    ncom=n; 
      pcom=vector(1,n); 
   fprintf(ficreseij,"# Health expectancies\n");    xicom=vector(1,n); 
   fprintf(ficreseij,"# Age");    nrfunc=func; 
   for(i=1; i<=nlstate;i++)    for (j=1;j<=n;j++) { 
     for(j=1; j<=nlstate;j++)      pcom[j]=p[j]; 
       fprintf(ficreseij," %1d-%1d (SE)",i,j);      xicom[j]=xi[j]; /* Former scale xi[j] of currrent direction i */
   fprintf(ficreseij,"\n");    } 
   
   if(estepm < stepm){  #ifdef LINMINORIGINAL
     printf ("Problem %d lower than %d\n",estepm, stepm);    xx=1.;
   }  #else
   else  hstepm=estepm;      axs=0.0;
   /* We compute the life expectancy from trapezoids spaced every estepm months    xxs=1.;
    * This is mainly to measure the difference between two models: for example    do{
    * if stepm=24 months pijx are given only every 2 years and by summing them      xx= xxs;
    * we are calculating an estimate of the Life Expectancy assuming a linear  #endif
    * progression inbetween and thus overestimating or underestimating according      ax=0.;
    * to the curvature of the survival function. If, for the same date, we      mnbrak(&ax,&xx,&bx,&fa,&fx,&fb,f1dim);  /* Outputs: xtx[j]=pcom[j]+(*xx)*xicom[j]; fx=f(xtx[j]) */
    * estimate the model with stepm=1 month, we can keep estepm to 24 months      /* brackets with inputs ax=0 and xx=1, but points, pcom=p, and directions values, xicom=xi, are sent via f1dim(x) */
    * to compare the new estimate of Life expectancy with the same linear      /* xt[x,j]=pcom[j]+x*xicom[j]  f(ax) = f(xt(a,j=1,n)) = f(p(j) + 0 * xi(j)) and  f(xx) = f(xt(x, j=1,n)) = f(p(j) + 1 * xi(j))   */
    * hypothesis. A more precise result, taking into account a more precise      /* Outputs: fa=f(p(j)) and fx=f(p(j) + xxs * xi(j) ) and f(bx)= f(p(j)+ bx* xi(j)) */
    * curvature will be obtained if estepm is as small as stepm. */      /* Given input ax=axs and xx=xxs, xx might be too far from ax to get a finite f(xx) */
       /* Searches on line, outputs (ax, xx, bx) such that fx < min(fa and fb) */
   /* For example we decided to compute the life expectancy with the smallest unit */      /* Find a bracket a,x,b in direction n=xi ie xicom, order may change. Scale is [0:xxs*xi[j]] et non plus  [0:xi[j]]*/
   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm.  #ifdef LINMINORIGINAL
      nhstepm is the number of hstepm from age to agelim  #else
      nstepm is the number of stepm from age to agelin.      if (fx != fx){
      Look at hpijx to understand the reason of that which relies in memory size          xxs=xxs/scale; /* Trying a smaller xx, closer to initial ax=0 */
      and note for a fixed period like estepm months */          printf("|");
   /* We decided (b) to get a life expectancy respecting the most precise curvature of the          fprintf(ficlog,"|");
      survival function given by stepm (the optimization length). Unfortunately it  #ifdef DEBUGLINMIN
      means that if the survival funtion is printed only each two years of age and if          printf("\nLinmin NAN : input [axs=%lf:xxs=%lf], mnbrak outputs fx=%lf <(fb=%lf and fa=%lf) with xx=%lf in [ax=%lf:bx=%lf] \n",  axs, xxs, fx,fb, fa, xx, ax, bx);
      you sum them up and add 1 year (area under the trapezoids) you won't get the same  #endif
      results. So we changed our mind and took the option of the best precision.      }
   */    }while(fx != fx);
   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */  #endif
     
   agelim=AGESUP;  #ifdef DEBUGLINMIN
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */    printf("\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
     /* nhstepm age range expressed in number of stepm */    fprintf(ficlog,"\nLinmin after mnbrak: ax=%12.7f xx=%12.7f bx=%12.7f fa=%12.2f fx=%12.2f fb=%12.2f\n",  ax,xx,bx,fa,fx,fb);
     nstepm=(int) rint((agelim-age)*YEARM/stepm);  #endif
     /* Typically if 20 years nstepm = 20*12/6=40 stepm */    *fret=brent(ax,xx,bx,f1dim,TOL,&xmin); /* Giving a bracketting triplet (ax, xx, bx), find a minimum, xmin, according to f1dim, *fret(xmin),*/
     /* if (stepm >= YEARM) hstepm=1;*/    /* fa = f(p[j] + ax * xi[j]), fx = f(p[j] + xx * xi[j]), fb = f(p[j] + bx * xi[j]) */
     nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */    /* fmin = f(p[j] + xmin * xi[j]) */
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    /* P+lambda n in that direction (lambdamin), with TOL between abscisses */
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate*2);    /* f1dim(xmin): for (j=1;j<=ncom;j++) xt[j]=pcom[j]+xmin*xicom[j]; */
     gp=matrix(0,nhstepm,1,nlstate*2);  #ifdef DEBUG
     gm=matrix(0,nhstepm,1,nlstate*2);    printf("retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);
     fprintf(ficlog,"retour brent fret=%.12e xmin=%.12e\n",*fret,xmin);
     /* Computed by stepm unit matrices, product of hstepm matrices, stored  #endif
        in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */  #ifdef DEBUGLINMIN
     hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, ij);      printf("linmin end ");
      fprintf(ficlog,"linmin end ");
   #endif
     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */    for (j=1;j<=n;j++) { 
   #ifdef LINMINORIGINAL
     /* Computing Variances of health expectancies */      xi[j] *= xmin; 
   #else
      for(theta=1; theta <=npar; theta++){  #ifdef DEBUGLINMIN
       for(i=1; i<=npar; i++){      if(xxs <1.0)
         xp[i] = x[i] + (i==theta ?delti[theta]:0);        printf(" before xi[%d]=%12.8f", j,xi[j]);
       }  #endif
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);        xi[j] *= xmin*xxs; /* xi rescaled by xmin and number of loops: if xmin=-1.237 and xi=(1,0,...,0) xi=(-1.237,0,...,0) */
    #ifdef DEBUGLINMIN
       cptj=0;      if(xxs <1.0)
       for(j=1; j<= nlstate; j++){        printf(" after xi[%d]=%12.8f, xmin=%12.8f, ax=%12.8f, xx=%12.8f, bx=%12.8f, xxs=%12.8f", j,xi[j], xmin, ax, xx, bx,xxs );
         for(i=1; i<=nlstate; i++){  #endif
           cptj=cptj+1;  #endif
           for(h=0, gp[h][cptj]=0.; h<=nhstepm-1; h++){      p[j] += xi[j]; /* Parameters values are updated accordingly */
             gp[h][cptj] = (p3mat[i][j][h]+p3mat[i][j][h+1])/2.;    } 
           }  #ifdef DEBUGLINMIN
         }    printf("\n");
       }    printf("Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
          fprintf(ficlog,"Comparing last *frec(xmin=%12.8f)=%12.8f from Brent and frec(0.)=%12.8f \n", xmin, *fret, (*func)(p));
          for (j=1;j<=n;j++) { 
       for(i=1; i<=npar; i++)      printf(" xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
         xp[i] = x[i] - (i==theta ?delti[theta]:0);      fprintf(ficlog," xi[%d]= %14.10f p[%d]= %12.7f",j,xi[j],j,p[j]);
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);        if(j % ncovmodel == 0){
              printf("\n");
       cptj=0;        fprintf(ficlog,"\n");
       for(j=1; j<= nlstate; j++){      }
         for(i=1;i<=nlstate;i++){    }
           cptj=cptj+1;  #else
           for(h=0, gm[h][cptj]=0.; h<=nhstepm-1; h++){  #endif
             gm[h][cptj] = (p3mat[i][j][h]+p3mat[i][j][h+1])/2.;    free_vector(xicom,1,n); 
           }    free_vector(pcom,1,n); 
         }  } 
       }  
       for(j=1; j<= nlstate*2; j++)  
         for(h=0; h<=nhstepm-1; h++){  /*************** powell ************************/
           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];  /*
         }  Minimization of a function func of n variables. Input consists of an initial starting point
      }  p[1..n] ; an initial matrix xi[1..n][1..n] , whose columns contain the initial set of di-
      rections (usually the n unit vectors); and ftol , the fractional tolerance in the function value
 /* End theta */  such that failure to decrease by more than this amount on one iteration signals doneness. On
   output, p is set to the best point found, xi is the then-current direction set, fret is the returned
      trgradg =ma3x(0,nhstepm,1,nlstate*2,1,npar);  function value at p , and iter is the number of iterations taken. The routine linmin is used.
    */
      for(h=0; h<=nhstepm-1; h++)  void powell(double p[], double **xi, int n, double ftol, int *iter, double *fret, 
       for(j=1; j<=nlstate*2;j++)              double (*func)(double [])) 
         for(theta=1; theta <=npar; theta++)  { 
           trgradg[h][j][theta]=gradg[h][theta][j];    void linmin(double p[], double xi[], int n, double *fret, 
                      double (*func)(double [])); 
     int i,ibig,j; 
      for(i=1;i<=nlstate*2;i++)    double del,t,*pt,*ptt,*xit;
       for(j=1;j<=nlstate*2;j++)    double directest;
         varhe[i][j][(int)age] =0.;    double fp,fptt;
     double *xits;
      printf("%d|",(int)age);fflush(stdout);    int niterf, itmp;
      fprintf(ficlog,"%d|",(int)age);fflush(ficlog);  
      for(h=0;h<=nhstepm-1;h++){    pt=vector(1,n); 
       for(k=0;k<=nhstepm-1;k++){    ptt=vector(1,n); 
         matprod2(dnewm,trgradg[h],1,nlstate*2,1,npar,1,npar,matcov);    xit=vector(1,n); 
         matprod2(doldm,dnewm,1,nlstate*2,1,npar,1,nlstate*2,gradg[k]);    xits=vector(1,n); 
         for(i=1;i<=nlstate*2;i++)    *fret=(*func)(p); 
           for(j=1;j<=nlstate*2;j++)    for (j=1;j<=n;j++) pt[j]=p[j]; 
             varhe[i][j][(int)age] += doldm[i][j]*hf*hf;    rcurr_time = time(NULL);  
       }    for (*iter=1;;++(*iter)) { 
     }      fp=(*fret); /* From former iteration or initial value */
     /* Computing expectancies */      ibig=0; 
     for(i=1; i<=nlstate;i++)      del=0.0; 
       for(j=1; j<=nlstate;j++)      rlast_time=rcurr_time;
         for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){      /* (void) gettimeofday(&curr_time,&tzp); */
           eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;      rcurr_time = time(NULL);  
                curr_time = *localtime(&rcurr_time);
 /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/      printf("\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret, rcurr_time-rlast_time, rcurr_time-rstart_time);fflush(stdout);
       fprintf(ficlog,"\nPowell iter=%d -2*LL=%.12f %ld sec. %ld sec.",*iter,*fret,rcurr_time-rlast_time, rcurr_time-rstart_time); fflush(ficlog);
         }  /*     fprintf(ficrespow,"%d %.12f %ld",*iter,*fret,curr_time.tm_sec-start_time.tm_sec); */
       for (i=1;i<=n;i++) {
     fprintf(ficreseij,"%3.0f",age );        printf(" %d %.12f",i, p[i]);
     cptj=0;        fprintf(ficlog," %d %.12lf",i, p[i]);
     for(i=1; i<=nlstate;i++)        fprintf(ficrespow," %.12lf", p[i]);
       for(j=1; j<=nlstate;j++){      }
         cptj++;      printf("\n");
         fprintf(ficreseij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[cptj][cptj][(int)age]) );      fprintf(ficlog,"\n");
       }      fprintf(ficrespow,"\n");fflush(ficrespow);
     fprintf(ficreseij,"\n");      if(*iter <=3){
            tml = *localtime(&rcurr_time);
     free_matrix(gm,0,nhstepm,1,nlstate*2);        strcpy(strcurr,asctime(&tml));
     free_matrix(gp,0,nhstepm,1,nlstate*2);        rforecast_time=rcurr_time; 
     free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*2);        itmp = strlen(strcurr);
     free_ma3x(trgradg,0,nhstepm,1,nlstate*2,1,npar);        if(strcurr[itmp-1]=='\n')  /* Windows outputs with a new line */
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);          strcurr[itmp-1]='\0';
   }        printf("\nConsidering the time needed for the last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
   printf("\n");        fprintf(ficlog,"\nConsidering the time needed for this last iteration #%d: %ld seconds,\n",*iter,rcurr_time-rlast_time);
   fprintf(ficlog,"\n");        for(niterf=10;niterf<=30;niterf+=10){
           rforecast_time=rcurr_time+(niterf-*iter)*(rcurr_time-rlast_time);
   free_vector(xp,1,npar);          forecast_time = *localtime(&rforecast_time);
   free_matrix(dnewm,1,nlstate*2,1,npar);          strcpy(strfor,asctime(&forecast_time));
   free_matrix(doldm,1,nlstate*2,1,nlstate*2);          itmp = strlen(strfor);
   free_ma3x(varhe,1,nlstate*2,1,nlstate*2,(int) bage, (int)fage);          if(strfor[itmp-1]=='\n')
 }          strfor[itmp-1]='\0';
           printf("   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
 /************ Variance ******************/          fprintf(ficlog,"   - if your program needs %d iterations to converge, convergence will be \n   reached in %s i.e.\n   on %s (current time is %s);\n",niterf, asc_diff_time(rforecast_time-rcurr_time,tmpout),strfor,strcurr);
 void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij, int estepm, int cptcov, int cptcod, int popbased)        }
 {      }
   /* Variance of health expectancies */      for (i=1;i<=n;i++) { /* For each direction i */
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/        for (j=1;j<=n;j++) xit[j]=xi[j][i]; /* Directions stored from previous iteration with previous scales */
   /* double **newm;*/        fptt=(*fret); 
   double **dnewm,**doldm;  #ifdef DEBUG
   double **dnewmp,**doldmp;        printf("fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
   int i, j, nhstepm, hstepm, h, nstepm ;        fprintf(ficlog, "fret=%lf, %lf, %lf \n", *fret, *fret, *fret);
   int k, cptcode;  #endif
   double *xp;        printf("%d",i);fflush(stdout); /* print direction (parameter) i */
   double **gp, **gm;  /* for var eij */        fprintf(ficlog,"%d",i);fflush(ficlog);
   double ***gradg, ***trgradg; /*for var eij */        linmin(p,xit,n,fret,func); /* Point p[n]. xit[n] has been loaded for direction i as input.*/
   double **gradgp, **trgradgp; /* for var p point j */                                      /* Outputs are fret(new point p) p is updated and xit rescaled */
   double *gpp, *gmp; /* for var p point j */        if (fabs(fptt-(*fret)) > del) { /* We are keeping the max gain on each of the n directions */
   double **varppt; /* for var p point j nlstate to nlstate+ndeath */          /* because that direction will be replaced unless the gain del is small */
   double ***p3mat;          /* in comparison with the 'probable' gain, mu^2, with the last average direction. */
   double age,agelim, hf;          /* Unless the n directions are conjugate some gain in the determinant may be obtained */
   int theta;          /* with the new direction. */
   char digit[4];          del=fabs(fptt-(*fret)); 
   char digitp[16];          ibig=i; 
         } 
   char fileresprobmorprev[FILENAMELENGTH];  #ifdef DEBUG
         printf("%d %.12e",i,(*fret));
   if(popbased==1)        fprintf(ficlog,"%d %.12e",i,(*fret));
     strcpy(digitp,"-populbased-");        for (j=1;j<=n;j++) {
   else          xits[j]=FMAX(fabs(p[j]-pt[j]),1.e-5);
     strcpy(digitp,"-stablbased-");          printf(" x(%d)=%.12e",j,xit[j]);
           fprintf(ficlog," x(%d)=%.12e",j,xit[j]);
   strcpy(fileresprobmorprev,"prmorprev");        }
   sprintf(digit,"%-d",ij);        for(j=1;j<=n;j++) {
   /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/          printf(" p(%d)=%.12e",j,p[j]);
   strcat(fileresprobmorprev,digit); /* Tvar to be done */          fprintf(ficlog," p(%d)=%.12e",j,p[j]);
   strcat(fileresprobmorprev,digitp); /* Popbased or not */        }
   strcat(fileresprobmorprev,fileres);        printf("\n");
   if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {        fprintf(ficlog,"\n");
     printf("Problem with resultfile: %s\n", fileresprobmorprev);  #endif
     fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);      } /* end loop on each direction i */
   }      /* Convergence test will use last linmin estimation (fret) and compare former iteration (fp) */ 
   printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);      /* But p and xit have been updated at the end of linmin, *fret corresponds to new p, xit  */
   fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);      /* New value of last point Pn is not computed, P(n-1) */
   fprintf(ficresprobmorprev,"# probabilities of dying during a year and weighted mean w1*p1j+w2*p2j+... stand dev in()\n");      if (2.0*fabs(fp-(*fret)) <= ftol*(fabs(fp)+fabs(*fret))) { /* Did we reach enough precision? */
   fprintf(ficresprobmorprev,"# Age cov=%-d",ij);        /* We could compare with a chi^2. chisquare(0.95,ddl=1)=3.84 */
   for(j=nlstate+1; j<=(nlstate+ndeath);j++){        /* By adding age*age in a model, the new -2LL should be lower and the difference follows a */
     fprintf(ficresprobmorprev," p.%-d SE",j);        /* a chisquare statistics with 1 degree. To be significant at the 95% level, it should have */
     for(i=1; i<=nlstate;i++)        /* decreased of more than 3.84  */
       fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);        /* By adding age*age and V1*age the gain (-2LL) should be more than 5.99 (ddl=2) */
   }          /* By using V1+V2+V3, the gain should be  7.82, compared with basic 1+age. */
   fprintf(ficresprobmorprev,"\n");        /* By adding 10 parameters more the gain should be 18.31 */
   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) {  
     printf("Problem with gnuplot file: %s\n", optionfilegnuplot);        /* Starting the program with initial values given by a former maximization will simply change */
     fprintf(ficlog,"Problem with gnuplot file: %s\n", optionfilegnuplot);        /* the scales of the directions and the directions, because the are reset to canonical directions */
     exit(0);        /* Thus the first calls to linmin will give new points and better maximizations until fp-(*fret) is */
   }        /* under the tolerance value. If the tolerance is very small 1.e-9, it could last long.  */
   else{  #ifdef DEBUG
     fprintf(ficgp,"\n# Routine varevsij");        int k[2],l;
   }        k[0]=1;
   if((fichtm=fopen(optionfilehtm,"a"))==NULL) {        k[1]=-1;
     printf("Problem with html file: %s\n", optionfilehtm);        printf("Max: %.12e",(*func)(p));
     fprintf(ficlog,"Problem with html file: %s\n", optionfilehtm);        fprintf(ficlog,"Max: %.12e",(*func)(p));
     exit(0);        for (j=1;j<=n;j++) {
   }          printf(" %.12e",p[j]);
   else{          fprintf(ficlog," %.12e",p[j]);
     fprintf(fichtm,"\n<li><h4> Computing step probabilities of dying and weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");        }
   }        printf("\n");
   varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);        fprintf(ficlog,"\n");
         for(l=0;l<=1;l++) {
   fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are the stable prevalence in health states i\n");          for (j=1;j<=n;j++) {
   fprintf(ficresvij,"# Age");            ptt[j]=p[j]+(p[j]-pt[j])*k[l];
   for(i=1; i<=nlstate;i++)            printf("l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
     for(j=1; j<=nlstate;j++)            fprintf(ficlog,"l=%d j=%d ptt=%.12e, xits=%.12e, p=%.12e, xit=%.12e", l,j,ptt[j],xits[j],p[j],xit[j]);
       fprintf(ficresvij," Cov(e%1d, e%1d)",i,j);          }
   fprintf(ficresvij,"\n");          printf("func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
           fprintf(ficlog,"func(ptt)=%.12e, deriv=%.12e\n",(*func)(ptt),(ptt[j]-p[j])/((*func)(ptt)-(*func)(p)));
   xp=vector(1,npar);        }
   dnewm=matrix(1,nlstate,1,npar);  #endif
   doldm=matrix(1,nlstate,1,nlstate);  
   dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);  
   doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);        free_vector(xit,1,n); 
         free_vector(xits,1,n); 
   gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);        free_vector(ptt,1,n); 
   gpp=vector(nlstate+1,nlstate+ndeath);        free_vector(pt,1,n); 
   gmp=vector(nlstate+1,nlstate+ndeath);        return; 
   trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/      } /* enough precision */ 
        if (*iter == ITMAX) nrerror("powell exceeding maximum iterations."); 
   if(estepm < stepm){      for (j=1;j<=n;j++) { /* Computes the extrapolated point P_0 + 2 (P_n-P_0) */
     printf ("Problem %d lower than %d\n",estepm, stepm);        ptt[j]=2.0*p[j]-pt[j]; 
   }        xit[j]=p[j]-pt[j]; 
   else  hstepm=estepm;          pt[j]=p[j]; 
   /* For example we decided to compute the life expectancy with the smallest unit */      } 
   /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm.      fptt=(*func)(ptt); /* f_3 */
      nhstepm is the number of hstepm from age to agelim  #ifdef POWELLF1F3
      nstepm is the number of stepm from age to agelin.  #else
      Look at hpijx to understand the reason of that which relies in memory size      if (fptt < fp) { /* If extrapolated point is better, decide if we keep that new direction or not */
      and note for a fixed period like k years */  #endif
   /* We decided (b) to get a life expectancy respecting the most precise curvature of the        /* (x1 f1=fp), (x2 f2=*fret), (x3 f3=fptt), (xm fm) */
      survival function given by stepm (the optimization length). Unfortunately it        /* From x1 (P0) distance of x2 is at h and x3 is 2h */
      means that if the survival funtion is printed only each two years of age and if        /* Let f"(x2) be the 2nd derivative equal everywhere.  */
      you sum them up and add 1 year (area under the trapezoids) you won't get the same        /* Then the parabolic through (x1,f1), (x2,f2) and (x3,f3) */
      results. So we changed our mind and took the option of the best precision.        /* will reach at f3 = fm + h^2/2 f"m  ; f" = (f1 -2f2 +f3 ) / h**2 */
   */        /* Conditional for using this new direction is that mu^2 = (f1-2f2+f3)^2 /2 < del */
   hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */        /* t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)-del*SQR(fp-fptt); */
   agelim = AGESUP;  #ifdef NRCORIGINAL
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */        t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del)- del*SQR(fp-fptt); /* Original Numerical Recipes in C*/
     nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */  #else
     nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */        t=2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del); /* Intel compiler doesn't work on one line; bug reported */
     p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);        t= t- del*SQR(fp-fptt);
     gradg=ma3x(0,nhstepm,1,npar,1,nlstate);  #endif
     gp=matrix(0,nhstepm,1,nlstate);        directest = fp-2.0*(*fret)+fptt - 2.0 * del; /* If delta was big enough we change it for a new direction */
     gm=matrix(0,nhstepm,1,nlstate);  #ifdef DEBUG
         printf("t1= %.12lf, t2= %.12lf, t=%.12lf  directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
         fprintf(ficlog,"t1= %.12lf, t2= %.12lf, t=%.12lf directest=%.12lf\n", 2.0*(fp-2.0*(*fret)+fptt)*SQR(fp-(*fret)-del),del*SQR(fp-fptt),t,directest);
     for(theta=1; theta <=npar; theta++){        printf("t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
       for(i=1; i<=npar; i++){ /* Computes gradient */               (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
         xp[i] = x[i] + (i==theta ?delti[theta]:0);        fprintf(ficlog,"t3= %.12lf, t4= %.12lf, t3*= %.12lf, t4*= %.12lf\n",SQR(fp-(*fret)-del),SQR(fp-fptt),
       }               (fp-(*fret)-del)*(fp-(*fret)-del),(fp-fptt)*(fp-fptt));
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);          printf("tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);        fprintf(ficlog, "tt= %.12lf, t=%.12lf\n",2.0*(fp-2.0*(*fret)+fptt)*(fp-(*fret)-del)*(fp-(*fret)-del)-del*(fp-fptt)*(fp-fptt),t);
   #endif
       if (popbased==1) {  #ifdef POWELLORIGINAL
         for(i=1; i<=nlstate;i++)        if (t < 0.0) { /* Then we use it for new direction */
           prlim[i][i]=probs[(int)age][i][ij];  #else
       }        if (directest*t < 0.0) { /* Contradiction between both tests */
            printf("directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt,del);
       for(j=1; j<= nlstate; j++){          printf("f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
         for(h=0; h<=nhstepm; h++){          fprintf(ficlog,"directest= %.12lf (if <0 we include P0 Pn as new direction), t= %.12lf, f1= %.12lf,f2= %.12lf,f3= %.12lf, del= %.12lf\n",directest, t, fp,(*fret),fptt, del);
           for(i=1, gp[h][j]=0.;i<=nlstate;i++)          fprintf(ficlog,"f1-2f2+f3= %.12lf, f1-f2-del= %.12lf, f1-f3= %.12lf\n",fp-2.0*(*fret)+fptt, fp -(*fret) -del, fp-fptt);
             gp[h][j] += prlim[i][i]*p3mat[i][j][h];        } 
         }        if (directest < 0.0) { /* Then we use it for new direction */
       }  #endif
       /* This for computing forces of mortality (h=1)as a weighted average */  #ifdef DEBUGLINMIN
       for(j=nlstate+1,gpp[j]=0.;j<=nlstate+ndeath;j++){          printf("Before linmin in direction P%d-P0\n",n);
         for(i=1; i<= nlstate; i++)          for (j=1;j<=n;j++) { 
           gpp[j] += prlim[i][i]*p3mat[i][j][1];            printf(" Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
       }                fprintf(ficlog," Before xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
       /* end force of mortality */            if(j % ncovmodel == 0){
               printf("\n");
       for(i=1; i<=npar; i++) /* Computes gradient */              fprintf(ficlog,"\n");
         xp[i] = x[i] - (i==theta ?delti[theta]:0);            }
       hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);            }
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);  #endif
            linmin(p,xit,n,fret,func); /* computes minimum on the extrapolated direction: changes p and rescales xit.*/
       if (popbased==1) {  #ifdef DEBUGLINMIN
         for(i=1; i<=nlstate;i++)          for (j=1;j<=n;j++) { 
           prlim[i][i]=probs[(int)age][i][ij];            printf("After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
       }            fprintf(ficlog,"After xit[%d]= %12.7f p[%d]= %12.7f",j,xit[j],j,p[j]);
             if(j % ncovmodel == 0){
       for(j=1; j<= nlstate; j++){              printf("\n");
         for(h=0; h<=nhstepm; h++){              fprintf(ficlog,"\n");
           for(i=1, gm[h][j]=0.;i<=nlstate;i++)            }
             gm[h][j] += prlim[i][i]*p3mat[i][j][h];          }
         }  #endif
       }          for (j=1;j<=n;j++) { 
       /* This for computing force of mortality (h=1)as a weighted average */            xi[j][ibig]=xi[j][n]; /* Replace direction with biggest decrease by last direction n */
       for(j=nlstate+1,gmp[j]=0.;j<=nlstate+ndeath;j++){            xi[j][n]=xit[j];      /* and this nth direction by the by the average p_0 p_n */
         for(i=1; i<= nlstate; i++)          }
           gmp[j] += prlim[i][i]*p3mat[i][j][1];          printf("Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
       }              fprintf(ficlog,"Gaining to use new average direction of P0 P%d instead of biggest increase direction %d :\n",n,ibig);
       /* end force of mortality */  
   #ifdef DEBUG
       for(j=1; j<= nlstate; j++) /* vareij */          printf("Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
         for(h=0; h<=nhstepm; h++){          fprintf(ficlog,"Direction changed  last moved %d in place of ibig=%d, new last is the average:\n",n,ibig);
           gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];          for(j=1;j<=n;j++){
         }            printf(" %.12e",xit[j]);
       for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */            fprintf(ficlog," %.12e",xit[j]);
         gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];          }
       }          printf("\n");
           fprintf(ficlog,"\n");
     } /* End theta */  #endif
         } /* end of t or directest negative */
     trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */  #ifdef POWELLF1F3
   #else
     for(h=0; h<=nhstepm; h++) /* veij */      } /* end if (fptt < fp)  */
       for(j=1; j<=nlstate;j++)  #endif
         for(theta=1; theta <=npar; theta++)    } /* loop iteration */ 
           trgradg[h][j][theta]=gradg[h][theta][j];  } 
   
     for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */  /**** Prevalence limit (stable or period prevalence)  ****************/
       for(theta=1; theta <=npar; theta++)  
         trgradgp[j][theta]=gradgp[theta][j];  double **prevalim(double **prlim, int nlstate, double x[], double age, double **oldm, double **savm, double ftolpl, int *ncvyear, int ij)
   {
     hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */    /* Computes the prevalence limit in each live state at age x by left multiplying the unit
     for(i=1;i<=nlstate;i++)       matrix by transitions matrix until convergence is reached with precision ftolpl */
       for(j=1;j<=nlstate;j++)    /* Wx= Wx-1 Px-1= Wx-2 Px-2 Px-1  = Wx-n Px-n ... Px-2 Px-1 I */
         vareij[i][j][(int)age] =0.;    /* Wx is row vector: population in state 1, population in state 2, population dead */
     /* or prevalence in state 1, prevalence in state 2, 0 */
     for(h=0;h<=nhstepm;h++){    /* newm is the matrix after multiplications, its rows are identical at a factor */
       for(k=0;k<=nhstepm;k++){    /* Initial matrix pimij */
         matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);    /* {0.85204250825084937, 0.13044499163996345, 0.017512500109187184, */
         matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);    /* 0.090851990222114765, 0.88271245433047185, 0.026435555447413338, */
         for(i=1;i<=nlstate;i++)    /*  0,                   0                  , 1} */
           for(j=1;j<=nlstate;j++)    /*
             vareij[i][j][(int)age] += doldm[i][j]*hf*hf;     * and after some iteration: */
       }    /* {0.45504275246439968, 0.42731458730878791, 0.11764266022681241, */
     }    /*  0.45201005341706885, 0.42865420071559901, 0.11933574586733192, */
     /*  0,                   0                  , 1} */
     /* pptj */    /* And prevalence by suppressing the deaths are close to identical rows in prlim: */
     matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);    /* {0.51571254859325999, 0.4842874514067399, */
     matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);    /*  0.51326036147820708, 0.48673963852179264} */
     for(j=nlstate+1;j<=nlstate+ndeath;j++)    /* If we start from prlim again, prlim tends to a constant matrix */
       for(i=nlstate+1;i<=nlstate+ndeath;i++)  
         varppt[j][i]=doldmp[j][i];    int i, ii,j,k;
     /* end ppptj */    double *min, *max, *meandiff, maxmax,sumnew=0.;
     hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij);      /* double **matprod2(); */ /* test */
     prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ij);    double **out, cov[NCOVMAX+1], **pmij();
      double **newm;
     if (popbased==1) {    double agefin, delaymax=200. ; /* 100 Max number of years to converge */
       for(i=1; i<=nlstate;i++)    int ncvloop=0;
         prlim[i][i]=probs[(int)age][i][ij];    
     }    min=vector(1,nlstate);
        max=vector(1,nlstate);
     /* This for computing force of mortality (h=1)as a weighted average */    meandiff=vector(1,nlstate);
     for(j=nlstate+1,gmp[j]=0.;j<=nlstate+ndeath;j++){  
       for(i=1; i<= nlstate; i++)    for (ii=1;ii<=nlstate+ndeath;ii++)
         gmp[j] += prlim[i][i]*p3mat[i][j][1];      for (j=1;j<=nlstate+ndeath;j++){
     }            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
     /* end force of mortality */      }
     
     fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);    cov[1]=1.;
     for(j=nlstate+1; j<=(nlstate+ndeath);j++){    
       fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));    /* Even if hstepm = 1, at least one multiplication by the unit matrix */
       for(i=1; i<=nlstate;i++){    /* Start at agefin= age, computes the matrix of passage and loops decreasing agefin until convergence is reached */
         fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);    for(agefin=age-stepm/YEARM; agefin>=age-delaymax; agefin=agefin-stepm/YEARM){
       }      ncvloop++;
     }      newm=savm;
     fprintf(ficresprobmorprev,"\n");      /* Covariates have to be included here again */
       cov[2]=agefin;
     fprintf(ficresvij,"%.0f ",age );      if(nagesqr==1)
     for(i=1; i<=nlstate;i++)        cov[3]= agefin*agefin;;
       for(j=1; j<=nlstate;j++){      for (k=1; k<=cptcovn;k++) {
         fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);        /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
       }        cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
     fprintf(ficresvij,"\n");        /* printf("prevalim ij=%d k=%d Tvar[%d]=%d nbcode=%d cov=%lf codtabm(%d,Tvar[%d])=%d \n",ij,k, k, Tvar[k],nbcode[Tvar[k]][codtabm(ij,Tvar[k])],cov[2+k], ij, k, codtabm(ij,Tvar[k])]); */
     free_matrix(gp,0,nhstepm,1,nlstate);      }
     free_matrix(gm,0,nhstepm,1,nlstate);      /*wrong? for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
     free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);      /* for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]*cov[2]; */
     free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);      for (k=1; k<=cptcovage;k++) cov[2+nagesqr+Tage[k]]=nbcode[Tvar[k]][codtabm(ij,k)]*cov[2];
     free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      for (k=1; k<=cptcovprod;k++) /* Useless */
   } /* End age */        /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])] * nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
   free_vector(gpp,nlstate+1,nlstate+ndeath);        cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)] * nbcode[Tvard[k][2]][codtabm(ij,k)];
   free_vector(gmp,nlstate+1,nlstate+ndeath);      
   free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);      /*printf("ij=%d cptcovprod=%d tvar=%d ", ij, cptcovprod, Tvar[1]);*/
   free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/      /*printf("ij=%d cov[3]=%lf cov[4]=%lf \n",ij, cov[3],cov[4]);*/
   fprintf(ficgp,"\nset noparametric;set nolabel; set ter png small;set size 0.65, 0.65");      /*printf("ij=%d cov[3]=%lf \n",ij, cov[3]);*/
   /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */      /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
   fprintf(ficgp,"\n set log y; set nolog x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");      /* out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /\* Bug Valgrind *\/ */
   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm);      out=matprod2(newm, pmij(pmmij,cov,ncovmodel,x,nlstate),1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, oldm); /* Bug Valgrind */
   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm);      
   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm);      savm=oldm;
   fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",fileresprobmorprev,fileresprobmorprev);      oldm=newm;
   fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.png\"> <br>\n", stepm,YEARM,digitp,digit);  
   fprintf(ficgp,"\nset out \"varmuptjgr%s%s.png\";replot;",digitp,digit);      for(j=1; j<=nlstate; j++){
         max[j]=0.;
   free_vector(xp,1,npar);        min[j]=1.;
   free_matrix(doldm,1,nlstate,1,nlstate);      }
   free_matrix(dnewm,1,nlstate,1,npar);      for(i=1;i<=nlstate;i++){
   free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);        sumnew=0;
   free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);        for(k=1; k<=ndeath; k++) sumnew+=newm[i][nlstate+k];
   free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);        for(j=1; j<=nlstate; j++){ 
   fclose(ficresprobmorprev);          prlim[i][j]= newm[i][j]/(1-sumnew);
   fclose(ficgp);          max[j]=FMAX(max[j],prlim[i][j]);
   fclose(fichtm);          min[j]=FMIN(min[j],prlim[i][j]);
         }
 }      }
   
 /************ Variance of prevlim ******************/      maxmax=0.;
 void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int ij)      for(j=1; j<=nlstate; j++){
 {        meandiff[j]=(max[j]-min[j])/(max[j]+min[j])*2.; /* mean difference for each column */
   /* Variance of prevalence limit */        maxmax=FMAX(maxmax,meandiff[j]);
   /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/        /* printf(" age= %d meandiff[%d]=%f, agefin=%d max[%d]=%f min[%d]=%f maxmax=%f\n", (int)age, j, meandiff[j],(int)agefin, j, max[j], j, min[j],maxmax); */
   double **newm;      } /* j loop */
   double **dnewm,**doldm;      *ncvyear= (int)age- (int)agefin;
   int i, j, nhstepm, hstepm;      /* printf("maxmax=%lf maxmin=%lf ncvloop=%d, age=%d, agefin=%d ncvyear=%d \n", maxmax, maxmin, ncvloop, (int)age, (int)agefin, *ncvyear); */
   int k, cptcode;      if(maxmax < ftolpl){
   double *xp;        /* printf("maxmax=%lf ncvloop=%ld, age=%d, agefin=%d ncvyear=%d \n", maxmax, ncvloop, (int)age, (int)agefin, *ncvyear); */
   double *gp, *gm;        free_vector(min,1,nlstate);
   double **gradg, **trgradg;        free_vector(max,1,nlstate);
   double age,agelim;        free_vector(meandiff,1,nlstate);
   int theta;        return prlim;
          }
   fprintf(ficresvpl,"# Standard deviation of prevalence's limit\n");    } /* age loop */
   fprintf(ficresvpl,"# Age");      /* After some age loop it doesn't converge */
   for(i=1; i<=nlstate;i++)    printf("Warning: the stable prevalence at age %d did not converge with the required precision (%g > ftolpl=%g) within %.0f years. Try to lower 'ftolpl'. \n\
       fprintf(ficresvpl," %1d-%1d",i,i);  Earliest age to start was %d-%d=%d, ncvloop=%d, ncvyear=%d\n", (int)age, maxmax, ftolpl, delaymax, (int)age, (int)delaymax, (int)agefin, ncvloop, *ncvyear);
   fprintf(ficresvpl,"\n");    /* Try to lower 'ftol', for example from 1.e-8 to 6.e-9.\n", ftolpl, (int)age, (int)delaymax, (int)agefin, ncvloop, (int)age-(int)agefin); */
     free_vector(min,1,nlstate);
   xp=vector(1,npar);    free_vector(max,1,nlstate);
   dnewm=matrix(1,nlstate,1,npar);    free_vector(meandiff,1,nlstate);
   doldm=matrix(1,nlstate,1,nlstate);    
      return prlim; /* should not reach here */
   hstepm=1*YEARM; /* Every year of age */  }
   hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */  
   agelim = AGESUP;  /*************** transition probabilities ***************/ 
   for (age=bage; age<=fage; age ++){ /* If stepm=6 months */  
     nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */  double **pmij(double **ps, double *cov, int ncovmodel, double *x, int nlstate )
     if (stepm >= YEARM) hstepm=1;  {
     nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */    /* According to parameters values stored in x and the covariate's values stored in cov,
     gradg=matrix(1,npar,1,nlstate);       computes the probability to be observed in state j being in state i by appying the
     gp=vector(1,nlstate);       model to the ncovmodel covariates (including constant and age).
     gm=vector(1,nlstate);       lnpijopii=ln(pij/pii)= aij+bij*age+cij*v1+dij*v2+... = sum_nc=1^ncovmodel xij(nc)*cov[nc]
        and, according on how parameters are entered, the position of the coefficient xij(nc) of the
     for(theta=1; theta <=npar; theta++){       ncth covariate in the global vector x is given by the formula:
       for(i=1; i<=npar; i++){ /* Computes gradient */       j<i nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel
         xp[i] = x[i] + (i==theta ?delti[theta]:0);       j>=i nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel
       }       Computes ln(pij/pii) (lnpijopii), deduces pij/pii by exponentiation,
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);       sums on j different of i to get 1-pii/pii, deduces pii, and then all pij.
       for(i=1;i<=nlstate;i++)       Outputs ps[i][j] the probability to be observed in j being in j according to
         gp[i] = prlim[i][i];       the values of the covariates cov[nc] and corresponding parameter values x[nc+shiftij]
        */
       for(i=1; i<=npar; i++) /* Computes gradient */    double s1, lnpijopii;
         xp[i] = x[i] - (i==theta ?delti[theta]:0);    /*double t34;*/
       prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ij);    int i,j, nc, ii, jj;
       for(i=1;i<=nlstate;i++)  
         gm[i] = prlim[i][i];      for(i=1; i<= nlstate; i++){
         for(j=1; j<i;j++){
       for(i=1;i<=nlstate;i++)          for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
         gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];            /*lnpijopii += param[i][j][nc]*cov[nc];*/
     } /* End theta */            lnpijopii += x[nc+((i-1)*(nlstate+ndeath-1)+j-1)*ncovmodel]*cov[nc];
   /*       printf("Int j<i s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
     trgradg =matrix(1,nlstate,1,npar);          }
           ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
     for(j=1; j<=nlstate;j++)  /*      printf("s1=%.17e, lnpijopii=%.17e\n",s1,lnpijopii); */
       for(theta=1; theta <=npar; theta++)        }
         trgradg[j][theta]=gradg[theta][j];        for(j=i+1; j<=nlstate+ndeath;j++){
           for (nc=1, lnpijopii=0.;nc <=ncovmodel; nc++){
     for(i=1;i<=nlstate;i++)            /*lnpijopii += x[(i-1)*nlstate*ncovmodel+(j-2)*ncovmodel+nc+(i-1)*(ndeath-1)*ncovmodel]*cov[nc];*/
       varpl[i][(int)age] =0.;            lnpijopii += x[nc + ((i-1)*(nlstate+ndeath-1)+(j-2))*ncovmodel]*cov[nc];
     matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);  /*        printf("Int j>i s1=%.17e, lnpijopii=%.17e %lx %lx\n",s1,lnpijopii,s1,lnpijopii); */
     matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);          }
     for(i=1;i<=nlstate;i++)          ps[i][j]=lnpijopii; /* In fact ln(pij/pii) */
       varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */        }
       }
     fprintf(ficresvpl,"%.0f ",age );      
     for(i=1; i<=nlstate;i++)      for(i=1; i<= nlstate; i++){
       fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));        s1=0;
     fprintf(ficresvpl,"\n");        for(j=1; j<i; j++){
     free_vector(gp,1,nlstate);          s1+=exp(ps[i][j]); /* In fact sums pij/pii */
     free_vector(gm,1,nlstate);          /*printf("debug1 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
     free_matrix(gradg,1,npar,1,nlstate);        }
     free_matrix(trgradg,1,nlstate,1,npar);        for(j=i+1; j<=nlstate+ndeath; j++){
   } /* End age */          s1+=exp(ps[i][j]); /* In fact sums pij/pii */
           /*printf("debug2 %d %d ps=%lf exp(ps)=%lf s1+=%lf\n",i,j,ps[i][j],exp(ps[i][j]),s1); */
   free_vector(xp,1,npar);        }
   free_matrix(doldm,1,nlstate,1,npar);        /* s1= sum_{j<>i} pij/pii=(1-pii)/pii and thus pii is known from s1 */
   free_matrix(dnewm,1,nlstate,1,nlstate);        ps[i][i]=1./(s1+1.);
         /* Computing other pijs */
 }        for(j=1; j<i; j++)
           ps[i][j]= exp(ps[i][j])*ps[i][i];
 /************ Variance of one-step probabilities  ******************/        for(j=i+1; j<=nlstate+ndeath; j++)
 void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax)          ps[i][j]= exp(ps[i][j])*ps[i][i];
 {        /* ps[i][nlstate+1]=1.-s1- ps[i][i];*/ /* Sum should be 1 */
   int i, j=0,  i1, k1, l1, t, tj;      } /* end i */
   int k2, l2, j1,  z1;      
   int k=0,l, cptcode;      for(ii=nlstate+1; ii<= nlstate+ndeath; ii++){
   int first=1, first1;        for(jj=1; jj<= nlstate+ndeath; jj++){
   double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2;          ps[ii][jj]=0;
   double **dnewm,**doldm;          ps[ii][ii]=1;
   double *xp;        }
   double *gp, *gm;      }
   double **gradg, **trgradg;      
   double **mu;      
   double age,agelim, cov[NCOVMAX];      /* for(ii=1; ii<= nlstate+ndeath; ii++){ */
   double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */      /*   for(jj=1; jj<= nlstate+ndeath; jj++){ */
   int theta;      /*  printf(" pmij  ps[%d][%d]=%lf ",ii,jj,ps[ii][jj]); */
   char fileresprob[FILENAMELENGTH];      /*   } */
   char fileresprobcov[FILENAMELENGTH];      /*   printf("\n "); */
   char fileresprobcor[FILENAMELENGTH];      /* } */
       /* printf("\n ");printf("%lf ",cov[2]);*/
   double ***varpij;      /*
         for(i=1; i<= npar; i++) printf("%f ",x[i]);
   strcpy(fileresprob,"prob");        goto end;*/
   strcat(fileresprob,fileres);      return ps;
   if((ficresprob=fopen(fileresprob,"w"))==NULL) {  }
     printf("Problem with resultfile: %s\n", fileresprob);  
     fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);  /**************** Product of 2 matrices ******************/
   }  
   strcpy(fileresprobcov,"probcov");  double **matprod2(double **out, double **in,int nrl, int nrh, int ncl, int nch, int ncolol, int ncoloh, double **b)
   strcat(fileresprobcov,fileres);  {
   if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {    /* Computes the matrix product of in(1,nrh-nrl+1)(1,nch-ncl+1) times
     printf("Problem with resultfile: %s\n", fileresprobcov);       b(1,nch-ncl+1)(1,ncoloh-ncolol+1) into out(...) */
     fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);    /* in, b, out are matrice of pointers which should have been initialized 
   }       before: only the contents of out is modified. The function returns
   strcpy(fileresprobcor,"probcor");       a pointer to pointers identical to out */
   strcat(fileresprobcor,fileres);    int i, j, k;
   if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {    for(i=nrl; i<= nrh; i++)
     printf("Problem with resultfile: %s\n", fileresprobcor);      for(k=ncolol; k<=ncoloh; k++){
     fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);        out[i][k]=0.;
   }        for(j=ncl; j<=nch; j++)
   printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);          out[i][k] +=in[i][j]*b[j][k];
   fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);      }
   printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);    return out;
   fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);  }
   printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);  
   fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);  
    /************* Higher Matrix Product ***************/
   fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");  
   fprintf(ficresprob,"# Age");  double ***hpxij(double ***po, int nhstepm, double age, int hstepm, double *x, int nlstate, int stepm, double **oldm, double **savm, int ij )
   fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");  {
   fprintf(ficresprobcov,"# Age");    /* Computes the transition matrix starting at age 'age' over 
   fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");       'nhstepm*hstepm*stepm' months (i.e. until
   fprintf(ficresprobcov,"# Age");       age (in years)  age+nhstepm*hstepm*stepm/12) by multiplying 
        nhstepm*hstepm matrices. 
        Output is stored in matrix po[i][j][h] for h every 'hstepm' step 
   for(i=1; i<=nlstate;i++)       (typically every 2 years instead of every month which is too big 
     for(j=1; j<=(nlstate+ndeath);j++){       for the memory).
       fprintf(ficresprob," p%1d-%1d (SE)",i,j);       Model is determined by parameters x and covariates have to be 
       fprintf(ficresprobcov," p%1d-%1d ",i,j);       included manually here. 
       fprintf(ficresprobcor," p%1d-%1d ",i,j);  
     }         */
   fprintf(ficresprob,"\n");  
   fprintf(ficresprobcov,"\n");    int i, j, d, h, k;
   fprintf(ficresprobcor,"\n");    double **out, cov[NCOVMAX+1];
   xp=vector(1,npar);    double **newm;
   dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);    double agexact;
   doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));  
   mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);    /* Hstepm could be zero and should return the unit matrix */
   varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);    for (i=1;i<=nlstate+ndeath;i++)
   first=1;      for (j=1;j<=nlstate+ndeath;j++){
   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) {        oldm[i][j]=(i==j ? 1.0 : 0.0);
     printf("Problem with gnuplot file: %s\n", optionfilegnuplot);        po[i][j][0]=(i==j ? 1.0 : 0.0);
     fprintf(ficlog,"Problem with gnuplot file: %s\n", optionfilegnuplot);      }
     exit(0);    /* Even if hstepm = 1, at least one multiplication by the unit matrix */
   }    for(h=1; h <=nhstepm; h++){
   else{      for(d=1; d <=hstepm; d++){
     fprintf(ficgp,"\n# Routine varprob");        newm=savm;
   }        /* Covariates have to be included here again */
   if((fichtm=fopen(optionfilehtm,"a"))==NULL) {        cov[1]=1.;
     printf("Problem with html file: %s\n", optionfilehtm);        agexact=age+((h-1)*hstepm + (d-1))*stepm/YEARM;
     fprintf(ficlog,"Problem with html file: %s\n", optionfilehtm);        cov[2]=agexact;
     exit(0);        if(nagesqr==1)
   }          cov[3]= agexact*agexact;
   else{        for (k=1; k<=cptcovn;k++) 
     fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");          cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,k)];
     fprintf(fichtm,"\n");          /* cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
         for (k=1; k<=cptcovage;k++) /* Should start at cptcovn+1 */
     fprintf(fichtm,"\n<li><h4> Computing matrix of variance-covariance of step probabilities</h4></li>\n");          /* cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
     fprintf(fichtm,"\nWe have drawn ellipsoids of confidence around the p<inf>ij</inf>, p<inf>kl</inf> to understand the covariance between two incidences. They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");          cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
     fprintf(fichtm,"\n<br> We have drawn x'cov<sup>-1</sup>x = 4 where x is the column vector (pij,pkl). It means that if pij and pkl where uncorrelated the (2X2) matrix would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 standard deviations wide on each axis. <br> When both incidences are correlated we diagonalised the inverse of the covariance matrix and made the appropriate rotation.<br> \n");          /* cov[2+nagesqr+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k]])]*cov[2]; */
         for (k=1; k<=cptcovprod;k++) /* Useless because included in cptcovn */
   }          cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
           /* cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,Tvard[k][1])]*nbcode[Tvard[k][2]][codtabm(ij,Tvard[k][2])]; */
    
   cov[1]=1;  
   tj=cptcoveff;        /*printf("hxi cptcov=%d cptcode=%d\n",cptcov,cptcode);*/
   if (cptcovn<1) {tj=1;ncodemax[1]=1;}        /*printf("h=%d d=%d age=%f cov=%f\n",h,d,age,cov[2]);*/
   j1=0;        out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,1,nlstate+ndeath, 
   for(t=1; t<=tj;t++){                     pmij(pmmij,cov,ncovmodel,x,nlstate));
     for(i1=1; i1<=ncodemax[t];i1++){        savm=oldm;
       j1++;        oldm=newm;
            }
       if  (cptcovn>0) {      for(i=1; i<=nlstate+ndeath; i++)
         fprintf(ficresprob, "\n#********** Variable ");        for(j=1;j<=nlstate+ndeath;j++) {
         for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);          po[i][j][h]=newm[i][j];
         fprintf(ficresprob, "**********\n#");          /*if(h==nhstepm) printf("po[%d][%d][%d]=%f ",i,j,h,po[i][j][h]);*/
         fprintf(ficresprobcov, "\n#********** Variable ");        }
         for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);      /*printf("h=%d ",h);*/
         fprintf(ficresprobcov, "**********\n#");    } /* end h */
          /*     printf("\n H=%d \n",h); */
         fprintf(ficgp, "\n#********** Variable ");    return po;
         for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, "# V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);  }
         fprintf(ficgp, "**********\n#");  
          #ifdef NLOPT
            double  myfunc(unsigned n, const double *p1, double *grad, void *pd){
         fprintf(fichtm, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable ");    double fret;
         for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);    double *xt;
         fprintf(fichtm, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");    int j;
            myfunc_data *d2 = (myfunc_data *) pd;
         fprintf(ficresprobcor, "\n#********** Variable ");      /* xt = (p1-1); */
         for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtab[j1][z1]]);    xt=vector(1,n); 
         fprintf(ficgp, "**********\n#");        for (j=1;j<=n;j++)   xt[j]=p1[j-1]; /* xt[1]=p1[0] */
       }  
          fret=(d2->function)(xt); /*  p xt[1]@8 is fine */
       for (age=bage; age<=fage; age ++){    /* fret=(*func)(xt); /\*  p xt[1]@8 is fine *\/ */
         cov[2]=age;    printf("Function = %.12lf ",fret);
         for (k=1; k<=cptcovn;k++) {    for (j=1;j<=n;j++) printf(" %d %.8lf", j, xt[j]); 
           cov[2+k]=nbcode[Tvar[k]][codtab[j1][Tvar[k]]];    printf("\n");
         }   free_vector(xt,1,n);
         for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2];    return fret;
         for (k=1; k<=cptcovprod;k++)  }
           cov[2+Tprod[k]]=nbcode[Tvard[k][1]][codtab[ij][Tvard[k][1]]]*nbcode[Tvard[k][2]][codtab[ij][Tvard[k][2]]];  #endif
          
         gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));  /*************** log-likelihood *************/
         trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);  double func( double *x)
         gp=vector(1,(nlstate)*(nlstate+ndeath));  {
         gm=vector(1,(nlstate)*(nlstate+ndeath));    int i, ii, j, k, mi, d, kk;
        double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
         for(theta=1; theta <=npar; theta++){    double **out;
           for(i=1; i<=npar; i++)    double sw; /* Sum of weights */
             xp[i] = x[i] + (i==theta ?delti[theta]:0);    double lli; /* Individual log likelihood */
              int s1, s2;
           pmij(pmmij,cov,ncovmodel,xp,nlstate);    double bbh, survp;
              long ipmx;
           k=0;    double agexact;
           for(i=1; i<= (nlstate); i++){    /*extern weight */
             for(j=1; j<=(nlstate+ndeath);j++){    /* We are differentiating ll according to initial status */
               k=k+1;    /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
               gp[k]=pmmij[i][j];    /*for(i=1;i<imx;i++) 
             }      printf(" %d\n",s[4][i]);
           }    */
            
           for(i=1; i<=npar; i++)    ++countcallfunc;
             xp[i] = x[i] - (i==theta ?delti[theta]:0);  
        cov[1]=1.;
           pmij(pmmij,cov,ncovmodel,xp,nlstate);  
           k=0;    for(k=1; k<=nlstate; k++) ll[k]=0.;
           for(i=1; i<=(nlstate); i++){  
             for(j=1; j<=(nlstate+ndeath);j++){    if(mle==1){
               k=k+1;      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
               gm[k]=pmmij[i][j];        /* Computes the values of the ncovmodel covariates of the model
             }           depending if the covariates are fixed or variying (age dependent) and stores them in cov[]
           }           Then computes with function pmij which return a matrix p[i][j] giving the elementary probability
                 to be observed in j being in i according to the model.
           for(i=1; i<= (nlstate)*(nlstate+ndeath); i++)         */
             gradg[theta][i]=(gp[i]-gm[i])/2./delti[theta];          for (k=1; k<=cptcovn;k++){ /* Simple and product covariates without age* products */
         }            cov[2+nagesqr+k]=covar[Tvar[k]][i];
         }
         for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)        /* In model V2+V1*V4+age*V3+V3*V2 Tvar[1] is V2, Tvar[2=V1*V4] 
           for(theta=1; theta <=npar; theta++)           is 6, Tvar[3=age*V3] should not be computed because of age Tvar[4=V3*V2] 
             trgradg[j][theta]=gradg[theta][j];           has been calculated etc */
                for(mi=1; mi<= wav[i]-1; mi++){
         matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov);          for (ii=1;ii<=nlstate+ndeath;ii++)
         matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);            for (j=1;j<=nlstate+ndeath;j++){
                      oldm[ii][j]=(ii==j ? 1.0 : 0.0);
         pmij(pmmij,cov,ncovmodel,x,nlstate);              savm[ii][j]=(ii==j ? 1.0 : 0.0);
                    }
         k=0;          for(d=0; d<dh[mi][i]; d++){
         for(i=1; i<=(nlstate); i++){            newm=savm;
           for(j=1; j<=(nlstate+ndeath);j++){            agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
             k=k+1;            cov[2]=agexact;
             mu[k][(int) age]=pmmij[i][j];            if(nagesqr==1)
           }              cov[3]= agexact*agexact;
         }            for (kk=1; kk<=cptcovage;kk++) {
         for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact; /* Tage[kk] gives the data-covariate associated with age */
           for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)            }
             varpij[i][j][(int)age] = doldm[i][j];            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
                          1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
         /*printf("\n%d ",(int)age);            savm=oldm;
      for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){            oldm=newm;
        printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));          } /* end mult */
        fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));        
      }*/          /*lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]);*/ /* Original formula */
           /* But now since version 0.9 we anticipate for bias at large stepm.
         fprintf(ficresprob,"\n%d ",(int)age);           * If stepm is larger than one month (smallest stepm) and if the exact delay 
         fprintf(ficresprobcov,"\n%d ",(int)age);           * (in months) between two waves is not a multiple of stepm, we rounded to 
         fprintf(ficresprobcor,"\n%d ",(int)age);           * the nearest (and in case of equal distance, to the lowest) interval but now
            * we keep into memory the bias bh[mi][i] and also the previous matrix product
         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)           * (i.e to dh[mi][i]-1) saved in 'savm'. Then we inter(extra)polate the
           fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));           * probability in order to take into account the bias as a fraction of the way
         for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){           * from savm to out if bh is negative or even beyond if bh is positive. bh varies
           fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);           * -stepm/2 to stepm/2 .
           fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);           * For stepm=1 the results are the same as for previous versions of Imach.
         }           * For stepm > 1 the results are less biased than in previous versions. 
         i=0;           */
         for (k=1; k<=(nlstate);k++){          s1=s[mw[mi][i]][i];
           for (l=1; l<=(nlstate+ndeath);l++){          s2=s[mw[mi+1][i]][i];
             i=i++;          bbh=(double)bh[mi][i]/(double)stepm; 
             fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);          /* bias bh is positive if real duration
             fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);           * is higher than the multiple of stepm and negative otherwise.
             for (j=1; j<=i;j++){           */
               fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);          /* lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2]));*/
               fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));          if( s2 > nlstate){ 
             }            /* i.e. if s2 is a death state and if the date of death is known 
           }               then the contribution to the likelihood is the probability to 
         }/* end of loop for state */               die between last step unit time and current  step unit time, 
       } /* end of loop for age */               which is also equal to probability to die before dh 
                minus probability to die before dh-stepm . 
       /* Confidence intervalle of pij  */               In version up to 0.92 likelihood was computed
       /*          as if date of death was unknown. Death was treated as any other
       fprintf(ficgp,"\nset noparametric;unset label");          health state: the date of the interview describes the actual state
       fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");          and not the date of a change in health state. The former idea was
       fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");          to consider that at each interview the state was recorded
       fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);          (healthy, disable or death) and IMaCh was corrected; but when we
       fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);          introduced the exact date of death then we should have modified
       fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);          the contribution of an exact death to the likelihood. This new
       fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);          contribution is smaller and very dependent of the step unit
       */          stepm. It is no more the probability to die between last interview
           and month of death but the probability to survive from last
       /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/          interview up to one month before death multiplied by the
       first1=1;          probability to die within a month. Thanks to Chris
       for (k1=1; k1<=(nlstate);k1++){          Jackson for correcting this bug.  Former versions increased
         for (l1=1; l1<=(nlstate+ndeath);l1++){          mortality artificially. The bad side is that we add another loop
           if(l1==k1) continue;          which slows down the processing. The difference can be up to 10%
           i=(k1-1)*(nlstate+ndeath)+l1;          lower mortality.
           for (k2=1; k2<=(nlstate);k2++){            */
             for (l2=1; l2<=(nlstate+ndeath);l2++){          /* If, at the beginning of the maximization mostly, the
               if(l2==k2) continue;             cumulative probability or probability to be dead is
               j=(k2-1)*(nlstate+ndeath)+l2;             constant (ie = 1) over time d, the difference is equal to
               if(j<=i) continue;             0.  out[s1][3] = savm[s1][3]: probability, being at state
               for (age=bage; age<=fage; age ++){             s1 at precedent wave, to be dead a month before current
                 if ((int)age %5==0){             wave is equal to probability, being at state s1 at
                   v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;             precedent wave, to be dead at mont of the current
                   v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;             wave. Then the observed probability (that this person died)
                   cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;             is null according to current estimated parameter. In fact,
                   mu1=mu[i][(int) age]/stepm*YEARM ;             it should be very low but not zero otherwise the log go to
                   mu2=mu[j][(int) age]/stepm*YEARM;             infinity.
                   /* Computing eigen value of matrix of covariance */          */
                   lc1=(v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12));  /* #ifdef INFINITYORIGINAL */
                   lc2=(v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12));  /*          lli=log(out[s1][s2] - savm[s1][s2]); */
                   if(first1==1){  /* #else */
                     first1=0;  /*        if ((out[s1][s2] - savm[s1][s2]) < mytinydouble)  */
                     printf("Var %.4e %.4e cov %.4e Eigen %.3e %.3e\nOthers in log...\n",v1,v2,cv12,lc1,lc2);  /*          lli=log(mytinydouble); */
                   }  /*        else */
                   fprintf(ficlog,"Var %.4e %.4e cov %.4e Eigen %.3e %.3e\n",v1,v2,cv12,lc1,lc2);  /*          lli=log(out[s1][s2] - savm[s1][s2]); */
                   /* Eigen vectors */  /* #endif */
                   v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));              lli=log(out[s1][s2] - savm[s1][s2]);
                   v21=sqrt(1.-v11*v11);  
                   v12=-v21;          } else if  (s2==-2) {
                   v22=v11;            for (j=1,survp=0. ; j<=nlstate; j++) 
                   /*printf(fignu*/              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                   /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */            /*survp += out[s1][j]; */
                   /* mu2+ v21*lc1*cost + v21*lc2*sin(t) */            lli= log(survp);
                   if(first==1){          }
                     first=0;          
                     fprintf(ficgp,"\nset parametric;set nolabel");          else if  (s2==-4) { 
                     fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k2,l2,k1,l1);            for (j=3,survp=0. ; j<=nlstate; j++)  
                     fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                     fprintf(fichtm,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup> :<a href=\"varpijgr%s%d%1d%1d-%1d%1d.png\">varpijgr%s%d%1d%1d-%1d%1d.png</A>, ",k2,l2,k1,l1,optionfilefiname, j1,k2,l2,k1,l1,optionfilefiname, j1,k2,l2,k1,l1);            lli= log(survp); 
                     fprintf(fichtm,"\n<br><img src=\"varpijgr%s%d%1d%1d-%1d%1d.png\"> ",optionfilefiname, j1,k2,l2,k1,l1);          } 
                     fprintf(ficgp,"\nset out \"varpijgr%s%d%1d%1d-%1d%1d.png\"",optionfilefiname, j1,k2,l2,k1,l1);  
                     fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu2,mu1);          else if  (s2==-5) { 
                     fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k2,l2,k1,l1);            for (j=1,survp=0. ; j<=2; j++)  
                     /*              fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(-%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) t \"%d\"",\              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
                             mu2,std,v21,sqrt(lc1),v21,sqrt(lc2), \            lli= log(survp); 
                             mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),(int) age);          } 
                     */          
                     fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(-%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\          else{
                             mu2,std,v21,sqrt(lc1),v21,sqrt(lc2), \            lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
                             mu1,std,v11,sqrt(lc1),v12,sqrt(lc2));            /*  lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2]));*/ /* linear interpolation */
                   }else{          } 
                     first=0;          /*lli=(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]);*/
                     fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k2,l2,k1,l1);          /*if(lli ==000.0)*/
                     fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu2,mu1);          /*printf("bbh= %f lli=%f savm=%f out=%f %d\n",bbh,lli,savm[s1][s2], out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]],i); */
                     /*          ipmx +=1;
                     fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(-%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) t \"%d\"",\          sw += weight[i];
                             mu2,std,v21,sqrt(lc1),v21,sqrt(lc2), \          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                             mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),(int) age);          /* if (lli < log(mytinydouble)){ */
                     */          /*   printf("Close to inf lli = %.10lf <  %.10lf i= %d mi= %d, s[%d][i]=%d s1=%d s2=%d\n", lli,log(mytinydouble), i, mi,mw[mi][i], s[mw[mi][i]][i], s1,s2); */
                     fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(-%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\          /*   fprintf(ficlog,"Close to inf lli = %.10lf i= %d mi= %d, s[mw[mi][i]][i]=%d\n", lli, i, mi,s[mw[mi][i]][i]); */
                             mu2,std,v21,sqrt(lc1),v21,sqrt(lc2), \          /* } */
                             mu1,std,v11,sqrt(lc1),v12,sqrt(lc2));        } /* end of wave */
                   }/* if first */      } /* end of individual */
                 } /* age mod 5 */    }  else if(mle==2){
               } /* end loop age */      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
               fprintf(ficgp,"\nset out \"varpijgr%s%d%1d%1d-%1d%1d.png\";replot;",optionfilefiname, j1,k2,l2,k1,l1);        for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
               first=1;        for(mi=1; mi<= wav[i]-1; mi++){
             } /*l12 */          for (ii=1;ii<=nlstate+ndeath;ii++)
           } /* k12 */            for (j=1;j<=nlstate+ndeath;j++){
         } /*l1 */              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
       }/* k1 */              savm[ii][j]=(ii==j ? 1.0 : 0.0);
     } /* loop covariates */            }
     free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);          for(d=0; d<=dh[mi][i]; d++){
     free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));            newm=savm;
     free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));            agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
     free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);            cov[2]=agexact;
     free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);            if(nagesqr==1)
     free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);              cov[3]= agexact*agexact;
   }            for (kk=1; kk<=cptcovage;kk++) {
   free_vector(xp,1,npar);              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
   fclose(ficresprob);            }
   fclose(ficresprobcov);            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
   fclose(ficresprobcor);                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
   fclose(ficgp);            savm=oldm;
   fclose(fichtm);            oldm=newm;
 }          } /* end mult */
         
           s1=s[mw[mi][i]][i];
 /******************* Printing html file ***********/          s2=s[mw[mi+1][i]][i];
 void printinghtml(char fileres[], char title[], char datafile[], int firstpass, \          bbh=(double)bh[mi][i]/(double)stepm; 
                   int lastpass, int stepm, int weightopt, char model[],\          lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*(savm[s1][s2])):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
                   int imx,int jmin, int jmax, double jmeanint,char rfileres[],\          ipmx +=1;
                   int popforecast, int estepm ,\          sw += weight[i];
                   double jprev1, double mprev1,double anprev1, \          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
                   double jprev2, double mprev2,double anprev2){        } /* end of wave */
   int jj1, k1, i1, cpt;      } /* end of individual */
   /*char optionfilehtm[FILENAMELENGTH];*/    }  else if(mle==3){  /* exponential inter-extrapolation */
   if((fichtm=fopen(optionfilehtm,"a"))==NULL)    {      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
     printf("Problem with %s \n",optionfilehtm), exit(0);        for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
     fprintf(ficlog,"Problem with %s \n",optionfilehtm), exit(0);        for(mi=1; mi<= wav[i]-1; mi++){
   }          for (ii=1;ii<=nlstate+ndeath;ii++)
             for (j=1;j<=nlstate+ndeath;j++){
    fprintf(fichtm,"<ul><li><h4>Result files (first order: no variance)</h4>\n              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
  - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"p%s\">p%s</a> <br>\n              savm[ii][j]=(ii==j ? 1.0 : 0.0);
  - Estimated transition probabilities over %d (stepm) months: <a href=\"pij%s\">pij%s</a><br>\n            }
  - Stable prevalence in each health state: <a href=\"pl%s\">pl%s</a> <br>\n          for(d=0; d<dh[mi][i]; d++){
  - Life expectancies by age and initial health status (estepm=%2d months):            newm=savm;
    <a href=\"e%s\">e%s</a> <br>\n</li>", \            agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
   jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,fileres,fileres,stepm,fileres,fileres,fileres,fileres,estepm,fileres,fileres);            cov[2]=agexact;
             if(nagesqr==1)
 fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");              cov[3]= agexact*agexact;
             for (kk=1; kk<=cptcovage;kk++) {
  m=cptcoveff;              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
  if (cptcovn < 1) {m=1;ncodemax[1]=1;}            }
             out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
  jj1=0;                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
  for(k1=1; k1<=m;k1++){            savm=oldm;
    for(i1=1; i1<=ncodemax[k1];i1++){            oldm=newm;
      jj1++;          } /* end mult */
      if (cptcovn > 0) {        
        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");          s1=s[mw[mi][i]][i];
        for (cpt=1; cpt<=cptcoveff;cpt++)          s2=s[mw[mi+1][i]][i];
          fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);          bbh=(double)bh[mi][i]/(double)stepm; 
        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");          lli= (savm[s1][s2]>1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
      }          ipmx +=1;
      /* Pij */          sw += weight[i];
      fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i %d (stepm) months before: pe%s%d1.png<br>          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
 <img src=\"pe%s%d1.png\">",stepm,strtok(optionfile, "."),jj1,strtok(optionfile, "."),jj1);            } /* end of wave */
      /* Quasi-incidences */      } /* end of individual */
      fprintf(fichtm,"<br>- Pij or Conditional probabilities to be observed in state j being in state i %d (stepm) months before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too: pe%s%d2.png<br>    }else if (mle==4){  /* ml=4 no inter-extrapolation */
 <img src=\"pe%s%d2.png\">",stepm,strtok(optionfile, "."),jj1,strtok(optionfile, "."),jj1);      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
        /* Stable prevalence in each health state */        for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
        for(cpt=1; cpt<nlstate;cpt++){        for(mi=1; mi<= wav[i]-1; mi++){
          fprintf(fichtm,"<br>- Stable prevalence in each health state : p%s%d%d.png<br>          for (ii=1;ii<=nlstate+ndeath;ii++)
 <img src=\"p%s%d%d.png\">",strtok(optionfile, "."),cpt,jj1,strtok(optionfile, "."),cpt,jj1);            for (j=1;j<=nlstate+ndeath;j++){
        }              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
      for(cpt=1; cpt<=nlstate;cpt++) {              savm[ii][j]=(ii==j ? 1.0 : 0.0);
         fprintf(fichtm,"\n<br>- Health life expectancies by age and initial health state (%d): exp%s%d%d.png <br>            }
 <img src=\"exp%s%d%d.png\">",cpt,strtok(optionfile, "."),cpt,jj1,strtok(optionfile, "."),cpt,jj1);          for(d=0; d<dh[mi][i]; d++){
      }            newm=savm;
      fprintf(fichtm,"\n<br>- Total life expectancy by age and            agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
 health expectancies in states (1) and (2): e%s%d.png<br>            cov[2]=agexact;
 <img src=\"e%s%d.png\">",strtok(optionfile, "."),jj1,strtok(optionfile, "."),jj1);            if(nagesqr==1)
    } /* end i1 */              cov[3]= agexact*agexact;
  }/* End k1 */            for (kk=1; kk<=cptcovage;kk++) {
  fprintf(fichtm,"</ul>");              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
             }
           
  fprintf(fichtm,"\n<br><li><h4> Result files (second order: variances)</h4>\n            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
  - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br>\n                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
  - Variance of one-step probabilities: <a href=\"prob%s\">prob%s</a> <br>\n            savm=oldm;
  - Variance-covariance of one-step probabilities: <a href=\"probcov%s\">probcov%s</a> <br>\n            oldm=newm;
  - Correlation matrix of one-step probabilities: <a href=\"probcor%s\">probcor%s</a> <br>\n          } /* end mult */
  - Variances and covariances of life expectancies by age and initial health status (estepm=%d months): <a href=\"v%s\">v%s</a><br>\n        
  - Health expectancies with their variances (no covariance): <a href=\"t%s\">t%s</a> <br>\n          s1=s[mw[mi][i]][i];
  - Standard deviation of stable prevalences: <a href=\"vpl%s\">vpl%s</a> <br>\n",rfileres,rfileres,fileres,fileres,fileres,fileres,fileres,fileres, estepm, fileres,fileres,fileres,fileres,fileres,fileres);          s2=s[mw[mi+1][i]][i];
           if( s2 > nlstate){ 
  if(popforecast==1) fprintf(fichtm,"\n            lli=log(out[s1][s2] - savm[s1][s2]);
  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n          }else{
  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n            lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
         <br>",fileres,fileres,fileres,fileres);          }
  else          ipmx +=1;
    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model);          sw += weight[i];
 fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
   /*      printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
  m=cptcoveff;        } /* end of wave */
  if (cptcovn < 1) {m=1;ncodemax[1]=1;}      } /* end of individual */
     }else{  /* ml=5 no inter-extrapolation no jackson =0.8a */
  jj1=0;      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
  for(k1=1; k1<=m;k1++){        for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
    for(i1=1; i1<=ncodemax[k1];i1++){        for(mi=1; mi<= wav[i]-1; mi++){
      jj1++;          for (ii=1;ii<=nlstate+ndeath;ii++)
      if (cptcovn > 0) {            for (j=1;j<=nlstate+ndeath;j++){
        fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");              oldm[ii][j]=(ii==j ? 1.0 : 0.0);
        for (cpt=1; cpt<=cptcoveff;cpt++)              savm[ii][j]=(ii==j ? 1.0 : 0.0);
          fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtab[jj1][cpt]]);            }
        fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");          for(d=0; d<dh[mi][i]; d++){
      }            newm=savm;
      for(cpt=1; cpt<=nlstate;cpt++) {            agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
        fprintf(fichtm,"<br>- Observed and stationary prevalence (with confident            cov[2]=agexact;
 interval) in state (%d): v%s%d%d.png <br>            if(nagesqr==1)
 <img src=\"v%s%d%d.png\">",cpt,strtok(optionfile, "."),cpt,jj1,strtok(optionfile, "."),cpt,jj1);                cov[3]= agexact*agexact;
      }            for (kk=1; kk<=cptcovage;kk++) {
    } /* end i1 */              cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
  }/* End k1 */            }
  fprintf(fichtm,"</ul>");          
 fclose(fichtm);            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
 }                         1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
             savm=oldm;
 /******************* Gnuplot file **************/            oldm=newm;
 void printinggnuplot(char fileres[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){          } /* end mult */
         
   int m,cpt,k1,i,k,j,jk,k2,k3,ij,l;          s1=s[mw[mi][i]][i];
   int ng;          s2=s[mw[mi+1][i]][i];
   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) {          lli=log(out[s[mw[mi][i]][i]][s[mw[mi+1][i]][i]]); /* Original formula */
     printf("Problem with file %s",optionfilegnuplot);          ipmx +=1;
     fprintf(ficlog,"Problem with file %s",optionfilegnuplot);          sw += weight[i];
   }          ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
           /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]);*/
 #ifdef windows        } /* end of wave */
     fprintf(ficgp,"cd \"%s\" \n",pathc);      } /* end of individual */
 #endif    } /* End of if */
 m=pow(2,cptcoveff);    for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
      /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
  /* 1eme*/    l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
   for (cpt=1; cpt<= nlstate ; cpt ++) {    return -l;
    for (k1=1; k1<= m ; k1 ++) {  }
   
 #ifdef windows  /*************** log-likelihood *************/
      fprintf(ficgp,"\nset out \"v%s%d%d.png\" \n",strtok(optionfile, "."),cpt,k1);  double funcone( double *x)
      fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter png small\nset size 0.65,0.65\nplot [%.f:%.f] \"vpl%s\" every :::%d::%d u 1:2 \"\%%lf",ageminpar,fage,fileres,k1-1,k1-1);  {
 #endif    /* Same as likeli but slower because of a lot of printf and if */
 #ifdef unix    int i, ii, j, k, mi, d, kk;
 fprintf(ficgp,"\nset out \"v%s%d%d.png\" \n",strtok(optionfile, "."),cpt,k1);    double l, ll[NLSTATEMAX+1], cov[NCOVMAX+1];
 fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nplot [%.f:%.f] \"vpl%s\" u 1:2 \"\%%lf",ageminpar,fage,fileres);    double **out;
 #endif    double lli; /* Individual log likelihood */
     double llt;
 for (i=1; i<= nlstate ; i ++) {    int s1, s2;
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");    double bbh, survp;
   else fprintf(ficgp," \%%*lf (\%%*lf)");    double agexact;
 }    /*extern weight */
     fprintf(ficgp,"\" t\"Stationary prevalence\" w l 0,\"vpl%s\" every :::%d::%d u 1:($2+2*$3) \"\%%lf",fileres,k1-1,k1-1);    /* We are differentiating ll according to initial status */
     for (i=1; i<= nlstate ; i ++) {    /*  for (i=1;i<=npar;i++) printf("%f ", x[i]);*/
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");    /*for(i=1;i<imx;i++) 
   else fprintf(ficgp," \%%*lf (\%%*lf)");      printf(" %d\n",s[4][i]);
 }    */
   fprintf(ficgp,"\" t\"95\%% CI\" w l 1,\"vpl%s\" every :::%d::%d u 1:($2-2*$3) \"\%%lf",fileres,k1-1,k1-1);    cov[1]=1.;
      for (i=1; i<= nlstate ; i ++) {  
   if (i==cpt) fprintf(ficgp," \%%lf (\%%lf)");    for(k=1; k<=nlstate; k++) ll[k]=0.;
   else fprintf(ficgp," \%%*lf (\%%*lf)");  
 }      for (i=1,ipmx=0, sw=0.; i<=imx; i++){
      fprintf(ficgp,"\" t\"\" w l 1,\"p%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l 2",fileres,k1-1,k1-1,2+4*(cpt-1));      for (k=1; k<=cptcovn;k++) cov[2+nagesqr+k]=covar[Tvar[k]][i];
 #ifdef unix      for(mi=1; mi<= wav[i]-1; mi++){
 fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65\n");        for (ii=1;ii<=nlstate+ndeath;ii++)
 #endif          for (j=1;j<=nlstate+ndeath;j++){
    }            oldm[ii][j]=(ii==j ? 1.0 : 0.0);
   }            savm[ii][j]=(ii==j ? 1.0 : 0.0);
   /*2 eme*/          }
         for(d=0; d<dh[mi][i]; d++){
   for (k1=1; k1<= m ; k1 ++) {          newm=savm;
     fprintf(ficgp,"\nset out \"e%s%d.png\" \n",strtok(optionfile, "."),k1);          agexact=agev[mw[mi][i]][i]+d*stepm/YEARM;
     fprintf(ficgp,"set ylabel \"Years\" \nset ter png small\nset size 0.65,0.65\nplot [%.f:%.f] ",ageminpar,fage);          cov[2]=agexact;
              if(nagesqr==1)
     for (i=1; i<= nlstate+1 ; i ++) {            cov[3]= agexact*agexact;
       k=2*i;          for (kk=1; kk<=cptcovage;kk++) {
       fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:2 \"\%%lf",fileres,k1-1,k1-1);            cov[Tage[kk]+2+nagesqr]=covar[Tvar[Tage[kk]]][i]*agexact;
       for (j=1; j<= nlstate+1 ; j ++) {          }
   if (j==i) fprintf(ficgp," \%%lf (\%%lf)");  
   else fprintf(ficgp," \%%*lf (\%%*lf)");          /* savm=pmij(pmmij,cov,ncovmodel,x,nlstate); */
 }            out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath,
       if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l ,");                       1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate));
       else fprintf(ficgp,"\" t\"LE in state (%d)\" w l ,",i-1);          /* out=matprod2(newm,oldm,1,nlstate+ndeath,1,nlstate+ndeath, */
     fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2-$3*2) \"\%%lf",fileres,k1-1,k1-1);          /*           1,nlstate+ndeath,pmij(pmmij,cov,ncovmodel,x,nlstate)); */
       for (j=1; j<= nlstate+1 ; j ++) {          savm=oldm;
         if (j==i) fprintf(ficgp," \%%lf (\%%lf)");          oldm=newm;
         else fprintf(ficgp," \%%*lf (\%%*lf)");        } /* end mult */
 }          
       fprintf(ficgp,"\" t\"\" w l 0,");        s1=s[mw[mi][i]][i];
      fprintf(ficgp,"\"t%s\" every :::%d::%d u 1:($2+$3*2) \"\%%lf",fileres,k1-1,k1-1);        s2=s[mw[mi+1][i]][i];
       for (j=1; j<= nlstate+1 ; j ++) {        bbh=(double)bh[mi][i]/(double)stepm; 
   if (j==i) fprintf(ficgp," \%%lf (\%%lf)");        /* bias is positive if real duration
   else fprintf(ficgp," \%%*lf (\%%*lf)");         * is higher than the multiple of stepm and negative otherwise.
 }           */
       if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l 0");        if( s2 > nlstate && (mle <5) ){  /* Jackson */
       else fprintf(ficgp,"\" t\"\" w l 0,");          lli=log(out[s1][s2] - savm[s1][s2]);
     }        } else if  (s2==-2) {
   }          for (j=1,survp=0. ; j<=nlstate; j++) 
              survp += (1.+bbh)*out[s1][j]- bbh*savm[s1][j];
   /*3eme*/          lli= log(survp);
         }else if (mle==1){
   for (k1=1; k1<= m ; k1 ++) {          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
     for (cpt=1; cpt<= nlstate ; cpt ++) {        } else if(mle==2){
       k=2+nlstate*(2*cpt-2);          lli= (savm[s1][s2]>(double)1.e-8 ?log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* linear interpolation */
       fprintf(ficgp,"\nset out \"exp%s%d%d.png\" \n",strtok(optionfile, "."),cpt,k1);        } else if(mle==3){  /* exponential inter-extrapolation */
       fprintf(ficgp,"set ter png small\nset size 0.65,0.65\nplot [%.f:%.f] \"e%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,fileres,k1-1,k1-1,k,cpt);          lli= (savm[s1][s2]>(double)1.e-8 ?(1.+bbh)*log(out[s1][s2])- bbh*log(savm[s1][s2]):log((1.+bbh)*out[s1][s2])); /* exponential inter-extrapolation */
       /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);        } else if (mle==4){  /* mle=4 no inter-extrapolation */
  for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");          lli=log(out[s1][s2]); /* Original formula */
 fprintf(ficgp,"\" t \"e%d1\" w l",cpt);        } else{  /* mle=0 back to 1 */
 fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);          lli= log((1.+bbh)*out[s1][s2]- bbh*savm[s1][s2]); /* linear interpolation */
  for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");          /*lli=log(out[s1][s2]); */ /* Original formula */
 fprintf(ficgp,"\" t \"e%d1\" w l",cpt);        } /* End of if */
         ipmx +=1;
 */        sw += weight[i];
       for (i=1; i< nlstate ; i ++) {        ll[s[mw[mi][i]][i]] += 2*weight[i]*lli;
         fprintf(ficgp," ,\"e%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",fileres,k1-1,k1-1,k+2*i,cpt,i+1);        /*printf("i=%6d s1=%1d s2=%1d mi=%1d mw=%1d dh=%3d prob=%10.6f w=%6.4f out=%10.6f sav=%10.6f\n",i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],out[s1][s2],savm[s1][s2]); */
         if(globpr){
       }          fprintf(ficresilk,"%9ld %6.1f %6d %2d %2d %2d %2d %3d %11.6f %8.4f %8.3f\
     }   %11.6f %11.6f %11.6f ", \
   }                  num[i], agexact, i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],weight[i]*gipmx/gsw,
                    2*weight[i]*lli,out[s1][s2],savm[s1][s2]);
   /* CV preval stat */          for(k=1,llt=0.,l=0.; k<=nlstate; k++){
     for (k1=1; k1<= m ; k1 ++) {            llt +=ll[k]*gipmx/gsw;
     for (cpt=1; cpt<nlstate ; cpt ++) {            fprintf(ficresilk," %10.6f",-ll[k]*gipmx/gsw);
       k=3;          }
       fprintf(ficgp,"\nset out \"p%s%d%d.png\" \n",strtok(optionfile, "."),cpt,k1);          fprintf(ficresilk," %10.6f\n", -llt);
       fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \nset ter png small\nset size 0.65,0.65\nplot [%.f:%.f] \"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",ageminpar,agemaxpar,fileres,k1,k+cpt+1,k+1);        }
       } /* end of wave */
       for (i=1; i< nlstate ; i ++)    } /* end of individual */
         fprintf(ficgp,"+$%d",k+i+1);    for(k=1,l=0.; k<=nlstate; k++) l += ll[k];
       fprintf(ficgp,")) t\"prev(%d,%d)\" w l",cpt,cpt+1);    /* printf("l1=%f l2=%f ",ll[1],ll[2]); */
          l= l*ipmx/sw; /* To get the same order of magnitude as if weight=1 for every body */
       l=3+(nlstate+ndeath)*cpt;    if(globpr==0){ /* First time we count the contributions and weights */
       fprintf(ficgp,",\"pij%s\" u ($1==%d ? ($3):1/0):($%d/($%d",fileres,k1,l+cpt+1,l+1);      gipmx=ipmx;
       for (i=1; i< nlstate ; i ++) {      gsw=sw;
         l=3+(nlstate+ndeath)*cpt;    }
         fprintf(ficgp,"+$%d",l+i+1);    return -l;
       }  }
       fprintf(ficgp,")) t\"prev(%d,%d)\" w l\n",cpt+1,cpt+1);    
     }  
   }    /*************** function likelione ***********/
    void likelione(FILE *ficres,double p[], int npar, int nlstate, int *globpri, long *ipmx, double *sw, double *fretone, double (*funcone)(double []))
   /* proba elementaires */  {
    for(i=1,jk=1; i <=nlstate; i++){    /* This routine should help understanding what is done with 
     for(k=1; k <=(nlstate+ndeath); k++){       the selection of individuals/waves and
       if (k != i) {       to check the exact contribution to the likelihood.
         for(j=1; j <=ncovmodel; j++){       Plotting could be done.
           fprintf(ficgp,"p%d=%f ",jk,p[jk]);     */
           jk++;    int k;
           fprintf(ficgp,"\n");  
         }    if(*globpri !=0){ /* Just counts and sums, no printings */
       }      strcpy(fileresilk,"ILK_"); 
     }      strcat(fileresilk,fileresu);
    }      if((ficresilk=fopen(fileresilk,"w"))==NULL) {
         printf("Problem with resultfile: %s\n", fileresilk);
    for(ng=1; ng<=2;ng++){ /* Number of graphics: first is probabilities second is incidence per year*/        fprintf(ficlog,"Problem with resultfile: %s\n", fileresilk);
      for(jk=1; jk <=m; jk++) {      }
        fprintf(ficgp,"\nset out \"pe%s%d%d.png\" \n",strtok(optionfile, "."),jk,ng);      fprintf(ficresilk, "#individual(line's_record) count age s1 s2 wave# effective_wave# number_of_matrices_product pij weight weight/gpw -2ln(pij)*weight 0pij_x 0pij_(x-stepm) cumulating_loglikeli_by_health_state(reweighted=-2ll*weightXnumber_of_contribs/sum_of_weights) and_total\n");
        if (ng==2)      fprintf(ficresilk, "#num_i age i s1 s2 mi mw dh likeli weight %%weight 2wlli out sav ");
          fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");      /*  i,s1,s2,mi,mw[mi][i],dh[mi][i],exp(lli),weight[i],2*weight[i]*lli,out[s1][s2],savm[s1][s2]); */
        else      for(k=1; k<=nlstate; k++) 
          fprintf(ficgp,"\nset title \"Probability\"\n");        fprintf(ficresilk," -2*gipw/gsw*weight*ll[%d]++",k);
        fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65\nset log y\nplot  [%.f:%.f] ",ageminpar,agemaxpar);      fprintf(ficresilk," -2*gipw/gsw*weight*ll(total)\n");
        i=1;    }
        for(k2=1; k2<=nlstate; k2++) {  
          k3=i;    *fretone=(*funcone)(p);
          for(k=1; k<=(nlstate+ndeath); k++) {    if(*globpri !=0){
            if (k != k2){      fclose(ficresilk);
              if(ng==2)      if (mle ==0)
                fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);        fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with initial parameters and mle = %d.",mle);
              else      else if(mle >=1)
                fprintf(ficgp," exp(p%d+p%d*x",i,i+1);        fprintf(fichtm,"\n<br>File of contributions to the likelihood computed with optimized parameters mle = %d.",mle);
              ij=1;      fprintf(fichtm," You should at least run with mle >= 1 to get starting values corresponding to the optimized parameters in order to visualize the real contribution of each individual/wave: <a href=\"%s\">%s</a><br>\n",subdirf(fileresilk),subdirf(fileresilk));
              for(j=3; j <=ncovmodel; j++) {      
                if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {        
                  fprintf(ficgp,"+p%d*%d*x",i+j-1,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);      for (k=1; k<= nlstate ; k++) {
                  ij++;        fprintf(fichtm,"<br>- Probability p%dj by origin %d and destination j <a href=\"%s-p%dj.png\">%s-p%dj.png</a><br> \
                }  <img src=\"%s-p%dj.png\">",k,k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k,subdirf2(optionfilefiname,"ILK_"),k);
                else      }
                  fprintf(ficgp,"+p%d*%d",i+j-1,nbcode[Tvar[j-2]][codtab[jk][j-2]]);      fprintf(fichtm,"<br>- The function drawn is -2Log(L) in Log scale: by state of origin <a href=\"%s-ori.png\">%s-ori.png</a><br> \
              }  <img src=\"%s-ori.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
              fprintf(ficgp,")/(1");      fprintf(fichtm,"<br>- and by state of destination <a href=\"%s-dest.png\">%s-dest.png</a><br> \
                <img src=\"%s-dest.png\">",subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"),subdirf2(optionfilefiname,"ILK_"));
              for(k1=1; k1 <=nlstate; k1++){        fflush(fichtm);
                fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);    }
                ij=1;    return;
                for(j=3; j <=ncovmodel; j++){  }
                  if(((j-2)==Tage[ij]) &&(ij <=cptcovage)) {  
                    fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][Tvar[j-2]]]);  
                    ij++;  /*********** Maximum Likelihood Estimation ***************/
                  }  
                  else  void mlikeli(FILE *ficres,double p[], int npar, int ncovmodel, int nlstate, double ftol, double (*func)(double []))
                    fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2,nbcode[Tvar[j-2]][codtab[jk][j-2]]);  {
                }    int i,j, iter=0;
                fprintf(ficgp,")");    double **xi;
              }    double fret;
              fprintf(ficgp,") t \"p%d%d\" ", k2,k);    double fretone; /* Only one call to likelihood */
              if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");    /*  char filerespow[FILENAMELENGTH];*/
              i=i+ncovmodel;  
            }  #ifdef NLOPT
          } /* end k */    int creturn;
        } /* end k2 */    nlopt_opt opt;
      } /* end jk */    /* double lb[9] = { -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL, -HUGE_VAL }; /\* lower bounds *\/ */
    } /* end ng */    double *lb;
    fclose(ficgp);    double minf; /* the minimum objective value, upon return */
 }  /* end gnuplot */    double * p1; /* Shifted parameters from 0 instead of 1 */
     myfunc_data dinst, *d = &dinst;
   #endif
 /*************** Moving average **************/  
 void movingaverage(double agedeb, double fage,double ageminpar, double ***mobaverage){  
     xi=matrix(1,npar,1,npar);
   int i, cpt, cptcod;    for (i=1;i<=npar;i++)
     for (agedeb=ageminpar; agedeb<=fage; agedeb++)      for (j=1;j<=npar;j++)
       for (i=1; i<=nlstate;i++)        xi[i][j]=(i==j ? 1.0 : 0.0);
         for (cptcod=1;cptcod<=ncodemax[cptcov];cptcod++)    printf("Powell\n");  fprintf(ficlog,"Powell\n");
           mobaverage[(int)agedeb][i][cptcod]=0.;    strcpy(filerespow,"POW_"); 
        strcat(filerespow,fileres);
     for (agedeb=ageminpar+4; agedeb<=fage; agedeb++){    if((ficrespow=fopen(filerespow,"w"))==NULL) {
       for (i=1; i<=nlstate;i++){      printf("Problem with resultfile: %s\n", filerespow);
         for (cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){      fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
           for (cpt=0;cpt<=4;cpt++){    }
             mobaverage[(int)agedeb-2][i][cptcod]=mobaverage[(int)agedeb-2][i][cptcod]+probs[(int)agedeb-cpt][i][cptcod];    fprintf(ficrespow,"# Powell\n# iter -2*LL");
           }    for (i=1;i<=nlstate;i++)
           mobaverage[(int)agedeb-2][i][cptcod]=mobaverage[(int)agedeb-2][i][cptcod]/5;      for(j=1;j<=nlstate+ndeath;j++)
         }        if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
       }    fprintf(ficrespow,"\n");
     }  #ifdef POWELL
        powell(p,xi,npar,ftol,&iter,&fret,func);
 }  #endif
   
   #ifdef NLOPT
 /************** Forecasting ******************/  #ifdef NEWUOA
 prevforecast(char fileres[], double anproj1,double mproj1,double jproj1,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anproj2,double p[], int i2){    opt = nlopt_create(NLOPT_LN_NEWUOA,npar);
    #else
   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;    opt = nlopt_create(NLOPT_LN_BOBYQA,npar);
   int *popage;  #endif
   double calagedate, agelim, kk1, kk2, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;    lb=vector(0,npar-1);
   double *popeffectif,*popcount;    for (i=0;i<npar;i++) lb[i]= -HUGE_VAL;
   double ***p3mat;    nlopt_set_lower_bounds(opt, lb);
   char fileresf[FILENAMELENGTH];    nlopt_set_initial_step1(opt, 0.1);
     
  agelim=AGESUP;    p1= (p+1); /*  p *(p+1)@8 and p *(p1)@8 are equal p1[0]=p[1] */
 calagedate=(anproj1+mproj1/12.+jproj1/365.-dateintmean)*YEARM;    d->function = func;
     printf(" Func %.12lf \n",myfunc(npar,p1,NULL,d));
   prevalence(ageminpar, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);    nlopt_set_min_objective(opt, myfunc, d);
      nlopt_set_xtol_rel(opt, ftol);
      if ((creturn=nlopt_optimize(opt, p1, &minf)) < 0) {
   strcpy(fileresf,"f");      printf("nlopt failed! %d\n",creturn); 
   strcat(fileresf,fileres);    }
   if((ficresf=fopen(fileresf,"w"))==NULL) {    else {
     printf("Problem with forecast resultfile: %s\n", fileresf);      printf("found minimum after %d evaluations (NLOPT=%d)\n", countcallfunc ,NLOPT);
     fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);      printf("found minimum at f(%g,%g) = %0.10g\n", p[0], p[1], minf);
   }      iter=1; /* not equal */
   printf("Computing forecasting: result on file '%s' \n", fileresf);    }
   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", fileresf);    nlopt_destroy(opt);
   #endif
   if (cptcoveff==0) ncodemax[cptcoveff]=1;    free_matrix(xi,1,npar,1,npar);
     fclose(ficrespow);
   if (mobilav==1) {    printf("\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
     mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);    fprintf(ficlog,"\n#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
     movingaverage(agedeb, fage, ageminpar, mobaverage);    fprintf(ficres,"#Number of iterations & function calls = %d & %d, -2 Log likelihood = %.12f\n",iter, countcallfunc,func(p));
   }  
   }
   stepsize=(int) (stepm+YEARM-1)/YEARM;  
   if (stepm<=12) stepsize=1;  /**** Computes Hessian and covariance matrix ***/
    void hesscov(double **matcov, double **hess, double p[], int npar, double delti[], double ftolhess, double (*func)(double []))
   agelim=AGESUP;  {
      double  **a,**y,*x,pd;
   hstepm=1;    /* double **hess; */
   hstepm=hstepm/stepm;    int i, j;
   yp1=modf(dateintmean,&yp);    int *indx;
   anprojmean=yp;  
   yp2=modf((yp1*12),&yp);    double hessii(double p[], double delta, int theta, double delti[],double (*func)(double []),int npar);
   mprojmean=yp;    double hessij(double p[], double **hess, double delti[], int i, int j,double (*func)(double []),int npar);
   yp1=modf((yp2*30.5),&yp);    void lubksb(double **a, int npar, int *indx, double b[]) ;
   jprojmean=yp;    void ludcmp(double **a, int npar, int *indx, double *d) ;
   if(jprojmean==0) jprojmean=1;    double gompertz(double p[]);
   if(mprojmean==0) jprojmean=1;    /* hess=matrix(1,npar,1,npar); */
    
   fprintf(ficresf,"# Estimated date of observed prevalence: %.lf/%.lf/%.lf ",jprojmean,mprojmean,anprojmean);    printf("\nCalculation of the hessian matrix. Wait...\n");
      fprintf(ficlog,"\nCalculation of the hessian matrix. Wait...\n");
   for(cptcov=1;cptcov<=i2;cptcov++){    for (i=1;i<=npar;i++){
     for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){      printf("%d-",i);fflush(stdout);
       k=k+1;      fprintf(ficlog,"%d-",i);fflush(ficlog);
       fprintf(ficresf,"\n#******");     
       for(j=1;j<=cptcoveff;j++) {       hess[i][i]=hessii(p,ftolhess,i,delti,func,npar);
         fprintf(ficresf," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);      
       }      /*  printf(" %f ",p[i]);
       fprintf(ficresf,"******\n");          printf(" %lf %lf %lf",hess[i][i],ftolhess,delti[i]);*/
       fprintf(ficresf,"# StartingAge FinalAge");    }
       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficresf," P.%d",j);    
          for (i=1;i<=npar;i++) {
            for (j=1;j<=npar;j++)  {
       for (cpt=0; cpt<=(anproj2-anproj1);cpt++) {        if (j>i) { 
         fprintf(ficresf,"\n");          printf(".%d-%d",i,j);fflush(stdout);
         fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+cpt);            fprintf(ficlog,".%d-%d",i,j);fflush(ficlog);
           hess[i][j]=hessij(p,hess, delti,i,j,func,npar);
         for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(ageminpar-((int)calagedate %12)/12.); agedeb--){          
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);          hess[j][i]=hess[i][j];    
           nhstepm = nhstepm/hstepm;          /*printf(" %lf ",hess[i][j]);*/
                  }
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      }
           oldm=oldms;savm=savms;    }
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);      printf("\n");
            fprintf(ficlog,"\n");
           for (h=0; h<=nhstepm; h++){  
             if (h==(int) (calagedate+YEARM*cpt)) {    printf("\nInverting the hessian to get the covariance matrix. Wait...\n");
               fprintf(ficresf,"\n %.f %.f ",anproj1+cpt,agedeb+h*hstepm/YEARM*stepm);    fprintf(ficlog,"\nInverting the hessian to get the covariance matrix. Wait...\n");
             }    
             for(j=1; j<=nlstate+ndeath;j++) {    a=matrix(1,npar,1,npar);
               kk1=0.;kk2=0;    y=matrix(1,npar,1,npar);
               for(i=1; i<=nlstate;i++) {                  x=vector(1,npar);
                 if (mobilav==1)    indx=ivector(1,npar);
                   kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];    for (i=1;i<=npar;i++)
                 else {      for (j=1;j<=npar;j++) a[i][j]=hess[i][j];
                   kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];    ludcmp(a,npar,indx,&pd);
                 }  
                    for (j=1;j<=npar;j++) {
               }      for (i=1;i<=npar;i++) x[i]=0;
               if (h==(int)(calagedate+12*cpt)){      x[j]=1;
                 fprintf(ficresf," %.3f", kk1);      lubksb(a,npar,indx,x);
                              for (i=1;i<=npar;i++){ 
               }        matcov[i][j]=x[i];
             }      }
           }    }
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);  
         }    printf("\n#Hessian matrix#\n");
       }    fprintf(ficlog,"\n#Hessian matrix#\n");
     }    for (i=1;i<=npar;i++) { 
   }      for (j=1;j<=npar;j++) { 
                printf("%.6e ",hess[i][j]);
   if (mobilav==1) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);        fprintf(ficlog,"%.6e ",hess[i][j]);
       }
   fclose(ficresf);      printf("\n");
 }      fprintf(ficlog,"\n");
 /************** Forecasting ******************/    }
 populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){  
      /* printf("\n#Covariance matrix#\n"); */
   int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;    /* fprintf(ficlog,"\n#Covariance matrix#\n"); */
   int *popage;    /* for (i=1;i<=npar;i++) {  */
   double calagedate, agelim, kk1, kk2, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;    /*   for (j=1;j<=npar;j++) {  */
   double *popeffectif,*popcount;    /*     printf("%.6e ",matcov[i][j]); */
   double ***p3mat,***tabpop,***tabpopprev;    /*     fprintf(ficlog,"%.6e ",matcov[i][j]); */
   char filerespop[FILENAMELENGTH];    /*   } */
     /*   printf("\n"); */
   tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);    /*   fprintf(ficlog,"\n"); */
   tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);    /* } */
   agelim=AGESUP;  
   calagedate=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM;    /* Recompute Inverse */
      /* for (i=1;i<=npar;i++) */
   prevalence(ageminpar, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);    /*   for (j=1;j<=npar;j++) a[i][j]=matcov[i][j]; */
      /* ludcmp(a,npar,indx,&pd); */
    
   strcpy(filerespop,"pop");    /*  printf("\n#Hessian matrix recomputed#\n"); */
   strcat(filerespop,fileres);  
   if((ficrespop=fopen(filerespop,"w"))==NULL) {    /* for (j=1;j<=npar;j++) { */
     printf("Problem with forecast resultfile: %s\n", filerespop);    /*   for (i=1;i<=npar;i++) x[i]=0; */
     fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop);    /*   x[j]=1; */
   }    /*   lubksb(a,npar,indx,x); */
   printf("Computing forecasting: result on file '%s' \n", filerespop);    /*   for (i=1;i<=npar;i++){  */
   fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop);    /*     y[i][j]=x[i]; */
     /*     printf("%.3e ",y[i][j]); */
   if (cptcoveff==0) ncodemax[cptcoveff]=1;    /*     fprintf(ficlog,"%.3e ",y[i][j]); */
     /*   } */
   if (mobilav==1) {    /*   printf("\n"); */
     mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);    /*   fprintf(ficlog,"\n"); */
     movingaverage(agedeb, fage, ageminpar, mobaverage);    /* } */
   }  
     /* Verifying the inverse matrix */
   stepsize=(int) (stepm+YEARM-1)/YEARM;  #ifdef DEBUGHESS
   if (stepm<=12) stepsize=1;    y=matprod2(y,hess,1,npar,1,npar,1,npar,matcov);
    
   agelim=AGESUP;     printf("\n#Verification: multiplying the matrix of covariance by the Hessian matrix, should be unity:#\n");
       fprintf(ficlog,"\n#Verification: multiplying the matrix of covariance by the Hessian matrix. Should be unity:#\n");
   hstepm=1;  
   hstepm=hstepm/stepm;    for (j=1;j<=npar;j++) {
        for (i=1;i<=npar;i++){ 
   if (popforecast==1) {        printf("%.2f ",y[i][j]);
     if((ficpop=fopen(popfile,"r"))==NULL) {        fprintf(ficlog,"%.2f ",y[i][j]);
       printf("Problem with population file : %s\n",popfile);exit(0);      }
       fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0);      printf("\n");
     }      fprintf(ficlog,"\n");
     popage=ivector(0,AGESUP);    }
     popeffectif=vector(0,AGESUP);  #endif
     popcount=vector(0,AGESUP);  
        free_matrix(a,1,npar,1,npar);
     i=1;      free_matrix(y,1,npar,1,npar);
     while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1;    free_vector(x,1,npar);
        free_ivector(indx,1,npar);
     imx=i;    /* free_matrix(hess,1,npar,1,npar); */
     for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i];  
   }  
   }
   for(cptcov=1;cptcov<=i2;cptcov++){  
    for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){  /*************** hessian matrix ****************/
       k=k+1;  double hessii(double x[], double delta, int theta, double delti[], double (*func)(double []), int npar)
       fprintf(ficrespop,"\n#******");  { /* Around values of x, computes the function func and returns the scales delti and hessian */
       for(j=1;j<=cptcoveff;j++) {    int i;
         fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    int l=1, lmax=20;
       }    double k1,k2, res, fx;
       fprintf(ficrespop,"******\n");    double p2[MAXPARM+1]; /* identical to x */
       fprintf(ficrespop,"# Age");    double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4;
       for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j);    int k=0,kmax=10;
       if (popforecast==1)  fprintf(ficrespop," [Population]");    double l1;
        
       for (cpt=0; cpt<=0;cpt++) {    fx=func(x);
         fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);      for (i=1;i<=npar;i++) p2[i]=x[i];
            for(l=0 ; l <=lmax; l++){  /* Enlarging the zone around the Maximum */
         for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(ageminpar-((int)calagedate %12)/12.); agedeb--){      l1=pow(10,l);
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);      delts=delt;
           nhstepm = nhstepm/hstepm;      for(k=1 ; k <kmax; k=k+1){
                  delt = delta*(l1*k);
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);        p2[theta]=x[theta] +delt;
           oldm=oldms;savm=savms;        k1=func(p2)-fx;   /* Might be negative if too close to the theoretical maximum */
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);          p2[theta]=x[theta]-delt;
                k2=func(p2)-fx;
           for (h=0; h<=nhstepm; h++){        /*res= (k1-2.0*fx+k2)/delt/delt; */
             if (h==(int) (calagedate+YEARM*cpt)) {        res= (k1+k2)/delt/delt/2.; /* Divided by 2 because L and not 2*L */
               fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);        
             }  #ifdef DEBUGHESSII
             for(j=1; j<=nlstate+ndeath;j++) {        printf("%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
               kk1=0.;kk2=0;        fprintf(ficlog,"%d %d k1=%.12e k2=%.12e xk1=%.12e xk2=%.12e delt=%.12e res=%.12e l=%d k=%d,fx=%.12e\n",theta,theta,k1,k2,x[theta]+delt,x[theta]-delt,delt,res, l, k,fx);
               for(i=1; i<=nlstate;i++) {                #endif
                 if (mobilav==1)        /*if(fabs(k1-2.0*fx+k2) <1.e-13){ */
                   kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];        if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)){
                 else {          k=kmax;
                   kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];        }
                 }        else if((k1 >khi/nkhif) || (k2 >khi/nkhif)){ /* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. */
               }          k=kmax; l=lmax*10;
               if (h==(int)(calagedate+12*cpt)){        }
                 tabpop[(int)(agedeb)][j][cptcod]=kk1;        else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){ 
                   /*fprintf(ficrespop," %.3f", kk1);          delts=delt;
                     if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*/        }
               }      } /* End loop k */
             }    }
             for(i=1; i<=nlstate;i++){    delti[theta]=delts;
               kk1=0.;    return res; 
                 for(j=1; j<=nlstate;j++){    
                   kk1= kk1+tabpop[(int)(agedeb)][j][cptcod];  }
                 }  
                   tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedate+12*cpt)*hstepm/YEARM*stepm-1)];  double hessij( double x[], double **hess, double delti[], int thetai,int thetaj,double (*func)(double []),int npar)
             }  {
     int i;
             if (h==(int)(calagedate+12*cpt)) for(j=1; j<=nlstate;j++)    int l=1, lmax=20;
               fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]);    double k1,k2,k3,k4,res,fx;
           }    double p2[MAXPARM+1];
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);    int k, kmax=1;
         }    double v1, v2, cv12, lc1, lc2;
       }  
      int firstime=0;
   /******/    
     fx=func(x);
       for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) {    for (k=1; k<=kmax; k=k+10) {
         fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);        for (i=1;i<=npar;i++) p2[i]=x[i];
         for (agedeb=(fage-((int)calagedate %12/12.)); agedeb>=(ageminpar-((int)calagedate %12)/12.); agedeb--){      p2[thetai]=x[thetai]+delti[thetai]*k;
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm);      p2[thetaj]=x[thetaj]+delti[thetaj]*k;
           nhstepm = nhstepm/hstepm;      k1=func(p2)-fx;
              
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      p2[thetai]=x[thetai]+delti[thetai]*k;
           oldm=oldms;savm=savms;      p2[thetaj]=x[thetaj]-delti[thetaj]*k;
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);        k2=func(p2)-fx;
           for (h=0; h<=nhstepm; h++){    
             if (h==(int) (calagedate+YEARM*cpt)) {      p2[thetai]=x[thetai]-delti[thetai]*k;
               fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);      p2[thetaj]=x[thetaj]+delti[thetaj]*k;
             }      k3=func(p2)-fx;
             for(j=1; j<=nlstate+ndeath;j++) {    
               kk1=0.;kk2=0;      p2[thetai]=x[thetai]-delti[thetai]*k;
               for(i=1; i<=nlstate;i++) {                    p2[thetaj]=x[thetaj]-delti[thetaj]*k;
                 kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];          k4=func(p2)-fx;
               }      res=(k1-k2-k3+k4)/4.0/delti[thetai]/k/delti[thetaj]/k/2.; /* Because of L not 2*L */
               if (h==(int)(calagedate+12*cpt)) fprintf(ficresf," %15.2f", kk1);      if(k1*k2*k3*k4 <0.){
             }        firstime=1;
           }        kmax=kmax+10;
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      }
         }      if(kmax >=10 || firstime ==1){
       }        printf("Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; increase ftol=%.2e\n",thetai,thetaj, ftol);
    }        fprintf(ficlog,"Warning: directions %d-%d, you are not estimating the Hessian at the exact maximum likelihood; increase ftol=%.2e\n",thetai,thetaj, ftol);
   }        printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
          fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti*k=%.12e deltj*k=%.12e, xi-de*k=%.12e xj-de*k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
   if (mobilav==1) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);      }
   #ifdef DEBUGHESSIJ
   if (popforecast==1) {      v1=hess[thetai][thetai];
     free_ivector(popage,0,AGESUP);      v2=hess[thetaj][thetaj];
     free_vector(popeffectif,0,AGESUP);      cv12=res;
     free_vector(popcount,0,AGESUP);      /* Computing eigen value of Hessian matrix */
   }      lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
   free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);      lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
   free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);      if ((lc2 <0) || (lc1 <0) ){
   fclose(ficrespop);        printf("Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
 }        fprintf(ficlog, "Warning: sub Hessian matrix '%d%d' does not have positive eigen values \n",thetai,thetaj);
         printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
 /***********************************************/        fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4);
 /**************** Main Program *****************/      }
 /***********************************************/  #endif
     }
 int main(int argc, char *argv[])    return res;
 {  }
   
   int i,j, k, n=MAXN,iter,m,size,cptcode, cptcod;      /* Not done yet: Was supposed to fix if not exactly at the maximum */
   double agedeb, agefin,hf;  /* double hessij( double x[], double delti[], int thetai,int thetaj,double (*func)(double []),int npar) */
   double ageminpar=1.e20,agemin=1.e20, agemaxpar=-1.e20, agemax=-1.e20;  /* { */
   /*   int i; */
   double fret;  /*   int l=1, lmax=20; */
   double **xi,tmp,delta;  /*   double k1,k2,k3,k4,res,fx; */
   /*   double p2[MAXPARM+1]; */
   double dum; /* Dummy variable */  /*   double delt=0.0001, delts, nkhi=10.,nkhif=1., khi=1.e-4; */
   double ***p3mat;  /*   int k=0,kmax=10; */
   int *indx;  /*   double l1; */
   char line[MAXLINE], linepar[MAXLINE];    
   char path[80],pathc[80],pathcd[80],pathtot[80],model[80];  /*   fx=func(x); */
   int firstobs=1, lastobs=10;  /*   for(l=0 ; l <=lmax; l++){  /\* Enlarging the zone around the Maximum *\/ */
   int sdeb, sfin; /* Status at beginning and end */  /*     l1=pow(10,l); */
   int c,  h , cpt,l;  /*     delts=delt; */
   int ju,jl, mi;  /*     for(k=1 ; k <kmax; k=k+1){ */
   int i1,j1, k1,k2,k3,jk,aa,bb, stepsize, ij;  /*       delt = delti*(l1*k); */
   int jnais,jdc,jint4,jint1,jint2,jint3,**outcome,**adl,*tab;  /*       for (i=1;i<=npar;i++) p2[i]=x[i]; */
   int mobilav=0,popforecast=0;  /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
   int hstepm, nhstepm;  /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
   double jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,jpyram, mpyram,anpyram,jpyram1, mpyram1,anpyram1, calagedate;  /*       k1=func(p2)-fx; */
         
   double bage, fage, age, agelim, agebase;  /*       p2[thetai]=x[thetai]+delti[thetai]/k; */
   double ftolpl=FTOL;  /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
   double **prlim;  /*       k2=func(p2)-fx; */
   double *severity;        
   double ***param; /* Matrix of parameters */  /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
   double  *p;  /*       p2[thetaj]=x[thetaj]+delti[thetaj]/k; */
   double **matcov; /* Matrix of covariance */  /*       k3=func(p2)-fx; */
   double ***delti3; /* Scale */        
   double *delti; /* Scale */  /*       p2[thetai]=x[thetai]-delti[thetai]/k; */
   double ***eij, ***vareij;  /*       p2[thetaj]=x[thetaj]-delti[thetaj]/k; */
   double **varpl; /* Variances of prevalence limits by age */  /*       k4=func(p2)-fx; */
   double *epj, vepp;  /*       res=(k1-k2-k3+k4)/4.0/delti[thetai]*k/delti[thetaj]*k/2.; /\* Because of L not 2*L *\/ */
   double kk1, kk2;  /* #ifdef DEBUGHESSIJ */
   double dateprev1, dateprev2,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2;  /*       printf("%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
    /*       fprintf(ficlog,"%d %d k=%d, k1=%.12e k2=%.12e k3=%.12e k4=%.12e delti/k=%.12e deltj/k=%.12e, xi-de/k=%.12e xj-de/k=%.12e  res=%.12e k1234=%.12e,k1-2=%.12e,k3-4=%.12e\n",thetai,thetaj,k,k1,k2,k3,k4,delti[thetai]/k,delti[thetaj]/k,x[thetai]-delti[thetai]/k,x[thetaj]-delti[thetaj]/k, res,k1-k2-k3+k4,k1-k2,k3-k4); */
   /* #endif */
   char *alph[]={"a","a","b","c","d","e"}, str[4];  /*       if((k1 <khi/nkhi/2.) || (k2 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)|| (k4 <khi/nkhi/2.)){ */
   /*      k=kmax; */
   /*       } */
   char z[1]="c", occ;  /*       else if((k1 >khi/nkhif) || (k2 >khi/nkhif) || (k4 >khi/nkhif) || (k4 >khi/nkhif)){ /\* Keeps lastvalue before 3.84/2 KHI2 5% 1d.f. *\/ */
 #include <sys/time.h>  /*      k=kmax; l=lmax*10; */
 #include <time.h>  /*       } */
   char stra[80], strb[80], strc[80], strd[80],stre[80],modelsav[80];  /*       else if((k1 >khi/nkhi) || (k2 >khi/nkhi)){  */
    /*      delts=delt; */
   /* long total_usecs;  /*       } */
   struct timeval start_time, end_time;  /*     } /\* End loop k *\/ */
    /*   } */
   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */  /*   delti[theta]=delts; */
   getcwd(pathcd, size);  /*   return res;  */
   /* } */
   printf("\n%s",version);  
   if(argc <=1){  
     printf("\nEnter the parameter file name: ");  /************** Inverse of matrix **************/
     scanf("%s",pathtot);  void ludcmp(double **a, int n, int *indx, double *d) 
   }  { 
   else{    int i,imax,j,k; 
     strcpy(pathtot,argv[1]);    double big,dum,sum,temp; 
   }    double *vv; 
   /*if(getcwd(pathcd, 80)!= NULL)printf ("Error pathcd\n");*/   
   /*cygwin_split_path(pathtot,path,optionfile);    vv=vector(1,n); 
     printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/    *d=1.0; 
   /* cutv(path,optionfile,pathtot,'\\');*/    for (i=1;i<=n;i++) { 
       big=0.0; 
   split(pathtot,path,optionfile,optionfilext,optionfilefiname);      for (j=1;j<=n;j++) 
    printf("pathtot=%s, path=%s, optionfile=%s optionfilext=%s optionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);        if ((temp=fabs(a[i][j])) > big) big=temp; 
   chdir(path);      if (big == 0.0) nrerror("Singular matrix in routine ludcmp"); 
   replace(pathc,path);      vv[i]=1.0/big; 
     } 
 /*-------- arguments in the command line --------*/    for (j=1;j<=n;j++) { 
       for (i=1;i<j;i++) { 
   /* Log file */        sum=a[i][j]; 
   strcat(filelog, optionfilefiname);        for (k=1;k<i;k++) sum -= a[i][k]*a[k][j]; 
   strcat(filelog,".log");    /* */        a[i][j]=sum; 
   if((ficlog=fopen(filelog,"w"))==NULL)    {      } 
     printf("Problem with logfile %s\n",filelog);      big=0.0; 
     goto end;      for (i=j;i<=n;i++) { 
   }        sum=a[i][j]; 
   fprintf(ficlog,"Log filename:%s\n",filelog);        for (k=1;k<j;k++) 
   fprintf(ficlog,"\n%s",version);          sum -= a[i][k]*a[k][j]; 
   fprintf(ficlog,"\nEnter the parameter file name: ");        a[i][j]=sum; 
   fprintf(ficlog,"pathtot=%s, path=%s, optionfile=%s optionfilext=%s optionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);        if ( (dum=vv[i]*fabs(sum)) >= big) { 
   fflush(ficlog);          big=dum; 
           imax=i; 
   /* */        } 
   strcpy(fileres,"r");      } 
   strcat(fileres, optionfilefiname);      if (j != imax) { 
   strcat(fileres,".txt");    /* Other files have txt extension */        for (k=1;k<=n;k++) { 
           dum=a[imax][k]; 
   /*---------arguments file --------*/          a[imax][k]=a[j][k]; 
           a[j][k]=dum; 
   if((ficpar=fopen(optionfile,"r"))==NULL)    {        } 
     printf("Problem with optionfile %s\n",optionfile);        *d = -(*d); 
     fprintf(ficlog,"Problem with optionfile %s\n",optionfile);        vv[imax]=vv[j]; 
     goto end;      } 
   }      indx[j]=imax; 
       if (a[j][j] == 0.0) a[j][j]=TINY; 
   strcpy(filereso,"o");      if (j != n) { 
   strcat(filereso,fileres);        dum=1.0/(a[j][j]); 
   if((ficparo=fopen(filereso,"w"))==NULL) {        for (i=j+1;i<=n;i++) a[i][j] *= dum; 
     printf("Problem with Output resultfile: %s\n", filereso);      } 
     fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);    } 
     goto end;    free_vector(vv,1,n);  /* Doesn't work */
   }  ;
   } 
   /* Reads comments: lines beginning with '#' */  
   while((c=getc(ficpar))=='#' && c!= EOF){  void lubksb(double **a, int n, int *indx, double b[]) 
     ungetc(c,ficpar);  { 
     fgets(line, MAXLINE, ficpar);    int i,ii=0,ip,j; 
     puts(line);    double sum; 
     fputs(line,ficparo);   
   }    for (i=1;i<=n;i++) { 
   ungetc(c,ficpar);      ip=indx[i]; 
       sum=b[ip]; 
   fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model);      b[ip]=b[i]; 
   printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model);      if (ii) 
   fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);        for (j=ii;j<=i-1;j++) sum -= a[i][j]*b[j]; 
 while((c=getc(ficpar))=='#' && c!= EOF){      else if (sum) ii=i; 
     ungetc(c,ficpar);      b[i]=sum; 
     fgets(line, MAXLINE, ficpar);    } 
     puts(line);    for (i=n;i>=1;i--) { 
     fputs(line,ficparo);      sum=b[i]; 
   }      for (j=i+1;j<=n;j++) sum -= a[i][j]*b[j]; 
   ungetc(c,ficpar);      b[i]=sum/a[i][i]; 
      } 
      } 
   covar=matrix(0,NCOVMAX,1,n);  
   cptcovn=0;  void pstamp(FILE *fichier)
   if (strlen(model)>1) cptcovn=nbocc(model,'+')+1;  {
     fprintf(fichier,"# %s.%s\n#IMaCh version %s, %s\n#%s\n# %s", optionfilefiname,optionfilext,version,copyright, fullversion, strstart);
   ncovmodel=2+cptcovn;  }
   nvar=ncovmodel-1; /* Suppressing age as a basic covariate */  
    /************ Frequencies ********************/
   /* Read guess parameters */  void  freqsummary(char fileres[], int iagemin, int iagemax, int **s, double **agev, int nlstate, int imx, int *Tvaraff, int **nbcode, int *ncodemax,double **mint,double **anint, char strstart[])
   /* Reads comments: lines beginning with '#' */  {  /* Some frequencies */
   while((c=getc(ficpar))=='#' && c!= EOF){    
     ungetc(c,ficpar);    int i, m, jk, j1, bool, z1,j;
     fgets(line, MAXLINE, ficpar);    int first;
     puts(line);    double ***freq; /* Frequencies */
     fputs(line,ficparo);    double *pp, **prop;
   }    double pos,posprop, k2, dateintsum=0,k2cpt=0;
   ungetc(c,ficpar);    char fileresp[FILENAMELENGTH];
      
   param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);    pp=vector(1,nlstate);
     for(i=1; i <=nlstate; i++)    prop=matrix(1,nlstate,iagemin,iagemax+3);
     for(j=1; j <=nlstate+ndeath-1; j++){    strcpy(fileresp,"P_");
       fscanf(ficpar,"%1d%1d",&i1,&j1);    strcat(fileresp,fileresu);
       fprintf(ficparo,"%1d%1d",i1,j1);    if((ficresp=fopen(fileresp,"w"))==NULL) {
       if(mle==1)      printf("Problem with prevalence resultfile: %s\n", fileresp);
         printf("%1d%1d",i,j);      fprintf(ficlog,"Problem with prevalence resultfile: %s\n", fileresp);
       fprintf(ficlog,"%1d%1d",i,j);      exit(0);
       for(k=1; k<=ncovmodel;k++){    }
         fscanf(ficpar," %lf",&param[i][j][k]);    freq= ma3x(-5,nlstate+ndeath,-5,nlstate+ndeath,iagemin,iagemax+3);
         if(mle==1){    j1=0;
           printf(" %lf",param[i][j][k]);    
           fprintf(ficlog," %lf",param[i][j][k]);    j=cptcoveff;
         }    if (cptcovn<1) {j=1;ncodemax[1]=1;}
         else  
           fprintf(ficlog," %lf",param[i][j][k]);    first=1;
         fprintf(ficparo," %lf",param[i][j][k]);  
       }    /* for(k1=1; k1<=j ; k1++){ */  /* Loop on covariates */
       fscanf(ficpar,"\n");    /*  for(i1=1; i1<=ncodemax[k1];i1++){ */ /* Now it is 2 */
       if(mle==1)    /*    j1++; */
         printf("\n");    for (j1 = 1; j1 <= (int) pow(2,cptcoveff); j1++){
       fprintf(ficlog,"\n");        /*printf("cptcoveff=%d Tvaraff=%d", cptcoveff,Tvaraff[1]);
       fprintf(ficparo,"\n");          scanf("%d", i);*/
     }        for (i=-5; i<=nlstate+ndeath; i++)  
            for (jk=-5; jk<=nlstate+ndeath; jk++)  
     npar= (nlstate+ndeath-1)*nlstate*ncovmodel;            for(m=iagemin; m <= iagemax+3; m++)
               freq[i][jk][m]=0;
   p=param[1][1];        
          for (i=1; i<=nlstate; i++)  
   /* Reads comments: lines beginning with '#' */          for(m=iagemin; m <= iagemax+3; m++)
   while((c=getc(ficpar))=='#' && c!= EOF){            prop[i][m]=0;
     ungetc(c,ficpar);        
     fgets(line, MAXLINE, ficpar);        dateintsum=0;
     puts(line);        k2cpt=0;
     fputs(line,ficparo);        for (i=1; i<=imx; i++) {
   }          bool=1;
   ungetc(c,ficpar);          if (cptcovn>0) { /* Filter is here: Must be looked at for model=V1+V2+V3+V4 */
             for (z1=1; z1<=cptcoveff; z1++)       
   delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]){
   delti=vector(1,npar); /* Scale of each paramater (output from hesscov) */                  /* Tests if the value of each of the covariates of i is equal to filter j1 */
   for(i=1; i <=nlstate; i++){                bool=0;
     for(j=1; j <=nlstate+ndeath-1; j++){                /* printf("bool=%d i=%d, z1=%d, Tvaraff[%d]=%d, covar[Tvarff][%d]=%2f, codtabm(%d,%d)=%d, nbcode[Tvaraff][codtabm(%d,%d)=%d, j1=%d\n", 
       fscanf(ficpar,"%1d%1d",&i1,&j1);                  bool,i,z1, z1, Tvaraff[z1],i,covar[Tvaraff[z1]][i],j1,z1,codtabm(j1,z1),
       printf("%1d%1d",i,j);                  j1,z1,nbcode[Tvaraff[z1]][codtabm(j1,z1)],j1);*/
       fprintf(ficparo,"%1d%1d",i1,j1);                /* For j1=7 in V1+V2+V3+V4 = 0 1 1 0 and codtabm(7,3)=1 and nbcde[3][?]=1*/
       for(k=1; k<=ncovmodel;k++){              } 
         fscanf(ficpar,"%le",&delti3[i][j][k]);          } /* cptcovn > 0 */
         printf(" %le",delti3[i][j][k]);   
         fprintf(ficparo," %le",delti3[i][j][k]);          if (bool==1){
       }            for(m=firstpass; m<=lastpass; m++){
       fscanf(ficpar,"\n");              k2=anint[m][i]+(mint[m][i]/12.);
       printf("\n");              /*if ((k2>=dateprev1) && (k2<=dateprev2)) {*/
       fprintf(ficparo,"\n");                if(agev[m][i]==0) agev[m][i]=iagemax+1;
     }                if(agev[m][i]==1) agev[m][i]=iagemax+2;
   }                if (s[m][i]>0 && s[m][i]<=nlstate) prop[s[m][i]][(int)agev[m][i]] += weight[i];
   delti=delti3[1][1];                if (m<lastpass) {
                    freq[s[m][i]][s[m+1][i]][(int)agev[m][i]] += weight[i];
   /* Reads comments: lines beginning with '#' */                  freq[s[m][i]][s[m+1][i]][iagemax+3] += weight[i];
   while((c=getc(ficpar))=='#' && c!= EOF){                }
     ungetc(c,ficpar);                
     fgets(line, MAXLINE, ficpar);                if ((agev[m][i]>1) && (agev[m][i]< (iagemax+3)) && (anint[m][i]!=9999) && (mint[m][i]!=99)) {
     puts(line);                  dateintsum=dateintsum+k2;
     fputs(line,ficparo);                  k2cpt++;
   }                  /* printf("i=%ld dateintmean = %lf dateintsum=%lf k2cpt=%lf k2=%lf\n",i, dateintsum/k2cpt, dateintsum,k2cpt, k2); */
   ungetc(c,ficpar);                }
                  /*}*/
   matcov=matrix(1,npar,1,npar);            } /* end m */
   for(i=1; i <=npar; i++){          } /* end bool */
     fscanf(ficpar,"%s",&str);        } /* end i = 1 to imx */
     if(mle==1)         
       printf("%s",str);        /*      fprintf(ficresp, "#Count between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);*/
     fprintf(ficlog,"%s",str);        pstamp(ficresp);
     fprintf(ficparo,"%s",str);        if  (cptcovn>0) {
     for(j=1; j <=i; j++){          fprintf(ficresp, "\n#********** Variable "); 
       fscanf(ficpar," %le",&matcov[i][j]);          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresp, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
       if(mle==1){          fprintf(ficresp, "**********\n#");
         printf(" %.5le",matcov[i][j]);          fprintf(ficlog, "\n#********** Variable "); 
         fprintf(ficlog," %.5le",matcov[i][j]);          for (z1=1; z1<=cptcoveff; z1++) fprintf(ficlog, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
       }          fprintf(ficlog, "**********\n#");
       else        }
         fprintf(ficlog," %.5le",matcov[i][j]);        for(i=1; i<=nlstate;i++) 
       fprintf(ficparo," %.5le",matcov[i][j]);          fprintf(ficresp, " Age Prev(%d) N(%d) N",i,i);
     }        fprintf(ficresp, "\n");
     fscanf(ficpar,"\n");        
     if(mle==1)        for(i=iagemin; i <= iagemax+3; i++){
       printf("\n");          if(i==iagemax+3){
     fprintf(ficlog,"\n");            fprintf(ficlog,"Total");
     fprintf(ficparo,"\n");          }else{
   }            if(first==1){
   for(i=1; i <=npar; i++)              first=0;
     for(j=i+1;j<=npar;j++)              printf("See log file for details...\n");
       matcov[i][j]=matcov[j][i];            }
                fprintf(ficlog,"Age %d", i);
   if(mle==1)          }
     printf("\n");          for(jk=1; jk <=nlstate ; jk++){
   fprintf(ficlog,"\n");            for(m=-1, pp[jk]=0; m <=nlstate+ndeath ; m++)
               pp[jk] += freq[jk][m][i]; 
           }
     /*-------- Rewriting paramater file ----------*/          for(jk=1; jk <=nlstate ; jk++){
      strcpy(rfileres,"r");    /* "Rparameterfile */            for(m=-1, pos=0; m <=0 ; m++)
      strcat(rfileres,optionfilefiname);    /* Parameter file first name*/              pos += freq[jk][m][i];
      strcat(rfileres,".");    /* */            if(pp[jk]>=1.e-10){
      strcat(rfileres,optionfilext);    /* Other files have txt extension */              if(first==1){
     if((ficres =fopen(rfileres,"w"))==NULL) {                printf(" %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
       printf("Problem writing new parameter file: %s\n", fileres);goto end;              }
       fprintf(ficlog,"Problem writing new parameter file: %s\n", fileres);goto end;              fprintf(ficlog," %d.=%.0f loss[%d]=%.1f%%",jk,pp[jk],jk,100*pos/pp[jk]);
     }            }else{
     fprintf(ficres,"#%s\n",version);              if(first==1)
                    printf(" %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
     /*-------- data file ----------*/              fprintf(ficlog," %d.=%.0f loss[%d]=NaNQ%%",jk,pp[jk],jk);
     if((fic=fopen(datafile,"r"))==NULL)    {            }
       printf("Problem with datafile: %s\n", datafile);goto end;          }
       fprintf(ficlog,"Problem with datafile: %s\n", datafile);goto end;  
     }          for(jk=1; jk <=nlstate ; jk++){
             for(m=0, pp[jk]=0; m <=nlstate+ndeath; m++)
     n= lastobs;              pp[jk] += freq[jk][m][i];
     severity = vector(1,maxwav);          }       
     outcome=imatrix(1,maxwav+1,1,n);          for(jk=1,pos=0,posprop=0; jk <=nlstate ; jk++){
     num=ivector(1,n);            pos += pp[jk];
     moisnais=vector(1,n);            posprop += prop[jk][i];
     annais=vector(1,n);          }
     moisdc=vector(1,n);          for(jk=1; jk <=nlstate ; jk++){
     andc=vector(1,n);            if(pos>=1.e-5){
     agedc=vector(1,n);              if(first==1)
     cod=ivector(1,n);                printf(" %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
     weight=vector(1,n);              fprintf(ficlog," %d.=%.0f prev[%d]=%.1f%%",jk,pp[jk],jk,100*pp[jk]/pos);
     for(i=1;i<=n;i++) weight[i]=1.0; /* Equal weights, 1 by default */            }else{
     mint=matrix(1,maxwav,1,n);              if(first==1)
     anint=matrix(1,maxwav,1,n);                printf(" %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
     s=imatrix(1,maxwav+1,1,n);              fprintf(ficlog," %d.=%.0f prev[%d]=NaNQ%%",jk,pp[jk],jk);
     adl=imatrix(1,maxwav+1,1,n);                }
     tab=ivector(1,NCOVMAX);            if( i <= iagemax){
     ncodemax=ivector(1,8);              if(pos>=1.e-5){
                 fprintf(ficresp," %d %.5f %.0f %.0f",i,prop[jk][i]/posprop, prop[jk][i],posprop);
     i=1;                /*probs[i][jk][j1]= pp[jk]/pos;*/
     while (fgets(line, MAXLINE, fic) != NULL)    {                /*printf("\ni=%d jk=%d j1=%d %.5f %.0f %.0f %f",i,jk,j1,pp[jk]/pos, pp[jk],pos,probs[i][jk][j1]);*/
       if ((i >= firstobs) && (i <=lastobs)) {              }
                      else
         for (j=maxwav;j>=1;j--){                fprintf(ficresp," %d NaNq %.0f %.0f",i,prop[jk][i],posprop);
           cutv(stra, strb,line,' '); s[j][i]=atoi(strb);            }
           strcpy(line,stra);          }
           cutv(stra, strb,line,'/'); anint[j][i]=(double)(atoi(strb)); strcpy(line,stra);          
           cutv(stra, strb,line,' '); mint[j][i]=(double)(atoi(strb)); strcpy(line,stra);          for(jk=-1; jk <=nlstate+ndeath; jk++)
         }            for(m=-1; m <=nlstate+ndeath; m++)
                      if(freq[jk][m][i] !=0 ) {
         cutv(stra, strb,line,'/'); andc[i]=(double)(atoi(strb)); strcpy(line,stra);              if(first==1)
         cutv(stra, strb,line,' '); moisdc[i]=(double)(atoi(strb)); strcpy(line,stra);                printf(" %d%d=%.0f",jk,m,freq[jk][m][i]);
                 fprintf(ficlog," %d%d=%.0f",jk,m,freq[jk][m][i]);
         cutv(stra, strb,line,'/'); annais[i]=(double)(atoi(strb)); strcpy(line,stra);              }
         cutv(stra, strb,line,' '); moisnais[i]=(double)(atoi(strb)); strcpy(line,stra);          if(i <= iagemax)
             fprintf(ficresp,"\n");
         cutv(stra, strb,line,' '); weight[i]=(double)(atoi(strb)); strcpy(line,stra);          if(first==1)
         for (j=ncovcol;j>=1;j--){            printf("Others in log...\n");
           cutv(stra, strb,line,' '); covar[j][i]=(double)(atoi(strb)); strcpy(line,stra);          fprintf(ficlog,"\n");
         }        } /* end loop i */
         num[i]=atol(stra);        /*}*/
            } /* end j1 */
         /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){    dateintmean=dateintsum/k2cpt; 
           printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/   
     fclose(ficresp);
         i=i+1;    free_ma3x(freq,-5,nlstate+ndeath,-5,nlstate+ndeath, iagemin, iagemax+3);
       }    free_vector(pp,1,nlstate);
     }    free_matrix(prop,1,nlstate,iagemin, iagemax+3);
     /* printf("ii=%d", ij);    /* End of Freq */
        scanf("%d",i);*/  }
   imx=i-1; /* Number of individuals */  
   /************ Prevalence ********************/
   /* for (i=1; i<=imx; i++){  void prevalence(double ***probs, double agemin, double agemax, int **s, double **agev, int nlstate, int imx, int *Tvar, int **nbcode, int *ncodemax,double **mint,double **anint, double dateprev1,double dateprev2, int firstpass, int lastpass)
     if ((s[1][i]==3) && (s[2][i]==2)) s[2][i]=3;  {  
     if ((s[2][i]==3) && (s[3][i]==2)) s[3][i]=3;    /* Compute observed prevalence between dateprev1 and dateprev2 by counting the number of people
     if ((s[3][i]==3) && (s[4][i]==2)) s[4][i]=3;       in each health status at the date of interview (if between dateprev1 and dateprev2).
     }*/       We still use firstpass and lastpass as another selection.
    /*  for (i=1; i<=imx; i++){    */
      if (s[4][i]==9)  s[4][i]=-1;   
      printf("%d %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]), (weight[i]), (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i]));}*/    int i, m, jk, j1, bool, z1,j;
    
      double **prop;
   /* Calculation of the number of parameter from char model*/    double posprop; 
   Tvar=ivector(1,15); /* stores the number n of the covariates in Vm+Vn at 1 and m at 2 */    double  y2; /* in fractional years */
   Tprod=ivector(1,15);    int iagemin, iagemax;
   Tvaraff=ivector(1,15);    int first; /** to stop verbosity which is redirected to log file */
   Tvard=imatrix(1,15,1,2);  
   Tage=ivector(1,15);          iagemin= (int) agemin;
        iagemax= (int) agemax;
   if (strlen(model) >1){    /*pp=vector(1,nlstate);*/
     j=0, j1=0, k1=1, k2=1;    prop=matrix(1,nlstate,iagemin,iagemax+3); 
     j=nbocc(model,'+');    /*  freq=ma3x(-1,nlstate+ndeath,-1,nlstate+ndeath,iagemin,iagemax+3);*/
     j1=nbocc(model,'*');    j1=0;
     cptcovn=j+1;    
     cptcovprod=j1;    /*j=cptcoveff;*/
        if (cptcovn<1) {j=1;ncodemax[1]=1;}
     strcpy(modelsav,model);    
     if ((strcmp(model,"age")==0) || (strcmp(model,"age*age")==0)){    first=1;
       printf("Error. Non available option model=%s ",model);    for(j1=1; j1<= (int) pow(2,cptcoveff);j1++){
       fprintf(ficlog,"Error. Non available option model=%s ",model);      /*for(i1=1; i1<=ncodemax[k1];i1++){
       goto end;        j1++;*/
     }        
            for (i=1; i<=nlstate; i++)  
     for(i=(j+1); i>=1;i--){          for(m=iagemin; m <= iagemax+3; m++)
       cutv(stra,strb,modelsav,'+'); /* keeps in strb after the last + */            prop[i][m]=0.0;
       if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyze it */       
       /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/        for (i=1; i<=imx; i++) { /* Each individual */
       /*scanf("%d",i);*/          bool=1;
       if (strchr(strb,'*')) {  /* Model includes a product */          if  (cptcovn>0) {
         cutv(strd,strc,strb,'*'); /* strd*strc  Vm*Vn (if not *age)*/            for (z1=1; z1<=cptcoveff; z1++) 
         if (strcmp(strc,"age")==0) { /* Vn*age */              if (covar[Tvaraff[z1]][i]!= nbcode[Tvaraff[z1]][codtabm(j1,z1)]) 
           cptcovprod--;                bool=0;
           cutv(strb,stre,strd,'V');          } 
           Tvar[i]=atoi(stre); /* computes n in Vn and stores in Tvar*/          if (bool==1) { 
           cptcovage++;            for(m=firstpass; m<=lastpass; m++){/* Other selection (we can limit to certain interviews*/
             Tage[cptcovage]=i;              y2=anint[m][i]+(mint[m][i]/12.); /* Fractional date in year */
             /*printf("stre=%s ", stre);*/              if ((y2>=dateprev1) && (y2<=dateprev2)) { /* Here is the main selection (fractional years) */
         }                if(agev[m][i]==0) agev[m][i]=iagemax+1;
         else if (strcmp(strd,"age")==0) { /* or age*Vn */                if(agev[m][i]==1) agev[m][i]=iagemax+2;
           cptcovprod--;                if((int)agev[m][i] <iagemin || (int)agev[m][i] >iagemax+3) printf("Error on individual =%d agev[m][i]=%f m=%d\n",i, agev[m][i],m); 
           cutv(strb,stre,strc,'V');                if (s[m][i]>0 && s[m][i]<=nlstate) { 
           Tvar[i]=atoi(stre);                  /*if(i>4620) printf(" i=%d m=%d s[m][i]=%d (int)agev[m][i]=%d weight[i]=%f prop=%f\n",i,m,s[m][i],(int)agev[m][m],weight[i],prop[s[m][i]][(int)agev[m][i]]);*/
           cptcovage++;                  prop[s[m][i]][(int)agev[m][i]] += weight[i];
           Tage[cptcovage]=i;                  prop[s[m][i]][iagemax+3] += weight[i]; 
         }                } 
         else {  /* Age is not in the model */              }
           cutv(strb,stre,strc,'V'); /* strc= Vn, stre is n*/            } /* end selection of waves */
           Tvar[i]=ncovcol+k1;          }
           cutv(strb,strc,strd,'V'); /* strd was Vm, strc is m */        }
           Tprod[k1]=i;        for(i=iagemin; i <= iagemax+3; i++){  
           Tvard[k1][1]=atoi(strc); /* m*/          for(jk=1,posprop=0; jk <=nlstate ; jk++) { 
           Tvard[k1][2]=atoi(stre); /* n */            posprop += prop[jk][i]; 
           Tvar[cptcovn+k2]=Tvard[k1][1];          } 
           Tvar[cptcovn+k2+1]=Tvard[k1][2];          
           for (k=1; k<=lastobs;k++)          for(jk=1; jk <=nlstate ; jk++){     
             covar[ncovcol+k1][k]=covar[atoi(stre)][k]*covar[atoi(strc)][k];            if( i <=  iagemax){ 
           k1++;              if(posprop>=1.e-5){ 
           k2=k2+2;                probs[i][jk][j1]= prop[jk][i]/posprop;
         }              } else{
       }                if(first==1){
       else { /* no more sum */                  first=0;
         /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/                  printf("Warning Observed prevalence probs[%d][%d][%d]=%lf because of lack of cases\nSee others on log file...\n",jk,i,j1,probs[i][jk][j1]);
        /*  scanf("%d",i);*/                }
       cutv(strd,strc,strb,'V');              }
       Tvar[i]=atoi(strc);            } 
       }          }/* end jk */ 
       strcpy(modelsav,stra);          }/* end i */ 
       /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);      /*} *//* end i1 */
         scanf("%d",i);*/    } /* end j1 */
     } /* end of loop + */    
   } /* end model */    /*  free_ma3x(freq,-1,nlstate+ndeath,-1,nlstate+ndeath, iagemin, iagemax+3);*/
      /*free_vector(pp,1,nlstate);*/
   /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);    free_matrix(prop,1,nlstate, iagemin,iagemax+3);
   printf("cptcovprod=%d ", cptcovprod);  }  /* End of prevalence */
   fprintf(ficlog,"cptcovprod=%d ", cptcovprod);  
   scanf("%d ",i);*/  /************* Waves Concatenation ***************/
     fclose(fic);  
   void  concatwav(int wav[], int **dh, int **bh,  int **mw, int **s, double *agedc, double **agev, int  firstpass, int lastpass, int imx, int nlstate, int stepm)
     /*  if(mle==1){*/  {
     if (weightopt != 1) { /* Maximisation without weights*/    /* Concatenates waves: wav[i] is the number of effective (useful waves) of individual i.
       for(i=1;i<=n;i++) weight[i]=1.0;       Death is a valid wave (if date is known).
     }       mw[mi][i] is the mi (mi=1 to wav[i])  effective wave of individual i
     /*-calculation of age at interview from date of interview and age at death -*/       dh[m][i] or dh[mw[mi][i]][i] is the delay between two effective waves m=mw[mi][i]
     agev=matrix(1,maxwav,1,imx);       and mw[mi+1][i]. dh depends on stepm.
        */
     for (i=1; i<=imx; i++) {  
       for(m=2; (m<= maxwav); m++) {    int i, mi, m;
        if ((mint[m][i]== 99) && (s[m][i] <= nlstate)){    /* int j, k=0,jk, ju, jl,jmin=1e+5, jmax=-1;
          anint[m][i]=9999;       double sum=0., jmean=0.;*/
          s[m][i]=-1;    int first;
        }    int j, k=0,jk, ju, jl;
      if(moisdc[i]==99 && andc[i]==9999 & s[m][i]>nlstate) s[m][i]=-1;    double sum=0.;
       }    first=0;
     }    jmin=100000;
     jmax=-1;
     for (i=1; i<=imx; i++)  {    jmean=0.;
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);    for(i=1; i<=imx; i++){
       for(m=1; (m<= maxwav); m++){      mi=0;
         if(s[m][i] >0){      m=firstpass;
           if (s[m][i] >= nlstate+1) {      while(s[m][i] <= nlstate){
             if(agedc[i]>0)        if(s[m][i]>=1 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5)
               if(moisdc[i]!=99 && andc[i]!=9999)          mw[++mi][i]=m;
                 agev[m][i]=agedc[i];        if(m >=lastpass)
             /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/          break;
            else {        else
               if (andc[i]!=9999){          m++;
               printf("Warning negative age at death: %d line:%d\n",num[i],i);      }/* end while */
               fprintf(ficlog,"Warning negative age at death: %d line:%d\n",num[i],i);      if (s[m][i] > nlstate){
               agev[m][i]=-1;        mi++;     /* Death is another wave */
               }        /* if(mi==0)  never been interviewed correctly before death */
             }           /* Only death is a correct wave */
           }        mw[mi][i]=m;
           else if(s[m][i] !=9){ /* Should no more exist */      }
             agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);  
             if(mint[m][i]==99 || anint[m][i]==9999)      wav[i]=mi;
               agev[m][i]=1;      if(mi==0){
             else if(agev[m][i] <agemin){        nbwarn++;
               agemin=agev[m][i];        if(first==0){
               /*printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], agemin);*/          printf("Warning! No valid information for individual %ld line=%d (skipped) and may be others, see log file\n",num[i],i);
             }          first=1;
             else if(agev[m][i] >agemax){        }
               agemax=agev[m][i];        if(first==1){
              /* printf(" anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.0f\n",m,i,anint[m][i], i,annais[i], agemax);*/          fprintf(ficlog,"Warning! No valid information for individual %ld line=%d (skipped)\n",num[i],i);
             }        }
             /*agev[m][i]=anint[m][i]-annais[i];*/      } /* end mi==0 */
             /*   agev[m][i] = age[i]+2*m;*/    } /* End individuals */
           }  
           else { /* =9 */    for(i=1; i<=imx; i++){
             agev[m][i]=1;      for(mi=1; mi<wav[i];mi++){
             s[m][i]=-1;        if (stepm <=0)
           }          dh[mi][i]=1;
         }        else{
         else /*= 0 Unknown */          if (s[mw[mi+1][i]][i] > nlstate) { /* A death */
           agev[m][i]=1;            if (agedc[i] < 2*AGESUP) {
       }              j= rint(agedc[i]*12-agev[mw[mi][i]][i]*12); 
                  if(j==0) j=1;  /* Survives at least one month after exam */
     }              else if(j<0){
     for (i=1; i<=imx; i++)  {                nberr++;
       for(m=1; (m<= maxwav); m++){                printf("Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
         if (s[m][i] > (nlstate+ndeath)) {                j=1; /* Temporary Dangerous patch */
           printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);                  printf("   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
           fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);                  fprintf(ficlog,"Error! Negative delay (%d to death) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
           goto end;                fprintf(ficlog,"   We assumed that the date of interview was correct (and not the date of death) and postponed the death %d month(s) (one stepm) after the interview. You MUST fix the contradiction between dates.\n",stepm);
         }              }
       }              k=k+1;
     }              if (j >= jmax){
                 jmax=j;
 printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, agemin, agemax);                ijmax=i;
  fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, agemin, agemax);              }
               if (j <= jmin){
     free_vector(severity,1,maxwav);                jmin=j;
     free_imatrix(outcome,1,maxwav+1,1,n);                ijmin=i;
     free_vector(moisnais,1,n);              }
     free_vector(annais,1,n);              sum=sum+j;
     /* free_matrix(mint,1,maxwav,1,n);              /*if (j<0) printf("j=%d num=%d \n",j,i);*/
        free_matrix(anint,1,maxwav,1,n);*/              /*    printf("%d %d %d %d\n", s[mw[mi][i]][i] ,s[mw[mi+1][i]][i],j,i);*/
     free_vector(moisdc,1,n);            }
     free_vector(andc,1,n);          }
           else{
                j= rint( (agev[mw[mi+1][i]][i]*12 - agev[mw[mi][i]][i]*12));
     wav=ivector(1,imx);  /*        if (j<0) printf("%d %lf %lf %d %d %d\n", i,agev[mw[mi+1][i]][i], agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]); */
     dh=imatrix(1,lastpass-firstpass+1,1,imx);  
     mw=imatrix(1,lastpass-firstpass+1,1,imx);            k=k+1;
                if (j >= jmax) {
     /* Concatenates waves */              jmax=j;
       concatwav(wav, dh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);              ijmax=i;
             }
             else if (j <= jmin){
       Tcode=ivector(1,100);              jmin=j;
       nbcode=imatrix(0,NCOVMAX,0,NCOVMAX);              ijmin=i;
       ncodemax[1]=1;            }
       if (cptcovn > 0) tricode(Tvar,nbcode,imx);            /*        if (j<10) printf("j=%d jmin=%d num=%d ",j,jmin,i); */
                  /*printf("%d %lf %d %d %d\n", i,agev[mw[mi][i]][i],j,s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);*/
    codtab=imatrix(1,100,1,10);            if(j<0){
    h=0;              nberr++;
    m=pow(2,cptcoveff);              printf("Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
                fprintf(ficlog,"Error! Negative delay (%d) between waves %d and %d of individual %ld at line %d who is aged %.1f with statuses from %d to %d\n ",j,mw[mi][i],mw[mi+1][i],num[i], i,agev[mw[mi][i]][i],s[mw[mi][i]][i] ,s[mw[mi+1][i]][i]);
    for(k=1;k<=cptcoveff; k++){            }
      for(i=1; i <=(m/pow(2,k));i++){            sum=sum+j;
        for(j=1; j <= ncodemax[k]; j++){          }
          for(cpt=1; cpt <=(m/pow(2,cptcoveff+1-k)); cpt++){          jk= j/stepm;
            h++;          jl= j -jk*stepm;
            if (h>m) h=1;codtab[h][k]=j;codtab[h][Tvar[k]]=j;          ju= j -(jk+1)*stepm;
            /*  printf("h=%d k=%d j=%d codtab[h][k]=%d tvar[k]=%d \n",h, k,j,codtab[h][k],Tvar[k]);*/          if(mle <=1){ /* only if we use a the linear-interpoloation pseudo-likelihood */
          }            if(jl==0){
        }              dh[mi][i]=jk;
      }              bh[mi][i]=0;
    }            }else{ /* We want a negative bias in order to only have interpolation ie
    /* printf("codtab[1][2]=%d codtab[2][2]=%d",codtab[1][2],codtab[2][2]);                    * to avoid the price of an extra matrix product in likelihood */
       codtab[1][2]=1;codtab[2][2]=2; */              dh[mi][i]=jk+1;
    /* for(i=1; i <=m ;i++){              bh[mi][i]=ju;
       for(k=1; k <=cptcovn; k++){            }
       printf("i=%d k=%d %d %d ",i,k,codtab[i][k], cptcoveff);          }else{
       }            if(jl <= -ju){
       printf("\n");              dh[mi][i]=jk;
       }              bh[mi][i]=jl;       /* bias is positive if real duration
       scanf("%d",i);*/                                   * is higher than the multiple of stepm and negative otherwise.
                                       */
    /* Calculates basic frequencies. Computes observed prevalence at single age            }
        and prints on file fileres'p'. */            else{
               dh[mi][i]=jk+1;
                  bh[mi][i]=ju;
                }
     pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */            if(dh[mi][i]==0){
     oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */              dh[mi][i]=1; /* At least one step */
     newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */              bh[mi][i]=ju; /* At least one step */
     savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */              /*  printf(" bh=%d ju=%d jl=%d dh=%d jk=%d stepm=%d %d\n",bh[mi][i],ju,jl,dh[mi][i],jk,stepm,i);*/
     oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */            }
                } /* end if mle */
     /* For Powell, parameters are in a vector p[] starting at p[1]        }
        so we point p on param[1][1] so that p[1] maps on param[1][1][1] */      } /* end wave */
     p=param[1][1]; /* *(*(*(param +1)+1)+0) */    }
     jmean=sum/k;
     if(mle==1){    printf("Delay (in months) between two waves Min=%d (for indiviudal %ld) Max=%d (%ld) Mean=%f\n\n ",jmin, num[ijmin], jmax, num[ijmax], jmean);
     mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);    fprintf(ficlog,"Delay (in months) between two waves Min=%d (for indiviudal %d) Max=%d (%d) Mean=%f\n\n ",jmin, ijmin, jmax, ijmax, jmean);
     }   }
      
     /*--------- results files --------------*/  /*********** Tricode ****************************/
     fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model);  void tricode(int *Tvar, int **nbcode, int imx, int *Ndum)
    {
     /**< Uses cptcovn+2*cptcovprod as the number of covariates */
    jk=1;    /*      Tvar[i]=atoi(stre);  find 'n' in Vn and stores in Tvar. If model=V2+V1 Tvar[1]=2 and Tvar[2]=1 
    fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");     * Boring subroutine which should only output nbcode[Tvar[j]][k]
    printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");     * Tvar[5] in V2+V1+V3*age+V2*V4 is 2 (V2)
    fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");     * nbcode[Tvar[j]][1]= 
    for(i=1,jk=1; i <=nlstate; i++){    */
      for(k=1; k <=(nlstate+ndeath); k++){  
        if (k != i)    int ij=1, k=0, j=0, i=0, maxncov=NCOVMAX;
          {    int modmaxcovj=0; /* Modality max of covariates j */
            printf("%d%d ",i,k);    int cptcode=0; /* Modality max of covariates j */
            fprintf(ficlog,"%d%d ",i,k);    int modmincovj=0; /* Modality min of covariates j */
            fprintf(ficres,"%1d%1d ",i,k);  
            for(j=1; j <=ncovmodel; j++){  
              printf("%f ",p[jk]);    cptcoveff=0; 
              fprintf(ficlog,"%f ",p[jk]);   
              fprintf(ficres,"%f ",p[jk]);    for (k=1; k <= maxncov; k++) ncodemax[k]=0; /* Horrible constant again replaced by NCOVMAX */
              jk++;  
            }    /* Loop on covariates without age and products */
            printf("\n");    for (j=1; j<=(cptcovs); j++) { /* From model V1 + V2*age+ V3 + V3*V4 keeps V1 + V3 = 2 only */
            fprintf(ficlog,"\n");      for (k=-1; k < maxncov; k++) Ndum[k]=0;
            fprintf(ficres,"\n");      for (i=1; i<=imx; i++) { /* Loop on individuals: reads the data file to get the maximum value of the 
          }                                 modality of this covariate Vj*/ 
      }        ij=(int)(covar[Tvar[j]][i]); /* ij=0 or 1 or -1. Value of the covariate Tvar[j] for individual i
    }                                      * If product of Vn*Vm, still boolean *:
    if(mle==1){                                      * If it was coded 1, 2, 3, 4 should be splitted into 3 boolean variables
      /* Computing hessian and covariance matrix */                                      * 1 => 0 0 0, 2 => 0 0 1, 3 => 0 1 1, 4=1 0 0   */
      ftolhess=ftol; /* Usually correct */        /* Finds for covariate j, n=Tvar[j] of Vn . ij is the
      hesscov(matcov, p, npar, delti, ftolhess, func);                                        modality of the nth covariate of individual i. */
    }        if (ij > modmaxcovj)
    fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");          modmaxcovj=ij; 
    printf("# Scales (for hessian or gradient estimation)\n");        else if (ij < modmincovj) 
    fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");          modmincovj=ij; 
    for(i=1,jk=1; i <=nlstate; i++){        if ((ij < -1) && (ij > NCOVMAX)){
      for(j=1; j <=nlstate+ndeath; j++){          printf( "Error: minimal is less than -1 or maximal is bigger than %d. Exiting. \n", NCOVMAX );
        if (j!=i) {          exit(1);
          fprintf(ficres,"%1d%1d",i,j);        }else
          printf("%1d%1d",i,j);        Ndum[ij]++; /*counts and stores the occurence of this modality 0, 1, -1*/
          fprintf(ficlog,"%1d%1d",i,j);        /*  If coded 1, 2, 3 , counts the number of 1 Ndum[1], number of 2, Ndum[2], etc */
          for(k=1; k<=ncovmodel;k++){        /*printf("i=%d ij=%d Ndum[ij]=%d imx=%d",i,ij,Ndum[ij],imx);*/
            printf(" %.5e",delti[jk]);        /* getting the maximum value of the modality of the covariate
            fprintf(ficlog," %.5e",delti[jk]);           (should be 0 or 1 now) Tvar[j]. If V=sex and male is coded 0 and
            fprintf(ficres," %.5e",delti[jk]);           female is 1, then modmaxcovj=1.*/
            jk++;      } /* end for loop on individuals i */
          }      printf(" Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", j, Tvar[j], modmincovj, modmaxcovj);
          printf("\n");      fprintf(ficlog," Minimal and maximal values of %d th covariate V%d: min=%d max=%d \n", j, Tvar[j], modmincovj, modmaxcovj);
          fprintf(ficlog,"\n");      cptcode=modmaxcovj;
          fprintf(ficres,"\n");      /* Ndum[0] = frequency of 0 for model-covariate j, Ndum[1] frequency of 1 etc. */
        }     /*for (i=0; i<=cptcode; i++) {*/
      }      for (k=modmincovj;  k<=modmaxcovj; k++) { /* k=-1 ? 0 and 1*//* For each value k of the modality of model-cov j */
    }        printf("Frequencies of covariates %d ie V%d with value %d: %d\n", j, Tvar[j], k, Ndum[k]);
            fprintf(ficlog, "Frequencies of covariates %d ie V%d with value %d: %d\n", j, Tvar[j], k, Ndum[k]);
    k=1;        if( Ndum[k] != 0 ){ /* Counts if nobody answered modality k ie empty modality, we skip it and reorder */
    fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");          if( k != -1){
    if(mle==1)            ncodemax[j]++;  /* ncodemax[j]= Number of modalities of the j th
      printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");                               covariate for which somebody answered excluding 
    fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");                               undefined. Usually 2: 0 and 1. */
    for(i=1;i<=npar;i++){          }
      /*  if (k>nlstate) k=1;          ncodemaxwundef[j]++; /* ncodemax[j]= Number of modalities of the j th
          i1=(i-1)/(ncovmodel*nlstate)+1;                               covariate for which somebody answered including 
          fprintf(ficres,"%s%d%d",alph[k],i1,tab[i]);                               undefined. Usually 3: -1, 0 and 1. */
          printf("%s%d%d",alph[k],i1,tab[i]);*/        }
      fprintf(ficres,"%3d",i);        /* In fact  ncodemax[j]=2 (dichotom. variables only) but it could be more for
      if(mle==1)           historical reasons: 3 if coded 1, 2, 3 and 4 and Ndum[2]=0 */
        printf("%3d",i);      } /* Ndum[-1] number of undefined modalities */
      fprintf(ficlog,"%3d",i);  
      for(j=1; j<=i;j++){      /* j is a covariate, n=Tvar[j] of Vn; Fills nbcode */
        fprintf(ficres," %.5e",matcov[i][j]);      /* For covariate j, modalities could be 1, 2, 3, 4, 5, 6, 7. 
        if(mle==1)         If Ndum[1]=0, Ndum[2]=0, Ndum[3]= 635, Ndum[4]=0, Ndum[5]=0, Ndum[6]=27, Ndum[7]=125;
          printf(" %.5e",matcov[i][j]);         modmincovj=3; modmaxcovj = 7;
        fprintf(ficlog," %.5e",matcov[i][j]);         There are only 3 modalities non empty 3, 6, 7 (or 2 if 27 is too few) : ncodemax[j]=3;
      }         which will be coded 0, 1, 2 which in binary on 2=3-1 digits are 0=00 1=01, 2=10;
      fprintf(ficres,"\n");         defining two dummy variables: variables V1_1 and V1_2.
      if(mle==1)         nbcode[Tvar[j]][ij]=k;
        printf("\n");         nbcode[Tvar[j]][1]=0;
      fprintf(ficlog,"\n");         nbcode[Tvar[j]][2]=1;
      k++;         nbcode[Tvar[j]][3]=2;
    }         To be continued (not working yet).
          */
    while((c=getc(ficpar))=='#' && c!= EOF){      ij=0; /* ij is similar to i but can jump over null modalities */
      ungetc(c,ficpar);      for (i=modmincovj; i<=modmaxcovj; i++) { /* i= 1 to 2 for dichotomous, or from 1 to 3 or from -1 or 0 to 1 currently*/
      fgets(line, MAXLINE, ficpar);          if (Ndum[i] == 0) { /* If nobody responded to this modality k */
      puts(line);            break;
      fputs(line,ficparo);          }
    }          ij++;
    ungetc(c,ficpar);          nbcode[Tvar[j]][ij]=i;  /* stores the original value of modality i in an array nbcode, ij modality from 1 to last non-nul modality.*/
    estepm=0;          cptcode = ij; /* New max modality for covar j */
    fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm);      } /* end of loop on modality i=-1 to 1 or more */
    if (estepm==0 || estepm < stepm) estepm=stepm;        
    if (fage <= 2) {      /*   for (k=0; k<= cptcode; k++) { /\* k=-1 ? k=0 to 1 *\//\* Could be 1 to 4 *\//\* cptcode=modmaxcovj *\/ */
      bage = ageminpar;      /*  /\*recode from 0 *\/ */
      fage = agemaxpar;      /*                               k is a modality. If we have model=V1+V1*sex  */
    }      /*                               then: nbcode[1][1]=0 ; nbcode[1][2]=1; nbcode[2][1]=0 ; nbcode[2][2]=1; */
          /*                            But if some modality were not used, it is recoded from 0 to a newer modmaxcovj=cptcode *\/ */
    fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");      /*  } */
    fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);      /*  /\* cptcode = ij; *\/ /\* New max modality for covar j *\/ */
    fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);      /*  if (ij > ncodemax[j]) { */
          /*    printf( " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]);  */
    while((c=getc(ficpar))=='#' && c!= EOF){      /*    fprintf(ficlog, " Error ij=%d > ncodemax[%d]=%d\n", ij, j, ncodemax[j]); */
      ungetc(c,ficpar);      /*    break; */
      fgets(line, MAXLINE, ficpar);      /*  } */
      puts(line);      /*   }  /\* end of loop on modality k *\/ */
      fputs(line,ficparo);    } /* end of loop on model-covariate j. nbcode[Tvarj][1]=0 and nbcode[Tvarj][2]=1 sets the value of covariate j*/  
    }    
    ungetc(c,ficpar);   for (k=-1; k< maxncov; k++) Ndum[k]=0; 
      
    fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2);    for (i=1; i<=ncovmodel-2-nagesqr; i++) { /* -2, cste and age and eventually age*age */ 
    fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);     /* Listing of all covariables in statement model to see if some covariates appear twice. For example, V1 appears twice in V1+V1*V2.*/ 
    fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);     ij=Tvar[i]; /* Tvar might be -1 if status was unknown */ 
         Ndum[ij]++; /* Might be supersed V1 + V1*age */
    while((c=getc(ficpar))=='#' && c!= EOF){   } 
      ungetc(c,ficpar);  
      fgets(line, MAXLINE, ficpar);   ij=0;
      puts(line);   for (i=0; i<=  maxncov-1; i++) { /* modmaxcovj is unknown here. Only Ndum[2(V2),3(age*V3), 5(V3*V2) 6(V1*V4) */
      fputs(line,ficparo);     /*printf("Ndum[%d]=%d\n",i, Ndum[i]);*/
    }     if((Ndum[i]!=0) && (i<=ncovcol)){
    ungetc(c,ficpar);       ij++;
         /*printf("diff Ndum[%d]=%d\n",i, Ndum[i]);*/
        Tvaraff[ij]=i; /*For printing (unclear) */
    dateprev1=anprev1+mprev1/12.+jprev1/365.;     }else{
    dateprev2=anprev2+mprev2/12.+jprev2/365.;         /* Tvaraff[ij]=0; */
      }
   fscanf(ficpar,"pop_based=%d\n",&popbased);   }
   fprintf(ficparo,"pop_based=%d\n",popbased);     /* ij--; */
   fprintf(ficres,"pop_based=%d\n",popbased);     cptcoveff=ij; /*Number of total covariates*/
    
   while((c=getc(ficpar))=='#' && c!= EOF){  }
     ungetc(c,ficpar);  
     fgets(line, MAXLINE, ficpar);  
     puts(line);  /*********** Health Expectancies ****************/
     fputs(line,ficparo);  
   }  void evsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,char strstart[] )
   ungetc(c,ficpar);  
   {
   fscanf(ficpar,"starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mov_average=%d\n",&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilav);    /* Health expectancies, no variances */
 fprintf(ficparo,"starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mov_average=%d\n",jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilav);    int i, j, nhstepm, hstepm, h, nstepm;
 fprintf(ficres,"starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mov_average=%d\n",jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilav);    int nhstepma, nstepma; /* Decreasing with age */
     double age, agelim, hf;
     double ***p3mat;
 while((c=getc(ficpar))=='#' && c!= EOF){    double eip;
     ungetc(c,ficpar);  
     fgets(line, MAXLINE, ficpar);    pstamp(ficreseij);
     puts(line);    fprintf(ficreseij,"# (a) Life expectancies by health status at initial age and (b) health expectancies by health status at initial age\n");
     fputs(line,ficparo);    fprintf(ficreseij,"# Age");
   }    for(i=1; i<=nlstate;i++){
   ungetc(c,ficpar);      for(j=1; j<=nlstate;j++){
         fprintf(ficreseij," e%1d%1d ",i,j);
   fscanf(ficpar,"popforecast=%d popfile=%s popfiledate=%lf/%lf/%lf last-popfiledate=%lf/%lf/%lf\n",&popforecast,popfile,&jpyram,&mpyram,&anpyram,&jpyram1,&mpyram1,&anpyram1);      }
   fprintf(ficparo,"popforecast=%d popfile=%s popfiledate=%.lf/%.lf/%.lf last-popfiledate=%.lf/%.lf/%.lf\n",popforecast,popfile,jpyram,mpyram,anpyram,jpyram1,mpyram1,anpyram1);      fprintf(ficreseij," e%1d. ",i);
   fprintf(ficres,"popforecast=%d popfile=%s popfiledate=%.lf/%.lf/%.lf last-popfiledate=%.lf/%.lf/%.lf\n",popforecast,popfile,jpyram,mpyram,anpyram,jpyram1,mpyram1,anpyram1);    }
     fprintf(ficreseij,"\n");
  freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2);  
     
 /*------------ gnuplot -------------*/    if(estepm < stepm){
   strcpy(optionfilegnuplot,optionfilefiname);      printf ("Problem %d lower than %d\n",estepm, stepm);
   strcat(optionfilegnuplot,".gp");    }
   if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {    else  hstepm=estepm;   
     printf("Problem with file %s",optionfilegnuplot);    /* We compute the life expectancy from trapezoids spaced every estepm months
   }     * This is mainly to measure the difference between two models: for example
   fclose(ficgp);     * if stepm=24 months pijx are given only every 2 years and by summing them
  printinggnuplot(fileres, ageminpar,agemaxpar,fage, pathc,p);     * we are calculating an estimate of the Life Expectancy assuming a linear 
 /*--------- index.htm --------*/     * progression in between and thus overestimating or underestimating according
      * to the curvature of the survival function. If, for the same date, we 
   strcpy(optionfilehtm,optionfile);     * estimate the model with stepm=1 month, we can keep estepm to 24 months
   strcat(optionfilehtm,".htm");     * to compare the new estimate of Life expectancy with the same linear 
   if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {     * hypothesis. A more precise result, taking into account a more precise
     printf("Problem with %s \n",optionfilehtm), exit(0);     * curvature will be obtained if estepm is as small as stepm. */
   }  
     /* For example we decided to compute the life expectancy with the smallest unit */
   fprintf(fichtm,"<body> <font size=\"2\">%s </font> <hr size=\"2\" color=\"#EC5E5E\"> \n    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
 Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=%s<br>\n       nhstepm is the number of hstepm from age to agelim 
 \n       nstepm is the number of stepm from age to agelin. 
 Total number of observations=%d <br>\n       Look at hpijx to understand the reason of that which relies in memory size
 Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n       and note for a fixed period like estepm months */
 <hr  size=\"2\" color=\"#EC5E5E\">    /* We decided (b) to get a life expectancy respecting the most precise curvature of the
  <ul><li><h4>Parameter files</h4>\n       survival function given by stepm (the optimization length). Unfortunately it
  - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n       means that if the survival funtion is printed only each two years of age and if
  - Log file of the run: <a href=\"%s\">%s</a><br>\n       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
  - Gnuplot file name: <a href=\"%s\">%s</a></ul>\n",version,title,datafile,firstpass,lastpass,stepm, weightopt,model,imx,jmin,jmax,jmean,fileres,fileres,filelog,filelog,optionfilegnuplot,optionfilegnuplot);       results. So we changed our mind and took the option of the best precision.
   fclose(fichtm);    */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
  printinghtml(fileres,title,datafile, firstpass, lastpass, stepm, weightopt,model,imx,jmin,jmax,jmean,rfileres,popforecast,estepm,jprev1,mprev1,anprev1,jprev2,mprev2,anprev2);  
      agelim=AGESUP;
 /*------------ free_vector  -------------*/    /* If stepm=6 months */
  chdir(path);      /* Computed by stepm unit matrices, product of hstepm matrices, stored
           in an array of nhstepm length: nhstepm=10, hstepm=4, stepm=6 months */
  free_ivector(wav,1,imx);      
  free_imatrix(dh,1,lastpass-firstpass+1,1,imx);  /* nhstepm age range expressed in number of stepm */
  free_imatrix(mw,1,lastpass-firstpass+1,1,imx);      nstepm=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
  free_ivector(num,1,n);    /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
  free_vector(agedc,1,n);    /* if (stepm >= YEARM) hstepm=1;*/
  /*free_matrix(covar,1,NCOVMAX,1,n);*/    nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
  fclose(ficparo);    p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
  fclose(ficres);  
     for (age=bage; age<=fage; age ++){ 
       nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
   /*--------------- Prevalence limit --------------*/      /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
        /* if (stepm >= YEARM) hstepm=1;*/
   strcpy(filerespl,"pl");      nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
   strcat(filerespl,fileres);  
   if((ficrespl=fopen(filerespl,"w"))==NULL) {      /* If stepm=6 months */
     printf("Problem with Prev limit resultfile: %s\n", filerespl);goto end;      /* Computed by stepm unit matrices, product of hstepma matrices, stored
     fprintf(ficlog,"Problem with Prev limit resultfile: %s\n", filerespl);goto end;         in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
   }      
   printf("Computing prevalence limit: result on file '%s' \n", filerespl);      hpxij(p3mat,nhstepma,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
   fprintf(ficlog,"Computing prevalence limit: result on file '%s' \n", filerespl);      
   fprintf(ficrespl,"#Prevalence limit\n");      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
   fprintf(ficrespl,"#Age ");      
   for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);      printf("%d|",(int)age);fflush(stdout);
   fprintf(ficrespl,"\n");      fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
        
   prlim=matrix(1,nlstate,1,nlstate);      /* Computing expectancies */
   pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */      for(i=1; i<=nlstate;i++)
   oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */        for(j=1; j<=nlstate;j++)
   newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */          for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
   savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */            eij[i][j][(int)age] += (p3mat[i][j][h]+p3mat[i][j][h+1])/2.0*hf;
   oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */            
   k=0;            /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
   agebase=ageminpar;  
   agelim=agemaxpar;          }
   ftolpl=1.e-10;  
   i1=cptcoveff;      fprintf(ficreseij,"%3.0f",age );
   if (cptcovn < 1){i1=1;}      for(i=1; i<=nlstate;i++){
         eip=0;
   for(cptcov=1;cptcov<=i1;cptcov++){        for(j=1; j<=nlstate;j++){
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){          eip +=eij[i][j][(int)age];
         k=k+1;          fprintf(ficreseij,"%9.4f", eij[i][j][(int)age] );
         /*printf("cptcov=%d cptcod=%d codtab=%d nbcode=%d\n",cptcov, cptcod,Tcode[cptcode],codtab[cptcod][cptcov]);*/        }
         fprintf(ficrespl,"\n#******");        fprintf(ficreseij,"%9.4f", eip );
         printf("\n#******");      }
         fprintf(ficlog,"\n#******");      fprintf(ficreseij,"\n");
         for(j=1;j<=cptcoveff;j++) {      
           fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    }
           printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    printf("\n");
         }    fprintf(ficlog,"\n");
         fprintf(ficrespl,"******\n");    
         printf("******\n");  }
         fprintf(ficlog,"******\n");  
          void cvevsij(double ***eij, double x[], int nlstate, int stepm, int bage, int fage, double **oldm, double **savm, int cij, int estepm,double delti[],double **matcov,char strstart[] )
         for (age=agebase; age<=agelim; age++){  
           prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);  {
           fprintf(ficrespl,"%.0f",age );    /* Covariances of health expectancies eij and of total life expectancies according
           for(i=1; i<=nlstate;i++)     to initial status i, ei. .
           fprintf(ficrespl," %.5f", prlim[i][i]);    */
           fprintf(ficrespl,"\n");    int i, j, nhstepm, hstepm, h, nstepm, k, cptj, cptj2, i2, j2, ij, ji;
         }    int nhstepma, nstepma; /* Decreasing with age */
       }    double age, agelim, hf;
     }    double ***p3matp, ***p3matm, ***varhe;
   fclose(ficrespl);    double **dnewm,**doldm;
     double *xp, *xm;
   /*------------- h Pij x at various ages ------------*/    double **gp, **gm;
      double ***gradg, ***trgradg;
   strcpy(filerespij,"pij");  strcat(filerespij,fileres);    int theta;
   if((ficrespij=fopen(filerespij,"w"))==NULL) {  
     printf("Problem with Pij resultfile: %s\n", filerespij);goto end;    double eip, vip;
     fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij);goto end;  
   }    varhe=ma3x(1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int) fage);
   printf("Computing pij: result on file '%s' \n", filerespij);    xp=vector(1,npar);
   fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);    xm=vector(1,npar);
      dnewm=matrix(1,nlstate*nlstate,1,npar);
   stepsize=(int) (stepm+YEARM-1)/YEARM;    doldm=matrix(1,nlstate*nlstate,1,nlstate*nlstate);
   /*if (stepm<=24) stepsize=2;*/    
     pstamp(ficresstdeij);
   agelim=AGESUP;    fprintf(ficresstdeij,"# Health expectancies with standard errors\n");
   hstepm=stepsize*YEARM; /* Every year of age */    fprintf(ficresstdeij,"# Age");
   hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */    for(i=1; i<=nlstate;i++){
       for(j=1; j<=nlstate;j++)
   /* hstepm=1;   aff par mois*/        fprintf(ficresstdeij," e%1d%1d (SE)",i,j);
       fprintf(ficresstdeij," e%1d. ",i);
   k=0;    }
   for(cptcov=1;cptcov<=i1;cptcov++){    fprintf(ficresstdeij,"\n");
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){  
       k=k+1;    pstamp(ficrescveij);
         fprintf(ficrespij,"\n#****** ");    fprintf(ficrescveij,"# Subdiagonal matrix of covariances of health expectancies by age: cov(eij,ekl)\n");
         for(j=1;j<=cptcoveff;j++)    fprintf(ficrescveij,"# Age");
           fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    for(i=1; i<=nlstate;i++)
         fprintf(ficrespij,"******\n");      for(j=1; j<=nlstate;j++){
                cptj= (j-1)*nlstate+i;
         for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */        for(i2=1; i2<=nlstate;i2++)
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */          for(j2=1; j2<=nlstate;j2++){
           nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */            cptj2= (j2-1)*nlstate+i2;
             if(cptj2 <= cptj)
           /*      nhstepm=nhstepm*YEARM; aff par mois*/              fprintf(ficrescveij,"  %1d%1d,%1d%1d",i,j,i2,j2);
           }
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);      }
           oldm=oldms;savm=savms;    fprintf(ficrescveij,"\n");
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);      
           fprintf(ficrespij,"# Age");    if(estepm < stepm){
           for(i=1; i<=nlstate;i++)      printf ("Problem %d lower than %d\n",estepm, stepm);
             for(j=1; j<=nlstate+ndeath;j++)    }
               fprintf(ficrespij," %1d-%1d",i,j);    else  hstepm=estepm;   
           fprintf(ficrespij,"\n");    /* We compute the life expectancy from trapezoids spaced every estepm months
            for (h=0; h<=nhstepm; h++){     * This is mainly to measure the difference between two models: for example
             fprintf(ficrespij,"%d %f %f",k,agedeb, agedeb+ h*hstepm/YEARM*stepm );     * if stepm=24 months pijx are given only every 2 years and by summing them
             for(i=1; i<=nlstate;i++)     * we are calculating an estimate of the Life Expectancy assuming a linear 
               for(j=1; j<=nlstate+ndeath;j++)     * progression in between and thus overestimating or underestimating according
                 fprintf(ficrespij," %.5f", p3mat[i][j][h]);     * to the curvature of the survival function. If, for the same date, we 
             fprintf(ficrespij,"\n");     * estimate the model with stepm=1 month, we can keep estepm to 24 months
              }     * to compare the new estimate of Life expectancy with the same linear 
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);     * hypothesis. A more precise result, taking into account a more precise
           fprintf(ficrespij,"\n");     * curvature will be obtained if estepm is as small as stepm. */
         }  
     }    /* For example we decided to compute the life expectancy with the smallest unit */
   }    /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
        nhstepm is the number of hstepm from age to agelim 
   varprob(optionfilefiname, matcov, p, delti, nlstate, (int) bage, (int) fage,k,Tvar,nbcode, ncodemax);       nstepm is the number of stepm from age to agelin. 
        Look at hpijx to understand the reason of that which relies in memory size
   fclose(ficrespij);       and note for a fixed period like estepm months */
     /* We decided (b) to get a life expectancy respecting the most precise curvature of the
        survival function given by stepm (the optimization length). Unfortunately it
   /*---------- Forecasting ------------------*/       means that if the survival funtion is printed only each two years of age and if
   if((stepm == 1) && (strcmp(model,".")==0)){       you sum them up and add 1 year (area under the trapezoids) you won't get the same 
     prevforecast(fileres, anproj1,mproj1,jproj1, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anproj2,p, i1);       results. So we changed our mind and took the option of the best precision.
     if (popforecast==1) populforecast(fileres, anpyram,mpyram,jpyram, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anpyram1,p, i1);    */
   }    hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
   else{  
     erreur=108;    /* If stepm=6 months */
     printf("Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model);    /* nhstepm age range expressed in number of stepm */
     fprintf(ficlog,"Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model);    agelim=AGESUP;
   }    nstepm=(int) rint((agelim-bage)*YEARM/stepm); 
      /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
     /* if (stepm >= YEARM) hstepm=1;*/
   /*---------- Health expectancies and variances ------------*/    nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
     
   strcpy(filerest,"t");    p3matp=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
   strcat(filerest,fileres);    p3matm=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
   if((ficrest=fopen(filerest,"w"))==NULL) {    gradg=ma3x(0,nhstepm,1,npar,1,nlstate*nlstate);
     printf("Problem with total LE resultfile: %s\n", filerest);goto end;    trgradg =ma3x(0,nhstepm,1,nlstate*nlstate,1,npar);
     fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;    gp=matrix(0,nhstepm,1,nlstate*nlstate);
   }    gm=matrix(0,nhstepm,1,nlstate*nlstate);
   printf("Computing Total LEs with variances: file '%s' \n", filerest);  
   fprintf(ficlog,"Computing Total LEs with variances: file '%s' \n", filerest);    for (age=bage; age<=fage; age ++){ 
       nstepma=(int) rint((agelim-bage)*YEARM/stepm); /* Biggest nstepm */
       /* Typically if 20 years nstepm = 20*12/6=40 stepm */ 
   strcpy(filerese,"e");      /* if (stepm >= YEARM) hstepm=1;*/
   strcat(filerese,fileres);      nhstepma = nstepma/hstepm;/* Expressed in hstepm, typically nhstepma=40/4=10 */
   if((ficreseij=fopen(filerese,"w"))==NULL) {  
     printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);      /* If stepm=6 months */
     fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);      /* Computed by stepm unit matrices, product of hstepma matrices, stored
   }         in an array of nhstepma length: nhstepma=10, hstepm=4, stepm=6 months */
   printf("Computing Health Expectancies: result on file '%s' \n", filerese);      
   fprintf(ficlog,"Computing Health Expectancies: result on file '%s' \n", filerese);      hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
   
   strcpy(fileresv,"v");      /* Computing  Variances of health expectancies */
   strcat(fileresv,fileres);      /* Gradient is computed with plus gp and minus gm. Code is duplicated in order to
   if((ficresvij=fopen(fileresv,"w"))==NULL) {         decrease memory allocation */
     printf("Problem with variance resultfile: %s\n", fileresv);exit(0);      for(theta=1; theta <=npar; theta++){
     fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);        for(i=1; i<=npar; i++){ 
   }          xp[i] = x[i] + (i==theta ?delti[theta]:0);
   printf("Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);          xm[i] = x[i] - (i==theta ?delti[theta]:0);
   fprintf(ficlog,"Computing Variance-covariance of DFLEs: file '%s' \n", fileresv);        }
   calagedate=-1;        hpxij(p3matp,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, cij);  
   prevalence(ageminpar, agemax, s, agev, nlstate, imx,Tvar,nbcode, ncodemax,mint,anint,dateprev1,dateprev2, calagedate);        hpxij(p3matm,nhstepm,age,hstepm,xm,nlstate,stepm,oldm,savm, cij);  
     
   k=0;        for(j=1; j<= nlstate; j++){
   for(cptcov=1;cptcov<=i1;cptcov++){          for(i=1; i<=nlstate; i++){
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){            for(h=0; h<=nhstepm-1; h++){
       k=k+1;              gp[h][(j-1)*nlstate + i] = (p3matp[i][j][h]+p3matp[i][j][h+1])/2.;
       fprintf(ficrest,"\n#****** ");              gm[h][(j-1)*nlstate + i] = (p3matm[i][j][h]+p3matm[i][j][h+1])/2.;
       for(j=1;j<=cptcoveff;j++)            }
         fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);          }
       fprintf(ficrest,"******\n");        }
        
       fprintf(ficreseij,"\n#****** ");        for(ij=1; ij<= nlstate*nlstate; ij++)
       for(j=1;j<=cptcoveff;j++)          for(h=0; h<=nhstepm-1; h++){
         fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);            gradg[h][theta][ij]= (gp[h][ij]-gm[h][ij])/2./delti[theta];
       fprintf(ficreseij,"******\n");          }
       }/* End theta */
       fprintf(ficresvij,"\n#****** ");      
       for(j=1;j<=cptcoveff;j++)      
         fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);      for(h=0; h<=nhstepm-1; h++)
       fprintf(ficresvij,"******\n");        for(j=1; j<=nlstate*nlstate;j++)
           for(theta=1; theta <=npar; theta++)
       eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);            trgradg[h][j][theta]=gradg[h][theta][j];
       oldm=oldms;savm=savms;      
       evsij(fileres, eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov);    
         for(ij=1;ij<=nlstate*nlstate;ij++)
       vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);        for(ji=1;ji<=nlstate*nlstate;ji++)
       oldm=oldms;savm=savms;          varhe[ij][ji][(int)age] =0.;
       varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm, cptcov,cptcod,0);  
       if(popbased==1){       printf("%d|",(int)age);fflush(stdout);
         varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k, estepm, cptcov,cptcod,popbased);       fprintf(ficlog,"%d|",(int)age);fflush(ficlog);
        }       for(h=0;h<=nhstepm-1;h++){
         for(k=0;k<=nhstepm-1;k++){
            matprod2(dnewm,trgradg[h],1,nlstate*nlstate,1,npar,1,npar,matcov);
       fprintf(ficrest,"#Total LEs with variances: e.. (std) ");          matprod2(doldm,dnewm,1,nlstate*nlstate,1,npar,1,nlstate*nlstate,gradg[k]);
       for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);          for(ij=1;ij<=nlstate*nlstate;ij++)
       fprintf(ficrest,"\n");            for(ji=1;ji<=nlstate*nlstate;ji++)
               varhe[ij][ji][(int)age] += doldm[ij][ji]*hf*hf;
       epj=vector(1,nlstate+1);        }
       for(age=bage; age <=fage ;age++){      }
         prevalim(prlim, nlstate, p, age, oldm, savm,ftolpl,k);  
         if (popbased==1) {      /* Computing expectancies */
           for(i=1; i<=nlstate;i++)      hpxij(p3matm,nhstepm,age,hstepm,x,nlstate,stepm,oldm, savm, cij);  
             prlim[i][i]=probs[(int)age][i][k];      for(i=1; i<=nlstate;i++)
         }        for(j=1; j<=nlstate;j++)
                  for (h=0, eij[i][j][(int)age]=0; h<=nhstepm-1; h++){
         fprintf(ficrest," %4.0f",age);            eij[i][j][(int)age] += (p3matm[i][j][h]+p3matm[i][j][h+1])/2.0*hf;
         for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){            
           for(i=1, epj[j]=0.;i <=nlstate;i++) {            /* if((int)age==70)printf("i=%2d,j=%2d,h=%2d,age=%3d,%9.4f,%9.4f,%9.4f\n",i,j,h,(int)age,p3mat[i][j][h],hf,eij[i][j][(int)age]);*/
             epj[j] += prlim[i][i]*eij[i][j][(int)age];  
             /*  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/          }
           }  
           epj[nlstate+1] +=epj[j];      fprintf(ficresstdeij,"%3.0f",age );
         }      for(i=1; i<=nlstate;i++){
         eip=0.;
         for(i=1, vepp=0.;i <=nlstate;i++)        vip=0.;
           for(j=1;j <=nlstate;j++)        for(j=1; j<=nlstate;j++){
             vepp += vareij[i][j][(int)age];          eip += eij[i][j][(int)age];
         fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));          for(k=1; k<=nlstate;k++) /* Sum on j and k of cov(eij,eik) */
         for(j=1;j <=nlstate;j++){            vip += varhe[(j-1)*nlstate+i][(k-1)*nlstate+i][(int)age];
           fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));          fprintf(ficresstdeij," %9.4f (%.4f)", eij[i][j][(int)age], sqrt(varhe[(j-1)*nlstate+i][(j-1)*nlstate+i][(int)age]) );
         }        }
         fprintf(ficrest,"\n");        fprintf(ficresstdeij," %9.4f (%.4f)", eip, sqrt(vip));
       }      }
     }      fprintf(ficresstdeij,"\n");
   }  
 free_matrix(mint,1,maxwav,1,n);      fprintf(ficrescveij,"%3.0f",age );
     free_matrix(anint,1,maxwav,1,n); free_imatrix(s,1,maxwav+1,1,n);      for(i=1; i<=nlstate;i++)
     free_vector(weight,1,n);        for(j=1; j<=nlstate;j++){
   fclose(ficreseij);          cptj= (j-1)*nlstate+i;
   fclose(ficresvij);          for(i2=1; i2<=nlstate;i2++)
   fclose(ficrest);            for(j2=1; j2<=nlstate;j2++){
   fclose(ficpar);              cptj2= (j2-1)*nlstate+i2;
   free_vector(epj,1,nlstate+1);              if(cptj2 <= cptj)
                  fprintf(ficrescveij," %.4f", varhe[cptj][cptj2][(int)age]);
   /*------- Variance limit prevalence------*/              }
         }
   strcpy(fileresvpl,"vpl");      fprintf(ficrescveij,"\n");
   strcat(fileresvpl,fileres);     
   if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {    }
     printf("Problem with variance prev lim resultfile: %s\n", fileresvpl);    free_matrix(gm,0,nhstepm,1,nlstate*nlstate);
     exit(0);    free_matrix(gp,0,nhstepm,1,nlstate*nlstate);
   }    free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate*nlstate);
   printf("Computing Variance-covariance of Prevalence limit: file '%s' \n", fileresvpl);    free_ma3x(trgradg,0,nhstepm,1,nlstate*nlstate,1,npar);
     free_ma3x(p3matm,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
   k=0;    free_ma3x(p3matp,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
   for(cptcov=1;cptcov<=i1;cptcov++){    printf("\n");
     for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){    fprintf(ficlog,"\n");
       k=k+1;  
       fprintf(ficresvpl,"\n#****** ");    free_vector(xm,1,npar);
       for(j=1;j<=cptcoveff;j++)    free_vector(xp,1,npar);
         fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtab[k][j]]);    free_matrix(dnewm,1,nlstate*nlstate,1,npar);
       fprintf(ficresvpl,"******\n");    free_matrix(doldm,1,nlstate*nlstate,1,nlstate*nlstate);
          free_ma3x(varhe,1,nlstate*nlstate,1,nlstate*nlstate,(int) bage, (int)fage);
       varpl=matrix(1,nlstate,(int) bage, (int) fage);  }
       oldm=oldms;savm=savms;  
      varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl,k);  /************ Variance ******************/
     }   void varevsij(char optionfilefiname[], double ***vareij, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, int estepm, int cptcov, int cptcod, int popbased, int mobilav, char strstart[])
  }  {
     /* Variance of health expectancies */
   fclose(ficresvpl);    /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double ** savm,double ftolpl);*/
     /* double **newm;*/
   /*---------- End : free ----------------*/    /* int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav)*/
   free_matrix(varpl,1,nlstate,(int) bage, (int)fage);    
      int movingaverage();
   free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);    double **dnewm,**doldm;
   free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);    double **dnewmp,**doldmp;
      int i, j, nhstepm, hstepm, h, nstepm ;
      int k;
   free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);    double *xp;
   free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);    double **gp, **gm;  /* for var eij */
   free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);    double ***gradg, ***trgradg; /*for var eij */
   free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);    double **gradgp, **trgradgp; /* for var p point j */
      double *gpp, *gmp; /* for var p point j */
   free_matrix(matcov,1,npar,1,npar);    double **varppt; /* for var p point j nlstate to nlstate+ndeath */
   free_vector(delti,1,npar);    double ***p3mat;
   free_matrix(agev,1,maxwav,1,imx);    double age,agelim, hf;
   free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);    double ***mobaverage;
     int theta;
   fprintf(fichtm,"\n</body>");    char digit[4];
   fclose(fichtm);    char digitp[25];
   fclose(ficgp);  
      char fileresprobmorprev[FILENAMELENGTH];
   
   if(erreur >0){    if(popbased==1){
     printf("End of Imach with error or warning %d\n",erreur);      if(mobilav!=0)
     fprintf(ficlog,"End of Imach with error or warning %d\n",erreur);        strcpy(digitp,"-POPULBASED-MOBILAV_");
   }else{      else strcpy(digitp,"-POPULBASED-NOMOBIL_");
    printf("End of Imach\n");    }
    fprintf(ficlog,"End of Imach\n");    else 
   }      strcpy(digitp,"-STABLBASED_");
   printf("See log file on %s\n",filelog);  
   fclose(ficlog);    if (mobilav!=0) {
   /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */      mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
        if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){
   /* printf("Total time was %d Sec. %d uSec.\n", end_time.tv_sec -start_time.tv_sec, end_time.tv_usec -start_time.tv_usec);*/        fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
   /*printf("Total time was %d uSec.\n", total_usecs);*/        printf(" Error in movingaverage mobilav=%d\n",mobilav);
   /*------ End -----------*/      }
     }
   
  end:    strcpy(fileresprobmorprev,"PRMORPREV-"); 
 #ifdef windows    sprintf(digit,"%-d",ij);
   /* chdir(pathcd);*/    /*printf("DIGIT=%s, ij=%d ijr=%-d|\n",digit, ij,ij);*/
 #endif    strcat(fileresprobmorprev,digit); /* Tvar to be done */
  /*system("wgnuplot graph.plt");*/    strcat(fileresprobmorprev,digitp); /* Popbased or not, mobilav or not */
  /*system("../gp37mgw/wgnuplot graph.plt");*/    strcat(fileresprobmorprev,fileresu);
  /*system("cd ../gp37mgw");*/    if((ficresprobmorprev=fopen(fileresprobmorprev,"w"))==NULL) {
  /* system("..\\gp37mgw\\wgnuplot graph.plt");*/      printf("Problem with resultfile: %s\n", fileresprobmorprev);
  strcpy(plotcmd,GNUPLOTPROGRAM);      fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobmorprev);
  strcat(plotcmd," ");    }
  strcat(plotcmd,optionfilegnuplot);    printf("Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
  system(plotcmd);    fprintf(ficlog,"Computing total mortality p.j=w1*p1j+w2*p2j+..: result on file '%s' \n",fileresprobmorprev);
     pstamp(ficresprobmorprev);
 #ifdef windows    fprintf(ficresprobmorprev,"# probabilities of dying before estepm=%d months for people of exact age and weighted probabilities w1*p1j+w2*p2j+... stand dev in()\n",estepm);
   while (z[0] != 'q') {    fprintf(ficresprobmorprev,"# Age cov=%-d",ij);
     /* chdir(path); */    for(j=nlstate+1; j<=(nlstate+ndeath);j++){
     printf("\nType e to edit output files, g to graph again, c to start again, and q for exiting: ");      fprintf(ficresprobmorprev," p.%-d SE",j);
     scanf("%s",z);      for(i=1; i<=nlstate;i++)
     if (z[0] == 'c') system("./imach");        fprintf(ficresprobmorprev," w%1d p%-d%-d",i,i,j);
     else if (z[0] == 'e') system(optionfilehtm);    }  
     else if (z[0] == 'g') system(plotcmd);    fprintf(ficresprobmorprev,"\n");
     else if (z[0] == 'q') exit(0);    
   }    fprintf(ficgp,"\n# Routine varevsij");
 #endif    fprintf(ficgp,"\nunset title \n");
 }  /* fprintf(fichtm, "#Local time at start: %s", strstart);*/
     fprintf(fichtm,"\n<li><h4> Computing probabilities of dying over estepm months as a weighted average (i.e global mortality independent of initial healh state)</h4></li>\n");
     fprintf(fichtm,"\n<br>%s  <br>\n",digitp);
   /*   } */
     varppt = matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     pstamp(ficresvij);
     fprintf(ficresvij,"# Variance and covariance of health expectancies e.j \n#  (weighted average of eij where weights are ");
     if(popbased==1)
       fprintf(ficresvij,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d\n",mobilav);
     else
       fprintf(ficresvij,"the age specific period (stable) prevalences in each health state \n");
     fprintf(ficresvij,"# Age");
     for(i=1; i<=nlstate;i++)
       for(j=1; j<=nlstate;j++)
         fprintf(ficresvij," Cov(e.%1d, e.%1d)",i,j);
     fprintf(ficresvij,"\n");
   
     xp=vector(1,npar);
     dnewm=matrix(1,nlstate,1,npar);
     doldm=matrix(1,nlstate,1,nlstate);
     dnewmp= matrix(nlstate+1,nlstate+ndeath,1,npar);
     doldmp= matrix(nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
   
     gradgp=matrix(1,npar,nlstate+1,nlstate+ndeath);
     gpp=vector(nlstate+1,nlstate+ndeath);
     gmp=vector(nlstate+1,nlstate+ndeath);
     trgradgp =matrix(nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
     
     if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;   
     /* For example we decided to compute the life expectancy with the smallest unit */
     /* hstepm beeing the number of stepms, if hstepm=1 the length of hstepm is stepm. 
        nhstepm is the number of hstepm from age to agelim 
        nstepm is the number of stepm from age to agelim. 
        Look at function hpijx to understand why because of memory size limitations, 
        we decided (b) to get a life expectancy respecting the most precise curvature of the
        survival function given by stepm (the optimization length). Unfortunately it
        means that if the survival funtion is printed every two years of age and if
        you sum them up and add 1 year (area under the trapezoids) you won't get the same 
        results. So we changed our mind and took the option of the best precision.
     */
     hstepm=hstepm/stepm; /* Typically in stepm units, if stepm=6 & estepm=24 , = 24/6 months = 4 */ 
     agelim = AGESUP;
     for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
       nstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
       nhstepm = nstepm/hstepm;/* Expressed in hstepm, typically nhstepm=40/4=10 */
       p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
       gradg=ma3x(0,nhstepm,1,npar,1,nlstate);
       gp=matrix(0,nhstepm,1,nlstate);
       gm=matrix(0,nhstepm,1,nlstate);
   
   
       for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){ /* Computes gradient x + delta*/
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
         }
   
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
   
         if (popbased==1) {
           if(mobilav ==0){
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=probs[(int)age][i][ij];
           }else{ /* mobilav */ 
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=mobaverage[(int)age][i][ij];
           }
         }
     
         hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  /* Returns p3mat[i][j][h] for h=1 to nhstepm */
         for(j=1; j<= nlstate; j++){
           for(h=0; h<=nhstepm; h++){
             for(i=1, gp[h][j]=0.;i<=nlstate;i++)
               gp[h][j] += prlim[i][i]*p3mat[i][j][h];
           }
         }
         /* Next for computing probability of death (h=1 means
            computed over hstepm matrices product = hstepm*stepm months) 
            as a weighted average of prlim.
         */
         for(j=nlstate+1;j<=nlstate+ndeath;j++){
           for(i=1,gpp[j]=0.; i<= nlstate; i++)
             gpp[j] += prlim[i][i]*p3mat[i][j][1];
         }    
         /* end probability of death */
   
         for(i=1; i<=npar; i++) /* Computes gradient x - delta */
           xp[i] = x[i] - (i==theta ?delti[theta]:0);
   
         prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp, ij);
    
         if (popbased==1) {
           if(mobilav ==0){
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=probs[(int)age][i][ij];
           }else{ /* mobilav */ 
             for(i=1; i<=nlstate;i++)
               prlim[i][i]=mobaverage[(int)age][i][ij];
           }
         }
   
         hpxij(p3mat,nhstepm,age,hstepm,xp,nlstate,stepm,oldm,savm, ij);  
   
         for(j=1; j<= nlstate; j++){  /* Sum of wi * eij = e.j */
           for(h=0; h<=nhstepm; h++){
             for(i=1, gm[h][j]=0.;i<=nlstate;i++)
               gm[h][j] += prlim[i][i]*p3mat[i][j][h];
           }
         }
         /* This for computing probability of death (h=1 means
            computed over hstepm matrices product = hstepm*stepm months) 
            as a weighted average of prlim.
         */
         for(j=nlstate+1;j<=nlstate+ndeath;j++){
           for(i=1,gmp[j]=0.; i<= nlstate; i++)
            gmp[j] += prlim[i][i]*p3mat[i][j][1];
         }    
         /* end probability of death */
   
         for(j=1; j<= nlstate; j++) /* vareij */
           for(h=0; h<=nhstepm; h++){
             gradg[h][theta][j]= (gp[h][j]-gm[h][j])/2./delti[theta];
           }
   
         for(j=nlstate+1; j<= nlstate+ndeath; j++){ /* var mu */
           gradgp[theta][j]= (gpp[j]-gmp[j])/2./delti[theta];
         }
   
       } /* End theta */
   
       trgradg =ma3x(0,nhstepm,1,nlstate,1,npar); /* veij */
   
       for(h=0; h<=nhstepm; h++) /* veij */
         for(j=1; j<=nlstate;j++)
           for(theta=1; theta <=npar; theta++)
             trgradg[h][j][theta]=gradg[h][theta][j];
   
       for(j=nlstate+1; j<=nlstate+ndeath;j++) /* mu */
         for(theta=1; theta <=npar; theta++)
           trgradgp[j][theta]=gradgp[theta][j];
     
   
       hf=hstepm*stepm/YEARM;  /* Duration of hstepm expressed in year unit. */
       for(i=1;i<=nlstate;i++)
         for(j=1;j<=nlstate;j++)
           vareij[i][j][(int)age] =0.;
   
       for(h=0;h<=nhstepm;h++){
         for(k=0;k<=nhstepm;k++){
           matprod2(dnewm,trgradg[h],1,nlstate,1,npar,1,npar,matcov);
           matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg[k]);
           for(i=1;i<=nlstate;i++)
             for(j=1;j<=nlstate;j++)
               vareij[i][j][(int)age] += doldm[i][j]*hf*hf;
         }
       }
     
       /* pptj */
       matprod2(dnewmp,trgradgp,nlstate+1,nlstate+ndeath,1,npar,1,npar,matcov);
       matprod2(doldmp,dnewmp,nlstate+1,nlstate+ndeath,1,npar,nlstate+1,nlstate+ndeath,gradgp);
       for(j=nlstate+1;j<=nlstate+ndeath;j++)
         for(i=nlstate+1;i<=nlstate+ndeath;i++)
           varppt[j][i]=doldmp[j][i];
       /* end ppptj */
       /*  x centered again */
   
       prevalim(prlim,nlstate,x,age,oldm,savm,ftolpl,ncvyearp,ij);
    
       if (popbased==1) {
         if(mobilav ==0){
           for(i=1; i<=nlstate;i++)
             prlim[i][i]=probs[(int)age][i][ij];
         }else{ /* mobilav */ 
           for(i=1; i<=nlstate;i++)
             prlim[i][i]=mobaverage[(int)age][i][ij];
         }
       }
                
       /* This for computing probability of death (h=1 means
          computed over hstepm (estepm) matrices product = hstepm*stepm months) 
          as a weighted average of prlim.
       */
       hpxij(p3mat,nhstepm,age,hstepm,x,nlstate,stepm,oldm,savm, ij);  
       for(j=nlstate+1;j<=nlstate+ndeath;j++){
         for(i=1,gmp[j]=0.;i<= nlstate; i++) 
           gmp[j] += prlim[i][i]*p3mat[i][j][1]; 
       }    
       /* end probability of death */
   
       fprintf(ficresprobmorprev,"%3d %d ",(int) age, ij);
       for(j=nlstate+1; j<=(nlstate+ndeath);j++){
         fprintf(ficresprobmorprev," %11.3e %11.3e",gmp[j], sqrt(varppt[j][j]));
         for(i=1; i<=nlstate;i++){
           fprintf(ficresprobmorprev," %11.3e %11.3e ",prlim[i][i],p3mat[i][j][1]);
         }
       } 
       fprintf(ficresprobmorprev,"\n");
   
       fprintf(ficresvij,"%.0f ",age );
       for(i=1; i<=nlstate;i++)
         for(j=1; j<=nlstate;j++){
           fprintf(ficresvij," %.4f", vareij[i][j][(int)age]);
         }
       fprintf(ficresvij,"\n");
       free_matrix(gp,0,nhstepm,1,nlstate);
       free_matrix(gm,0,nhstepm,1,nlstate);
       free_ma3x(gradg,0,nhstepm,1,npar,1,nlstate);
       free_ma3x(trgradg,0,nhstepm,1,nlstate,1,npar);
       free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
     } /* End age */
     free_vector(gpp,nlstate+1,nlstate+ndeath);
     free_vector(gmp,nlstate+1,nlstate+ndeath);
     free_matrix(gradgp,1,npar,nlstate+1,nlstate+ndeath);
     free_matrix(trgradgp,nlstate+1,nlstate+ndeath,1,npar); /* mu or p point j*/
     /* fprintf(ficgp,"\nunset parametric;unset label; set ter png small size 320, 240"); */
     fprintf(ficgp,"\nunset parametric;unset label; set ter svg size 640, 480");
     /* for(j=nlstate+1; j<= nlstate+ndeath; j++){ *//* Only the first actually */
     fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Force of mortality (year-1)\";");
     fprintf(ficgp,"\nset out \"%s%s.svg\";",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
   /*   fprintf(ficgp,"\n plot \"%s\"  u 1:($3*%6.3f) not w l 1 ",fileresprobmorprev,YEARM/estepm); */
   /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)*%6.3f) t \"95\%% interval\" w l 2 ",fileresprobmorprev,YEARM/estepm); */
   /*   fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)*%6.3f) not w l 2 ",fileresprobmorprev,YEARM/estepm); */
     fprintf(ficgp,"\n plot \"%s\"  u 1:($3) not w l lt 1 ",subdirf(fileresprobmorprev));
     fprintf(ficgp,"\n replot \"%s\"  u 1:(($3+1.96*$4)) t \"95%% interval\" w l lt 2 ",subdirf(fileresprobmorprev));
     fprintf(ficgp,"\n replot \"%s\"  u 1:(($3-1.96*$4)) not w l lt 2 ",subdirf(fileresprobmorprev));
     fprintf(fichtm,"\n<br> File (multiple files are possible if covariates are present): <A href=\"%s\">%s</a>\n",subdirf(fileresprobmorprev),subdirf(fileresprobmorprev));
     fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months. <br> <img src=\"%s%s.svg\"> <br>\n", estepm,subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
     /*  fprintf(fichtm,"\n<br> Probability is computed over estepm=%d months and then divided by estepm and multiplied by %.0f in order to have the probability to die over a year <br> <img src=\"varmuptjgr%s%s.svg\"> <br>\n", stepm,YEARM,digitp,digit);
   */
   /*   fprintf(ficgp,"\nset out \"varmuptjgr%s%s%s.svg\";replot;",digitp,optionfilefiname,digit); */
     fprintf(ficgp,"\nset out;\nset out \"%s%s.svg\";replot;set out;\n",subdirf3(optionfilefiname,"VARMUPTJGR-",digitp),digit);
   
     free_vector(xp,1,npar);
     free_matrix(doldm,1,nlstate,1,nlstate);
     free_matrix(dnewm,1,nlstate,1,npar);
     free_matrix(doldmp,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     free_matrix(dnewmp,nlstate+1,nlstate+ndeath,1,npar);
     free_matrix(varppt,nlstate+1,nlstate+ndeath,nlstate+1,nlstate+ndeath);
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     fclose(ficresprobmorprev);
     fflush(ficgp);
     fflush(fichtm); 
   }  /* end varevsij */
   
   /************ Variance of prevlim ******************/
    void varprevlim(char fileres[], double **varpl, double **matcov, double x[], double delti[], int nlstate, int stepm, double bage, double fage, double **oldm, double **savm, double **prlim, double ftolpl, int *ncvyearp, int ij, char strstart[])
   {
     /* Variance of prevalence limit  for each state ij using current parameters x[] and estimates of neighbourhood give by delti*/
     /*  double **prevalim(double **prlim, int nlstate, double *xp, double age, double **oldm, double **savm,double ftolpl);*/
   
     double **dnewm,**doldm;
     int i, j, nhstepm, hstepm;
     double *xp;
     double *gp, *gm;
     double **gradg, **trgradg;
     double **mgm, **mgp;
     double age,agelim;
     int theta;
     
     pstamp(ficresvpl);
     fprintf(ficresvpl,"# Standard deviation of period (stable) prevalences \n");
     fprintf(ficresvpl,"# Age");
     for(i=1; i<=nlstate;i++)
         fprintf(ficresvpl," %1d-%1d",i,i);
     fprintf(ficresvpl,"\n");
   
     xp=vector(1,npar);
     dnewm=matrix(1,nlstate,1,npar);
     doldm=matrix(1,nlstate,1,nlstate);
     
     hstepm=1*YEARM; /* Every year of age */
     hstepm=hstepm/stepm; /* Typically in stepm units, if j= 2 years, = 2/6 months = 4 */ 
     agelim = AGESUP;
     for (age=bage; age<=fage; age ++){ /* If stepm=6 months */
       nhstepm=(int) rint((agelim-age)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
       if (stepm >= YEARM) hstepm=1;
       nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
       gradg=matrix(1,npar,1,nlstate);
       mgp=matrix(1,npar,1,nlstate);
       mgm=matrix(1,npar,1,nlstate);
       gp=vector(1,nlstate);
       gm=vector(1,nlstate);
   
       for(theta=1; theta <=npar; theta++){
         for(i=1; i<=npar; i++){ /* Computes gradient */
           xp[i] = x[i] + (i==theta ?delti[theta]:0);
         }
         if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
           prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
         else
           prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
         for(i=1;i<=nlstate;i++){
           gp[i] = prlim[i][i];
           mgp[theta][i] = prlim[i][i];
         }
         for(i=1; i<=npar; i++) /* Computes gradient */
           xp[i] = x[i] - (i==theta ?delti[theta]:0);
         if((int)age==79 ||(int)age== 80 ||(int)age== 81 )
           prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
         else
           prevalim(prlim,nlstate,xp,age,oldm,savm,ftolpl,ncvyearp,ij);
         for(i=1;i<=nlstate;i++){
           gm[i] = prlim[i][i];
           mgm[theta][i] = prlim[i][i];
         }
         for(i=1;i<=nlstate;i++)
           gradg[theta][i]= (gp[i]-gm[i])/2./delti[theta];
         /* gradg[theta][2]= -gradg[theta][1]; */ /* For testing if nlstate=2 */
       } /* End theta */
   
       trgradg =matrix(1,nlstate,1,npar);
   
       for(j=1; j<=nlstate;j++)
         for(theta=1; theta <=npar; theta++)
           trgradg[j][theta]=gradg[theta][j];
       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
       /*   printf("\nmgm mgp %d ",(int)age); */
       /*   for(j=1; j<=nlstate;j++){ */
       /*  printf(" %d ",j); */
       /*  for(theta=1; theta <=npar; theta++) */
       /*    printf(" %d %lf %lf",theta,mgm[theta][j],mgp[theta][j]); */
       /*  printf("\n "); */
       /*   } */
       /* } */
       /* if((int)age==79 ||(int)age== 80 ||(int)age== 81 ){ */
       /*   printf("\n gradg %d ",(int)age); */
       /*   for(j=1; j<=nlstate;j++){ */
       /*  printf("%d ",j); */
       /*  for(theta=1; theta <=npar; theta++) */
       /*    printf("%d %lf ",theta,gradg[theta][j]); */
       /*  printf("\n "); */
       /*   } */
       /* } */
   
       for(i=1;i<=nlstate;i++)
         varpl[i][(int)age] =0.;
       if((int)age==79 ||(int)age== 80  ||(int)age== 81){
       matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
       matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
       }else{
       matprod2(dnewm,trgradg,1,nlstate,1,npar,1,npar,matcov);
       matprod2(doldm,dnewm,1,nlstate,1,npar,1,nlstate,gradg);
       }
       for(i=1;i<=nlstate;i++)
         varpl[i][(int)age] = doldm[i][i]; /* Covariances are useless */
   
       fprintf(ficresvpl,"%.0f ",age );
       for(i=1; i<=nlstate;i++)
         fprintf(ficresvpl," %.5f (%.5f)",prlim[i][i],sqrt(varpl[i][(int)age]));
       fprintf(ficresvpl,"\n");
       free_vector(gp,1,nlstate);
       free_vector(gm,1,nlstate);
       free_matrix(mgm,1,npar,1,nlstate);
       free_matrix(mgp,1,npar,1,nlstate);
       free_matrix(gradg,1,npar,1,nlstate);
       free_matrix(trgradg,1,nlstate,1,npar);
     } /* End age */
   
     free_vector(xp,1,npar);
     free_matrix(doldm,1,nlstate,1,npar);
     free_matrix(dnewm,1,nlstate,1,nlstate);
   
   }
   
   /************ Variance of one-step probabilities  ******************/
   void varprob(char optionfilefiname[], double **matcov, double x[], double delti[], int nlstate, double bage, double fage, int ij, int *Tvar, int **nbcode, int *ncodemax, char strstart[])
   {
     int i, j=0,  k1, l1, tj;
     int k2, l2, j1,  z1;
     int k=0, l;
     int first=1, first1, first2;
     double cv12, mu1, mu2, lc1, lc2, v12, v21, v11, v22,v1,v2, c12, tnalp;
     double **dnewm,**doldm;
     double *xp;
     double *gp, *gm;
     double **gradg, **trgradg;
     double **mu;
     double age, cov[NCOVMAX+1];
     double std=2.0; /* Number of standard deviation wide of confidence ellipsoids */
     int theta;
     char fileresprob[FILENAMELENGTH];
     char fileresprobcov[FILENAMELENGTH];
     char fileresprobcor[FILENAMELENGTH];
     double ***varpij;
   
     strcpy(fileresprob,"PROB_"); 
     strcat(fileresprob,fileres);
     if((ficresprob=fopen(fileresprob,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprob);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprob);
     }
     strcpy(fileresprobcov,"PROBCOV_"); 
     strcat(fileresprobcov,fileresu);
     if((ficresprobcov=fopen(fileresprobcov,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobcov);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcov);
     }
     strcpy(fileresprobcor,"PROBCOR_"); 
     strcat(fileresprobcor,fileresu);
     if((ficresprobcor=fopen(fileresprobcor,"w"))==NULL) {
       printf("Problem with resultfile: %s\n", fileresprobcor);
       fprintf(ficlog,"Problem with resultfile: %s\n", fileresprobcor);
     }
     printf("Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
     fprintf(ficlog,"Computing standard deviation of one-step probabilities: result on file '%s' \n",fileresprob);
     printf("Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
     fprintf(ficlog,"Computing matrix of variance covariance of one-step probabilities: result on file '%s' \n",fileresprobcov);
     printf("and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
     fprintf(ficlog,"and correlation matrix of one-step probabilities: result on file '%s' \n",fileresprobcor);
     pstamp(ficresprob);
     fprintf(ficresprob,"#One-step probabilities and stand. devi in ()\n");
     fprintf(ficresprob,"# Age");
     pstamp(ficresprobcov);
     fprintf(ficresprobcov,"#One-step probabilities and covariance matrix\n");
     fprintf(ficresprobcov,"# Age");
     pstamp(ficresprobcor);
     fprintf(ficresprobcor,"#One-step probabilities and correlation matrix\n");
     fprintf(ficresprobcor,"# Age");
   
   
     for(i=1; i<=nlstate;i++)
       for(j=1; j<=(nlstate+ndeath);j++){
         fprintf(ficresprob," p%1d-%1d (SE)",i,j);
         fprintf(ficresprobcov," p%1d-%1d ",i,j);
         fprintf(ficresprobcor," p%1d-%1d ",i,j);
       }  
    /* fprintf(ficresprob,"\n");
     fprintf(ficresprobcov,"\n");
     fprintf(ficresprobcor,"\n");
    */
     xp=vector(1,npar);
     dnewm=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
     doldm=matrix(1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
     mu=matrix(1,(nlstate)*(nlstate+ndeath), (int) bage, (int)fage);
     varpij=ma3x(1,nlstate*(nlstate+ndeath),1,nlstate*(nlstate+ndeath),(int) bage, (int) fage);
     first=1;
     fprintf(ficgp,"\n# Routine varprob");
     fprintf(fichtm,"\n<li><h4> Computing and drawing one step probabilities with their confidence intervals</h4></li>\n");
     fprintf(fichtm,"\n");
   
     fprintf(fichtm,"\n<li><h4> <a href=\"%s\">Matrix of variance-covariance of one-step probabilities (drawings)</a></h4> this page is important in order to visualize confidence intervals and especially correlation between disability and recovery, or more generally, way in and way back.</li>\n",optionfilehtmcov);
     fprintf(fichtmcov,"Current page is file <a href=\"%s\">%s</a><br>\n\n<h4>Matrix of variance-covariance of pairs of step probabilities</h4>\n",optionfilehtmcov, optionfilehtmcov);
     fprintf(fichtmcov,"\nEllipsoids of confidence centered on point (p<inf>ij</inf>, p<inf>kl</inf>) are estimated \
   and drawn. It helps understanding how is the covariance between two incidences.\
    They are expressed in year<sup>-1</sup> in order to be less dependent of stepm.<br>\n");
     fprintf(fichtmcov,"\n<br> Contour plot corresponding to x'cov<sup>-1</sup>x = 4 (where x is the column vector (pij,pkl)) are drawn. \
   It can be understood this way: if pij and pkl where uncorrelated the (2x2) matrix of covariance \
   would have been (1/(var pij), 0 , 0, 1/(var pkl)), and the confidence interval would be 2 \
   standard deviations wide on each axis. <br>\
    Now, if both incidences are correlated (usual case) we diagonalised the inverse of the covariance matrix\
    and made the appropriate rotation to look at the uncorrelated principal directions.<br>\
   To be simple, these graphs help to understand the significativity of each parameter in relation to a second other one.<br> \n");
   
     cov[1]=1;
     /* tj=cptcoveff; */
     tj = (int) pow(2,cptcoveff);
     if (cptcovn<1) {tj=1;ncodemax[1]=1;}
     j1=0;
     for(j1=1; j1<=tj;j1++){
       /*for(i1=1; i1<=ncodemax[t];i1++){ */
       /*j1++;*/
         if  (cptcovn>0) {
           fprintf(ficresprob, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprob, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
           fprintf(ficresprob, "**********\n#\n");
           fprintf(ficresprobcov, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcov, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
           fprintf(ficresprobcov, "**********\n#\n");
           
           fprintf(ficgp, "\n#********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficgp, " V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
           fprintf(ficgp, "**********\n#\n");
           
           
           fprintf(fichtmcov, "\n<hr  size=\"2\" color=\"#EC5E5E\">********** Variable "); 
           for (z1=1; z1<=cptcoveff; z1++) fprintf(fichtm, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
           fprintf(fichtmcov, "**********\n<hr size=\"2\" color=\"#EC5E5E\">");
           
           fprintf(ficresprobcor, "\n#********** Variable ");    
           for (z1=1; z1<=cptcoveff; z1++) fprintf(ficresprobcor, "V%d=%d ",Tvaraff[z1],nbcode[Tvaraff[z1]][codtabm(j1,z1)]);
           fprintf(ficresprobcor, "**********\n#");    
         }
         
         gradg=matrix(1,npar,1,(nlstate)*(nlstate+ndeath));
         trgradg=matrix(1,(nlstate)*(nlstate+ndeath),1,npar);
         gp=vector(1,(nlstate)*(nlstate+ndeath));
         gm=vector(1,(nlstate)*(nlstate+ndeath));
         for (age=bage; age<=fage; age ++){ 
           cov[2]=age;
           if(nagesqr==1)
             cov[3]= age*age;
           for (k=1; k<=cptcovn;k++) {
             cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,k)];
             /*cov[2+nagesqr+k]=nbcode[Tvar[k]][codtabm(j1,Tvar[k])];*//* j1 1 2 3 4
                                                            * 1  1 1 1 1
                                                            * 2  2 1 1 1
                                                            * 3  1 2 1 1
                                                            */
             /* nbcode[1][1]=0 nbcode[1][2]=1;*/
           }
           /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=cov[2+Tage[k]]*cov[2]; */
           for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,k)]*cov[2];
           for (k=1; k<=cptcovprod;k++)
             cov[2+nagesqr+Tprod[k]]=nbcode[Tvard[k][1]][codtabm(ij,k)]*nbcode[Tvard[k][2]][codtabm(ij,k)];
           
       
           for(theta=1; theta <=npar; theta++){
             for(i=1; i<=npar; i++)
               xp[i] = x[i] + (i==theta ?delti[theta]:(double)0);
             
             pmij(pmmij,cov,ncovmodel,xp,nlstate);
             
             k=0;
             for(i=1; i<= (nlstate); i++){
               for(j=1; j<=(nlstate+ndeath);j++){
                 k=k+1;
                 gp[k]=pmmij[i][j];
               }
             }
             
             for(i=1; i<=npar; i++)
               xp[i] = x[i] - (i==theta ?delti[theta]:(double)0);
       
             pmij(pmmij,cov,ncovmodel,xp,nlstate);
             k=0;
             for(i=1; i<=(nlstate); i++){
               for(j=1; j<=(nlstate+ndeath);j++){
                 k=k+1;
                 gm[k]=pmmij[i][j];
               }
             }
        
             for(i=1; i<= (nlstate)*(nlstate+ndeath); i++) 
               gradg[theta][i]=(gp[i]-gm[i])/(double)2./delti[theta];  
           }
   
           for(j=1; j<=(nlstate)*(nlstate+ndeath);j++)
             for(theta=1; theta <=npar; theta++)
               trgradg[j][theta]=gradg[theta][j];
           
           matprod2(dnewm,trgradg,1,(nlstate)*(nlstate+ndeath),1,npar,1,npar,matcov); 
           matprod2(doldm,dnewm,1,(nlstate)*(nlstate+ndeath),1,npar,1,(nlstate)*(nlstate+ndeath),gradg);
   
           pmij(pmmij,cov,ncovmodel,x,nlstate);
           
           k=0;
           for(i=1; i<=(nlstate); i++){
             for(j=1; j<=(nlstate+ndeath);j++){
               k=k+1;
               mu[k][(int) age]=pmmij[i][j];
             }
           }
           for(i=1;i<=(nlstate)*(nlstate+ndeath);i++)
             for(j=1;j<=(nlstate)*(nlstate+ndeath);j++)
               varpij[i][j][(int)age] = doldm[i][j];
   
           /*printf("\n%d ",(int)age);
             for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
             printf("%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
             fprintf(ficlog,"%e [%e ;%e] ",gm[i],gm[i]-2*sqrt(doldm[i][i]),gm[i]+2*sqrt(doldm[i][i]));
             }*/
   
           fprintf(ficresprob,"\n%d ",(int)age);
           fprintf(ficresprobcov,"\n%d ",(int)age);
           fprintf(ficresprobcor,"\n%d ",(int)age);
   
           for (i=1; i<=(nlstate)*(nlstate+ndeath);i++)
             fprintf(ficresprob,"%11.3e (%11.3e) ",mu[i][(int) age],sqrt(varpij[i][i][(int)age]));
           for (i=1; i<=(nlstate)*(nlstate+ndeath);i++){
             fprintf(ficresprobcov,"%11.3e ",mu[i][(int) age]);
             fprintf(ficresprobcor,"%11.3e ",mu[i][(int) age]);
           }
           i=0;
           for (k=1; k<=(nlstate);k++){
             for (l=1; l<=(nlstate+ndeath);l++){ 
               i++;
               fprintf(ficresprobcov,"\n%d %d-%d",(int)age,k,l);
               fprintf(ficresprobcor,"\n%d %d-%d",(int)age,k,l);
               for (j=1; j<=i;j++){
                 /* printf(" k=%d l=%d i=%d j=%d\n",k,l,i,j);fflush(stdout); */
                 fprintf(ficresprobcov," %11.3e",varpij[i][j][(int)age]);
                 fprintf(ficresprobcor," %11.3e",varpij[i][j][(int) age]/sqrt(varpij[i][i][(int) age])/sqrt(varpij[j][j][(int)age]));
               }
             }
           }/* end of loop for state */
         } /* end of loop for age */
         free_vector(gp,1,(nlstate+ndeath)*(nlstate+ndeath));
         free_vector(gm,1,(nlstate+ndeath)*(nlstate+ndeath));
         free_matrix(trgradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
         free_matrix(gradg,1,(nlstate+ndeath)*(nlstate+ndeath),1,npar);
         
         /* Confidence intervalle of pij  */
         /*
           fprintf(ficgp,"\nunset parametric;unset label");
           fprintf(ficgp,"\nset log y;unset log x; set xlabel \"Age\";set ylabel \"probability (year-1)\"");
           fprintf(ficgp,"\nset ter png small\nset size 0.65,0.65");
           fprintf(fichtm,"\n<br>Probability with  confidence intervals expressed in year<sup>-1</sup> :<a href=\"pijgr%s.png\">pijgr%s.png</A>, ",optionfilefiname,optionfilefiname);
           fprintf(fichtm,"\n<br><img src=\"pijgr%s.png\"> ",optionfilefiname);
           fprintf(ficgp,"\nset out \"pijgr%s.png\"",optionfilefiname);
           fprintf(ficgp,"\nplot \"%s\" every :::%d::%d u 1:2 \"\%%lf",k1,k2,xfilevarprob);
         */
   
         /* Drawing ellipsoids of confidence of two variables p(k1-l1,k2-l2)*/
         first1=1;first2=2;
         for (k2=1; k2<=(nlstate);k2++){
           for (l2=1; l2<=(nlstate+ndeath);l2++){ 
             if(l2==k2) continue;
             j=(k2-1)*(nlstate+ndeath)+l2;
             for (k1=1; k1<=(nlstate);k1++){
               for (l1=1; l1<=(nlstate+ndeath);l1++){ 
                 if(l1==k1) continue;
                 i=(k1-1)*(nlstate+ndeath)+l1;
                 if(i<=j) continue;
                 for (age=bage; age<=fage; age ++){ 
                   if ((int)age %5==0){
                     v1=varpij[i][i][(int)age]/stepm*YEARM/stepm*YEARM;
                     v2=varpij[j][j][(int)age]/stepm*YEARM/stepm*YEARM;
                     cv12=varpij[i][j][(int)age]/stepm*YEARM/stepm*YEARM;
                     mu1=mu[i][(int) age]/stepm*YEARM ;
                     mu2=mu[j][(int) age]/stepm*YEARM;
                     c12=cv12/sqrt(v1*v2);
                     /* Computing eigen value of matrix of covariance */
                     lc1=((v1+v2)+sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                     lc2=((v1+v2)-sqrt((v1+v2)*(v1+v2) - 4*(v1*v2-cv12*cv12)))/2.;
                     if ((lc2 <0) || (lc1 <0) ){
                       if(first2==1){
                         first1=0;
                       printf("Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS. See log file for details...\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);
                       }
                       fprintf(ficlog,"Strange: j1=%d One eigen value of 2x2 matrix of covariance is negative, lc1=%11.3e, lc2=%11.3e, v1=%11.3e, v2=%11.3e, cv12=%11.3e.\n It means that the matrix was not well estimated (varpij), for i=%2d, j=%2d, age=%4d .\n See files %s and %s. Probably WRONG RESULTS.\n", j1, lc1, lc2, v1, v2, cv12, i, j, (int)age,fileresprobcov, fileresprobcor);fflush(ficlog);
                       /* lc1=fabs(lc1); */ /* If we want to have them positive */
                       /* lc2=fabs(lc2); */
                     }
   
                     /* Eigen vectors */
                     v11=(1./sqrt(1+(v1-lc1)*(v1-lc1)/cv12/cv12));
                     /*v21=sqrt(1.-v11*v11); *//* error */
                     v21=(lc1-v1)/cv12*v11;
                     v12=-v21;
                     v22=v11;
                     tnalp=v21/v11;
                     if(first1==1){
                       first1=0;
                       printf("%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tang %.3f\nOthers in log...\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                     }
                     fprintf(ficlog,"%d %d%d-%d%d mu %.4e %.4e Var %.4e %.4e cor %.3f cov %.4e Eig %.3e %.3e 1stv %.3f %.3f tan %.3f\n",(int) age,k1,l1,k2,l2,mu1,mu2,v1,v2,c12,cv12,lc1,lc2,v11,v21,tnalp);
                     /*printf(fignu*/
                     /* mu1+ v11*lc1*cost + v12*lc2*sin(t) */
                     /* mu2+ v21*lc1*cost + v22*lc2*sin(t) */
                     if(first==1){
                       first=0;
                       fprintf(ficgp,"\n# Ellipsoids of confidence\n#\n");
                       fprintf(ficgp,"\nset parametric;unset label");
                       fprintf(ficgp,"\nset log y;set log x; set xlabel \"p%1d%1d (year-1)\";set ylabel \"p%1d%1d (year-1)\"",k1,l1,k2,l2);
                       fprintf(ficgp,"\nset ter svg size 640, 480");
                       fprintf(fichtmcov,"\n<br>Ellipsoids of confidence cov(p%1d%1d,p%1d%1d) expressed in year<sup>-1</sup>\
    :<a href=\"%s_%d%1d%1d-%1d%1d.svg\">\
   %s_%d%1d%1d-%1d%1d.svg</A>, ",k1,l1,k2,l2,\
                               subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2,\
                               subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                       fprintf(fichtmcov,"\n<br><img src=\"%s_%d%1d%1d-%1d%1d.svg\"> ",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                       fprintf(fichtmcov,"\n<br> Correlation at age %d (%.3f),",(int) age, c12);
                       fprintf(ficgp,"\nset out \"%s_%d%1d%1d-%1d%1d.svg\"",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                       fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                       fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                       fprintf(ficgp,"\nplot [-pi:pi] %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\
                               mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\
                               mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                     }else{
                       first=0;
                       fprintf(fichtmcov," %d (%.3f),",(int) age, c12);
                       fprintf(ficgp,"\n# Age %d, p%1d%1d - p%1d%1d",(int) age, k1,l1,k2,l2);
                       fprintf(ficgp,"\nset label \"%d\" at %11.3e,%11.3e center",(int) age, mu1,mu2);
                       fprintf(ficgp,"\nreplot %11.3e+ %.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)), %11.3e +%.3f*(%11.3e*%11.3e*cos(t)+%11.3e*%11.3e*sin(t)) not",\
                               mu1,std,v11,sqrt(lc1),v12,sqrt(lc2),\
                               mu2,std,v21,sqrt(lc1),v22,sqrt(lc2));
                     }/* if first */
                   } /* age mod 5 */
                 } /* end loop age */
                 fprintf(ficgp,"\nset out;\nset out \"%s_%d%1d%1d-%1d%1d.svg\";replot;set out;",subdirf2(optionfilefiname,"VARPIJGR_"), j1,k1,l1,k2,l2);
                 first=1;
               } /*l12 */
             } /* k12 */
           } /*l1 */
         }/* k1 */
         /* } */ /* loop covariates */
     }
     free_ma3x(varpij,1,nlstate,1,nlstate+ndeath,(int) bage, (int)fage);
     free_matrix(mu,1,(nlstate+ndeath)*(nlstate+ndeath),(int) bage, (int)fage);
     free_matrix(doldm,1,(nlstate)*(nlstate+ndeath),1,(nlstate)*(nlstate+ndeath));
     free_matrix(dnewm,1,(nlstate)*(nlstate+ndeath),1,npar);
     free_vector(xp,1,npar);
     fclose(ficresprob);
     fclose(ficresprobcov);
     fclose(ficresprobcor);
     fflush(ficgp);
     fflush(fichtmcov);
   }
   
   
   /******************* Printing html file ***********/
   void printinghtml(char fileresu[], char title[], char datafile[], int firstpass, \
                     int lastpass, int stepm, int weightopt, char model[],\
                     int imx,int jmin, int jmax, double jmeanint,char rfileres[],\
                     int popforecast, int estepm ,\
                     double jprev1, double mprev1,double anprev1, \
                     double jprev2, double mprev2,double anprev2){
     int jj1, k1, i1, cpt;
   
      fprintf(fichtm,"<ul><li><a href='#firstorder'>Result files (first order: no variance)</a>\n \
      <li><a href='#secondorder'>Result files (second order (variance)</a>\n \
   </ul>");
      fprintf(fichtm,"<ul><li><h4><a name='firstorder'>Result files (first order: no variance)</a></h4>\n \
    - Observed prevalence in each state (during the period defined between %.lf/%.lf/%.lf and %.lf/%.lf/%.lf): <a href=\"%s\">%s</a> <br>\n ",
              jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,subdirf2(fileresu,"P_"),subdirf2(fileresu,"P_"));
      fprintf(fichtm,"\
    - Estimated transition probabilities over %d (stepm) months: <a href=\"%s\">%s</a><br>\n ",
              stepm,subdirf2(fileresu,"PIJ_"),subdirf2(fileresu,"PIJ_"));
      fprintf(fichtm,"\
    - Period (stable) prevalence in each health state: <a href=\"%s\">%s</a> <br>\n",
              subdirf2(fileresu,"PL_"),subdirf2(fileresu,"PL_"));
      fprintf(fichtm,"\
    - (a) Life expectancies by health status at initial age, ei. (b) health expectancies by health status at initial age, eij . If one or more covariates are included, specific tables for each value of the covariate are output in sequences within the same file (estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n",
              estepm,subdirf2(fileresu,"E_"),subdirf2(fileresu,"E_"));
      fprintf(fichtm,"\
    - Population projections by age and states: \
      <a href=\"%s\">%s</a> <br>\n</li>", subdirf2(fileresu,"F_"),subdirf2(fileresu,"F_"));
   
   fprintf(fichtm," \n<ul><li><b>Graphs</b></li><p>");
   
    m=pow(2,cptcoveff);
    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
   
    jj1=0;
    for(k1=1; k1<=m;k1++){
      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
        jj1++;
        if (cptcovn > 0) {
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
          for (cpt=1; cpt<=cptcoveff;cpt++){ 
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);
            printf(" V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);fflush(stdout);
          }
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
        }
        /* aij, bij */
        fprintf(fichtm,"<br>- Logit model, for example: logit(pij)=log(pij/pii)= aij+ bij age + V1 age + etc. as a function of age: <a href=\"%s_%d-1.svg\">%s_%d-1.svg</a><br> \
   <img src=\"%s_%d-1.svg\">",subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);
        /* Pij */
        fprintf(fichtm,"<br>\n- Pij or conditional probabilities to be observed in state j being in state i, %d (stepm) months before: <a href=\"%s_%d-2.svg\">%s_%d-2.svg</a><br> \
   <img src=\"%s_%d-2.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1);     
        /* Quasi-incidences */
        fprintf(fichtm,"<br>\n- Iij or Conditional probabilities to be observed in state j being in state i %d (stepm) months\
    before but expressed in per year i.e. quasi incidences if stepm is small and probabilities too,\
    incidence (rates) are the limit when h tends to zero of the ratio of the probability hPij \
   divided by h: hPij/h : <a href=\"%s_%d-3.svg\">%s_%d-3.svg</a><br> \
   <img src=\"%s_%d-3.svg\">",stepm,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1,subdirf2(optionfilefiname,"PE_"),jj1); 
        /* Survival functions (period) in state j */
        for(cpt=1; cpt<=nlstate;cpt++){
          fprintf(fichtm,"<br>\n- Survival functions in state %d. Or probability to survive in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
   <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1,subdirf2(optionfilefiname,"LIJ_"),cpt,jj1);
        }
        /* State specific survival functions (period) */
        for(cpt=1; cpt<=nlstate;cpt++){
          fprintf(fichtm,"<br>\n- Survival functions from state %d in each live state and total.\
    Or probability to survive in various states (1 to %d) being in state %d at different ages.\
    <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> <img src=\"%s_%d-%d.svg\">", cpt, nlstate, cpt, subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1,subdirf2(optionfilefiname,"LIJT_"),cpt,jj1);
        }
        /* Period (stable) prevalence in each health state */
        for(cpt=1; cpt<=nlstate;cpt++){
          fprintf(fichtm,"<br>\n- Convergence to period (stable) prevalence in state %d. Or probability to be in state %d being in state (1 to %d) at different ages. <a href=\"%s%d_%d.svg\">%s%d_%d.svg</a><br> \
   <img src=\"%s_%d-%d.svg\">", cpt, cpt, nlstate, subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1,subdirf2(optionfilefiname,"P_"),cpt,jj1);
        }
        for(cpt=1; cpt<=nlstate;cpt++) {
          fprintf(fichtm,"\n<br>- Life expectancy by health state (%d) at initial age and its decomposition into health expectancies in each alive state (1 to %d) (or area under each survival functions): <a href=\"%s_%d%d.svg\">%s_%d%d.svg</a> <br> \
   <img src=\"%s_%d%d.svg\">",cpt,nlstate,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1,subdirf2(optionfilefiname,"EXP_"),cpt,jj1);
        }
      /* } /\* end i1 *\/ */
    }/* End k1 */
    fprintf(fichtm,"</ul>");
   
    fprintf(fichtm,"\
   \n<br><li><h4> <a name='secondorder'>Result files (second order: variances)</a></h4>\n\
    - Parameter file with estimated parameters and covariance matrix: <a href=\"%s\">%s</a> <br> \
    - 95%% confidence intervals and Wald tests of the estimated parameters are in the log file if optimization has been done (mle != 0).<br> \
   But because parameters are usually highly correlated (a higher incidence of disability \
   and a higher incidence of recovery can give very close observed transition) it might \
   be very useful to look not only at linear confidence intervals estimated from the \
   variances but at the covariance matrix. And instead of looking at the estimated coefficients \
   (parameters) of the logistic regression, it might be more meaningful to visualize the \
   covariance matrix of the one-step probabilities. \
   See page 'Matrix of variance-covariance of one-step probabilities' below. \n", rfileres,rfileres);
   
    fprintf(fichtm," - Standard deviation of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileresu,"PROB_"),subdirf2(fileresu,"PROB_"));
    fprintf(fichtm,"\
    - Variance-covariance of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileresu,"PROBCOV_"),subdirf2(fileresu,"PROBCOV_"));
   
    fprintf(fichtm,"\
    - Correlation matrix of one-step probabilities: <a href=\"%s\">%s</a> <br>\n",
            subdirf2(fileresu,"PROBCOR_"),subdirf2(fileresu,"PROBCOR_"));
    fprintf(fichtm,"\
    - Variances and covariances of health expectancies by age and <b>initial health status</b> (cov(e<sup>ij</sup>,e<sup>kl</sup>)(estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n</li>",
              estepm,subdirf2(fileresu,"CVE_"),subdirf2(fileresu,"CVE_"));
    fprintf(fichtm,"\
    - (a) Health expectancies by health status at initial age (e<sup>ij</sup>) and standard errors (in parentheses) (b) life expectancies and standard errors (e<sup>i.</sup>=e<sup>i1</sup>+e<sup>i2</sup>+...)(estepm=%2d months): \
      <a href=\"%s\">%s</a> <br>\n</li>",
              estepm,subdirf2(fileresu,"STDE_"),subdirf2(fileresu,"STDE_"));
    fprintf(fichtm,"\
    - Variances and covariances of health expectancies by age. Status (i) based health expectancies (in state j), e<sup>ij</sup> are weighted by the period prevalences in each state i (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a><br>\n",
            estepm, subdirf2(fileresu,"V_"),subdirf2(fileresu,"V_"));
    fprintf(fichtm,"\
    - Total life expectancy and total health expectancies to be spent in each health state e<sup>.j</sup> with their standard errors (if popbased=1, an additional computation is done using the cross-sectional prevalences, i.e population based) (estepm=%d months): <a href=\"%s\">%s</a> <br>\n",
            estepm, subdirf2(fileresu,"T_"),subdirf2(fileresu,"T_"));
    fprintf(fichtm,"\
    - Standard deviation of period (stable) prevalences: <a href=\"%s\">%s</a> <br>\n",\
            subdirf2(fileresu,"VPL_"),subdirf2(fileresu,"VPL_"));
   
   /*  if(popforecast==1) fprintf(fichtm,"\n */
   /*  - Prevalences forecasting: <a href=\"f%s\">f%s</a> <br>\n */
   /*  - Population forecasting (if popforecast=1): <a href=\"pop%s\">pop%s</a> <br>\n */
   /*      <br>",fileres,fileres,fileres,fileres); */
   /*  else  */
   /*    fprintf(fichtm,"\n No population forecast: popforecast = %d (instead of 1) or stepm = %d (instead of 1) or model=%s (instead of .)<br><br></li>\n",popforecast, stepm, model); */
    fflush(fichtm);
    fprintf(fichtm," <ul><li><b>Graphs</b></li><p>");
   
    m=pow(2,cptcoveff);
    if (cptcovn < 1) {m=1;ncodemax[1]=1;}
   
    jj1=0;
    for(k1=1; k1<=m;k1++){
      /* for(i1=1; i1<=ncodemax[k1];i1++){ */
        jj1++;
        if (cptcovn > 0) {
          fprintf(fichtm,"<hr  size=\"2\" color=\"#EC5E5E\">************ Results for covariates");
          for (cpt=1; cpt<=cptcoveff;cpt++) 
            fprintf(fichtm," V%d=%d ",Tvaraff[cpt],nbcode[Tvaraff[cpt]][codtabm(jj1,cpt)]);
          fprintf(fichtm," ************\n<hr size=\"2\" color=\"#EC5E5E\">");
        }
        for(cpt=1; cpt<=nlstate;cpt++) {
          fprintf(fichtm,"<br>- Observed (cross-sectional) and period (incidence based) \
   prevalence (with 95%% confidence interval) in state (%d): <a href=\"%s_%d%d.svg\"> %s_%d-%d.svg <br>\
   <img src=\"%s_%d-%d.svg\">",cpt,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1,subdirf2(optionfilefiname,"V_"),cpt,jj1);  
        }
        fprintf(fichtm,"\n<br>- Total life expectancy by age and \
   health expectancies in states (1) and (2). If popbased=1 the smooth (due to the model) \
   true period expectancies (those weighted with period prevalences are also\
    drawn in addition to the population based expectancies computed using\
    observed and cahotic prevalences:  <a href=\"%s_%d.svg\">%s_%d.svg<br>\
   <img src=\"%s_%d.svg\">",subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1,subdirf2(optionfilefiname,"E_"),jj1);
      /* } /\* end i1 *\/ */
    }/* End k1 */
    fprintf(fichtm,"</ul>");
    fflush(fichtm);
   }
   
   /******************* Gnuplot file **************/
   void printinggnuplot(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
   
     char dirfileres[132],optfileres[132];
     int cpt=0,k1=0,i=0,k=0,j=0,jk=0,k2=0,k3=0,ij=0,l=0;
     int ng=0;
     int vpopbased;
   /*   if((ficgp=fopen(optionfilegnuplot,"a"))==NULL) { */
   /*     printf("Problem with file %s",optionfilegnuplot); */
   /*     fprintf(ficlog,"Problem with file %s",optionfilegnuplot); */
   /*   } */
   
     /*#ifdef windows */
     fprintf(ficgp,"cd \"%s\" \n",pathc);
       /*#endif */
     m=pow(2,cptcoveff);
   
     /* Projected Prevalences */
   /* plot "NAGI0w_V1V2_monthlyb2b-proj/F_NAGI0w_V1V2_monthlyb2b-proj.txt" u 6:((($1 == 1) && ($2==0) && ($3==2) &&($4==0))? $7/(1-$13):1/0) t 'p11' w line */
   /* replot ""  u 6:((($1 == 1) && ($2==0) && ($3==2) &&($4==0))? $8/(1-$14):1/0) t 'p21' w line */
   /* replot ""  u 6:((($1 == 1) && ($2==0) && ($3==2) &&($4==0)&&($9!=0))? $9/(1-$15):1/0) t 'p.1' w line */
   
     /* Contribution to likelihood */
     /* Plot the probability implied in the likelihood */
       fprintf(ficgp,"\n# Contributions to the Likelihood, mle >=1. For mle=4 no interpolation, pure matrix products.\n#\n");
       fprintf(ficgp,"\n set log y; unset log x;set xlabel \"Age\"; set ylabel \"Likelihood (-2Log(L))\";");
       /* fprintf(ficgp,"\nset ter svg size 640, 480"); */ /* Too big for svg */
       fprintf(ficgp,"\nset ter pngcairo size 640, 480");
   /* nice for mle=4 plot by number of matrix products.
      replot  "rrtest1/toto.txt" u 2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with point lc 1 */
   /* replot exp(p1+p2*x)/(1+exp(p1+p2*x)+exp(p3+p4*x)+exp(p5+p6*x)) t "p12(x)"  */
       /* fprintf(ficgp,"\nset out \"%s.svg\";",subdirf2(optionfilefiname,"ILK_")); */
       fprintf(ficgp,"\nset out \"%s-dest.png\";",subdirf2(optionfilefiname,"ILK_"));
       fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$12):5 t \"All sample, transitions colored by destination\" with dots lc variable; set out;\n",subdirf(fileresilk));
       fprintf(ficgp,"\nset out \"%s-ori.png\";",subdirf2(optionfilefiname,"ILK_"));
       fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$12):4 t \"All sample, transitions colored by origin\" with dots lc variable; set out;\n\n",subdirf(fileresilk));
       for (i=1; i<= nlstate ; i ++) {
         fprintf(ficgp,"\nset out \"%s-p%dj.png\";set ylabel \"Probability for each individual/wave\";",subdirf2(optionfilefiname,"ILK_"),i);
         fprintf(ficgp,"unset log;\n# plot weighted, mean weight should have point size of 0.5\n plot  \"%s\"",subdirf(fileresilk));
         fprintf(ficgp,"  u  2:($4 == %d && $5==%d ? $9 : 1/0):($11/4.):5 t \"p%d%d\" with points pointtype 7 ps variable lc variable \\\n",i,1,i,1);
         for (j=2; j<= nlstate+ndeath ; j ++) {
           fprintf(ficgp,",\\\n \"\" u  2:($4 == %d && $5==%d ? $9 : 1/0):($11/4.):5 t \"p%d%d\" with points pointtype 7 ps variable lc variable ",i,j,i,j);
         }
         fprintf(ficgp,";\nset out; unset ylabel;\n"); 
       }
       /* unset log; plot  "rrtest1_sorted_4/ILK_rrtest1_sorted_4.txt" u  2:($4 == 1 && $5==2 ? $9 : 1/0):5 t "p12" with points lc variable */              
       /* fprintf(ficgp,"\nset log y;plot  \"%s\" u 2:(-$11):3 t \"All sample, all transitions\" with dots lc variable",subdirf(fileresilk)); */
       /* fprintf(ficgp,"\nreplot  \"%s\" u 2:($3 <= 3 ? -$11 : 1/0):3 t \"First 3 individuals\" with line lc variable", subdirf(fileresilk)); */
       fprintf(ficgp,"\nset out;unset log\n");
       /* fprintf(ficgp,"\nset out \"%s.svg\"; replot; set out; # bug gnuplot",subdirf2(optionfilefiname,"ILK_")); */
   
     strcpy(dirfileres,optionfilefiname);
     strcpy(optfileres,"vpl");
    /* 1eme*/
     fprintf(ficgp,"\n# 1st: Period (stable) prevalence with CI: 'VPL_' files\n");
     for (cpt=1; cpt<= nlstate ; cpt ++) {
       for (k1=1; k1<= m ; k1 ++) { /* plot [100000000000000000000:-100000000000000000000] "mysbiaspar/vplrmysbiaspar.txt to check */
        fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"V_"),cpt,k1);
        fprintf(ficgp,"\n#set out \"V_%s_%d-%d.svg\" \n",optionfilefiname,cpt,k1);
        fprintf(ficgp,"set xlabel \"Age\" \n\
   set ylabel \"Probability\" \n\
   set ter svg size 640, 480\n\
   plot [%.f:%.f] \"%s\" every :::%d::%d u 1:2 \"%%lf",ageminpar,fage,subdirf2(fileresu,"VPL_"),k1-1,k1-1);
   
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
          else        fprintf(ficgp," %%*lf (%%*lf)");
        }
        fprintf(ficgp,"\" t\"Period (stable) prevalence\" w l lt 0,\"%s\" every :::%d::%d u 1:($2+1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1);
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
          else fprintf(ficgp," %%*lf (%%*lf)");
        } 
        fprintf(ficgp,"\" t\"95%% CI\" w l lt 1,\"%s\" every :::%d::%d u 1:($2-1.96*$3) \"%%lf",subdirf2(fileresu,"VPL_"),k1-1,k1-1); 
        for (i=1; i<= nlstate ; i ++) {
          if (i==cpt) fprintf(ficgp," %%lf (%%lf)");
          else fprintf(ficgp," %%*lf (%%*lf)");
        }  
        fprintf(ficgp,"\" t\"\" w l lt 1,\"%s\" every :::%d::%d u 1:($%d) t\"Observed prevalence \" w l lt 2",subdirf2(fileresu,"P_"),k1-1,k1-1,2+4*(cpt-1));
        fprintf(ficgp,"\nset out \n");
       } /* k1 */
     } /* cpt */
     /*2 eme*/
     fprintf(ficgp,"\n# 2nd: Total life expectancy with CI: 't' files\n");
     for (k1=1; k1<= m ; k1 ++) { 
       fprintf(ficgp,"\nset out \"%s_%d.svg\" \n",subdirf2(optionfilefiname,"E_"),k1);
       for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
         if(vpopbased==0)
           fprintf(ficgp,"set ylabel \"Years\" \nset ter svg size 640, 480\nplot [%.f:%.f] ",ageminpar,fage);
         else
           fprintf(ficgp,"\nreplot ");
         for (i=1; i<= nlstate+1 ; i ++) {
           k=2*i;
           fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ?$4 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1, vpopbased);
           for (j=1; j<= nlstate+1 ; j ++) {
             if (j==i) fprintf(ficgp," %%lf (%%lf)");
             else fprintf(ficgp," %%*lf (%%*lf)");
           }   
           if (i== 1) fprintf(ficgp,"\" t\"TLE\" w l lt %d, \\\n",i);
           else fprintf(ficgp,"\" t\"LE in state (%d)\" w l lt %d, \\\n",i-1,i+1);
           fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4-$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
           for (j=1; j<= nlstate+1 ; j ++) {
             if (j==i) fprintf(ficgp," %%lf (%%lf)");
             else fprintf(ficgp," %%*lf (%%*lf)");
           }   
           fprintf(ficgp,"\" t\"\" w l lt 0,");
           fprintf(ficgp,"\"%s\" every :::%d::%d u 1:($2==%d && $4!=0 ? $4+$5*2 : 1/0) \"%%lf %%lf %%lf",subdirf2(fileresu,"T_"),k1-1,k1-1,vpopbased);
           for (j=1; j<= nlstate+1 ; j ++) {
             if (j==i) fprintf(ficgp," %%lf (%%lf)");
             else fprintf(ficgp," %%*lf (%%*lf)");
           }   
           if (i== (nlstate+1)) fprintf(ficgp,"\" t\"\" w l lt 0");
           else fprintf(ficgp,"\" t\"\" w l lt 0,\\\n");
         } /* state */
       } /* vpopbased */
       fprintf(ficgp,"\nset out;set out \"%s_%d.svg\"; replot; set out; \n",subdirf2(optionfilefiname,"E_"),k1); /* Buggy gnuplot */
     } /* k1 */
     /*3eme*/
     
     for (k1=1; k1<= m ; k1 ++) { 
       for (cpt=1; cpt<= nlstate ; cpt ++) {
         /*       k=2+nlstate*(2*cpt-2); */
         k=2+(nlstate+1)*(cpt-1);
         fprintf(ficgp,"\nset out \"%s_%d%d.svg\" \n",subdirf2(optionfilefiname,"EXP_"),cpt,k1);
         fprintf(ficgp,"set ter svg size 640, 480\n\
   plot [%.f:%.f] \"%s\" every :::%d::%d u 1:%d t \"e%d1\" w l",ageminpar,fage,subdirf2(fileresu,"E_"),k1-1,k1-1,k,cpt);
         /*fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d-2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
           for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
           fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
           fprintf(ficgp,",\"e%s\" every :::%d::%d u 1:($%d+2*$%d) \"\%%lf ",fileres,k1-1,k1-1,k,k+1);
           for (i=1; i<= nlstate*2 ; i ++) fprintf(ficgp,"\%%lf (\%%lf) ");
           fprintf(ficgp,"\" t \"e%d1\" w l",cpt);
           
         */
         for (i=1; i< nlstate ; i ++) {
           fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+i,cpt,i+1);
           /*      fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d%d\" w l",subdirf2(fileres,"e"),k1-1,k1-1,k+2*i,cpt,i+1);*/
           
         } 
         fprintf(ficgp," ,\"%s\" every :::%d::%d u 1:%d t \"e%d.\" w l",subdirf2(fileresu,"E_"),k1-1,k1-1,k+nlstate,cpt);
       }
     }
     
     /* Survival functions (period) from state i in state j by initial state i */
     for (k1=1; k1<= m ; k1 ++) { /* For each multivariate if any */
       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
         k=3;
         fprintf(ficgp,"\n#\n#\n# Survival functions in state j : 'lij' files, cov=%d state=%d",k1, cpt);
         fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJ_"),cpt,k1);
         fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
   set ter svg size 640, 480\n\
   unset log y\n\
   plot [%.f:%.f]  ", ageminpar, agemaxpar);
         for (i=1; i<= nlstate ; i ++){
           if(i==1)
             fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
           else
             fprintf(ficgp,", '' ");
           l=(nlstate+ndeath)*(i-1)+1;
           fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
           for (j=2; j<= nlstate+ndeath ; j ++)
             fprintf(ficgp,"+$%d",k+l+j-1);
           fprintf(ficgp,")) t \"l(%d,%d)\" w l",i,cpt);
         } /* nlstate */
         fprintf(ficgp,"\nset out\n");
       } /* end cpt state*/ 
     } /* end covariate */  
   
     /* Survival functions (period) from state i in state j by final state j */
     for (k1=1; k1<= m ; k1 ++) { /* For each covariate if any */
       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each inital state  */
         k=3;
         fprintf(ficgp,"\n#\n#\n# Survival functions in state j and all livestates from state i by final state j: 'lij' files, cov=%d state=%d",k1, cpt);
         fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"LIJT_"),cpt,k1);
         fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability to be alive\" \n\
   set ter svg size 640, 480\n\
   unset log y\n\
   plot [%.f:%.f]  ", ageminpar, agemaxpar);
         for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
           if(j==1)
             fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
           else
             fprintf(ficgp,", '' ");
           l=(nlstate+ndeath)*(cpt-1) +j;
           fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):($%d",k1,k+l);
           /* for (i=2; i<= nlstate+ndeath ; i ++) */
           /*   fprintf(ficgp,"+$%d",k+l+i-1); */
           fprintf(ficgp,") t \"l(%d,%d)\" w l",cpt,j);
         } /* nlstate */
         fprintf(ficgp,", '' ");
         fprintf(ficgp," u (($1==%d && (floor($2)%%5 == 0)) ? ($3):1/0):(",k1);
         for (j=1; j<= nlstate ; j ++){ /* Lived in state j */
           l=(nlstate+ndeath)*(cpt-1) +j;
           if(j < nlstate)
             fprintf(ficgp,"$%d +",k+l);
           else
             fprintf(ficgp,"$%d) t\"l(%d,.)\" w l",k+l,cpt);
         }
         fprintf(ficgp,"\nset out\n");
       } /* end cpt state*/ 
     } /* end covariate */  
   
     /* CV preval stable (period) for each covariate */
     for (k1=1; k1<= m ; k1 ++) { /* For each covariate if any */
       for (cpt=1; cpt<=nlstate ; cpt ++) { /* For each life state */
         k=3;
         fprintf(ficgp,"\n#\n#\n#CV preval stable (period): 'pij' files, cov=%d state=%d",k1, cpt);
         fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" \n",subdirf2(optionfilefiname,"P_"),cpt,k1);
         fprintf(ficgp,"set xlabel \"Age\" \nset ylabel \"Probability\" \n\
   set ter svg size 640, 480\n\
   unset log y\n\
   plot [%.f:%.f]  ", ageminpar, agemaxpar);
         for (i=1; i<= nlstate ; i ++){
           if(i==1)
             fprintf(ficgp,"\"%s\"",subdirf2(fileresu,"PIJ_"));
           else
             fprintf(ficgp,", '' ");
           l=(nlstate+ndeath)*(i-1)+1;
           fprintf(ficgp," u ($1==%d ? ($3):1/0):($%d/($%d",k1,k+l+(cpt-1),k+l);
           for (j=2; j<= nlstate ; j ++)
             fprintf(ficgp,"+$%d",k+l+j-1);
           fprintf(ficgp,")) t \"prev(%d,%d)\" w l",i,cpt);
         } /* nlstate */
         fprintf(ficgp,"\nset out\n");
       } /* end cpt state*/ 
     } /* end covariate */  
   
     /* proba elementaires */
     fprintf(ficgp,"\n##############\n#MLE estimated parameters\n#############\n");
     for(i=1,jk=1; i <=nlstate; i++){
       fprintf(ficgp,"# initial state %d\n",i);
       for(k=1; k <=(nlstate+ndeath); k++){
         if (k != i) {
           fprintf(ficgp,"#   current state %d\n",k);
           for(j=1; j <=ncovmodel; j++){
             fprintf(ficgp,"p%d=%f; ",jk,p[jk]);
             jk++; 
           }
           fprintf(ficgp,"\n");
         }
       }
      }
     fprintf(ficgp,"##############\n#\n");
   
     /*goto avoid;*/
     fprintf(ficgp,"\n##############\n#Graphics of probabilities or incidences\n#############\n");
     fprintf(ficgp,"# logi(p12/p11)=a12+b12*age+c12age*age+d12*V1+e12*V1*age\n");
     fprintf(ficgp,"# logi(p12/p11)=p1 +p2*age +p3*age*age+ p4*V1+ p5*V1*age\n");
     fprintf(ficgp,"# logi(p13/p11)=a13+b13*age+c13age*age+d13*V1+e13*V1*age\n");
     fprintf(ficgp,"# logi(p13/p11)=p6 +p7*age +p8*age*age+ p9*V1+ p10*V1*age\n");
     fprintf(ficgp,"# p12+p13+p14+p11=1=p11(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
     fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
     fprintf(ficgp,"# p11=1/(1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
     fprintf(ficgp,"#                      +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age)+...)\n");
     fprintf(ficgp,"# p12=exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)/\n");
     fprintf(ficgp,"#     (1+exp(a12+b12*age+c12age*age+d12*V1+e12*V1*age)\n");
     fprintf(ficgp,"#       +exp(a13+b13*age+c13age*age+d13*V1+e13*V1*age))\n");
     fprintf(ficgp,"#       +exp(a14+b14*age+c14age*age+d14*V1+e14*V1*age)+...)\n");
     fprintf(ficgp,"#\n");
      for(ng=1; ng<=3;ng++){ /* Number of graphics: first is logit, 2nd is probabilities, third is incidences per year*/
        fprintf(ficgp,"# ng=%d\n",ng);
        fprintf(ficgp,"#   jk=1 to 2^%d=%d\n",cptcoveff,m);
        for(jk=1; jk <=m; jk++) {
          fprintf(ficgp,"#    jk=%d\n",jk);
          fprintf(ficgp,"\nset out \"%s_%d-%d.svg\" ",subdirf2(optionfilefiname,"PE_"),jk,ng);
          fprintf(ficgp,"\nset ter svg size 640, 480 ");
          if (ng==1){
            fprintf(ficgp,"\nset ylabel \"Value of the logit of the model\"\n"); /* exp(a12+b12*x) could be nice */
            fprintf(ficgp,"\nunset log y");
          }else if (ng==2){
            fprintf(ficgp,"\nset ylabel \"Probability\"\n");
            fprintf(ficgp,"\nset log y");
          }else if (ng==3){
            fprintf(ficgp,"\nset ylabel \"Quasi-incidence per year\"\n");
            fprintf(ficgp,"\nset log y");
          }else
            fprintf(ficgp,"\nunset title ");
          fprintf(ficgp,"\nplot  [%.f:%.f] ",ageminpar,agemaxpar);
          i=1;
          for(k2=1; k2<=nlstate; k2++) {
            k3=i;
            for(k=1; k<=(nlstate+ndeath); k++) {
              if (k != k2){
                switch( ng) {
                case 1:
                  if(nagesqr==0)
                    fprintf(ficgp," p%d+p%d*x",i,i+1);
                  else /* nagesqr =1 */
                    fprintf(ficgp," p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                  break;
                case 2: /* ng=2 */
                  if(nagesqr==0)
                    fprintf(ficgp," exp(p%d+p%d*x",i,i+1);
                  else /* nagesqr =1 */
                      fprintf(ficgp," exp(p%d+p%d*x+p%d*x*x",i,i+1,i+1+nagesqr);
                  break;
                case 3:
                  if(nagesqr==0)
                    fprintf(ficgp," %f*exp(p%d+p%d*x",YEARM/stepm,i,i+1);
                  else /* nagesqr =1 */
                    fprintf(ficgp," %f*exp(p%d+p%d*x+p%d*x*x",YEARM/stepm,i,i+1,i+1+nagesqr);
                  break;
                }
                ij=1;/* To be checked else nbcode[0][0] wrong */
                for(j=3; j <=ncovmodel-nagesqr; j++) {
                  /* printf("Tage[%d]=%d, j=%d\n", ij, Tage[ij], j); */
                  if(ij <=cptcovage) { /* Bug valgrind */
                    if((j-2)==Tage[ij]) { /* Bug valgrind */
                      fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                      /* fprintf(ficgp,"+p%d*%d*x",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                      ij++;
                    }
                  }
                  else
                    fprintf(ficgp,"+p%d*%d",i+j+nagesqr-1,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                }
                if(ng != 1){
                  fprintf(ficgp,")/(1");
                
                  for(k1=1; k1 <=nlstate; k1++){ 
                    if(nagesqr==0)
                      fprintf(ficgp,"+exp(p%d+p%d*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1);
                    else /* nagesqr =1 */
                      fprintf(ficgp,"+exp(p%d+p%d*x+p%d*x*x",k3+(k1-1)*ncovmodel,k3+(k1-1)*ncovmodel+1,k3+(k1-1)*ncovmodel+1+nagesqr);
                    
                    ij=1;
                    for(j=3; j <=ncovmodel-nagesqr; j++){
                      if(ij <=cptcovage) { /* Bug valgrind */
                        if((j-2)==Tage[ij]) { /* Bug valgrind */
                          fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                          /* fprintf(ficgp,"+p%d*%d*x",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,Tvar[j-2])]); */
                          ij++;
                        }
                      }
                      else
                        fprintf(ficgp,"+p%d*%d",k3+(k1-1)*ncovmodel+1+j-2+nagesqr,nbcode[Tvar[j-2]][codtabm(jk,j-2)]);
                    }
                    fprintf(ficgp,")");
                  }
                  fprintf(ficgp,")");
                  if(ng ==2)
                    fprintf(ficgp," t \"p%d%d\" ", k2,k);
                  else /* ng= 3 */
                    fprintf(ficgp," t \"i%d%d\" ", k2,k);
                }else{ /* end ng <> 1 */
                  fprintf(ficgp," t \"logit(p%d%d)\" ", k2,k);
                }
                if ((k+k2)!= (nlstate*2+ndeath)) fprintf(ficgp,",");
                i=i+ncovmodel;
              }
            } /* end k */
          } /* end k2 */
          fprintf(ficgp,"\n set out\n");
        } /* end jk */
      } /* end ng */
    /* avoid: */
      fflush(ficgp); 
   }  /* end gnuplot */
   
   
   /*************** Moving average **************/
   int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav){
   
     int i, cpt, cptcod;
     int modcovmax =1;
     int mobilavrange, mob;
     double age;
   
     modcovmax=2*cptcoveff;/* Max number of modalities. We suppose 
                              a covariate has 2 modalities */
     if (cptcovn<1) modcovmax=1; /* At least 1 pass */
   
     if(mobilav==1||mobilav ==3 ||mobilav==5 ||mobilav== 7){
       if(mobilav==1) mobilavrange=5; /* default */
       else mobilavrange=mobilav;
       for (age=bage; age<=fage; age++)
         for (i=1; i<=nlstate;i++)
           for (cptcod=1;cptcod<=modcovmax;cptcod++)
             mobaverage[(int)age][i][cptcod]=probs[(int)age][i][cptcod];
       /* We keep the original values on the extreme ages bage, fage and for 
          fage+1 and bage-1 we use a 3 terms moving average; for fage+2 bage+2
          we use a 5 terms etc. until the borders are no more concerned. 
       */ 
       for (mob=3;mob <=mobilavrange;mob=mob+2){
         for (age=bage+(mob-1)/2; age<=fage-(mob-1)/2; age++){
           for (i=1; i<=nlstate;i++){
             for (cptcod=1;cptcod<=modcovmax;cptcod++){
               mobaverage[(int)age][i][cptcod] =probs[(int)age][i][cptcod];
                 for (cpt=1;cpt<=(mob-1)/2;cpt++){
                   mobaverage[(int)age][i][cptcod] +=probs[(int)age-cpt][i][cptcod];
                   mobaverage[(int)age][i][cptcod] +=probs[(int)age+cpt][i][cptcod];
                 }
               mobaverage[(int)age][i][cptcod]=mobaverage[(int)age][i][cptcod]/mob;
             }
           }
         }/* end age */
       }/* end mob */
     }else return -1;
     return 0;
   }/* End movingaverage */
   
   
   /************** Forecasting ******************/
   void prevforecast(char fileres[], double anproj1, double mproj1, double jproj1, double ageminpar, double agemax, double dateprev1, double dateprev2, int mobilav, double bage, double fage, int firstpass, int lastpass, double anproj2, double p[], int cptcoveff){
     /* proj1, year, month, day of starting projection 
        agemin, agemax range of age
        dateprev1 dateprev2 range of dates during which prevalence is computed
        anproj2 year of en of projection (same day and month as proj1).
     */
     int yearp, stepsize, hstepm, nhstepm, j, k, cptcod, i, h, i1;
     double agec; /* generic age */
     double agelim, ppij, yp,yp1,yp2,jprojmean,mprojmean,anprojmean;
     double *popeffectif,*popcount;
     double ***p3mat;
     double ***mobaverage;
     char fileresf[FILENAMELENGTH];
   
     agelim=AGESUP;
     prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
    
     strcpy(fileresf,"F_"); 
     strcat(fileresf,fileresu);
     if((ficresf=fopen(fileresf,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", fileresf);
       fprintf(ficlog,"Problem with forecast resultfile: %s\n", fileresf);
     }
     printf("Computing forecasting: result on file '%s' \n", fileresf);
     fprintf(ficlog,"Computing forecasting: result on file '%s' \n", fileresf);
   
     if (cptcoveff==0) ncodemax[cptcoveff]=1;
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     stepsize=(int) (stepm+YEARM-1)/YEARM;
     if (stepm<=12) stepsize=1;
     if(estepm < stepm){
       printf ("Problem %d lower than %d\n",estepm, stepm);
     }
     else  hstepm=estepm;   
   
     hstepm=hstepm/stepm; 
     yp1=modf(dateintmean,&yp);/* extracts integral of datemean in yp  and
                                  fractional in yp1 */
     anprojmean=yp;
     yp2=modf((yp1*12),&yp);
     mprojmean=yp;
     yp1=modf((yp2*30.5),&yp);
     jprojmean=yp;
     if(jprojmean==0) jprojmean=1;
     if(mprojmean==0) jprojmean=1;
   
     i1=cptcoveff;
     if (cptcovn < 1){i1=1;}
     
     fprintf(ficresf,"# Mean day of interviews %.lf/%.lf/%.lf (%.2f) between %.2f and %.2f \n",jprojmean,mprojmean,anprojmean,dateintmean,dateprev1,dateprev2); 
     
     fprintf(ficresf,"#****** Routine prevforecast **\n");
   
   /*            if (h==(int)(YEARM*yearp)){ */
     for(cptcov=1, k=0;cptcov<=i1;cptcov++){
       for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
         k=k+1;
         fprintf(ficresf,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficresf," V%d=%d, hpijx=probability over h years, hp.jx is weighted by observed prev ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
         }
         fprintf(ficresf,"******\n");
         fprintf(ficresf,"# Covariate valuofcovar yearproj age");
         for(j=1; j<=nlstate+ndeath;j++){ 
           for(i=1; i<=nlstate;i++)              
             fprintf(ficresf," p%d%d",i,j);
           fprintf(ficresf," p.%d",j);
         }
         for (yearp=0; yearp<=(anproj2-anproj1);yearp +=stepsize) { 
           fprintf(ficresf,"\n");
           fprintf(ficresf,"\n# Forecasting at date %.lf/%.lf/%.lf ",jproj1,mproj1,anproj1+yearp);   
   
           for (agec=fage; agec>=(ageminpar-1); agec--){ 
             nhstepm=(int) rint((agelim-agec)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agec,hstepm,p,nlstate,stepm,oldm,savm, k);  
           
             for (h=0; h<=nhstepm; h++){
               if (h*hstepm/YEARM*stepm ==yearp) {
                 fprintf(ficresf,"\n");
                 for(j=1;j<=cptcoveff;j++) 
                   fprintf(ficresf,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
                 fprintf(ficresf,"%.f %.f ",anproj1+yearp,agec+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 ppij=0.;
                 for(i=1; i<=nlstate;i++) {
                   if (mobilav==1) 
                     ppij=ppij+p3mat[i][j][h]*mobaverage[(int)agec][i][cptcod];
                   else {
                     ppij=ppij+p3mat[i][j][h]*probs[(int)(agec)][i][cptcod];
                   }
                   if (h*hstepm/YEARM*stepm== yearp) {
                     fprintf(ficresf," %.3f", p3mat[i][j][h]);
                   }
                 } /* end i */
                 if (h*hstepm/YEARM*stepm==yearp) {
                   fprintf(ficresf," %.3f", ppij);
                 }
               }/* end j */
             } /* end h */
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           } /* end agec */
         } /* end yearp */
       } /* end cptcod */
     } /* end  cptcov */
          
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     fclose(ficresf);
   }
   
   /************** Forecasting *****not tested NB*************/
   void populforecast(char fileres[], double anpyram,double mpyram,double jpyram,double ageminpar, double agemax,double dateprev1, double dateprev2, int mobilav, double agedeb, double fage, int popforecast, char popfile[], double anpyram1,double p[], int i2){
     
     int cpt, stepsize, hstepm, nhstepm, j,k,c, cptcod, i,h;
     int *popage;
     double calagedatem, agelim, kk1, kk2;
     double *popeffectif,*popcount;
     double ***p3mat,***tabpop,***tabpopprev;
     double ***mobaverage;
     char filerespop[FILENAMELENGTH];
   
     tabpop= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     tabpopprev= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     agelim=AGESUP;
     calagedatem=(anpyram+mpyram/12.+jpyram/365.-dateintmean)*YEARM;
     
     prevalence(probs, ageminpar, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
     
     
     strcpy(filerespop,"POP_"); 
     strcat(filerespop,fileresu);
     if((ficrespop=fopen(filerespop,"w"))==NULL) {
       printf("Problem with forecast resultfile: %s\n", filerespop);
       fprintf(ficlog,"Problem with forecast resultfile: %s\n", filerespop);
     }
     printf("Computing forecasting: result on file '%s' \n", filerespop);
     fprintf(ficlog,"Computing forecasting: result on file '%s' \n", filerespop);
   
     if (cptcoveff==0) ncodemax[cptcoveff]=1;
   
     if (mobilav!=0) {
       mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       if (movingaverage(probs, ageminpar, fage, mobaverage,mobilav)!=0){
         fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
         printf(" Error in movingaverage mobilav=%d\n",mobilav);
       }
     }
   
     stepsize=(int) (stepm+YEARM-1)/YEARM;
     if (stepm<=12) stepsize=1;
     
     agelim=AGESUP;
     
     hstepm=1;
     hstepm=hstepm/stepm; 
     
     if (popforecast==1) {
       if((ficpop=fopen(popfile,"r"))==NULL) {
         printf("Problem with population file : %s\n",popfile);exit(0);
         fprintf(ficlog,"Problem with population file : %s\n",popfile);exit(0);
       } 
       popage=ivector(0,AGESUP);
       popeffectif=vector(0,AGESUP);
       popcount=vector(0,AGESUP);
       
       i=1;   
       while ((c=fscanf(ficpop,"%d %lf\n",&popage[i],&popcount[i])) != EOF) i=i+1;
      
       imx=i;
       for (i=1; i<imx;i++) popeffectif[popage[i]]=popcount[i];
     }
   
     for(cptcov=1,k=0;cptcov<=i2;cptcov++){
      for(cptcod=1;cptcod<=ncodemax[cptcoveff];cptcod++){
         k=k+1;
         fprintf(ficrespop,"\n#******");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficrespop," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
         }
         fprintf(ficrespop,"******\n");
         fprintf(ficrespop,"# Age");
         for(j=1; j<=nlstate+ndeath;j++) fprintf(ficrespop," P.%d",j);
         if (popforecast==1)  fprintf(ficrespop," [Population]");
         
         for (cpt=0; cpt<=0;cpt++) { 
           fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);   
           
           for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){ 
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
           
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedatem+YEARM*cpt)) {
                 fprintf(ficrespop,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   if (mobilav==1) 
                     kk1=kk1+p3mat[i][j][h]*mobaverage[(int)agedeb+1][i][cptcod];
                   else {
                     kk1=kk1+p3mat[i][j][h]*probs[(int)(agedeb+1)][i][cptcod];
                   }
                 }
                 if (h==(int)(calagedatem+12*cpt)){
                   tabpop[(int)(agedeb)][j][cptcod]=kk1;
                     /*fprintf(ficrespop," %.3f", kk1);
                       if (popforecast==1) fprintf(ficrespop," [%.f]", kk1*popeffectif[(int)agedeb+1]);*/
                 }
               }
               for(i=1; i<=nlstate;i++){
                 kk1=0.;
                   for(j=1; j<=nlstate;j++){
                     kk1= kk1+tabpop[(int)(agedeb)][j][cptcod]; 
                   }
                     tabpopprev[(int)(agedeb)][i][cptcod]=tabpop[(int)(agedeb)][i][cptcod]/kk1*popeffectif[(int)(agedeb+(calagedatem+12*cpt)*hstepm/YEARM*stepm-1)];
               }
   
               if (h==(int)(calagedatem+12*cpt)) for(j=1; j<=nlstate;j++) 
                 fprintf(ficrespop," %15.2f",tabpopprev[(int)(agedeb+1)][j][cptcod]);
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
    
     /******/
   
         for (cpt=1; cpt<=(anpyram1-anpyram);cpt++) { 
           fprintf(ficrespop,"\n\n# Forecasting at date %.lf/%.lf/%.lf ",jpyram,mpyram,anpyram+cpt);   
           for (agedeb=(fage-((int)calagedatem %12/12.)); agedeb>=(ageminpar-((int)calagedatem %12)/12.); agedeb--){ 
             nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); 
             nhstepm = nhstepm/hstepm; 
             
             p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
             oldm=oldms;savm=savms;
             hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
             for (h=0; h<=nhstepm; h++){
               if (h==(int) (calagedatem+YEARM*cpt)) {
                 fprintf(ficresf,"\n %3.f ",agedeb+h*hstepm/YEARM*stepm);
               } 
               for(j=1; j<=nlstate+ndeath;j++) {
                 kk1=0.;kk2=0;
                 for(i=1; i<=nlstate;i++) {              
                   kk1=kk1+p3mat[i][j][h]*tabpopprev[(int)agedeb+1][i][cptcod];    
                 }
                 if (h==(int)(calagedatem+12*cpt)) fprintf(ficresf," %15.2f", kk1);        
               }
             }
             free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           }
         }
      } 
     }
    
     if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
   
     if (popforecast==1) {
       free_ivector(popage,0,AGESUP);
       free_vector(popeffectif,0,AGESUP);
       free_vector(popcount,0,AGESUP);
     }
     free_ma3x(tabpop,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     free_ma3x(tabpopprev,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
     fclose(ficrespop);
   } /* End of popforecast */
   
   int fileappend(FILE *fichier, char *optionfich)
   {
     if((fichier=fopen(optionfich,"a"))==NULL) {
       printf("Problem with file: %s\n", optionfich);
       fprintf(ficlog,"Problem with file: %s\n", optionfich);
       return (0);
     }
     fflush(fichier);
     return (1);
   }
   
   
   /**************** function prwizard **********************/
   void prwizard(int ncovmodel, int nlstate, int ndeath,  char model[], FILE *ficparo)
   {
   
     /* Wizard to print covariance matrix template */
   
     char ca[32], cb[32];
     int i,j, k, li, lj, lk, ll, jj, npar, itimes;
     int numlinepar;
   
     printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     fprintf(ficparo,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
     for(i=1; i <=nlstate; i++){
       jj=0;
       for(j=1; j <=nlstate+ndeath; j++){
         if(j==i) continue;
         jj++;
         /*ca[0]= k+'a'-1;ca[1]='\0';*/
         printf("%1d%1d",i,j);
         fprintf(ficparo,"%1d%1d",i,j);
         for(k=1; k<=ncovmodel;k++){
           /*        printf(" %lf",param[i][j][k]); */
           /*        fprintf(ficparo," %lf",param[i][j][k]); */
           printf(" 0.");
           fprintf(ficparo," 0.");
         }
         printf("\n");
         fprintf(ficparo,"\n");
       }
     }
     printf("# Scales (for hessian or gradient estimation)\n");
     fprintf(ficparo,"# Scales (for hessian or gradient estimation)\n");
     npar= (nlstate+ndeath-1)*nlstate*ncovmodel; /* Number of parameters*/ 
     for(i=1; i <=nlstate; i++){
       jj=0;
       for(j=1; j <=nlstate+ndeath; j++){
         if(j==i) continue;
         jj++;
         fprintf(ficparo,"%1d%1d",i,j);
         printf("%1d%1d",i,j);
         fflush(stdout);
         for(k=1; k<=ncovmodel;k++){
           /*      printf(" %le",delti3[i][j][k]); */
           /*      fprintf(ficparo," %le",delti3[i][j][k]); */
           printf(" 0.");
           fprintf(ficparo," 0.");
         }
         numlinepar++;
         printf("\n");
         fprintf(ficparo,"\n");
       }
     }
     printf("# Covariance matrix\n");
   /* # 121 Var(a12)\n\ */
   /* # 122 Cov(b12,a12) Var(b12)\n\ */
   /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
   /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
   /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
   /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
   /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
   /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
     fflush(stdout);
     fprintf(ficparo,"# Covariance matrix\n");
     /* # 121 Var(a12)\n\ */
     /* # 122 Cov(b12,a12) Var(b12)\n\ */
     /* #   ...\n\ */
     /* # 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n" */
     
     for(itimes=1;itimes<=2;itimes++){
       jj=0;
       for(i=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath; j++){
           if(j==i) continue;
           for(k=1; k<=ncovmodel;k++){
             jj++;
             ca[0]= k+'a'-1;ca[1]='\0';
             if(itimes==1){
               printf("#%1d%1d%d",i,j,k);
               fprintf(ficparo,"#%1d%1d%d",i,j,k);
             }else{
               printf("%1d%1d%d",i,j,k);
               fprintf(ficparo,"%1d%1d%d",i,j,k);
               /*  printf(" %.5le",matcov[i][j]); */
             }
             ll=0;
             for(li=1;li <=nlstate; li++){
               for(lj=1;lj <=nlstate+ndeath; lj++){
                 if(lj==li) continue;
                 for(lk=1;lk<=ncovmodel;lk++){
                   ll++;
                   if(ll<=jj){
                     cb[0]= lk +'a'-1;cb[1]='\0';
                     if(ll<jj){
                       if(itimes==1){
                         printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                         fprintf(ficparo," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                       }else{
                         printf(" 0.");
                         fprintf(ficparo," 0.");
                       }
                     }else{
                       if(itimes==1){
                         printf(" Var(%s%1d%1d)",ca,i,j);
                         fprintf(ficparo," Var(%s%1d%1d)",ca,i,j);
                       }else{
                         printf(" 0.");
                         fprintf(ficparo," 0.");
                       }
                     }
                   }
                 } /* end lk */
               } /* end lj */
             } /* end li */
             printf("\n");
             fprintf(ficparo,"\n");
             numlinepar++;
           } /* end k*/
         } /*end j */
       } /* end i */
     } /* end itimes */
   
   } /* end of prwizard */
   /******************* Gompertz Likelihood ******************************/
   double gompertz(double x[])
   { 
     double A,B,L=0.0,sump=0.,num=0.;
     int i,n=0; /* n is the size of the sample */
   
     for (i=0;i<=imx-1 ; i++) {
       sump=sump+weight[i];
       /*    sump=sump+1;*/
       num=num+1;
     }
    
    
     /* for (i=0; i<=imx; i++) 
        if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
   
     for (i=1;i<=imx ; i++)
       {
         if (cens[i] == 1 && wav[i]>1)
           A=-x[1]/(x[2])*(exp(x[2]*(agecens[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)));
         
         if (cens[i] == 0 && wav[i]>1)
           A=-x[1]/(x[2])*(exp(x[2]*(agedc[i]-agegomp))-exp(x[2]*(ageexmed[i]-agegomp)))
                +log(x[1]/YEARM)+x[2]*(agedc[i]-agegomp)+log(YEARM);  
         
         /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
         if (wav[i] > 1 ) { /* ??? */
           L=L+A*weight[i];
           /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
         }
       }
   
    /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
    
     return -2*L*num/sump;
   }
   
   #ifdef GSL
   /******************* Gompertz_f Likelihood ******************************/
   double gompertz_f(const gsl_vector *v, void *params)
   { 
     double A,B,LL=0.0,sump=0.,num=0.;
     double *x= (double *) v->data;
     int i,n=0; /* n is the size of the sample */
   
     for (i=0;i<=imx-1 ; i++) {
       sump=sump+weight[i];
       /*    sump=sump+1;*/
       num=num+1;
     }
    
    
     /* for (i=0; i<=imx; i++) 
        if (wav[i]>0) printf("i=%d ageex=%lf agecens=%lf agedc=%lf cens=%d %d\n" ,i,ageexmed[i],agecens[i],agedc[i],cens[i],wav[i]);*/
     printf("x[0]=%lf x[1]=%lf\n",x[0],x[1]);
     for (i=1;i<=imx ; i++)
       {
         if (cens[i] == 1 && wav[i]>1)
           A=-x[0]/(x[1])*(exp(x[1]*(agecens[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)));
         
         if (cens[i] == 0 && wav[i]>1)
           A=-x[0]/(x[1])*(exp(x[1]*(agedc[i]-agegomp))-exp(x[1]*(ageexmed[i]-agegomp)))
                +log(x[0]/YEARM)+x[1]*(agedc[i]-agegomp)+log(YEARM);  
         
         /*if (wav[i] > 1 && agecens[i] > 15) {*/ /* ??? */
         if (wav[i] > 1 ) { /* ??? */
           LL=LL+A*weight[i];
           /*      printf("\ni=%d A=%f L=%lf x[1]=%lf x[2]=%lf ageex=%lf agecens=%lf cens=%d agedc=%lf weight=%lf\n",i,A,L,x[1],x[2],ageexmed[i]*12,agecens[i]*12,cens[i],agedc[i]*12,weight[i]);*/
         }
       }
   
    /*printf("x1=%2.9f x2=%2.9f x3=%2.9f L=%f\n",x[1],x[2],x[3],L);*/
     printf("x[0]=%lf x[1]=%lf -2*LL*num/sump=%lf\n",x[0],x[1],-2*LL*num/sump);
    
     return -2*LL*num/sump;
   }
   #endif
   
   /******************* Printing html file ***********/
   void printinghtmlmort(char fileresu[], char title[], char datafile[], int firstpass, \
                     int lastpass, int stepm, int weightopt, char model[],\
                     int imx,  double p[],double **matcov,double agemortsup){
     int i,k;
   
     fprintf(fichtm,"<ul><li><h4>Result files </h4>\n Force of mortality. Parameters of the Gompertz fit (with confidence interval in brackets):<br>");
     fprintf(fichtm,"  mu(age) =%lf*exp(%lf*(age-%d)) per year<br><br>",p[1],p[2],agegomp);
     for (i=1;i<=2;i++) 
       fprintf(fichtm," p[%d] = %lf [%f ; %f]<br>\n",i,p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
     fprintf(fichtm,"<br><br><img src=\"graphmort.svg\">");
     fprintf(fichtm,"</ul>");
   
   fprintf(fichtm,"<ul><li><h4>Life table</h4>\n <br>");
   
    fprintf(fichtm,"\nAge   l<inf>x</inf>     q<inf>x</inf> d(x,x+1)    L<inf>x</inf>     T<inf>x</inf>     e<infx</inf><br>");
   
    for (k=agegomp;k<(agemortsup-2);k++) 
      fprintf(fichtm,"%d %.0lf %lf %.0lf %.0lf %.0lf %lf<br>\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
   
    
     fflush(fichtm);
   }
   
   /******************* Gnuplot file **************/
   void printinggnuplotmort(char fileresu[], char optionfilefiname[], double ageminpar, double agemaxpar, double fage , char pathc[], double p[]){
   
     char dirfileres[132],optfileres[132];
   
     int ng;
   
   
     /*#ifdef windows */
     fprintf(ficgp,"cd \"%s\" \n",pathc);
       /*#endif */
   
   
     strcpy(dirfileres,optionfilefiname);
     strcpy(optfileres,"vpl");
     fprintf(ficgp,"set out \"graphmort.svg\"\n "); 
     fprintf(ficgp,"set xlabel \"Age\"\n set ylabel \"Force of mortality (per year)\" \n "); 
     fprintf(ficgp, "set ter svg size 640, 480\n set log y\n"); 
     /* fprintf(ficgp, "set size 0.65,0.65\n"); */
     fprintf(ficgp,"plot [%d:100] %lf*exp(%lf*(x-%d))",agegomp,p[1],p[2],agegomp);
   
   } 
   
   int readdata(char datafile[], int firstobs, int lastobs, int *imax)
   {
   
     /*-------- data file ----------*/
     FILE *fic;
     char dummy[]="                         ";
     int i=0, j=0, n=0;
     int linei, month, year,iout;
     char line[MAXLINE], linetmp[MAXLINE];
     char stra[MAXLINE], strb[MAXLINE];
     char *stratrunc;
     int lstra;
   
   
     if((fic=fopen(datafile,"r"))==NULL)    {
       printf("Problem while opening datafile: %s\n", datafile);fflush(stdout);
       fprintf(ficlog,"Problem while opening datafile: %s\n", datafile);fflush(ficlog);return 1;
     }
   
     i=1;
     linei=0;
     while ((fgets(line, MAXLINE, fic) != NULL) &&((i >= firstobs) && (i <=lastobs))) {
       linei=linei+1;
       for(j=strlen(line); j>=0;j--){  /* Untabifies line */
         if(line[j] == '\t')
           line[j] = ' ';
       }
       for(j=strlen(line)-1; (line[j]==' ')||(line[j]==10)||(line[j]==13);j--){
         ;
       };
       line[j+1]=0;  /* Trims blanks at end of line */
       if(line[0]=='#'){
         fprintf(ficlog,"Comment line\n%s\n",line);
         printf("Comment line\n%s\n",line);
         continue;
       }
       trimbb(linetmp,line); /* Trims multiple blanks in line */
       strcpy(line, linetmp);
     
   
       for (j=maxwav;j>=1;j--){
         cutv(stra, strb, line, ' '); 
         if(strb[0]=='.') { /* Missing status */
           lval=-1;
         }else{
           errno=0;
           lval=strtol(strb,&endptr,10); 
         /*        if (errno == ERANGE && (lval == LONG_MAX || lval == LONG_MIN))*/
           if( strb[0]=='\0' || (*endptr != '\0')){
             printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);
             fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a status of wave %d. Setting maxwav=%d might be wrong.  Exiting.\n", strb, linei,i,line,j,maxwav);fflush(ficlog);
             return 1;
           }
         }
         s[j][i]=lval;
         
         strcpy(line,stra);
         cutv(stra, strb,line,' ');
         if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
         }
         else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
           month=99;
           year=9999;
         }else{
           printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);
           fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of interview (mm/yyyy or .) at wave %d.  Exiting.\n",strb, linei,i, line,j);fflush(ficlog);
           return 1;
         }
         anint[j][i]= (double) year; 
         mint[j][i]= (double)month; 
         strcpy(line,stra);
       } /* ENd Waves */
       
       cutv(stra, strb,line,' '); 
       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
       }
       else  if( (iout=sscanf(strb,"%s.",dummy)) != 0){
         month=99;
         year=9999;
       }else{
         printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
           fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of death (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
           return 1;
       }
       andc[i]=(double) year; 
       moisdc[i]=(double) month; 
       strcpy(line,stra);
       
       cutv(stra, strb,line,' '); 
       if( (iout=sscanf(strb,"%d/%d",&month, &year)) != 0){
       }
       else  if( (iout=sscanf(strb,"%s.", dummy)) != 0){
         month=99;
         year=9999;
       }else{
         printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);
         fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy or .).  Exiting.\n",strb, linei,i,line);fflush(ficlog);
           return 1;
       }
       if (year==9999) {
         printf("Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given.  Exiting.\n",strb, linei,i,line);
         fprintf(ficlog,"Error reading data around '%s' at line number %d for individual %d, '%s'\nShould be a date of birth (mm/yyyy) but at least the year of birth should be given. Exiting.\n",strb, linei,i,line);fflush(ficlog);
           return 1;
   
       }
       annais[i]=(double)(year);
       moisnais[i]=(double)(month); 
       strcpy(line,stra);
       
       cutv(stra, strb,line,' '); 
       errno=0;
       dval=strtod(strb,&endptr); 
       if( strb[0]=='\0' || (*endptr != '\0')){
         printf("Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
         fprintf(ficlog,"Error reading data around '%f' at line number %d, \"%s\" for individual %d\nShould be a weight.  Exiting.\n",dval, i,line,linei);
         fflush(ficlog);
         return 1;
       }
       weight[i]=dval; 
       strcpy(line,stra);
       
       for (j=ncovcol;j>=1;j--){
         cutv(stra, strb,line,' '); 
         if(strb[0]=='.') { /* Missing status */
           lval=-1;
         }else{
           errno=0;
           lval=strtol(strb,&endptr,10); 
           if( strb[0]=='\0' || (*endptr != '\0')){
             printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);
             fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\nShould be a covariate value (=0 for the reference or 1 for alternative).  Exiting.\n",lval, linei,i, line);fflush(ficlog);
             return 1;
           }
         }
         if(lval <-1 || lval >1){
           printf("Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
    Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
    for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
    For example, for multinomial values like 1, 2 and 3,\n \
    build V1=0 V2=0 for the reference value (1),\n \
           V1=1 V2=0 for (2) \n \
    and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
    output of IMaCh is often meaningless.\n \
    Exiting.\n",lval,linei, i,line,j);
           fprintf(ficlog,"Error reading data around '%ld' at line number %d for individual %d, '%s'\n \
    Should be a value of %d(nth) covariate (0 should be the value for the reference and 1\n \
    for the alternative. IMaCh does not build design variables automatically, do it yourself.\n \
    For example, for multinomial values like 1, 2 and 3,\n \
    build V1=0 V2=0 for the reference value (1),\n \
           V1=1 V2=0 for (2) \n \
    and V1=0 V2=1 for (3). V1=1 V2=1 should not exist and the corresponding\n \
    output of IMaCh is often meaningless.\n \
    Exiting.\n",lval,linei, i,line,j);fflush(ficlog);
           return 1;
         }
         covar[j][i]=(double)(lval);
         strcpy(line,stra);
       }  
       lstra=strlen(stra);
        
       if(lstra > 9){ /* More than 2**32 or max of what printf can write with %ld */
         stratrunc = &(stra[lstra-9]);
         num[i]=atol(stratrunc);
       }
       else
         num[i]=atol(stra);
       /*if((s[2][i]==2) && (s[3][i]==-1)&&(s[4][i]==9)){
         printf("%ld %.lf %.lf %.lf %.lf/%.lf %.lf/%.lf %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d %.lf/%.lf %d\n",num[i],(covar[1][i]), (covar[2][i]),weight[i], (moisnais[i]), (annais[i]), (moisdc[i]), (andc[i]), (mint[1][i]), (anint[1][i]), (s[1][i]),  (mint[2][i]), (anint[2][i]), (s[2][i]),  (mint[3][i]), (anint[3][i]), (s[3][i]),  (mint[4][i]), (anint[4][i]), (s[4][i])); ij=ij+1;}*/
       
       i=i+1;
     } /* End loop reading  data */
   
     *imax=i-1; /* Number of individuals */
     fclose(fic);
    
     return (0);
     /* endread: */
       printf("Exiting readdata: ");
       fclose(fic);
       return (1);
   
   
   
   }
   void removespace(char *str) {
     char *p1 = str, *p2 = str;
     do
       while (*p2 == ' ')
         p2++;
     while (*p1++ == *p2++);
   }
   
   int decodemodel ( char model[], int lastobs) /**< This routine decode the model and returns:
      * Model  V1+V2+V3+V8+V7*V8+V5*V6+V8*age+V3*age+age*age
      * - nagesqr = 1 if age*age in the model, otherwise 0.
      * - cptcovt total number of covariates of the model nbocc(+)+1 = 8 excepting constant and age and age*age
      * - cptcovn or number of covariates k of the models excluding age*products =6 and age*age
      * - cptcovage number of covariates with age*products =2
      * - cptcovs number of simple covariates
      * - Tvar[k] is the id of the kth covariate Tvar[1]@12 {1, 2, 3, 8, 10, 11, 8, 3, 7, 8, 5, 6}, thus Tvar[5=V7*V8]=10
      *     which is a new column after the 9 (ncovcol) variables. 
      * - if k is a product Vn*Vm covar[k][i] is filled with correct values for each individual
      * - Tprod[l] gives the kth covariates of the product Vn*Vm l=1 to cptcovprod-cptcovage
      *    Tprod[1]@2 {5, 6}: position of first product V7*V8 is 5, and second V5*V6 is 6.
      * - Tvard[k]  p Tvard[1][1]@4 {7, 8, 5, 6} for V7*V8 and V5*V6 .
    */
   {
     int i, j, k, ks;
     int  j1, k1, k2;
     char modelsav[80];
     char stra[80], strb[80], strc[80], strd[80],stre[80];
     char *strpt;
   
     /*removespace(model);*/
     if (strlen(model) >1){ /* If there is at least 1 covariate */
       j=0, j1=0, k1=0, k2=-1, ks=0, cptcovn=0;
       if (strstr(model,"AGE") !=0){
         printf("Error. AGE must be in lower case 'age' model=1+age+%s. ",model);
         fprintf(ficlog,"Error. AGE must be in lower case model=1+age+%s. ",model);fflush(ficlog);
         return 1;
       }
       if (strstr(model,"v") !=0){
         printf("Error. 'v' must be in upper case 'V' model=%s ",model);
         fprintf(ficlog,"Error. 'v' must be in upper case model=%s ",model);fflush(ficlog);
         return 1;
       }
       strcpy(modelsav,model); 
       if ((strpt=strstr(model,"age*age")) !=0){
         printf(" strpt=%s, model=%s\n",strpt, model);
         if(strpt != model){
         printf("Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
    'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
    corresponding column of parameters.\n",model);
         fprintf(ficlog,"Error in model: 'model=%s'; 'age*age' should in first place before other covariates\n \
    'model=1+age+age*age+V1.' or 'model=1+age+age*age+V1+V1*age.', please swap as well as \n \
    corresponding column of parameters.\n",model); fflush(ficlog);
         return 1;
       }
   
         nagesqr=1;
         if (strstr(model,"+age*age") !=0)
           substrchaine(modelsav, model, "+age*age");
         else if (strstr(model,"age*age+") !=0)
           substrchaine(modelsav, model, "age*age+");
         else 
           substrchaine(modelsav, model, "age*age");
       }else
         nagesqr=0;
       if (strlen(modelsav) >1){
         j=nbocc(modelsav,'+'); /**< j=Number of '+' */
         j1=nbocc(modelsav,'*'); /**< j1=Number of '*' */
         cptcovs=j+1-j1; /**<  Number of simple covariates V1+V1*age+V3 +V3*V4+age*age=> V1 + V3 =2  */
         cptcovt= j+1; /* Number of total covariates in the model, not including
                      * cst, age and age*age 
                      * V1+V1*age+ V3 + V3*V4+age*age=> 4*/
                     /* including age products which are counted in cptcovage.
                     * but the covariates which are products must be treated 
                     * separately: ncovn=4- 2=2 (V1+V3). */
         cptcovprod=j1; /**< Number of products  V1*V2 +v3*age = 2 */
         cptcovprodnoage=0; /**< Number of covariate products without age: V3*V4 =1  */
   
       
         /*   Design
          *  V1   V2   V3   V4  V5  V6  V7  V8  V9 Weight
          *  <          ncovcol=8                >
          * Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8
          *   k=  1    2      3       4     5       6      7        8
          *  cptcovn number of covariates (not including constant and age ) = # of + plus 1 = 7+1=8
          *  covar[k,i], value of kth covariate if not including age for individual i:
          *       covar[1][i]= (V2), covar[4][i]=(V3), covar[8][i]=(V8)
          *  Tvar[k] # of the kth covariate:  Tvar[1]=2  Tvar[4]=3 Tvar[8]=8
          *       if multiplied by age: V3*age Tvar[3=V3*age]=3 (V3) Tvar[7]=8 and 
          *  Tage[++cptcovage]=k
          *       if products, new covar are created after ncovcol with k1
          *  Tvar[k]=ncovcol+k1; # of the kth covariate product:  Tvar[5]=ncovcol+1=10  Tvar[6]=ncovcol+1=11
          *  Tprod[k1]=k; Tprod[1]=5 Tprod[2]= 6; gives the position of the k1th product
          *  Tvard[k1][1]=m Tvard[k1][2]=m; Tvard[1][1]=5 (V5) Tvard[1][2]=6 Tvard[2][1]=7 (V7) Tvard[2][2]=8
          *  Tvar[cptcovn+k2]=Tvard[k1][1];Tvar[cptcovn+k2+1]=Tvard[k1][2];
          *  Tvar[8+1]=5;Tvar[8+2]=6;Tvar[8+3]=7;Tvar[8+4]=8 inverted
          *  V1   V2   V3   V4  V5  V6  V7  V8  V9  V10  V11
          *  <          ncovcol=8                >
          *       Model V2 + V1 + V3*age + V3 + V5*V6 + V7*V8 + V8*age + V8    d1   d1   d2  d2
          *          k=  1    2      3       4     5       6      7        8    9   10   11  12
          *     Tvar[k]= 2    1      3       3    10      11      8        8    5    6    7   8
          * p Tvar[1]@12={2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
          * p Tprod[1]@2={                         6, 5}
          *p Tvard[1][1]@4= {7, 8, 5, 6}
          * covar[k][i]= V2   V1      ?      V3    V5*V6?   V7*V8?  ?       V8   
          *  cov[Tage[kk]+2]=covar[Tvar[Tage[kk]]][i]*cov[2];
          *How to reorganize?
          * Model V1 + V2 + V3 + V8 + V5*V6 + V7*V8 + V3*age + V8*age
          * Tvars {2,   1,     3,      3,   11,     10,     8,       8,   7,   8,   5,  6}
          *       {2,   1,     4,      8,    5,      6,     3,       7}
          * Struct []
          */
   
         /* This loop fills the array Tvar from the string 'model'.*/
         /* j is the number of + signs in the model V1+V2+V3 j=2 i=3 to 1 */
         /*   modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4  */
         /*        k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tage[cptcovage=1]=4 */
         /*        k=3 V4 Tvar[k=3]= 4 (from V4) */
         /*        k=2 V1 Tvar[k=2]= 1 (from V1) */
         /*        k=1 Tvar[1]=2 (from V2) */
         /*        k=5 Tvar[5] */
         /* for (k=1; k<=cptcovn;k++) { */
         /*        cov[2+k]=nbcode[Tvar[k]][codtabm(ij,Tvar[k])]; */
         /*        } */
         /* for (k=1; k<=cptcovage;k++) cov[2+Tage[k]]=nbcode[Tvar[Tage[k]]][codtabm(ij,Tvar[Tage[k])]]*cov[2]; */
         /*
          * Treating invertedly V2+V1+V3*age+V2*V4 is as if written V2*V4 +V3*age + V1 + V2 */
         for(k=cptcovt; k>=1;k--) /**< Number of covariates */
           Tvar[k]=0;
         cptcovage=0;
         for(k=1; k<=cptcovt;k++){ /* Loop on total covariates of the model */
           cutl(stra,strb,modelsav,'+'); /* keeps in strb after the first '+' 
                                            modelsav==V2+V1+V4+V3*age strb=V3*age stra=V2+V1+V4 */ 
           if (nbocc(modelsav,'+')==0) strcpy(strb,modelsav); /* and analyzes it */
           /*      printf("i=%d a=%s b=%s sav=%s\n",i, stra,strb,modelsav);*/
           /*scanf("%d",i);*/
           if (strchr(strb,'*')) {  /**< Model includes a product V2+V1+V4+V3*age strb=V3*age */
             cutl(strc,strd,strb,'*'); /**< strd*strc  Vm*Vn: strb=V3*age(input) strc=age strd=V3 ; V3*V2 strc=V2, strd=V3 */
             if (strcmp(strc,"age")==0) { /**< Model includes age: Vn*age */
               /* covar is not filled and then is empty */
               cptcovprod--;
               cutl(stre,strb,strd,'V'); /* strd=V3(input): stre="3" */
               Tvar[k]=atoi(stre);  /* V2+V1+V4+V3*age Tvar[4]=3 ; V1+V2*age Tvar[2]=2; V1+V1*age Tvar[2]=1 */
               cptcovage++; /* Sums the number of covariates which include age as a product */
               Tage[cptcovage]=k;  /* Tvar[4]=3, Tage[1] = 4 or V1+V1*age Tvar[2]=1, Tage[1]=2 */
               /*printf("stre=%s ", stre);*/
             } else if (strcmp(strd,"age")==0) { /* or age*Vn */
               cptcovprod--;
               cutl(stre,strb,strc,'V');
               Tvar[k]=atoi(stre);
               cptcovage++;
               Tage[cptcovage]=k;
             } else {  /* Age is not in the model product V2+V1+V1*V4+V3*age+V3*V2  strb=V3*V2*/
               /* loops on k1=1 (V3*V2) and k1=2 V4*V3 */
               cptcovn++;
               cptcovprodnoage++;k1++;
               cutl(stre,strb,strc,'V'); /* strc= Vn, stre is n; strb=V3*V2 stre=3 strc=*/
               Tvar[k]=ncovcol+k1; /* For model-covariate k tells which data-covariate to use but
                                      because this model-covariate is a construction we invent a new column
                                      ncovcol + k1
                                      If already ncovcol=4 and model=V2+V1+V1*V4+age*V3+V3*V2
                                      Tvar[3=V1*V4]=4+1 Tvar[5=V3*V2]=4 + 2= 6, etc */
               cutl(strc,strb,strd,'V'); /* strd was Vm, strc is m */
               Tprod[k1]=k;  /* Tprod[1]=3(=V1*V4) for V2+V1+V1*V4+age*V3+V3*V2  */
               Tvard[k1][1] =atoi(strc); /* m 1 for V1*/
               Tvard[k1][2] =atoi(stre); /* n 4 for V4*/
               k2=k2+2;
               Tvar[cptcovt+k2]=Tvard[k1][1]; /* Tvar[(cptcovt=4+k2=1)=5]= 1 (V1) */
               Tvar[cptcovt+k2+1]=Tvard[k1][2];  /* Tvar[(cptcovt=4+(k2=1)+1)=6]= 4 (V4) */
               for (i=1; i<=lastobs;i++){
                 /* Computes the new covariate which is a product of
                    covar[n][i]* covar[m][i] and stores it at ncovol+k1 May not be defined */
                 covar[ncovcol+k1][i]=covar[atoi(stre)][i]*covar[atoi(strc)][i];
               }
             } /* End age is not in the model */
           } /* End if model includes a product */
           else { /* no more sum */
             /*printf("d=%s c=%s b=%s\n", strd,strc,strb);*/
             /*  scanf("%d",i);*/
             cutl(strd,strc,strb,'V');
             ks++; /**< Number of simple covariates */
             cptcovn++;
             Tvar[k]=atoi(strd);
           }
           strcpy(modelsav,stra);  /* modelsav=V2+V1+V4 stra=V2+V1+V4 */ 
           /*printf("a=%s b=%s sav=%s\n", stra,strb,modelsav);
             scanf("%d",i);*/
         } /* end of loop + on total covariates */
       } /* end if strlen(modelsave == 0) age*age might exist */
     } /* end if strlen(model == 0) */
     
     /*The number n of Vn is stored in Tvar. cptcovage =number of age covariate. Tage gives the position of age. cptcovprod= number of products.
       If model=V1+V1*age then Tvar[1]=1 Tvar[2]=1 cptcovage=1 Tage[1]=2 cptcovprod=0*/
   
     /* printf("tvar1=%d tvar2=%d tvar3=%d cptcovage=%d Tage=%d",Tvar[1],Tvar[2],Tvar[3],cptcovage,Tage[1]);
     printf("cptcovprod=%d ", cptcovprod);
     fprintf(ficlog,"cptcovprod=%d ", cptcovprod);
   
     scanf("%d ",i);*/
   
   
     return (0); /* with covar[new additional covariate if product] and Tage if age */ 
     /*endread:*/
       printf("Exiting decodemodel: ");
       return (1);
   }
   
   int calandcheckages(int imx, int maxwav, double *agemin, double *agemax, int *nberr, int *nbwarn )
   {
     int i, m;
   
     for (i=1; i<=imx; i++) {
       for(m=2; (m<= maxwav); m++) {
         if (((int)mint[m][i]== 99) && (s[m][i] <= nlstate)){
           anint[m][i]=9999;
           s[m][i]=-1;
         }
         if((int)moisdc[i]==99 && (int)andc[i]==9999 && s[m][i]>nlstate){
           *nberr = *nberr + 1;
           printf("Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results are biased (%d)\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr);
           fprintf(ficlog,"Error! Date of death (month %2d and year %4d) of individual %ld on line %d was unknown, you must set an arbitrary year of death or he/she is skipped and results are biased (%d)\n",(int)moisdc[i],(int)andc[i],num[i],i, *nberr);
           s[m][i]=-1;
         }
         if((int)moisdc[i]==99 && (int)andc[i]!=9999 && s[m][i]>nlstate){
           (*nberr)++;
           printf("Error! Month of death of individual %ld on line %d was unknown %2d, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,(int)moisdc[i]); 
           fprintf(ficlog,"Error! Month of death of individual %ld on line %d was unknown %f, you should set it otherwise the information on the death is skipped and results are biased.\n",num[i],i,moisdc[i]); 
           s[m][i]=-1; /* We prefer to skip it (and to skip it in version 0.8a1 too */
         }
       }
     }
   
     for (i=1; i<=imx; i++)  {
       agedc[i]=(moisdc[i]/12.+andc[i])-(moisnais[i]/12.+annais[i]);
       for(m=firstpass; (m<= lastpass); m++){
         if(s[m][i] >0 || s[m][i]==-2 || s[m][i]==-4 || s[m][i]==-5){
           if (s[m][i] >= nlstate+1) {
             if(agedc[i]>0){
               if((int)moisdc[i]!=99 && (int)andc[i]!=9999){
                 agev[m][i]=agedc[i];
             /*if(moisdc[i]==99 && andc[i]==9999) s[m][i]=-1;*/
               }else {
                 if ((int)andc[i]!=9999){
                   nbwarn++;
                   printf("Warning negative age at death: %ld line:%d\n",num[i],i);
                   fprintf(ficlog,"Warning negative age at death: %ld line:%d\n",num[i],i);
                   agev[m][i]=-1;
                 }
               }
             } /* agedc > 0 */
           }
           else if(s[m][i] !=9){ /* Standard case, age in fractional
                                    years but with the precision of a month */
             agev[m][i]=(mint[m][i]/12.+1./24.+anint[m][i])-(moisnais[i]/12.+1./24.+annais[i]);
             if((int)mint[m][i]==99 || (int)anint[m][i]==9999)
               agev[m][i]=1;
             else if(agev[m][i] < *agemin){ 
               *agemin=agev[m][i];
               printf(" Min anint[%d][%d]=%.2f annais[%d]=%.2f, agemin=%.2f\n",m,i,anint[m][i], i,annais[i], *agemin);
             }
             else if(agev[m][i] >*agemax){
               *agemax=agev[m][i];
               /* printf(" Max anint[%d][%d]=%.0f annais[%d]=%.0f, agemax=%.2f\n",m,i,anint[m][i], i,annais[i], *agemax);*/
             }
             /*agev[m][i]=anint[m][i]-annais[i];*/
             /*     agev[m][i] = age[i]+2*m;*/
           }
           else { /* =9 */
             agev[m][i]=1;
             s[m][i]=-1;
           }
         }
         else /*= 0 Unknown */
           agev[m][i]=1;
       }
       
     }
     for (i=1; i<=imx; i++)  {
       for(m=firstpass; (m<=lastpass); m++){
         if (s[m][i] > (nlstate+ndeath)) {
           (*nberr)++;
           printf("Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
           fprintf(ficlog,"Error: on wave %d of individual %d status %d > (nlstate+ndeath)=(%d+%d)=%d\n",m,i,s[m][i],nlstate, ndeath, nlstate+ndeath);     
           return 1;
         }
       }
     }
   
     /*for (i=1; i<=imx; i++){
     for (m=firstpass; (m<lastpass); m++){
        printf("%ld %d %.lf %d %d\n", num[i],(covar[1][i]),agev[m][i],s[m][i],s[m+1][i]);
   }
   
   }*/
   
   
     printf("Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax);
     fprintf(ficlog,"Total number of individuals= %d, Agemin = %.2f, Agemax= %.2f\n\n", imx, *agemin, *agemax); 
   
     return (0);
    /* endread:*/
       printf("Exiting calandcheckages: ");
       return (1);
   }
   
   #if defined(_MSC_VER)
   /*printf("Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
   /*fprintf(ficlog, "Visual C++ compiler: %s \n;", _MSC_FULL_VER);*/
   //#include "stdafx.h"
   //#include <stdio.h>
   //#include <tchar.h>
   //#include <windows.h>
   //#include <iostream>
   typedef BOOL(WINAPI *LPFN_ISWOW64PROCESS) (HANDLE, PBOOL);
   
   LPFN_ISWOW64PROCESS fnIsWow64Process;
   
   BOOL IsWow64()
   {
           BOOL bIsWow64 = FALSE;
   
           //typedef BOOL (APIENTRY *LPFN_ISWOW64PROCESS)
           //  (HANDLE, PBOOL);
   
           //LPFN_ISWOW64PROCESS fnIsWow64Process;
   
           HMODULE module = GetModuleHandle(_T("kernel32"));
           const char funcName[] = "IsWow64Process";
           fnIsWow64Process = (LPFN_ISWOW64PROCESS)
                   GetProcAddress(module, funcName);
   
           if (NULL != fnIsWow64Process)
           {
                   if (!fnIsWow64Process(GetCurrentProcess(),
                           &bIsWow64))
                           //throw std::exception("Unknown error");
                           printf("Unknown error\n");
           }
           return bIsWow64 != FALSE;
   }
   #endif
   
   void syscompilerinfo(int logged)
    {
      /* #include "syscompilerinfo.h"*/
      /* command line Intel compiler 32bit windows, XP compatible:*/
      /* /GS /W3 /Gy
         /Zc:wchar_t /Zi /O2 /Fd"Release\vc120.pdb" /D "WIN32" /D "NDEBUG" /D
         "_CONSOLE" /D "_LIB" /D "_USING_V110_SDK71_" /D "_UNICODE" /D
         "UNICODE" /Qipo /Zc:forScope /Gd /Oi /MT /Fa"Release\" /EHsc /nologo
         /Fo"Release\" /Qprof-dir "Release\" /Fp"Release\IMaCh.pch"
      */ 
      /* 64 bits */
      /*
        /GS /W3 /Gy
        /Zc:wchar_t /Zi /O2 /Fd"x64\Release\vc120.pdb" /D "WIN32" /D "NDEBUG"
        /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo /Zc:forScope
        /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Fo"x64\Release\" /Qprof-dir
        "x64\Release\" /Fp"x64\Release\IMaCh.pch" */
      /* Optimization are useless and O3 is slower than O2 */
      /*
        /GS /W3 /Gy /Zc:wchar_t /Zi /O3 /Fd"x64\Release\vc120.pdb" /D "WIN32" 
        /D "NDEBUG" /D "_CONSOLE" /D "_LIB" /D "_UNICODE" /D "UNICODE" /Qipo 
        /Zc:forScope /Oi /MD /Fa"x64\Release\" /EHsc /nologo /Qparallel 
        /Fo"x64\Release\" /Qprof-dir "x64\Release\" /Fp"x64\Release\IMaCh.pch" 
      */
      /* Link is */ /* /OUT:"visual studio
         2013\Projects\IMaCh\Release\IMaCh.exe" /MANIFEST /NXCOMPAT
         /PDB:"visual studio
         2013\Projects\IMaCh\Release\IMaCh.pdb" /DYNAMICBASE
         "kernel32.lib" "user32.lib" "gdi32.lib" "winspool.lib"
         "comdlg32.lib" "advapi32.lib" "shell32.lib" "ole32.lib"
         "oleaut32.lib" "uuid.lib" "odbc32.lib" "odbccp32.lib"
         /MACHINE:X86 /OPT:REF /SAFESEH /INCREMENTAL:NO
         /SUBSYSTEM:CONSOLE",5.01" /MANIFESTUAC:"level='asInvoker'
         uiAccess='false'"
         /ManifestFile:"Release\IMaCh.exe.intermediate.manifest" /OPT:ICF
         /NOLOGO /TLBID:1
      */
   #if defined __INTEL_COMPILER
   #if defined(__GNUC__)
           struct utsname sysInfo;  /* For Intel on Linux and OS/X */
   #endif
   #elif defined(__GNUC__) 
   #ifndef  __APPLE__
   #include <gnu/libc-version.h>  /* Only on gnu */
   #endif
      struct utsname sysInfo;
      int cross = CROSS;
      if (cross){
              printf("Cross-");
              if(logged) fprintf(ficlog, "Cross-");
      }
   #endif
   
   #include <stdint.h>
   
      printf("Compiled with:");if(logged)fprintf(ficlog,"Compiled with:");
   #if defined(__clang__)
      printf(" Clang/LLVM");if(logged)fprintf(ficlog," Clang/LLVM");       /* Clang/LLVM. ---------------------------------------------- */
   #endif
   #if defined(__ICC) || defined(__INTEL_COMPILER)
      printf(" Intel ICC/ICPC");if(logged)fprintf(ficlog," Intel ICC/ICPC");/* Intel ICC/ICPC. ------------------------------------------ */
   #endif
   #if defined(__GNUC__) || defined(__GNUG__)
      printf(" GNU GCC/G++");if(logged)fprintf(ficlog," GNU GCC/G++");/* GNU GCC/G++. --------------------------------------------- */
   #endif
   #if defined(__HP_cc) || defined(__HP_aCC)
      printf(" Hewlett-Packard C/aC++");if(logged)fprintf(fcilog," Hewlett-Packard C/aC++"); /* Hewlett-Packard C/aC++. ---------------------------------- */
   #endif
   #if defined(__IBMC__) || defined(__IBMCPP__)
      printf(" IBM XL C/C++"); if(logged) fprintf(ficlog," IBM XL C/C++");/* IBM XL C/C++. -------------------------------------------- */
   #endif
   #if defined(_MSC_VER)
      printf(" Microsoft Visual Studio");if(logged)fprintf(ficlog," Microsoft Visual Studio");/* Microsoft Visual Studio. --------------------------------- */
   #endif
   #if defined(__PGI)
      printf(" Portland Group PGCC/PGCPP");if(logged) fprintf(ficlog," Portland Group PGCC/PGCPP");/* Portland Group PGCC/PGCPP. ------------------------------- */
   #endif
   #if defined(__SUNPRO_C) || defined(__SUNPRO_CC)
      printf(" Oracle Solaris Studio");if(logged)fprintf(ficlog," Oracle Solaris Studio\n");/* Oracle Solaris Studio. ----------------------------------- */
   #endif
      printf(" for "); if (logged) fprintf(ficlog, " for ");
      
   // http://stackoverflow.com/questions/4605842/how-to-identify-platform-compiler-from-preprocessor-macros
   #ifdef _WIN32 // note the underscore: without it, it's not msdn official!
       // Windows (x64 and x86)
      printf("Windows (x64 and x86) ");if(logged) fprintf(ficlog,"Windows (x64 and x86) ");
   #elif __unix__ // all unices, not all compilers
       // Unix
      printf("Unix ");if(logged) fprintf(ficlog,"Unix ");
   #elif __linux__
       // linux
      printf("linux ");if(logged) fprintf(ficlog,"linux ");
   #elif __APPLE__
       // Mac OS, not sure if this is covered by __posix__ and/or __unix__ though..
      printf("Mac OS ");if(logged) fprintf(ficlog,"Mac OS ");
   #endif
   
   /*  __MINGW32__   */
   /*  __CYGWIN__   */
   /* __MINGW64__  */
   // http://msdn.microsoft.com/en-us/library/b0084kay.aspx
   /* _MSC_VER  //the Visual C++ compiler is 17.00.51106.1, the _MSC_VER macro evaluates to 1700. Type cl /?  */
   /* _MSC_FULL_VER //the Visual C++ compiler is 15.00.20706.01, the _MSC_FULL_VER macro evaluates to 150020706 */
   /* _WIN64  // Defined for applications for Win64. */
   /* _M_X64 // Defined for compilations that target x64 processors. */
   /* _DEBUG // Defined when you compile with /LDd, /MDd, and /MTd. */
   
   #if UINTPTR_MAX == 0xffffffff
      printf(" 32-bit"); if(logged) fprintf(ficlog," 32-bit");/* 32-bit */
   #elif UINTPTR_MAX == 0xffffffffffffffff
      printf(" 64-bit"); if(logged) fprintf(ficlog," 64-bit");/* 64-bit */
   #else
      printf(" wtf-bit"); if(logged) fprintf(ficlog," wtf-bit");/* wtf */
   #endif
   
   #if defined(__GNUC__)
   # if defined(__GNUC_PATCHLEVEL__)
   #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                               + __GNUC_MINOR__ * 100 \
                               + __GNUC_PATCHLEVEL__)
   # else
   #  define __GNUC_VERSION__ (__GNUC__ * 10000 \
                               + __GNUC_MINOR__ * 100)
   # endif
      printf(" using GNU C version %d.\n", __GNUC_VERSION__);
      if(logged) fprintf(ficlog, " using GNU C version %d.\n", __GNUC_VERSION__);
   
      if (uname(&sysInfo) != -1) {
        printf("Running on: %s %s %s %s %s\n",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
            if(logged) fprintf(ficlog,"Running on: %s %s %s %s %s\n ",sysInfo.sysname, sysInfo.nodename, sysInfo.release, sysInfo.version, sysInfo.machine);
      }
      else
         perror("uname() error");
      //#ifndef __INTEL_COMPILER 
   #if !defined (__INTEL_COMPILER) && !defined(__APPLE__)
      printf("GNU libc version: %s\n", gnu_get_libc_version()); 
      if(logged) fprintf(ficlog,"GNU libc version: %s\n", gnu_get_libc_version());
   #endif
   #endif
   
      //   void main()
      //   {
   #if defined(_MSC_VER)
      if (IsWow64()){
              printf("\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
              if (logged) fprintf(ficlog, "\nThe program (probably compiled for 32bit) is running under WOW64 (64bit) emulation.\n");
      }
      else{
              printf("\nThe program is not running under WOW64 (i.e probably on a 64bit Windows).\n");
              if (logged) fprintf(ficlog, "\nThe programm is not running under WOW64 (i.e probably on a 64bit Windows).\n");
      }
      //      printf("\nPress Enter to continue...");
      //      getchar();
      //   }
   
   #endif
      
   
    }
   
    int prevalence_limit(double *p, double **prlim, double ageminpar, double agemaxpar, double ftolpl, int *ncvyearp){
     /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
     int i, j, k, i1 ;
     /* double ftolpl = 1.e-10; */
     double age, agebase, agelim;
     double tot;
   
     strcpy(filerespl,"PL_");
     strcat(filerespl,fileresu);
     if((ficrespl=fopen(filerespl,"w"))==NULL) {
       printf("Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
       fprintf(ficlog,"Problem with period (stable) prevalence resultfile: %s\n", filerespl);return 1;
     }
     printf("Computing period (stable) prevalence: result on file '%s' \n", filerespl);
     fprintf(ficlog,"Computing period (stable) prevalence: result on file '%s' \n", filerespl);
     pstamp(ficrespl);
     fprintf(ficrespl,"# Period (stable) prevalence. Precision given by ftolpl=%g \n", ftolpl);
     fprintf(ficrespl,"#Age ");
     for(i=1; i<=nlstate;i++) fprintf(ficrespl,"%d-%d ",i,i);
     fprintf(ficrespl,"\n");
     
       /* prlim=matrix(1,nlstate,1,nlstate);*/ /* back in main */
   
       agebase=ageminpar;
       agelim=agemaxpar;
   
       i1=pow(2,cptcoveff);
       if (cptcovn < 1){i1=1;}
   
       for(cptcov=1,k=0;cptcov<=i1;cptcov++){
       /* for(cptcov=1,k=0;cptcov<=1;cptcov++){ */
         //for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){
           k=k+1;
           /* to clean */
           //printf("cptcov=%d cptcod=%d codtab=%d\n",cptcov, cptcod,codtabm(cptcod,cptcov));
           fprintf(ficrespl,"#******");
           printf("#******");
           fprintf(ficlog,"#******");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficrespl," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
             printf(" V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
             fprintf(ficlog," V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
           }
           fprintf(ficrespl,"******\n");
           printf("******\n");
           fprintf(ficlog,"******\n");
   
           fprintf(ficrespl,"#Age ");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficrespl,"V%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
           }
           for(i=1; i<=nlstate;i++) fprintf(ficrespl,"  %d-%d   ",i,i);
           fprintf(ficrespl,"Total Years_to_converge\n");
           
           for (age=agebase; age<=agelim; age++){
           /* for (age=agebase; age<=agebase; age++){ */
             prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, ncvyearp, k);
             fprintf(ficrespl,"%.0f ",age );
             for(j=1;j<=cptcoveff;j++)
               fprintf(ficrespl,"%d %d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
             tot=0.;
             for(i=1; i<=nlstate;i++){
               tot +=  prlim[i][i];
               fprintf(ficrespl," %.5f", prlim[i][i]);
             }
             fprintf(ficrespl," %.3f %d\n", tot, *ncvyearp);
           } /* Age */
           /* was end of cptcod */
       } /* cptcov */
           return 0;
   }
   
   int hPijx(double *p, int bage, int fage){
       /*------------- h Pij x at various ages ------------*/
   
     int stepsize;
     int agelim;
     int hstepm;
     int nhstepm;
     int h, i, i1, j, k;
   
     double agedeb;
     double ***p3mat;
   
       strcpy(filerespij,"PIJ_");  strcat(filerespij,fileresu);
       if((ficrespij=fopen(filerespij,"w"))==NULL) {
         printf("Problem with Pij resultfile: %s\n", filerespij); return 1;
         fprintf(ficlog,"Problem with Pij resultfile: %s\n", filerespij); return 1;
       }
       printf("Computing pij: result on file '%s' \n", filerespij);
       fprintf(ficlog,"Computing pij: result on file '%s' \n", filerespij);
     
       stepsize=(int) (stepm+YEARM-1)/YEARM;
       /*if (stepm<=24) stepsize=2;*/
   
       agelim=AGESUP;
       hstepm=stepsize*YEARM; /* Every year of age */
       hstepm=hstepm/stepm; /* Typically 2 years, = 2/6 months = 4 */ 
   
       /* hstepm=1;   aff par mois*/
       pstamp(ficrespij);
       fprintf(ficrespij,"#****** h Pij x Probability to be in state j at age x+h being in i at x ");
       i1= pow(2,cptcoveff);
      /* for(cptcov=1,k=0;cptcov<=i1;cptcov++){ */
      /*    /\*for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*\/ */
      /*   k=k+1;  */
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
         fprintf(ficrespij,"\n#****** ");
         for(j=1;j<=cptcoveff;j++) 
           fprintf(ficrespij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
         fprintf(ficrespij,"******\n");
         
         for (agedeb=fage; agedeb>=bage; agedeb--){ /* If stepm=6 months */
           nhstepm=(int) rint((agelim-agedeb)*YEARM/stepm); /* Typically 20 years = 20*12/6=40 */ 
           nhstepm = nhstepm/hstepm; /* Typically 40/4=10 */
           
           /*        nhstepm=nhstepm*YEARM; aff par mois*/
           
           p3mat=ma3x(1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           oldm=oldms;savm=savms;
           hpxij(p3mat,nhstepm,agedeb,hstepm,p,nlstate,stepm,oldm,savm, k);  
           fprintf(ficrespij,"# Cov Agex agex+h hpijx with i,j=");
           for(i=1; i<=nlstate;i++)
             for(j=1; j<=nlstate+ndeath;j++)
               fprintf(ficrespij," %1d-%1d",i,j);
           fprintf(ficrespij,"\n");
           for (h=0; h<=nhstepm; h++){
             /*agedebphstep = agedeb + h*hstepm/YEARM*stepm;*/
             fprintf(ficrespij,"%d %3.f %3.f",k, agedeb, agedeb + h*hstepm/YEARM*stepm );
             for(i=1; i<=nlstate;i++)
               for(j=1; j<=nlstate+ndeath;j++)
                 fprintf(ficrespij," %.5f", p3mat[i][j][h]);
             fprintf(ficrespij,"\n");
           }
           free_ma3x(p3mat,1,nlstate+ndeath,1, nlstate+ndeath, 0,nhstepm);
           fprintf(ficrespij,"\n");
         }
         /*}*/
       }
           return 0;
   }
   
   
   /***********************************************/
   /**************** Main Program *****************/
   /***********************************************/
   
   int main(int argc, char *argv[])
   {
   #ifdef GSL
     const gsl_multimin_fminimizer_type *T;
     size_t iteri = 0, it;
     int rval = GSL_CONTINUE;
     int status = GSL_SUCCESS;
     double ssval;
   #endif
     int movingaverage(double ***probs, double bage,double fage, double ***mobaverage, int mobilav);
     int i,j, k, n=MAXN,iter=0,m,size=100, cptcod;
     int ncvyear=0; /* Number of years needed for the period prevalence to converge */
     int jj, ll, li, lj, lk;
     int numlinepar=0; /* Current linenumber of parameter file */
     int num_filled;
     int itimes;
     int NDIM=2;
     int vpopbased=0;
   
     char ca[32], cb[32];
     /*  FILE *fichtm; *//* Html File */
     /* FILE *ficgp;*/ /*Gnuplot File */
     struct stat info;
     double agedeb=0.;
   
     double ageminpar=AGEOVERFLOW,agemin=AGEOVERFLOW, agemaxpar=-AGEOVERFLOW, agemax=-AGEOVERFLOW;
   
     double fret;
     double dum=0.; /* Dummy variable */
     double ***p3mat;
     double ***mobaverage;
   
     char line[MAXLINE];
     char path[MAXLINE],pathc[MAXLINE],pathcd[MAXLINE],pathtot[MAXLINE];
   
     char model[MAXLINE], modeltemp[MAXLINE];
     char pathr[MAXLINE], pathimach[MAXLINE]; 
     char *tok, *val; /* pathtot */
     int firstobs=1, lastobs=10;
     int c,  h , cpt, c2;
     int jl=0;
     int i1, j1, jk, stepsize=0;
     int count=0;
   
     int *tab; 
     int mobilavproj=0 , prevfcast=0 ; /* moving average of prev, If prevfcast=1 prevalence projection */
     int mobilav=0,popforecast=0;
     int hstepm=0, nhstepm=0;
     int agemortsup;
     float  sumlpop=0.;
     double jprev1=1, mprev1=1,anprev1=2000,jprev2=1, mprev2=1,anprev2=2000;
     double jpyram=1, mpyram=1,anpyram=2000,jpyram1=1, mpyram1=1,anpyram1=2000;
   
     double bage=0, fage=110., age, agelim=0., agebase=0.;
     double ftolpl=FTOL;
     double **prlim;
     double ***param; /* Matrix of parameters */
     double  *p;
     double **matcov; /* Matrix of covariance */
     double **hess; /* Hessian matrix */
     double ***delti3; /* Scale */
     double *delti; /* Scale */
     double ***eij, ***vareij;
     double **varpl; /* Variances of prevalence limits by age */
     double *epj, vepp;
   
     double dateprev1, dateprev2,jproj1=1,mproj1=1,anproj1=2000,jproj2=1,mproj2=1,anproj2=2000;
     double **ximort;
     char *alph[]={"a","a","b","c","d","e"}, str[4]="1234";
     int *dcwave;
   
     char z[1]="c";
   
     /*char  *strt;*/
     char strtend[80];
   
   
   /*   setlocale (LC_ALL, ""); */
   /*   bindtextdomain (PACKAGE, LOCALEDIR); */
   /*   textdomain (PACKAGE); */
   /*   setlocale (LC_CTYPE, ""); */
   /*   setlocale (LC_MESSAGES, ""); */
   
     /*   gettimeofday(&start_time, (struct timezone*)0); */ /* at first time */
     rstart_time = time(NULL);  
     /*  (void) gettimeofday(&start_time,&tzp);*/
     start_time = *localtime(&rstart_time);
     curr_time=start_time;
     /*tml = *localtime(&start_time.tm_sec);*/
     /* strcpy(strstart,asctime(&tml)); */
     strcpy(strstart,asctime(&start_time));
   
   /*  printf("Localtime (at start)=%s",strstart); */
   /*  tp.tm_sec = tp.tm_sec +86400; */
   /*  tm = *localtime(&start_time.tm_sec); */
   /*   tmg.tm_year=tmg.tm_year +dsign*dyear; */
   /*   tmg.tm_mon=tmg.tm_mon +dsign*dmonth; */
   /*   tmg.tm_hour=tmg.tm_hour + 1; */
   /*   tp.tm_sec = mktime(&tmg); */
   /*   strt=asctime(&tmg); */
   /*   printf("Time(after) =%s",strstart);  */
   /*  (void) time (&time_value);
   *  printf("time=%d,t-=%d\n",time_value,time_value-86400);
   *  tm = *localtime(&time_value);
   *  strstart=asctime(&tm);
   *  printf("tim_value=%d,asctime=%s\n",time_value,strstart); 
   */
   
     nberr=0; /* Number of errors and warnings */
     nbwarn=0;
   #ifdef WIN32
     _getcwd(pathcd, size);
   #else
     getcwd(pathcd, size);
   #endif
     syscompilerinfo(0);
     printf("\nIMaCh version %s, %s\n%s",version, copyright, fullversion);
     if(argc <=1){
       printf("\nEnter the parameter file name: ");
       if(!fgets(pathr,FILENAMELENGTH,stdin)){
         printf("ERROR Empty parameter file name\n");
         goto end;
       }
       i=strlen(pathr);
       if(pathr[i-1]=='\n')
         pathr[i-1]='\0';
       i=strlen(pathr);
       if(i >= 1 && pathr[i-1]==' ') {/* This may happen when dragging on oS/X! */
         pathr[i-1]='\0';
       }
       i=strlen(pathr);
       if( i==0 ){
         printf("ERROR Empty parameter file name\n");
         goto end;
       }
       for (tok = pathr; tok != NULL; ){
         printf("Pathr |%s|\n",pathr);
         while ((val = strsep(&tok, "\"" )) != NULL && *val == '\0');
         printf("val= |%s| pathr=%s\n",val,pathr);
         strcpy (pathtot, val);
         if(pathr[0] == '\0') break; /* Dirty */
       }
     }
     else{
       strcpy(pathtot,argv[1]);
     }
     /*if(getcwd(pathcd, MAXLINE)!= NULL)printf ("Error pathcd\n");*/
     /*cygwin_split_path(pathtot,path,optionfile);
       printf("pathtot=%s, path=%s, optionfile=%s\n",pathtot,path,optionfile);*/
     /* cutv(path,optionfile,pathtot,'\\');*/
   
     /* Split argv[0], imach program to get pathimach */
     printf("\nargv[0]=%s argv[1]=%s, \n",argv[0],argv[1]);
     split(argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
     printf("\nargv[0]=%s pathimach=%s, \noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",argv[0],pathimach,optionfile,optionfilext,optionfilefiname);
    /*   strcpy(pathimach,argv[0]); */
     /* Split argv[1]=pathtot, parameter file name to get path, optionfile, extension and name */
     split(pathtot,path,optionfile,optionfilext,optionfilefiname);
     printf("\npathtot=%s,\npath=%s,\noptionfile=%s \noptionfilext=%s \noptionfilefiname=%s\n",pathtot,path,optionfile,optionfilext,optionfilefiname);
   #ifdef WIN32
     _chdir(path); /* Can be a relative path */
     if(_getcwd(pathcd,MAXLINE) > 0) /* So pathcd is the full path */
   #else
     chdir(path); /* Can be a relative path */
     if (getcwd(pathcd, MAXLINE) > 0) /* So pathcd is the full path */
   #endif
     printf("Current directory %s!\n",pathcd);
     strcpy(command,"mkdir ");
     strcat(command,optionfilefiname);
     if((outcmd=system(command)) != 0){
       printf("Directory already exists (or can't create it) %s%s, err=%d\n",path,optionfilefiname,outcmd);
       /* fprintf(ficlog,"Problem creating directory %s%s\n",path,optionfilefiname); */
       /* fclose(ficlog); */
   /*     exit(1); */
     }
   /*   if((imk=mkdir(optionfilefiname))<0){ */
   /*     perror("mkdir"); */
   /*   } */
   
     /*-------- arguments in the command line --------*/
   
     /* Main Log file */
     strcat(filelog, optionfilefiname);
     strcat(filelog,".log");    /* */
     if((ficlog=fopen(filelog,"w"))==NULL)    {
       printf("Problem with logfile %s\n",filelog);
       goto end;
     }
     fprintf(ficlog,"Log filename:%s\n",filelog);
     fprintf(ficlog,"Version %s %s",version,fullversion);
     fprintf(ficlog,"\nEnter the parameter file name: \n");
     fprintf(ficlog,"pathimach=%s\npathtot=%s\n\
    path=%s \n\
    optionfile=%s\n\
    optionfilext=%s\n\
    optionfilefiname='%s'\n",pathimach,pathtot,path,optionfile,optionfilext,optionfilefiname);
   
     syscompilerinfo(1);
   
     printf("Local time (at start):%s",strstart);
     fprintf(ficlog,"Local time (at start): %s",strstart);
     fflush(ficlog);
   /*   (void) gettimeofday(&curr_time,&tzp); */
   /*   printf("Elapsed time %d\n", asc_diff_time(curr_time.tm_sec-start_time.tm_sec,tmpout)); */
   
     /* */
     strcpy(fileres,"r");
     strcat(fileres, optionfilefiname);
     strcat(fileresu, optionfilefiname); /* Without r in front */
     strcat(fileres,".txt");    /* Other files have txt extension */
     strcat(fileresu,".txt");    /* Other files have txt extension */
   
     /* Main ---------arguments file --------*/
   
     if((ficpar=fopen(optionfile,"r"))==NULL)    {
       printf("Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
       fprintf(ficlog,"Problem with optionfile '%s' with errno='%s'\n",optionfile,strerror(errno));
       fflush(ficlog);
       /* goto end; */
       exit(70); 
     }
   
   
   
     strcpy(filereso,"o");
     strcat(filereso,fileresu);
     if((ficparo=fopen(filereso,"w"))==NULL) { /* opened on subdirectory */
       printf("Problem with Output resultfile: %s\n", filereso);
       fprintf(ficlog,"Problem with Output resultfile: %s\n", filereso);
       fflush(ficlog);
       goto end;
     }
   
     /* Reads comments: lines beginning with '#' */
     numlinepar=0;
   
       /* First parameter line */
     while(fgets(line, MAXLINE, ficpar)) {
       /* If line starts with a # it is a comment */
       if (line[0] == '#') {
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
         continue;
       }else
         break;
     }
     if((num_filled=sscanf(line,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", \
                           title, datafile, &lastobs, &firstpass,&lastpass)) !=EOF){
       if (num_filled != 5) {
         printf("Should be 5 parameters\n");
       }
       numlinepar++;
       printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\n", title, datafile, lastobs, firstpass,lastpass);
     }
     /* Second parameter line */
     while(fgets(line, MAXLINE, ficpar)) {
       /* If line starts with a # it is a comment */
       if (line[0] == '#') {
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
         continue;
       }else
         break;
     }
     if((num_filled=sscanf(line,"ftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n", \
                           &ftol, &stepm, &ncovcol, &nlstate, &ndeath, &maxwav, &mle, &weightopt)) !=EOF){
       if (num_filled != 8) {
         printf("Not 8 parameters, for example:ftol=1.e-8 stepm=12 ncovcol=2 nlstate=2 ndeath=1 maxwav=3 mle=1 weight=1\n");
         printf("but line=%s\n",line);
       }
       printf("ftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\n",ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt);
     }
     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
     /*ftolpl=6.e-4; *//* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
     /* Third parameter line */
     while(fgets(line, MAXLINE, ficpar)) {
       /* If line starts with a # it is a comment */
       if (line[0] == '#') {
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
         continue;
       }else
         break;
     }
     if((num_filled=sscanf(line,"model=1+age%[^.\n]", model)) !=EOF){
       if (num_filled == 0)
               model[0]='\0';
       else if (num_filled != 1){
         printf("ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
         fprintf(ficlog,"ERROR %d: Model should be at minimum 'model=1+age.' %s\n",num_filled, line);
         model[0]='\0';
         goto end;
       }
       else{
         if (model[0]=='+'){
           for(i=1; i<=strlen(model);i++)
             modeltemp[i-1]=model[i];
           strcpy(model,modeltemp); 
         }
       }
       /* printf(" model=1+age%s modeltemp= %s, model=%s\n",model, modeltemp, model);fflush(stdout); */
       printf("model=1+age+%s\n",model);fflush(stdout);
     }
     /* fscanf(ficpar,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%lf stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d model=1+age+%s\n",title, datafile, &lastobs, &firstpass,&lastpass,&ftol, &stepm, &ncovcol, &nlstate,&ndeath, &maxwav, &mle, &weightopt,model); */
     /* numlinepar=numlinepar+3; /\* In general *\/ */
     /* printf("title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate,ndeath, maxwav, mle, weightopt,model); */
     fprintf(ficparo,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
     fprintf(ficlog,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle=%d weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol,stepm,ncovcol,nlstate,ndeath,maxwav, mle, weightopt,model);
     fflush(ficlog);
     /* if(model[0]=='#'|| model[0]== '\0'){ */
     if(model[0]=='#'){
       printf("Error in 'model' line: model should start with 'model=1+age+' and end with '.' \n \
    'model=1+age+.' or 'model=1+age+V1.' or 'model=1+age+age*age+V1+V1*age.' or \n \
    'model=1+age+V1+V2.' or 'model=1+age+V1+V2+V1*V2.' etc. \n");          \
       if(mle != -1){
         printf("Fix the model line and run imach with mle=-1 to get a correct template of the parameter file.\n");
         exit(1);
       }
     }
     while((c=getc(ficpar))=='#' && c!= EOF){
       ungetc(c,ficpar);
       fgets(line, MAXLINE, ficpar);
       numlinepar++;
       if(line[1]=='q'){ /* This #q will quit imach (the answer is q) */
         z[0]=line[1];
       }
       /* printf("****line [1] = %c \n",line[1]); */
       fputs(line, stdout);
       //puts(line);
       fputs(line,ficparo);
       fputs(line,ficlog);
     }
     ungetc(c,ficpar);
   
      
     covar=matrix(0,NCOVMAX,1,n);  /**< used in readdata */
     cptcovn=0; /*Number of covariates, i.e. number of '+' in model statement plus one, indepently of n in Vn*/
     /* v1+v2+v3+v2*v4+v5*age makes cptcovn = 5
        v1+v2*age+v2*v3 makes cptcovn = 3
     */
     if (strlen(model)>1) 
       ncovmodel=2+nbocc(model,'+')+1; /*Number of variables including intercept and age = cptcovn + intercept + age : v1+v2+v3+v2*v4+v5*age makes 5+2=7,age*age makes 3*/
     else
       ncovmodel=2; /* Constant and age */
     nforce= (nlstate+ndeath-1)*nlstate; /* Number of forces ij from state i to j */
     npar= nforce*ncovmodel; /* Number of parameters like aij*/
     if(npar >MAXPARM || nlstate >NLSTATEMAX || ndeath >NDEATHMAX || ncovmodel>NCOVMAX){
       printf("Too complex model for current IMaCh: npar=(nlstate+ndeath-1)*nlstate*ncovmodel=%d >= %d(MAXPARM) or nlstate=%d >= %d(NLSTATEMAX) or ndeath=%d >= %d(NDEATHMAX) or ncovmodel=(k+age+#of+signs)=%d(NCOVMAX) >= %d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
       fprintf(ficlog,"Too complex model for current IMaCh: %d >=%d(MAXPARM) or %d >=%d(NLSTATEMAX) or %d >=%d(NDEATHMAX) or %d(NCOVMAX) >=%d\n",npar, MAXPARM, nlstate, NLSTATEMAX, ndeath, NDEATHMAX, ncovmodel, NCOVMAX);
       fflush(stdout);
       fclose (ficlog);
       goto end;
     }
     delti3= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
     delti=delti3[1][1];
     /*delti=vector(1,npar); *//* Scale of each paramater (output from hesscov)*/
     if(mle==-1){ /* Print a wizard for help writing covariance matrix */
       prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
       printf(" You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
       fprintf(ficlog," You chose mle=-1, look at file %s for a template of covariance matrix \n",filereso);
       free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
       fclose (ficparo);
       fclose (ficlog);
       goto end;
       exit(0);
     }
     else if(mle==-3) { /* Main Wizard */
       prwizard(ncovmodel, nlstate, ndeath, model, ficparo);
       printf(" You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
       fprintf(ficlog," You chose mle=-3, look at file %s for a template of covariance matrix \n",filereso);
       param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
       matcov=matrix(1,npar,1,npar);
       hess=matrix(1,npar,1,npar);
     }
     else{
       /* Read guessed parameters */
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
       
       param= ma3x(1,nlstate,1,nlstate+ndeath-1,1,ncovmodel);
       for(i=1; i <=nlstate; i++){
         j=0;
         for(jj=1; jj <=nlstate+ndeath; jj++){
           if(jj==i) continue;
           j++;
           fscanf(ficpar,"%1d%1d",&i1,&j1);
           if ((i1 != i) || (j1 != jj)){
             printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n \
   It might be a problem of design; if ncovcol and the model are correct\n \
   run imach with mle=-1 to get a correct template of the parameter file.\n",numlinepar, i,j, i1, j1);
             exit(1);
           }
           fprintf(ficparo,"%1d%1d",i1,j1);
           if(mle==1)
             printf("%1d%1d",i,jj);
           fprintf(ficlog,"%1d%1d",i,jj);
           for(k=1; k<=ncovmodel;k++){
             fscanf(ficpar," %lf",&param[i][j][k]);
             if(mle==1){
               printf(" %lf",param[i][j][k]);
               fprintf(ficlog," %lf",param[i][j][k]);
             }
             else
               fprintf(ficlog," %lf",param[i][j][k]);
             fprintf(ficparo," %lf",param[i][j][k]);
           }
           fscanf(ficpar,"\n");
           numlinepar++;
           if(mle==1)
             printf("\n");
           fprintf(ficlog,"\n");
           fprintf(ficparo,"\n");
         }
       }  
       fflush(ficlog);
   
       /* Reads scales values */
       p=param[1][1];
       
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
   
       for(i=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath-1; j++){
           fscanf(ficpar,"%1d%1d",&i1,&j1);
           if ( (i1-i) * (j1-j) != 0){
             printf("Error in line parameters number %d, %1d%1d instead of %1d%1d \n",numlinepar, i,j, i1, j1);
             exit(1);
           }
           printf("%1d%1d",i,j);
           fprintf(ficparo,"%1d%1d",i1,j1);
           fprintf(ficlog,"%1d%1d",i1,j1);
           for(k=1; k<=ncovmodel;k++){
             fscanf(ficpar,"%le",&delti3[i][j][k]);
             printf(" %le",delti3[i][j][k]);
             fprintf(ficparo," %le",delti3[i][j][k]);
             fprintf(ficlog," %le",delti3[i][j][k]);
           }
           fscanf(ficpar,"\n");
           numlinepar++;
           printf("\n");
           fprintf(ficparo,"\n");
           fprintf(ficlog,"\n");
         }
       }
       fflush(ficlog);
   
       /* Reads covariance matrix */
       delti=delti3[1][1];
   
   
       /* free_ma3x(delti3,1,nlstate,1,nlstate+ndeath-1,1,ncovmodel); */ /* Hasn't to to freed here otherwise delti is no more allocated */
     
       /* Reads comments: lines beginning with '#' */
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
       }
       ungetc(c,ficpar);
     
       matcov=matrix(1,npar,1,npar);
       hess=matrix(1,npar,1,npar);
       for(i=1; i <=npar; i++)
         for(j=1; j <=npar; j++) matcov[i][j]=0.;
         
       /* Scans npar lines */
       for(i=1; i <=npar; i++){
         count=fscanf(ficpar,"%1d%1d%1d",&i1,&j1,&jk);
         if(count != 3){
           printf("Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
   This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
   Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
           fprintf(ficlog,"Error! Error in parameter file %s at line %d after line starting with %1d%1d%1d\n\
   This is probably because your covariance matrix doesn't \n  contain exactly %d lines corresponding to your model line '1+age+%s'.\n\
   Please run with mle=-1 to get a correct covariance matrix.\n",optionfile,numlinepar, i1,j1,jk, npar, model);
           exit(1);
         }else
         if(mle==1)
           printf("%1d%1d%1d",i1,j1,jk);
         fprintf(ficlog,"%1d%1d%1d",i1,j1,jk);
         fprintf(ficparo,"%1d%1d%1d",i1,j1,jk);
         for(j=1; j <=i; j++){
           fscanf(ficpar," %le",&matcov[i][j]);
           if(mle==1){
             printf(" %.5le",matcov[i][j]);
           }
           fprintf(ficlog," %.5le",matcov[i][j]);
           fprintf(ficparo," %.5le",matcov[i][j]);
         }
         fscanf(ficpar,"\n");
         numlinepar++;
         if(mle==1)
           printf("\n");
         fprintf(ficlog,"\n");
         fprintf(ficparo,"\n");
       }
       /* End of read covariance matrix npar lines */
       for(i=1; i <=npar; i++)
         for(j=i+1;j<=npar;j++)
           matcov[i][j]=matcov[j][i];
       
       if(mle==1)
         printf("\n");
       fprintf(ficlog,"\n");
       
       fflush(ficlog);
       
       /*-------- Rewriting parameter file ----------*/
       strcpy(rfileres,"r");    /* "Rparameterfile */
       strcat(rfileres,optionfilefiname);    /* Parameter file first name*/
       strcat(rfileres,".");    /* */
       strcat(rfileres,optionfilext);    /* Other files have txt extension */
       if((ficres =fopen(rfileres,"w"))==NULL) {
         printf("Problem writing new parameter file: %s\n", rfileres);goto end;
         fprintf(ficlog,"Problem writing new parameter file: %s\n", rfileres);goto end;
       }
       fprintf(ficres,"#%s\n",version);
     }    /* End of mle != -3 */
   
     /*  Main data
      */
     n= lastobs;
     num=lvector(1,n);
     moisnais=vector(1,n);
     annais=vector(1,n);
     moisdc=vector(1,n);
     andc=vector(1,n);
     agedc=vector(1,n);
     cod=ivector(1,n);
     weight=vector(1,n);
     for(i=1;i<=n;i++) weight[i]=1.0; /* Equal weights, 1 by default */
     mint=matrix(1,maxwav,1,n);
     anint=matrix(1,maxwav,1,n);
     s=imatrix(1,maxwav+1,1,n); /* s[i][j] health state for wave i and individual j */ 
     tab=ivector(1,NCOVMAX);
     ncodemax=ivector(1,NCOVMAX); /* Number of code per covariate; if O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
     ncodemaxwundef=ivector(1,NCOVMAX); /* Number of code per covariate; if - 1 O and 1 only, 2**ncov; V1+V2+V3+V4=>16 */
   
     /* Reads data from file datafile */
     if (readdata(datafile, firstobs, lastobs, &imx)==1)
       goto end;
   
     /* Calculation of the number of parameters from char model */
       /*    modelsav=V2+V1+V4+age*V3 strb=age*V3 stra=V2+V1+V4 
           k=4 (age*V3) Tvar[k=4]= 3 (from V3) Tag[cptcovage=1]=4
           k=3 V4 Tvar[k=3]= 4 (from V4)
           k=2 V1 Tvar[k=2]= 1 (from V1)
           k=1 Tvar[1]=2 (from V2)
       */
     Tvar=ivector(1,NCOVMAX); /* Was 15 changed to NCOVMAX. */
     /*  V2+V1+V4+age*V3 is a model with 4 covariates (3 plus signs). 
         For each model-covariate stores the data-covariate id. Tvar[1]=2, Tvar[2]=1, Tvar[3]=4, 
         Tvar[4=age*V3] is 3 and 'age' is recorded in Tage.
     */
     /* For model-covariate k tells which data-covariate to use but
       because this model-covariate is a construction we invent a new column
       ncovcol + k1
       If already ncovcol=4 and model=V2+V1+V1*V4+age*V3
       Tvar[3=V1*V4]=4+1 etc */
     Tprod=ivector(1,NCOVMAX); /* Gives the position of a product */
     /* Tprod[k1=1]=3(=V1*V4) for V2+V1+V1*V4+age*V3
        if  V2+V1+V1*V4+age*V3+V3*V2   TProd[k1=2]=5 (V3*V2)
     */
     Tvaraff=ivector(1,NCOVMAX); /* Unclear */
     Tvard=imatrix(1,NCOVMAX,1,2); /* n=Tvard[k1][1]  and m=Tvard[k1][2] gives the couple n,m of the k1 th product Vn*Vm
                               * For V3*V2 (in V2+V1+V1*V4+age*V3+V3*V2), V3*V2 position is 2nd. 
                               * Tvard[k1=2][1]=3 (V3) Tvard[k1=2][2]=2(V2) */
     Tage=ivector(1,NCOVMAX); /* Gives the covariate id of covariates associated with age: V2 + V1 + age*V4 + V3*age
                            4 covariates (3 plus signs)
                            Tage[1=V3*age]= 4; Tage[2=age*V4] = 3
                         */  
   
   /* Main decodemodel */
   
   
     if(decodemodel(model, lastobs) == 1)
       goto end;
   
     if((double)(lastobs-imx)/(double)imx > 1.10){
       nbwarn++;
       printf("Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
       fprintf(ficlog,"Warning: The value of parameter lastobs=%d is big compared to the \n  effective number of cases imx=%d, please adjust, \n  otherwise you are allocating more memory than necessary.\n",lastobs, imx); 
     }
       /*  if(mle==1){*/
     if (weightopt != 1) { /* Maximisation without weights. We can have weights different from 1 but want no weight*/
       for(i=1;i<=imx;i++) weight[i]=1.0; /* changed to imx */
     }
   
       /*-calculation of age at interview from date of interview and age at death -*/
     agev=matrix(1,maxwav,1,imx);
   
     if(calandcheckages(imx, maxwav, &agemin, &agemax, &nberr, &nbwarn) == 1)
       goto end;
   
   
     agegomp=(int)agemin;
     free_vector(moisnais,1,n);
     free_vector(annais,1,n);
     /* free_matrix(mint,1,maxwav,1,n);
        free_matrix(anint,1,maxwav,1,n);*/
     free_vector(moisdc,1,n);
     free_vector(andc,1,n);
     /* */
     
     wav=ivector(1,imx);
     dh=imatrix(1,lastpass-firstpass+1,1,imx);
     bh=imatrix(1,lastpass-firstpass+1,1,imx);
     mw=imatrix(1,lastpass-firstpass+1,1,imx);
      
     /* Concatenates waves */
     concatwav(wav, dh, bh, mw, s, agedc, agev,  firstpass, lastpass, imx, nlstate, stepm);
     /* */
    
     /* Routine tricode is to calculate cptcoveff (real number of unique covariates) and to associate covariable number and modality */
   
     nbcode=imatrix(0,NCOVMAX,0,NCOVMAX); 
     ncodemax[1]=1;
     Ndum =ivector(-1,NCOVMAX);  
     if (ncovmodel-nagesqr > 2 ) /* That is if covariate other than cst, age and age*age */
       tricode(Tvar,nbcode,imx, Ndum); /**< Fills nbcode[Tvar[j]][l]; */
     /* Nbcode gives the value of the lth modality of jth covariate, in
        V2+V1*age, there are 3 covariates Tvar[2]=1 (V1).*/
     /* 1 to ncodemax[j] is the maximum value of this jth covariate */
   
     /*  codtab=imatrix(1,100,1,10);*/ /* codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) */
     /*printf(" codtab[1,1],codtab[100,10]=%d,%d\n", codtab[1][1],codtabm(100,10));*/
     /* codtab gives the value 1 or 2 of the hth combination of k covariates (1 or 2).*/
     h=0;
   
   
     /*if (cptcovn > 0) */
         
    
     m=pow(2,cptcoveff);
    
             /**< codtab(h,k)  k   = codtab[h,k]=( (h-1) - mod(k-1,2**(k-1) )/2**(k-1) + 1
              * For k=4 covariates, h goes from 1 to 2**k
              * codtabm(h,k)=  1 & (h-1) >> (k-1) ;
              *     h\k   1     2     3     4
              *______________________________  
              *     1 i=1 1 i=1 1 i=1 1 i=1 1
              *     2     2     1     1     1
              *     3 i=2 1     2     1     1
              *     4     2     2     1     1
              *     5 i=3 1 i=2 1     2     1
              *     6     2     1     2     1
              *     7 i=4 1     2     2     1
              *     8     2     2     2     1
              *     9 i=5 1 i=3 1 i=2 1     2
              *    10     2     1     1     2
              *    11 i=6 1     2     1     2
              *    12     2     2     1     2
              *    13 i=7 1 i=4 1     2     2    
              *    14     2     1     2     2
              *    15 i=8 1     2     2     2
              *    16     2     2     2     2
              */
     /* /\* for(h=1; h <=100 ;h++){  *\/ */
     /*   /\* printf("h=%2d ", h); *\/ */
     /*    /\* for(k=1; k <=10; k++){ *\/ */
     /*      /\* printf("k=%d %d ",k,codtabm(h,k)); *\/ */
     /*    /\*   codtab[h][k]=codtabm(h,k); *\/ */
     /*    /\* } *\/ */
     /*    /\* printf("\n"); *\/ */
     /* } */
     /* for(k=1;k<=cptcoveff; k++){ /\* scans any effective covariate *\/ */
     /*   for(i=1; i <=pow(2,cptcoveff-k);i++){ /\* i=1 to 8/1=8; i=1 to 8/2=4; i=1 to 8/8=1 *\/  */
     /*     for(j=1; j <= ncodemax[k]; j++){ /\* For each modality of this covariate ncodemax=2*\/ */
     /*    for(cpt=1; cpt <=pow(2,k-1); cpt++){  /\* cpt=1 to 8/2**(3+1-1 or 3+1-3) =1 or 4 *\/  */
     /*      h++; */
     /*      if (h>m)  */
     /*        h=1; */
     /*      codtab[h][k]=j; */
     /*      /\* codtab[12][3]=1; *\/ */
     /*      /\*codtab[h][Tvar[k]]=j;*\/ */
     /*      /\* printf("h=%d k=%d j=%d codtab[h][k]=%d Tvar[k]=%d codtab[h][Tvar[k]]=%d \n",h, k,j,codtab[h][k],Tvar[k],codtab[h][Tvar[k]]); *\/ */
     /*    }  */
     /*     } */
     /*   } */
     /* }  */
     /* printf("codtab[1][2]=%d codtab[2][2]=%d",codtab[1][2],codtab[2][2]); 
        codtab[1][2]=1;codtab[2][2]=2; */
     /* for(i=1; i <=m ;i++){  */
     /*    for(k=1; k <=cptcovn; k++){ */
     /*      printf("i=%d k=%d %d %d ",i,k,codtab[i][k], cptcoveff); */
     /*    } */
     /*    printf("\n"); */
     /* } */
     /*   scanf("%d",i);*/
   
    free_ivector(Ndum,-1,NCOVMAX);
   
   
       
     /* Initialisation of ----------- gnuplot -------------*/
     strcpy(optionfilegnuplot,optionfilefiname);
     if(mle==-3)
       strcat(optionfilegnuplot,"-MORT_");
     strcat(optionfilegnuplot,".gp");
   
     if((ficgp=fopen(optionfilegnuplot,"w"))==NULL) {
       printf("Problem with file %s",optionfilegnuplot);
     }
     else{
       fprintf(ficgp,"\n# IMaCh-%s\n", version); 
       fprintf(ficgp,"# %s\n", optionfilegnuplot); 
       //fprintf(ficgp,"set missing 'NaNq'\n");
       fprintf(ficgp,"set datafile missing 'NaNq'\n");
     }
     /*  fclose(ficgp);*/
   
   
     /* Initialisation of --------- index.htm --------*/
   
     strcpy(optionfilehtm,optionfilefiname); /* Main html file */
     if(mle==-3)
       strcat(optionfilehtm,"-MORT_");
     strcat(optionfilehtm,".htm");
     if((fichtm=fopen(optionfilehtm,"w"))==NULL)    {
       printf("Problem with %s \n",optionfilehtm);
       exit(0);
     }
   
     strcpy(optionfilehtmcov,optionfilefiname); /* Only for matrix of covariance */
     strcat(optionfilehtmcov,"-cov.htm");
     if((fichtmcov=fopen(optionfilehtmcov,"w"))==NULL)    {
       printf("Problem with %s \n",optionfilehtmcov), exit(0);
     }
     else{
     fprintf(fichtmcov,"<html><head>\n<title>IMaCh Cov %s</title></head>\n <body><font size=\"2\">%s <br> %s</font> \
   <hr size=\"2\" color=\"#EC5E5E\"> \n\
   Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n",\
             optionfilehtmcov,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model);
     }
   
     fprintf(fichtm,"<html><head>\n<head>\n<meta charset=\"utf-8\"/><meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<title>IMaCh %s</title></head>\n <body><font size=\"7\"><a href=http:/euroreves.ined.fr/imach>IMaCh for Interpolated Markov Chain</a> </font><br>\n<font size=\"3\">Sponsored by Copyright (C)  2002-2015 <a href=http://www.ined.fr>INED</a>-EUROREVES-Institut de longévité-Japan Society for the Promotion of Sciences 日本学術振興会 (<a href=https://www.jsps.go.jp/english/e-grants/>Grant-in-Aid for Scientific Research 25293121</a>) - <a href=https://software.intel.com/en-us>Intel Software 2015</a></font><br>  \
   <hr size=\"2\" color=\"#EC5E5E\"> \n\
   <font size=\"2\">IMaCh-%s <br> %s</font> \
   <hr size=\"2\" color=\"#EC5E5E\"> \n\
   Title=%s <br>Datafile=%s Firstpass=%d Lastpass=%d Stepm=%d Weight=%d Model=1+age+%s<br>\n\
   \n\
   <hr  size=\"2\" color=\"#EC5E5E\">\
    <ul><li><h4>Parameter files</h4>\n\
    - Parameter file: <a href=\"%s.%s\">%s.%s</a><br>\n\
    - Copy of the parameter file: <a href=\"o%s\">o%s</a><br>\n\
    - Log file of the run: <a href=\"%s\">%s</a><br>\n\
    - Gnuplot file name: <a href=\"%s\">%s</a><br>\n\
    - Date and time at start: %s</ul>\n",\
             optionfilehtm,version,fullversion,title,datafile,firstpass,lastpass,stepm, weightopt, model,\
             optionfilefiname,optionfilext,optionfilefiname,optionfilext,\
             fileres,fileres,\
             filelog,filelog,optionfilegnuplot,optionfilegnuplot,strstart);
     fflush(fichtm);
   
     strcpy(pathr,path);
     strcat(pathr,optionfilefiname);
   #ifdef WIN32
     _chdir(optionfilefiname); /* Move to directory named optionfile */
   #else
     chdir(optionfilefiname); /* Move to directory named optionfile */
   #endif
             
     
     /* Calculates basic frequencies. Computes observed prevalence at single age
        and prints on file fileres'p'. */
     freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint,strstart);
   
     fprintf(fichtm,"\n");
     fprintf(fichtm,"<br>Total number of observations=%d <br>\n\
   Youngest age at first (selected) pass %.2f, oldest age %.2f<br>\n\
   Interval (in months) between two waves: Min=%d Max=%d Mean=%.2lf<br>\n",\
             imx,agemin,agemax,jmin,jmax,jmean);
     pmmij= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       oldms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       newms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       savms= matrix(1,nlstate+ndeath,1,nlstate+ndeath); /* creation */
       oldm=oldms; newm=newms; savm=savms; /* Keeps fixed addresses to free */
       
      
     /* For Powell, parameters are in a vector p[] starting at p[1]
        so we point p on param[1][1] so that p[1] maps on param[1][1][1] */
     p=param[1][1]; /* *(*(*(param +1)+1)+0) */
   
     globpr=0; /* To get the number ipmx of contributions and the sum of weights*/
     /* For mortality only */
     if (mle==-3){
       ximort=matrix(1,NDIM,1,NDIM); 
       /*     ximort=gsl_matrix_alloc(1,NDIM,1,NDIM); */
       cens=ivector(1,n);
       ageexmed=vector(1,n);
       agecens=vector(1,n);
       dcwave=ivector(1,n);
    
       for (i=1; i<=imx; i++){
         dcwave[i]=-1;
         for (m=firstpass; m<=lastpass; m++)
           if (s[m][i]>nlstate) {
             dcwave[i]=m;
             /*    printf("i=%d j=%d s=%d dcwave=%d\n",i,j, s[j][i],dcwave[i]);*/
             break;
           }
       }
   
       for (i=1; i<=imx; i++) {
         if (wav[i]>0){
           ageexmed[i]=agev[mw[1][i]][i];
           j=wav[i];
           agecens[i]=1.; 
   
           if (ageexmed[i]> 1 && wav[i] > 0){
             agecens[i]=agev[mw[j][i]][i];
             cens[i]= 1;
           }else if (ageexmed[i]< 1) 
             cens[i]= -1;
           if (agedc[i]< AGESUP && agedc[i]>1 && dcwave[i]>firstpass && dcwave[i]<=lastpass)
             cens[i]=0 ;
         }
         else cens[i]=-1;
       }
       
       for (i=1;i<=NDIM;i++) {
         for (j=1;j<=NDIM;j++)
           ximort[i][j]=(i == j ? 1.0 : 0.0);
       }
       
       /*p[1]=0.0268; p[NDIM]=0.083;*/
       /*printf("%lf %lf", p[1], p[2]);*/
       
       
   #ifdef GSL
       printf("GSL optimization\n");  fprintf(ficlog,"Powell\n");
   #else
       printf("Powell\n");  fprintf(ficlog,"Powell\n");
   #endif
       strcpy(filerespow,"POW-MORT_"); 
       strcat(filerespow,fileresu);
       if((ficrespow=fopen(filerespow,"w"))==NULL) {
         printf("Problem with resultfile: %s\n", filerespow);
         fprintf(ficlog,"Problem with resultfile: %s\n", filerespow);
       }
   #ifdef GSL
       fprintf(ficrespow,"# GSL optimization\n# iter -2*LL");
   #else
       fprintf(ficrespow,"# Powell\n# iter -2*LL");
   #endif
       /*  for (i=1;i<=nlstate;i++)
           for(j=1;j<=nlstate+ndeath;j++)
           if(j!=i)fprintf(ficrespow," p%1d%1d",i,j);
       */
       fprintf(ficrespow,"\n");
   #ifdef GSL
       /* gsl starts here */ 
       T = gsl_multimin_fminimizer_nmsimplex;
       gsl_multimin_fminimizer *sfm = NULL;
       gsl_vector *ss, *x;
       gsl_multimin_function minex_func;
   
       /* Initial vertex size vector */
       ss = gsl_vector_alloc (NDIM);
       
       if (ss == NULL){
         GSL_ERROR_VAL ("failed to allocate space for ss", GSL_ENOMEM, 0);
       }
       /* Set all step sizes to 1 */
       gsl_vector_set_all (ss, 0.001);
   
       /* Starting point */
       
       x = gsl_vector_alloc (NDIM);
       
       if (x == NULL){
         gsl_vector_free(ss);
         GSL_ERROR_VAL ("failed to allocate space for x", GSL_ENOMEM, 0);
       }
     
       /* Initialize method and iterate */
       /*     p[1]=0.0268; p[NDIM]=0.083; */
       /*     gsl_vector_set(x, 0, 0.0268); */
       /*     gsl_vector_set(x, 1, 0.083); */
       gsl_vector_set(x, 0, p[1]);
       gsl_vector_set(x, 1, p[2]);
   
       minex_func.f = &gompertz_f;
       minex_func.n = NDIM;
       minex_func.params = (void *)&p; /* ??? */
       
       sfm = gsl_multimin_fminimizer_alloc (T, NDIM);
       gsl_multimin_fminimizer_set (sfm, &minex_func, x, ss);
       
       printf("Iterations beginning .....\n\n");
       printf("Iter. #    Intercept       Slope     -Log Likelihood     Simplex size\n");
   
       iteri=0;
       while (rval == GSL_CONTINUE){
         iteri++;
         status = gsl_multimin_fminimizer_iterate(sfm);
         
         if (status) printf("error: %s\n", gsl_strerror (status));
         fflush(0);
         
         if (status) 
           break;
         
         rval = gsl_multimin_test_size (gsl_multimin_fminimizer_size (sfm), 1e-6);
         ssval = gsl_multimin_fminimizer_size (sfm);
         
         if (rval == GSL_SUCCESS)
           printf ("converged to a local maximum at\n");
         
         printf("%5d ", iteri);
         for (it = 0; it < NDIM; it++){
           printf ("%10.5f ", gsl_vector_get (sfm->x, it));
         }
         printf("f() = %-10.5f ssize = %.7f\n", sfm->fval, ssval);
       }
       
       printf("\n\n Please note: Program should be run many times with varying starting points to detemine global maximum\n\n");
       
       gsl_vector_free(x); /* initial values */
       gsl_vector_free(ss); /* inital step size */
       for (it=0; it<NDIM; it++){
         p[it+1]=gsl_vector_get(sfm->x,it);
         fprintf(ficrespow," %.12lf", p[it]);
       }
       gsl_multimin_fminimizer_free (sfm); /* p *(sfm.x.data) et p *(sfm.x.data+1)  */
   #endif
   #ifdef POWELL
        powell(p,ximort,NDIM,ftol,&iter,&fret,gompertz);
   #endif  
       fclose(ficrespow);
       
       hesscov(matcov, hess, p, NDIM, delti, 1e-4, gompertz); 
   
       for(i=1; i <=NDIM; i++)
         for(j=i+1;j<=NDIM;j++)
           matcov[i][j]=matcov[j][i];
       
       printf("\nCovariance matrix\n ");
       fprintf(ficlog,"\nCovariance matrix\n ");
       for(i=1; i <=NDIM; i++) {
         for(j=1;j<=NDIM;j++){ 
           printf("%f ",matcov[i][j]);
           fprintf(ficlog,"%f ",matcov[i][j]);
         }
         printf("\n ");  fprintf(ficlog,"\n ");
       }
       
       printf("iter=%d MLE=%f Eq=%lf*exp(%lf*(age-%d))\n",iter,-gompertz(p),p[1],p[2],agegomp);
       for (i=1;i<=NDIM;i++) {
         printf("%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
         fprintf(ficlog,"%f [%f ; %f]\n",p[i],p[i]-2*sqrt(matcov[i][i]),p[i]+2*sqrt(matcov[i][i]));
       }
       lsurv=vector(1,AGESUP);
       lpop=vector(1,AGESUP);
       tpop=vector(1,AGESUP);
       lsurv[agegomp]=100000;
       
       for (k=agegomp;k<=AGESUP;k++) {
         agemortsup=k;
         if (p[1]*exp(p[2]*(k-agegomp))>1) break;
       }
       
       for (k=agegomp;k<agemortsup;k++)
         lsurv[k+1]=lsurv[k]-lsurv[k]*(p[1]*exp(p[2]*(k-agegomp)));
       
       for (k=agegomp;k<agemortsup;k++){
         lpop[k]=(lsurv[k]+lsurv[k+1])/2.;
         sumlpop=sumlpop+lpop[k];
       }
       
       tpop[agegomp]=sumlpop;
       for (k=agegomp;k<(agemortsup-3);k++){
         /*  tpop[k+1]=2;*/
         tpop[k+1]=tpop[k]-lpop[k];
       }
       
       
       printf("\nAge   lx     qx    dx    Lx     Tx     e(x)\n");
       for (k=agegomp;k<(agemortsup-2);k++) 
         printf("%d %.0lf %lf %.0lf %.0lf %.0lf %lf\n",k,lsurv[k],p[1]*exp(p[2]*(k-agegomp)),(p[1]*exp(p[2]*(k-agegomp)))*lsurv[k],lpop[k],tpop[k],tpop[k]/lsurv[k]);
       
       
       replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
       if(ageminpar == AGEOVERFLOW ||agemaxpar == AGEOVERFLOW){
           printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
   This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
   Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
           fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
   This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
   Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
       }else
         printinggnuplotmort(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
       printinghtmlmort(fileresu,title,datafile, firstpass, lastpass, \
                        stepm, weightopt,\
                        model,imx,p,matcov,agemortsup);
       
       free_vector(lsurv,1,AGESUP);
       free_vector(lpop,1,AGESUP);
       free_vector(tpop,1,AGESUP);
   #ifdef GSL
       free_ivector(cens,1,n);
       free_vector(agecens,1,n);
       free_ivector(dcwave,1,n);
       free_matrix(ximort,1,NDIM,1,NDIM);
   #endif
     } /* Endof if mle==-3 mortality only */
     /* Standard  */
     else{ /* For mle !=- 3, could be 0 or 1 or 4 etc. */
       globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
       /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
       printf("First Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
       for (k=1; k<=npar;k++)
         printf(" %d %8.5f",k,p[k]);
       printf("\n");
       if(mle>=1){ /* Could be 1 or 2, Real Maximization */
         /* mlikeli uses func not funcone */
         mlikeli(ficres,p, npar, ncovmodel, nlstate, ftol, func);
       }
       if(mle==0) {/* No optimization, will print the likelihoods for the datafile */
         globpr=0;/* Computes sum of likelihood for globpr=1 and funcone */
         /* Computes likelihood for initial parameters, uses funcone to compute gpimx and gsw */
         likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
       }
       globpr=1; /* again, to print the individual contributions using computed gpimx and gsw */
       likelione(ficres, p, npar, nlstate, &globpr, &ipmx, &sw, &fretone, funcone); /* Prints the contributions to the likelihood */
       printf("Second Likeli=%12.6f ipmx=%ld sw=%12.6f",fretone,ipmx,sw);
       for (k=1; k<=npar;k++)
         printf(" %d %8.5f",k,p[k]);
       printf("\n");
       
       /*--------- results files --------------*/
       fprintf(ficres,"title=%s datafile=%s lastobs=%d firstpass=%d lastpass=%d\nftol=%e stepm=%d ncovcol=%d nlstate=%d ndeath=%d maxwav=%d mle= 0 weight=%d\nmodel=1+age+%s.\n", title, datafile, lastobs, firstpass,lastpass,ftol, stepm, ncovcol, nlstate, ndeath, maxwav, weightopt,model);
       
       
       fprintf(ficres,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       printf("# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       fprintf(ficlog,"# Parameters nlstate*nlstate*ncov a12*1 + b12 * age + ...\n");
       for(i=1,jk=1; i <=nlstate; i++){
         for(k=1; k <=(nlstate+ndeath); k++){
           if (k != i) {
             printf("%d%d ",i,k);
             fprintf(ficlog,"%d%d ",i,k);
             fprintf(ficres,"%1d%1d ",i,k);
             for(j=1; j <=ncovmodel; j++){
               printf("%12.7f ",p[jk]);
               fprintf(ficlog,"%12.7f ",p[jk]);
               fprintf(ficres,"%12.7f ",p[jk]);
               jk++; 
             }
             printf("\n");
             fprintf(ficlog,"\n");
             fprintf(ficres,"\n");
           }
         }
       }
       if(mle != 0){
         /* Computing hessian and covariance matrix only at a peak of the Likelihood, that is after optimization */
         ftolhess=ftol; /* Usually correct */
         hesscov(matcov, hess, p, npar, delti, ftolhess, func);
         printf("Parameters and 95%% confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W .\n But be careful that parameters are highly correlated because incidence of disability is highly correlated to incidence of recovery.\n It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
         fprintf(ficlog, "Parameters, Wald tests and Wald-based confidence intervals\n W is simply the result of the division of the parameter by the square root of covariance of the parameter.\n And Wald-based confidence intervals plus and minus 1.96 * W \n  It might be better to visualize the covariance matrix. See the page 'Matrix of variance-covariance of one-step probabilities' and its graphs.\n");
         for(i=1,jk=1; i <=nlstate; i++){
           for(k=1; k <=(nlstate+ndeath); k++){
             if (k != i) {
               printf("%d%d ",i,k);
               fprintf(ficlog,"%d%d ",i,k);
               for(j=1; j <=ncovmodel; j++){
                 printf("%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                 fprintf(ficlog,"%12.7f W=%8.3f CI=[%12.7f ; %12.7f] ",p[jk], p[jk]/sqrt(matcov[jk][jk]), p[jk]-1.96*sqrt(matcov[jk][jk]),p[jk]+1.96*sqrt(matcov[jk][jk]));
                 jk++; 
               }
               printf("\n");
               fprintf(ficlog,"\n");
             }
           }
         }
       } /* end of hesscov and Wald tests */
   
       /*  */
       fprintf(ficres,"# Scales (for hessian or gradient estimation)\n");
       printf("# Scales (for hessian or gradient estimation)\n");
       fprintf(ficlog,"# Scales (for hessian or gradient estimation)\n");
       for(i=1,jk=1; i <=nlstate; i++){
         for(j=1; j <=nlstate+ndeath; j++){
           if (j!=i) {
             fprintf(ficres,"%1d%1d",i,j);
             printf("%1d%1d",i,j);
             fprintf(ficlog,"%1d%1d",i,j);
             for(k=1; k<=ncovmodel;k++){
               printf(" %.5e",delti[jk]);
               fprintf(ficlog," %.5e",delti[jk]);
               fprintf(ficres," %.5e",delti[jk]);
               jk++;
             }
             printf("\n");
             fprintf(ficlog,"\n");
             fprintf(ficres,"\n");
           }
         }
       }
       
       fprintf(ficres,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       if(mle >= 1) /* To big for the screen */
         printf("# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       fprintf(ficlog,"# Covariance matrix \n# 121 Var(a12)\n# 122 Cov(b12,a12) Var(b12)\n#   ...\n# 232 Cov(b23,a12)  Cov(b23,b12) ... Var (b23)\n");
       /* # 121 Var(a12)\n\ */
       /* # 122 Cov(b12,a12) Var(b12)\n\ */
       /* # 131 Cov(a13,a12) Cov(a13,b12, Var(a13)\n\ */
       /* # 132 Cov(b13,a12) Cov(b13,b12, Cov(b13,a13) Var(b13)\n\ */
       /* # 212 Cov(a21,a12) Cov(a21,b12, Cov(a21,a13) Cov(a21,b13) Var(a21)\n\ */
       /* # 212 Cov(b21,a12) Cov(b21,b12, Cov(b21,a13) Cov(b21,b13) Cov(b21,a21) Var(b21)\n\ */
       /* # 232 Cov(a23,a12) Cov(a23,b12, Cov(a23,a13) Cov(a23,b13) Cov(a23,a21) Cov(a23,b21) Var(a23)\n\ */
       /* # 232 Cov(b23,a12) Cov(b23,b12) ... Var (b23)\n" */
       
       
       /* Just to have a covariance matrix which will be more understandable
          even is we still don't want to manage dictionary of variables
       */
       for(itimes=1;itimes<=2;itimes++){
         jj=0;
         for(i=1; i <=nlstate; i++){
           for(j=1; j <=nlstate+ndeath; j++){
             if(j==i) continue;
             for(k=1; k<=ncovmodel;k++){
               jj++;
               ca[0]= k+'a'-1;ca[1]='\0';
               if(itimes==1){
                 if(mle>=1)
                   printf("#%1d%1d%d",i,j,k);
                 fprintf(ficlog,"#%1d%1d%d",i,j,k);
                 fprintf(ficres,"#%1d%1d%d",i,j,k);
               }else{
                 if(mle>=1)
                   printf("%1d%1d%d",i,j,k);
                 fprintf(ficlog,"%1d%1d%d",i,j,k);
                 fprintf(ficres,"%1d%1d%d",i,j,k);
               }
               ll=0;
               for(li=1;li <=nlstate; li++){
                 for(lj=1;lj <=nlstate+ndeath; lj++){
                   if(lj==li) continue;
                   for(lk=1;lk<=ncovmodel;lk++){
                     ll++;
                     if(ll<=jj){
                       cb[0]= lk +'a'-1;cb[1]='\0';
                       if(ll<jj){
                         if(itimes==1){
                           if(mle>=1)
                             printf(" Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                           fprintf(ficlog," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                           fprintf(ficres," Cov(%s%1d%1d,%s%1d%1d)",ca,i,j,cb, li,lj);
                         }else{
                           if(mle>=1)
                             printf(" %.5e",matcov[jj][ll]); 
                           fprintf(ficlog," %.5e",matcov[jj][ll]); 
                           fprintf(ficres," %.5e",matcov[jj][ll]); 
                         }
                       }else{
                         if(itimes==1){
                           if(mle>=1)
                             printf(" Var(%s%1d%1d)",ca,i,j);
                           fprintf(ficlog," Var(%s%1d%1d)",ca,i,j);
                           fprintf(ficres," Var(%s%1d%1d)",ca,i,j);
                         }else{
                           if(mle>=1)
                             printf(" %.7e",matcov[jj][ll]); 
                           fprintf(ficlog," %.7e",matcov[jj][ll]); 
                           fprintf(ficres," %.7e",matcov[jj][ll]); 
                         }
                       }
                     }
                   } /* end lk */
                 } /* end lj */
               } /* end li */
               if(mle>=1)
                 printf("\n");
               fprintf(ficlog,"\n");
               fprintf(ficres,"\n");
               numlinepar++;
             } /* end k*/
           } /*end j */
         } /* end i */
       } /* end itimes */
       
       fflush(ficlog);
       fflush(ficres);
         while(fgets(line, MAXLINE, ficpar)) {
       /* If line starts with a # it is a comment */
       if (line[0] == '#') {
         numlinepar++;
         fputs(line,stdout);
         fputs(line,ficparo);
         fputs(line,ficlog);
         continue;
       }else
         break;
     }
   
       /* while((c=getc(ficpar))=='#' && c!= EOF){ */
       /*   ungetc(c,ficpar); */
       /*   fgets(line, MAXLINE, ficpar); */
       /*   fputs(line,stdout); */
       /*   fputs(line,ficparo); */
       /* } */
       /* ungetc(c,ficpar); */
       
       estepm=0;
       if((num_filled=sscanf(line,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm, &ftolpl)) !=EOF){
   
       if (num_filled != 6) {
         printf("Not 6 parameters in line, for example:agemin=60 agemax=95 bage=55 fage=95 estepm=24 ftolpl=6e-4\n");
         printf("but line=%s\n",line);
         goto end;
       }
       printf("agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%lf\n",ageminpar,agemaxpar, bage, fage, estepm, ftolpl);
     }
     /* ftolpl=6*ftol*1.e5; /\* 6.e-3 make convergences in less than 80 loops for the prevalence limit *\/ */
     /*ftolpl=6.e-4;*/ /* 6.e-3 make convergences in less than 80 loops for the prevalence limit */
   
       /* fscanf(ficpar,"agemin=%lf agemax=%lf bage=%lf fage=%lf estepm=%d ftolpl=%\n",&ageminpar,&agemaxpar, &bage, &fage, &estepm); */
       if (estepm==0 || estepm < stepm) estepm=stepm;
       if (fage <= 2) {
         bage = ageminpar;
         fage = agemaxpar;
       }
       
       fprintf(ficres,"# agemin agemax for life expectancy, bage fage (if mle==0 ie no data nor Max likelihood).\n");
       fprintf(ficres,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
       fprintf(ficparo,"agemin=%.0f agemax=%.0f bage=%.0f fage=%.0f estepm=%d\n",ageminpar,agemaxpar,bage,fage, estepm);
   
       /* Other stuffs, more or less useful */    
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       fscanf(ficpar,"begin-prev-date=%lf/%lf/%lf end-prev-date=%lf/%lf/%lf mov_average=%d\n",&jprev1, &mprev1,&anprev1,&jprev2, &mprev2,&anprev2,&mobilav);
       fprintf(ficparo,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       fprintf(ficres,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       printf("begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       fprintf(ficlog,"begin-prev-date=%.lf/%.lf/%.lf end-prev-date=%.lf/%.lf/%.lf mov_average=%d\n",jprev1, mprev1,anprev1,jprev2, mprev2,anprev2,mobilav);
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       
       dateprev1=anprev1+(mprev1-1)/12.+(jprev1-1)/365.;
       dateprev2=anprev2+(mprev2-1)/12.+(jprev2-1)/365.;
       
       fscanf(ficpar,"pop_based=%d\n",&popbased);
       fprintf(ficlog,"pop_based=%d\n",popbased);
       fprintf(ficparo,"pop_based=%d\n",popbased);   
       fprintf(ficres,"pop_based=%d\n",popbased);   
       
       while((c=getc(ficpar))=='#' && c!= EOF){
         ungetc(c,ficpar);
         fgets(line, MAXLINE, ficpar);
         fputs(line,stdout);
         fputs(line,ficparo);
       }
       ungetc(c,ficpar);
       
       fscanf(ficpar,"prevforecast=%d starting-proj-date=%lf/%lf/%lf final-proj-date=%lf/%lf/%lf mobil_average=%d\n",&prevfcast,&jproj1,&mproj1,&anproj1,&jproj2,&mproj2,&anproj2,&mobilavproj);
       fprintf(ficparo,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       printf("prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       fprintf(ficlog,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       fprintf(ficres,"prevforecast=%d starting-proj-date=%.lf/%.lf/%.lf final-proj-date=%.lf/%.lf/%.lf mobil_average=%d\n",prevfcast,jproj1,mproj1,anproj1,jproj2,mproj2,anproj2,mobilavproj);
       /* day and month of proj2 are not used but only year anproj2.*/
       
       
       
        /* freqsummary(fileres, agemin, agemax, s, agev, nlstate, imx,Tvaraff,nbcode, ncodemax,mint,anint); */
       /* ,dateprev1,dateprev2,jprev1, mprev1,anprev1,jprev2, mprev2,anprev2); */
       
       replace_back_to_slash(pathc,pathcd); /* Even gnuplot wants a / */
       if(ageminpar == AGEOVERFLOW ||agemaxpar == -AGEOVERFLOW){
           printf("Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
   This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
   Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
           fprintf(ficlog,"Warning! Error in gnuplot file with ageminpar %f or agemaxpar %f overflow\n\
   This is probably because your parameter file doesn't \n  contain the exact number of lines (or columns) corresponding to your model line.\n\
   Please run with mle=-1 to get a correct covariance matrix.\n",ageminpar,agemaxpar);
       }else
         printinggnuplot(fileresu, optionfilefiname,ageminpar,agemaxpar,fage, pathc,p);
       
       printinghtml(fileresu,title,datafile, firstpass, lastpass, stepm, weightopt,\
                    model,imx,jmin,jmax,jmean,rfileres,popforecast,estepm,\
                    jprev1,mprev1,anprev1,jprev2,mprev2,anprev2);
         
      /*------------ free_vector  -------------*/
      /*  chdir(path); */
    
       free_ivector(wav,1,imx);
       free_imatrix(dh,1,lastpass-firstpass+1,1,imx);
       free_imatrix(bh,1,lastpass-firstpass+1,1,imx);
       free_imatrix(mw,1,lastpass-firstpass+1,1,imx);   
       free_lvector(num,1,n);
       free_vector(agedc,1,n);
       /*free_matrix(covar,0,NCOVMAX,1,n);*/
       /*free_matrix(covar,1,NCOVMAX,1,n);*/
       fclose(ficparo);
       fclose(ficres);
   
   
       /* Other results (useful)*/
   
   
       /*--------------- Prevalence limit  (period or stable prevalence) --------------*/
       /*#include "prevlim.h"*/  /* Use ficrespl, ficlog */
       prlim=matrix(1,nlstate,1,nlstate);
       prevalence_limit(p, prlim,  ageminpar, agemaxpar, ftolpl, &ncvyear);
       fclose(ficrespl);
   
   #ifdef FREEEXIT2
   #include "freeexit2.h"
   #endif
   
       /*------------- h Pij x at various ages ------------*/
       /*#include "hpijx.h"*/
       hPijx(p, bage, fage);
       fclose(ficrespij);
   
     /*-------------- Variance of one-step probabilities---*/
       k=1;
       varprob(optionfilefiname, matcov, p, delti, nlstate, bage, fage,k,Tvar,nbcode, ncodemax,strstart);
   
   
       probs= ma3x(1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
       for(i=1;i<=AGESUP;i++)
         for(j=1;j<=NCOVMAX;j++)
           for(k=1;k<=NCOVMAX;k++)
             probs[i][j][k]=0.;
   
       /*---------- Forecasting ------------------*/
       /*if((stepm == 1) && (strcmp(model,".")==0)){*/
       if(prevfcast==1){
         /*    if(stepm ==1){*/
         prevforecast(fileresu, anproj1, mproj1, jproj1, agemin, agemax, dateprev1, dateprev2, mobilavproj, bage, fage, firstpass, lastpass, anproj2, p, cptcoveff);
         /* (popforecast==1) populforecast(fileres, anpyram,mpyram,jpyram, agemin,agemax, dateprev1, dateprev2,mobilav, agedeb, fage, popforecast, popfile, anpyram1,p, i1);*/
         /*      }  */
         /*      else{ */
         /*        erreur=108; */
         /*        printf("Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model); */
         /*        fprintf(ficlog,"Warning %d!! You can only forecast the prevalences if the optimization\n  has been performed with stepm = 1 (month) instead of %d or model=. instead of '%s'\n", erreur, stepm, model); */
         /*      } */
       }
    
       /* ------ Other prevalence ratios------------ */
   
       /* Computes prevalence between agemin (i.e minimal age computed) and no more ageminpar */
   
       prevalence(probs, agemin, agemax, s, agev, nlstate, imx, Tvar, nbcode, ncodemax, mint, anint, dateprev1, dateprev2, firstpass, lastpass);
       /*  printf("ageminpar=%f, agemax=%f, s[lastpass][imx]=%d, agev[lastpass][imx]=%f, nlstate=%d, imx=%d,  mint[lastpass][imx]=%f, anint[lastpass][imx]=%f,dateprev1=%f, dateprev2=%f, firstpass=%d, lastpass=%d\n",\
           ageminpar, agemax, s[lastpass][imx], agev[lastpass][imx], nlstate, imx, mint[lastpass][imx],anint[lastpass][imx], dateprev1, dateprev2, firstpass, lastpass);
       */
   
       if (mobilav!=0) {
         mobaverage= ma3x(1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
         if (movingaverage(probs, bage, fage, mobaverage,mobilav)!=0){
           fprintf(ficlog," Error in movingaverage mobilav=%d\n",mobilav);
           printf(" Error in movingaverage mobilav=%d\n",mobilav);
         }
       }
   
   
       /*---------- Health expectancies, no variances ------------*/
   
       strcpy(filerese,"E_");
       strcat(filerese,fileresu);
       if((ficreseij=fopen(filerese,"w"))==NULL) {
         printf("Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
         fprintf(ficlog,"Problem with Health Exp. resultfile: %s\n", filerese); exit(0);
       }
       printf("Computing Health Expectancies: result on file '%s' ...", filerese);fflush(stdout);
       fprintf(ficlog,"Computing Health Expectancies: result on file '%s' ...", filerese);fflush(ficlog);
       /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
             
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
           fprintf(ficreseij,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) {
             fprintf(ficreseij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
           }
           fprintf(ficreseij,"******\n");
   
           eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           evsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, strstart);  
         
           free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
         /*}*/
       }
       fclose(ficreseij);
       printf("done evsij\n");fflush(stdout);
       fprintf(ficlog,"done evsij\n");fflush(ficlog);
   
       /*---------- Health expectancies and variances ------------*/
   
   
       strcpy(filerest,"T_");
       strcat(filerest,fileresu);
       if((ficrest=fopen(filerest,"w"))==NULL) {
         printf("Problem with total LE resultfile: %s\n", filerest);goto end;
         fprintf(ficlog,"Problem with total LE resultfile: %s\n", filerest);goto end;
       }
       printf("Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(stdout);
       fprintf(ficlog,"Computing Total Life expectancies with their standard errors: file '%s' ...\n", filerest); fflush(ficlog);
   
   
       strcpy(fileresstde,"STDE_");
       strcat(fileresstde,fileresu);
       if((ficresstdeij=fopen(fileresstde,"w"))==NULL) {
         printf("Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
         fprintf(ficlog,"Problem with Health Exp. and std errors resultfile: %s\n", fileresstde); exit(0);
       }
       printf("  Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);
       fprintf(ficlog,"  Computing Health Expectancies and standard errors: result on file '%s' \n", fileresstde);
   
       strcpy(filerescve,"CVE_");
       strcat(filerescve,fileresu);
       if((ficrescveij=fopen(filerescve,"w"))==NULL) {
         printf("Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);
         fprintf(ficlog,"Problem with Covar. Health Exp. resultfile: %s\n", filerescve); exit(0);
       }
       printf("    Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);
       fprintf(ficlog,"    Computing Covar. of Health Expectancies: result on file '%s' \n", filerescve);
   
       strcpy(fileresv,"V_");
       strcat(fileresv,fileresu);
       if((ficresvij=fopen(fileresv,"w"))==NULL) {
         printf("Problem with variance resultfile: %s\n", fileresv);exit(0);
         fprintf(ficlog,"Problem with variance resultfile: %s\n", fileresv);exit(0);
       }
       printf("      Computing Variance-covariance of DFLEs: file '%s' ... ", fileresv);fflush(stdout);
       fprintf(ficlog,"      Computing Variance-covariance of DFLEs: file '%s' ... ", fileresv);fflush(ficlog);
   
       /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
             
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
         fprintf(ficrest,"\n#****** ");
         for(j=1;j<=cptcoveff;j++) 
           fprintf(ficrest,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
         fprintf(ficrest,"******\n");
         
         fprintf(ficresstdeij,"\n#****** ");
         fprintf(ficrescveij,"\n#****** ");
         for(j=1;j<=cptcoveff;j++) {
           fprintf(ficresstdeij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
           fprintf(ficrescveij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
         }
         fprintf(ficresstdeij,"******\n");
         fprintf(ficrescveij,"******\n");
         
         fprintf(ficresvij,"\n#****** ");
         for(j=1;j<=cptcoveff;j++) 
           fprintf(ficresvij,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
         fprintf(ficresvij,"******\n");
         
         eij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
         oldm=oldms;savm=savms;
         printf(" cvevsij %d, ",k);
         fprintf(ficlog, " cvevsij %d, ",k);
         cvevsij(eij, p, nlstate, stepm, (int) bage, (int)fage, oldm, savm, k, estepm, delti, matcov, strstart);
         printf(" end cvevsij \n ");
         fprintf(ficlog, " end cvevsij \n ");
         
         /*
          */
         /* goto endfree; */
         
         vareij=ma3x(1,nlstate,1,nlstate,(int) bage, (int) fage);
         pstamp(ficrest);
         
         
         for(vpopbased=0; vpopbased <= popbased; vpopbased++){ /* Done for vpopbased=0 and vpopbased=1 if popbased==1*/
           oldm=oldms;savm=savms; /* ZZ Segmentation fault */
           cptcod= 0; /* To be deleted */
           printf("varevsij %d \n",vpopbased);
           fprintf(ficlog, "varevsij %d \n",vpopbased);
           varevsij(optionfilefiname, vareij, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, estepm, cptcov,cptcod,vpopbased,mobilav, strstart); /* cptcod not initialized Intel */
           fprintf(ficrest,"# Total life expectancy with std error and decomposition into time to be expected in each health state\n#  (weighted average of eij where weights are ");
           if(vpopbased==1)
             fprintf(ficrest,"the age specific prevalence observed (cross-sectionally) in the population i.e cross-sectionally\n in each health state (popbased=1) (mobilav=%d)\n",mobilav);
           else
             fprintf(ficrest,"the age specific period (stable) prevalences in each health state \n");
           fprintf(ficrest,"# Age popbased mobilav e.. (std) ");
           for (i=1;i<=nlstate;i++) fprintf(ficrest,"e.%d (std) ",i);
           fprintf(ficrest,"\n");
           /* printf("Which p?\n"); for(i=1;i<=npar;i++)printf("p[i=%d]=%lf,",i,p[i]);printf("\n"); */
           epj=vector(1,nlstate+1);
           printf("Computing age specific period (stable) prevalences in each health state \n");
           fprintf(ficlog,"Computing age specific period (stable) prevalences in each health state \n");
           for(age=bage; age <=fage ;age++){
             prevalim(prlim, nlstate, p, age, oldm, savm, ftolpl, &ncvyear, k); /*ZZ Is it the correct prevalim */
             if (vpopbased==1) {
               if(mobilav ==0){
                 for(i=1; i<=nlstate;i++)
                   prlim[i][i]=probs[(int)age][i][k];
               }else{ /* mobilav */ 
                 for(i=1; i<=nlstate;i++)
                   prlim[i][i]=mobaverage[(int)age][i][k];
               }
             }
             
             fprintf(ficrest," %4.0f %d %d",age, vpopbased, mobilav);
             /* fprintf(ficrest," %4.0f %d %d %d %d",age, vpopbased, mobilav,Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]); */ /* to be done */
             /* printf(" age %4.0f ",age); */
             for(j=1, epj[nlstate+1]=0.;j <=nlstate;j++){
               for(i=1, epj[j]=0.;i <=nlstate;i++) {
                 epj[j] += prlim[i][i]*eij[i][j][(int)age];
                 /*ZZZ  printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]);*/
                 /* printf("%lf %lf ", prlim[i][i] ,eij[i][j][(int)age]); */
               }
               epj[nlstate+1] +=epj[j];
             }
             /* printf(" age %4.0f \n",age); */
             
             for(i=1, vepp=0.;i <=nlstate;i++)
               for(j=1;j <=nlstate;j++)
                 vepp += vareij[i][j][(int)age];
             fprintf(ficrest," %7.3f (%7.3f)", epj[nlstate+1],sqrt(vepp));
             for(j=1;j <=nlstate;j++){
               fprintf(ficrest," %7.3f (%7.3f)", epj[j],sqrt(vareij[j][j][(int)age]));
             }
             fprintf(ficrest,"\n");
           }
         } /* End vpopbased */
         free_ma3x(eij,1,nlstate,1,nlstate,(int) bage, (int)fage);
         free_ma3x(vareij,1,nlstate,1,nlstate,(int) bage, (int)fage);
         free_vector(epj,1,nlstate+1);
         printf("done \n");fflush(stdout);
         fprintf(ficlog,"done\n");fflush(ficlog);
         
         /*}*/
       } /* End k */
       free_vector(weight,1,n);
       free_imatrix(Tvard,1,NCOVMAX,1,2);
       free_imatrix(s,1,maxwav+1,1,n);
       free_matrix(anint,1,maxwav,1,n); 
       free_matrix(mint,1,maxwav,1,n);
       free_ivector(cod,1,n);
       free_ivector(tab,1,NCOVMAX);
       fclose(ficresstdeij);
       fclose(ficrescveij);
       fclose(ficresvij);
       fclose(ficrest);
       printf("done Health expectancies\n");fflush(stdout);
       fprintf(ficlog,"done Health expectancies\n");fflush(ficlog);
       fclose(ficpar);
     
       /*------- Variance of period (stable) prevalence------*/   
   
       strcpy(fileresvpl,"VPL_");
       strcat(fileresvpl,fileresu);
       if((ficresvpl=fopen(fileresvpl,"w"))==NULL) {
         printf("Problem with variance of period (stable) prevalence  resultfile: %s\n", fileresvpl);
         exit(0);
       }
       printf("Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(stdout);
       fprintf(ficlog, "Computing Variance-covariance of period (stable) prevalence: file '%s' ...", fileresvpl);fflush(ficlog);
   
       /*for(cptcov=1,k=0;cptcov<=i1;cptcov++){
         for(cptcod=1;cptcod<=ncodemax[cptcov];cptcod++){*/
             
       for (k=1; k <= (int) pow(2,cptcoveff); k++){
           fprintf(ficresvpl,"\n#****** ");
           for(j=1;j<=cptcoveff;j++) 
             fprintf(ficresvpl,"V%d=%d ",Tvaraff[j],nbcode[Tvaraff[j]][codtabm(k,j)]);
           fprintf(ficresvpl,"******\n");
         
           varpl=matrix(1,nlstate,(int) bage, (int) fage);
           oldm=oldms;savm=savms;
           varprevlim(fileres, varpl, matcov, p, delti, nlstate, stepm, (int) bage, (int) fage, oldm, savm, prlim, ftolpl, &ncvyear, k, strstart);
           free_matrix(varpl,1,nlstate,(int) bage, (int)fage);
         /*}*/
       }
   
       fclose(ficresvpl);
       printf("done variance-covariance of period prevalence\n");fflush(stdout);
       fprintf(ficlog,"done variance-covariance of period prevalence\n");fflush(ficlog);
   
       /*---------- End : free ----------------*/
       if (mobilav!=0) free_ma3x(mobaverage,1, AGESUP,1,NCOVMAX, 1,NCOVMAX);
       free_ma3x(probs,1,AGESUP,1,NCOVMAX, 1,NCOVMAX);
     }  /* mle==-3 arrives here for freeing */
    /* endfree:*/
       free_matrix(prlim,1,nlstate,1,nlstate); /*here or after loop ? */
       free_matrix(pmmij,1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(oldms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(newms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(savms, 1,nlstate+ndeath,1,nlstate+ndeath);
       free_matrix(covar,0,NCOVMAX,1,n);
       free_matrix(matcov,1,npar,1,npar);
       free_matrix(hess,1,npar,1,npar);
       /*free_vector(delti,1,npar);*/
       free_ma3x(delti3,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel); 
       free_matrix(agev,1,maxwav,1,imx);
       free_ma3x(param,1,nlstate,1, nlstate+ndeath-1,1,ncovmodel);
   
       free_ivector(ncodemax,1,NCOVMAX);
       free_ivector(ncodemaxwundef,1,NCOVMAX);
       free_ivector(Tvar,1,NCOVMAX);
       free_ivector(Tprod,1,NCOVMAX);
       free_ivector(Tvaraff,1,NCOVMAX);
       free_ivector(Tage,1,NCOVMAX);
   
       free_imatrix(nbcode,0,NCOVMAX,0,NCOVMAX);
       /* free_imatrix(codtab,1,100,1,10); */
     fflush(fichtm);
     fflush(ficgp);
     
   
     if((nberr >0) || (nbwarn>0)){
       printf("End of Imach with %d errors and/or %d warnings\n",nberr,nbwarn);
       fprintf(ficlog,"End of Imach with %d errors and/or warnings %d\n",nberr,nbwarn);
     }else{
       printf("End of Imach\n");
       fprintf(ficlog,"End of Imach\n");
     }
     printf("See log file on %s\n",filelog);
     /*  gettimeofday(&end_time, (struct timezone*)0);*/  /* after time */
     /*(void) gettimeofday(&end_time,&tzp);*/
     rend_time = time(NULL);  
     end_time = *localtime(&rend_time);
     /* tml = *localtime(&end_time.tm_sec); */
     strcpy(strtend,asctime(&end_time));
     printf("Local time at start %s\nLocal time at end   %s",strstart, strtend); 
     fprintf(ficlog,"Local time at start %s\nLocal time at end   %s\n",strstart, strtend); 
     printf("Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
   
     printf("Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
     fprintf(ficlog,"Total time used %s\n", asc_diff_time(rend_time -rstart_time,tmpout));
     fprintf(ficlog,"Total time was %.0lf Sec.\n", difftime(rend_time,rstart_time));
     /*  printf("Total time was %d uSec.\n", total_usecs);*/
   /*   if(fileappend(fichtm,optionfilehtm)){ */
     fprintf(fichtm,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
     fclose(fichtm);
     fprintf(fichtmcov,"<br>Local time at start %s<br>Local time at end   %s<br>\n</body></html>",strstart, strtend);
     fclose(fichtmcov);
     fclose(ficgp);
     fclose(ficlog);
     /*------ End -----------*/
   
   
      printf("Before Current directory %s!\n",pathcd);
   #ifdef WIN32
      if (_chdir(pathcd) != 0)
              printf("Can't move to directory %s!\n",path);
      if(_getcwd(pathcd,MAXLINE) > 0)
   #else
      if(chdir(pathcd) != 0)
              printf("Can't move to directory %s!\n", path);
      if (getcwd(pathcd, MAXLINE) > 0)
   #endif 
       printf("Current directory %s!\n",pathcd);
     /*strcat(plotcmd,CHARSEPARATOR);*/
     sprintf(plotcmd,"gnuplot");
   #ifdef _WIN32
     sprintf(plotcmd,"\"%sgnuplot.exe\"",pathimach);
   #endif
     if(!stat(plotcmd,&info)){
       printf("Error or gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
       if(!stat(getenv("GNUPLOTBIN"),&info)){
         printf("Error or gnuplot program not found: '%s' Environment GNUPLOTBIN not set.\n",plotcmd);fflush(stdout);
       }else
         strcpy(pplotcmd,plotcmd);
   #ifdef __unix
       strcpy(plotcmd,GNUPLOTPROGRAM);
       if(!stat(plotcmd,&info)){
         printf("Error gnuplot program not found: '%s'\n",plotcmd);fflush(stdout);
       }else
         strcpy(pplotcmd,plotcmd);
   #endif
     }else
       strcpy(pplotcmd,plotcmd);
     
     sprintf(plotcmd,"%s %s",pplotcmd, optionfilegnuplot);
     printf("Starting graphs with: '%s'\n",plotcmd);fflush(stdout);
   
     if((outcmd=system(plotcmd)) != 0){
       printf("gnuplot command might not be in your path: '%s', err=%d\n", plotcmd, outcmd);
       printf("\n Trying if gnuplot resides on the same directory that IMaCh\n");
       sprintf(plotcmd,"%sgnuplot %s", pathimach, optionfilegnuplot);
       if((outcmd=system(plotcmd)) != 0)
         printf("\n Still a problem with gnuplot command %s, err=%d\n", plotcmd, outcmd);
     }
     printf(" Successful, please wait...");
     while (z[0] != 'q') {
       /* chdir(path); */
       printf("\nType e to edit results with your browser, g to graph again and q for exit: ");
       scanf("%s",z);
   /*     if (z[0] == 'c') system("./imach"); */
       if (z[0] == 'e') {
   #ifdef __APPLE__
         sprintf(pplotcmd, "open %s", optionfilehtm);
   #elif __linux
         sprintf(pplotcmd, "xdg-open %s", optionfilehtm);
   #else
         sprintf(pplotcmd, "%s", optionfilehtm);
   #endif
         printf("Starting browser with: %s",pplotcmd);fflush(stdout);
         system(pplotcmd);
       }
       else if (z[0] == 'g') system(plotcmd);
       else if (z[0] == 'q') exit(0);
     }
     end:
     while (z[0] != 'q') {
       printf("\nType  q for exiting: "); fflush(stdout);
       scanf("%s",z);
     }
   }

Removed from v.1.50  
changed lines
  Added in v.1.210


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